LOCUS       DAVBOU010000001        69737 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBOU010000001 DAVBOU010000000
VERSION     DAVBOU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.001"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            400..1041
                     /locus_tag="VQ879_000001"
     CDS             400..1041
                     /locus_tag="VQ879_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3142244.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            1054..1224
                     /locus_tag="VQ879_000002"
     CDS             1054..1224
                     /locus_tag="VQ879_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142245.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1720..3066)
                     /gene="gdhA"
                     /locus_tag="VQ879_000003"
     CDS             complement(1720..3066)
                     /gene="gdhA"
                     /locus_tag="VQ879_000003"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3142246.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            3598..4054
                     /locus_tag="VQ879_000004"
                     /pseudo
     CDS             3598..4054
                     /locus_tag="VQ879_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            4057..5069
                     /locus_tag="VQ879_000005"
                     /pseudo
     CDS             4057..5069
                     /locus_tag="VQ879_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            5044..5622
                     /locus_tag="VQ879_000006"
     CDS             5044..5622
                     /locus_tag="VQ879_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3142247.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(5679..5963)
                     /locus_tag="VQ879_000007"
     CDS             complement(5679..5963)
                     /locus_tag="VQ879_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3142248.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(6017..6952)
                     /locus_tag="VQ879_000008"
     CDS             complement(6017..6952)
                     /locus_tag="VQ879_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3142249.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            7056..7499
                     /locus_tag="VQ879_000009"
     CDS             7056..7499
                     /locus_tag="VQ879_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3142250.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            7615..7881
                     /locus_tag="VQ879_000010"
     CDS             7615..7881
                     /locus_tag="VQ879_000010"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3142251.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            7878..8252
                     /gene="crcB"
                     /locus_tag="VQ879_000011"
     CDS             7878..8252
                     /gene="crcB"
                     /locus_tag="VQ879_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3142252.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            8246..8575
                     /gene="crcB"
                     /locus_tag="VQ879_000012"
     CDS             8246..8575
                     /gene="crcB"
                     /locus_tag="VQ879_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3142253.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            8694..9041
                     /gene="rplS"
                     /locus_tag="VQ879_000013"
     CDS             8694..9041
                     /gene="rplS"
                     /locus_tag="VQ879_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3142254.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9083..9154
                     /locus_tag="VQ879_000014"
     tRNA            9083..9154
                     /locus_tag="VQ879_000014"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9116..9118,aa:Arg,seq:cct)
     gene            complement(9320..10318)
                     /locus_tag="VQ879_000015"
     CDS             complement(9320..10318)
                     /locus_tag="VQ879_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3142255.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(10361..11167)
                     /gene="yidA"
                     /locus_tag="VQ879_000016"
     CDS             complement(10361..11167)
                     /gene="yidA"
                     /locus_tag="VQ879_000016"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3142256.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(11180..12484)
                     /locus_tag="VQ879_000017"
     CDS             complement(11180..12484)
                     /locus_tag="VQ879_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3142257.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            12556..12933
                     /locus_tag="VQ879_000018"
     CDS             12556..12933
                     /locus_tag="VQ879_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3142258.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            13024..13356
                     /locus_tag="VQ879_000019"
     CDS             13024..13356
                     /locus_tag="VQ879_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3142259.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            13368..14939
                     /gene="ffh"
                     /locus_tag="VQ879_000020"
     CDS             13368..14939
                     /gene="ffh"
                     /locus_tag="VQ879_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3142260.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15134..16417)
                     /locus_tag="VQ879_000021"
     CDS             complement(15134..16417)
                     /locus_tag="VQ879_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3142261.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(16671..17384)
                     /gene="rsmG"
                     /locus_tag="VQ879_000022"
     CDS             complement(16671..17384)
                     /gene="rsmG"
                     /locus_tag="VQ879_000022"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3142262.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            17478..18038
                     /locus_tag="VQ879_000023"
     CDS             17478..18038
                     /locus_tag="VQ879_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3142263.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            18040..18939
                     /gene="htpX"
                     /locus_tag="VQ879_000024"
     CDS             18040..18939
                     /gene="htpX"
                     /locus_tag="VQ879_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3142264.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(18983..20542)
                     /locus_tag="VQ879_000025"
     CDS             complement(18983..20542)
                     /locus_tag="VQ879_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3142265.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            21267..21809
                     /locus_tag="VQ879_000026"
     CDS             21267..21809
                     /locus_tag="VQ879_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3142266.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            21809..22438
                     /gene="nth"
                     /locus_tag="VQ879_000027"
     CDS             21809..22438
                     /gene="nth"
                     /locus_tag="VQ879_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3142267.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            22649..23170
                     /gene="pyrR"
                     /locus_tag="VQ879_000028"
     CDS             22649..23170
                     /gene="pyrR"
                     /locus_tag="VQ879_000028"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3142268.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            23189..24112
                     /locus_tag="VQ879_000029"
     CDS             23189..24112
                     /locus_tag="VQ879_000029"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3142269.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            24162..25241
                     /gene="carA"
                     /locus_tag="VQ879_000030"
     CDS             24162..25241
                     /gene="carA"
                     /locus_tag="VQ879_000030"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3142270.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEKARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            25554..28730
                     /gene="carB"
                     /locus_tag="VQ879_000031"
     CDS             25554..28730
                     /gene="carB"
                     /locus_tag="VQ879_000031"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3142271.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(29005..29814)
                     /locus_tag="VQ879_000032"
     CDS             complement(29005..29814)
                     /locus_tag="VQ879_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3142272.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(29816..30619)
                     /locus_tag="VQ879_000033"
     CDS             complement(29816..30619)
                     /locus_tag="VQ879_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3142273.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(30629..32116)
                     /gene="tacF"
                     /locus_tag="VQ879_000034"
     CDS             complement(30629..32116)
                     /gene="tacF"
                     /locus_tag="VQ879_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3142274.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            32452..33159
                     /locus_tag="VQ879_000035"
     CDS             32452..33159
                     /locus_tag="VQ879_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3142275.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            33164..34186
                     /locus_tag="VQ879_000036"
     CDS             33164..34186
                     /locus_tag="VQ879_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3142276.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            34203..35072
                     /gene="licA"
                     /locus_tag="VQ879_000037"
     CDS             34203..35072
                     /gene="licA"
                     /locus_tag="VQ879_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3142277.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLVKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLVEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            35062..35940
                     /locus_tag="VQ879_000038"
     CDS             35062..35940
                     /locus_tag="VQ879_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3142278.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFNMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            35952..36641
                     /locus_tag="VQ879_000039"
     CDS             35952..36641
                     /locus_tag="VQ879_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3142279.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            36739..37587
                     /gene="dprA"
                     /locus_tag="VQ879_000040"
     CDS             36739..37587
                     /gene="dprA"
                     /locus_tag="VQ879_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3142280.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            38471..39514
                     /locus_tag="VQ879_000041"
     CDS             38471..39514
                     /locus_tag="VQ879_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3142281.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            39681..41768
                     /gene="topA"
                     /locus_tag="VQ879_000042"
     CDS             39681..41768
                     /gene="topA"
                     /locus_tag="VQ879_000042"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3142282.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            41874..42233
                     /locus_tag="VQ879_000043"
     CDS             41874..42233
                     /locus_tag="VQ879_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3142283.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            42326..42958
                     /locus_tag="VQ879_000044"
     CDS             42326..42958
                     /locus_tag="VQ879_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3142284.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            43002..43658
                     /locus_tag="VQ879_000045"
     CDS             43002..43658
                     /locus_tag="VQ879_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3142285.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            43677..44309
                     /locus_tag="VQ879_000046"
     CDS             43677..44309
                     /locus_tag="VQ879_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3142286.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            44337..44771
                     /locus_tag="VQ879_000047"
     CDS             44337..44771
                     /locus_tag="VQ879_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET3142287.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            44783..45820
                     /gene="leuB"
                     /locus_tag="VQ879_000048"
     CDS             44783..45820
                     /gene="leuB"
                     /locus_tag="VQ879_000048"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3142288.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            45817..46086
                     /locus_tag="VQ879_000049"
     CDS             45817..46086
                     /locus_tag="VQ879_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3142289.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            46090..46449
                     /gene="leuD"
                     /locus_tag="VQ879_000050"
     CDS             46090..46449
                     /gene="leuD"
                     /locus_tag="VQ879_000050"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3142290.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIVAYEKQRPAYWQD"
     gene            46611..47235
                     /locus_tag="VQ879_000051"
                     /pseudo
     CDS             46611..47235
                     /locus_tag="VQ879_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            47398..49311
                     /locus_tag="VQ879_000052"
     CDS             47398..49311
                     /locus_tag="VQ879_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3142291.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            49298..50614
                     /locus_tag="VQ879_000053"
     CDS             49298..50614
                     /locus_tag="VQ879_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3142292.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            50789..51775
                     /locus_tag="VQ879_000054"
     CDS             50789..51775
                     /locus_tag="VQ879_000054"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3142293.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            51839..51910
                     /locus_tag="VQ879_000055"
     tRNA            51839..51910
                     /locus_tag="VQ879_000055"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:51872..51874,aa:Arg,seq:ccg)
     gene            52093..52791
                     /locus_tag="VQ879_000056"
     CDS             52093..52791
                     /locus_tag="VQ879_000056"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3142294.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            52782..56321
                     /gene="smc"
                     /locus_tag="VQ879_000057"
     CDS             52782..56321
                     /gene="smc"
                     /locus_tag="VQ879_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3142295.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPQGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            56318..57112
                     /locus_tag="VQ879_000058"
     CDS             56318..57112
                     /locus_tag="VQ879_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3142296.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            57112..57930
                     /locus_tag="VQ879_000059"
     CDS             57112..57930
                     /locus_tag="VQ879_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3142297.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            57934..59223
                     /gene="ftsY"
                     /locus_tag="VQ879_000060"
     CDS             57934..59223
                     /gene="ftsY"
                     /locus_tag="VQ879_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3142298.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(59267..60754)
                     /locus_tag="VQ879_000061"
     CDS             complement(59267..60754)
                     /locus_tag="VQ879_000061"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3142299.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     VELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(60903..61643)
                     /locus_tag="VQ879_000062"
     CDS             complement(60903..61643)
                     /locus_tag="VQ879_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3142300.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(61643..63808)
                     /locus_tag="VQ879_000063"
     CDS             complement(61643..63808)
                     /locus_tag="VQ879_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3142301.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            63981..64934
                     /locus_tag="VQ879_000064"
     CDS             63981..64934
                     /locus_tag="VQ879_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3142302.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            65011..66999
                     /gene="uvrB"
                     /locus_tag="VQ879_000065"
     CDS             65011..66999
                     /gene="uvrB"
                     /locus_tag="VQ879_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3142303.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            67009..67572
                     /locus_tag="VQ879_000066"
     CDS             67009..67572
                     /locus_tag="VQ879_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142304.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            67538..68026
                     /locus_tag="VQ879_000067"
     CDS             67538..68026
                     /locus_tag="VQ879_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142305.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            68100..68567
                     /locus_tag="VQ879_000068"
     CDS             68100..68567
                     /locus_tag="VQ879_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3142306.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(68564..69079)
                     /locus_tag="VQ879_000069"
     CDS             complement(68564..69079)
                     /locus_tag="VQ879_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3142307.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(69091..69618)
                     /locus_tag="VQ879_000070"
     CDS             complement(69091..69618)
                     /locus_tag="VQ879_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3142308.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        21314 a        12471 c        15148 g        20804 t
ORIGIN      
        1 gatggtttac ctccttttca tcggtattca ccactttttc aatagtaaag acgagatggt
       61 cttgcggcaa gaaagaactg atttctagtg gtaaagttgt ttgatttgtg ttatagtgaa
      121 tatgcatggg atagcccttc taaatggttt attgggcaat tctattttac caagactatc
      181 gcaaccatgc aaaaaagcaa cggcaaatcc gcttcttttt tggagataag agactattgt
      241 cccagactct tagtactggt tggaggatac gatgaaagat agttattggt taaattattt
      301 tccggagtat agtttagaaa cgtttgaagt agaatagata ttaaggacct atctttctct
      361 tattccaaag actcagctct tgtaatagaa aatttaaatt tgactattga gtcaggacag
      421 agaattgcac tagtcggtca accggggtca ggaaaaagta cattatcaaa aataccatca
      481 ggattatata agattgatac aggaaaagtt ttatttgatg gtgtaaatat taatcaaata
      541 gataaaaaaa tattaagtca aaatttagga gtagttccac aggattcgtt tttattgaac
      601 agaagtattc ttgataacat aactttaaag cacgaagtta cttcacaaaa gatagaggaa
      661 gtttgtaaag cagttcaaat ctatgatgaa atcatggcta tgccgatgaa atttaatact
      721 atcatctcag agatgggttc aaatatttca ggtggtcaaa gacaacggat agcactggca
      781 cgtgcattaa taaataatcc tagtattgta attttagatg aagcaactag tgctttagac
      841 actattaatg aggaaagaat aacaaagtat ataaaaagtc agggctgtac tcaaataatt
      901 gtagctcata gattgtcaac gattaaggat gcggatatta ttgttgtaat gaaaggtggt
      961 aagattgttg agtcaggaaa tcataagtac ttaatggatc ttggtggaga gtactacagc
     1021 ttatatacaa aaaggaaatg aggtgtaaag aaaatgaaga aagaaaatga atatgtaatt
     1081 ttaacaacag cctcactagg ggtgatgatt ggaatagtgt ttgcaatttt tttagatttt
     1141 ccagttgaat atggtatttc tttaggattg ttgaatggaa tagtattggg ttcgctgatt
     1201 gtttacaaaa acaataagaa ttaagcataa ttttttgctg taaactaagg agtagagatg
     1261 gctatagttg aaattataaa tctaacaaaa agctttaaag atattgaagt tattcataac
     1321 acttaaataa tagagcaact acagtagtag cttaaaaaca tgattaaatc gctattctta
     1381 ggagtagcgt tttttctttt tgtttaatac tctttgaaaa tctcttcaaa ccacgtcagc
     1441 tttgccttgc cgtactcaag tacagcctgc gactcgcttc ctagtttgct ctttgatttt
     1501 cattgagtat aaaaagggtt aagtaagtat agtaaattga aataagatat gaacaaatcg
     1561 attagaaaag tcaaattaat ttctagaaat atgttagaaa ttggtttgaa ttccgcaatc
     1621 aatttgttca gtttttattt catttaatta gaatttccca actgtctaac tcaactaaaa
     1681 atccccaatc gtagtgattg aggattaagc aaataaatct taaacaatac cttgggcaat
     1741 catagcgttt gctacatttt caaaggcagc aatgttagct cctgcaaggt agtctttatc
     1801 aagaccgtat gtttctgaag tcgttttagc tgtgttgaag atgtttgtca tgatgtcttt
     1861 gagacggtca tcaacttctt cacgagtcca tgagaggcga agactgtttt ggctcatttc
     1921 aagagctgaa acggctacac caccagcgtt ggcagctttt gcaggtccgt ataagatacc
     1981 attttctttg taaactttga tggcatcaag gtcgctcggc atgttggcac cttcagatac
     2041 acagataatg ccttgagcaa ccaaacgttt agctgcttca ccgttgattt cgttttgagt
     2101 ggcacatgga agagcaatgt catagtttcc agcgtaagtc catacagtac cttcgtggta
     2161 ggttgcagtt gctttttcag ctgcatactc agtcaaacga gcacgacgtt tttctttaac
     2221 atcaaccaaa agatcgaagt cgataccatt ttcatcgatg acataaccat ttgagtcaga
     2281 aacagaaata acagttgcac cgagttcagt tgctttttga agagcatatt gagcaacgtt
     2341 accagaacct gaaataacga ctttcttacc agcaaagctg ttaccgttag ctttgagcat
     2401 ttcttcagta tagtaaacca aaccgtaacc agttgcttct ggacgaatca agctaccacc
     2461 aaatccaaga ggtttaccag tcaagacacc agcatcaaat tggttaagac gtttgtattg
     2521 accgtaaagg taaccaattt cacgtccacc aacaccgata tcaccagcag gtacgtcaag
     2581 tgatggtccg atgtgttttt gcaattcagt catgaagctt tggcagaagc gcatcacttc
     2641 agcatctgtt ttacctttag gatcgaagtc tgatccacct ttacctccac cgataggaag
     2701 tccagtcaag acatttttaa agatttgttc aaatccgagg aatttcaaga tcccttggtt
     2761 tacagttggg tggaaacgaa gtccaccttt gtatggtcca acagctgagt tgaattgaac
     2821 acggtaacca cggtttactt gaatttttcc atcacggtca acccaaggaa cacggaaaga
     2881 aaccacgcgc tcaggctcag taatacgtgc caagatattt tcttcgatat actcagggtg
     2941 tttttcaaat acaggttcta aagtgttgaa aaattcttca acagcttgga ggaattcagc
     3001 ctcgtgcccg ttacgagctt tcacagtttc aaacacgctt tggatatatt ctttagcaga
     3061 tgtcatatcg ttctcctttt attgtcatat tttattacat aagacattat agcagaattt
     3121 tttttcactg taaagaaaaa acagaaattt tctaaaaatt ctttcaattc agttttttgg
     3181 tttttttgaa aatagataaa aaaacgaacg tttttcttgg aaatatcttt ctcaaagaca
     3241 aaatcttaaa gtatgctata agaaaagaaa atgtttagca attcagaaat cacttgttaa
     3301 tttatccgtg atatgttaga tttgccagta aaactatgac cattttggag aaaagcaata
     3361 tttagactag actaaaataa aaaagtatta tataatagtg atatgaaatc aactaaagaa
     3421 gaaatccaaa ccatcaaaac acttttaaaa gactctcgta cagctaaata tcataaacgc
     3481 cttcaaatcg ttctatagta aaacgaaaca agaacagggc aaatcgatca ggacagtcaa
     3541 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     3601 tttcgtctga tgggcaaatc ttataaagag attatagagc ttttagactg taatcaaaca
     3661 acgatttggc gaaatgtaaa aaaatatgag gagttcggac tcgactctct ctttcaagaa
     3721 acacgtggtg gtcgtaacca tgcatatatg acggttgagc aagagaaagc ctttcttgct
     3781 cgccatttga aggctgcaga ggcaggagaa tttgttacaa ttgatgcctt atatcaggct
     3841 tataaaaagg agttaggtcg ttcctacaca cgtgatgcct tctatcaact gttgaagcac
     3901 catggttggc gaaatattat gccacgtcca gaacatccta ggaaagcaga cgctcaaacc
     3961 attgtcgcgt ctaaaaataa aatcttaatt caagaagaca agaaagcgct ttaaatatag
     4021 tagacgtttt cgtaaggttc gcttgatgta ccaaatagta cgcccatgca aaagaatatc
     4081 tattttgttg tcttggacct gcatacgacg gatagagata aaattatcca gctattcaag
     4141 gattggacgg attatagtgc caagttggtc gagggggaat tggttaaaaa agatggacag
     4201 aatgctctct ttcctccgag cgatactggt gagacagttg ggctcaatcc tcatcgtttg
     4261 acgctgactt ttggtgtatc tgcaagtttc ttgaaaaaga tgaacttgga aaacaagcgc
     4321 cctcgactgt tcagggattt acctctattt cctaaggagc aattacgtga aaaatatact
     4381 ggtggagata ttgtgattca tgcttgtgca gatgatgagc aaattgcctt tcacgctatt
     4441 cgcaatctca tacgtaaggg gagaaatgcg gtgccccttc gttggagtca gtctggattt
     4501 gcagctatcg gggaccgaat ggagactccg cggaacctct ttggttttaa ggatggaaca
     4561 gcaaatccaa ccaaggagca agactttgac cgcgttatct gggctgatag taaggactgg
     4621 atggaaaatg gttcttatat ggcagttcgt cggattcaga tgtttttaga gacctgggac
     4681 cgcactggtc tctaagaaca agaaaatacc tttggtcgtt acaaggaaag tagtgcccct
     4741 ttcggtaaaa aaatgagttt gatgaagtga atttgagttt tttgctagat gattcgcatg
     4801 ttcgtttggc taagtaagtg gacaagccac ttttgcgttg ttcttactct tactcagatg
     4861 gcattgatga aaagactggt cagtttgata cgggtttgct cttcatttct ttccagaagg
     4921 atcctgataa ctttgttaag gttcaaacta atctaggtgc tactgataag atgaatgaat
     4981 acatcactca cataggtagt ggacttttta cttgctttgg tggtgtggag aaaggagact
     5041 acattggtca gaaattattg gaaagctagg agctggttgc ttgttttagc tttgtcattt
     5101 ttaattcttt ccccagtagg tgcccaagaa agtttgagtt cttatttcgt aaaaatcaca
     5161 gatacttcta aagcggtcaa aaatggcaat cagtctgagg cccagaaact tgttcaagag
     5221 atggcatcag acttcgaaag agtagaaaat aaggattctg aggttggtaa gattgttaag
     5281 gaaaagttag ctctatctgg agatattact gaagccaaac tcaccgaaat ttcctcagct
     5341 ctattagctt ttgaaaaaga acaaaatcct gttgacctag atgcggaaaa ggaaaaattg
     5401 gtaaaccgtc taagtcctcg ttttgaaacc ttagagcagg ccattgcctc caaagatttg
     5461 gaaaaagtcc gagaagcttt taagaaaatg aattccactt ggaccatcaa tgaaagtgtg
     5521 gttcgtgaca atagtatagc tcattatgga cgtgttgaaa cagctatttc cttcctgcct
     5581 agtagcatgg aaaccgaacc tacagatgag tctggaacat gaaaacagca gttgatttca
     5641 agaaacaaaa aggaacagcc gaaactgttc tcttatcatt atttgagacc gtattttttg
     5701 ttgaaacgat ccacgcgtcc atctgcttga gtgaactttt gacgtccagt gtagaatggg
     5761 tgtgagtctg atgaaatttc cacacggatc aatgggtaag tctcgccttc gaactcaact
     5821 gtttcgttag agcgttttgt tgaaccgcta aggaattggt aaccagtagt tgtgtccatg
     5881 aagacaactg ggcgatattc tggatggata tcttttttca ttttgcaata tttcctttct
     5941 gccatggtct ctttgcgagc catagattgt taccatacta gtctatcaga ttctgaaaag
     6001 tttggcaagt attttatcag tttttaagca agttttttaa cttttggtag atgatttcgt
     6061 tttcctctag gctataggaa ttagcaccac ttgctagagg gtggcctcca ccatcatgtt
     6121 ccttggcaat ttcattgata ggatggattt tactgcgtaa gcgaacgcgg tagtggccat
     6181 cagcctgttc cacaaaaatt ccccagagac taacactatc aatacgccca ggtgcactta
     6241 caatggctgc agtttcagca tcggttacat tgtattgttt caagacttct tgactcagga
     6301 taacgcgagc agcaccattt tcatccactt ccagatggtc gtagatgtag ccttgcagtt
     6361 tagcaatttt gtagctcata gtgtccattt tgcgagtgag agccgcaaag tcaaagttat
     6421 gttctctcaa ataagcagcc aggcgaagag tccgtgcagt ggtagaaggg tagaggaagc
     6481 gacctgtatc accgacaatt cctgcaaaga gcaactcagc atcgcgatct gccaaggcta
     6541 gttgggttgt ttgggcaaat agggtaatca tctcgctagc gctacttgaa ctagtatcga
     6601 cccaagacag gtcaccgtat acatcatcat ttggatggtg gtcaatctta atgagaaaat
     6661 caccttgact atagcgttta tcatcgatac gagcagtatt agctgtatca cagacgatga
     6721 caagtgcgcc ttggtaggcc ctatcttcaa caagatccat ctcagccatc caagtaagag
     6781 ttggttcatc aaaaccgacg gctttgatgg ttttttctgg gaaatgatgt tccagcaagg
     6841 ctttcaatcc cacctgactt cccaaggcat cagggtctgg tttcatatga cgatgaatga
     6901 taatggtgtc gtattcttta attttttcta aaatttgttg gcaaatctcc ataaataacc
     6961 tcaattcttt ctcatttcat tgtagcacaa gaatttttat ttttaaaatg aaaaagatgt
     7021 gatataatgg agaaagataa attgaggagg acgatatggc attagcaaaa attgtatttg
     7081 ccagtatgac cggtaatacc gaagaaattg cagatattgt agcagacaaa ttacgtgact
     7141 tgggcttgga tgttgatgtt gatgaatgta caactgttga cgcttcagac ttcttggaag
     7201 cagacatcgc tatcgttgcg acctatactt atggtgatgg tgaattgcca gatgagatga
     7261 tggacttcta cgaagaccta gcagatctca acttgaatgg caaaatctac ggagtggtcg
     7321 gctcaggaga taccttctac gatgaattct gtaaggctgt tgatgacttt gaccgtgtct
     7381 ttgtgtcaac aggagcagaa aaaggttcag agtgtgttaa agttgatctt tctgccgagg
     7441 aagaagatat tgaacgcttg gaacaattcg cagaagaatt ggttgctaaa gtaggataag
     7501 cataaaagtg cgctgatgta atcaatcagt gcatttttct tatcgagagt tgggatttta
     7561 ctagcctaat tgatggcttt ttgatacaat aattcaaata aaggaggaga ctgtatggat
     7621 ttagatatta ttcgtcaaga aatcgatcaa atcgacgacc aaattgtcaa actgttagaa
     7681 gaacgaatgc atttagttga gggggtggtt gcttataaga aagcttcagg taaaccgatt
     7741 ttagatacta agagagaaga agttattttt gaaaaggttg ggagtcgtgt agaggacaag
     7801 cgctatcagg agactattgt agcgactttt tcggacatac tcaaacgttc gcgtgattat
     7861 caggatcaaa atatcaaatg aaaaaagaac aattttatcc gctaggaatt tttctagctg
     7921 ctatgttggg cggacttgtc cgatatctag tttccacctg gttaccagcc agtccagact
     7981 ttccttgggg cactctcttt gtcaactatc tgggaatttt ctgcttgatt tatcttgtca
     8041 agggctatct ggtctataag gggactagta agggcttgat tttagcactg gggacgggtt
     8101 tttgcggagg tttaacaact ttttccagcc taatgcttga tactgtgaag ctgcttgata
     8161 cagggcgtta tcttagtttg atactgtatt tgcttttgag tatcggtgga ggcctgcttt
     8221 tagcttacta tttggggagg aagaaatggt aatcgtctat cttgcaatcg cctgtggctt
     8281 gggagcactc gtacggtatt tcttttctcg ctataatcaa gtttctaaat tgccactcgg
     8341 aacgctcata gctaatcttt taggttgttt tttaattgga gtattctaca atcatgtaga
     8401 gtctaaggaa gtatatgcta ttctagcaac aggattttgt ggcggtttaa caactttttc
     8461 gaccttgaat gacgaacttc aaagactgct aagtgataag aaggtctttt attcttacct
     8521 gactttgact tacataggtg gtttggttgc gattttttta ggaattttgc tataaatttc
     8581 tttacttttt tttagaaatt tggtaaactg tatcttgtgt gtaatggacg cacaaaaata
     8641 cagtttatcc gctgaggaag attcctcaag attgacaaag ataggagaat aaaatgaatc
     8701 cattaatcca aagcttgact gaaggtcaac ttcgtacaga tatcccatca ttccgtcctg
     8761 gtgatactgt tcgtgtacac gcgaaagttg tcgaaggtaa ccgcgaacgt atccagattt
     8821 ttgaaggtgt tgttatcgca cgtaaaggtg ctggaatctc agaaaactac acagttcgta
     8881 aaatctctaa cggtgtaggt gttgagcgta tcttcccaat ccacactcca cgtgttgaaa
     8941 aaatcgaagt tgttcgttac ggtaaagtac gtcgtgcgaa attgtactac ttgcgtgctc
     9001 ttcaaggtaa agcagctcgt atcaaagaaa tccgtcgtta attcgactaa aaaactctgc
     9061 ttttcagcag agtttttatc tagctccctt agttcaatgg atataacaac tccctcctaa
     9121 ggagtagttg caggttcgat tcctgcaggg ggcagtaatt agatatcaaa gaagtttgtc
     9181 aaaaagtctt tgatattaaa agaacgcata atatagggga ttgtctccat aatattatgc
     9241 gttttattat tgaaaaattt gggcaatcat cagataaaat tgagactata tcgagtatat
     9301 aaatgtttgt atagtcaatt tattcaaaat cgtcaagttc taaattattt aaaggactat
     9361 aacattcata tttctttaag taattgttta tttcttcagc agtggaacga ggtaaattaa
     9421 ctcttaaata gtcaatatct tccttagata aaaaatgatt tgcattcaaa attgagaagc
     9481 gaaataatgc ttcatcaaaa gcaaaatcat aatcgtcatc agataatgat tccattaatg
     9541 tttgaatatg ttttagtgag tagtcaggta tcgaatcggg ataatatact ggataatcag
     9601 tggctgaaaa attgttttct aatcctgaaa tagtaattat caaagattct atgtaatata
     9661 ttaaagcatg tttaatatta ccttcttgtt ccaaatgtct tccctgagcc tttcgtgtgt
     9721 tagataagca tccaaaatct cctgatacag tattcctatg agcttgttta tttaagagac
     9781 tccattttat atcaccaaaa gttgctttaa aagagatatt gtttttttct ttacaataat
     9841 cttccatact tatgtcttta tcatagtatg ctttgatata gtcactatgt tcgataataa
     9901 gattttgtgc ttcttttgtt agtttaaatt cgaacggaat atctaatttg tcaacgttga
     9961 tattattaat tattcttgta attaattctg ctttttttcc agaagtagct aaattatgtt
    10021 tagataatat agtttttaat tctactactt taagatatga taaagtctta tttttagtga
    10081 agtatcctaa tttgtataat tgattgtgtg tagattcagg gtcaatttga agagagtatt
    10141 taaaatatct tgggaaatta taatttctcc ctgttttttg agtccaatct atgagtatga
    10201 gttgcccagg agtaaggccg cactctaatt tgtttaggta aaaattgtta caatcagaat
    10261 ttgtgtctct attatgatta ttttgtttta aattaaatag tttgctaaaa aaattcattg
    10321 gattttattg ctaatcaatt cttattgaaa aatgatactt ttacagtacc catgtacgga
    10381 tggcatgggc aacgccagat tcatcattag atttagtgat gtatttggcg atttttttga
    10441 tttctggatt tccattttcc atgacaacag ggttgccaac gacttccagc atggcacggt
    10501 cattttcttc gtctccgata gccatggttt catctttggt taatcctagt ttttcagcta
    10561 agtgagtaat agctgaaccc ttgtctacat tctttttaag gagttcgagg tagaaaggag
    10621 cagatttgtt gatagagtag tgctcgtaaa attcggctgg tattttttca atcgcagcat
    10681 cgagaatttc tggttcatcg ataaacatac atttaacaat ttctttgcca gccatttctt
    10741 caggggtacg gtagaagata ggcatgctga cgagggttga ttcgtgtaca gtgtatgttc
    10801 cgatattgcg atttgcagta tagataccgt ccttggtaat ggcatgcatg tggacaccga
    10861 gcttgcgact gaggaattcc atatccagat aatcctcata ggtcaaggat tcgctgataa
    10921 tctcatggcc agtagcagtt tcttggacaa gggcaccatt gaaggtcacc acatagtcac
    10981 cttggtctct caactgcaag tcgtctagaa gtttggcaac acctgcgatg gggcggccag
    11041 ttgcaatcac gactttgaca ccagcttctt tggcatcttg gatggcagaa aagacttcag
    11101 gagtgatttc cttttggctg ttgacaaggg ttccgtcgat atcaacggca attagtttaa
    11161 tactcataaa tttcctcttc tagtttttat ttggggtaaa atgatcgttc tcaatcaagt
    11221 ataaaaattg ctgggtaatg ctagcaaaga tactgttttg atctaacatt tctttcggaa
    11281 aatagaaacg attatctccg tgacgactac cagcaaggga ttggacgata ggagacaggc
    11341 tagagagttc ggccagttct ccattctttt gtaaaatctc aatctgtgtc cgtggatttt
    11401 cagattcggg acgatagata tcataaggga ggtcaaagtt cttatgaatg gcagtatagt
    11461 agtcgggatc aaagccaatg tcctcaacca attttctcat gctagcgagt tggtcttgat
    11521 cttcttgtga aaaggtaatg gatttaaaga ccttgcggtt gacaaagcgt tgcgataaat
    11581 ctgcgagaat tttgtcagga ctggtcatcc agagctggaa gtaggtattc atcacaccat
    11641 catctagagc cagatagtca gacaaggtca catttttttc aaagaaaggc aggaggtgtg
    11701 gggaagttcg tgcaaagaag tctttgtcct tagggtagag ttccttagcg cgcttgagaa
    11761 gattctgtag gagaacttcc atagcgcgtg ttgctgggtg gaaatagacc tgcatataca
    11821 tctggtagcg actgaggaca tagtcttcga tggcgtgcat gccattgcgc tgaaaggcga
    11881 taccattttc gataggacga atgactcgga ggattcgagt caggtcaaat tccccatagg
    11941 atgctcctgt aaaataggag tcacgcaaga gatagtccat gcgatctgcg tcaatctgac
    12001 tagaaatgag ttgtacgacc tgcttgttag gataggtatg gtctatgaca ctggcaactt
    12061 tctctggaaa atcgggcgct acttgtagca agacttggtg aatctctgtc tcaggacttt
    12121 gaataatctc ctgagtaata gcttcatggt ctgtatcaaa gagatgttca aaagtatggg
    12181 agtaggcgcc atgcccaagg tcatgtagga gagcagcgat catggtcaag agagactcgg
    12241 caggattcca ttcctcagga tatttttctt cgaaaatctc tgtgatgcgt cgtgcaattt
    12301 catagactcc tagacagtga gagaagcgac tgtgttctcc accgtggaag gtataactgg
    12361 aagttcccag ttgtttgatc cggcgcaaac gctgaaattc ttttgtatta atcaagtcat
    12421 agatgatttg attaatgaca tggatgtagt tgtgaactgg gtcacggaat actttttcgt
    12481 tcatatgacc attatagcaa aatcctgctc tttttggtaa aatagtagga caagagacaa
    12541 gaaagagggc ctgatgtgaa gattcggatg cgaaatacaa ttcagtttga tgagcagttg
    12601 gaagtgattg accagcttta tgatgtggaa gtgcatgaaa aaggagatta tagctacctg
    12661 cttttctata atgaggaaaa ggaaaaagta gtgattaaat ttcatggtca agaacttgtg
    12721 atgagccgat tttctaatcc caagaccatt atgcgctttc taaagaatag cgatagttta
    12781 gcctatattc ctacacctat gggcatgcag gagtttatca tccaaacgag ccattatcaa
    12841 gttgataggc aaaagattga actagattat caactacaaa atcaagaggg acatcctttt
    12901 gccagctatc aattggaaat tacttggggc taggctcatg tctttttcaa atttagctat
    12961 ctatcttctt ggatcggttt cctagtgtgg tagattaggc taatttttgg tataataaaa
    13021 gttatggaaa tcgaaaaaac caatcgtatg aatgcgctct ttgaatttta tgcggcgctt
    13081 ttgacagata agcaaatgaa ttatatcgag ctctactacg ctgatgatta cagccttgct
    13141 gaaattgccg aggagttcgg tgtcagtcgt caggctgtct atgacaatat caagcgaaca
    13201 gaaaagattc tggaagatta tgagatgaaa ttgcacatgt actcggacta tattgtccgc
    13261 agtcagattt ttgatcagat tttggagcgc tatcccaagg ataactttct gcaggagcag
    13321 atagaaattt taacaagcat tgataataga gaataagagg aagaaaaatg gcatttgaaa
    13381 gtttaacaga acgtttgcag aacgtcttta aaaatctacg taaaaaagga aaaatctctg
    13441 aatctgatgt ccaagaggca accaaagaaa ttcgcttggc cttgctcgag gccgacgttg
    13501 ccttgcctgt tgtaaaggac tttatcaaga aagttcgtga gcgtgcagtc gggcatgagg
    13561 tcattgatac acttaatcct gcgcaacaga ttattaaaat cgttgatgag gaactgacag
    13621 ccgttttagg ttctgatacg gcagaaatta tcaagtcacc taagattcca accatcatca
    13681 tgatggttgg tttacaaggg gctggtaaaa caacctttgc tggtaaattg gccaacaaac
    13741 tcaagaaaga agaaaatgct cgtcctttga tgattgcggc ggatatttat cgtccagctg
    13801 ccattgacca gcttaagacc ttgggacaac agattgatgt gcctgtcttt gcacttggaa
    13861 cagaagtacc agctgttgag attgtacgtc aaggtttgga gcaagcccaa actaatcata
    13921 acgactatgt cttgattgat actgcgggtc gtttgcagat tgatgagctc ctcatgaatg
    13981 agcttcgtga tgtgaaagca ttggctcaac caaatgaaat cttgcttgtc gttgatgcta
    14041 tgattggtca ggaagcagcc aatgttgcgc gtgagtttaa tgctcagttg gaagtgactg
    14101 gggtcatcct taccaagatt gatggcgata ctcgtggtgg tgctgctctg tctgttcgtc
    14161 acattactgg aaaaccaatc aagttcactg gtacaggtga aaagattacg gacattgaaa
    14221 ccttccaccc agaccgcatg tctagccgta tccttggtat gggggatatg ctcactttga
    14281 ttgagaaagc ttctcaggaa tacgatgaac aaaaagccct tgaaatggct gagaagatgc
    14341 gcgaaaacac ctttgatttt aatgatttca tcgatcaatt agatcaggtg caaaatatgg
    14401 ggccgatgga agacttgctc aagatgattc caggtatggc caacaatcca gcccttcaaa
    14461 acatgaaggt ggatgaacgc cagattgctc gtaaacgtgc cattgtgtct tcgatgacac
    14521 ctgaagagcg tgaaaaccca aatttgttaa atccaagccg tcgccgtcgt attgctgctg
    14581 gttctggaaa tacattcgtc gaagtcaata aattcatcaa ggactttaac caggctaaac
    14641 agctcatgca gggtgttatg tctggggata tgaataaaat gatgaagcaa atggggatta
    14701 atccaaataa ccttcctaaa aatatgccaa atatgggagg aatggatatg tctgcccttg
    14761 aaggaatgat gggacaaggc ggtatgcctg acttatcagc tctcggagga gcaggaatgc
    14821 cagatatgag ccagatgttt ggtggcggtt tgaaaggtaa aattggtgaa tttgccatga
    14881 aacagtccat gaaacgtatg gctaacaaaa tgaagaaagc gaagaagaaa cgcaagtaag
    14941 acaagagatt gatgcaaatc tcatttgatg agaaaataaa gtaaaaattt ctatgataaa
    15001 acgtatagta tcaaggtttt agaatatctg atattatacg ttttttgatt ttaataattt
    15061 tgttaagaca cttttattat ggtatgcgaa aaatccactc agctgtctga gtggattagg
    15121 tgtatttaga ctcttagtct ttattttcgt atggcaagat caagttcaag atgattcctg
    15181 tcatggctga aagggcagta cctgaaagtg taactggacc aagtttaagg atagctcctc
    15241 caagtccaag aaccaacata gcacttgcga tgatgaggtt tcgcatttga gcgaaatcaa
    15301 cacgttcttt aatcaagact ttcaaaccat tgctggcgat aaccccatag agaaggattg
    15361 acataccacc aagtacagcg tttggaatag ttgaaatcaa ggcagtgaat ttaccaagga
    15421 agctgagggc aatcgcgatg aaggcagcgt tacggataac tgagacagaa gcgatacgag
    15481 tcataccgat aacccctgta ttttctccgt aagttgtatt ggctggtcca ccaaggaagg
    15541 cagaaacaga agttgcgata ccgtcaccaa gaagagtacg gtgaagacct ggttctttta
    15601 agaattgacg accacagatt tgacccaaaa cagtatggtc tccgatatgt tcagaaattg
    15661 ttacgatagc gattggcaag atagcgatgg cttctggacc aaagtaaaga ttgtactctt
    15721 taaaggcacc acctgtgcta aatggcaagt agaaaccagg aatttcgaac cagttggctt
    15781 taagaactgg tgtaaagtca accaagccaa gagttagtgc gaaaaggtaa ccaccgataa
    15841 tggcaaagag gaatggaatg attcgtagga agccttttcc ttttgtattg ataaaggcag
    15901 caattaggaa agtaacaacg gctaccagag catttttcca atttccgtct gctacaagac
    15961 ctgcattggt aacagctgaa cctgcaagtc caagaccgat aacgatgatc ataggaccga
    16021 taatgattgg tggcaagagt ttatcaatcc attttgttcc tacaaatcgg atgctggtag
    16081 caacaaggac atagaccaaa ccagtcaaga taacccctgt ttgggcagca gatacatccc
    16141 cccccatttc tttcatagcc agtgacatag ctgtgataaa ggcaaatgaa gaacctagat
    16201 aaactggaac tttaaaacca gtagcaatca tgtagatgag tgttccaaca cctgaagcaa
    16261 aaagggcaac agatacaggc attcccaaaa tcaatggtac caagatggtc gcaccaaaca
    16321 tggcgaaaac gtgttggaag ctaaggagaa ttccttttcc atccgaagga cgttggtcaa
    16381 cgtctagtaa caaatcaaca gttgattctt gtttcatata aacctcactt ttgggcatca
    16441 gaaaagagcc cattatttta cagcaatagg ccctcagagt aagacttctc taaaatctag
    16501 actttaaaga gtttcaaata tttttgcgtc ttcgtcacct cacgggatga cattaaaaac
    16561 ctttgcttag gatagtatag cagaaaaaaa tgattttgta aatcattttt tcccgagcct
    16621 agaaataaaa gagcgaggct gattttgtaa acatttgttt actaaaaaat ttaaagtggg
    16681 cgtttatttg gcataccagc cttacgtgga tatttatttg gtgtttcttt tttcttttct
    16741 accactgtga tatagcgcgg atctctattc ggtagggcgt agctgagatt gtcttcgacc
    16801 ttactaaaaa ggagattgag ggcattctta gcttctaata attcctcagg cgcattgctg
    16861 gccttgagtg ccaatagttt gccaccaacc ttaaggtagg gaatagtcaa ttcagatagg
    16921 acctgcatac gggcaaccgc acgagctgtt acaaaatcat attgagcacg gaagttcttg
    16981 tcttgggcaa aatcttcggc acgtccgtgg tagaaatgaa ctccgttcaa atccagttct
    17041 tgagccaaga gttgtaggaa gttgatgcgc ttattgagtg aatcaataat ggtcacatct
    17101 aactccggat agagaatttt cattggtaga ctaggaaatc ctgccccagc cccgatatca
    17161 agaagtttga tagtttcatt gggaatcaaa ccttgaagaa tgggtgcaat cgaatcgtaa
    17221 aaatgtttga gataaacttc ttccttgtcc gtaatcgccg tcaaattaat cttctcattc
    17281 cactcgacca agagctcaaa ataacgttca aattgttctt tttgctggtt cgaaagtgga
    17341 agattctgct cggcaagcaa gttgtaaaat gtttctggtt tcatagttat ttccttcttt
    17401 agtatcatct tattttacca caatcataga aaatttgata tactggtact aatctaaaag
    17461 cagaaaggac ttatattatg acttggatta ttcttggagt tatcgctctt attgttattt
    17521 ttgtgattgt tagctataac ggtttggtta aaaatcgtat gcaaaccaag gaggcttgga
    17581 gtcagattga tgttcagttg aaacgtcgaa atgacctctt gccgaacttg attgagactg
    17641 taaaaggtta tgccaaatat gaaggttcta cccttgaaaa ggtggcagaa ctacgtaacc
    17701 aagtggcggc agcgacttca ccagcagaag ctatgaaagc cagtgatgcc ctcactcgtc
    17761 aggtttcagg tatttttgca gttgcagaaa gctatccaga tttgaaagct agtgctaact
    17821 ttgttaaatt gcaagaggag ttgacaaaca cagaaaataa aatttcttac tctcgtcaac
    17881 tctataacag tgttgtcagc aactacaatg taaaattaga aactttcccg agcaatatta
    17941 tcgctggaat gtttggattt aaagcggcag atttccttca aacacctgaa gaggaaaagt
    18001 cggttcctaa agttgatttt agcggtttag gtgactaaga tgttgtttga tcaaattgca
    18061 agcaataaac gaaaaacctg gattttgttg ctggtatttt tcctactctt agctcttgtt
    18121 ggttatgcgg ttggttatct ctttataaga tctggacttg gtggtttggt tatcgcactg
    18181 attatcggct ttatctacgc tttgtctatg atttttcaat cgacagagat tgtcatgtcc
    18241 atgaatggag cgcgtgaggt ggatgagcaa acggcaccag acctctacca tgtagtggaa
    18301 gatatggctc tggtcgctca gattcctatg ccccgtgttt tcatcattga tgatccagcc
    18361 ttaaatgcct ttgcgacagg ttctaatcct caaaatgcgg ctgttgctgc gacttcaggt
    18421 ctactagcta tcatgaatcg tgaagaacta gaagctgtta tgggacatga agtcagtcat
    18481 attcgtaatt atgatatccg tatttcgact attgcagttg cccttgctag tgctatcacc
    18541 atgctttctg gtatggcagg tcgtatgatg tggtggggtg gagcaggtcg cagacgaagt
    18601 gatgatgacc gagatggaaa tggtcttgaa atcattatgc tagtggtttc cctactagct
    18661 attgtactgg cacctctcgc tgcaaccttg gttcagctcg ctatttctcg tcagagggaa
    18721 tttctggcag atgcatctag tgttgagctg actcgcaatc cccagggaat gattaatgcc
    18781 ctagataagt tggacaatag caaaccgatg agtcgccacg tcgatgatgc tagcagtgct
    18841 ctttatatca atgatcccaa gaaaggtggg gggttccaaa aactctttta tacccaccca
    18901 cctatctcag aacggattga acgtttaaaa cagatgtaaa agaatccaga ggtcgtctct
    18961 ggatttttgc tatgttgcaa atttataaat cttctaaatt aactaactcc aaaccgtgtt
    19021 ctgtcatgcg atagatgatc gagcagactt cttttaagaa acgacggtca tgcgaaacag
    19081 tgatgagacc gcctggatag gttgcaaaga gttttctgat ttggggttga gaagtgggag
    19141 aaaagtttcg tgtgggttca tccagcagga gaaagtttgg tttgcgcagg actagatcca
    19201 aaagcaggag ttttccctgt tgtccgccag ataaggagcg aatttgatgc tgcatttctg
    19261 gataactgaa attgagactg gctaggtgag agtggatttt ctgaagttcc tctttttccc
    19321 cagttttgct gatataagct attggtgata aatccaattg tagttttttg tggtaatctt
    19381 gtggcataaa accaagggaa atctctcttt tatcattcag aagttgcttt aatttggcta
    19441 acagagttga tttcccaaca ccatttggcc cgataatacc gattttttct tgcccacgga
    19501 cagttagttg tagtttttga accaaaactc ggtcgtcaat ggacaaattt tctttttcca
    19561 gttggactaa gactttagaa gctggtaatg gttggatgtc tgaaaagaaa agttggattt
    19621 gttcctcttc aagtggtttt tgagtcatgg actgagctgc cttttcgtag cgtttttctt
    19681 gtgagaggac agttttcatc tttttagcca ataggcgacc ggcagtacta tctttggtag
    19741 ctcgaagcgc agtttctaca ttttgcttaa ctctccgatg tttttccatg gttttatcgt
    19801 aggctctttg gttgttagca gcttgctgac tttgtttggc aaaattagcc tttctctgct
    19861 cactatagct atcatagtct aaatgctcta ctagcgtttc cgcttcttta cggtgtttga
    19921 ccagtcgcaa gtgaacaata gtgtctgccg tttcagaaag aaagtcttca tcatgggaaa
    19981 tgaaaataac ggtttgcctg gtcttttgaa tctggccttt tagccaatca actgtctcaa
    20041 ggtctaggtc atttgaaggt tcatctaaaa atagaatctc aaagggtttg gctaactcat
    20101 ggataagctg aattttcaaa gcttctcccc ctgatagatt gccaatctct tggtcacttg
    20161 cgaaacgatt gctatcaaaa tgcaattcct ccgccaaacg atagaggata ctgtagtcta
    20221 aatcaataga atctaaaaag aagtagtcgt gtaaagtttt ctttttcagc tcctcgggaa
    20281 gtttttgagg aatgtaggcc agtgactgat agtcagattg gatgtttccc ttgatagtga
    20341 aatcagacaa agcttccccc attaaagttt taagtaaggt tgatttacca tttccttctt
    20401 cgccaataat agctaccttt tccccgtctt gtatggtcat gcttaggtca gagacaaggt
    20461 ctcgtaaatc tttgttttgt gtgatggtca ggtgattgat ttttatcata ctattgccct
    20521 ttctagaatg ttcatagtgc ataacaaaaa gctctacttt acctagtaga gcccaaagtc
    20581 tatgtcaaaa aaactctatt aacatgccag aaaaagggca taaaagagca cacaaaaaga
    20641 gacaaaaaca agatctacta aataaaggtt ctttatttga tagacttagt tgttcatgtc
    20701 tcccttacct cctagtatta gtatctttat actatacttt taaggaaatt ttgtcaacag
    20761 aaaactggaa attctatgct ctaaaatcca aaaacaggtc tatagagact tagtacgtgt
    20821 ttgacatgct cgtaatggat tttatcatag tttcgccaag cagtgcgttc ttgattgttt
    20881 agttttaggc tacccagtcc aatcatagga ctggtgggtt ggtaaaattt ctcaagatca
    20941 attaagatac tgttgttcaa cttttccgtt ttttgagttc ttgcatagta gtgtttagca
    21001 gctcttgtag tcgaatatca tctgccgtac cctgtttaca gttttggtag cttttattta
    21061 acttggatag gagttgaatg agtttcttgt cttccgtgtg agcatcctcc ttgatctgat
    21121 gtactctttc cctatagtat agcactaaaa aataaaactg tcatagtgaa tatgttaaaa
    21181 tttcgaattt taattacaaa gtttggtgtg ctgatttgta gccttttcat ggtataatca
    21241 agagagtaaa tctttatgga ggaagtatga aattaaatat tcaagaaatt cgtaagcagt
    21301 ctgaaggttt gaactttgaa caaacgttag atttagttga tgacctgcgt gcacgtaatc
    21361 aagaaatttt agatgtaaaa gatatccttg cagttgggaa agtacaatat gaagaccgta
    21421 tgtatttctt agattatcaa ctatcttata ccattgttct tgcttcgagt cgcagtatgg
    21481 agccagttga gttagttgaa tcttatccag tcacggaagt tttcatggaa ggcgcaacta
    21541 accagctaga tcaagaagtt ttagatgatg acttggtctt gcccatcgaa aatggggagc
    21601 ttgaccttgc tgagagtgta tcagacaata tcctgctaaa cattcctatc aaggtcttga
    21661 cggctgaaga agaagctggt caaggatttg tctcaggaaa tgactggcaa atcatgacag
    21721 aggaagaata ccaagctcaa caagcagtaa agaaagaaga aaacagtcct tttgctggct
    21781 tacaaggact atttgacgga gatgaataat ggtcttgtca aaaaaacgag cacgaaaggt
    21841 gctagaagaa atcattgccc tcttcccaga tgccaagcct agtcttgatt ttaccaatca
    21901 ttttgaactc ctggttgcgg tcatgttatc agcccagacg acagatgcag cggtaaataa
    21961 ggccacacca ggtctctttg ttgcctttcc aacaccccaa gctatgtctg tagcgacaga
    22021 gagtgagatt gcttcacata tttctcgctt gggattgtat cggaataaag ctaaattcct
    22081 taaaaaatgt gcccaacagt tactagacga ttttgatggt caagtccctc agacacgtga
    22141 agaattggag agtttggcag gtgttggtcg caagacagcc aatgttgtca tgagtgtagg
    22201 atttgggatt ccagcctttg cagtggatac tcatgtggag cgtatttgca aacaccacga
    22261 tattgtcaaa aaatcagcga cgccacttga ggtggaaaag cgggtcatgg atatcttgcc
    22321 gcctgagcag tggttagctg cccatcaggc catgatttat tttggaagag ccatttgcca
    22381 tccaaaaaat ccagagtgtg accagtaccc acaattatat gattttagca atttgtaaga
    22441 tgctacattg aaactttttg cttgatttta agcatgcttt gtgctatagt aaatgataac
    22501 taaatattcc tttaaacctg tcccgtgagg caggcaagga gcgcgataaa gtagaagggt
    22561 gaagtctata ctgtgtgcag tagggctcgc ttggctataa atttcaagtc tccttgttta
    22621 aggagacttt tctttttgga ggtttgtcat gaaaacaaaa gaagttgtag acgaattgac
    22681 cgtcaaacga gcgattacgc gtattactta tgagattatc gaacgcaaca aagatttgaa
    22741 taagattgtc ttggctggta ttaaaactcg tggtgtcttt attgcccacc gaatccaaga
    22801 acgtttgaag cagttagaaa atctttcagt tcctgttgtg gaattggata ctaaaccttt
    22861 ccgtgatgat gttaaaagtg gagaagatac ttctttggtt tctgtcgatg tgacagaccg
    22921 cgaagttatc ttggtggatg atgtgctcta tacaggtcgt accatccgtg ctgctattga
    22981 taatattgtc ggtcatggtc gtcctgcgcg tgtgagttta gcagttctag tcgatcgtgg
    23041 acatagagaa ttgccaatcc gtccagatta cgttggaaaa aatatcccaa ccagtcgttc
    23101 tgaagaaatc atcgtagaga tgacagaact tgatgaccaa gacagagttc tgattactga
    23161 agaagcttag aaagttaaag gagtagccat gtcagaaaat caacaagcat tgaaccatgt
    23221 ggtgtccatg gaagacctca ctgtcgatca agtaatgaaa ttgatcaagc gaggaattga
    23281 gtttaaaaat ggagcccagc ttccctatga agaccatccg attgtttcca atctcttctt
    23341 tgaggattct acacggacac ataagtcctt tgaagtcgca gagattaaac ttggattgga
    23401 acgacttgac tttgatgtga agactagttc ggttaataag ggtgagacac tttatgacac
    23461 cattttgact ctgtctgctt taggagtgga tgtctgtgtg attcgccatc cagaggtcga
    23521 ctactataga gaattgattg ctagtccaac gattacgact tccatcatca atggtggaga
    23581 tggttcgggc caacacccta gccagagctt gcttgatttg atgaccattt atgaggaatt
    23641 tggccacttt gagggtctta aagttgctat tgcaggtgac ttggaccact cacgcgttgc
    23701 caaatccaat atgcagattt tgaaacgctt gggatctgaa ctctttttcg ctggacctga
    23761 ggaatggaga agtcaagagt ttgcagacta tggacagttt gtaaccattg atgaaatcat
    23821 tgatcaggtt gatgtcatga tgtttctccg tgtgcaacac gaacgccatg atagtggagc
    23881 tgtattttca aaagaagact accatgccca acatggcttg actcaagaac gttacgatcg
    23941 tttgaaagaa acagcaatcc tcatgcaccc agctccaatc aatcgtgatg tagaaatagc
    24001 agaccacttg gttgaagcac caaaatcacg gattgtccaa caaatgacca atggtgtctt
    24061 tgttcgaatg gcaatcttag aatccgtact agcgagtaga aacgccaact aaaacacaag
    24121 acgttaaaag acgccagtga gcgtccacga gaggtgaaaa tatgacaaaa agaattctag
    24181 tattagaaga tggcacagtt tttgaaggca aggccttcgg agcagatatt gatgtaacag
    24241 gcgaaatcgt ctttaataca gggatgaccg gctaccaaga atccattaca gaccagtctt
    24301 ataatggaca aatcttgacc tttacttatc ctttggtcgg aaactatgga attaaccgtg
    24361 atgattacga atctattatt ccaacttgta agggagttgt tgttttcgaa aaagcgcgta
    24421 gagcaagcaa ctggcgcaac caaatgacct tggatgaatt tttgaaagcc aagaaaattc
    24481 ctggtatttc agggattgat acgcgtgcac ttaccaagat tattcgtaag catggtacta
    24541 tgcgagcaac cttgactcat gttggagata gtatggacca tgtgactgac cagctccaag
    24601 caacagtatt gccgacagat aatattaagc aggtttctac taaaacttcc tatccagctc
    24661 caggagttgg tttgagcgtg gtgttagtag actttggtct caagcactca atcctacgtg
    24721 aactttctaa gcgcaactgt aatgtgacgg ttgttcctta ttcgacaacg gctgaagaaa
    24781 ttctccatct caatcctgac ggagtgatgt tgtcaaacgg tccaggtaac ccagaagatg
    24841 ttccacaggc actggatatg attcgcggtg tacaaggaaa aattccaatc tttggtatct
    24901 gtatgggaca tcaactcttt gctatggcaa acggggctaa gacctataag atgaagtttg
    24961 gccaccgtgg attcaaccat gcggtacgtg aaatcgcaac aggacgagta gacttcacca
    25021 gccagaacca tggttatgca gtcagccgcg aggatttgcc agagcacttg attattaccc
    25081 acgaagaaat caatgacaag tcagtggaag gtgtgcgcca cagataccaa cctgctttct
    25141 ctgttcaata ccacccagat gcagctcctg ggccacacga cgctagctac ctatttgacg
    25201 agtttatcga gatgatggaa gtttttaaac aatcaaacta agaacgagta aaagctcgtc
    25261 ggagaattta tgtaactgaa cacggacgga aagctcagaa tttagagaaa ccaacttgga
    25321 ttgtcaatcc ttccttgatt tcttaaaatt caatcgcttt ctattcgtcc tttgtatctt
    25381 atttaatgtc gccctgagag gcgacgaata gaaaggagaa gggtgctccg tatttgctga
    25441 actgaatacg ggctacggac ggtgctaaaa agatagttat tcctagaact gacagttctt
    25501 cgtcataact cctattttag ctttgtccgc ttgacgccct taatatctta tatatgccta
    25561 aacgtactga tattcaaaaa attatggtga ttggttctgg tccgattatt attggtcagg
    25621 ctgctgagtt tgactatgct gggacccagg cttgcttgtc gttgaaagag gaaggttatg
    25681 aggttgtttt ggttaactca aatcctgcaa ccatcatgac ggacaaggaa attgctgaca
    25741 aggtttacat tgaaccgatt acacttgagt ttgtgacacg tattcttcgt aaggaacgtc
    25801 cagatgcctt gctaccaaca ctcggtggtc agacaggtct caacatggcc atggaattgt
    25861 ctaaaaatgg tatcttagat gagcttagcg ttgaacttct gggtactaaa ttgtctgcca
    25921 ttgaccaagc ggaggaccgt gacctcttta aacaattgat ggaagagctt gagcaaccca
    25981 ttccagaatc tgaaattgtt aacacagtag aagaagcagt tgcctttgca gcgacaattg
    26041 gctacccagt catcgttcgt ccagccttta cccttggtgg tactggtggt ggtatgtgtg
    26101 ccaacgagaa agaattgcgt gaaatcactg aaaatggttt gaaattgtca cctgttaccc
    26161 aatgtttgat tgagcgttcg attgctggtt tcaaggaaat tgaatacgaa gtgatgcgtg
    26221 actcagctga caatgccttg gttgtttgta acatggaaaa ctttgaccca gttgggattc
    26281 acacggggga ttccattgta tttgcccctg cgcaaaccat gtcagactat gaaaaccaaa
    26341 tgcttcgtga tgcgagcttg agcattattc gtgccctcaa gattgaaggt ggatgtaatg
    26401 ttcagctagc tcttgatcct aacagcttca agtattatgt tatcgaagta aaccctcgtg
    26461 tatcacgttc gtcagccctt gcttctaaag cgacaggata tccgattgct aagttggctg
    26521 ccaagattgc agtaggtttg accttggatg aggttataaa cccagttaca ggttcaacct
    26581 atgccatgtt tgaaccagcc cttgactacg tagttgctaa gattccacgt ttcccatttg
    26641 acaagtttga aaagggtgaa cgccgtctcg gtacacaaat gaaggcgact ggagaagtca
    26701 tggcaatcgg tcgtaacatc gaggaatctc ttctcaaggc ctgccgctcc cttgaaattg
    26761 gggtgcacca caatgaaata cctgaacttg cagcagtttc tgatgatgcc ttgattgaaa
    26821 aggttgtcaa agcccaagat gaccgtctct tctacgtatc agaagcaatt cgtcgtggct
    26881 acacacctga agaaattgca gagcttacaa aaattgatat cttctatctt gataaactct
    26941 tgcatatctt tgaaattgag caagaattgg gtgctcatcc acaagatcta gaagttttga
    27001 aaacagccaa acttaatggt ttttcagacc gtaagattgc tgaactctgg ggaacgactg
    27061 atgataaagt tcgccaactt cgcttggaaa acaagattgt tccagtttat aagatggtag
    27121 acacttgtgc ggcagagttc gactccgaaa cgccatattt ctattcaacc tatggttggg
    27181 aaaatgaatc tatcagatct gataaagaat ctgtacttgt cctaggttca ggtccaatcc
    27241 gtatcggtca aggggttgag tttgactacg caaccgttca ctctgttaag gctatccagg
    27301 cagctggtta tgaagctatc atcatgaact caaacccaga gaccgtttca acagacttct
    27361 ctgtatcaga taagctttac tttgagccat tgacattcga agatgttatg aacgtcattg
    27421 acttggaaca accaaaggga gttatcgttc agttcggtgg tcaaacagcc atcaaccttg
    27481 cggagccatt ggcaaaagca ggtgtgacca tccttggtac acaggttgct gacctagacc
    27541 gtgccgaaga ccgtgacctc ttcgagcaag ctctcaaaga attggatatt ccacagccac
    27601 caggacaaac ggctaccaat gaagaagaag cagctcttgc agctcgtaag attggcttcc
    27661 cagttcttgt ccgcccatct tatgtacttg gtggacgtgc catggaaatc gttgaaaacg
    27721 aagaagacct tcgttcttac atgcgaactg ctgttaaggc tagtccagat cacccagttc
    27781 ttgtcgactc ttatatcgtt gggcaagagt gcgaagttga tgccatttca gatggtaaag
    27841 atgtgctcat tcctggtatc atggagcata tcgaacgtgc tggtgtccac tcaggtgact
    27901 caatggctgt ttacccacca caaaccttgt cgcaaaaggt tcaggagacc atcgcagact
    27961 acaccaaacg cttagcaatc ggtcttcact gccttggaat gatgaacatc cagtttgtta
    28021 tcaaggatga aaaagtctac gttattgagg tcaatccacg tgccagccgt actgttccat
    28081 tcctatctaa ggtaaccaat attcctatgg ctcaagtagc gaccaagctc attcttggtc
    28141 aaagtttatc agaacttggc taccaaaatg gactttaccc tgaaagcacc cgtgttcata
    28201 tcaaggcacc tgtcttctcc tttaccaaac tagctaaggt agacagcttg ctcggtcctg
    28261 aaatgaagtc aacaggtgaa gttatgggtt ctgatgctac tttggaaaaa gctctctata
    28321 aagcctttga agcttcttat ctacacttgc caacttttgg taatgtcgtc tttaccatcg
    28381 ctgatgatgc caaagaagaa gccttgaact tggctcgtcg tttccaaaac attggttatg
    28441 gaatccttgc gacagaaggg acagcagcct tctttgctag tcatggcttg caagcccaac
    28501 ctgttggtaa gattggtgat gacgataagg atatcccaag ttttgtacgc aaaggaagaa
    28561 ttcaagctat cattaacaca gtaggaacaa aacgaactgc tgacgaagat ggtgagcaaa
    28621 ttcgtcgttc agccattgaa cacggggtgc ccctcttcac agcgctagat acagctaatg
    28681 ccatgcttaa ggtacttgaa agtcgtagct ttgttacaga agcgatttaa atagaaaaat
    28741 aagatatagc agactgaatt tagaacagta cacaggaata ctaaaatatt tctataaatt
    28801 aatttgaatt ttctaattga tttgttcgca tcttatttca atctactata gaaaaaagtc
    28861 tttaaaatta taaaacgcat catatcaagg tttttcaaaa accttgatat gatgcgtttt
    28921 attgtgggaa tatgtatttc attttctact aaaattatgt ttttgaataa cctctatctt
    28981 agtagtttgt ataatccccc tcaatcagtt tttgcgataa gctttaatgc tatgactata
    29041 ccactcttgc atttcttttg atggtggtgt catataatcg ccatacatct gggttaaaaa
    29101 ttggtcatat tttttgggaa caggcaacat acggccctca aactcagtta aaatcagttc
    29161 tttaaaggta tcaactggga agatttcttt catcccttcc ttaccgatcc caactcctcc
    29221 ttcatattga ggaatgttgg ttacagcatt tttgactagt tgatcaattt tcttgtaaaa
    29281 gtagcgagga ttgacaaatc ggagagcgta ccagctacat aatctaagaa aatcttttag
    29341 tttgctatca ccgtgaactg ctcgtgattt tttgatataa gctagttgac gaagagccac
    29401 atacttatag ctcttgtcga caatgctcaa gtctgtaaat cgatcaattg ggaagacatc
    29461 gatgaaaagg ctggtatcat gacgcttgta cttaacatgg tcttctataa cagtagaagt
    29521 gtccaaaatc gatgcgaaat tatggaagta ccaagaagat gtatcgtagg aaagaacctt
    29581 gtagcgaggg tgattttctt cttcaataat cttcagtaaa cgctcataat cctcacgata
    29641 aagggaaata tcaatatcat catcccaagg aatcatacct ttgtggcgga tggctccaag
    29701 catggttcca taactgagaa aataaggaat atcatgtttc ttacaagtct catcaatata
    29761 gtccagcagg gctagttgaa tttctttaat ttcttttttt tctaaatatt gcatcctaat
    29821 cctccaattt ataagcgtga aattcatgac tgtagaagcg tttttcttct ggtggtaggg
    29881 tcatataatc tccataaaat tgtgtcaaaa tagtatcaaa tttttcaggt gcaggaaggc
    29941 ttaaattctc aaagggtaaa tcgattgttt tatcaaaggt accacttggg aagacttcct
    30001 tttccttaaa ttttgaaggg ataaaagcca tatactgccc attttcacga ctatattttt
    30061 gaatttcttt ctcgatttta tttgcaaaat aacgaggaga aactggtcga aggagcaacc
    30121 aaaaggctgt tcgtatccaa tcttttaaaa ggctatcctt atagacaata tttttatgtt
    30181 tactgaaaga cagcagtttg aagctttcca gtttataaca agtatcaatg accttaggat
    30241 catcaaagcg atctataggg aaaatatcga taaagatacc agactcatag gtttttgtat
    30301 ttcgagtatc aataatttta gtcgtactgt cggttatctt gataaagttg ttaaagtagt
    30361 tcttatcagt ttctaaggat aggagcttat acttgctttt ttccttttga aaaatgttaa
    30421 taaatcgttg gtagtcttct ctaggcatgg ataaatcaat atcgtcgtcc caagggataa
    30481 agccctcatg tcgaaccgcc ccaatcagag taccgtagtt aataatatag ttgatattgt
    30541 gctttttaca gagagtatca atataatcca aaatttctaa ttcaatttgt ttggcatctt
    30601 caatggttag ttgtttcatt ttaaactcct atgatttttt gaatttattt tttaaggcta
    30661 ggacatggtt taaaaattca tagaaaatgc tatcttttgt gaagacaagt agactaatat
    30721 aagagatagc tgatagcaag acaatcaaac cagtattaat taaaaatggc aaattaatga
    30781 ccatatccac aggatacacg aaattaatca ggaaataaat tgctacaaag gaaagtgaaa
    30841 agagagagta tcgaacagta tagctaaaga tatgtcccaa gtggatgagt tgttttctat
    30901 ggatgaaaat aatatagaaa acaagtagag aagtctctga taacatagtt gtcagtaagt
    30961 agtattcagg aaccacgata tggttgaaaa agaggagact attcaagccc aaattgagta
    31021 gcccagcaaa gactgtatag actgtgatac gtttttcata gccattggta aagagaattt
    31081 gggaaccaag aatggtatct aaggccagga taatcgtacg aaaagcgaag agagaggtca
    31141 agatgccgcc tccgatatat ttttcactac cgtaaagtag gatggcattt ggtcctaaaa
    31201 ccatgagtcc aaaactcagt ggaatgataa agaagttaaa gattcgacta cctctattaa
    31261 ccagagaaac ataggcttct ttgtctcctt tccccagata gtaactgaga cgaggcacac
    31321 tcactccaat tgcacctgtt acaaccccag ctataacggt cacaattcgc tgagctatgg
    31381 tatagtaact aacgttgaca tcaatccctg ttttaacgag gaagaggcga tctaaaaaag
    31441 tgaagagcat attggcattg gcaaagacta acatggctgt cagagggaga aagagtggtt
    31501 taaaatcact taggtgaatc ttaacaagtt tgatgtctct tttaatccaa aaataactaa
    31561 tcaggtagtt aatcagcgtc gataaactca tcacaagtgt atagacaaca atatcgtgtt
    31621 catttttaac aaataagaaa atagagacca gcatcaggat acggatgaag gcagttttgt
    31681 aaaagagaaa actgtaattt tccagagctt cattgaccca ttcgattgaa aaaatctggg
    31741 caatgagttg aatccccata acaaggtaga cctttttgac gattggatta tcaataaaga
    31801 agagaggata ggctaggata tagacagcag tggtcaaaat cgtacaagcg atgcacaaat
    31861 aaaaaagact agaaaaggtt ctgttaagat cttttttgtt atccttgaca ttactgatag
    31921 cccttaaacc gtagttatag acaccataag ttgcaaaggg caagaaaaat gacaaaatag
    31981 tgtcgactga gttgaagtaa ccatagtcag ttcggtccaa gacacgcgcg acataggttc
    32041 cagttaggat gggaaaaata atattcaaga cacgaattcc catgtaagat agagcattta
    32101 attttatact tttcattcaa tttacctcgt ttttcattat atcataaagt tagctaataa
    32161 gaaatgaagg gcagtaagtc aagtaatcac tttgaagttt caaatcttaa gttttaagtt
    32221 ttctttaagg aaagtatatt attctgaagg actctaaaat ttcgcagcca tttattagta
    32281 attgctacag aattcctagt cattactaga aatggactag tttctttgaa taatagaact
    32341 gcataattct cctattctag aaggggagga ccagtatttc ttttatgata ggactagatt
    32401 gtggtataat agagagaata agttttttta gtaagacaaa ggagaaaata gatgatttat
    32461 gcaggaattc ttgccggtgg aactggcaca cgcatgggga tcagtaactt gccaaaacaa
    32521 tttttagagc taggtgatcg acctattttg attcatacaa ttgaaaaatt tgtcttggag
    32581 ccaagtattg aaaaaattgt agttggtgtt catggagact gggtttctca tgcagaagat
    32641 cttgtagata aatatcttcc tctttataag gaacgtatca tcattacaaa gggtggtgct
    32701 gaccgcaata caagtattaa gaaaatcatt gaagccattg atgcttatcg tccgcttact
    32761 ccagaggata tcgttgttac ccacgattct gttcgtccat ttattacact tcgcatgatt
    32821 caggacaata tccaacttgc ccaaaatcat gacgcagtgg acacagtggt agaagcagtt
    32881 gatactatcg ttgaaagtac caatggtcaa tttattacag atattccaaa tcgtgctcac
    32941 ctttatcaag gacaaacacc tcaaacattc cgttgcaagg acttcatgga cctttatgga
    33001 tctctttctg atgaagagaa ggaaatcttg acagatgcat gtaaaatctt tgtgatcaaa
    33061 ggaaaagatg tggccttggc caaaggtgaa tactcaaatc tgaagattac aaccgtaaca
    33121 gatttgaaga ttgcaaaaag tatgattgag aaagactagt aaaatgatta atcaaattta
    33181 tcaactaact aagcctaagt ttatcaatgt caaatatcag gaagaggcta ttgaccaaga
    33241 gaatcatatc cttatccgtc ccaactacat ggctgtctgt catgcggatc agcgttacta
    33301 tcagggaaaa cgtgatccca agattttgaa taaaaagctt ccaatggcaa tgattcacga
    33361 gtcatgtgga accgtcattt ctgacccgac cggaacctac gaggttggtc aaaaagttgt
    33421 catgattccc aatcagtctc ctatgcagag tgatgaagaa ttctatgaaa actacatgac
    33481 agggacccat ttcttgtcta gtggatttga tggctttatg agagagtttg tttctctccc
    33541 taaagatcgt gtggtggctt atgatgctat tgaagatacg gttgcagcca ttacagagtt
    33601 tgtcagtgtg ggcatgcacg ctatgaatcg tctattgact cttgctcata gcaagcggga
    33661 gcggatcgcc gttattggag atggaagttt agcttttgtg gttgccaata ttatcaacta
    33721 tactttgcca gaatcagaga ttgtggttat tggtcgtcat tgggaaaagt tggaactctt
    33781 ctcatttgcc aaagaatgct atattacgga taatattcct gaagagttgg cctttgacca
    33841 tgcttttgaa tgttgtggtg gtgatggtac tggaccagct attaatgact tgattcgcta
    33901 cattcgtcct cagggaacga ttctcatgat gggagttagc gaatataaag tcaatctcaa
    33961 tactcgcgat gccttagaaa agggcttgat tttggttggg tcatctcgtt ctggtcgcat
    34021 tgattttaaa aatgctatcc aaatgatgga agtcaagaaa tttgccaatc gtcttaaaaa
    34081 tatcctttat ctagaagaac ctgtaagaga aattaaagat attcatcgtg tctttgcaac
    34141 cgatttaaac acagccttta aaacagtgtt taagtgggaa gtataagtac tggaggttaa
    34201 ttgtggagaa aatcattaaa gaaaaaattt cttccttact tagtcaagaa gaggaagtcc
    34261 tcagtgttga acaactgggt ggaatgacca atcaaaacta tttggtcaaa acaacaaata
    34321 agcaatacat tgttaaattc tttggtaaag ggacagaaaa gcttatcaat cgacaagatg
    34381 aaaagtacaa tcttgaacta ctaaaggatt taggcttaga tgtaaaaaat tatctttttg
    34441 atattgaagc tggtatcaaa gtaaatgagt atatcgaatc tgcgattacg cttgattcaa
    34501 cgtcaatcaa gaccaagttc gacaaaattg ctccaatatt acaaactatt catacatctg
    34561 ctaaggaatt aagaggagaa tttgctcctt ttgaagaaat caaaaaatac gaatccttgg
    34621 ttgaagaaca aattccttat gccaactatg aatctgttag aaatgcagtc ttctccttag
    34681 agaaaagact ggctgactta ggtgttgaca gaaaatcttg tcatatcgat ttggtgcctg
    34741 aaaactttat cgaatcacct caaggacgac tttatttgat tgactgggaa tattcatcaa
    34801 tgaatgatcc aatgtgggat ttggctgccc tctttttaga gtctgaattc acttcccaag
    34861 aggaagaaac tttcttatct cactatgaga gtgaccaaac accggtttct catgaaaaga
    34921 ttgctattta taaaatttta caagatacta tttggagtct atggactgta tataaggaag
    34981 agcaaggtga agattttggt gactatggtg tgaatcgtta ccaaagagct gttaaaggtt
    35041 tggcttctta tggaggttca gatgaaaagt aaaaacggag ttccttttgg ccttctatca
    35101 ggtattttct ggggcttggg tctaacggtt agtgcttata tcttttcgat ttttacagat
    35161 ttgtcaccct ttgtggtggc tgcagctcat gattttttga gcatctttat cttactagct
    35221 tttctcttgg taaaagaagg gaaagttcgc ctctcaattt tcttaaatat tcgcaatgtc
    35281 agtgttatca tcggagcctt gctagcaggc cctatcggta tgcaggccaa tctttatgca
    35341 gttaagtata tcggaagttc tttagcttca tctgtatcgg ctatttaccc tgcgatttca
    35401 gttctattgg ctttcttctt tttgaagcac aagatttcga aaaatactgt atttgggatt
    35461 gtcttgatta ttggagggat tattgcccag acctataagg ttgaacaggt taattccttc
    35521 tacattggga ttctctgtgc tttggtttgt gctattgcat ggggaagtga gagtgttctt
    35581 agctcctttg ctatggaaag tgaactgagt gaaatcgaag ccctcttaat ccgtcaagtg
    35641 acttcgttct tgtcctatct tgtgattgtg ctcttctctc atcagtcatt tactgcagta
    35701 gccaatggac aattgctagg tctcatgatt gtttttgcag cctttaatat gatttcctac
    35761 ttggcttatt atatcgctat caatcgcttg caaccagcca aggctacagg cttgaacgtg
    35821 agctatgtag tatggacagt cttgtttgca gttgttttct tgggtgcacc gctagatatg
    35881 ctgacaatta tgacgtcact tgtcgtcatt gctggagttt atattattat taaagaataa
    35941 aggagattcg tgtgaaagcc atcatcttag cagcgggatt gggaactcgc ttgcgtccta
    36001 tgactgaaaa tacccctaaa gccttggttc aggttaatca aaaacctttg attgaatacc
    36061 aaattgagtt tctcaaagaa aaaggaatca atgacatcat catcattgtt ggttatctta
    36121 aagaacaatt cgattacttg aaagagaaat acggtgttcg tctcgttttc aatgataaat
    36181 acgctgacta caataacttt tactctctct atcttgtaaa agaagaatta gccaatagtt
    36241 atgttatcga tgccgataac tatctcttta aaaatatgtt ccgcaatgat ttgacacgtt
    36301 ctacttattt tagtgtctat cgtgaagatt gtaccaacga atggttcttg gtctatggag
    36361 atgactacaa ggttcaaaac attattgttg atagcaaggc aggtcgcatc cttagtggtg
    36421 tatccttctg ggatgctcca acagcagaaa agattgtcag ctttatcgat aaggcttatg
    36481 caagcggcga atttgttgat ctctattggg acaatatggt taaggataac atcaaagagc
    36541 tagatgtcta tgttgaagaa ttagaaggca atagcattta tgagattgat agtgtccaag
    36601 actatcataa attagaagaa attcttaaaa acgaaaatta aaagcttcca acatctgaca
    36661 aaatagtcgg atgttttttt gattttttac gaacttttac gaatagatag atgagtagaa
    36721 aaagaaatgg agttatttat gaaaatcaca aactatgaaa tctataagtt aaaaaaatca
    36781 ggtttgacca atcaacagat tttgaaagtt ctagaatacg gtgaaaatgt tgatcaggag
    36841 cttttgttgg gtgatattgc agatatatca ggttgccgta atccagccgt ttttatggaa
    36901 cgttattttc agatagacga tgcgcatttg tcgaaagagt ttcaaaaatt tccatctttc
    36961 tctattttag atgactgtta tccttgggat ttgagtgaaa tatatgatgc gcctgtactt
    37021 ttattttaca agggaaatct tgacctcctg aaattcccga aggtagcggt cgtgggcagt
    37081 cgtgcttgta gcaaacaggg agctaaatca gttgaaaaag tcattcaagg cttggaaaat
    37141 gaactggtta ttgtcagtgg tctggccaag ggcattgaca cagcagctca tatggcagct
    37201 cttcagaatg gcggaaaaac cattgcagtg attggaacag gactggatgt gttttatcct
    37261 aaagccaata aacgcttgca agactacatc ggcaatgacc atctggttct aagtgaatat
    37321 ggacctggcg aacaacctct gaaatttcat tttcctgccc gtaatcgcat cattgctgga
    37381 ctttgtcgtg gtgtgattgt agcagaggct aagatgcgtt caggtagtct cattacgtgt
    37441 gagcgagcaa tggaagaagg acgcgatgtc tttgctattc ctggtagcat tttagatgga
    37501 ctatcagacg gttgccatca tttgattcaa gaaggagcaa aattggtcac cagtgggcaa
    37561 gatgttcttg cggaatttga attttaaaaa tgacctaagc taaaattcta agaaaaaatc
    37621 aattttaaga gaaaatgaac ccaacatttc cataataaaa cgcatattag caagttttta
    37681 acacttgata atatgcgttt tttctaagtg gattagtaga gtagaggatt tttctcatat
    37741 aatactcttc gaaaatctct tcaaactacg tcagcttcca tctgcaacct caaaacagta
    37801 ttttgagctg acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgt
    37861 ggctagcttc ctagtttgcg ctttgatttt cattgagtat aagggaaagt atagtgaatt
    37921 gaaataagat gtgaacaact ctatcaggaa agtcaaatta atttatagaa atattttagc
    37981 agccaaggtg cactgttata gattcaatac actataattt agtgtaattg agaaaggaga
    38041 aatgattgtg attgatgttg gctaggttat gttcaatgat tcctaccgtc tcaaatcttg
    38101 tcagtaagga aaaataaatt cttcaaaagt agagattaca aggtttgttt aagaaagaat
    38161 tcaaagacct tgacaaataa aaataaaatg gttattataa gaaatggtct aaaatagatg
    38221 atgatacttt tcgaaaatct ttttacgtca gctcagcttt gccttgctgt gttttgagca
    38281 agctacggtt agcttccgag tttgattttc atttactaga aatgaaactg atgagagata
    38341 tcagtagaca tttgagtcag gatattatgg aaaatgataa aaagagctcg tgagattggc
    38401 atatcagact actaaagtat tgagtttgtt aggattttag cgactagtta gctgggaaag
    38461 gaagatattt gtgacaaata ataaactgta ttcgttgata gaatttagaa ataaaatata
    38521 tgaagaatta gaactttcca gaagtgattt agcgatttta ctatgtgcca tgcttatcgc
    38581 ctctatcgga ttaaatatgg attcgactcc cgtgattatt ggagccatgt taatctctcc
    38641 tttgatgaca cctattctgg gagtggggct ctctctagct atatttgatt ttaaattgtt
    38701 aagaaaatct tttaaaatat tagctattca aattcttgcc agtctaatag cttcaacact
    38761 ttatttttat ctttctccca tttcgtatgc tagttcggag attgttgcta gaacctctcc
    38821 gactatttgg gatgttctca ttgcttttgt aggagggata gcaggtatta ttggtgctag
    38881 gaaaaaagag accaataata ttgttcctgg tgttgctatt gcaaccgcct tgatgcctcc
    38941 tctttgtaca gtaggttatg ctattgcttc tgctaatcta aaatttatca taggctcctc
    39001 ttacctattc ctcatcaatt gtagctttat tgtcattgcg acttatatag gtgttaggtt
    39061 gatgatggtt aagaaacatt attttaaaga taatgaagaa gactctaaaa tgcgtaggat
    39121 tttgcttcta gttgctgttt tgctgatgat tccgagtttc atctctgcaa cgactttagt
    39181 gagagaaacg ttgaaaaaag agtcccttaa gaaatttata tcagagcagt ttcaggggca
    39241 taatattttg aaaaaaacct attctaaaaa gactcatacc ctaaagctaa ccatctcagg
    39301 aaattatttg acagaagaag aactcgatat gatttcaagt aagagaggtg actatggttt
    39361 aagtgatgtt tctgttcaag tttcacaatt gtctgattca gaacaactta gtaaggaaga
    39421 gctggtggag tatttcttcc agtatatcaa ggataaggaa gcaaaagaaa aggagaaagc
    39481 taataaattt gatacagagt ctgaggagca ataatttctt gagaatagct ggtttctctc
    39541 gtgagtcttc tatgtatatc aaaggaagac tgaggtttta agtataaaac ttttcttcta
    39601 ttatagtagc taagtcttga cagggttcaa aaaatggttt acactttata aagtttatta
    39661 ctttgaaaag gtgtgatact gtggctacgg caacaaaaaa gaaaaaatca acagttaaaa
    39721 aaaatctagt catcgtggag tcgcctgcta aggccaagac gattgaaaaa tatctaggca
    39781 gaaactacaa ggttttagcc agtgtcgggc atatccgtga tttgaagaaa tccagtatgt
    39841 ccgtcgatat tgaaaataat tatgaaccgc aatatattaa tatccgagga aaaggccctc
    39901 ttatcaatga cttgaaaaaa gaagctaaaa aagctaataa agtttttctc gcgagtgacc
    39961 cggaccgtga aggagaagcg atttcttggc atttggccca tattctcaac ttggatgaaa
    40021 atgatgccaa ccgtgtggtc ttcaatgaaa tcaccaagga tgcagtcaaa aatgctttta
    40081 aagaacctcg taagatagat atggacttgg tcgatgccca acaagctcgt cggatcttgg
    40141 atcgcttggt agggtattcg atttcgccta ttttgtggaa gaaggtcaag aagggcttgt
    40201 cagcaggtcg cgttcagtcc attgccctta aactcatcat tgaccgtgaa aatgaaatca
    40261 atgccttcca gccagaagaa tactggacag ttgatgctgt ctttaaaaag ggaaccaaac
    40321 aatttcatgc ttccttctat ggagtagatg gtaaaaagat gaaactgacc agcaatgatg
    40381 aagtcaagga agtcttgtct cgtctgacga gtaaagactt ttcagtagat caggtggata
    40441 agaaagagcg caagcgcaat gctcctttac cctataccac ttcatctatg cagatggatg
    40501 ctgccaataa aatcaatttc cgtactcgaa aaaccatgat ggttgcccaa cagctctatg
    40561 aaggaattaa tatcggttct ggtgttcaag gtttgattac ctatatgcgt accgattcga
    40621 ctcgtatcag tcctgtagcg caaaatgagg cggcaagctt cattacggat cgttttggta
    40681 gtaagtattc taagcacggt agcaaggtca aaaacgcatc aggtgctcag gatgcccatg
    40741 aggctattcg tccgtcaagt gtctttaata caccagaaag catcgctaag tatctggaca
    40801 aggatcagct caagctatat acccttatct ggaatcgttt tgtggctagc cagatgacag
    40861 cggccgtttt tgataccatg gctgttaaat tgtctcaaaa aggggttcaa tttgctgcca
    40921 atggtagtca ggttaagttt gatggttatc ttgccattta taatgattct gacaagaata
    40981 aaatgctacc agatatggct gttggagatg tggtcaaaca ggttaatagc aaaccagagc
    41041 aacatttcac ccaaccgcct gcccgttatt ctgaagcaac actgattaaa accttagagg
    41101 aaaatggggt tggacgtcca tcaacctatg cgccaaccat tgaaaccatt cagaaacgtt
    41161 attatgttcg cctggcagcc aaacgttttg aaccgacaga gttgggagaa attgtcaata
    41221 agctcatcgt tgaatatttc ccagatatcg taaacgtgac cttcacagct gaaatggaag
    41281 gtaaactgga tgatgtcgaa gttggaaaag agcagtggcg acgggtcatt gatgcctttt
    41341 acaaaccatt ctctaaagaa gttgccaagg ctgaagaaga aatggaaaaa atccagatta
    41401 aggatgaacc agctggattt gactgtgaag tgtgtggcag tccaatggtc attaaacttg
    41461 gtcgttttgg taaattctac gcttgtagca atttcccaga ttgccgtcat acccaagcaa
    41521 tcgtgaaaga gattggtgtt gagtgtccaa gctgtcatca gggacaaatt attgagcgaa
    41581 aaaccaagcg taatcgcctt ttctatggtt gcaatcgcta tccagaatgt gaatttacct
    41641 cttgggacaa gcctgttggt cgtgactgtc caaaatgtgg caacttcctc atggagaaaa
    41701 aagtccgtgg tggtggcaag caggttgttt gtagcaaagg cgactacgag gaagaaaaga
    41761 ttaaataaga ggaggggccc gaaagtaaat ttcaggctcc ttttggttag aacttgacaa
    41821 aatacatcat tttatgcgaa actagaagaa gattatttta actaggagaa gttatgcgtc
    41881 ttatctatct gataattggt tttttatcac tggccttggc tattgttggg gttgttttac
    41941 ccttgttgcc gacaacgcct ttccttttgt tgtctattgc ttgtttctcc agaagttcca
    42001 agcgtttcga agactggctt tatcatacca agctctatca aacatatgta gctgattttc
    42061 gcgagactaa gtctattacg cgtgaacgaa agaaaaaaat catcgtctct atctacgtct
    42121 tgatgggaat ttctatttat tttgcacctc ttttaccagt caaaatcggt ctgggtgctt
    42181 tgaccatctt tatcacttat tatcttttca aggtcattcc agacaaagaa tagttaaaac
    42241 agtagttatt tgccttgata aaattgaaag catattcata ataatatgat ataataaatt
    42301 tgaagtaata ttcaaggaga atcaaatgat ttacgaattt tgtgctgaaa atgtgacttt
    42361 acttgaaaaa gcgatgcagg ctggagctcg tcggattgaa ctctgtgata atctagcagt
    42421 tggtgggaca acacccagct atggagtgac taaggcagcg gttgaactgg cagctaacta
    42481 cgatacaacc atcatgacca tgattcggcc acgtggtggt gactttgtct ataatgacct
    42541 agaaattgct atcatgctag aagacattcg tttgactgct caggctggaa gtcaaggggt
    42601 tgtatttgga actttaactg ctgataaaaa gttggataag cctaatctgg aaaagttaat
    42661 tgctgcatca aaaggaatgg aaattgtctt tcacatggcc tttgatgaac taagtgatga
    42721 agatcaaccg gaagctattg actggctcag tcaagccggt gtcactcgta tcctaactcg
    42781 tgctggtgtg tctggcgact ccttagaaaa acgttttgtt cactatcaca gaattttgga
    42841 gtacgctaaa ggtaaaattg aaattctacc aggtgggggg attgaccttg aaaaccgtca
    42901 aacctttatc gaccaggtgg gggtaacaca attgcatggt actaaggttg ttttttaaaa
    42961 aatagaaagg aactgctagc tttgggtagc agttttcact tatgtttgaa atttttaaat
    43021 cctatcaatt taatcaagaa aaggctcatg attatggttt tatagaaaat agcgaagtct
    43081 ggacatatag ttgccagatt ttgcaaggtg actttgtcat gactgtgtcc atcactgctg
    43141 ataatgtgaa ctttcaagtc tttgaccaag agactggtga cctctatcct cacgttcata
    43201 tggaaagcat gaggggaagt tttgtcggaa atgtccgtga ggcttgtctg gagattcttt
    43261 accagattcg gaaggcttgt tttgatgtgc aagattttat ctgtcatcag actaagcgta
    43321 tcatgactca agttcaggaa aagtatggaa accagttgga gtatctgtgg gaaaaatcgc
    43381 ctgatacagc tgtattgcgc catgaaggca atcaaaagtg gtatgccgtc ttgatgaaaa
    43441 tctcttggaa taagctggaa aagggcagag aaggacaagt ggaagcagtc aacctcaagc
    43501 atgaccaagt agctaatttg ctttcacaaa aggggattta tccagccttc catatgagca
    43561 agcgctactg gattagtgtg tcccttgatg atactttatc agatgaagaa gtactggaat
    43621 tgatagaaaa aagttggaac ttaacctcta aaaaatgaaa tattttaata attttcatga
    43681 actttcaatt agctgaatat tctttactga agaaattttc agaaaatata ggatttacca
    43741 caccagagga atgtggtgcc atcttcaaat acctgattga gaatgtcaag acggatcgtc
    43801 agatcatcta ttcgcctcac tgtcatgatg acctcggaat ggcagtggca aatagccttg
    43861 ctgctgtcaa gaatggtgca ggacgtgttg aagggactat caatggtatt agggagcgag
    43921 ctgaaaatgc tgctttggaa gaaattgcag tggctctcaa tattcgccaa gattactacc
    43981 aagtagaaac cagtattgtc ctaaatgaga ccatcaatac gtcagaaatg gtttctcgct
    44041 tctctggtat tccagttcct aaaaacaaag ccgtcgttgg tggcaatacc ttctcccacg
    44101 aatctggtat tcaccaagat ggagtcctta aaaatcctct cacttatgag atcatcacac
    44161 ctgaattggt tggtgttaag attccgcttg gaaaattatc tggtcgccat gcttttgttg
    44221 agaaactgag agaattggcc ctagatttta cagaagagga tatcaaacca ctctttgcta
    44281 agttcaaggc actggccgat aagaagtaag aaatcacaga tgcagatact cgagctttgg
    44341 tagctggaac catggttgaa aatccagaag gcttccactt tgatgattta caacttcaaa
    44401 ctcatgcaga taatgacatt gaagcgctcg ttagcctagc caatatggat ggtgagaaag
    44461 tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat ctttaatgct atcgataagt
    44521 tctttaacca atctgttcgt ttggtgtcct acactatcga tgcggtaaca gatggaatcg
    44581 atacccagga tcgggttttg gtcactgttg aaaacagaga tacagaaacc atctttaatg
    44641 cagcagggct tgattttgat gtgttgaagg cttctgctat tgtctatata aacgctaata
    44701 cctttgttca aaaagagaat gcaggtgaga tgggacgcag tgtttcttac cacgatatgc
    44761 ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta gctctagcag gagacggaat
    44821 tggcccagaa atcatggagg ttggtttaga agttctggag gctctagctg aaaaaacagg
    44881 ttttgactat gagattgaca gacgaccgtt cggaggtgca gatattgatg cagcaggacc
    44941 tcccttacct gatgaaaccc ttaaggcaag tagggaagca gatgctatcc tactagcagc
    45001 tatcggtagt cctcagtatg atggagcagt ggttcgccct gaacagggcc tgatggctct
    45061 ccgtaaggaa ctcaatcttt acgctaatat tcgtcctgta aaaatctttg acagtctcaa
    45121 gtatttgtca ccactcaaac tggaacgaat tgctggtgta gactttgtcg tggtgcgtga
    45181 attgacaggc gggatttact ttggagatca tattcttgaa gagcgcaatg cgcgtgatat
    45241 caacgactat agctatgagg aagtggagcg gattattcgc aaagcctttg aaattgcaag
    45301 aaatcgcaga aaaatcctta ctagtatcga taagcaaaat gttctagcga cctcaaaact
    45361 ctggcggaaa gtagctgagg aagtcgcaca ggatttccca gatgtaacct tggaacacca
    45421 gctggtagac tcagctgcta tgcttatgat taccaatcct gctaagtttg atgttattgt
    45481 aacggagaat ctttttggag atattttatc tgatgaatca agcgtcttat ctggtacact
    45541 tgaggttatg ccatcagcca gtcattctga aaatggacca agtctctatg aacctattca
    45601 cggttcagca cctgatattg caggtcaagg aattgccaat cctacttcca tgattttatc
    45661 agttgccatg atgttgagag atagtttcgg acgttatgag gatgcagagc gtatcaaacg
    45721 tgctgttgag acaagtctgg cggcaggaat tttaacgaga gatataggag gtcaggcttc
    45781 aacaaaggaa atgacggaag ctattattgc aaggttatga agttagacga aaaaattact
    45841 ctagtccttt tgatttggaa tgtcatcatt ttcttgattt atggcattga caaattcaag
    45901 gcaagaagaa gagcttggcg catcccagag aaaatcttac tcattttagc ccttacttgt
    45961 ggtggttttg gggcctggtt agctggaatt acttttcacc acaagactcg aaaatggtac
    46021 tttaaaacag tttggtttct tgggatggtg accacactag tagccttata ttttatttgg
    46081 aggtaatgga tggcagggtc ttcgagggaa cacgctgctt gggctctagc ggactatggt
    46141 tttaaggtcg tgattgcagg atctttcggt gacattcatt acaataatga actcaataat
    46201 ggcctgttgc caatcgttca gcctagagag gttagagaga aattagccca gctaaaacca
    46261 accgaccagg taactgtgga cttggaacaa caaaaaatca tctcaccagt tgaagaattc
    46321 accttcgaga tagatagcga gtggaaacat aaactcctaa atagtttgga tgatatcggt
    46381 attaccttgc agtatgaaga gttgattgtt gcttatgaaa aacaacgacc agcctactgg
    46441 caggattaga aaaaatagaa aaggaaatat agtaaactga aataagatgt aaacaaatga
    46501 attagagctt aacatccatt tccagcaatt ttttagaaac tacagtggac tattctggat
    46561 tcaacacatt ataaaattat gacaaaacac attcacaaga aggctacgac attttaaaag
    46621 gtgagggcgg atgtatcgtt tgccctacta aagttggtta cattatcatg accagcaaca
    46681 aggcaggact tgagcgtaag ttcgcagcca aagaacgtaa gcgtaacaaa ccaggtgttg
    46741 ttctctgcgg tagcatggat gaactttgcg ctttagcgca actcaaccca gaaattgaag
    46801 cattctacta aaaacattgg gatgaagata ttcttcttgg ttgtatcctt ccttggaaac
    46861 cagaagtctt tgaaaaactc aaagcatacg gggatggccg tgaagaactt atgactgatg
    46921 tacgtggtac tagctgtttt gttatcaagt ttggaaaagc aggtgaacaa ttggctgcca
    46981 agctttggga agaaggtaaa atggtctacg cctcatctac ttcaatgaca aaacgattga
    47041 aactcgctat gagagcaagg tgtaatggtg tctatggtcg ataaggacgg caaactcatc
    47101 ccagaacaag gaggagcacg ttcaacctca ccagcaccag ttgtgatccg taaagggctt
    47161 gacattgata aaatcatgat gcacctgtca gatactttta actcatggga ctaccgtcag
    47221 gttgagtatt attaggatag agaagaagtc tagtgttaag gacattacag ctcataatac
    47281 taggcttttt tatagaaatt cttttctttt tctataggat atggtattct atgtagaaaa
    47341 tatatgttaa taagtaatgc caatatttaa acatcattag taaaaggagt tagattgatg
    47401 aataaaagaa aagttagttt agaagatttt tataaatggt atagtctaaa taaagaagag
    47461 ttattaaata aggcaactgt tggtgaaaag tttaatgata aattaaaaga agagtttctc
    47521 caggaatggc ctttggatag gattttaaca atgtcaatcg atgaatatgt aataggaaag
    47581 ggacagcaaa ataagtcttt atgctacgct cttgagaagg gaaaatacaa aaatctattt
    47641 cttggaattt ctggtggctc agcttcaaaa tttggtattt attggaataa aaaaacaaac
    47701 aaatataaag atcaagctaa taatgagatt tcagagttgg atcagcgatt ttcaaaatta
    47761 aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt ttaactttga aaatcctatt
    47821 tttgatatga aaagatcaac aaatgaattt attggtcgtt ctgctatggt gacaaaatta
    47881 ctttgtatct attctggggg agatcctttc tttggtgtaa atattaatag tcagaaagaa
    47941 ttttggaacc actttgtttc tcagacaaat caaggtggac cttatctgca aaatcataaa
    48001 ataattgaac tggtgtccaa aacttatcct gagttggagc catcgaaatt aggaactatg
    48061 ctttttgagt attctaagct ttttatggaa aataaggaag acaatagtac aatggattca
    48121 tcaaacaatt ttcgtcatca attaactcaa tctctattaa agtctccaaa ccttatcctt
    48181 cgtggtgctc ctggcacagg aaagacttat cttgctaaag aaattgccaa agaattaacg
    48241 gatggcaacg aagaccaaat cggatttgta caatttcacc catcctatga ttatacggat
    48301 tttgtagaag gtttaagacc agtatcaaat ggggatggag ctattgagtt taggctacag
    48361 gacggtattt ttaaagattt ttgtcagaaa gcaaaagaaa cccaattgat tggaggacaa
    48421 gataattttg atgaggcttg ggattcttac ttagaatata taaatgttgc tgaagaaaaa
    48481 gaatatataa caaaaacatc ttacttatct gttaatagta gacaaaattt gtcagtaaat
    48541 tatgatagtg gtgttccagg atggtcacta cctagcaaat atgtttacga gttgtataaa
    48601 gataaaaatt ataataagca agaatactac aaaagtggtg gaaaaactgt cctagaaaca
    48661 ttgagaaaga gatttggttt gaaagactat gtttccccaa cagaaattga tactgataag
    48721 aaattcgtct tcatcatcga tgaaatcaat cgtggggaga tttctaagat ttttggcgaa
    48781 ctctttttct ctatcgaccc tggctatcgt ggtgaaaaag gaagtgtttc tacccaatat
    48841 gcaaatctac acgaaactga tgaaaagttc tatatccccg aaaatgttta catcatcgga
    48901 actatgaatg atattgatcg ttcagtggat acctttgatt ttgctatgcg tcgtcgtttt
    48961 cgttttgttg aagttactgc cgagggtcaa gttggcatgt tggataaaga gctgaatatc
    49021 catgcagaag aagcaaaaat tcgtctaaga aacttgaacg ctgctatcga aaatgttcag
    49081 gaattaaaca gtcattatca tattggacca agttattttc ttaagttgaa ggatgtagat
    49141 tttgactatg aattactctg gtccgattat attaagcctc tcctagaaga ctacttgcga
    49201 ggttcttatg atgaggttga aactttggaa actttgaaaa aagcatttga actgacaaat
    49261 aatgatcaaa ctggtcaaca agatactggt gataatgatg cggattactg ataatcaata
    49321 caagattatt aaagaaaaat ttgttgaaga atatccgaaa ctaagcaatc ttcttttaga
    49381 cagaaccttg gaaagtctat cccaagatga acgtattttc atttttccaa atgatttgac
    49441 tcatactcct gatttggata aggaccaaaa gatttttgaa acagtcaatc agaaaatcaa
    49501 gacagggaac gtgattggtt ttcttggata tggtcaggaa agattaacga tttcctcacg
    49561 attttctgat gagagtaatg accatttttt gcattatctc ttaaacaagg ttcttcatat
    49621 caatctcact agtttagatg ttgctttgtc tcgtgaagag aggctttatc aacttttgat
    49681 gtatctcttc cccaagtatc tacaagctgc tattcgaaaa ggtctttata aggaatacca
    49741 gagattttct cataacgaca gtcatgttaa gggagtgatt gatgtaagaa accatctcaa
    49801 gaaaaatctt cctttcacgg gaaatattgc ctacacaacg agagagttca cctatgataa
    49861 tcccctcatg cagttggtcc gtcacactat tgaatacatt aagaatcaga aaagcattgg
    49921 tcaaggggta ctagataatc tctcaactag tcgtgaaaac gtatctgaaa tcgtgcgtgt
    49981 aacgccctct tataaactag ctgatcgtgc taagattatt cggggaaatc aatctaaacc
    50041 tatacgtcat gcatactttc acgagtacag aaacttacaa gaactttgtc tgatgatcct
    50101 aaaccaagaa aagcacggtt tagggtatca agatcaaaaa atctatggta ttctctttga
    50161 tgttgcctgg ctttgggaag agtatgttta caccttgttg ccaaaaggtt ttgtacatcc
    50221 cagaaataag gataagacgg atggaatttc agtattttct gttgggaaac gaaaagtata
    50281 tccagatttt tatgacagag aacgaaagat tgttctagat gcaaaatata aaaaactgga
    50341 attgactgaa aaaggaatca accgtgagga cttattccag ctgatttcct attcttatat
    50401 tttaaaagct gagaaggctg gactgatttt tcctagtatg gagcagtcag taaatagtga
    50461 aataggaaaa gtagctggct atggagctca attgaagaag tggtctattc gaatccctca
    50521 gaatgcctca ttctatagta cattttgtaa aatgatggaa aattcagaag aaaattttaa
    50581 agcgattatt gatgaagaag tggggagaaa ataatttccc ctctttcttt tatttttaac
    50641 acaagtaaaa cccgaacgat atattttaat tcataaaata atttgacaaa aactgtactt
    50701 tggtttataa taaattaagg aaacgtcgga aaaggcgtag tgatgcaaga gcataggtag
    50761 gtcattacaa aagaaacgag acatcgatat gttaaatgaa tttccaattt ttgattacga
    50821 agatattcaa ttgattccaa ataaatgtgt cattaaaagc cgtgcagaag cggatacaag
    50881 tgtcacttta ggaaatcaca cctttaaact acctgttgtg ccagcgaata tgcagacgat
    50941 tttggatgaa aatgtagcag agcaactggc taaaggtggt tacttctaca ttatgcaccg
    51001 ttttgatgag gcaggacgca ttccttttat taaacgaatg cacgatcaag ggctcattgc
    51061 ttctatctct gtcggtgtta aggattatga gtatgatttc gttagacagc tcaaagctga
    51121 tgctcctgag tatatcacta ttgatattgc tcatggtcat gcggatagcg tgatttctat
    51181 gattcaacac atcaagaaag aattgccaga tacctttgtc attgctggaa atgtgggaac
    51241 accagaagct gtgcgtgaat tggaaaatgc tggtgcggat gctactaagg tcggaatcgg
    51301 tcctggtaag gtttgtatca ccaaggttaa gactggtttt ggtacaggtg gttggcagtt
    51361 ggctgctcta cgctggtgtg ccaaggctgc gcgtaaaccg attatcgctg atggaggaat
    51421 tcgtactcac ggtgatattg ctaagtctat ccgcttcggt gctagcatga tcatgattgg
    51481 ttccctcttt gcaggacaca ttgaaagtcc agggaaaacg attgaagtcg atggtgaaca
    51541 gttcaaagaa tattatggtt cagcctcaca atatcaaaaa ggtgcttaca aaaatgtgga
    51601 aggcaaacgt atcttgcttc ctgctaaagg tcatctgcaa gacactttaa ctgagatgga
    51661 acaagacctt caaagtgcta tttcttatgc aggtggacgt caggttgctg accttaaaca
    51721 cgttgattat gtgatcgtga aaaactccat ctggaatggg gatgcttccc actaagacgg
    51781 ggtctttgac caaaaaactt gttattagag caaatttctg ttataataaa acaagtttcc
    51841 acccttagtg taatggatat cacgtaagat tccggttctt gagatggggg ttcgattccc
    51901 tcagggtgga tgtaaacatc ctaaaaagcc tttaataggg cttttttctt tatcctgacc
    51961 caaatttgcc gctaaaactg agaatctctg tctaaagaat tcccaaatgc tttccagtcc
    52021 cgttttagag tgactcaggg ggcttttttt gatataataa aaaggactat tatcagttag
    52081 aaagaggttg gtatgaaaga attacaaact gtactaaaga atcattttgc aatcgaattt
    52141 gcagacaaaa atttactgga aactgccttt actcatacga gttatgccaa tgagcaccgc
    52201 ctcttaaaaa tttcacacaa tgaacgcttg gaatttttag gagacgctgt tctacagtta
    52261 ttgatttcag aatatctata taaaaaatat cctaaaaagc ctgaaggtga cctatcaaaa
    52321 ctccgtgcta tgattgtccg tgaggagagt ttagctggtt ttgcgcgtga ttgccagttt
    52381 aaccagttta tcaagttggg taaaggggaa gaaaaatcag gtggtcgcaa tcgtgacacc
    52441 attcttggtg atgcctttga agcctttctt ggtgcccttc ttttggataa ggatgtggcc
    52501 aaggtcaagg aatttatcta tcaagtcatc attcctaagg ttgaagcagg cgagtttgag
    52561 atgattacag actataaaac ccatctccaa gagttgcttc aggtcaatgg tgatgtggct
    52621 attcgttatc aggtgatttc tgaaacaggg cctgctcatg ataaggtctt tgatgtagaa
    52681 gttcttgttg aaggtaagag catcggtcaa ggccaaggtc gttctaagaa attagcagag
    52741 caggaagctg ccaaaaatgc cgttgagaag gggctggatt catgtattta aaggaaatcg
    52801 aaattcaggg gttcaagtct tttgctgata agaccaaggt cgtttttgac caaggtgtga
    52861 cggcagttgt tggacccaat ggatctggaa agtccaatat tacagaaagt ctgcgttggg
    52921 ctttggggga gtctagtgtc aagagtctcc gtgggggcaa gatgccggat gtcatctttg
    52981 ctggaaccga aagtcgcaaa ccgctcaatt atgcttctgt agttgtgact ctggataatc
    53041 atgacggatt tatcaaggat gcaggtcaag aaatcagggt ggaacgccat atctatcgta
    53101 gtggagatag cgaatacaag attgacggca agaaagtccg tctgcgtgat attcatgacc
    53161 tcttcttgga tactggattg ggacgagatt ccttctctat tatttcccaa gggaaggttg
    53221 aggagatttt taattccaag cctgaggaac gacgagctat ttttgaagaa gctgctggag
    53281 ttttaaaata caagactcgc agaaaagaaa ccgagagtaa actgcagcaa actcaggata
    53341 atctggaccg cttagaggac attatctacg agttggataa tcaaatcaag cctcttgaga
    53401 agcaagctga gaatgcccgt aagtttttag acttggaagg acaacgtaag gctatttatt
    53461 tagacgttct ggttgctcaa atcaaggaaa ataaggctga actagagtcg acagaagaag
    53521 agttgactca ggttcaagaa ctcttgatga gttattacca aaagcgtgaa aaattagaag
    53581 aagaaaatca aactcttaaa aagcaacgcc aagatttaca ggctgaaatg gccaaagacc
    53641 aaggcagttt gatggacttg actagtctga ttagtgattt agaaagaaaa ttagccctat
    53701 cgaaactgga gtccgagcaa gtggccttga atcaacagga ggcacaagcc cgtttggctg
    53761 ctttggagga taagagaaat tcactcagca aagaaaagtc tgataaagaa agctctttag
    53821 ctctgttaga gggaaatcta gtccaaaata atcaaaaact caatcgttta gaagctgaat
    53881 tgctggcttt ttcagatgat cctgatcaga tgattgagct tttgcgtgaa cgctttgtgg
    53941 cgcttttaca agaagaagcg gatgtctcaa accaactgac ccgcatcgag aatgagttgg
    54001 aaaatagtcg tcagctttct caaaaacaag cagatcaact agaaaagctg aaagagcaat
    54061 tggctatagc taaagagaag gctagtcagc aaaaggaaga gcttgaaact gccaaggagc
    54121 aggttcagaa attattggct gactatcaag ctattgccaa ggagcaagag gagcaaaaaa
    54181 cttcctatca agctcaacaa agtcaactct ttgaccgtct ggatagtctt aaaaacaagc
    54241 aggctagagc tcaaagtttg gaaaacatcc ttagaaatca cagtaacttt tatgcaggtg
    54301 taaagagtgt tctccaagaa aaagaccgcc ttggtgggat tattggtgct gttagtgagc
    54361 atttgacctt tgatgtgcat tatcaaactg ccttagagat tgcacttgga gccagcagtc
    54421 agcatatcat cgtagaagat gaagagtcgg caaccaaagc tattgatttc cttaaacgaa
    54481 acagagccgg tcgtgcaacc ttccttccgt tgacaacaat caaggctcgt acgatttcta
    54541 gccagaatca agatgttatc gctgtaagcc caggtttcct tgggatggca gatgagttgg
    54601 tgacttttga tactagactg gaagccattt tcaagaattt gctagctacg acggctattt
    54661 ttgatactgt agagcatgcg cgtgcagcag ctcgccaagt tcgttatcag gttcgtatgg
    54721 tgacattgga tgggacagaa ttacgcacgg gtggttccta tgcgggtggt gccaatcgcc
    54781 aaaataacag tattttcatc aagccagaac tggagcaatt acaaaaagaa attgctgcag
    54841 atgaagcaag cttgggttca gaagaagcgg ctttgaagac cttgcaagac cagatggcta
    54901 cattgacaga aagattagaa gccatcaaat ctcaaggaga acaggcacgt attcaggagc
    54961 aaggcttgtc cctcgcttat cagcaaacta gtcagcaagt tgaagaactg gaaactcttt
    55021 ggaaactcca agaagaggaa aaagatcgtc tttctgatgg agattggcaa gcagacaagg
    55081 aaaactgcca agagcgtctt gctgcaatcg ccagtgacaa gcaaaatctg gaagctgaga
    55141 ttgaagagat taagtctaat aaaaatgcca tccaagaacg ctatcaaaac ttgcaggaag
    55201 agctagcgca agctcgtttg cttaagacag aactgcaagg gcaaaaacgt tatgaagtgg
    55261 ctgatattga acgcttaggc aaggaattgg acaatcttga ttttgaacaa gaggaaatcc
    55321 agcgccttct tcaagaaaag gttgacaatc ttgagaaggt tgatacagaa ttgctcagtc
    55381 aacaggcgga agaatccaaa actcagaaaa cgaacttcca acaaggtttg attcgcaaac
    55441 agtttgagtt ggatgatata gaaggtcagc tggatgatat tgctagtcat ttggatcagg
    55501 ctcgccagca gaatgaggag tggattcgca agcaaacacg tgctgaagcc aagaaagaaa
    55561 aggtcagcga gcgcttgcgc catctacaaa gtcaattaac agaccagtac cagattagct
    55621 atactgaagc tctagaaaaa gcgcatgaat tggaaaacct caatctggca gagcaagaag
    55681 ttaaggattt agagaaggct attcgctcac tgggtcctgt caatatagaa gctattgacc
    55741 agtacgaaga agttcacagc cgtctggatt tcctcaatag ccagcgagat gacattttgt
    55801 cagcgaaaaa tctgcttctt gagactatta cagagatgaa tgatgaggtc aaggaacgct
    55861 ttaaatcaac ctttgaagct atccgtgagt cctttaaagt gaccttcaag cagatgtttg
    55921 gcggaggtca agcggacctg attttgactg agggagactt gctgacagct ggggttgaga
    55981 tttctgttca acctcaaggt aagaaaatcc agtcccttaa tctcatgagt ggtggtgaaa
    56041 aagctctatc ggctcttgcc ttgctcttct ccattattcg tgtcaagact attccatttg
    56101 ttatcttgga tgaggtggaa gctgcgctgg atgaagccaa tgttaaacgt tttggggatt
    56161 acctcaaccg ctttgacaag gacagccagt ttatcgtcgt aacccaccgt aagggaacca
    56221 tggcagcggc tgattccatc tatggagtga ccatgcaaga atcgggtgtt tcaaagattg
    56281 tttcagttaa gttaaaagat ttagaaagta ttgaaggatg acaattaaac tagtagcaac
    56341 ggatatggac ggaaccttcc tagatgggaa tggacgcttt gatatggatc gtctcaagtc
    56401 tctcttggct tcctacaagg aaaaagggat ttactttgcg gtggcttcgg gtcggggatt
    56461 tctgtctctg gaaaaattat ttgctgatgt tcgtgatgac attattttca tcgcggaaaa
    56521 tggcagtttg gtagagtatc aaggtcagga cttgtatgaa gcgactatgt ctcgtgactt
    56581 ttatctggca acttttgaaa agctgaaaac gtcaccttat gtagatatca ataaactgct
    56641 cttgacgggt aagaaggggt catatgttct agatacggtt gatgagacct atttgaaagt
    56701 gagtcagcat tataatgaaa atatccaaaa agtagcgagt ttggaagata tcacagatga
    56761 cattttcaaa tttacaacca acttcacaga agaaacgtta gaagctggtg aagcttgggt
    56821 caatgataat gtccctggtg tcaaggctat gacaactggc tttgaatcta ttgatattgt
    56881 tctggactat gtcgataagg gtgtagctat tgttgaatta gctaaaaaac ttggtatcac
    56941 aatggatcag gtcatggctt ttggagacaa tcttaatgac ttacatatga tgcaggttgt
    57001 gggacatcct gtagctcctg aaaatgcacg acctgaaatt ttagaattag caaagactgt
    57061 gattggtcac cataaggaac ggtcggttat agcttatatg gagggcttat aatggcagat
    57121 ataaaattga ttgcattgga cttggacggg accttgctga ctactgataa aaggctgacg
    57181 gatcgtacca agtcaacctt gaaagctgcg cgtgatcgtg gtatcaaggt cgtattgaca
    57241 actggtcgtc ccttaaaagc catggatttc tttctccatg agttagggac tgacggtcag
    57301 gaagatgagt ataccattac ttttaatggt ggattagttc agaaaaatac aggagaaatc
    57361 cttgataaaa cagtcttttc atatgatgat gtggcacgtt tgtatgaaga aacagagaaa
    57421 ttatcactgc ctcttgatgc catctcagaa ggaacagttt atcaaatcca atcggaccaa
    57481 gaaagtcttt atgccaaatt caatccagct ttgacttttg ttccagttga ctttgaagac
    57541 ctgtctagtc aaatgaccta caacaaatgc gtgaccgcct ttgctcaaga acccttggat
    57601 gcagccattc agaagatttc tctagaattg tttgaccaat atgaaatctt taaatcacgt
    57661 gaaatgttgc tagaatggtc accaaagaat gttcataaag caacaggttt ggcaaaacta
    57721 atcagccatc ttggaatcga ccaaagccaa gtgatggctt gtggtgacga ggccaacgac
    57781 ctctctatga ttgaatgggc aggtcttggt gttgctatgc aaaacgctgt tcctgaagta
    57841 aaggtagccg caaatgtagt gacgccgatg accaacgatg aggaagctgt cgcctgggct
    57901 atcgaagaat atgtgctaaa ggagaactaa gatatgggat tgtttgaccg tttattcgga
    57961 aaaaaagaag aacctaaaat cgaagaagtt gtaaaagaag ctctggaaaa tcttgatttg
    58021 tctgaagatg ttgatcttac cttcacagaa gctgatgaag ttcctcagga agaagcagag
    58081 gttgaaattg ttgaacaagc tgtgttccaa gaagaggaaa tccaagacac agttgaagaa
    58141 agtcaggatt cagagccagc tgtaggggtt tctcaagaag aaatagaaga attaccaaac
    58201 tcagaagaat taccagagga agagaagctt gagcacgaag gaactgtaga agaaaataat
    58261 tctgaagtgc ttgaaccaga agctcctcaa acagaagaaa ctgttcagga aaaatatgac
    58321 cgcagtctta agaaaactcg cacaggtttc ggtgcccgct tgaatgcctt ctttgctaac
    58381 ttccgctctg ttgacgaaga atttttcgag gaactggaag aactgctgat tatgagtgat
    58441 gttggtgtcc aagtcgcttc taacttaacg gaggaactac gttacgaagc caagcttgaa
    58501 aatgccaaga aacctgatgt acttcgtcgt gtcatcattg agaaattggt tgagctttat
    58561 gaaaaggatg gtagctacga tgaaagcatc cacttccaag ataacttgac agttatgctc
    58621 tttgttggtg tgaatggtgt tgggaaaaca acttctatcg gaaaactagc ccaccgctac
    58681 aaacaagctg gtaagaaggt catgctggtt gcagcagata ccttccgtgc gggtgcagta
    58741 gctcagctag ctgaatgggg ccgacgagta gatgttccag tagtaactgg acctgaaaaa
    58801 gctgatccag ccagcgtggt ctttgatggt atggaacgtg ccgtggctga aggtatcgat
    58861 attctcatga ttgatactgc tggtcgtctg caaaataagg ataaccttat ggctgagttg
    58921 gaaaagattg gtcgtattat caaacgtgtt gtgccagaag caccacatga aaccttcttg
    58981 gcacttgatg catcaacagg tcaaaatgcc ctagtacagg ccaaagaatt ttcgaaaatc
    59041 acacctttaa cgggaattgt tttgactaag attgatggaa ctgctcgagg aggtgtggtt
    59101 ctagccattc gtgaagaact caatattcct gtaaaattga ttggttttgg tgaaaaaatc
    59161 gatgatattg gagagtttaa ctcagaaaac tttatgaaag gtctcttgga aggcttaatc
    59221 taatcagaag caaaaatcct gcaaggtaca aacttgcagg atttttttat tcgaaacgac
    59281 catcttgacg ataggcgata tctggttgcc aagtccattt ggcaccgaat ttttcaagta
    59341 ggtcaaagct ggcttgaggt cccatgcttc cagctttata gtcatgaagt ggggcaccat
    59401 tttcagccca gagcttttca atacggtcaa tcaacttcca tgacgcacaa acttcatccc
    59461 agtggctaaa gttagttgag ttgttattta ggacatcata aatcaatttt tcgtatggtt
    59521 ctggagaagc accagttgca gtcgcatctg tacggtaatc aagtgagtta ggagccaagt
    59581 taaattcttc tcctacttgc ttcccattta ggctaagaga gaagccttct gttggttgaa
    59641 tatagatggt caaaatattt ggagcaagtg gttctccaaa gatagaatcc atttgtttaa
    59701 agacgatgtt gacatgagtt cctttttcag tcagtcgttt acctgtacgg aaaaagaaag
    59761 gaacaccacg gaatcgatcg ctgtctacaa agaaggcacc agatgtaaag gtttcagttg
    59821 ttgattctgg attcacattt ggctcgctac gataagagat gtatttcatg ccatcaatct
    59881 taccagagcg gtattgccca cggataaagt gttctttgag ttcttcatca gttggatgat
    59941 agaggttttt aaagacctta atcttttcag cacgaatctc gtcttttgtg aagcttgctg
    60001 gtttgtccat ggcgaggagc gaaagaagtt gtagagtgtg gttttggacc atgtcacgga
    60061 gggcaccgga ttggtcatag tagccaccac gttcttctac acccaagcgc tccgcaaagg
    60121 taatttgaac attgtcgata aaatccttgt tccaaacgtt ttcaaaaatc aagtttgcaa
    60181 agcgaactgc aaagatgctt tggatcattt ccttaccaag ataatggtcg atacggaaaa
    60241 tttgttcttc gtcaaatgtt gctaggagtt cgacattcaa cttgcttgca gttgcgtaat
    60301 ctgtaccaaa tggtttttca acgatcaagc gctcaaaacc tttgccatcg acaatgtttt
    60361 cagatttgag gtgtttggca atggttccaa agaactgagg tgccatagac aagaagaaga
    60421 gcttattgtg ttcagcttgg tatttttcat taagctcagc ttgtaattga cgcaaagcaa
    60481 tataatgttc cgaatcattg acatcatggc tttgatagta gaagtggcta gcaaattctt
    60541 gggcttgctc ggtactatct gccaaatcaa ggatggactc gacaactaca gattcaaaat
    60601 attccttact ccaaggtcta cgggcagttc caataacggc aaagtgcttg gaaagattgc
    60661 cggattgata tagtctaaaa agggaagggt agagcttgcg tttagccagg tctccactcg
    60721 caccgaaaat tgtaacaata accttagatg acatctagct acctaatttc tatttttatt
    60781 cctagtcttg ctaggtatga ggaaacctca tttcataaac ttaattctaa cataattttc
    60841 cgaaaaatca aaaattccaa tacgaggtag aaaaactgca aggaaatcct tacagtttga
    60901 gtttagacgt ttaagacctt atctaagaac tctttcagac gagggtgttg tgggttatca
    60961 aagatttggt caggtgttcc gtcttcaagg aactcgccat ctgcagtaaa gataacgcgg
    61021 ttggcaacct gacgagcaaa tcccatctca tgggttacga taatcatggt catgccttgc
    61081 tcagccaatt ccttcataac gttaagtacg tctccaacca tctcagggtc aagggcagaa
    61141 gttggttcat cgaagagcat gatgtctgga ttcattgcta ggccacgagc gatggccaca
    61201 cgttgttttt gaccacctga taggctatct ggattggcat tagctttatc tgctagtcca
    61261 accttttcaa gcaactccat tcccaattcc tcagcttctt ccttagtcat caacttgtgc
    61321 tcaataggag caaaggtgat gttgtccaat acagacatat gagggaagag gttgaagtgt
    61381 tggaatacca tgccgatatt ttcacggacg tggtcaacat tggttgtttt ttcagttaaa
    61441 tcatagccgt tcacagtgat gtgaccgcta gtgacttctt ctaaaagatt gaggctacgg
    61501 aggaaagttg acttaccaga acctgaagga ccgatgatac aaacaacatc tccttcatag
    61561 aacttagtcg taattccttt taggacttca ttttttccat agtacttgtg taaatcattt
    61621 acatcaattt ttaattttgc cattaacgaa tcctcttttc taagcgtttc gctagtctag
    61681 tcaaaagtgt gataattaca agatagaaga tagcaaggat tgcatacatc ttgaaacttt
    61741 ggtagttacg agcaatgata atcttaccag tttggaagag ttcaaccaaa ccgatagcag
    61801 atacgatagt tgtatcttta agagcgataa cgaattggtt gacaaagttt ggcaacatca
    61861 atttagttgc ttgtggcaag ataatcttac gcatggtttt tccataagag atacccaagc
    61921 ttcggctggc ttccatttgg ccaactggaa cggcctgaat accaccacga acgatttcag
    61981 cgatataagc agccgcattg agtgagaggg caattgttcc agctacaaag tcgttaattg
    62041 ggctttgttg gcctgtgata gactcgatga agtttggaat tccccagaag atgaaggctg
    62101 caagaatcat caatggaata ccacgaataa cgtcaacgaa aatctcagag atgacgcgaa
    62161 gagatttgta tgggctaacg ctaaacatac cgaagataat tccgatgaca atggcaatag
    62221 caaatgagat aagagctaga gcaagagtga taccaagacc gctaaggagt tgtttgtagt
    62281 tgttttgaag caagccccag agcgttgttt cgtcaacagt acttgttgaa gcagttgaag
    62341 attcgctagc taggtatttg tcaagaatct tttggaattc accgtttgct ttaaggtttg
    62401 caagtccgtt gttgaacatt tcaatcagtt ctggatttgc tcctttttta acggcaaagg
    62461 ctgtttcacc gattggagtt ccagagattg gagttttcaa tttttgacct tggctgatag
    62521 aatatttgag aacaggttca tcatccataa cggcatcaat ggcaccagtg tttaaactgt
    62581 catacattga agaaccatca gcaaaggttt tgattttgta accgtatttg ctttgatttt
    62641 ctgttaggaa ggtttgagaa gcagttccgt ttttaacacc gactgtcttt ccttttagat
    62701 cttcataaga agcaatattg cttgattctt tgacaccaag aatggtatta gcagtgtagt
    62761 atgattctga gaagtcaaaa gttgccttac gagcatctgt gacagacata ccagcaatga
    62821 taccatcggc ttgaccagct tggacagcac tgatagcagc atcaaaacca gggttggtga
    62881 tttcaatttc aaaaccttgg tctttagcga ttgccttaat caattccata tcaataccag
    62941 tgtattggtt gcttgaattt tggaaaacaa aaggtgcaaa agaagaatcg ctggcaatga
    63001 tatatttagc cttaacagga atagctttta atcctgcgag agtagttgta gttggcactg
    63061 ctgaagatga tgaagcagtc catttcttga taattttatc aagactacca tcttttttca
    63121 tttcagacaa ggcttggtta aattcagtaa ccaggtgctc gtatttactt ccttttttca
    63181 caccgaaagc aaaacttcct acagcttcac catccatttc aatatggagg tcttgacctt
    63241 ggttaatggc atattcgata acaggtttgt catccatcat ggcatcgatg gcaccagcac
    63301 tcaagctgtt gttcattaaa tcaccagtgt caaatgtttt aatagtaaag ccgtatttat
    63361 ctttgattgt ttcaaggaaa cgttgagcgg cagttccgtt tttaacacca acggttttgc
    63421 cagttaattg gtcgtacttg ctaattttgt gtgactttgt agtagcaatg acaacttttg
    63481 tatcatagta agtatcagac atggtgaaga ctttttcacg ttctttagtc tttgtcatcc
    63541 ctgccatgat agcgtcggct tgcccagctt gaaccgcatt gactgctgcg tcaaatccag
    63601 gataggacat ctgaatgttc cagcctttaa tctcagcgac tttgttaata atgtcaacat
    63661 caattccttt ataagtttga tctgaatctt taaactcaaa aggtgcatag gcggtatcag
    63721 aaacaatctt aatcgtttct gctttggcaa tacctaatga gaaaattggg aataaaatta
    63781 gcaaaaatgc tagaaatttt ttcttcattt ttagtctcct tttccgaata ttctctcatt
    63841 atatcagaaa aagtaaaaaa aggcaaattt ttatattttt cgtgtcagaa aatataacat
    63901 tgatttttcc ttttctttct tgaattgcta ttaaaaagtg ctataataat agtatatata
    63961 gaagaaaaga ggacggggat atgaagaaca aaagaatatt taaagacttc caagcttcaa
    64021 aaatgagttt aaacatttac acaagcccct tgttagcctt tgtttttgtc ttcataggag
    64081 agtttgtggc ttttactttg tatggtattg gcttgttagc tctcatcgga cttgctagaa
    64141 attttggaga ggctggtcaa aatcttgcaa cctacttgca gaccttgcat cagagcttga
    64201 cggataaaac aagtgacttt cgtttaattt taggattact ggcctttggt tttattctta
    64261 acactgtgtt cagatggaca agaaaagttg agaaaagacc tattcgaacc ttgggatttt
    64321 atagagagaa tttcctcagc aatcttctga aaggatttag tctaggcttg gcactttttc
    64381 ttctgacctt gttaggttta gtggtcttag gtcaatatcg tttggaatcc attcacttga
    64441 atccttattc tcttgccttt gtcgtcttta ctatcccatt ttggatttta caggggacag
    64501 cagaagaagt ggtggcccgt gcttggctac ttcctcaatt ggcctcaaga accaatctaa
    64561 aactagctat tcttatatct agcctgttct ttaccctgct tcatatgggc aattctggcc
    64621 tcacccctct atctctagta aatctctttt tattcggagt tgccatggct ctttatcttc
    64681 tcaaaactga tacagtttgg ggtgttgcag gtattcatgg tgcttggaat tttgctcagg
    64741 gtaatctctt tgggatttta gttagtggtc aaccgtcagg aacgtctctg atgacctttt
    64801 taccacaagg caatcaagat tggctatcag gtggttcttt tggcatagaa ggttccatta
    64861 tgacaagtct ggtattacta ctgctgattg tctatcttgc taataaatta aagaaagaaa
    64921 atgaaaggat gtgacttcgg tccgtccttt tcttcgtgaa aatactataa gtatgctaaa
    64981 ataggaatag cacatggaga gaggattctt atgatcaatc acattacaga taatcaattt
    65041 aaactagtat caaaatatca accatcagga gatcaacccc aagctatcga gcagttggtg
    65101 gataacattg aggggggaga aaaagctcag attctgatgg gggcgactgg aacagggaag
    65161 acctatacta tgagtcaggt catttctaaa gtcaataaac caactctggt tattgcccac
    65221 aataaaactc tggctggtca gctctatggg gagtttaagg aatttttccc tgaaaatgca
    65281 gttgagtatt tcgtatccta ctatgattat taccagccag aggcctatgt cccttctagc
    65341 gatacctata ttgagaagga tagttctgtc aatgacgaga ttgacaagct tcgccactca
    65401 gctacctcag cccttttgga gcgtaatgat gttattgtcg tggcctcagt ctcttgtatc
    65461 tatggtttgg gttcgcccaa ggaatacgct gatagtgtcg ttagtctccg tcctggtcta
    65521 gagatttctc gtgataaact cttgaatgac ttggtcgata ttcagtttga acgtaatgat
    65581 attgatttcc aacgcggaag atttcgcgtt cgtggggatg tggtagagat tttcccagct
    65641 tcccgagatg aacatgcctt tcgagtagaa ttttttggag acgaaattga ccgtatccgt
    65701 gaggttgagg ctctgacagg tcaggtattg ggagaggtgg atcatttggc gattttccca
    65761 gctactcact ttgtgaccaa tgacgaccat atggaagttg ccgttgccaa gattcaagca
    65821 gaattagaag agcagttagc tgtctttgaa aaggaaggta aactgcttga agcccagcgt
    65881 ttgaaacagc ggacagagta tgatatcgaa atgttgcgtg agatgggcta taccaatggg
    65941 gttgaaaatt attctcgcca catggatgga cggagcgaag gagagcctcc ttatacgctt
    66001 ctcgacttct tcccagatga tttcttgatt atgattgacg agagtcatat gaccataggg
    66061 caaatcaagg gcatgtacaa tggagaccgt tcgcgtaagg aaatgctagt aaattatggt
    66121 ttccgtttac cgtctgcctt ggacaatcgt cctctccgtc gtgaggagtt tgaaagccat
    66181 gtgcatcaga ttgtttacgt atcagcgaca cctggtgact atgaaaatga acagactgag
    66241 acggtgattg agcaaatcat tcgaccgaca gggcttttgg atcctgaggt ggaagtccgt
    66301 ccgactatgg gacagattga tgatctctta ggtgaaatca atgcccgtgt tgaaaagaat
    66361 gaacgaacct ttatcaccac cttgaccaag aaaatggcag aggacttgac cgactatttc
    66421 aaggaaatgg gcatcaaggt caagtacatg cactcggata tcaagacctt ggaacggacg
    66481 gagattatcc gtgatctccg cttgggtgtc tttgatgtct tggttggaat caatctcctt
    66541 cgtgaaggga ttgacgttcc tgaggttagc ttggttgcca ttctcgatgc tgacaaggaa
    66601 ggtttccttc gtaacgagcg tggactcatc cagaccattg ggcgtgccgc ccgtaacagt
    66661 gaaggtcatg tcatcatgta tgcagatacg gttacccagt ctatgcaacg tgctatcgat
    66721 gaaactgccc gccgtcggaa aattcagatg gcctataatg aagagcatgg tatcgtacca
    66781 cagacaatca agaaagaaat ccgtgacctg attgccgtga ccaaggcagt tgctaaggaa
    66841 gaggacaagg aagtcgacat caatagcctc aacaaacaag agcgcaaaga actcgtcaag
    66901 aaactagaaa aacaaatgca agaagccgtc gaagtgcttg actttgaact ggcggctcag
    66961 atccgtgata tgatgttgga agtcaaggcc ttggattagg ggaatagtat gatttattta
    67021 agaaagttaa agaaagaaga tttgatgtct ttatgggaaa tggcttattc acagcttaat
    67081 ccagtttgga aacagtatga tgctccctat tatgatgatt atcagtattt ttcaaatttt
    67141 aaagaattcg aactacaaaa atcagaatcc attttaagca actcaaatcg ccttggtatt
    67201 tttgttgatg ataaactagt tgggactgtt tcgcgttatt gggtatgtaa agaaacaaga
    67261 tggatggaat tgggaattgg tatttatgat aaaaaattct ggaacactgg tattgggaaa
    67321 gttgctatgt tgcagtggat agataggacg tttcaggatt acttggagtt ggagcatctg
    67381 ggtttgacaa cttggtcagg gaatcttggt atgatgaaac ttgctgaaaa attaagaatg
    67441 aaaaaagaag ctcatattcc aaaagttcgt tattatcaag gtaaatattt tgatagtatt
    67501 aaatatggta ttttgagaga agactgggag aaaataaatg acggttatta tcaaatcaat
    67561 ggaaactcct gaagagatag aaggtaaatc cctcgttcac tggcaaacgt ggagagaggc
    67621 ttatgatgac cttttgcctg cagaatttca ggagacaatg acattagaaa gatgtcgatt
    67681 ctttagtcaa aagtatccag aaaatacatt gattgcgata ggtgatctga aggtagttgg
    67741 ttttatcagt tatggtaact ttcgtgatga tactattcaa gctggtggaa ttattgcttt
    67801 atatgtttta aaagactatt acggaaaagg catagcacaa aagttaatga aagcagcttt
    67861 gactgctctt aatcattttt ctgaaatttt cttatgggta ttgaaagata acaagcgcgc
    67921 cattgctttc tatcaaaaaa tgggttttac ttttgatgga caagaaaaaa tacttgaact
    67981 tggaaagcct ataaaggaaa aacgaatggt gttctattct aaataatttt aaaaaagtaa
    68041 aagataatat ctctggtagt aagtctgaaa atttaataaa ttagaaagcg agtaaattta
    68101 tgtcccgttc ccaattaaca attttaacaa atatctgtct gattgaagac ctcgaaacgc
    68161 agcgcgtggt gatgcagtat cgcgcccctg aaaacaatcg ctggtctggt tatgcctttc
    68221 ctggaggtca tgtagaaaat gatgaggctt ttgcggagtc tgtcattcgt gaaatctacg
    68281 aagaaacagg gttgactatc caaaatcctc aacttgtcgg cattaaaaat tggccactag
    68341 atacaggtgg gcgctatatt gtcatttgtt ataaggcgac tgagttctct ggtacccttc
    68401 aatcttcaga agagggagaa gtttcttggg tgcaaaaaga ccagattcca aacttaaatc
    68461 tggcctatga tatgctacca ttgatggaaa tgatggaagc tcccgacaag tcagagtttt
    68521 tctaccctcg ccgtacagaa gacgattggg aaaagaaaat cttctagtct tttactaaat
    68581 aacctagctg atccaaggcc tcctcgatat agtggaggtc ttgttgtgtt tcggcttcga
    68641 ctaggtggta atggatgcca tctgtcaatt cagatagagg tctaaagtca gaatgctcga
    68701 cttgttctag aaaatgttgc acatctctgc gacaagacag tttaagcaag gtttcaattt
    68761 ctccataaac gggatggtca atcaaggtat tctggacatg cccaccatta tcgacaatag
    68821 caaggagttc ctgaccgatt tcttcaactt catgtttcac tttgaaaagt ttgtgaacat
    68881 aaggattggt atcaatttgc ttatagatgt agccacgatt ggtggatagg ataggagcgc
    68941 catcggctct caaaattgca atgtcctgca caatgacctg acgtgtgaca tgaaaatgtt
    69001 ccgccaaact ttggccatta agggctttag gagcttcttt caagagttgg agcagggctt
    69061 gtttgcgatc ttttgtcata gcttttcctt ttaacggcgt tttcgaagca ctttatagac
    69121 agctagtgct aatgtatagt ctaccatact atggataatt gtgccaaatc caactagtac
    69181 aaatagaaca tagaacatgt tttctacatt ggtacccgaa gttgcgtaaa aaaggacaca
    69241 ggctaatact tcagcaaggg catgaacaac agccaaaaca aaattgaaaa cccaggaaga
    69301 ttttggttta tctagggtat cggggaattt ttgtaggtaa agagctccta aagcaccaaa
    69361 agatatatgg gaaaaagccc gaaaaacgat aaccatggga tagccagcca tcaaaaatcc
    69421 aaaactagag gctaggatga caaaaactgc catcaagggc gacaagaaca tggctataaa
    69481 aatagcgatg tggctcccca aagtatagga agcaggtgga atgacaatct tgaaaggcat
    69541 aacaattgga atcaaaatcg caatagccgt taaaagggct gtcattgtca taaattgtgt
    69601 ctttttccgt gtattcacaa gaatctcctt tttaactgca tatacactag tatggtacaa
    69661 taaaccagac aataaagcaa gaatttactt gggtttatag atcatttttt agttaaaagt
    69721 tatagtagat tgaaact
//
LOCUS       DAVBOU010000002        68088 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBOU010000002 DAVBOU010000000
VERSION     DAVBOU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.002"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ879_000071"
     CDS             <1..116
                     /locus_tag="VQ879_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3142309.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ879_000072"
     CDS             135..1652
                     /locus_tag="VQ879_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3142310.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ879_000073"
     CDS             1777..3105
                     /locus_tag="VQ879_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3142311.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ879_000074"
     CDS             3358..4224
                     /locus_tag="VQ879_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3142312.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ879_000075"
     CDS             4240..5079
                     /locus_tag="VQ879_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3142313.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ879_000076"
     CDS             5351..5803
                     /locus_tag="VQ879_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3142314.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ879_000077"
     CDS             5900..6244
                     /locus_tag="VQ879_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142315.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ879_000078"
     CDS             6528..7172
                     /locus_tag="VQ879_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3142316.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ879_000079"
     CDS             7341..8258
                     /locus_tag="VQ879_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3142317.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ879_000080"
     CDS             8276..9160
                     /locus_tag="VQ879_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3142318.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ879_000081"
     CDS             complement(9176..10027)
                     /locus_tag="VQ879_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3142319.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ879_000082"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ879_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3142320.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ879_000083"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ879_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3142321.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ879_000084"
     CDS             13086..14129
                     /locus_tag="VQ879_000084"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3142322.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ879_000085"
     CDS             14213..15586
                     /locus_tag="VQ879_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3142323.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ879_000086"
     CDS             15573..16184
                     /locus_tag="VQ879_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3142324.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ879_000087"
     CDS             16275..16979
                     /locus_tag="VQ879_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3142325.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ879_000088"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ879_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3142326.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ879_000089"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ879_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3142327.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ879_000090"
     CDS             19852..20523
                     /locus_tag="VQ879_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3142328.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ879_000091"
     CDS             20533..21072
                     /locus_tag="VQ879_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3142329.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ879_000092"
     CDS             21072..21335
                     /locus_tag="VQ879_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3142330.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ879_000093"
     CDS             21332..22117
                     /locus_tag="VQ879_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3142331.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ879_000094"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ879_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3142332.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ879_000095"
     CDS             23262..26054
                     /locus_tag="VQ879_000095"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3142333.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ879_000096"
     CDS             26457..26837
                     /locus_tag="VQ879_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142334.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ879_000097"
     CDS             27031..27321
                     /locus_tag="VQ879_000097"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142335.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ879_000098"
     CDS             27372..28064
                     /locus_tag="VQ879_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3142336.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ879_000099"
     CDS             28117..30528
                     /locus_tag="VQ879_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3142337.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ879_000100"
     CDS             30778..31479
                     /locus_tag="VQ879_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142338.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ879_000101"
     CDS             31481..34189
                     /locus_tag="VQ879_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3142339.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ879_000102"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ879_000102"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3142340.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ879_000103"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ879_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3142341.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ879_000104"
     CDS             complement(35860..36708)
                     /locus_tag="VQ879_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3142342.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ879_000105"
     CDS             complement(36705..37427)
                     /locus_tag="VQ879_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3142343.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ879_000106"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ879_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3142344.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ879_000107"
     CDS             complement(39733..40362)
                     /locus_tag="VQ879_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3142345.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ879_000108"
     CDS             41358..43580
                     /locus_tag="VQ879_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3142346.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ879_000109"
     CDS             43610..44053
                     /locus_tag="VQ879_000109"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3142347.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ879_000110"
     CDS             complement(44320..44505)
                     /locus_tag="VQ879_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142348.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ879_000111"
     CDS             complement(44524..44937)
                     /locus_tag="VQ879_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142349.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ879_000112"
     CDS             complement(45068..45715)
                     /locus_tag="VQ879_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3142350.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ879_000113"
     CDS             complement(45741..45932)
                     /locus_tag="VQ879_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142351.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ879_000114"
     CDS             complement(45913..46563)
                     /locus_tag="VQ879_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3142352.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ879_000115"
     CDS             46675..47517
                     /locus_tag="VQ879_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3142353.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ879_000116"
     CDS             47593..48030
                     /locus_tag="VQ879_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3142354.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ879_000117"
     CDS             48098..48400
                     /locus_tag="VQ879_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142355.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ879_000118"
     CDS             complement(48491..49564)
                     /locus_tag="VQ879_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3142356.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ879_000119"
     CDS             49720..50397
                     /locus_tag="VQ879_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3142357.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ879_000120"
     CDS             50390..51364
                     /locus_tag="VQ879_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3142358.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ879_000121"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ879_000121"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3142359.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ879_000122"
     CDS             complement(53414..53737)
                     /locus_tag="VQ879_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3142360.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ879_000123"
     CDS             54596..55225
                     /locus_tag="VQ879_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3142361.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ879_000124"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ879_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3142362.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ879_000125"
     CDS             56451..57065
                     /locus_tag="VQ879_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3142363.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ879_000126"
     CDS             complement(57358..58107)
                     /locus_tag="VQ879_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3142364.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ879_000127"
     CDS             58240..60576
                     /locus_tag="VQ879_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3142365.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ879_000128"
     CDS             61105..62568
                     /locus_tag="VQ879_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3142366.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ879_000129"
     CDS             62561..62989
                     /locus_tag="VQ879_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3142367.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ879_000130"
     CDS             62967..63416
                     /locus_tag="VQ879_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3142368.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ879_000131"
     CDS             63444..63755
                     /locus_tag="VQ879_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3142369.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ879_000132"
     CDS             63781..64866
                     /locus_tag="VQ879_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3142370.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ879_000133"
     CDS             64877..65572
                     /locus_tag="VQ879_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3142371.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ879_000134"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ879_000134"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3142372.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68088
                     /locus_tag="VQ879_000135"
     CDS             67952..>68088
                     /locus_tag="VQ879_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3142373.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YG"
BASE COUNT        20141 a        12447 c        15285 g        20215 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa tccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg tgggcttaga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga taaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgttggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggtcttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccagt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt cgccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagga ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatgg
//
LOCUS       DAVBOU010000003        67910 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBOU010000003 DAVBOU010000000
VERSION     DAVBOU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67910
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.003"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            451..636
                     /locus_tag="VQ879_000136"
                     /pseudo
     CDS             451..636
                     /locus_tag="VQ879_000136"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1248..1532
                     /locus_tag="VQ879_000137"
     CDS             1248..1532
                     /locus_tag="VQ879_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142374.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1525..1763
                     /locus_tag="VQ879_000138"
                     /pseudo
     CDS             1525..1763
                     /locus_tag="VQ879_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1859..2077
                     /locus_tag="VQ879_000139"
     CDS             1859..2077
                     /locus_tag="VQ879_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142375.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ879_000140"
     CDS             complement(2449..4773)
                     /gene="pflB"
                     /locus_tag="VQ879_000140"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3142376.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5168..6229
                     /gene="dinB"
                     /locus_tag="VQ879_000141"
     CDS             5168..6229
                     /gene="dinB"
                     /locus_tag="VQ879_000141"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3142377.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(6376..7221)
                     /locus_tag="VQ879_000142"
     CDS             complement(6376..7221)
                     /locus_tag="VQ879_000142"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3142378.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7477..8345
                     /locus_tag="VQ879_000143"
                     /pseudo
     CDS             7477..8345
                     /locus_tag="VQ879_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8646..10535)
                     /locus_tag="VQ879_000144"
     CDS             complement(8646..10535)
                     /locus_tag="VQ879_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3142379.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            10673..12238
                     /locus_tag="VQ879_000145"
     CDS             10673..12238
                     /locus_tag="VQ879_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3142380.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12238..12978
                     /locus_tag="VQ879_000146"
     CDS             12238..12978
                     /locus_tag="VQ879_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3142381.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(13087..13302)
                     /locus_tag="VQ879_000147"
     CDS             complement(13087..13302)
                     /locus_tag="VQ879_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142382.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ879_000148"
     CDS             complement(14173..15423)
                     /gene="ilvA"
                     /locus_tag="VQ879_000148"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3142383.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(15473..15829)
                     /locus_tag="VQ879_000149"
     CDS             complement(15473..15829)
                     /locus_tag="VQ879_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3142384.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(16067..16303)
                     /locus_tag="VQ879_000150"
     CDS             complement(16067..16303)
                     /locus_tag="VQ879_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142385.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ879_000151"
     CDS             complement(16410..17432)
                     /gene="ilvC"
                     /locus_tag="VQ879_000151"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3142386.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ879_000152"
     CDS             complement(17498..17974)
                     /gene="ilvN"
                     /locus_tag="VQ879_000152"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3142387.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(17967..19667)
                     /locus_tag="VQ879_000153"
     CDS             complement(17967..19667)
                     /locus_tag="VQ879_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3142388.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(19868..21535)
                     /locus_tag="VQ879_000154"
     CDS             complement(19868..21535)
                     /locus_tag="VQ879_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3142389.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21538..21903)
                     /locus_tag="VQ879_000155"
     CDS             complement(21538..21903)
                     /locus_tag="VQ879_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3142390.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(22060..22248)
                     /locus_tag="VQ879_000156"
     CDS             complement(22060..22248)
                     /locus_tag="VQ879_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3142391.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(22364..22849)
                     /locus_tag="VQ879_000157"
     CDS             complement(22364..22849)
                     /locus_tag="VQ879_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET3142392.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(23118..24662)
                     /locus_tag="VQ879_000158"
     CDS             complement(23118..24662)
                     /locus_tag="VQ879_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3142393.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            24875..25177
                     /gene="gatC"
                     /locus_tag="VQ879_000159"
     CDS             24875..25177
                     /gene="gatC"
                     /locus_tag="VQ879_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3142394.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            25177..26643
                     /gene="gatA"
                     /locus_tag="VQ879_000160"
     CDS             25177..26643
                     /gene="gatA"
                     /locus_tag="VQ879_000160"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3142395.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            26643..28085
                     /gene="gatB"
                     /locus_tag="VQ879_000161"
     CDS             26643..28085
                     /gene="gatB"
                     /locus_tag="VQ879_000161"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3142396.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            28209..29252
                     /locus_tag="VQ879_000162"
     CDS             28209..29252
                     /locus_tag="VQ879_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3142397.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            29630..30190
                     /gene="efp"
                     /locus_tag="VQ879_000163"
     CDS             29630..30190
                     /gene="efp"
                     /locus_tag="VQ879_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3142398.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            30212..30601
                     /locus_tag="VQ879_000164"
     CDS             30212..30601
                     /locus_tag="VQ879_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3142399.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            30594..31016
                     /gene="nusB"
                     /locus_tag="VQ879_000165"
     CDS             30594..31016
                     /gene="nusB"
                     /locus_tag="VQ879_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3142400.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(31066..31302)
                     /locus_tag="VQ879_000166"
     CDS             complement(31066..31302)
                     /locus_tag="VQ879_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3142401.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(31315..31788)
                     /locus_tag="VQ879_000167"
     CDS             complement(31315..31788)
                     /locus_tag="VQ879_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142402.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ879_000168"
     CDS             complement(31806..31991)
                     /gene="briC"
                     /locus_tag="VQ879_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3142403.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(32150..32917)
                     /locus_tag="VQ879_000169"
     CDS             complement(32150..32917)
                     /locus_tag="VQ879_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3142404.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(32914..33780)
                     /locus_tag="VQ879_000170"
     CDS             complement(32914..33780)
                     /locus_tag="VQ879_000170"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3142405.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ879_000171"
     CDS             complement(33817..35184)
                     /gene="accC"
                     /locus_tag="VQ879_000171"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3142406.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ879_000172"
     CDS             complement(35196..35618)
                     /gene="fabZ"
                     /locus_tag="VQ879_000172"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3142407.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(35615..36100)
                     /locus_tag="VQ879_000173"
     CDS             complement(35615..36100)
                     /locus_tag="VQ879_000173"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3142408.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ879_000174"
     CDS             complement(36103..37338)
                     /gene="fabF"
                     /locus_tag="VQ879_000174"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3142409.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ879_000175"
     CDS             complement(37360..38091)
                     /gene="fabG"
                     /locus_tag="VQ879_000175"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3142410.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ879_000176"
     CDS             complement(38125..39045)
                     /gene="fabD"
                     /locus_tag="VQ879_000176"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3142411.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ879_000177"
     CDS             complement(39038..40012)
                     /gene="fabK"
                     /locus_tag="VQ879_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3142412.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(40131..40355)
                     /locus_tag="VQ879_000178"
     CDS             complement(40131..40355)
                     /locus_tag="VQ879_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3142413.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(40415..41389)
                     /locus_tag="VQ879_000179"
     CDS             complement(40415..41389)
                     /locus_tag="VQ879_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3142414.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(41389..41823)
                     /locus_tag="VQ879_000180"
     CDS             complement(41389..41823)
                     /locus_tag="VQ879_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3142415.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(41917..42702)
                     /locus_tag="VQ879_000181"
     CDS             complement(41917..42702)
                     /locus_tag="VQ879_000181"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3142416.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            43027..44391
                     /locus_tag="VQ879_000182"
     CDS             43027..44391
                     /locus_tag="VQ879_000182"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3142417.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            44394..44765
                     /locus_tag="VQ879_000183"
     CDS             44394..44765
                     /locus_tag="VQ879_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3142418.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            44979..46253
                     /gene="serS"
                     /locus_tag="VQ879_000184"
     CDS             44979..46253
                     /gene="serS"
                     /locus_tag="VQ879_000184"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3142419.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(46278..47177)
                     /locus_tag="VQ879_000185"
     CDS             complement(46278..47177)
                     /locus_tag="VQ879_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3142420.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(47287..47835)
                     /locus_tag="VQ879_000186"
     CDS             complement(47287..47835)
                     /locus_tag="VQ879_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3142421.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(48053..49375)
                     /locus_tag="VQ879_000187"
     CDS             complement(48053..49375)
                     /locus_tag="VQ879_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3142422.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(49466..49554)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(49718..52054)
                     /locus_tag="VQ879_000188"
     CDS             complement(49718..52054)
                     /locus_tag="VQ879_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3142423.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(52158..52706)
                     /locus_tag="VQ879_000189"
     CDS             complement(52158..52706)
                     /locus_tag="VQ879_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3142424.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ879_000190"
     CDS             complement(52703..53005)
                     /gene="zapA"
                     /locus_tag="VQ879_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3142425.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            53092..53964
                     /locus_tag="VQ879_000191"
     CDS             53092..53964
                     /locus_tag="VQ879_000191"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3142426.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            53976..54590
                     /gene="lepB"
                     /locus_tag="VQ879_000192"
     CDS             53976..54590
                     /gene="lepB"
                     /locus_tag="VQ879_000192"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3142427.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            54718..57084
                     /locus_tag="VQ879_000193"
     CDS             54718..57084
                     /locus_tag="VQ879_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3142428.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(57132..58415)
                     /locus_tag="VQ879_000194"
     CDS             complement(57132..58415)
                     /locus_tag="VQ879_000194"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3142429.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(58576..58968)
                     /locus_tag="VQ879_000195"
     CDS             complement(58576..58968)
                     /locus_tag="VQ879_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3142430.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(59267..59896)
                     /locus_tag="VQ879_000196"
     CDS             complement(59267..59896)
                     /locus_tag="VQ879_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3142431.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(59941..60180)
                     /locus_tag="VQ879_000197"
     CDS             complement(59941..60180)
                     /locus_tag="VQ879_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142432.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(60330..60596)
                     /locus_tag="VQ879_000198"
                     /pseudo
     CDS             complement(60330..60596)
                     /locus_tag="VQ879_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(60621..60932)
                     /locus_tag="VQ879_000199"
     CDS             complement(60621..60932)
                     /locus_tag="VQ879_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3142433.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(60857..61099)
                     /locus_tag="VQ879_000200"
     CDS             complement(60857..61099)
                     /locus_tag="VQ879_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3142434.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(61100..61732)
                     /locus_tag="VQ879_000201"
     CDS             complement(61100..61732)
                     /locus_tag="VQ879_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3142435.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(61746..62741)
                     /locus_tag="VQ879_000202"
     CDS             complement(61746..62741)
                     /locus_tag="VQ879_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3142436.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(62738..63436)
                     /locus_tag="VQ879_000203"
     CDS             complement(62738..63436)
                     /locus_tag="VQ879_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3142437.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(63513..64523)
                     /locus_tag="VQ879_000204"
     CDS             complement(63513..64523)
                     /locus_tag="VQ879_000204"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3142438.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(64507..65514)
                     /locus_tag="VQ879_000205"
     CDS             complement(64507..65514)
                     /locus_tag="VQ879_000205"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3142439.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ879_000206"
     CDS             complement(65501..66454)
                     /gene="mvaD"
                     /locus_tag="VQ879_000206"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3142440.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ879_000207"
     CDS             complement(66436..67314)
                     /gene="mvk"
                     /locus_tag="VQ879_000207"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3142441.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(67436..67558)
                     /locus_tag="VQ879_000208"
     CDS             complement(67436..67558)
                     /locus_tag="VQ879_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3142442.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        20218 a        15194 c        12695 g        19803 t
ORIGIN      
        1 gaactgacga agtcagtaac atctatacgg taaggcgacg ctgacgtggt ttgaagagat
       61 tttcgaaaag tattagttaa atcttgttta atatctctac accatactat tttacatata
      121 ttatttagcg ccacatagta ctgaactctc tccaaaaacg gttatgcctc tttgaatagg
      181 gcgttatcac aagaaaagca tctccacgtt tcaacttcat atggctcaaa aacaatcaat
      241 tgatgctaaa acctgtacct agatgtttcg gttcataaaa ccatgaaact gtaaaagtgg
      301 atgaaattga tagcgatagt caaatcaaga ggcatcataa ctctaaaaag tcacaatata
      361 taagttcatc ctcggaaaaa tatcattcta attgttgaaa tggatatata aacaggggta
      421 ttaacattaa atgctcatga aacaacgaat acaggtatca aaactatgac aaaacaagtc
      481 cctaaattta ctaaagacac tgctcaactt tacacctgta aatggttgtt gtataataaa
      541 gttacaaaga tgtacgacca cactgttgta aatcatagtg ttcgcgaata tattactgat
      601 agcatttcta caaatacaat tgaagaggct ggataggctt taaacgaaat atgtcagtgt
      661 tttggcattc ctagccttaa tatcatttaa agaattgtat agataaaatt ttttccaata
      721 cagacactcg taacaactgc ttcatttttc taccaacata tttaggaaca ggataagata
      781 caagaggatt aatccataaa tcagttctat accaatctaa gacaaataag ctaaaaaaac
      841 gattgataat aagcaaatag attccaaatt ttctctatct gctcatttta ataaacaata
      901 ctagtgtaac tatccttcca gtcagaaact tgtcaaatca caccgaaaac tcttctaaaa
      961 tttatctcgt taggcaatca agcaaaaact cgacgatagt acaaacatta tcatacagaa
     1021 ttgactgcct aaattatata ctttagtaag gttttcggat aagaaaaaag gttcatttta
     1081 catttctaaa cattcttttc taagatgaaa aacagaattt ttcgattgtg atttaaagca
     1141 acaagaagat tttcagtatc atcctataga tacgagctaa ttaagaaaaa ctacattttt
     1201 gaatataaac tacaataata taaactaaat tttataggag gaagacaatg gattggtacg
     1261 attatatgat acaggcatcc aaacaatcac aattcaacgc aagccattgg tttcgctatt
     1321 tgcgaaaagt tatttttgaa gactattctt atttaacaaa ccaagatgta gaaaagttgc
     1381 tagactccaa agaactaacc cgttttcaaa aaattagctt gaagtatgcc tttcaagagc
     1441 atactccaac tcataaatat gtgatttcat taaataaacc tgctaagtta accaatgttc
     1501 aaaaattgat ggagaaatac aaacatggat aaaatgaaac cggtcttcca agccctaaat
     1561 aagaaattaa ttcaggaaaa tctgacttta acaattatgg ttatgtctta gaatatcatg
     1621 gtttacgtgc cacacaagat gttgatgctt tttatgacca aaatcagaaa atcaatgaaa
     1681 ttattgctcg tgtaggaaaa cagtttaatc ttaacatcca cgaagagtta tggctcaaca
     1741 atcatgttgc aaagcaaata tgaacaaaca acctccctta agtttatgcg aatccttgta
     1801 ctcatttgag aatctgaccg ttttagtagt ccctattgag tatgtgttag gaatgaagat
     1861 gatgagtatc agagagcagg atttgcaaga tattggtgca attattaaat acaaaaactt
     1921 tcattcacca ttcgatacct ttaaatattt aaaagacatg ggatttgata ctattgacct
     1981 ctctgttcta ttagaaggtt ttagttatgc ttatggtatg gattggttag aaaaattttt
     2041 taaagaaaat caagataaac ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc
     2101 aattagccag tcgtcttatt tttatgatga aatgaaatga aataaaatcg gaacaaatca
     2161 cttagagaat tccagtcaat ttctagcact gtttgagccg tttcagcgga ctatagtaaa
     2221 atgaaataag aataggacaa atcgatcagg acagtcaaat cgatttctaa gaatgtttta
     2281 gaagtaaagg tgtactattc tagtttcaat ctattatatt tcagattcgg tccactgttc
     2341 cttcccaaaa acattgcata ttgcgccgaa ggaattgctc atactatccc aagcacaaaa
     2401 ccctcagtcg tttgaccgag ggttcctttt tattattcaa gaacttgatt agctcaatgc
     2461 atccaaggcg tcatccattg aaagaacttc gtggaagaca cgttgtgtca attcagtttt
     2521 ttgttctgga gtgaggtatt tagtgtttac acagtatcca gagatacgta cgataacgtc
     2581 ttcgcctgac atgatttttt cgtaaacatc gttcaagtcc ataacgttca agttaacgtg
     2641 ttgtccaccg ttttcgaagt aaccatcaag gattgttacc aagttatcaa cttgttcatc
     2701 acgagtctta ccaagagcgc gaggtgatac ttgtgtagtc aatgagatac cgtcagctgc
     2761 ataactaaag tcaaggctag aaagtgagtt caagttttgc aaccaaccac ctttagcttt
     2821 gttagatggg ttagcacctg gtgagaagaa ttcaagttta gacaagttca cagaaccatc
     2881 ttcgttgagg tatacacctt tgtgaactgg tgagttacca gtttgtttag agtaagcaac
     2941 gttagatgtg attgtcaaaa gtgatactgt agcttctgcg tctttgtata gtttgtggct
     3001 acgtagacga gttgtgtaag cttcgatcaa ccattctgcc aattcgtttg aacgtgggtc
     3061 atcttcaccc cagcgtgggt agtcaccgat tgtttcgtaa tcgtagatgt agccatcttc
     3121 gtcacggatt ggtttaactg tagcgtattt gatagctgac aatgtatcaa cagtgttagc
     3181 aaatccacag ataccgaatc ccatgttggc acgttgttta gttggcaaga aggccatttg
     3241 aacagcttcg tagttgtacc tatcagtcat gtagtggatg atgttcaagg catctacgta
     3301 agtgtcagtc aaccagtcaa gagatttttc aaagttcgct ttaactgatt cgaattcaag
     3361 aacttcgtca cgaataggat cgatgtcaaa tactttgtag tctttgtgaa catcgtcgta
     3421 accaccattc aaaccagtaa gaagggcttt aagaacgttt acacgagcac cgaagtactg
     3481 gatgttgtgg cgttgttctt cattttctgg atcaagtgga gacacacagc atgagataca
     3541 gctcatttca ccatatccgt ctttagccat tgttgttaca ccttcgtatt ggatagaaga
     3601 gtgtttgtgg ctcatgtgca tacagtagcg acggaagttg tatggcaatt tgtcagtcca
     3661 aagaactgtc aagtttggtt ctggtgagtt accgatgttg tcaagagtgt tcaagaaacg
     3721 gtagtccatc ttagtaacac ggtgacgacc gtcgttaccc ataccagcca tagaagttgt
     3781 gataaaggtt gggtcacctg agtacaattg gtcataagct tttgtacgag caaatttaac
     3841 tgtacgaagt ttcataacga aatcatcaac gaattcttgg atttctgatt cagtaaatgt
     3901 accacgagca aggtcacgtt ctgcaaagat gtccaatacg attggtacac gacctagaga
     3961 tgtagcagca ccgttaatca cacggcagac agccatgaaa gcaatgttaa cccattggat
     4021 tgcttctttc acgttcatcg ctggtttgcg aacatcaacc ccgtaaaggt cacccaggcg
     4081 aacaacttgt tgcaatgctt ggtattgaag gtttacttct tcacgaagac ggattgtttc
     4141 ttcatcgatt tctttgattg cattccagtc gtttactttt tcttgcatca agtagtctgc
     4201 accgtaaaga gcaagacgtg cgtaaacacc gatgatacgt ccgcgtgagt atgcatctgg
     4261 aagaccagtt acagtgtgtg catgacgagc gcgacgaata tttgaagtgt aggcacggaa
     4321 aataccgtcg ttaactgttg ttacatattt agtgaagatt tcgtgaacag ctgggtctgg
     4381 ttcgtatcca ttttctttta aagtagtttc agccatacgg ataccacctt ttggcatgaa
     4441 gttcaatttg aagagttcat cattttggat accaaagata acttcatttt ctttgtcgat
     4501 aaatccagca gggatatcag cgatagatgt tggacgagtg tccattggga aacgagtttc
     4561 ttcgtagtgt gctttagttt cttctacaat tttcttgatg tgaagtgaac gctctgttgg
     4621 tcctgcaagg aagctttcgt ctccatcata aggtgtgtag ttagcttgta caaagcgtga
     4681 tacacttgct ttttctttcc aatctacgcc tttgaagcct tcccaagctt tgtcaaaaat
     4741 atcttgtgct tcaacaaccg tcttaacaac catattaatg tcctcttttt tctagtaaca
     4801 gtcatctgtt acattcataa gacaagtata ccataaagta atcgatttca acaagtgcaa
     4861 aatccctatt tttacacttt cttttctaaa acagtctata ttttatttca aactgtatta
     4921 tatttttgaa aaaaataaag tccttttttc tttttttcag aaaaaagggt ataataaaag
     4981 aaaataagca gtaacactca atggaaatcg aaaagcaaac taggaagcta gccgcaggct
     5041 gctcaaagca ctgctttgag gttgtaaata gaactgacga agtcagctca aaatactgtt
     5101 ttgaggttgc agatggaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaaaggt
     5161 gctaggcatg ttgatttttc ctttgttaaa tgatttgtca agaaaaatca tccatattga
     5221 catggatgcc ttttttgctg cggtggaaat caaggataat cctaaactca gaggaaaacc
     5281 tgtcattatt ggaagcgacc ctcggcaaac aggtggacgg ggagtcgttt ctacctgtag
     5341 ctatgaggct cgagcttttg gtgtccattc tgccatgagt tccaaggaag cttatgaacg
     5401 ttgtccccag gccgtcttta tctcaggaaa ttatgagaaa tacaaagctg tgggactcca
     5461 gattcgagct atttttaagc gctatacaga tttgattgaa cccatgagca ttgacgaagc
     5521 ctatttggat gtgacagaaa ataaactcgg tatcaagtca gcggtcaaaa ttgctcgcct
     5581 cattcaaaaa gatatctggc aagaactcca tctaactgct tctgccggta tttcctacaa
     5641 caagttctta gctaaaatgg cgagtgatta tcaaaaacct catggtttga cagtgattct
     5701 acctgaacag gctgagaatt ttctcaaaca aatggatatt tccaaatttc atggagtagg
     5761 aaaaaagaca gtagaacgtc ttcatcaaat gggcgttttt actggtgctg atttacttga
     5821 agttcctgag gtgaccctaa tagaccgttt tggtagacta ggctatgatc tgtatcgaaa
     5881 ggctcgtggc attcacaact ctccagtcaa atccaatcgc atccgtaaat caatcggcaa
     5941 ggagaaaacc tacgggaaga ttctccgtgc tgaggaagat atcaaaaaag agctgactct
     6001 tctatcagaa aaagtcgctc tcaatctaca tcaacaagaa aaagctggaa aaattgtcat
     6061 tttgaaaatc cgctacgagg acttttcaac tcttaccaaa cgaaaaagtc ttgctcaaaa
     6121 aacacaagat gctagtcaga taagccaaat agccctgcaa ctctatgaag aattaagcga
     6181 gaaagaaaga ggtgtccgcc tattggggat taccctgact ggattttaaa gctcaatgaa
     6241 aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt ttgaggttgc
     6301 agataaagct gacgcggttt gaagagattt tctaagagta taaaaccttg aagagttgcc
     6361 ccttcaaggt ttttcttata caaataaacg gacaaaactg taaagtagca aaacactacc
     6421 aagcacgata cggtatttac caaaaagggt gaagtcgtgt tttttcacat agctggtcaa
     6481 gaagcgaata gccaccatgc tgaccgcaaa agctactccc atcgcgacca agagcaaaaa
     6541 caattgccca aagctcaaga gttctccggc tttcacaaat ttgaaaatct ttaaggcact
     6601 agctccaaac ataacgggaa tcccaagata gaaggtaaat tctgtcacaa ctgaacgact
     6661 ggttccattt aacaaaccac cgacaatcgt tgcacctgaa cggctagtcc ctggtaaaag
     6721 agcaagaact tggaagagtc cgatatagaa agcggtcgta taaggaagct tgtccaactc
     6781 tgttacactt ggctcgatag cacgcgcttt attgcgcttt tccaaataga tgaaggcaac
     6841 cccgtagata atcaacatga gagcaactga aaccatgtta tggaagtggg tatcaaacca
     6901 atcatcaaat ttaaagacac caagtaaagg caaagtggca atcaagacct tcaaccatag
     6961 tctccaagtc ttacgaactt cctgtttgtc cttagtcggt ttaaaaggat tgagcttgtt
     7021 aaaataaatc accataactg ctaaaatagc accaagctga atcacgacat taaacatgga
     7081 cataaaggct tcattttgat tttggtattg gataaactcc tctgctaaaa tcaagtgacc
     7141 tgtactggaa atcggcaacc attccgtaat tccttcaaca atcccgaaga agatagattt
     7201 taaaatttca ataagataca tatatttctc cttatattat atttaacgca gttagctact
     7261 gccaaagccc aagtggtata cttggaataa gccactgtgg attagttcat ttcctccaat
     7321 cgcttgacga tttccgaaag ggtctaacaa cagctttttg tttcaattgg taatgagttt
     7381 gataacgcat agacgtttta tctcgtctaa ggtaacaagg caaaaagttc gtggataacc
     7441 aagtagactt gaaatactat atctggaggt actcccatgc tttatgtggg cattgatgtc
     7501 gctaaaaata aacacgatgt tacagccttg aatgttcgag gaaaactgtt cttaaaccac
     7561 tcactttttc aaataataaa gctggttttg aactcttaga tctgtctttt cgacagctca
     7621 accaagactg tctcatcgct cttaaacttc tttctgaccc caatcgtgaa caatttcaac
     7681 acgataatcg gcaagtagaa ctaaaaatac tggctagaca tattcatcgt ctcaagaaaa
     7741 aacagtctga ttggaaagta caatacactc gttgtcttga tatcatcttt cctgagttgg
     7801 ataaaatcgt tggaaagcat tcagaatata cctaccaact cttgacacgc taccctaatc
     7861 ctcagaaaag gcttgaggca agatttgata agctgataga aattaagcga ttgaccgctt
     7921 ctaaaattca ggatatcctc tcagtcgcac ctcgttctat cggaacaaca tctcctgctc
     7981 gtgaattcga aatcatcgaa atcatcaaac attacaagag gctcattgac aaggcggaaa
     8041 catgtgtcaa tgacttgatg gctgagttca actcggtcat cacgacggtt actgggattg
     8101 ggggtcgttt aggggcggtc attttagccg agattcgaaa tattcatgcc tttgataatc
     8161 ctgctcaatt acaagctttc gctggactgg attcttctat ttatcagtca ggtcagattg
     8221 atttagctgg aagaatgatc aaacggggtt cccctcatct gcggtgggca ctcatacaag
     8281 ctgccaaagc atgcgctcgc ttttcacctg cttttaaggc ctatcttaag actaagttag
     8341 aataaggaaa acattacaat gtagccatca tccaccttgc aaaaaaactt atccgaaccc
     8401 tgttttatat cctaaaaaag agctgccatt tgacgaacaa aaagtgatgt aatttctgaa
     8461 attaacacag gattaccttt gaaaaaatgg actttttcaa gggctttttg ccgtgctcta
     8521 aaatcatcgc caaatcatca aattgaaata agaaatagtt tagataaaac tattgacttt
     8581 tcttatagtt tgtctttctt ctatcttcca ttatatcata ctttttcagt ctatggtagc
     8641 tctctttaaa aggctccgat actgccgcca cctccgcctc cagagaagcc accgccagaa
     8701 cttccacttc cagaagatac ggagtaggta cttgctgtat ttgcgacact agcataatgg
     8761 ctcatttgcg cgcttgaatg ataaaacata ctgtgccagc cataagctac atagagattg
     8821 atatctggat tttcaacttg aatctgatga accttcatca aatgactaac cttgtccgca
     8881 tagccaaata aggttgcata gaccaagaga cgattccaaa caacaatact ttccaattca
     8941 gccttatcca gtcgtgcaat ctcacgtaac atattttcaa aactggtcca gagatagtag
     9001 acctcagctc ccgcttcatt tagaacacca tcacgattat ctagtcgaag cttccaataa
     9061 tagaaaacag acaaaactaa ccctagaaaa ccaagtattg gcaaagggag gtaaagatag
     9121 ccatgaacgt ctaaactgta caagaacaaa ccaaatccga taaatagggg caagatagtc
     9181 aagacaccca tacccacttg caaagccttt tccaaaccag ttaaaggacg atagtaatct
     9241 gggagccccc agaaggaaac tcgttttctc actccttctt gcatctggtt caatacctct
     9301 tcaaaagaag atttgagttg aagccctctt gcttgaatcc gtttttcatc agaaactttg
     9361 gctctacgat aaagactatc agataccttg taatccgcaa acaaattgga aagagtttct
     9421 tcttttttac ctgaaaaagc tagatttagg cagtctttct caaagcttga caaaccatct
     9481 tcttttacta gcctcaaacc aactgcatct ccttctgaaa tgatagagac attcccacgg
     9541 tctatcacat ctagcaaggt agcttgaata agttgatcaa aggtgaattt tccagctccc
     9601 ttgaccaagg gactcacttc ctccaaggag gtcgagtaga ctgcttctga taaaaccata
     9661 ggctctaatt ccattggggg ttcatagaga cgatgatttt tagcatattt gattgaagga
     9721 gcggtctttc ttctatagat aaaatagaaa cagatgctca ataacaagga gatggaaagg
     9781 atcgaaggga agatccaagt aagtagttgt ttactttgat ctttttcttt aacgatcgaa
     9841 tcctctatct tattaaactc ttctaaacga ttccctttca agccctgatc cctagcgcta
     9901 gcaaaatcag ttcgcggcca gtaggcatgc aattcaactc cacgcttagc cggaagattg
     9961 tctaaacgaa tagtataatc aaggttactc ttttcaaccg ttctctctct aaaaagtttc
    10021 cctgtatgga aaaagagttt ctcagccccc ttgtctcccc ttacatgaaa ttcaaacttt
    10081 tcaatagact ctgaactatc tgtcagaggt tgccaattta attcagcgat atcatcataa
    10141 aggaaaagta aattttttaa gttccagacg aggtcaactt caactatgtc gccctcctga
    10201 cctggattat agactctcac agtataacca tccgcttctt ctgttacttc gctagtcaca
    10261 tctgctagtt ctgcaccgtt tttcgcggcc tgaatctttg gatgagggtc aatgtcaaac
    10321 ccgctaggca tcttaccagc acgtccaagt cccacgattt ggcccttaaa gtcctcctca
    10381 aactggtaaa ctatcttctg tctaaactct gccgtattgt ctgcatgaat atacaaatcc
    10441 ccttgataag agtttatctt gaaatcaatg gcaaaaacag agagtggaag aaggcaaaac
    10501 aagcctaaca ccagtaagaa aaaagttttt ttcatcaact aagccccctt tttatctttc
    10561 ttatcattat agcatttttt cgtaagtaaa ggcttactta tgttgaaaaa ttacgcattt
    10621 ttcgataaaa taggagacag ttatttttta atagatcaga ataggagaaa tcatgagaaa
    10681 aatatactta tctattttca caagtctctt gctgatgcta ggacttgtca atgttgctca
    10741 agccgatgaa tatttacgca tcggtatgga agcagcatat gctcccttta actggaccca
    10801 ggatgatgat agcaacggag ctgtcaaaat cgatgggacc aatcagtatg ccaacggata
    10861 cgatgttcaa atcgccaaga aaatcgctaa ggacttaggt aaagaacctt tggttgttaa
    10921 aaccaagtgg gaaggtctag tccctgccct tacttctggt aagattgaca tgattatcgc
    10981 aggtatgagt ccaactgcag aacgcaaaca agaaattacc ttttcgagca gttactatac
    11041 tagcgaacca gttttgcttg tcaaaaaaga ttctgcctac gcaagtgcta aatctttgga
    11101 tgactttaac ggtgcaaaaa tcacttctca acaaggggtc tacctttata acttgattgc
    11161 acaaatccca ggtgctaaaa aagaaacagc catgggagac ttcgctcaaa tgcgacaagc
    11221 tcttgaggct ggtgtcattg atgcttatgt ttctgaacgt ccagaagcac tgactgctga
    11281 agctgcgaac tctaagttca agatgattca agtagaacct ggtttcaaaa ctggggaaga
    11341 agatacagct atcgctattg ggcttcgtaa aaatgacaat cgtattagcc aaatcaatgc
    11401 cagcattgaa accatttcaa aagatgacca agttgccttg atggatcgta tgatcaagga
    11461 acaacctgcc gaagctacaa caactgaaga gactagcagt agtttcttta gccaagttgc
    11521 taaaattctt tctgaaaact ggcaacaact cttgcgtggt gctggtatca ctcttttaat
    11581 ctctatcgtc ggaaccatca taggtctcat tattggactt gccattggtg tcttccgtac
    11641 tgctcctctc tctgaaaaca aagtcattta cggcctacaa aaactagtcg gctgggttct
    11701 caatgtctac attgaaattt tccgtggtac gccaatgatt gttcaatcga tggttatcta
    11761 ctatggaact gcccaagctt tcgggatcaa ccttgaccgt acactggctg ctatcttcat
    11821 cgtttcaatc aataccggtg cctacatgac tgaaatcgtc cgtggtggta tcctagcagt
    11881 tgacaaggga caatttgaag ctgcgactgc tcttggtatg acccataacc agaccatgcg
    11941 taagattgtc ctacctcagg tagtccgtaa catcctacct gcaactggta atgaatttgt
    12001 catcaatatc aaagatacat ctgtattgaa cgttatctct gttgtcgaac tttatttctc
    12061 aggaaatacc gtggcaacac aaacctatca atacttccag acatttacaa tcatcgccgt
    12121 gatttacttt gtcctcacct tcaccgtaac acgtatccta cgctttatcg agcgcagaat
    12181 ggacatggat acctacacta caggtgctaa ccaaatgcaa acggaggatt tgaaataatg
    12241 acacaagcaa tccttgaaat taaacacctc aaaaaatcct atggacaaaa cgaagtgcta
    12301 aaagacattt cactcactgt ccacaaggga gaggtcatct ctatcatcgg aagctctgga
    12361 agcggaaaat cgaccttcct acgctccatt aacctacttg aaacaccaac tgatggacaa
    12421 atcctttatc atggacaaaa cgtcctcgaa aaaggctatg acctcacgca ataccgtgaa
    12481 aagttgggga tggttttcca atcctttaac ctctttgaaa atctcaatgt tcttgaaaac
    12541 acaatcgtcg ctcagacaac tgtcctaaaa cgcgaacgca cagaagctga aaagattgcc
    12601 aaagaaaacc tggaaaaggt cggcatggga gaacgctact ggcaagccaa accaaaacaa
    12661 ctctcaggtg gtcaaaaaca acgtgtggcc atcgctcgtg ccctctccat gaatccggac
    12721 gctattctct ttgatgaacc aacatcagct ctcgatccag aaatggttgg agaagtcctc
    12781 aaaatcatgc aggacctggc tcaggaaggc ttgaccatga ttgtcgtaac ccatgaaatg
    12841 gaatttgccc gtgatgtctc tcaccgtgtt atctttatgg ataagggcgt gatcgctgaa
    12901 gaaggtaaac cagaagacct cttcaccaat cctaaagaag accgaacaaa agagttcctt
    12961 caacgctatc tcaaataaaa agaaaaggct gcatcaaccg tgcagtcttt ttgctgtcct
    13021 caaaatgaaa aggcagattc tctatctcta ctacttgaag gtcaagaatc cgccgttatc
    13081 caaagattaa tcttcaaatt tttcataatt tttttcatag aaatcaatta ggcctagggc
    13141 tgtttcaaat gaaatatttt ttacttttgc acgaccctgc gccagagcaa tgatagacat
    13201 ttcacgcgca ttcgtttctt tagagatacg gtagcctgtg attttcttat cacgaaccca
    13261 gccaacaact gattctactt tttcaaagtt tgacttagcc atgtttttct cctattttct
    13321 tctttataat atttaattgt atacgttttt actacttttg tcaataaaaa aaacatatat
    13381 tcaacgaaaa taattagttc agaattttct tacttccttt ttaaatccga taatatatag
    13441 gttttgctag cctctacacc ataaatattt gctaataaaa atactgtatt attaccctct
    13501 taaggtgcga aattattcaa gttcttaaaa aatgcttctc tatttccgta agatagctta
    13561 tttcttcgat ttaagaactg aagatgatag ttctaacctt tagaaatcca agccttcact
    13621 agctcaaaaa ctcctatctt tcttcctcaa taaatcatct gagagatagg tattccttat
    13681 gtccttaaaa ttcatcactc ctttggatat tgaggtgcta gcctagaagc agacacccga
    13741 ttatctaaac catccttaat agagatgaca agacagataa gctcagttaa ttacttatat
    13801 atctttttaa tatggtatat ttgtcaacaa aaagaaatca aatcatacct tatactcaat
    13861 gaaaatcaaa gagcaaacta ggaagctagc cgcaagttgc tcaaaacact gttttgaggt
    13921 tgcagataga gctaacgtgg tttgaagaga ttttcgaaga gtattaaaga cagtgtgact
    13981 atgcttgtca atagatagga aatcaaaatg aaggatggaa atctgagcca aacatcataa
    14041 gtgctataat gaacagaagt aagaattgca cgataagttt tctaaaacca taggaatcgt
    14101 cccctttctt catcttcatt atagcacata tacatcagtt gtacaaataa tatgatattt
    14161 ttttattagt cctcagacaa gcatattata aagcgtttca ttaccattta agttaatata
    14221 agctggatca aaaccttcca ttctacgaat caaacctgca taatcatgct tatctgctaa
    14281 agcgatccca attaatactg ggcctgttcc cttgctagct cgtttgatat actcaaaacg
    14341 tgtgatatca tcatttggcc ccaggatatc atttacaaac tcacgcaaag ctcctggacg
    14401 ttgtgggaaa ttgaccacaa agtaatgttt gataccatca taaatcaagg cacgctcttc
    14461 catttctggc atacggttga tatcattatt tcctccagaa atgatacaac aaatggtttt
    14521 ccccttaata tattcagcta aaacctctaa agaggcgata ctagccgctc cagcaggttc
    14581 tgcgactatc ccttgcttag agtaaaggtc aatcaaggtt tcagaaatca atccctcatc
    14641 gacacctacc aaagttttaa tatgttgacg agttgcttca taggtcaact gacctacctt
    14701 ttgcacagca atcccatcag caaatttatc aatttccttg agtttgactg gacctccagc
    14761 ctcaaaggca gctttcatgg aacgcgctcc attcgcctct actccgataa cctcaatctc
    14821 tggacttgtt tccttgatat aggtagaaac cccggcaatg agaccgccac caccaacagg
    14881 aaccaagaca gcatcaaaat caatcgattc ttttcgagct tcttctaaaa tctcataagc
    14941 aactgttcct tgacctgctt gaacatgagc atcatcaaaa ggatcaataa aggtacgatt
    15001 ttcagagact gtaaattctt gagctgcttt ggctgaggca tcaaaggtat ctccaactag
    15061 tttaatagtt acaaaatccc caccaaaaaa gcgaacctga ccaatctttt gttgtggcgt
    15121 agtaatgggc ataaagatag tagcaggaat tttcatttca ttacaagtat aggctactcc
    15181 ctgcgcatga tttcccgcag aagcgcagac taccccacgt tcacgttctt ccttgctgag
    15241 ctgggaaatg gcataatagg caccacgaat tttaaaggag cgaacacgct gggcattttc
    15301 ttttttcaaa taaatcttag caccatactt ctccgataaa taatgatcgt aatccagtgg
    15361 agtattcaca accacaccgt tcaagacctt gtgagccttg attatatctt ttgaacttaa
    15421 catataaaac ctctttttct ataaaaaaca gtcactaatg actgtttttt agttattcat
    15481 ctccgaaaac ttcagtaaca ctttcatggt atttatgagc catacgaatc gaaaactctt
    15541 taggaagttc ataacgattt gtggaaatcc aatcatataa ccattctacc aaactttctt
    15601 cactatcatt acgatggaag ataaaatagt ttaaaatttc tttatattct acatcattca
    15661 aatccaacgt gtctacaaat tgactacgag gaacaaaatt agaatctaat tttcttagtt
    15721 gatctgtcaa ttctcccaat tgtaaatcca actgaaaaaa tagtttttgc agttgcctat
    15781 cagtttcatc acatcctgtc ttgatagaaa acaaattggt aatattcata tgatttcaac
    15841 ccctaaataa gtacatctaa tatcccacga atagctgaag ctaaagtttt cgcagtccag
    15901 tcatttaaac ccgattcttt caatccagat gcaataattt gctctatttg atataaatcg
    15961 ccatctatcg tctcatttat tctgcgaaga ggaccttcaa tataggataa agcttctccg
    16021 aatctaacag ctgatttagg tcctaatgat ttaccaacta tatttgttaa tgttttttat
    16081 ttctcaaaat ccatttcgct atataacgag cagatttagt cgcatcagct ctctcaaacg
    16141 gagaatgaat ttcaagacct tcttctctag ctatttgtgc caatttgaag aattgttcaa
    16201 aggtcatatg caacctacca tcttcaaaat tagcatcatc ataaatgtta attacagcat
    16261 tttcatcata cgaccaatct gctttatttt ggtctgctag cactattacc gacggtgtaa
    16321 ttacattata caactagaac caataataac gatgcaattt ttctcataat ctttttcata
    16381 aaatcatctc cagcgctata tatttctaat tagttataga ttttgaatgc atcatcgtcg
    16441 tttttaccaa cgaatggcat tgctttacgc aattctgcac caactttttc aatttcaagg
    16501 ttagctgctt gttcacggta agcagtcaat tttggacgtc cagctttata gtcatttaca
    16561 aagtcatttg caaacttacc attttggatg tctgccaaga cagccttcat attttcttta
    16621 acttgttcag tgattacacg tggacctgat acatagtcac cgtattcagc agtgtttgaa
    16681 atagactgac gcattttctt gaatccacct tcgtagatca agtcaacgat caatttcatt
    16741 tcgtgaagaa cttcaaagta agccaattct ggagcgtaac ctgcttctgt caagacttcg
    16801 aaacctgctt cgataagggc agtcaaacca ccacaaagta cagcttgttc accaaacaaa
    16861 tcttcttcag tttcttcttt gtaagttgtt tcaagaagac ctacacgagc cgctccaaca
    16921 cctttacacc agtccatagc aatgttttta gcatttcctg ttgcatcttg gtatactgca
    16981 taaagagctg gaacaccaaa tccttcttcg taagtacgac gtaccaagtg tcctggtcct
    17041 ttaggagcac acatgaagac atctacatcc gcaggaactt tgataaattc aaagtggatg
    17101 ttgaaaccat gggcaaatcc aactgcgttt ccagcttcca agtttggagc gatttctgct
    17161 tcgtacaatt cttgttgaat ttcgtctggc gccaagatca tgataacatc agccaactta
    17221 gtagcttctg ctactgtgta agtatcaaat ccatcttctt ttgctttatc aaaagattta
    17281 cctggacgta caccgataat aacgtcacga ccggaatcac gcaagttttg agcatgcgca
    17341 tgcccttgtg aaccataacc gataacggcg atttttttac cgtcaagtgc tgctacttta
    17401 acatcttttt catattccat ttgaactgtc atagcttttc tctcttttct attatttatt
    17461 gccttttagg ctggtttaat aaatttaagt tggattttta atcgcgggta aatccagttg
    17521 cacccgttcg agcaatattg cgaataccgt atgggcgaat gactcgcaat agggcttcgc
    17581 tcttttctgc atttcccgtc atctgaatgg taatcgagct tggcgctacg tctaccactg
    17641 ttgcacggaa aggttgaata atcgctaaaa tctcagctct cttctcagct ggcgctgaca
    17701 tcttaaccaa aatcacctcg cgctccaaat gaggcttgtc tgtaatatct cgaatgcgaa
    17761 tcacatcaat ctgacgattg agctgtttga tgatttgctc cacttcatca tgagaagcaa
    17821 catcaataat aatagtgata cgcgatacat tcggatcttc tgttgctcca acagagatgc
    17881 tttcaatatt aacctgacga cgagatagga cacctgtaaa gcgattgagt actcctgaac
    17941 gattttgtag ttttgctgtt aacattctac gcatggaact tcacccccaa catctcatga
    18001 ttactcttac cagccggtac cattggtaac acctgttcct tacgagaaat atctacctca
    18061 attagcatag gaacatcctc agtgatgact tcaaggtctt gagccaaggt ctcaggattg
    18121 tcaaacttat agtttttaat accataagcc tgcgccatca attggaaatc aggaagggta
    18181 tcaaagaccg actctgatgt tctgccttca tagaaggatt cctgccactg gcgaaccatt
    18241 ccaagtgaat gattgttcag cataaccacc ttgattggca ccttgtaaat attcaaaata
    18301 gccaactcct ggttggtcat ttggaaacca ccatccccaa caaacaagac tacttcctta
    18361 tctgggttag caattttagc accgattgct gctggaattc caaagcccat tgttcccaaa
    18421 ccacctgaag tcactaactg acgctcattt tggtagggat aatactgagc tgtccacatt
    18481 tggtgttgac caacgtctgt taccacaatg gcatctccat tcgtcaattc accaattcgt
    18541 tcaataactg cttgcggttg aaccacacgc tctttcttgt cataagaacg aacacgattc
    18601 ttgtctttag tgactttctc aatccacttt tcagtattgt tgtgaactgt tggttctgct
    18661 agcaacattt gcaaggcctt cttagcatct ccaactacag gaatgtctgc actgataatc
    18721 ttgccaatct cagctgggtc aatatcaatg tgggcaacct tagcattctt agcgaaagtc
    18781 ttaggattcc ccgtcaaacg gtcatcgaaa cgagaaccaa tactaatcat aaagtccgct
    18841 tccgtcatgg caatatttgc tgcgaatgac ccgtgcatgc ctcccattcc aagaaagagt
    18901 gggtgactcg ttgcaatcgt tccttgtccc aaaagactgg ttaccactgg aatttgatag
    18961 cgttctgcaa attcatttag ttccgtagca gcctcagcat aactaattcc accaccagct
    19021 aacaagactg gctttttagc cttggacaat tgcttcaaga ttttcttgat ttgcatatca
    19081 ttcggctcaa gagtcggctg ataacttggt aaattcactt ctggtgaata aatgaagtct
    19141 gtttctaaag cagatatgtc ttttggtagg tcaattacaa ctggccctgg acggcctgta
    19201 gttgcgatat ggacagcttc cgtaatgata cgcggaatat cagctgtctc acgaacttgg
    19261 taattgtact tagtgattgg catggtaatt cccacgatgt ctgcctcctg aaaggcatcc
    19321 ttcccaatcc ctgctcgcgc cacctgacct gtaaagacca aaaggggaac gctatcgctc
    19381 atggcatccg caatccctgt aatggcattt gttgctcctg gtccactagt gacgacggca
    19441 acacccaact ttccagttga tttggcataa ccttcagctt catgcaaaca accttgctca
    19501 tggcgcccta gaatgtggcg aatgccttta aaattatata tcgcatcata aaaaggcaaa
    19561 accgcaccac caggataacc aaagatggta tcaactccta aatcacgaag tgtttccaaa
    19621 actaggtccg accccgtctt aggagattct aaactgattt tctccattat tcccctttct
    19681 ttcctcttaa aaataacttg ttactatcat accatttttt caaaattttt caagataaaa
    19741 gaagaaattt tctgaatttt ctattttaac gtttatttat gaatgttatt tttgttttta
    19801 ttaaaaagat accgatttca tttactaaaa aagaaaaaag aactgatttc tcagtccttc
    19861 attaatctta ttccacacta aataggtatg ggtaaacagg ttgttgacct tggtgaatct
    19921 cgacttcaac gtcttcgaat tcttctacga tttcttgagc gatttcattg gcaagttctt
    19981 cgcttccgtc ttcaccgaca tagaaggtta cgatttcact gtcttcatcc aacatatgtt
    20041 tcaaggtttc agtcaatgtt tggtgcatat cagggtttga cacaagaatt tttccatcca
    20101 ccatacctag attatcgttt tcatggattt ctaagccatc gatcgttgta tcacgcacgg
    20161 ctgttgtgac gcttccgcta acaacatcgc taagagcagc tgtcatacgc tcttggtttt
    20221 cttcaatgga cttgcttgga tcaaaggcaa gaagacttgt cataccttga ggaagagtgc
    20281 gagcctctac cactactgct ggttgctcca aaacttctgc cgcagattga gctgccatga
    20341 agatgttctt gttgtttggc aagaagatga tgttacgggc attgacctgt tcaacagcct
    20401 tgataaagtc ttctgttgaa gggttcatgg tttgaccgcc ttcgataaca taatccacgc
    20461 cttgagaaca gaagatatct gctagacctt taccagccac cacagcaatc aaagcatact
    20521 ctttttcttc agccgacttg ataacttgag tagcttcttt ctcaacctgt gcttcgtgtt
    20581 ggttacgcat attgtcaact tttaccttga ccaagctacc atatttgaga ccttcttgca
    20641 taacaagtcc tggatcttct gtatgaacat ggactttgac aatttcatca tcgttaacaa
    20701 cgaggagaga atccccaagc tcatccaagt agttacggaa ttcatcgtag tcaaaatctt
    20761 tagcataggt tggaccttgc ttaagagcta ccatgatttc agtacagtaa ccaaacgtga
    20821 tgtcctcagt cgctacgtga ccagctacag acttatgatg ctctacattg atcatctcac
    20881 tcatgttggc aggagtcgct acaaagtcct cagatgcaat atattcgcca gtaagggctg
    20941 aaaggaaacc ttcgtagatg aagaccaatc cttgaccacc tgagtccaca acgccaactt
    21001 ctttcaatac tggaagcatg tctggtgttt tagctagagc tgttttagca ccttccaagg
    21061 ctgcgcgcat gacttcaaca gcgtcatctg tttgctcagc ttttttctta gcaccgatag
    21121 cagctccacg agaaactgtt aaaatcgttc cttcaacagg tttcatcact gccttatagg
    21181 caacttccac acctgattgg aaggccagag ccaagtcttg acctgttaac tcgtctttat
    21241 ccttgatagc ttgggaaaat ccacggaaaa gctgagacgt aatcactcct gagttcccac
    21301 gcgcacccat caaaagccct ttggcaagaa tgctcgctac ttctccaact gtagaagctg
    21361 gcttgtctgc aacttcttta gcaccatttt caatggtcat tcccatattt gtcccagtat
    21421 ctccatctgg gactggaaag acgtttaatg aattgacata ttcagcttgc ttattcaagc
    21481 gagttgatgc agcctgcacc atttcttgaa ataagctagt agtaattttt gacacggtta
    21541 ttctcctaca actttgatat tttgaatgta gacatttaca gtctgagcag taattccaag
    21601 ctggttttcc aagctaaagg caacacgctc ttgaatgttt tttgacactt cactaatctt
    21661 tgttccgtag cttaacacgg tatatacatc aactgcaata ctgccatctt cggctgcctt
    21721 tacgacgaca cctttagaat aattttcctt acctagcagg gcttggaaat tatctttgag
    21781 ggcattttta ctagccatac cgaccacacc aaaaatctca gttgctgctc cacctacgac
    21841 ggttgcaatc acttcatctg ttagttcgat ttgaccatct tttgtattaa tttttacagt
    21901 catccttttt acctcaacta gttgatactc tattttatca tatttcagcc caagtgtaaa
    21961 agcagaatga tgtatcagcg gatatttact ctatttttca aacgatgtta tacccacaat
    22021 aaaagaaaaa agaccctaag gtctcctttg cttttattat taaacgcgtt caactttacc
    22081 tgatttcaaa gcacgagctg aagcccaaac ttttttaggt ttaccatcga taagaacagt
    22141 aactttttga aggtttggtt ttacggcacg ttttgtttgg ttcatcgcgt gtgaacggtt
    22201 gtttcctgat acagtcttac gacctgtaaa gtaacatact ttagccattg tgttttcctc
    22261 ctattagatc taatatagcg gatgtgctag caccacatac cgtactatgt tatcacactt
    22321 tcttgttttt tgcaagggaa ttggaagatt ttttatttgt gtcttaaatc aggtcttgcg
    22381 tgacattttc tgctctccac atgccattgt tgattaacag aacaccagaa ttaaaattat
    22441 gtgtataaaa atcatctcta actgcagcta agggtatagc cgtcaagtcc aaatcccaca
    22501 gctcatctat cgattttctt acaacaatat ctgaatccaa atacagtaca cgagactcgc
    22561 ttacatactt tggaataaaa tacctaaaaa aagccgcata tgaaagtccc tcaaagggga
    22621 gacgataacc tttcagaata ctactgtcaa tctgaacatt cacaatctca ctattcaaag
    22681 tctctagtct tttttccatc aattggaacc attctcgcgg aaggtcatca ttaaaaacat
    22741 aaaacttaag attataatga tgaacacaaa gagattttat tgttgtttca actttatcca
    22801 tataagcatt atctgcacct aagacaatcg cttttttctc ttctttcact ctttatctta
    22861 tttcttttta ttcccatcat attattccca tcatatgttt ctacgtaacc attattttcg
    22921 cctattcgtt cgtaaaacca taccagtgga gattttagat gaagtcccat tacggtttac
    22981 attttttaca ttacgacacg gagttttaca aatcgatttc atttgccaaa cgtagttagt
    23041 gaggcagtta gctagttcgc caaatagcga ctagcgtcca acaatttgga actttagttc
    23101 caattgttgg tactgagtca catcttctcc tctaactcta cgtctggata cttgtccgca
    23161 aaccagcgga gggcaaagtc attttcaaag agaaagactg gttggtcaaa acggtctttg
    23221 gctaagatat tgcgacttga cgacatccgt tcatccaagt cctcaggctt gatccaacga
    23281 acggtctttt tacccattgg gttcataact acttccgcat tgtactcgct ttccatgcgg
    23341 tgtttaaaga cttcaaactg gagttgacct acagcgccta gcatgtactc acctgtttgg
    23401 taattcttat aaagctgaac ggctccttct tgcaccaatt gctcaatccc cttgtggaag
    23461 gatttttgct tcataacatt cttagcagaa actttcatga aaatttcagg agtaaaggtt
    23521 ggcagtggtt caaattcaaa cttgtttttt ccaaccgtca aggtatcccc aacctgataa
    23581 gtaccggtat cgtaaacccc gataatatca cctgccacgg cattggtcac attctcacga
    23641 ctctccgcca taaactgggt aacattagat agtttggcac ccttaccagt acgagggaga
    23701 ttgacactca tgccacgctc aaattcgcct gatacgatac ggacaaaggc aatacggtca
    23761 cggtgacgag gatccatgtt ggcttggatt ttaaagacaa agcctgagaa atccttgtca
    23821 taaggatcca caatttcacc gtctgttttc ttgtgaccat gtggttctgg agcaaacttg
    23881 aggaagattt caaggaaggt ctgcacacca aagtttgtca gggctgaacc gaaaaagaca
    23941 ggcgtcaatt ctccagccag aatagcttcc tctgaaaact cattcccagc ttcatttaaa
    24001 agctcaatgt catccttgac ttgctcgtag aaaggattgc taccaaaaag tttgtctcca
    24061 tcttctaggc tagcaaaacg ctcatcccct ttgtaaagct ctaaacgttg gttatagagg
    24121 tcatacaagc cctcaaaggc tttccccatc ccgataggcc agttcatagg gtagctagca
    24181 atgcccaaga tttcttccaa ttcttgcaag agatccaaag gctcacgacc gtcacgatcc
    24241 aacttgttca taaaggtaaa gactggaatg ccacgatgtt tcacaacctc aaacaatttc
    24301 tttgtttgag cctcgatccc cttggcagag tccacgacca tgaccgcagc atccaccgcc
    24361 atcaaggtac gataggtatc ttctgagaag tcctcgtgcc ctggcgtgtc taagatattc
    24421 acgcgcttgc cgtcgtagtc aaattgcata acagatgaag taacagaaat cccacgttgc
    24481 ttctcgatat ccatccagtc agatttagca aaagtccctg ttttcttccc ttttaccgta
    24541 ccagcatcac gaatctcacc cccaaagtag agtaactgct cagtgatggt tgttttcccc
    24601 gcgtccgggt gggagataat ggcaaaggta cgacgtttct taatttcttc ttgaatattc
    24661 ataagttctc tttctttgat tctctatttt tcttgtttca atagctgaga atgattttta
    24721 cattggattt taccattcct ttcgacactc cattatatcg gattttagca tttttttcaa
    24781 tttctatttc ttttcacttc cccctccctt atttatagga aaatatggta aaatagaaca
    24841 gactaaaaat catcatttca cgaaaggatg caagatgaaa attacgcaag aagaggtaac
    24901 acacgttgcc aatctttcaa aattaagatt ctctgaaaaa gaaactgctg cctttgcgac
    24961 caccttgtct aagattgttg acatggttga attgctgggc gaagttgaca caactggtgt
    25021 cgcacctact acgactatgg ctgaccgcaa gactgtactc cgccctgatg tggccgaaga
    25081 aggaacagac cgtgatcgct tgtttaaaaa cgtacctgaa caagacaact actatatcaa
    25141 ggtgccagct atcctagacg atggaggaga tgcctaatga cttttaacaa taaaactatt
    25201 gaagagttgc acaatctcct tgtctctaag gaaatttctg caacagaatt gacccaagca
    25261 acacttgaaa atatcaagtc tcgtgaggaa gccctcaatt catttgtcac catcgctgag
    25321 gagcaagctc ttgttcaagc taaagccatt gatgaagctg gaattgatgc tgacaatgtc
    25381 ctttcaggaa ttccacttgc tgttaaggat aacatctcta cagacggtat tctcacaact
    25441 gctgcctcaa aaatgctcta caactatgag ccaatctttg atgcgacagc tgttgccaat
    25501 gcaaaaacca aaggcatgat tgtcgttgga aagaccaaca tggacgaatt tgctatgggt
    25561 ggttcaggtg aaacttcaca ctacggagca actaaaaacg cttgggacca cagcaaggtt
    25621 cctggtgggt catcaagtgg ttctgccgca gctgtagcct caggacaagt tcgcttatca
    25681 cttggttctg atactggtgg ttccatccgc caacctgctg ccttcaacgg aatcgttggt
    25741 ctcaaaccaa cctacggaac agtttcacgt ttcggtctca ttgcctttgg tagctcatta
    25801 gaccagattg gaccttttgc tcctactgtt aaggaaaatg ccctcttgct caacgctatt
    25861 gccagcgaag atgctaaaga ctctacttct gctcctgtcc gcatcgccga ctttacttca
    25921 aaaatcggcc aagacatcaa gggtatgaaa atcgctttgc ctaaggaata cctcggtgaa
    25981 ggaattaacc cagaggttaa ggaaaccatt ctaaatgccg ctaaacactt tgaaaaattg
    26041 ggtgctattg tcgaagaagt cagccttcct cactctaaat acggagttgc cgtatactac
    26101 atcatcgctt catcagaagc ttcatcaaac ttgcaacgct tcgacggtat ccgttacggc
    26161 tatcgcgcag aagatgcaac caaccttgat gaaatctatg taaacagccg aagccaaggt
    26221 tttggtgaag aagtgaagcg ccgtatcatg ctgggtactt tcagtctttc atcaggttac
    26281 tacgatgcct actataagaa ggctggacag gtccgtacac ttatcattca agatttcgaa
    26341 aaagtcttcg cggattacga tttgattttg ggtccaactg ctccaagtgt tgcctatgac
    26401 ttggattctc tcaaccatga cccagttgcc atgtacttag ccgacctatt gaccatacct
    26461 gtaaacttgg caggactgcc tggaatttcg attcctgctg gattctctca aggtctacct
    26521 gtcggactcc aattgattgg tcccaagtac tctgaggaaa ccatttacca agctgctgct
    26581 gcttttgaag caacaacaga ctaccacaaa caacaacccg tgatttttgg aggtgacaac
    26641 taatgaactt tgaaacagtc atcggacttg aagtccacgt agagctcaac accaattcaa
    26701 aaatcttctc acctacttct gcccactttg gaaatgacca aaatgccaac actaacgtga
    26761 ttgactggtc tttcccagga gttctaccag ttctcaataa aggggttgtt gatgccggta
    26821 tcaaggctgc tcttgccctc aacatggaca tccacaaaaa gatgcacttt gaccgcaaga
    26881 actacttcta tcctgataac cccaaagcct accaaatttc tcaatttgat gaaccaatcg
    26941 gatataatgg ctggattgaa gtcaaactag aagacggtac gaccaagaaa atcggtatcg
    27001 aacgtgccca cctagaggaa gacgctggta aaaacaccca tggtacagat ggctactctt
    27061 atgttgacct caaccgccaa ggggttccct tgattgagat tgtatctgag gcagatatgc
    27121 gttctcctga agaagcctat gcttatctga cagccctcaa ggaagttatc cagtacgctg
    27181 gcatttctga cgttaagatg gaggaaggtt cgatgcgtgt ggatgccaac atctcccttc
    27241 gtccttatgg tcaagagaaa ttcggtacca agactgaatt gaagaacctc aactccttct
    27301 caaacgttcg caaggggctt gaatacgaaa tccaacgtca agctgaaata cttcgctcag
    27361 gtggtcaaat tcgccaagaa acacgccgtt acgatgaagc taacaaaaca accatcctca
    27421 tgcgtgtcaa ggaaggggct gcagactacc gctacttccc agaaccagac ctacccctct
    27481 ttgaaatttc tgacgagtgg attgaggaaa tgcggactga gttgccagag tttccaaaag
    27541 aacgtcgtgc gcgttatgta tctgaccttg gtttatcaga ctacgatgct aatcagttga
    27601 ctgctaataa agtcacttct gacttctttg aaaaagctgt tgccctaggt ggtgatgcca
    27661 aacaagtctc taactggctc caaggggaag tcgctcagtt cttgaatgct gaaggtaaaa
    27721 cactggaaca aatcgaattg acaccagaaa acttggttga aatgattacc atcatcgaag
    27781 acggtactat ttcatctaag attgccaaga aagtctttgt ccatctagct aaaaatggcg
    27841 gtggcgcgcg tgaatacgtg gaaaaagcag gtatggttca aatttcagat ccagctatct
    27901 tgatcccaat catccaccaa gtctttgccg ataacgaagc tgctgttgcc gacttcaagt
    27961 caggcaaacg taacgccgac aaggccttta caggattcct tatgaaggca accaaaggcc
    28021 aagccaaccc acaagttgcc cttaaactac ttgcacagga attggcgaag ttgaaagaaa
    28081 actagacaga acaaaaccag ccctaaggtt ggttttttct tgacaaatag aaagaaaacg
    28141 tttacaatat tgcgtgtaaa gtttccaaac aagaaaacta aaaatcgcaa caataaggag
    28201 ttatttatat ggctacaatg aaggcagctc gctggcatgc agcgaaagat gttcgtattc
    28261 aagaaataga agttcctgaa gtacttccgc accaagtaaa agttgcagtt aagttcacag
    28321 gaatttgtgg tactgacctc catgaatttt tagatggacc tatctttatc ccaacagatg
    28381 agcacgtcta ttctggtcaa aaagcaccgg taacactggg acatgaattt tctggtgaaa
    28441 tcatagaagt cggaagcgat gttacccgtg ttaaagttgg tgatcgtgtt gctgtggaac
    28501 caattctagc taaaaataac ttagttggtg attataattt ggatccaaac cttaattttg
    28561 tcggtttggc tgcagacggt ggatttgcca aatattgtgt tttagacggt gacttagtac
    28621 atgtcattcc agatagcttg agctatgaac aagctgctct tactgaaccc gctgctgttg
    28681 cagtctatgc tgttcgtcaa tcttctttga aggctggcga tacagctgtt gtctttggtt
    28741 taggcccgat tggtctatta attgtagaag ctcttcgtgc agctggtgct tctaagattt
    28801 atgctgttga actatcacct gaacgtcaag caaaagctga agagttagga gctatcgttg
    28861 tccgtccgga agaaggtgaa acagctgttg aagctattca tcgtttaaca aacggtggtg
    28921 tagatgtttc ttatgaagta acgggtgtgc cagtagtttt aggacaagcc ttagctgccg
    28981 tacataaagc aggtgagtgc atggtggtct ctatctggga acgagaagca aatattaatc
    29041 cgaatgaatt tgcaatccaa gaaaagacac taaaaggaat catcgcttat cgtcatatct
    29101 tccctaaagt attagaattg atggaacaag gctacttctc tgctgaaaaa ttagttacta
    29161 agaaaattaa attggaaaat atcgtcgaag aaggctttat cgaattaact caagataagt
    29221 cacaaattaa aattttggta gaaccagaat aaaaaatcaa tctttttaag acaatactaa
    29281 caggtcggag taaacttact tcggcctttt gaaatataat actcttcgaa aatctcttca
    29341 aaccacgtca gcgtcacatt accgtatata tggttactga cttcgtcagt tctatccaca
    29401 acctcaaaac agtgttttga gcagcctgcg gctagcttcc tagtttgctc tttgatttcc
    29461 attgagtatg agaagaaata tagtggatac tctttaacat taaccactcc acctgactag
    29521 ccaatattct ttttcgctcc taccaactcc caataactat tttggcttta tttccagagt
    29581 attttatggt aaaatgaaga gtaataatat ttgttaaaga ggtaaaaaca tgattgaagc
    29641 aagtaaatta aaagctggta tgacctttga aacagctgac ggcaaattga ttcgcgtttt
    29701 ggaagctagt caccacaaac caggtaaagg aaacacgatc atgcgtatga aattgcgtga
    29761 tgtccgtact ggttctacat ttgacacaag ctaccgtcca gaggaaaaat ttgaacaagc
    29821 tattatcgag actgtcccag ctcaatactt gtacaaaatg gatgacacag catacttcat
    29881 gaatacagaa acttacgacc agtacgaaat ccctgtagtc aatgttgaaa acgaattgct
    29941 ttacatcctt gaaaactctg atgtgaaaat ccaattctac ggaactgaag tgatcggtgt
    30001 caccgttcct actactgttg agttgacagt tgctgaaact caaccatcta tcaaaggtgc
    30061 tactgttaca ggttctggta aaccagcaac gatggaaact ggacttgtcg taaacgttcc
    30121 agacttcatc gaagcaggac aaaaactcgt tatcaacact gcagaaggaa cttacgtttc
    30181 tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt gaagaacaac ttggcgaaat
    30241 cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc gctactgcaa aggtagaggg
    30301 tgttcactct ttttcaaaca gatcagtgtc tgataccctt tcaaaacttt cactcggccg
    30361 tggcatttat cttaaaaacg tggacgaaga actcacagca gatatctatc tctaccttga
    30421 gtacggagta aaagttccta aggtagcggt tgctatccag aaagctgtca aagatgccgt
    30481 ccgtaatatg gctgatgtag aactcgctgc tatcaatatt cacgttgcag gtatcgtccc
    30541 agataaaaca ccaaaaccag aattgaaaga tctatttgac gaggacttcc tcaatgacta
    30601 gtccactatt agaatctaga cgccaactcc gtaaatgcgc ttttcaagct ctcatgagcc
    30661 ttgagttcgg tacggatgtc gaaactgctt gtcgtttcgc ctatactcat gatcgtgaag
    30721 atacggatgt acaacttcca gcctttttga tagacctcgt ttctggtgtt caagctaaaa
    30781 aggaagaact agataagcaa atcactcagc atttaaaagc aggttggacc attgaacgct
    30841 taacgctcgt ggagagaaac ctccttcgct tgggagtctt tgaaatcact tcatttgaca
    30901 ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc aaaggacttc tccgatcaaa
    30961 aatctgcccg ttttatcaat ggactgctca gccagtttgt aacagaagaa caataaaaag
    31021 aaaaagtgtt tgatagatat caaacacttt tttctttgcc tcccactatc taaaaaaatg
    31081 ataatagata taattgtaaa caaaaatcca gataggtttt gcatgattga gaaagttaaa
    31141 aaaactatgg cagagaatcg ttaatctcag attgtcggta gaacgataaa caagggcaaa
    31201 aaagaaacca atcagactat aatataataa actaattgga tctctgtgag atagtatcaa
    31261 atggctaatc ccaaagatga tagcagatag gataacatcc aaatagtact tggactaggg
    31321 aaagaaggta ttcataaaat accctctatc aagagtctcc tcaaaaacag gaccgatgat
    31381 tacaggcagg acaaaagata agatagtcga taaaaaggtt ggttgtccat ttgaaaaaag
    31441 cacggtaaaa tactcatcat gaatattcct atgattaatc aaatgagcat agcgtgccca
    31501 aaaattaccg agaatctgat aaaccacata agttgcaaat aagtagaaga caaatgacca
    31561 gttccagctc tttttctcaa agataaagag catctttttc ttttttaacc tccaaattaa
    31621 tagaaggaaa cttcccacta atcccattgt taaaataaga gaatagacat cagctcctaa
    31681 ccctaaaatg atcgtcacat acaatccaat tgtttgtggt aaataggtag atagtaaaat
    31741 aataagcaaa aatattccaa attgtcttag tttttttgtg tttctcatcg tacttttttg
    31801 aaagattacc ctgctcggaa gccgtacttc caagcatcta tataagaatt aagtgcccct
    31861 tgcctcatat agggagcaaa ttctctataa tataaccatc tactatatcc atcttcccaa
    31921 acagcaagac cacctgaagt ttgctccaag tcctcagttg aaagaactgt aaatgtattt
    31981 gtacctgtca ttgcaagtac cttcttaaaa tagattgttg taggctcaca tttatagtat
    32041 atttcttttt ttgtctattt tatagcccat ctcctcaact ggcaattttt cgacctgaat
    32101 tacatttttc cataaaaaat gagacctttc tagtctcatt tagtcattct tagtattttc
    32161 taaatcgttg atagcgttct tccagcaact cttctagcgg tttttgtgaa agtctagcca
    32221 gctctgtttg gagttctttt ttgacactct taatcagttc tttactagaa agtcctattt
    32281 cagaaatcac cttatctacc acgtccattt ctaacagttc atgcgaagtg attttcatca
    32341 gttctgctgc ttccatagcg cgagtaccgt ccttccataa aatggaagca aagccttctg
    32401 gactgagaat ggcatagata gaattttcca gcatccagac acggtccgcg acagctagag
    32461 ccagagcccc gcctgaacca ccttcaccga taataatggc gataatagga actttcaggt
    32521 cactcatttc catgagattg cgagcgatag cttccccttg accacgttct tccgctccga
    32581 caccaggata agcacctgct gtattgataa aggtcacaac tggacggcca aatttctcag
    32641 cctgtttcat caaccgcagt gcctttcggt agccttctgg atgtggttgg ccaaaattcc
    32701 gtttgaggtt gtcttgcaaa ctcttgcctt tttggatacc aaccactgtt acagcttgat
    32761 ctccaagcca accaatacca ccaacaactg caccatcatc acgaaaagaa cggtcaccat
    32821 gtaattggat aaattcatca aaaatgcctg tcgcaaagtc caaggttgtc aagcgactct
    32881 gctcacgcgc ttctctgact atttttgcaa tattcatcta ggactccctc catgcaatct
    32941 gactaggcta gcaatcgtat ctggtaagtc tcttcttttg acaatagcat ccacaaagcc
    33001 atgttctaat aggaattctg ccttttggaa atcctcaggc aagctttcac gaaccgtatt
    33061 ttcaatcaca cgacgcccag caaaaccaac caagctctgt ggttcagcca gaatgatatc
    33121 gccttccata gcgaaagaag ctgtcacacc accagtcgtt ggatctgtca aaatggtcag
    33181 gtaaaagaga ccaacatttg aatggcgttt aaccgccgca gagatcttag ccatctgcat
    33241 gagactcatg attccttcct gcatacgggc tccaccagag gctgtgaata ggacaactgg
    33301 caatttttcg acagtcgcat actcaaacaa acgagtgatt ttttcaccta caaccgtacc
    33361 catagaagcc atgataaagt tagaatccat aatcccaaga gccacagtct gacctttaat
    33421 aagagcagtt cctgtcacaa cggcttcatg cagacctgtt ttttcacgca tagatgccag
    33481 tttcttttgg taaccaggga aatgcaaggg atccttgctt tcaatccctg taaacaattc
    33541 tttgaaggtt cccatatcaa tcgtcaaagc caagcgttct tgggcagaaa tacgaaaggt
    33601 atagctacag tgcggacaga tacgttcact tcccagatcc ttctgataga tggtatgctt
    33661 acagcctgga cactgggaaa ataattcatc tggaacctct ggcttagctt gaggtttttc
    33721 cctaaccgaa cgattgggat tgattcgaat atacttatct tttttactaa atagagccat
    33781 tgattcccct tttcggttta aactcttaaa gtcattttat tctttttctt gatatttagg
    33841 taagaaggtt tccatcaaga aggaagtatc ataatcccca gcaatgacat tgcgatctga
    33901 aatgaggtca agctggaaat ctgcattggt ctgcactcct tcaatctcta attcatagag
    33961 ggcacgttgc attttcatca aggcgtcaaa acgattttcg ccgtgtacta tgattttggc
    34021 aatcatacta tcataataag gcggaatggt ataacctgga taaactgctg aatccacgcg
    34081 caaaccaact ccaccacttg gcagatagag attagtaatc ttacctggac ttggagcaaa
    34141 gttaaaggct gggttttctg cattgatacg acactcgatg gcatgaccac gtaggacaat
    34201 atcttcttgc ttaacagaca aaggctgacc tgccgcaatg caaatctgtt ccttaacgat
    34261 atcaacacct gaaacaaact ctgttactgg atgttctacc tgaacacgag tattcatctc
    34321 catgaaatag aaattgctac ttgcttcatc aagaagaaat tcaatggttc ctgcattctc
    34381 atagccaaca aactctgccg ctcgaacagc agcagcacct atttcatgac gcagcgtttt
    34441 tccgattgca atcgagggac tttcttccaa aaccttttgg ttattccttt gaagagaaca
    34501 atcccgttca cccaagtgaa tcacatgtcc atgctcatca cctaggattt gaacctcaat
    34561 gtgccgagct ggatagataa cccgttctat gtacatggca ccattgccat aattggcctt
    34621 ggcctcacta gaggcagttt caaaggcaga aacgaggtca tctggttttt caaccttacg
    34681 aatcccttta ccacctccac ctgctgaagc cttgagcata acaggatagc caattttttc
    34741 agcaacaatc aaagcttctt cagagttatg cacttctcca tctgaacctg gtataacagg
    34801 cacacctgct ttaatcatct gagcacgcgc attgatctta tcccccatca tatccataac
    34861 atgaccagat ggaccgataa acttgatacc tacttcttca cacatggtcg caaatttgga
    34921 attttcactg agaaatccaa aaccagggtg aatagcttct gcctcagtca agactgcagc
    34981 tgatagaact gcattaatat tgagataaga ctctgttgcc ttgccaggac caatacaaac
    35041 tgcttcatct gccaaaagcg tatgaagagc ttccttatca gcagttgaat aaaccgctac
    35101 cgtcgcaatc cccaattcac gtgccgcacg gataatacga accgcaattt caccacgatt
    35161 ggcaattaaa atttttcgaa acatggagaa cctccttagt tcccaattgc aaaagtaagg
    35221 ataccactgg ctgcaagctt gccatccact tcagcctttg cttcaaccac agctatggtg
    35281 ccacgacgtt ttacaaaagt cgctgtcata accaattggt cgcctggtac aacttgcttc
    35341 ttgaacttaa ccttgtccat accagcgtaa aagaccagtt ttcctttatt ttcaggtttt
    35401 gataactcca acacaccagc agtttgcgcc aaggcttcca taatcagaac acctggcata
    35461 actgggtatt gaggaaagtg gccgttaaag aaaggttcgt taatggtcac atttttgata
    35521 gcaacaatgg tatcctcgct cacttccaag acacggtcca ctagaagcat aggataacgg
    35581 tggggaagag cttctttgat tccttgaata tcgatcattt gatacgtacc aatcctttac
    35641 caaactcaac catttcttcg ttagagacga gaatttccgt taccacacca tccttaggag
    35701 ctgggatttc attcatgact ttcatggctt cgataattac caatgtttga ccttttttga
    35761 cactatcacc aactgtaacg aaggcaggtt tatctggtcc agcagccaag taaaccactc
    35821 caacaagtgg actctctaca agatttccct cactagccac acttgcttca gctggagctg
    35881 gaacttcttc tgctacagtc tctgctggag cagatgtagg agctactgga ttcggtgttg
    35941 ctagaacggg tgctggagcg acttgagttg caacttcagg cacaggtctc gcttcattct
    36001 tgctaaactg caactcatcc gtcccatttt tataagaaaa ttctctcaaa cttgactggt
    36061 caaattgagt catcaagtct ttaatatcgt ttaaattcat acttatctat tctcccaacg
    36121 tttgaaagca agaactgcat tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg
    36181 aatttctttc tccaagcctt gtccataaac gacattagct tcgatataat ctgatacttc
    36241 acttgtccca gctgtcattg gtacaaagtt atgacgcata gcttcgatgg tgacgatagc
    36301 ttctactgca cccgcagccc ccagcaaatg tcctgtaaaa gacttggttg atgatacagg
    36361 tacttcctta ccaagaacag ctacgatagc accactttct cctttttcat tggcaggagt
    36421 tgacgttccg tgagcattga cataggctac ttgctctgga gaaatctcag cttcttccaa
    36481 ggctagtttg atggccttga tagctccctg accttctgga tgtggagaag tcatgtggta
    36541 ggcatcacaa gtatttccgt aaccaaccac ttcagccagg atagtagctc cacgtttttc
    36601 agcgtgttca agactttcta gaaccaacat ccctgaacct tcacccataa caaacccatt
    36661 gcgatcctta tcaaatggga tcgaagcacg agttggatcc tctgtagtag agagagctgt
    36721 taaggcttgg aaaccagcga tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa
    36781 catcacatct tggaaaccaa acttaatgga gcggaaggca tccccaatcg catcatttga
    36841 tgaagagcag gcagtattga tagatttaca aacaccgttt gcaccaaaac gcatggctac
    36901 attcccagaa gccatatttg gtaaagcttt tggaagagtc attggtttga cacgtttggg
    36961 tcctttttca tgaaggcgaa gtacctgatc ttcaatttcc ttgattccac caataccaga
    37021 tgcaacgata acaccaaaac gatccctatt aagagcctct acatcaagat tggcatgatt
    37081 tacagcctct tgggctgcat acaaggcata taaagaatag ttatcaaaac ggttggtatc
    37141 tttttttaca aagtatttat cgaacggaaa atcttggatt tctgccgcat tatgcacatc
    37201 aaagtcacta tgatcaaatt ttgtaatgcc accaatgccg attttcccag ttgctaaact
    37261 attccaaaat tcttctggtg tatttccgat tggagatgtt actccataac ctgttaccac
    37321 tactcgattt agtttcattc ttttcacctc tagctttcgc tacatactta agccaccatc
    37381 aatggcaacc acttgaccag ttagataatc ttggcctgct aaaaatactg tcaaatctgc
    37441 aacctgctct gcctgcccaa attctttcat cggaatctga gctagtgtag cttccttaat
    37501 cttatctgat aagatagctg tcatatcaga ctcaatcatt cctggagcaa tcacattgac
    37561 tcgtatattc cgactagcga cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc
    37621 cttagaagca gcatagttag cttgaccaat attccccatc aaaccaacaa cactagacat
    37681 attaatgata gcaccttctc tggctttcat catcggtttc aagactgatt gtgtcatatt
    37741 aaaggcacca gtcagattga ccttgagcac tttttcaaaa tctgcttctg tcatcttgag
    37801 cataagagta tcttgggtaa tccctgcatt gttgaccaaa acatctactg aacccagttc
    37861 tgcaatagct tgatcaatca tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat
    37921 gggaaccacc ttgataccat agtttgaaaa ctcagcgagc aattcttctg agattgcccc
    37981 acgactgttt aagacaatgt tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc
    38041 aattccacga ctcgaacctg taataaagat atttttatgt tctagtttca tttttttcct
    38101 ttcaaaactt ctacttattt tagtctattt ttctaaaagt gctactaaac tcgcttgatc
    38161 ttccacatga gctaagtgag cagtttgatc aattttttta acaaaacctg acaagacttt
    38221 ccccggtcca atctcgataa agttgcttat gcctgcttct tgcatgaccc caatactttc
    38281 atagaaacga acgggttcct tgacctgacg cgtcaagagc tgagcaatgt cctctttttg
    38341 catcacagca gcttctgtat tgccgactag gggacaagta aaatctgaaa aacttacctg
    38401 agctagagtt tcagctagtt tctggctagc aggctcaagg agagcggtgt gaaagggacc
    38461 tgacacctta agaggaatca agcgtttggc acctgcttct tgcaaaagtt caaccgctcg
    38521 atcaactgca accacttctc cagcaatgac gatttgtgca ggtgtgttat agttggctgg
    38581 agtaaccact ccaagttcag aagctttttg acaggcttct tcaatgacct ctactggcgt
    38641 attgagaact gctaccatct tgccagagtc agcaggagcc gcttcttcca tataggctcc
    38701 acgcttagct accaaggcaa ccgcatcttc aaaatccaag gcgccgcttg ccaccaaggc
    38761 agagtattct ccaagagaca aaccagcaac catatcaggc tgatagccct tttcttgcaa
    38821 taaacggtag atagcaaccg aagtcgctag aatggctggt tgcgtatagc gggtctgatt
    38881 gagtttgtct tcttccgtat cgatgagata acgtaaatca taaccgagca cctgactcgc
    38941 tcgatcaatc gtttctttga caatcggata ctgatcatag aaatcccgtc ccatccctag
    39001 atactgggca ccttgaccag caaataaaaa ggctgtttta gtcatttctt acaactcctg
    39061 cccagcgaga ggcttcttct tgaattttct tagcggctcc gtaatacaaa tcttttagga
    39121 tttcttcagc tgtttcttct ttagaaacaa gccctgcgat ttgacctgcc atgacagagc
    39181 caccatccac atcaccgtga acaactgctt tggctagggc acctgctccc atttgttcaa
    39241 agatttctaa atcaggatct tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc
    39301 tagtcaactg atttttaata gcacgaacag catgaccaaa gtgctgagct gaaatcgtag
    39361 tatcaatatc ccttgctttt aaaattttct ccttgtagtt tggatgggca ttcgactctt
    39421 ttgcaactac aaaccgtgtc cccacctgta cagcctctgc acctagcata aagccagccg
    39481 cagcaccttc accatccgca attcctcctg cagcaataac aggaatagat atagctgtgg
    39541 ctacctgtcg caccaaggtc atggttgtta atttaccgat atgcccccca gcttccattc
    39601 cttctgcaat aacagcgtct gcaccgattt tttccatgcg tttagctaaa gcgacactag
    39661 gaacaacagg aataacgatt atcccagctt catggaaacg ttccatatac ttgcttggat
    39721 ttcctgctcc tgttgtgaca actttaacac cttcttcaat aacgagatcc acgatatctt
    39781 ccacaaaggg agataagagc atgatgttga ccccaaaggg tttatcagtc aatgatttga
    39841 ttttatcaat attggccttg acaacttctt tcggggcatt tcccccaccg ataattccta
    39901 atcctccagc cttggaaaca gcccctgcca aatcaccatc agcaacccag gccatccctc
    39961 cttggaaaat aggatagtca atcttcaata attctgtaat acgcgttttc atagtgcctc
    40021 caaccttcct tgcttacgta atagttcgat ttcaccataa tttgacagtc aaactattac
    40081 ctaaacaaga gggagtgggt ttctccctac tccttctact aatattctgc ttattttgct
    40141 tgctcttcaa cgtaagcaac caagtcacca actgttttca agtcattttc tgcttcgatt
    40201 tggatatcaa aagcatcttc gatttctgag attacttgga acaagtccaa tgaatctgcg
    40261 tccaaatcat caaaagttga ttcaagtgtt acttctgatg cgtcttttcc aagttcttca
    40321 acgataattt cttgtacttt ttcaaatact gccatgatag gactccttta aaataaatag
    40381 tttttttata acaatgtgtt caccacatga ttacctaaat tgtaagaatg agcgtgcccc
    40441 aggtcaagcc tccaccgaag cctgatagaa gaacagtctg gctaccatct aaagggatga
    40501 gaccttgttc tacacactct gaaagtaaaa tcgggatact ggctgcactg gtattgccat
    40561 attccatcat attggctgga agtttggctc ggtcaacacc aatttttcta gccatcttat
    40621 ccaaaatacg gtcattggct tgatgaagta gcagataatc caagtctgtc acctctatag
    40681 gagattcatc aatagtctgc ttgatagact tggctacatc tcgaatggca aaatcaaaga
    40741 ctgtgcgtcc atccatcttc aaaaacgaat ctgcactttc ttgatctgaa aatggagaat
    40801 gcaaacctga atgcccataa gttaaacact cgctgcgact tccatcgcta ttgagactct
    40861 cagctaagaa atgctcttgc tcgctagctt ctaacaagac accaccagca ccatctccaa
    40921 acaacacagc tgttgatcga tccgaccaat cgactgcctt agagagggtt tcactaccaa
    40981 tcaccaagcc tttttgaaag cgaccagaag cgataaactt ttcagcagtt gaaagagcaa
    41041 atacaaatcc actgcaagcc gcggttaagt caaaagcaaa ggctttatta gcgccaatat
    41101 tagcttgaac acgagcagct gtagagggca tcatcgaatc tggagtaatg gtagctagga
    41161 tgataaaatc cagttctttt cctgttattc cagcttttgc catcagtttc ttagcaacct
    41221 ctgtagccaa atcactggta gattctgttc ttgaaatatg cctttgtcgt attcccgttc
    41281 gacttgaaat ccactcatca ttggtatcca taatctgagc caagtcgtga tttgtaacca
    41341 cttgctctgg cacataatga gcaacctgac ttatttttgc aaaagccatt atttcaaatc
    41401 ctccaaaaat tggtaaagat tagtcaagcc tttacccatg acagcaattt cttcctcgct
    41461 catgccatca ataatttttt ctaccatggc cttgtggaag cgtttatgca gtctatgaat
    41521 caagcgaccc ttctttgtca aatgcagatg caccacacga cgatcctgtt ctgaccgaac
    41581 tcgctcaatg tagcccttac gctctaaatt gttcaaactt gtcgtaacag ttccaagagt
    41641 taccatcaac tcttttgaca cttgacttgg agtcacatct ggagccttac cgatgacatc
    41701 aatcgtatgc atttctttga tggagatatc cttaaaacga ctacctctca agttcacttc
    41761 ctcaattaca aggacattgt taaatataga tgttaaatat tcattgattc gttggtagtc
    41821 catttttcat atccctcctt cttcaaaaaa cttttacaat caaaacattt gacagaaaga
    41881 attatatcaa aattcaaaga atgatgcaag tattttttat tttcctgtaa atttaggtct
    41941 tcttctctcc gaatgagctc gcactccttc tttgaaatcc tctgtttgag ctaaggattt
    42001 ctgtaggttc agttctaaag tagcgtaacc ctgccagtct ttaaactggc tctcccaaac
    42061 caacttctta atggcagcat aggaattact tgaagcacgt cttaattttt taagaagctg
    42121 ttctctcgtc ttttcaagtt tttcagcttc agaaacgcgg taaaccaacc cccattctag
    42181 ggctttttct gccgttaaag cctctcctgt catagctaat tgagcagcac gcgtcacacc
    42241 gatactgcgg ctcaagagat gaattccccc tgcatctgga gccaaaccaa caccaacaaa
    42301 ggcttggata aacttagcct tatccgtcgc caaacagaaa tctgccgcaa cagccatatt
    42361 cgctgcggca cctgcaacag caccgtcaac ttccattaaa acaggtttgg ctatttgctt
    42421 gattttataa gaaatcgtat tgaccaactc tgcgattttt gtcaatgatg gaatatcatc
    42481 ctcatccact gcccgcttca tctctaccaa atctccccca actgagaaga cctttccatt
    42541 ggcattgatt aagataaaat gcacagctgg attttcttct gccaaagtca gagcttctaa
    42601 aatctcctca cacatgggaa tatgaaaacc atttgcgacc tcaggacggt tcaaggtaag
    42661 gattgccaag tcctcttcaa gctgataaat aatgtgttcc atcagggctc ctttttattt
    42721 tataagcagt ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcc atctgtaacc
    42781 tcaaaacagt attttgagca gtctgcggct agcttcctag tttgctcttt gattttcatt
    42841 gagtgttaaa ttatttcact gtcaaagtat atctttttta ggagcagaaa gcaagaaaaa
    42901 atcgactgaa agtgtctcag ccgataagaa aggctcgctt taggctagaa agcatcttat
    42961 tttcttcatt gaaaaaagcc tttctttctg ctataatcgt ataaaatact tactttagga
    43021 gttcttatga aagttgttaa atttggaggt agttctcttg cctctgctag tcaattagaa
    43081 aaagttttaa acatcgtcaa aagcgattca gagcgtcgtt ttgtagtcgt ttctgcgcct
    43141 ggtaaacgca atgctgaaga tactaaggtt acggatgccc tgattaaata ctaccgcgac
    43201 tatgttgcgg gtaacgatat tagcaagagc caaagctgga ttatcgaccg ctatgctgct
    43261 atggttagtg aattgggact aaaaccagct gtgctagaaa aaatttctaa aagcattcac
    43321 gccttggcca ctcttcctat tgaagaaaat gaatttctct acgatacttt cctagcagcc
    43381 ggtgaaaata acaatgccaa attgattgct gcctacttta accaaaatgg tatcgatgca
    43441 cgctatatgc accctagaga agctgggatt gtggtcacaa gtgaacctgg tcacgctcgc
    43501 atcattccat caagttatga caagattgaa gaattgacaa acaccaatga agtccttgtc
    43561 attcctggtt tctttggtgt cactaaggaa aatcaaatct gtactttctc acgtggaggt
    43621 tctgatatta caggttctat cattgctgct ggtgtcaaag ctgacctcta tgaaaacttt
    43681 acggacgttg atggtatctt tgcagcccac cctggtatta tccaccaacc acactcgatt
    43741 cctgagttga cctaccgtga aatgcgcgag ttggcctatg caggcttctc agtccttcat
    43801 gacgaggctc ttcttcctgc ctaccgtgga aaaattcctc tggttatcaa gaataccaac
    43861 aaccctgacc atccaggtac tcgtatcgtt ctaaaacaca gtaatgatga atttccagtt
    43921 gtgggaattg ctggtgactc aggctttgtc agcattaaca tgtcgaaata cctcatgaac
    43981 cgtgaggttg gatttggccg caaggttctg caaatcctgg aagaacttaa catcggttgg
    44041 gaacatatgc caacaggtat cgacgatctt tctatcattc tccgttctcg ccaactaact
    44101 cccatcaagg aagaagaaat cctgcgtcag ttggttcaaa aggctaaagt agatcatgca
    44161 gaaatcgaac acgacctttc tatcattatg attgttggtg aaaaaatgaa gagccacatc
    44221 ggagtgactg ctactgcgac acgcgctcta tctgaaaaca aaatcaacat ccagatgatg
    44281 tctcaaggtt ctagtgaagt ttctattatg tttgttgtca ataaagacca agagaaagca
    44341 gcaattaaag ccctctacaa tgcctttttt ggagaaagta aggaagacta agcatggccc
    44401 aatcacttaa caaaacagta ctcctcagta cgacaggcac ttcctacctc tctatcgctg
    44461 ggaaagttgg gaaattcctt gtcggagatc aggctttgga attttaccca gatgtcaatg
    44521 tcgaacaatt tatccagatt ccttggagcc atatcaatca gattggagcc aatgtcactg
    44581 gatgcaaaat cagccgccac ttcgaagtct ttacagacaa aggaaaattc ctctttgctt
    44641 caaaagactc aggtgccatt ctcaaaattg cacgcgacaa attgggcaat gacaaggtcg
    44701 tcaaacttcc gaccctgatt cagacaatta gccaaaaatt taaaaatcta tttgcaaaaa
    44761 aatagaaact ttagtataat catagcaacg gataagtagg ttatcttctt ctttcagaaa
    44821 gtctgcgggt gctgcgagca gataggaggg ataggtgaaa ttctaccgtt agtaacaatt
    44881 acatacacaa tcaagtgcac acctgtgaag ttggatggaa ccgtggccct gccactccaa
    44941 cgttttgtca ggtgtgcttt tttcataaag gagttcttat gttagatatc aaacgtattc
    45001 gtacagattt tgaagctgtc gcagaaaaat tagctacacg tggtgtagat gctgctgtct
    45061 tgaatgaaat gaaagaaatc gatgctaaac gtcgtaacat cttggtcaag gttgaaactc
    45121 tcaaagcaga acgtaacaca gtttctgctg agattgccca agctaagcgc aacaaggaaa
    45181 atacagatga caagattgct gccatgcaaa atctatctgc tgaggttaaa gccttggatg
    45241 ctgaattggc agaaatcgat gctaaattga cagaatttac aacgactctt ccaaatatcc
    45301 cagctgacag cgttcctgtt ggggctgacg aagacgacaa tgtggaagtt cgccgttggg
    45361 gtactccacg cgagtttgac ttcgaaccta aagctcactg ggatctcggt gaagaccttg
    45421 gtatccttga ctgggaacgc ggtggtaagg taacaggcgc tcgcttcctc ttctataaag
    45481 gcctcggtgc tcgtttggaa cgtgctatct acaactttat gttggatgaa catggaaaag
    45541 aaggctatac tgaagtcatc acaccttaca tagtcaacca tgattctatg tttggtactg
    45601 gtcagtatcc aaaatttaag gaagatactt ttgaactcag cgataccaac tttgtcttga
    45661 ttccaactgc tgaagttcct ctggcaaact actaccgtga tgaaatctta gacggcaaag
    45721 atcttccaat ctacttcact gctatgagtc cgtcattccg ttctgaggct ggttctgccg
    45781 gtcgtgatac gcgtggcttg atccgtttgc accaattcca caaggttgaa atggtcaaat
    45841 ttgccaaacc agaagaatct tacgaagaat tggaaaaaat gacagccaac gctgaaaaca
    45901 ttcttcaaaa actcaacctt ccataccgtg tcgttgctct ctctactgga gatatgggct
    45961 tctcagctgc gaagacttac gacttggaag tgtggattcc agcacaaaac aattaccgtg
    46021 aaatctcaag ctgttcaaac acagaagatt tccaagcccg tcgtgcccaa atccgttacc
    46081 gtgatgaagc agatggcaag gtgaaactcc ttcatacctt gaacggttct ggacttgcag
    46141 ttggacgtac agtggctgca attcttgaaa attaccaaaa tgaagatggt tctgtgacca
    46201 tcccagaagc acttcgtcca tacatgggtg gagctgaagt catcaaacca taaaaaataa
    46261 ggtttagcta tttctagcta gacctttttt cgtaaccaaa tcagataagc acctagtaca
    46321 aagaataaaa tagttaggca tataatggtt tcagccaata ccaggtaatc cagaaatgga
    46381 agtttcaaaa ttccctgagc catcttgagc gaggtcgctg tgataatggt tgggaaggtg
    46441 agggctgaga aggctggttg aaaaccttgt tttaaaatgt tgggcagacg agttaaaaca
    46501 aagaaaaaga aggattgaga agccaaaatc atgacaatca agacccaatt cggcaggctg
    46561 gttcctccta ctcgaactag agaagccaag agtagagaga aaggagcaca gtagattcct
    46621 tcttgtccaa gcaaggctag tgggagtgga tgtttcttta aatcgctata aataagggga
    46681 tagagataga aggtcaagag aaaaccaaaa ctcaaggtcg cataggcaat ttcgataata
    46741 cctaccagag gataggtcaa ggcagccact gctatcccca catagagaac cgtccaactt
    46801 ggagtggcat gaaccctccg ccctgaacaa gcaaacttga tggtaaaacc agcaatcaag
    46861 gtcaaatcca agagaaatga aaaccaccaa atcccttgtg ctaccaaagg aagataagag
    46921 aatacgcgaa agacataggt cgataaaatc atcccagcca taggaaaggt tgccattcct
    46981 gacaaaagag ggggcttggt caattcttgc ttggtttctt tccaattaaa gagatgcaga
    47041 attagaaagt aaatccataa aaccaaacca gtcagactaa aaagatggga tagaaccggc
    47101 aacgtatcta aaataagatt tccagctcct gccaaaccta gcaaacaacc tgaaaatact
    47161 aaggggagtt ttttcatcct aacctccaat aatcatgtta gtttcagtat aacataaaag
    47221 cgcttaaatg atgatttaaa aaaacgaagt ccgattattt cagacttcat tttactcaga
    47281 tatgaattag gcataaggtt gcaattctgg attaattggt gtattagcta agttgttggc
    47341 atagttacag aggattgcta ggctgacacc aaaaaccaca tccaaggcat tttgttgagt
    47401 gtagccagct tctaaaaact cagacaaggc ttcatctcct acacgaccct tggtattgat
    47461 aactgccaag gtaaacttag ctagggtatc caatttagga tctgtttcaa ttggagtacg
    47521 attgcgaaga gcttgaatca agtcatcatt catctggatt tgtttgatgg aaaaggctgt
    47581 gtgacctgcg acacagaagg cacaaccatt ggtcacggct gccgtgattt gcaccacttc
    47641 acgctcaacg ggtgtcaggc tgttgcgacg gtggatagat gagacaattt ggtaggcttc
    47701 taaaacagtc ggggcattgg ccaagagacc gattaggttg ggaatatagc cattgttgtc
    47761 tttttctact gtttcaagaa tttctttcac ttctgctggt gctgactcta ctgtatggat
    47821 agtaaatgtt gtcataagat acctcttttc ttattattga cactaatatt attggaaaat
    47881 cttataaaat cctgattcct aagtttatct aagataaagc tttattctct cataagattt
    47941 tcgttgttat attagtttat cacacttcca atcacttgca taatatatat tatatatcag
    48001 gctgataaaa attatttata ggcaaaaaaa tcacacgagc tgtgtgattc cattatttgt
    48061 caaaatactt tttagtttca gcaataacga cttgcgacaa gaccaagagg gcaatcaagt
    48121 ttggcagagc catcaaggcg ttaacgatat ctgcgataat ccagaccata tccaactcga
    48181 taaatcctcc taacaagacc atgagcacaa aaaccacacg gtagagccag ataaagcgaa
    48241 ccccaaagag gaactcaaaa cagcgttctc cgtaatagtt ccaacctaga atcgttgtaa
    48301 aggcaaaaag tacaaggaag atggtcaaga gggcaggccc aaagtgtgaa aagactgttg
    48361 agaaagctga ctgagtcaag gcaaccccat tcaagtcacc actccaaact ccagttacca
    48421 agatggtcaa accagttaga gtacaaatga tgagggtatc aataaaggtt cctgtcatgg
    48481 aaatcaaacc ttgctctact ggttcatttg tcttggcagc tgcagctgca ataggagcag
    48541 aacccagacc agattcgttt gagaacacac cacgcgccac accattttga atagccatcc
    48601 gaacgctagc accagcaaat ccacctaccg cagcaagggg actaaaagct gaggtaaaga
    48661 ctaaagcgat tgtgccaggg atttttccga tattaaagaa aataactata agagttccta
    48721 agatataaat gatggtcata aaaggaacaa cagtagttga aaccttagaa atagacttga
    48781 gtccaccaaa gactgcaatc gctacaaaga cagacaagac gagagctgtg atgactggcg
    48841 aaatcgtcgt tgtattttgg atagattctg taatcgagtt gacttgggtg aaggttccga
    48901 ttcccaagag agcaaccaat actcctgcta ctgcaaacaa aacagcaagt ggtcgccact
    48961 tttctcccat ccctagaagg atatagtgca tgggacctcc cgctactgca ccatggtcgt
    49021 ccttggtgcg gtatttgatg gccaagagtc cttccgcata cttggtagcc attccaaaga
    49081 aagccgccat ccacatccaa aatagagctc ctggtccacc aaccttgata gccgtcgcaa
    49141 ctcctatgat atttcctgtt ccaacagttg atgccaaggc tgtacacaga gctgcaaaac
    49201 tggatacatc accatgtccc ttatcctgga taaaaataag ctgaaaggcc ttgggcagac
    49261 gcaaaacctg caagagtcct agccgcatgg ttaggtaaat ccctgttccg accaataaaa
    49321 tcaagagggg cggtccccaa gcaaaatcat cgattgattt aagcaattct aacatttcct
    49381 tctcctatcg tttcaacccc aaaagaaaga gcacatgcaa gatacatgta ctctggaatg
    49441 cttagataaa tgctaaaaag cggtctatcc tagctctgtc cttttacctg agagtttgag
    49501 cagttgcctg ccttgcccct tcggtgcctt tacggtctct ccagagttcc gtccatttac
    49561 agtcatggaa aatcaaacga ttccccactt ctattaaact tcattcggtg ttggtattta
    49621 attgattcta attttacaaa aaatgttggc ttttgtcaat gtgtttatta gtaaaaatta
    49681 gttcaacagt ttttacttta taaagtccag aatactgcta tcctttaaaa gtgacaatag
    49741 tcgcaccact gcctccagca ttttgtgggg catagccgaa actcttgaca tgtttgtttc
    49801 tttgcaagta tttggtaact ccttcacgga tgactcctgt tccgatacca tggatgatat
    49861 caacttgagc catattgtta agcaaggctt ggtcgatgaa ggtatctagc tcattcatgg
    49921 cttcttcata gcgcttgcct cgaagatcca gtctagcttg aggtcctcgc ccagaagttc
    49981 gtttcacaac attgacctgt ttcttcttga ctggtttttc ttgctgggct tgaacaagat
    50041 caaactcttt ctcttccaag gtcatcttaa tcaagccaac ttgggcttcc cagcggccgt
    50101 ccttgagttg actggtcaag gtaccacgct gaccataact gagaaccacg atatcatctc
    50161 ccacctttgg agctcgtttt ttcttggcct tttgaaggac cttgttttta gacaagtcca
    50221 ctttttcagg agccaatttt ttcaacttgg ccttggcttc aatgatttcg tggggcttga
    50281 gttgggattt actgtggaga tttttgagaa tctggtcact ttcacttagg gccatatcca
    50341 caatctcagc agcctgttca cgcgccttgt taagctcggt ttccttttca cgattaagct
    50401 cgttgtagag tttttttagc gcacggttca tcttgagatt ttcttgctcc acctcacgga
    50461 tattgtccaa acgtttgcgg ctttccagcg tctgctcttc taattgctca atgatacgat
    50521 tgacgtcatt gtcctgatcg atctgctgac tggcatctcc tacgataact tcagataggc
    50581 ctagacgttt ggcaatttca aaggcattac ttcggccagg aacaccctgc ataaagcgat
    50641 aggtcgggcg aagagttgca gtatcaaact ccatactggc attttgcaca aaggctgtct
    50701 caataccgta ggccttgagt tctggatagt gggtcgtcgc catggtcttg atttgacgca
    50761 ggcgaaggtc ctccagaata gccatggcaa gggctgctcc ctcttgggga tcagtaccag
    50821 cccccaactc atccaaaagt aagagtgaat gttggttgac cttgccaaga atatccacga
    50881 tattggtcat atggctagag aaggtagaca agctctgctc aatagactgc tcatctccaa
    50941 tatcagcaaa gatttcttca aaaataccaa cacgacttcc cttgtctgct aaaatcggca
    51001 atcctgactg ggccatgacc tgtgtcaagc ccagagtttt gagcatgatg gtcttcccac
    51061 ctgtattggg acctgtaatg acaatagctg ttaaatcttg accaaaatag acatcatttg
    51121 cgacggcatt tttgaccaaa ggatggcaga catggagcag ttgaatctct tgattttctg
    51181 acagctgagg cacgactgct tgtctttctt ggataaatcg aaccttggca cgaatcaagt
    51241 ccagatgacc gataatccaa gcgtcattag caatctcagc cgcatgaggg cggacacgct
    51301 cagaaatttc ttggagaatg cgaagcattt catagcgctc atctgctcgc agactagcaa
    51361 tttcttcgct cagtttgact acctcacgtg gttcgatata gacggtgttt ccactagcag
    51421 aaatatcatg aacgacacct gcaatcttat tgcggtaggt gtttttgact ggtaaaacct
    51481 gacggccatt tctgctagca acaattcctt ccgtcaacat ctgcgctttt tgcttgagta
    51541 agtcttgtaa aacatcgcgc acctgactct cgctatcatg tatttttcga cggattcgcg
    51601 ccaattcttc actggcaaaa ttttcaatga aacccgcatc attaaaggcc tgaagatttc
    51661 cttgtaattg cggaaaatca tgtaatttct caaaccaaag ggctaattct tccaagctga
    51721 cattttccag attggcgtaa aaattttgaa gttctcggct ggcaagaagc acgcgtttca
    51781 agagtaggaa ctcctcgata ttgagatccg ctcccatctc caacctcttg cagactcctg
    51841 caatttcctt agttgagaga atagtaaaat gcggttgctc gacgaaaaga gcctgcattt
    51901 ctttcatctc agcaaaagcc tgtttgattt tatctgcttt ggcagtcgga gccagctgtc
    51961 tcaattgctc caagccctgc tcggtcaaca aatgaggctc aaacaaggcc ttgaccttat
    52021 cgaactctaa tgtttctaat attttcttat tcatctttat ttccttgtct ttgaatgtct
    52081 aggtgtggta gctttttaca ttctgataga ttcgagtcaa atctgtaaac aaagggctag
    52141 gaaaactcct gcccttttta tccgattaaa tttgtcaccc agatttgttt gagccaactg
    52201 gttgttaccg gtatgctctg gatgatgtgt tttgcgacga tactcttttc aagaggattt
    52261 tgtataactg ccatggggat ggtcgccaag attgtcaagg ccatttgcaa gacaaataag
    52321 gtcaccaaca tggacaagat acctgctgaa acttggaaca acttaccacc cagttttttg
    52381 ctaggaatca agtgtaagag aagaccaagt aaacgaccaa tgctatagac aatcccaaat
    52441 acaagcaagt agccgatacc tgcataaaag accttatcca gctgaaagag ttgatccgat
    52501 gggaaaaaga aagtcccctg accttcctgc gaatttgcat aagggagcaa taaatggaat
    52561 tgctctccaa gccccttata aaactggcca gccataaaag ccgatgccat ggctgaaatc
    52621 aggtaataaa cctgtaagag caggcctctc cgatagccga tataaaatcc ccaaaccaag
    52681 accaatagaa gaaggaatga aatcataagg aatcctcaat cttgctctgt tcttgcttac
    52741 aagtcacaag cttgtgacgg agttcttcta gctcttgctc cttatcgtca aattcaatct
    52801 cacggctgag ctgagttgat aaacagttga ctgccaacaa aagagcgatt gtttcatcat
    52861 ctgcgctagg catttgttct ttaattgctt ggtatttttc tgtcgcaacc ttagcgattt
    52921 cctccataaa aaggttgtca tgttcgcttg tcaaggttaa cgattttttc ccgaatgtaa
    52981 atttgaatcg atttagattt gccataaaat tcacctcacg atattatacc aaaattcgct
    53041 aattttgtca gtttttacaa attttactgc ttttgtggta caatagaaac tatggcaagt
    53101 atcacactca caccaagcga aaaggatatt caggcttttc ttgaacacta tcaaaccagt
    53161 ctggctccta gcaagaatcc ctatatccgc tactttttga aactacctca agcaacggtt
    53221 tctatctata cttctggaaa aatcttgctt cagggtgaag gggctgaaaa atacgccagt
    53281 ttctttggct atcaagctgt agagcaaacc agcggacaaa atcttccttt aattgggaca
    53341 gatgaggtgg gaaatggttc ctactttggt gggcttgcag ttgtggctgc ctttgtcaca
    53401 cctgaccagc acgacttttt acgaaaactc ggtgtggggg attctaagac tctgaccgac
    53461 caaaagatcc gtcagattgc tcctattctc aaggaaaaaa ttcagcacca ggcactcctt
    53521 ctctcaccca gcaagtacaa cgaggtcatc ggagaccgct acaacgctgt ttcggttaag
    53581 gttgccctcc ataatcaggc tatctatctc ctccttcaaa aaggtgttca gcctgagaaa
    53641 attgtgattg atgcctttac cagtgctaaa aattatgaca agtacttggc acaagaggcc
    53701 aatcgtttca gcaattctat cagcttagaa gaaaaggctg agggcaaata cttggctgtc
    53761 gcagtttctt ctgtcattgc gcgtgatctc tttctggaaa atcttgaaaa tttgggacga
    53821 gaactgggtt atcagcttcc aagtggagct ggaacggctt ctgacaaggt ggctagccag
    53881 attttgcaag cctatggtat gcagggactc aacttctgcg ctaagctaca ctttaaaaat
    53941 actgaaaaag cgaaaaacgc ttagaaaggt aagttatgaa tttatttaaa aatttcttaa
    54001 aagagtgggg attattcctc ctgattctgt cattactagc tttgagccgt atcttttttt
    54061 ggagcaatgt tcgcgtagaa ggacattcca tggatccgac cctagcggat ggtgaaattc
    54121 tcttcgttgt aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag
    54181 atgggaataa ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg
    54241 aaaatgataa actctacatc aatgacaaag aaacggacga gccttatcta gcagactata
    54301 tcaaacgctt caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa
    54361 ataaaggaac tttctttaga agtatcgctc aaaaagctca agccttcaca gttgatgtca
    54421 actacaacac caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg
    54481 accgcttggt ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag
    54541 gggaagctaa attccgctta tggccaatca cccgtatcgg aacattttaa gaaacctaag
    54601 aggccgagaa tcaccaatct cagcctcttc ttctatcgtg agaaaatgat tggtaactat
    54661 ctaaacttac cagaacagaa acacctcaac tctcacctat tcatgcaaag gaattttatg
    54721 gaagtttatt tttcaggaac cattgaacgg attatttttg aaaatcccag caatttttat
    54781 cgcatcctcc tcctagaaat cgacgatacg gacgcagagg attttgatga ttttgaaatc
    54841 attgtcacag gaaccatggc tgatgtaatt gagggcgaag actatacttt ttgggggcaa
    54901 attgtccagc actccaagta tggagaacaa ctgcaaatca gtcgttatga tcgcgcaaaa
    54961 ccaactagta agggcttggt caagtacttt tcaagtagcc atttcaaggg gattggtctc
    55021 aagacagctc agaaaatcgt ggatacctat ggcgaaaata ccattgacga aattttgcaa
    55081 cacccagaaa agttagaagg catcgcagga ttctctgcca aaaatcgcga ggctttcgtc
    55141 tccactctcc gtctcaacta cggaacggag atggttttgt ccaaactagc caactacggc
    55201 attcccaaca aactagcctt tcagattcaa gacttttaca aggaagaaac ccttgatgtg
    55261 gttgaaaatt atccctacca gctggttgag gatatcaagg gtttgggctt tacaattgct
    55321 gaccaactag ctgaggaact aggcatcgaa agtcaggctc ctgaacgctt ccgcgccggt
    55381 ctagttcaca gtctttttca ggcctgtatg gaaacagggg acacctatgt tgaagcacgg
    55441 gatttgctgg aacaaaccct tactctcctt gagtcttccc gtcccgtgga actagacccc
    55501 agccaagttg cccaagagct ctcctacctg atcgaagaag acaaggttca gcagattgat
    55561 accaagatct ttgacaacag cctctttttc gctgaggaag gtatccgcag tcacttgatt
    55621 cgtatccttg aaaaaggaaa acagaagagc caagatttag aaactattca aaagcatatc
    55681 actactgtcg agcaagagct gggaattgag tatgataaca ttcaaaaaca ggctatctgt
    55741 gatgctatcc agaataaggt ctttatcctg acaggtggac ctggtactgg taagacaact
    55801 gttatcaatg ggatcatcgc tgtttacgcc ctgttagagg gacttgacct caggaagaaa
    55861 agcaatctgc ccattcttct tgctgctcca actggacgag ccgctcgccg catgaatgaa
    55921 ttgacaggtt tgcctagcgc gaccatacac cgccacttgg gaatgacagg tgacgatgat
    55981 accagtcatc tggaagatta cctagatgct gactttatca tcgtggatga attctctatg
    56041 gtagatactt ggctggccaa tcaactcttc tccaatatct cttctaacag taagatcctc
    56101 atcgtaggtg acagtgatca gctaccttct gtcagtcctg gacaggttct agcggatctg
    56161 cttcatattc ctttgattcc tcagactcgc ttggaaaaaa tttatcgaca aagcaaagaa
    56221 tcaaccatcg tcaccctagc tagtcagatt cgacagggca tcttgccagc tgatttcacc
    56281 caaaaaaaag ctgaccgttc ctactttgaa attgctagtg gccatattcc tgccaccatt
    56341 gaaaaaatct taggtgtcgc cctcagaaat ggtattcctg cccgtgatat ccaagttctg
    56401 gctcctatgt accgagggac ggcagggatt gatgctatca atcagctcat gcaagacctg
    56461 ctcaatcccc cacaaaaaga tcaactcagt tttgaagctc ctcagtgcca ctatcgtaag
    56521 agagacaagg tcattcattt ggttaacgat gctgaaatca atgtctttaa tggggattta
    56581 ggagctatca cagacctgat tcctggtaaa tacaccgaat cgaaacaaga cgagattgtc
    56641 attgattttg atggtaatga agtctcttac ccccgtaacg aatggtacaa gattcgcttg
    56701 gcctatgcca tgagtattca taagtctcag ggaagtgagt tcccagttgt catcctaccg
    56761 attactagtg ctagccgacg tatgctggag cgaaatctca tctacacagc cattacacgt
    56821 gccaaaagca aactcatctt actaggcgaa ttacaagcct tcgactatgc tacccaacac
    56881 atcggaactg cccgaaaaac ctatctgatt gaacgcttca gtgatctact ggagaatgtt
    56941 gaagaaaagc aacaagctgt ctctgaaaca gtcacatcaa gtgcctctga acaatcctac
    57001 atcctaaccg aagaaaactg ggaccgcatc ccagccatga ttgggattac agacacagac
    57061 ctcaaagaga tttttggaaa atagtgcatc agaaaaccca ccaattcagg tgggttttct
    57121 gtttattaag attattttac tgttgctgtg cttgtgatca attcaacagc ttttttgata
    57181 gtgatatcat gtttcaacat gtcagctgaa agcaagtttt gaacttgtgc aacttccatg
    57241 ttgtagtctg ctgccaattg ctcaacttct ttttggattt cttcttctga agcatcaaat
    57301 ccttcagctt tggcaactgc ttcgataaca aggttagtct tagtacgtga ctcagcttct
    57361 gcttggtatt ggttgtgaag gtcttcttga gtagttccag tgatttggaa gtacatgtca
    57421 gggttgatcc cttgacgttg caaattccca aggaattcat ttactgaacg gtgaacttct
    57481 tcatggatca tttcttctgg aagttctacg atttcagcat tttctacagc tgtatcaatt
    57541 gctgcacctt caactgcatc tttgtaagct tcttctttag cagcagccaa ttctttgcgg
    57601 tatttttctt tcaagtcagc aagtgtttca acttcttcat caatgtcttt tgcaagttca
    57661 tcgtcaagag ctggaacttc tttagctttt acttcgtgga tagttgtcac gaatttagct
    57721 tctttacctg caaggtcttc tgcttggtag tcttctggga atgttacgat aacatcaacg
    57781 gtttcgccag ctgagtgacc taccaattgg tcttcgaaac cagggatgaa ttgacctgaa
    57841 ccaagtccaa gtgagaagtt ttcacctttt ccgccgtcaa attcaacacc gtcgatagaa
    57901 ccaacgaagt cgatcacaac agtgtcgccg ttttcagcag cagcttcctt gataaccaat
    57961 tcagccaggt tgttgcgttc gcgttcgata cgctcttcaa catcagcgtc agttacttct
    58021 ttttctacat caactgatac ttcaaggttt ttgtagtcac ccaattttac ttcaggtttt
    58081 gtaacgactt cagcagcgat aacccagtct tgaccttttt ccattgaagt tacgtcaatt
    58141 tttggttggg caaccacttc aagaccagct tcttttacag ctgcttcata agcgtttggc
    58201 aaaagagcgt tcataacgtc ttggtaaagt gattcttcac caaatttttt atcgaagata
    58261 ggacgtggaa ggtgaccttt acggaaacct ggaacattaa gagatttctt cactgacttg
    58321 aagacacggt ccaattctgg tttgatttgg tcttgagaga tagtgaaagt caagacacca
    58381 cggtttgttt ctttgttttc aaatgataca gacattctgt catttctcct taaaattttt
    58441 taaatacagt ctattataac attttctata aataaaatct agactaatgc agccaattat
    58501 agacaacaag cctttttcct aactaaaaca ctcataaagt atagacaatt ttagactact
    58561 ttggatatct tttggttagt cattttccaa aactaattta tctaattttt cagttatatt
    58621 tgacttcatc ttctcagtaa catgagtata aacacttaaa atctttgttt cattagtata
    58681 atctacacga tccattatcg ctgttatagg tacttccaat tcagcaagca aacttatatg
    58741 cgaatatcta aaaacatgag cagtcaatac aaaatcatct ttcttaattt cacttttcct
    58801 aaaactgttt ttcaaaaagt aattgaaaca agttatcatt aagggagaac cattatttgt
    58861 aaatatataa tcaccttctt ctaaaagaag atattctttt aaaatttcta acactctatc
    58921 actaatacca attactctat atgaagctaa acttttcgga ctatccaaaa atacttcgtt
    58981 attggacgat tacattatag taaaacgaaa taagaacagg acaaatcgat caggacagtc
    59041 aaatcaattt ctaacaatgt tttagaagta gaggtgtact attatagttt caatctacta
    59101 tacaagacga aattgaagaa atctttccat tataaaacgc atattatcaa ggtttttaaa
    59161 cacctaataa tatgcgtttt ttcctatttt aaagactttt atccacctat tatacaaagt
    59221 taagtatcca tcacagttta caattagcct tcattaccta acccattcac catccttcaa
    59281 gagagtaacc tttaagaacc gaataaataa atggcaaatt tcgttcattt aatttaactg
    59341 cactgttaat ttgattagct ccatctccta aagtatgcac tcctactaca cggtgactag
    59401 catcataaac tgtagatcca ctagacccct ctaaagtatc aacttggtaa tccaagaaca
    59461 tgccatcatc acttaaaact tgttttttat ctgtatacat ttgatgaatt ttaaaattat
    59521 atgatagata gcctgtgata gtcacagtta ttcctgtcaa atttttttga ctagtaggaa
    59581 gacccaaagt ccctaatttt gcaccaatgg gctcttctag aattaataaa gccaagtcat
    59641 attcccttgc atccttagaa tttaaatttc taaattcctt caaataacga acttccttta
    59701 ctttgatctt tccaaatagt tcttgacttg gactaacagc cggaagaaca taaatatcat
    59761 ccgcttcttt cccatagtca tgtctgtagt agttgtgagc cgctgtaatt aacacattat
    59821 ctttaataaa attcgcactt cccctccctt ctacattcat tccatcggct actccataat
    59881 acttagataa aaccatagct gaagtcgaat acggatactg taaagtatta tcaattttaa
    59941 tcaaatcatc attaccgata atacttctga ttgcttttgg tagtatgaac catacgttgg
    60001 tgaaatctca gataatgaag aatcattaga ctctggacct ttttctagtg tctcacttac
    60061 ctcatattct tcacctgtac tagaaataac actcaaagca gatactgtcg ataactggct
    60121 agccaataaa gtactcgcaa taattgaaat acccaatttt ttataaacag ttttcttcat
    60181 tattgtatcc tcctaatgta attatagcgt actattctaa atttcttaat ctactataga
    60241 atcaagaaat ctaccacctt ctttaaatac cctccattat cacataaaca ggtaaacttt
    60301 tcaattaatg actgcgcttt tcaatcacgc tagaggtact tgcttgcttc tttgatacta
    60361 agttcagcca ttctttcctt gtttttctca ataaagcatg ttacccaagt gggattcgtt
    60421 ttggagtagt ctcgcagagt ccagccaatg gctttattga taaaaaattc tgtttggttc
    60481 aagttatgaa gtagaatctt ttccattaat tgagtattgg tcttctcttt tcttaacaac
    60541 tggtggtcaa tagcgacacg tctcagccag atattatctg ataggctcca ttttatactc
    60601 aatgaaaatc aaagagcaaa ctaggaagct agccgcagat tgctcaaaac actgttttgg
    60661 ggttgcagat agagctgacg tggtttgaag agattttcga agagtattaa gattatttct
    60721 tctagttcag agtgttcata caccaaactc cctactactc gatctaggat atctaccgtg
    60781 tcccaccagg attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga
    60841 taagactgca ttgctttcaa atagttagca gccacatatt ggtattctct aggatccttt
    60901 tcccagcaag tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggaaaa
    60961 tatttttata gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc
    61021 gcatataggc ttccatggac cttgcttttt tagagtcttt tgctgcttct agctcctcaa
    61081 gtaaatctgc taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat
    61141 agacagccgc ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg
    61201 tcttgaccgt cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct
    61261 tggcgatgag ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat
    61321 gattgcggtg gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag
    61381 ctaccttact gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt
    61441 tggcaccagc atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca
    61501 aaatcttggc ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct
    61561 caggcatgac aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc
    61621 cttgagaccc gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc
    61681 ttttcaagcc caatcggacc atttcatggt catctactag taaaattttc atctttactc
    61741 ctttatcatt ccttatctaa caggggaata cggatatcaa ccgccagccc ttgcttggga
    61801 gctgtcaaga gttgaactgt tccagccata tcttcaaccc gctccttgat atttcgcagt
    61861 ccataactca agtcgtctaa gctccctaac tggaaaccaa tcccattgtc caccaccttc
    61921 agttgcaatt caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg
    61981 cggagggtat tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta
    62041 ggcaatttcg tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct
    62101 tttaagagaa tttgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa
    62161 tgcaagagca aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc
    62221 aactggatct gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa
    62281 atcatgtggg ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc
    62341 ttccgttcct tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga
    62401 agagcttctg tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct
    62461 ggatctgcaa cctgaaccac ttcttgccct gccaataaac gcttgagatt agcctgcatt
    62521 tttcttagag aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggttatggac
    62581 atgctgaaaa ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag
    62641 atagaccagt caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaacagg
    62701 aaggaggtga gagcaataat gacataggct tgttttttca tcctctaacc acctccacat
    62761 caccaatcat agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg
    62821 tttcttgatg atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat
    62881 ccccatagag acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg
    62941 tcgttcctac catctttctg aggataatga cattgtcatg attggttaag atgaccctct
    63001 ccagatgaat agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag
    63061 tctggtagct tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg
    63121 tcacgacctc ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa
    63181 gaagaaagag gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca
    63241 taacgatgaa aaagaagaga atggttgccg ctactaaaag aagattattt ccctctttac
    63301 cagtgtagta gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat
    63361 gctctgatac catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga
    63421 ttttaaattt tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc
    63481 acctcagtct gaggatggaa aaaaggcgct ggttacgcct ttttcatctg atcctttgct
    63541 tcttttaatt ttccataaag aagatagtct actttttgta gatctgctat ggtggcacag
    63601 ttaagggaac acataatcaa gcgtaggtct gctttccagc cttggacaat gccaatcact
    63661 tcttcaactg tgtaggtttc aaccaattcc agaacggttc gtgacaatcc cacagactta
    63721 gcaccaaaaa ccaagcactt aatcatatcc agcggattcc gaacccctcc actaaccaag
    63781 agttcgacct tatctttcca ttcttgggca ttgagaaggg cctgcatggt agactgaccc
    63841 cattgattga ggtaatcacg ctggccacta cgacggtttt cgatataggc aaagctggtg
    63901 ccaccacgac ccgataggtc cactgtacga acaccgaatt cataggctct ttcgattgtc
    63961 ttggcatcca ttccaaagcc cacttccttg aggacaatag gaacgggaat ttgttcgcta
    64021 taatctgcta gatgcgattg ccagcttcta aacttccttt ctccctcggg catgagtaat
    64081 tcctgcatga cattgacatg cacttgcaat agaacaggat tcatctcttc tacagtctga
    64141 agccctaact cgacaggctt gtccaatcca atattggttc caaggaggag attgggatga
    64201 ctagacttga cagaaaaaga atcatccgtt ggatttttga gggctgcgct ataagaaccc
    64261 gttacaaata aaataccaca ggattccgcc acctgagcca gcttttgatt gatttctctt
    64321 cccttattac ttccaccagt catggcattg atataaaaag gaaagtccca ctttcgacca
    64381 gcaaactctg tcgaaagatc gatttcatcc agattgtaaa gaggcaagga agaatgaatc
    64441 agctccacct catcaaagct attataggaa cttttctgct caagggcata gaggatatgc
    64501 tcgtccttac gatttgtcgt catgtcctat cctttcttga tataagagct caatccccag
    64561 atcggcccaa cgatttttta aggtttcggt tgattgcgca tcaaaactca aggcgatgcc
    64621 acagtcacca ccaccagcac cactactctt ggcaacggcc tgcaaatctt gactggcttc
    64681 tttcaactgt ctaagcaaag gcgtgtaaat atctgtactc aagccttcta aaagcttgct
    64741 ggctacttct acttgctcga taactttttc ggctttcccc tgctccaagg cttcgaccaa
    64801 agaaaccacc gtttcttttg aggaacttaa aaaattttga ttgatatttt gcttgatttg
    64861 ctggaccatg tgactcgata cagccacttc cttggtccat cccactaaga aatcacattc
    64921 taaagttggt ttcacttgtg agataaaaaa tccccaatca cgctccagaa ctgtcgccaa
    64981 gttttcttct tctaaccaag cagccacctt ctggcgatca aatgactggt agagaaccaa
    65041 atcctctgcc acaatacagg caaggtcgcc catggaacca ttgtctcctc gcttgagcaa
    65101 gacagcgcta gtcagcttga acaagagatt ctgatcaacc gaaagattat agagagccag
    65161 taaagccttg acaaccaaga caacgacgct gccactagaa cctagaccaa actttttccc
    65221 ttctcgttcc attttgccac agatttttag ggaaaaaggt cttaaattct gaccgcgaac
    65281 agcgaggaag tctcccatca aagcaatcgt ttcttgaatc aagctgtagt caggattagg
    65341 ccttaagtcc actgcgaaat caaacatatc tgaatagata cggtagctgt cagaaaaagc
    65401 aatttcagcc ctcatataga tgggaatatc ctttatcaaa gctaactgcc ctggctctaa
    65461 aatagcatat tcacctgccc aatagagttt tccgcaagtt ttaacagcaa tcatcttgac
    65521 tcaaatcctt tgtttttgac acaatcaagc gataacgctg accgaaaatt tctgataaat
    65581 gctccaagtc tttctcctga cagaagacct taacattggg accagcatcc atggtaaagt
    65641 agcaggcctc tcctttctca cgaagctggc gaacaaagtc catagcctca taagaggcat
    65701 ccgtcagata agaaaaggct ggactagcag tctttgtcgt agcatgcata gccagggcat
    65761 ttttctccgt taattctcca atcttggcaa aatcattttc cttgagataa atcagcatat
    65821 cctgatagtc cttctcagac tgacgaaccc agtcgtcgaa agtcgtcgag gtttccacac
    65881 aaagtttcat cccgtcacgg ctagagattg gttttttctt gtcctctagc accaacataa
    65941 tcatagctag tttcaagtct gtctctacag ggtaaatttc tccactatcc ttatcccagg
    66001 ctcctagtgg tccataaaaa ctccgagaag aagagcctga ggcaaacttg gcttcctgcg
    66061 ctaactgact tctatccaat ccaagcttga aataagcatt acaagccttg accagggcgg
    66121 acaaaccact agaacttgag gacaggcccg ctgccgtagg catattgttt tgagtatcga
    66181 tacggacaaa gccctcacca gctggacgat aacggtcaat aatcttactc atcttggcat
    66241 gctcgacctc attttgtagc tgaccattga tgtaaaattc gtcagctgtt acattggctg
    66301 gtaaaggcga caaggtcgtc tctgtataca tattttccaa agttagagaa atactgctag
    66361 tagcaggcac catctctttt tcttttttct ttccccaata tttgataata gcaatatttg
    66421 cgtaggaacg tactgttaca ggctctctat ccatgtctga acagctcctt tctcttctaa
    66481 tctttctgct agttcttgtg cgtgtgtcaa attggttacc aaggctatga tacaacctcc
    66541 tagcccacca ccgctcatct tggcacccag agcaccatgg ctaagagtcg tttcaaccaa
    66601 aaagtctgcc tcagggctac tgactccaat ttcttttaaa tgtaaatgcg cttgactgag
    66661 gatttgtccc agtccttcag catctttttg tgaaatcgca acttctgctt gctgggttaa
    66721 ttctcccaag gcatgcaaaa acggtagggc atccttgccc ttattttgaa ccacttggat
    66781 ggcttcacga gtatgaccat aaacacccgt atcggcaatc accaaatagg cggataaatc
    66841 catctcaagt tctgtaaatc ctacgttctt gataaagcga ataggttggt cactgagaca
    66901 ggtcttagca tccaaaccac taggattcat atgggcaatc atttcagctc gattgaccaa
    66961 gatttctagt acatcatgag gcagatcagc ctgatagtag tcaaataccg cacgaatggc
    67021 cgctatgctg atagccgctg acgaacccat cccccgtttc tcagggatag ccgagtcaat
    67081 ctcacaacga atgcaggctt ctgtgatatc caaatactcc agtgaggcat aaaccgccat
    67141 ggacaaggta tcctcctcat aaaggcgcca aggactctct gcaggaacta ccttacaggt
    67201 cacctccacc tccaaaagag gcagggaaat ggcaggataa ccgtaaacga ccgcatgttc
    67261 ccctattaaa attatcttac tatgtgcctg accgacacca actttttttg tcattttttc
    67321 cttttactag acgaaaaaac gtcttatttt tcatacaagt attaattctt tcctatctat
    67381 tttattatat tttcacaaaa aaagcgattg tttccattca caatcgcttc tttcattacc
    67441 gaacccattc accattataa ttgacagaat agccatctac aatcgtattc actgccaagg
    67501 cacctgagct ataagcgtag taccatctgc cattgacctg gaaccaacct gtcgtcatag
    67561 aacgatgaaa gaaactccat accattaagt aaagaggaaa gtcatgaggg agcatgcgtc
    67621 attgacaacc tattttagtg acgtacaaag tttcattaac aagtactcgt ttcggccatt
    67681 tataggtgcg gtgtttgcag aaatagggtt caatcttcgc ccattcttga tcgtttaaat
    67741 cagtatcata tgctttgcgt gtcataactc tagtttaaca tttttttgtg aatacaggtt
    67801 ctaaataatc gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg
    67861 aaacttatgc acttaatttg acaactcaat atgtaaaaat atatactata
//
LOCUS       DAVBOU010000004        64454 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBOU010000004 DAVBOU010000000
VERSION     DAVBOU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.004"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ879_000209"
     CDS             complement(1..1959)
                     /gene="ftsH"
                     /locus_tag="VQ879_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3142443.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ879_000210"
     CDS             complement(1975..2517)
                     /gene="hpt"
                     /locus_tag="VQ879_000210"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3142444.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ879_000211"
     CDS             complement(2521..3798)
                     /gene="tilS"
                     /locus_tag="VQ879_000211"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3142445.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3795..5063)
                     /locus_tag="VQ879_000212"
     CDS             complement(3795..5063)
                     /locus_tag="VQ879_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3142446.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5183..5551)
                     /locus_tag="VQ879_000213"
     CDS             complement(5183..5551)
                     /locus_tag="VQ879_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3142447.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5544..5810)
                     /locus_tag="VQ879_000214"
     CDS             complement(5544..5810)
                     /locus_tag="VQ879_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3142448.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ879_000215"
     CDS             complement(5868..9377)
                     /gene="mfd"
                     /locus_tag="VQ879_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3142449.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9378..9947)
                     /locus_tag="VQ879_000216"
     CDS             complement(9378..9947)
                     /locus_tag="VQ879_000216"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3142450.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ879_000217"
     CDS             complement(10018..11133)
                     /gene="ychF"
                     /locus_tag="VQ879_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3142451.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11217..11411)
                     /locus_tag="VQ879_000218"
     CDS             complement(11217..11411)
                     /locus_tag="VQ879_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3142452.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ879_000219"
     CDS             complement(11476..12612)
                     /gene="dnaN"
                     /locus_tag="VQ879_000219"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3142453.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ879_000220"
     CDS             complement(12771..14132)
                     /gene="dnaA"
                     /locus_tag="VQ879_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3142454.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAEVIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14345..15103)
                     /locus_tag="VQ879_000221"
     CDS             complement(14345..15103)
                     /locus_tag="VQ879_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3142455.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15161..16342)
                     /locus_tag="VQ879_000222"
     CDS             complement(15161..16342)
                     /locus_tag="VQ879_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3142456.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ879_000223"
     CDS             16525..17004
                     /gene="rlmH"
                     /locus_tag="VQ879_000223"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3142457.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRITLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17048..17121
                     /locus_tag="VQ879_000224"
     tRNA            17048..17121
                     /locus_tag="VQ879_000224"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17082..17084,aa:Arg,seq:tct)
     gene            17286..17411
                     /gene="comC"
                     /locus_tag="VQ879_000225"
     CDS             17286..17411
                     /gene="comC"
                     /locus_tag="VQ879_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3142458.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17432..18757
                     /locus_tag="VQ879_000226"
     CDS             17432..18757
                     /locus_tag="VQ879_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3142459.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18754..19506
                     /locus_tag="VQ879_000227"
     CDS             18754..19506
                     /locus_tag="VQ879_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3142460.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19558..19629
                     /locus_tag="VQ879_000228"
     tRNA            19558..19629
                     /locus_tag="VQ879_000228"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19591..19593,aa:Glu,seq:ttc)
     gene            19635..19708
                     /locus_tag="VQ879_000229"
     tRNA            19635..19708
                     /locus_tag="VQ879_000229"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19669..19671,aa:Asn,seq:gtt)
     gene            complement(19749..20291)
                     /locus_tag="VQ879_000230"
     CDS             complement(19749..20291)
                     /locus_tag="VQ879_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3142461.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20470..21237
                     /locus_tag="VQ879_000231"
     CDS             20470..21237
                     /locus_tag="VQ879_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3142462.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21241..21660
                     /locus_tag="VQ879_000232"
                     /pseudo
     CDS             21241..21660
                     /locus_tag="VQ879_000232"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21688..22002
                     /locus_tag="VQ879_000233"
     CDS             21688..22002
                     /locus_tag="VQ879_000233"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3142463.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22103..24655)
                     /locus_tag="VQ879_000234"
     CDS             complement(22103..24655)
                     /locus_tag="VQ879_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3142464.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24717..26339)
                     /locus_tag="VQ879_000235"
     CDS             complement(24717..26339)
                     /locus_tag="VQ879_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3142465.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26545..27570
                     /gene="trpS"
                     /locus_tag="VQ879_000236"
     CDS             26545..27570
                     /gene="trpS"
                     /locus_tag="VQ879_000236"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3142466.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27722..29200
                     /gene="guaB"
                     /locus_tag="VQ879_000237"
     CDS             27722..29200
                     /gene="guaB"
                     /locus_tag="VQ879_000237"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3142467.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ879_000238"
     CDS             complement(29251..30348)
                     /gene="recF"
                     /locus_tag="VQ879_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3142468.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ879_000239"
     CDS             complement(30351..30719)
                     /gene="yaaA"
                     /locus_tag="VQ879_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3142469.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30878..32128
                     /locus_tag="VQ879_000240"
     CDS             30878..32128
                     /locus_tag="VQ879_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3142470.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32125..33408
                     /locus_tag="VQ879_000241"
     CDS             32125..33408
                     /locus_tag="VQ879_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3142471.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33450..34271
                     /locus_tag="VQ879_000242"
     CDS             33450..34271
                     /locus_tag="VQ879_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3142472.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ879_000243"
     CDS             34282..34827
                     /gene="pgsA"
                     /locus_tag="VQ879_000243"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3142473.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34824..35651
                     /locus_tag="VQ879_000244"
     CDS             34824..35651
                     /locus_tag="VQ879_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3142474.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35636..36475
                     /locus_tag="VQ879_000245"
     CDS             35636..36475
                     /locus_tag="VQ879_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3142475.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36468..37262
                     /locus_tag="VQ879_000246"
     CDS             36468..37262
                     /locus_tag="VQ879_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3142476.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37321..38139
                     /gene="mreC"
                     /locus_tag="VQ879_000247"
     CDS             37321..38139
                     /gene="mreC"
                     /locus_tag="VQ879_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3142477.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38139..38633
                     /gene="mreD"
                     /locus_tag="VQ879_000248"
     CDS             38139..38633
                     /gene="mreD"
                     /locus_tag="VQ879_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3142478.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38727..39905
                     /locus_tag="VQ879_000249"
     CDS             38727..39905
                     /locus_tag="VQ879_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3142479.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ879_000250"
     CDS             40129..40908
                     /gene="rpsB"
                     /locus_tag="VQ879_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3142480.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            40987..42027
                     /locus_tag="VQ879_000251"
     CDS             40987..42027
                     /locus_tag="VQ879_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3142481.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ879_000252"
     CDS             42273..42560
                     /gene="tnpB"
                     /locus_tag="VQ879_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3142482.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42751..43019)
                     /locus_tag="VQ879_000253"
                     /pseudo
     CDS             complement(42751..43019)
                     /locus_tag="VQ879_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43016..43414
                     /locus_tag="VQ879_000254"
     CDS             43016..43414
                     /locus_tag="VQ879_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3142483.1"
                     /translation="MDAPIPKAPLAHSFGSASIIAHIIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(43611..44531)
                     /gene="cysK"
                     /locus_tag="VQ879_000255"
     CDS             complement(43611..44531)
                     /gene="cysK"
                     /locus_tag="VQ879_000255"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3142484.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(44816..45451)
                     /locus_tag="VQ879_000256"
     CDS             complement(44816..45451)
                     /locus_tag="VQ879_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3142485.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            45507..46805
                     /locus_tag="VQ879_000257"
     CDS             45507..46805
                     /locus_tag="VQ879_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3142486.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            46802..47464
                     /locus_tag="VQ879_000258"
     CDS             46802..47464
                     /locus_tag="VQ879_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3142487.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            47544..48092
                     /gene="raiA"
                     /locus_tag="VQ879_000259"
     CDS             47544..48092
                     /gene="raiA"
                     /locus_tag="VQ879_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3142488.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            48228..50201
                     /locus_tag="VQ879_000260"
     CDS             48228..50201
                     /locus_tag="VQ879_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3142489.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            50198..50650
                     /gene="rplI"
                     /locus_tag="VQ879_000261"
     CDS             50198..50650
                     /gene="rplI"
                     /locus_tag="VQ879_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3142490.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            50694..52046
                     /gene="dnaB"
                     /locus_tag="VQ879_000262"
     CDS             50694..52046
                     /gene="dnaB"
                     /locus_tag="VQ879_000262"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3142491.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52048..52314
                     /locus_tag="VQ879_000263"
     CDS             52048..52314
                     /locus_tag="VQ879_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142492.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            52403..53749
                     /gene="cbpD"
                     /locus_tag="VQ879_000264"
     CDS             52403..53749
                     /gene="cbpD"
                     /locus_tag="VQ879_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3142493.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     regulatory      53832..53934
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54005..54295
                     /locus_tag="VQ879_000265"
     CDS             54005..54295
                     /locus_tag="VQ879_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3142494.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54258..55016
                     /locus_tag="VQ879_000266"
     CDS             54258..55016
                     /locus_tag="VQ879_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142495.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            55054..56061
                     /locus_tag="VQ879_000267"
     CDS             55054..56061
                     /locus_tag="VQ879_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3142496.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56061..56789
                     /locus_tag="VQ879_000268"
     CDS             56061..56789
                     /locus_tag="VQ879_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142497.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            56908..57366
                     /locus_tag="VQ879_000269"
     CDS             56908..57366
                     /locus_tag="VQ879_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3142498.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            57368..59800
                     /locus_tag="VQ879_000270"
     CDS             57368..59800
                     /locus_tag="VQ879_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3142499.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60442..61095
                     /gene="rr06"
                     /locus_tag="VQ879_000271"
     CDS             60442..61095
                     /gene="rr06"
                     /locus_tag="VQ879_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3142500.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61092..62423
                     /gene="hk06"
                     /locus_tag="VQ879_000272"
     CDS             61092..62423
                     /gene="hk06"
                     /locus_tag="VQ879_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3142501.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62506..63033
                     /locus_tag="VQ879_000273"
     CDS             62506..63033
                     /locus_tag="VQ879_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3142502.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63112..>64454
                     /locus_tag="VQ879_000274"
     CDS             63112..>64454
                     /locus_tag="VQ879_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3142503.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNG"
BASE COUNT        20215 a        10986 c        12758 g        20495 t
ORIGIN      
        1 ttatttttcg tcattcattt ttgactttac ttcatcatag gatagtgcat gagattcctc
       61 ttctactgct tcaggcatct ttcctgtttc gtaaagagct ttaatttgtg tactatccaa
      121 tgtttcgtat ttcaataatg cttctgcaat taacttgtga atttcacgat ttgactgaat
      181 aatttcagca gctttatttc gtgcctcatt taataatgaa cgaacctctt catcaatttc
      241 ataagctgtt tgttctgaaa ttgatttttg aggactctgt gcaccaaaca tagcatggtt
      301 tccttcatat tgtactgggc caagtttttc actcataccg tactctgtaa ccattgcacg
      361 cgccatttgt gtcgcttgtt caaagtcgtt tgaagctcct gtagtttgga cattaaagat
      421 aatttcttca gctacacgtc cacccattaa gccagccaat tgctctttca tatcttcttt
      481 agatagaagc atttgatcct ctttaggaag tgcaatcatg tatccgcctg cacggccgcg
      541 tggtacaatt gtaaccttat ggacaacgcg agcattcgac aagactagac caacaatggt
      601 atgtcctgcc tcatggtaag caaccaattc tcgttctttt tgtgaaactg tcttatcttt
      661 cttagaaggt ccagcaataa ctctatcttc tgcttcatca atatctgaag catcaattat
      721 cgatttattg cgacgagcag caactaaagc tgcttcattc aagacattct ctaaatcagc
      781 accaacaaag cctggagttt gttgagccac taatttcaaa tcaacatctt ctgctaaagg
      841 cttgttctta gcgtgaactt tcaagattgc ttcacgacct ttaacatcag gacgaccaac
      901 caatactttt ctatcaaaac gtcctggacg caaaagggca ggatcaagta catctgaacg
      961 gtttgtcgca gcgatgacga taatcccttc atttccctca aaaccatcca tctcaatcaa
     1021 aagttggttc aaggtttgtt cacgttcgtc attacctccg ccgagaccga ctccacgttg
     1081 acgtccaaca gcatcaattt catcgataaa gatgatagct ggtgctgctt ttttggcatc
     1141 ctcaaaaaga gagcgaacac gactagctcc aactccgaca aacatttcta caaagtcaga
     1201 acctgagata ctaaagaatg gaacacctgc ttctccagcg actgccttag caagcaaagt
     1261 tttacctgtc cccggaggtc cctccaaaag aacacctgct ggaatacggg ctccaagttt
     1321 tgtgaatcgt tttggatctt ttaagaactc aacaacttca actagttctt gtttttcttc
     1381 ctcagctcca gcaacatctg aaaatcttac tttaatatct tctttatttg ctgctttagc
     1441 cttactacgt ccaaaactca ttggattacg gccattgcct cctcccatat ttcccatcat
     1501 agagaatagg aagaagaata gaattccaaa tggcacaatg gatacgagta gattaatcca
     1561 tataccactt gaactttcat gcttaacagt tacttctgct ttatggtcag tagcaagttt
     1621 ttgcaattct gatacggtag tatctgcagg aagaatagtg ctggtaaatt tctctacctt
     1681 agtaacagat ggcgtgaaaa actgaatacc tgtttcttct ttacttgttt taggattttt
     1741 atagacacca gaaacttcga taacactacc atttggttgg taagttaatt cttttacatt
     1801 accatcggta atttcttgta ccaactcagt atagttgatt tgctgacttc ctcctgagtt
     1861 attcccagaa tagaaatact ggaatcctgt cacaaggaaa aagataaata ataaccatag
     1921 aaaaggattt ttaattaaac cattattttg ttttttcatt aaagattatt ctttctaatt
     1981 tgaatacact tcctctttca atactccaat ataaggaaga ttacgataat tttctttgta
     2041 gtctaaacca taacctacta caaactcatt tgggatagta aagcaggtat agtctgcctc
     2101 aatttctaca acacgtcctt ctggtttatc caacaaggtt gcaattttaa cagaagctgc
     2161 ttctcttgct ttaaacatat ctcgcaaatt cttcaaagtt tgacctgtat caatgatatc
     2221 ttctacaaat agaacatgtc ttcctttgat atcttgagtc acatcttgtt taatattgat
     2281 aacaccacta cttgctgttc caccatggta gctagaaacc atcatgaagt ccatttcaat
     2341 atgtgtatca atatgtttga ccaattcagc cataaaagga atagatcctt ttaaaatccc
     2401 aactaagatt ggattttttc ctgcatagtc tttagttaat tgagcaccta gttttttagc
     2461 tgcttctgta atttcatcgt gtgaaacgag gactttttta atatcgtttt ctaacatttt
     2521 ttacctatct attttttcta tataaagtac agtgttcatt atatcatttt tcgttttttt
     2581 actcaaatta ttggtcgcaa ttcccaaaat tgagacaatt tcaccaaatt gctcaataat
     2641 aagagcagag tttctctttt ccatagggat tttcaaatca ataaataaac gtctgagttt
     2701 ttttctatgc ccattttgaa tcaaaacatc tcctgttttt cgatgacgaa tgtgtatgga
     2761 tgtttcacgt gaaacaggta tttgttgaat tgattcacct tctaatggaa gtccaaagga
     2821 aaataaatat ccttgataag ctacctgatt ttgatagtgt aacacaagtt catcttcctc
     2881 ttcatcagcc tgcggactga ttttacaaat ctgaaactgt tggtactctt ttatcaattc
     2941 atagccattt ttaatcggat gacgatactg gcttttagat tttaaaatct gctgaacttc
     3001 agcaaactga gcttttgtaa gattcaaatc tggaaaacga ttcagataag tttgaagtaa
     3061 aactctttgt gtagactcag agtaagaaaa taactgctgt aaatcttcca cattaatatt
     3121 gttagataat tcagctattg ccaaatcata atctaaaatt tcattgccaa tgcctaagat
     3181 tgcatcccta aatcgaggat tttctttttc caattctggt aagtaagagt ttcgaatacg
     3241 atttcgaaaa taatgattct cctgatttga tgtatcttca aagtgaaaaa ttgatggaaa
     3301 gtcttttttc tgaaaatgca agaagggacg aatgatttct atctctccga ctacttgctt
     3361 ctccttaatt cctgatagat agcgcaagcg agttcctcga atcaagcgca tcaaaatcgt
     3421 ttccacctga tcatcagcat ggtgggcagt gactaaagct gtcgcacctg tctttttcat
     3481 gacctcttga aaaaaatcat aacgaaaatt tcgtgcacgc gcttctgaaa attctcctga
     3541 aaaattgctg atataaatag gaagctctgc ttcagcagcc aacttcctta attccttttc
     3601 ttcccaatct gattcaattc tctgcttatg attcacatga gctagaatca attcaatctc
     3661 taactctttt tgataagtag acaatacctt aaatagaaac atggaatcta atccaccaga
     3721 aagagctaga accgccttag catgcttttt gaaatatccc ttcttgagaa aatgatttaa
     3781 aaaatctggt tccctcattt tagaacctca taaacatcct tggctatctt agaaatcgta
     3841 tcataatcag aattcttagt gaaaatagaa agaataaatg gagaatctgc atagacaaca
     3901 cccgtatcat gcttaaattc atccgcatct ccaattttat gagctacttt aacagaaaca
     3961 cctttggcaa ttcgctgact atcaaaatct gttttagtca aagactctaa cacaaatcca
     4021 ttttgattat aaatagcttc cataaacttc ccggccatct tagaagaaat caatttttct
     4081 tttggatccc aatcatctcc cataatggca gacatcttgg atttgaatgt ggcatcagat
     4141 tggtttgaaa tgtaatatcc caatagatta tgagctacat tatcagattc ttttgatact
     4201 ttcgtaatta aatcctttaa agaatattct ttattatctt cttttttagg aagactacca
     4261 cttccctctg gtttataaga acctggaaaa tcattgactg cagatacgta ttttacagtc
     4321 gtatctaact gataaagacc ctcatttatt ttttcttgcg tataatagag ataagagagt
     4381 ttcaaaacgc tggctgcata catcttttca tcttgattga taccagcttc ttttccagta
     4441 gtcagttgct taacataaat agagaaagaa tctttctgat atttttcaga taacatttct
     4501 tgaactttac tcatccgatt atcttcttca gaagttgatt ctttagctac ccatccagcc
     4561 tgatcaatat gtagaaattc tcttccttct acaaacatgg tcttgtcgat tgatacttgc
     4621 gaataagctg ataaggatga tttcacttct tttaaatcat aaggactatt gtacagttta
     4681 aagtcagatt ctaaccatgc tttttttatt gttggagtta cctctgattg atcatataaa
     4741 aatcgtttgt ccgcagctat aaattgatga tttgatagct taaatactgg aattccttgt
     4801 ttatttaagc gccactcggt tatttgaaaa cttgttttgg gagtcaattt cccagattcc
     4861 actactaaat cttcattcgc ataaacagga acctctccat aaaccatggg agaacttaat
     4921 ttttctctaa aataaatacc aaagtcagat tgtgaaaggt aataaatttc tttcgaagta
     4981 tagacgactt ctttttctgt actaacgact tttgaaatgg tcaaaaaact tggtagcaac
     5041 aaaataatta agaatttacg cattcttcct ttccttttct tcttgtaaac gcaataattg
     5101 atttttatca gccaattctt ccagcttttc atctgacaaa ctcaaaaatt gctctattac
     5161 gtctaataaa ttttccattt tatcaccttt gaagcaagtc aggaatcgta taaacttttt
     5221 ccctcgactt agaataatag tacttcgctc gtgtatattt ggcagcataa tcttcatctt
     5281 tcaacttggt agcaaatgct gtctccttat ccttttcatc actcaaagtt tgatactgag
     5341 tttgcaagtc tgctaattgc tgacgtcttt ggagtaattg ctgataactc tgcgctaaat
     5401 taaaagttgg caagataaat aatagcataa tcaaaatcaa tacccctccc ataaaacgat
     5461 tccgtttttg tcgttctttc atcaggtagc gacgacgttg gtattcattt tgaataaaag
     5521 aattattcaa ttgtacaata tttttagaca ttttcttcta cccgtgtttc actgataatt
     5581 tcatacattc ctgctgcatc ttcttttttt gtactatctt tcatctctag tacttttaca
     5641 agcagcaact tattgccaaa gcgaatttca acttggtcat taactttcaa gtccgttgaa
     5701 cttttggcca agattccatt aaccttgatt ctacctttat ctgctacttc ctttgcgact
     5761 gtacgacgct tgataattcg cgatactttt aaatatttat ctaatctcat ccttattacc
     5821 tcaatttatt attgtaccat ttttatctat tttatagaag aaaaatatca aatggaattt
     5881 tcttccttag actcttttat ctctaataaa ctttctccaa aaatcagcag accttctaaa
     5941 atttcataat ctttcttatt ttggacatca aatacaagct ccattaatcc cttattctca
     6001 gcgatgcctg cttttaagtt cgttacggat aaagctttaa aataatcttg agctaaaaac
     6061 aatcgttgag tgactttttc aaattgaatt gtaattttat tatcttttct ttccacacgt
     6121 tgaacaaaga ccttgtccaa gtatgattta accaaaccaa tctctaaaag ataggctact
     6181 acatctgggt attctccaaa acggtctatc aactcctctt gtaactcttc ataattgaca
     6241 cggttgtcaa tttgacgaat tttcttgtaa atttcaatct tatgtcgttg atcagaaata
     6301 taagtatcag gaagataggc atcaatttgc aaaatcaact cagcattccc tttggttctt
     6361 gtgttagcgt tagcattacc gtttcgttta gcaatagctt cctctaataa ctgcgaatac
     6421 aattcaaaac caacagaatc aatgaaacca gactgggatt ttcctaaaag atttcctgct
     6481 ccacgaatcg aaagatctcg cattgcaatc ttaaagccag agcccaattc tgtaaatcct
     6541 ttaatcgctt ctaatctctt ttcagagact tcactgattg atttttctgg acgatacatg
     6601 agataagcat aagcaatacg attactacga ccgactcttc ctcttaactg atataaggtt
     6661 gacaagccca tatggtccgc attttcaata aataaagtat tagcatttgg aatgtccacc
     6721 cctgtctcaa taatagtagt cgtcaccaag atatcgtatt gtccctcaat aaagtctaat
     6781 agagtatttt ccaactggac ttcactcatt cgaccatgaa catatccaat cgaagcctct
     6841 ggaatcaact cctgtaattc tgaaaccttc tgaacaattg tatcaacttt gttgtaaaga
     6901 taataaactt gacctccacg ctccatttca cgcaagacag catcacgaat gacactatca
     6961 ttcttttcca aaacataggt ctgaacagga tagcgattag tcggcggagt ttcaataaca
     7021 gacaaatctc tgattcccag catagacata tggagggtac gagggattgg cgtagcggtc
     7081 aaggttagga catccacttg tttcttcagt tctttcaaag tttccttatg cttgacacca
     7141 aatcgctgtt cctcatcaat aatcatcaag cccaaatcag caaacacaac atcttttgac
     7201 aaaacacgat gtgttccaat caaaatatcg acttgaccgt ttttcaattt ttcaagtgtt
     7261 gcagtctgct cttttttact tctaaagcga ctcaacacat caacattaac tgcaaaattt
     7321 tggaatcgtt ccttaaaatt cgtatagtgc tgttgcgcta aaaccgtcgt cggaactaga
     7381 atgacaacct gtttgtgatc attgactgct ttaaaggctg cacgcatagc aacttcagtc
     7441 tttccaaaac caacatcccc aactaaaagt ctatccattg gctgagaagc ctgcatatcc
     7501 ctcttgattt cctcaatact acgaagttgg tcatccgttt caacataagg gaaagcatca
     7561 tcaaaggcat cttgatcatc atcatcagct gagaaagcaa aacccttcaa ctgactacgt
     7621 tcagagtaga gtttgattaa atcatcagct atatcctcta cctggttctt aaccttttgc
     7681 ttggcctttt taaaatgacc gtcatttaat ttattgagtt ttggagcttt accatcactt
     7741 gaaatatatt tggacagtag atgaatctgt tccacgggaa tagaaatttg atcaccattt
     7801 tggtattgga cactgacata atcacgatga attcccttga tttcaatggt ttcaattcct
     7861 agatattgac caatcccatg gatatgatgg acaacatagt cccctttttc aagttcattg
     7921 taatctttta atctctctgc atttgaaaca tgttgtcttc gaaaacgacg ctttaatttc
     7981 ttttgaaaaa tctcatgttc agttatcaat aaaatctttt catctacaaa atgaaaacca
     8041 tgtctgagat taccttctat taagtttaca gattctttac agatacttgt cttatctcta
     8101 gaatccaatt taatctgata ttcctctaac atatcctcca atgttttact tcccattgaa
     8161 ttgctagact gcagaataat ggtgtaatcc atttttttat atcgttcaat ttcttctttt
     8221 agaaaagaaa actgattgaa aaattcctgc ataggatatt gattgaattg ataaattttg
     8281 tcaaatttga gatttcctaa acccttttga agattagaga aaaaggtcac tggactttgt
     8341 tttttataga tttgttcaat atcagaaaaa tactgcatat cagaaaatgc tttactattc
     8401 tgtaattctt ctgtaaagta ctgcgctaat tctctttcaa agacttcata ctgattcatc
     8461 aatttttgat aatcatcaaa gaatattgga gtatcttttt caatataatc aaagacagtc
     8521 catgtcttat catagcacaa agataaaaac ttccgagaat ctgcatgact ttgcttttga
     8581 tgaaaacttg aaagaatttc ttctaggtat gatttcaaaa taggtgataa agtttttgaa
     8641 atttgttttt ctaaagctga ctgtcctcgt tgataatcct tttctctcaa aagcatatca
     8701 ctagctggaa agatagtgag ttctgtctta ttttctttcg ataattgtgt ttctacttca
     8761 aatgacctga taccatcaat ttcatcacca aaaaactcaa ttcgacaagg ttctaactgg
     8821 gatatttcaa aaatatctaa aatatctcct cgaagactaa attcaccctg agtttgtact
     8881 tgagtaactt ttcgatagcc attttccttt aactgatgga taaacgcgtg ttgagcatat
     8941 tcttcaccaa ctgagatttt tacaatacta tctttgaatg cattgggaga cggtaaaatc
     9001 aatcgacttg ctgcgatatt acaaactaaa atccctttct tagatgaatc agtcaaaaaa
     9061 cgcaaggctt caacccgtga aataattttt tcctgtgaag acatcaaaaa ctccaccata
     9121 ggagcatcat ctaccaaaaa tggatagacg agttcctcac ccaagataga aataagatca
     9181 ctaacaagtc cttctgcttc tccataagtt gacgtcaata acacaatcct atcttctttt
     9241 tctaaactgc ttgcaattgc aagagcctta gtagatgttg ataaaccaag tattagttgt
     9301 cttttcttat ctgttaaatt ttgatgccat tttttaatct gatcattttc tgagaataaa
     9361 tctaataagg tcaccattta tccgttatac ctctgcattg ttttctcaaa atttttctct
     9421 tgtaaatagt agtttacaga atcgtcaact ttgtcaacag actgtaaaat accgatataa
     9481 tcatccctgt caaacttact caaaacatga tgaacaactg acataccatt tttaggtctt
     9541 ccaattccaa tcttaacacg gttaaagacc tgagttccta tatgttgaat aatagacttg
     9601 ataccattat gaccacctgc tgagcctttt gctcttaaac gaattttccc aacttccatg
     9661 tcaagatcat cgtaaatgat aagtaaatcg tcaatatcca aaccatagta agttaataaa
     9721 gcatgaactg cttttccact ttcattcata aaggtcgttg gtttaaccag ataaattttt
     9781 tctccattta ggaaaaagga tgctaggtca gcttgaaata tcttatcgtg tgtaaaagtg
     9841 acattctgtt tcttcgctag ttgatcaatc aacataaaac caacattgtg ttttgtttca
     9901 aaatatttat cccctggatt tcccaagcct acaagtaatt tggtcattta tttttccttt
     9961 caaaagccaa aagggttgga atttttttcc aacctaattg acaccattta ttaattttta
    10021 gacattaaag cggaattcca tgatatcgcc atcttgaacg atatattctt ttccttcttc
    10081 acgcaagcgt ccagcttctt ttacggcctt ttcagatccg tatttcacta gatcttcata
    10141 tgacatggtt actgcacgaa taaagccttt ttcaaagtct gagtggataa taccagctgc
    10201 ttgaggagcc ttcataccac gtttgaaagt ccaagcgcga acttcttttt caccagctgt
    10261 gaagtaagtt cccaatccaa gcaagtggta agctgcacgc gtcaacttat ctacacctga
    10321 ttctgtcaaa ccaatggctt caagaaactc ttttttatct tcatcatcca attcagaaat
    10381 ttcttcctca gcacgcgcag aaataacgac tacttcagca ttttctgtcg ctgcaaattc
    10441 acgaatttgt ttgacatagt cgatagagtc aggttccgaa accacatcct catccacatt
    10501 agctacataa agaactggtt tagtcgtcaa aaggaaaaga cctttgacaa ccttttgttc
    10561 ctcatctgta aattcaatgg tacgagctga tttcccatct tctaggactg gtttaatctt
    10621 ttgaagaaca ttgaattctg ctactgattc tttatctttt tgcgtacgtg ccatcttttc
    10681 tacacgcgca tatcgtttgt tcactgattc taagtcagca agaatcaatt ccagattaat
    10741 ggtatcaata tctgcaagcg gatctacaaa ggcgtcttca cgtccttgct cgcgcatcac
    10801 attttcatca tcaaaagcac gaactacgtg aacaatcgca tctacttcac gaatattggc
    10861 caagaattta ttccctagcc cctctccttt tgaagctcct tttacaatcc ctgcaatatc
    10921 tgtaaattca aatgttgtgg gaactgtctt tttaggagtt atcatttcag ttagtttttg
    10981 tagacgttca tctggaactt ccaccattcc aacatttgga tcaatcgtcg caaatgggta
    11041 gtttgctgcc tctgctcctg cttttgtaat tgcattaaat agtgttgatt taccaacgtt
    11101 tggcaaacca acgatacctg ctgtcaaagc catatttctc attctccgtt ttcatttcaa
    11161 tccctaatat tataacacaa aaagggataa agtgctaacc ctctaactaa gggttctcag
    11221 tcaataattt tattcatttt tcgctcaaaa tcatatcgcc ccatcatgac aacatgctca
    11281 caattactgc attttatttt gatatctgct cctacacgtg taatttccca acgattagcc
    11341 tttttaccag tcgacttgat tgtacaagcg tgtggttttt tcatctcaac aaaatttcca
    11401 acttgataca tactactctc cttttctttt tcgattatat cataaaagag gcgagccagg
    11461 ctcaacctct ttcacttaat ttgtacgaac tggtgtaatg agctgcatga agtcttcgtc
    11521 agtatctgct ggcacaagag taaatggacg aacagctgag ataaagctaa tggtcacctt
    11581 ttcgctattt aaagctttaa gagaatcaat caagtaagtt gggttgaaac taatggtcaa
    11641 atcttcacca gtaacctgat cagtatcgat ttcttcgttt actttaccaa cttctggaga
    11701 gtgaacatgg gcgctaacaa ccccatcctt aatttcaagt ttcacagtac cattttgagt
    11761 cgcacttgat aaaagacggg cacgctccat tgactggcgt aagtttacca cattaaaagt
    11821 aatagtagtg ttaaagtctg ttggaatcaa gcgatctgta tcaggatagt ttccttctag
    11881 gagacgagta tagaagctaa tattttcgct tctaaagagg atttggttat tggcaaagaa
    11941 aatctctaca gtttcgatat catctgtaaa taccgctgaa aattcgcgta gagaacggct
    12001 aggaattacg acatcaaaat catcactatt tttttcaaga gtcaattttt tctggcttag
    12061 gcgatgagag tctgttgcaa ctgtttttaa ctctttgtgt tgactcaata cgaagtggac
    12121 acctgttaaa atcggacgac tctcttgtgt acttgcagca aaggctgttt cattaataat
    12181 tttcttgagt aattttgttt caagtattaa aggagtgctt gctgaaattt cttggattcg
    12241 tggatattgt tcgctatctt ttccttttag ggtaatttct gatttgccac tggttaaaac
    12301 aatttgattt tgttcaattt ctttaaaatc aagagttaca tcaggtaaac tagatactac
    12361 attgataaag aaagaagctt caagaaggat cgaacctaaa gaagtaatca acaaaccagc
    12421 atcttcattt ttttgagaaa taaaattttc aattgagatt tgaccatttg aaccaattaa
    12481 agtaatacct tcattggtca cgtcaatttt tactgttgat aaaataggaa tggcattttt
    12541 agaactaata gctctcttag tagtatttaa tgcttgtaga aataaatttt tattaattga
    12601 aaaatgaatc atggattctc ctttatttat ttttagtatt agaaagataa tagtaataat
    12661 agagtctgtg aaatctgtgg aaaacagcct ttaaacaagt cctatcaagt tttttagctt
    12721 gtttaaaaaa tgtggataaa aaagataaaa aactaaaagt tatccacaaa ttatttgatt
    12781 ttctttttga ttgattcaat ttctaaacgt aaattatcgt cttgatcaat caaagatttt
    12841 attttggcat gggcatgaat gactgtggta tgatcttttc ccccaaattc cttcccaatt
    12901 tttggaagac tattatctgt tagttctcta gataaataca tggctacttg acgggccaaa
    12961 acaatatttt gaaggcgtct acttcccttc atttctttga tactaacacc ataaaagtta
    13021 ccaacttcag tttggatttt atcaattggg atgacgagca tttggctaac atcttgtttg
    13081 cgggctctaa tggcttctgc agcaatatca atagtgatat ccttgatttt ttttactctg
    13141 gcaattaaag tgatgtcgtt gatggctccc tcaagatctc gaacatttga atcaaattgc
    13201 ccagctaggt attctagagt atcactttgg aaattgtagc ctaaatgttc cgttttactt
    13261 tgtaaaatgg caatacgtgt ttcaaagtca gggggtgtga tagtttgtgt caatccccaa
    13321 ctaaaacgcg tgacaagcct ctcctcgagc ccttctagat gttttggact acgatcactc
    13381 gttaggacaa tctgtttttg cttgtcatga agggcgttaa aggtattgaa aaattcttcc
    13441 tgagttgcga ctttttttcc gctgagtgac tggatatcat cgattaacaa aagatcaaga
    13501 ctacgatagg tctttttaaa cttttccatt tccccaagtc ttaggtgatc aagaaagtca
    13561 ttaataaagc tttcggcagg gatatattta acacgcgcat taggaatatt ttttagaatt
    13621 tcatttccaa tagcgtttaa taagtgagtc ttaccaaggc ctggtcctcc atagataaaa
    13681 agagggttat aggtcagagc caaatcttca gagacagcta aagcggctga tacagcccaa
    13741 acatttccat ccccttgaat aaagttatca aaggtatact tttcttttaa tcccgtatct
    13801 gaataaggaa tagatactaa ctttggacta tagtcataaa gagttaaatt tgtagcttct
    13861 tcaacttgtg agctagtcgt atcttgaggt ttggtgaaaa tatagtgggg agttatttca
    13921 gcgtcataaa tttcaaaacc agctactaca ataatatctt ttagttgttt ttcccagacc
    13981 atttccattt cagagcgagg tagaaatata gtggcaacat tttcctctac cttgataact
    14041 tcagcttgaa tagcatagaa atcatacatg gatcgagtca gtctttcttg tgcaaattct
    14101 aatatacgat tccaaaattg tttttctttc aatcctttct cctcctttac tatttaaaag
    14161 tttaatacta gagatatttt accatagata gcaagaattt tccacaagct gtgaaaaata
    14221 atccacaatg ttaccaaact ttatccacag gttggggata aaagaagaaa ttattgattt
    14281 attaagcttt ttatcgaaaa acatagtgga taaccttgtg agataaaaaa ataaaagaac
    14341 agccttattt caggctgttg ataattctac tatattcttc ttgatttgaa aaagaaataa
    14401 tgatttttcc actgtctttt ttagatagtt taatttctac atctaatccg agtagttttc
    14461 ttaactgttt ttcttcattt tgtatgaaat gattagtttt ttgctgtttc ttttgttttt
    14521 tctctgtcag aagagcttct aatttcctta cagaaatatc ttcttctata atccgttgaa
    14581 agaaatagtc ttgttgttcc ttatttaacc caactaggga acgcgcatgg gcttgtgata
    14641 gtttgccatt ttctacttct gaaagaatct gttctggcaa ggaaagtaaa cgaatggagt
    14701 tgctgatata tggacgagac ttgcccatct tatctgcaat ttcagcatgg gtgaatcctt
    14761 tctctacgag agattcatag gcgcgtgctt cttctattgg gtttaaattt tctctctgta
    14821 aattttcaat aatggactgg accatcatct cttggtctga aatctgttta acaacagctg
    14881 ggatagaccg tagaccagct aaaagtgaag cccgatagcg tctctctcct gcaaggattt
    14941 cataaccaat aacaggagat tgacgaacaa taatcggttg aatgacccca ttttctttga
    15001 tagactgtgc tagttcatct agtttttctc tatcaaattc ttttcggggt tgatagggat
    15061 ttttttgtat atctgtgata gaaatcattt caaatttttc catgattcta cactaacaca
    15121 tcttttctct tatgtaaagc tttctttaca tagatgtcaa ttaagattct aaatcacctg
    15181 aactcttgtt aagtttgata gaggtagttt cttctttccc gttacgatag taggttatct
    15241 taatggtgtc tccgatagaa tggttgtaaa gagcactttg taagtctgtt gatgaagcaa
    15301 tctctttgtc atctactttt gtaattacat cgtatttttc aaggtgacca ttggcaggca
    15361 tattactttg taccgaacga acaattacac cagatgtaac attacttgga atattgagtc
    15421 ttctgatgtc gcttgtactc acattagata aattaaccat ctggattccc aaagctggac
    15481 gcgtcacttt tccgtttttt tctaactgtt caataatatt gatagcatca tttgcaggaa
    15541 ttgcgaaacc aagaccttct acagatgttc ctccatttgt agcaatttta cttgaggtaa
    15601 ttccgataac ctgcccttga atattgatca gtgggccgcc agagttacct gggttaatag
    15661 cagtatcagt ttggatggct tttgtagaaa tagcttgtcc atcttccgat tttaaggata
    15721 catttctatt gagactggat acgatacctt gagtgacagt atttgcatat tcagaaccta
    15781 acgggctacc gatggcaata gcagtttctc ctacagttaa cttactagaa tcaccaaact
    15841 cagctactgt tgtcactttt tctgaagaga ttttgacgac agcaatatca gagaaagtgt
    15901 cagctccgac aatttttcca ggtactttag tcccatctga caatcgaata tctactttgc
    15961 tggcgccatt tataacgtga ttgttggtga cgatgtaagc ttctttatca ttctttttat
    16021 aaataactcc agatccttca ctagagattc gctgagaatc tgtgtcagta tcatcattgc
    16081 caaatacgct attttgtctg tttgccgaat aagtaataac agaaacaaca gcatctttta
    16141 ctttgttaac agcctgtgtt gttgaatttt cgttcttata ggcagtttgt gtaatagtac
    16201 tattgttgtt agagttgttt acactacttt tttgagttag ttgagttatt gaaaaactac
    16261 ccaaggctcc actaaaaaag ctaatgacga taacgactaa taattgaaac cattttttgt
    16321 aaaatgtttt tagatgtttc atatttgcct ccatatgttt gaattactga aagtataaac
    16381 tgactagctt aattataact taaacacaaa agttttacac aaactgtgga taactctttt
    16441 gaaattgtga ttttcttaat tgaaatctat tttttatttt gtgaataaga tgtgaaaaaa
    16501 tagagaatat gttagaatag agtcatgaaa attaaagttg taacagttgg gaaactgaaa
    16561 gaaaagtatt taaaagatgg tatcgcagag tattcaaaac gaatttctag atttgctaag
    16621 tttgaaatga ttgagttatc agatgaaaaa acaccagata aggccagtga atcagaaaat
    16681 caaaagattt tagaaataga aggtcagaga attttatcaa aaattgctga ccgtgatttc
    16741 gttattgtgt tagccattga agggaaaact ttcttctcag aagaatttag taagcagtta
    16801 gaagaaactt ctataaaagg attttctact cttactttta ttattggggg aagtttagga
    16861 ttgtcatcat ctgtaaaaaa tagagccaat ctttctgtca gttttggtcg cataacctta
    16921 ccccatcagt taatgagact agttcttgtt gaacaaatct atcgcgcttt tacgattcag
    16981 cagggattcc cctaccataa atagaaaatt gacttttaat tgaatttttg gtagaataat
    17041 tgtattaggt ctcatagctc agctggatag agcattcgcc ttctaagcga acggtcgcag
    17101 gttcgaatcc tgctgggatc aatataatag caaagctggg aattttcccg gcttttttct
    17161 taaaaaagta cactttggga gaaaaaaatg acagttgaga gaattttatc taaaacgaaa
    17221 ttccattttg tataatggtt tttgtaagtt agcttacaag aaaaaacatt ttaggagatt
    17281 ttattatgaa aaacacagtt aaattggaac agtttgtagc tttgaaggaa aaagacttac
    17341 aaaagattaa aggtggggag atgaggttgt caaaattctt ccgtgatttt attttacaaa
    17401 gaaaaaagta atgaaataag gggaaagagt aatggattta tttggatttg ggacggttat
    17461 tgttcatttt ttaattatta gtcacagtta ccattttatt tgtaaaggtc aaataaatag
    17521 aaaagaatta ttcgtttttg gtgcttatac attactaaca gaaatagtat ttgattttcc
    17581 cttatatatt ctatatttag atgggttagg gattgaaaga tttttatttc ctttgggatt
    17641 atattcctat tttcgatgga tgaaacagta tgagagggat agaggactat tcctaagttt
    17701 actactatct cttttatatg agagcactca taactttctg tccgtaactt tctcctctat
    17761 aacaggagat aattttgttt tacaatatca tttcccattc tttttcgttg tgacggtgtt
    17821 aacctatttt gttacattaa aaatcattta ctatttccat ttggaactag cctattttga
    17881 tgaggactac ctttatcctt tcttgaaaaa agtatttttt gctttactat tgctacatat
    17941 tgtatctttc gtttcagata tggtaagtac gattaaacat ttgaatagtt ttggaagtat
    18001 tttgtcatct attgtcttta tctctctcct tttgaccttc tttgcaatga attctcataa
    18061 agttcaaatg gagaaagaga ttgctttgaa gcagaagaaa tttgaacaga aacatttaca
    18121 gaattacaca gatgaaattg ttggtctgta taatgaaatc cgtggttttc gacatgatta
    18181 tgctggaatg cttgtcagca tgcagatggc aattgacagt ggtaatttac aggaaattga
    18241 cagaatttac aatgaagttt tagtcaaagc aaatcataaa ttgcgttcag ataagtacac
    18301 ttactttgat ttgaacaaca tagaagactc agctttacga agtttggttg ctcagtcaat
    18361 tgtctatgct cgaaataatg gtgtagagtt tacactggaa gtaaaagata cgattaccaa
    18421 gcttccaatt gaactattgg atttggttcg tatcatgagc gttttattga ataatgctgt
    18481 cgaaggatcg gctgatagct ataaaaagca gatggaagta gcagttatta agatggaaac
    18541 tgaaacagtt attgtgattc agaattcatg taaaatgacg atgactcctt caggagatct
    18601 atttgcctta ggattctcca ctaagggaag aaatcgcgga gtcggattaa ataatgtgaa
    18661 agaactacta gataagtaca acaatattat tttagaaaca gagatggaag gcagtacatt
    18721 tagacaaatc attagattta agagggaatt tgaatgaaag ttttaatttt agaagatgtt
    18781 attgaacatc aagtgagact agagagaata ttggatgaaa tttcgaaaga atcgaatatt
    18841 ccaatatcat acaagacaac gggaaaagtc cgtgaatttg aagaatacat tgaaaatgat
    18901 gaagtaaatc agctttattt cctagatatc gatattcatg gaattgagaa aaagggattt
    18961 gaagtggctc agctcattcg tcattacaat ccttacgcta ttatcgtctt tatcactagt
    19021 cgatcagagt ttgcgactct aacatataaa taccaggtat cagccctaga ttttgttgat
    19081 aaggatatca atgatgagat gtttaagaag agaattgagc aaaatatctt ctacacgaag
    19141 agtatgttac ttgaaaatga agatgttgta gattatttcg actacaatta caagggaaat
    19201 gatttaaaaa ttccttacca tgatattttg tatattgaaa caacaggggt atctcataaa
    19261 ttgcgcatta ttggtaagaa ttttgcaaaa gagttttatg gtaccatgac agatattcag
    19321 gaaaaggaca aacatactca gcgattttat tctcctcaca agtcattttt ggtaaatata
    19381 ggcaatatca gagaaattga tcgaaaaaac ttagaaattg ttttctatga agaccatcgt
    19441 tgtcctattt caagattaaa aattagaaaa ttaaaagata ttttagagaa aaaatctcaa
    19501 aagtgattga caattagcaa gaaattgata taatggttat atctgctaca gatagaaggt
    19561 ccgttggtca aggggttaag acaccgcctt ttcacggcgg taacacgggt tcgaatcccg
    19621 tacggactat tttatccgcc atagctcagt tggtagtagc gcatgactgt taatcatgat
    19681 gtcgtaggtt cgagtcctac tggcggagta tagataaaag ggaacacagc tgtgttcctc
    19741 tttttgtatc aatttgtatc accaagcatt ttcataagga agtctgttat ttcttgagaa
    19801 ctttcttttt ttccatgtgc aatccaagtt tggcagacac caaaaagtgc atgagttaga
    19861 tagatgctac tatattctaa ttcggtggta tttagattca gttgcataaa tcgcttttgt
    19921 aaatctgtac taagcatgat atgaagttta tttcgtaaga aattttggat ttctttagtc
    19981 ccattttcag aaagaagggc agccagaagt ggttctgact ctagatattc aaaaacttct
    20041 aaaatagcgt ctcttttgtg atgagcatgt ttttgaaaaa tatattcaaa tgtatggaat
    20101 agcttgcttt gatagtgctc aatcatatca tacttatcct tatagtgagt atagaagctg
    20161 gaacgactaa ttccggcttt ttctactaat ttgacagtag aaattttatc aaatggctgt
    20221 tccatcagta attgtaccat agcattttca atagttcgct ttgtttttaa gcgtttgtta
    20281 ctttcttgca tatttcctcc ttgtaaacaa attagactat atgtctaaaa atagattttt
    20341 tatcttgtaa tttagatttt ttaatgtata atctattata tcaaaatttt agacaatatg
    20401 tttaaaaaag gagaaactaa gtttaaagaa tggaaagcaa tttaaaaaaa accaaccttt
    20461 attattgtca tgatcgggat ttctcttatt ccagatctgt acaatatcat atttttgtca
    20521 tcaatgtggg atccatatgg gcaattgtct gacttacctg tggcagttgt aaataatgat
    20581 aaagaggctt cctataatgg taatactatg gcaataggaa aagacatggt gtccaattta
    20641 aaagaaaata aaaccttgga ttttcatttt gtagatgaag aggaaggaaa gaagggattg
    20701 gaagatggcg attactatat ggtagtgact ttaccaagtg atttatctga aaaaacaact
    20761 acattatcca atattcaatc gacagcagct tatcaatcat tgacaagtga gcaacaaact
    20821 gagataagtg attctgtatc tcaaaattca actgatagta ttcaatcggc tcagtcaatt
    20881 gtagctttag tacaagattt acagggaagt ttagaaaact tacaaaatca atcttctaat
    20941 ctttcgactt taaaaaatca atctaatcaa gtatcaccta ttacttctac ttctttgata
    21001 ggattgtcaa gtggattaac agagatacaa ggagatgtta ctagcaaatt agttcctgcc
    21061 agtcagtcga ttgcatcagg tgtaaacgca tatactacag gtgttgataa agtttctcag
    21121 ggcgcaagtc aactaagtga aaaaaatgcc accttgacag gtagtttgga taaactagtt
    21181 tcaggctcaa acaccttgac acaaaaatct tctagattga cagcaggagt tggttaatta
    21241 caatcaggat ctgggcaatt agcagacaaa tccagtcagt tactttcagg tgcttctcca
    21301 ttagagaata gagctaataa attggcagat ggatctagga aactagcaga aggtggaaca
    21361 aagttaactt ctggattgga agatttacag acaggacttg cttctttagg acaaggacta
    21421 ggtaatgcta gtgatcaact caaatcagta tcaacagaat ctaaaaatgc agagattttg
    21481 tcaaatccac tcaatctttc aaaaacagac aatgatcaag ttcctgtaaa tggaatcgca
    21541 atagctcctt atatgatatc agttgctctt ttttttgcag caatatcaac aaatatgata
    21601 tttgcgaaat tgccttcagg acgtcatcca gagagccgtt gggcttggtt gaaatcttga
    21661 gctgaaataa atggtattat agctgttttg gcaggaattt tggtatatgg aggagttcag
    21721 cttattggtt taactgctaa tcatgagatg agaatattta ttctcatcat cctaacaagt
    21781 ttagtattca tgtctatggt gaccacttta gcaacgtgga atagccgtat aggagctttt
    21841 ttctcactta ttttgctttt actacagtta gcatcaagtg caggtactta tccacttgct
    21901 ttgacaaatg atttctttag atctattaat ccctggttac caatgagcta ttcagtttcg
    21961 ggattacgac aaacaatctc tatcaacaag tcattttcct agctgtcata ctagctctat
    22021 ttactggttt aggtatgcta gcctatcaac ataagaaaat ggaagaagat taaaaaaatc
    22081 gaccgattaa ctggtcgatt ttttatgcct tagatgactt tcgtctgtga ttatagattc
    22141 caaatagtaa gagagaagta aaggaacaga ttgctccagt aataaaacca ttgggaatga
    22201 aggaaagtgt aatagttcct ttccccttgg gaatgtcaac tttcataaat ccagtttgag
    22261 cttgtttaat ttctattttc ttaccatctt ggtaggcaga ccaacctttg tcataaggaa
    22321 tggtgaagaa aatagatgta tcttgttgga catcatatgt agcaaaaacc ttgtttttag
    22381 aagttgatac tgtgacaggt tgttctttaa ttttttgaat tgcctcggtg aaagttttgg
    22441 tatctaaacg atagaaggta ggagattcaa atgatacttg tgaatttcca gggaaactaa
    22501 cattgatatt gaaagttttt ttctctttag tatatcctag attaaagaag gagaagacat
    22561 tatcagttgt aaaagtcttt ttttcaccat ttacaaggat gtcaaccttc ttttgtttat
    22621 cgttagaaaa gtgaaggttt atgaaagaga gataaacttg gctgttttct ggaacttcaa
    22681 tttgatactg gattgctgca tcttcatttg aagaacttgt gacactaatc aaatcattag
    22741 tattttctat tttttctgtt ttttcataag gtattggaga aaaataatca aaattgacgt
    22801 tagcaagttg atttaaaaat gaggcctgat tatccaaggt atgttcattg aacttgacat
    22861 cattgtaaac agattgacta gcaactgcaa tcggaagaga gtattgattt tcatataggg
    22921 taagattatc tttttgatag atatctttaa agccatactt atcaatagga ctgtctgaga
    22981 tattgtactg gataccaaat aaactatcag ccaaaatact attatttgca tatcggagat
    23041 tgagattagt cccagaggat ttaaaaccaa gtttatctaa agtagagctt gatgaacgat
    23101 ttcgaacaga tgaaaattga gagattccat tgtagttgaa tttcatactg tcatttcctg
    23161 tctgagtttg tagtttttca gtacgagtaa attgatttcc aatatatgtt gagaaagatt
    23221 ccatagctag gatatctcga ctataagcac ttcgagaagc aaatccccat tccttagcaa
    23281 ttccgtccat ttgagatgaa gcatttaaac tcatttcaac cagtataaat aaagagatta
    23341 gaatggcaaa tagattcaca gatataaact ttttgataac tgcaaggagt aaaagagaat
    23401 agacaaccaa aaattcaaga gtaagcagaa tattcaaatc tgttaaaaaa gaataatgcg
    23461 attttagata gatggtagct aaaaatcctg ctactacaag aaaaagcgaa actaaaaaat
    23521 tccagacttt aagttctttc agacgcttta agacttctgc tgctgtgtaa attaacaagg
    23581 tagagaaaat ccaagcatag cgatgtaaaa acatgtttgg agtatgcatg ccttgccaaa
    23641 ataagtcaag agcttctatg taaaagcttg caattagaaa tgcaaagaat attacatata
    23701 tgagtttcac gtgaaactta atagatttca gcgtaaaaaa taaaatggtc aaaataaagg
    23761 gaaatagtcc aacaaaaatc attgggatgg ccccatactt tgttgtgtca aaggaaccaa
    23821 tgaattgctt agcaaagaga tcaagatacc agctactttc agtttgaaac tttgtaactt
    23881 cagtcaattt ttccccatgt gtctgtaaat caaatagagt gggaagagtc ataatcaaac
    23941 tagccatacc agctaaaaag gagataacta tgaaatcaag aacagatgat tttcgagtct
    24001 taaagtccca cgaaatttga cagagatacc agaaaataag aaacaatact gtcatatatc
    24061 caaaataata attttgaata aataagattg acagacttgt aaagtacaat aggagtttct
    24121 tttcagttat cagtagatgt aaaccagtta taattaaagg aatcaagata aaaacatcta
    24181 gccaggtttt tatctctaat tgactgacag tgaaactcat cagagcatag gaagtagata
    24241 aggctagttt taaagtctga gggatagatt gaaacaattt attcaaacta aaaaaggttg
    24301 acagaccaat caatccaaat tttaagagag tggtcagata gacagcatct ggcatgttcg
    24361 ttagatcaaa aaagtaaact agaggcgcga gaaaactacc caagtaataa ctagataggg
    24421 catagaagtt tagccctaga ccacttgtaa aggtgtaaaa cagactacta tttccatgta
    24481 ggatatttcg taaggctaca tcaaaaataa cgtattgatg aaagccatct cctaatagag
    24541 gagagttgtc gctattccag tagatacctt gagatagata tactccagac ataatcacta
    24601 caggaatgat gagagaaata aaataggttc gatatgtttt taaaaatgat ttcatgttac
    24661 ctcgtagaat gatagaaaac tcagttggtt aacccaactg agttttgaag ttttatttag
    24721 tctttccaaa gttctttaac ttttgcttgt acttctgcat tttctaggaa ttcatcgtag
    24781 gtttcatcga tacggtcaat gacgccattt ttagataaga caatgatatg gttagccaaa
    24841 gtttgaataa attcgtggtc atggctagca aagatgattg attctttaaa gtttttcaat
    24901 ccatcattca agcttgagat agattccaag tccaagtgat ttgttggatc atcaagtaca
    24961 aggacatttg attttaagag catgagtttt gaaagcatga cacgaacttt ttctccccct
    25021 gacaagacat ttacaggttt gttaacttca tctccagaga agagcatacg gccgaggaag
    25081 ccacgtagga aagtattgtc atcttcttct ttacttgcga attgacgcaa ccagtcaaga
    25141 attgattctc ctcctgcaaa atcagctgag ttatcttttg gtaggtaaga ttgactagtt
    25201 gtaactcccc acttgacagt tccttcatag tcaatatctc ccatgattgc acgaattaat
    25261 gcagtcgttt gaatatcatt ttgtccaata agtgctgtct tatcatctgg acgcaagatg
    25321 aaactaatat tatccaagat agtttcacca tcaatcttta cagttagatt ttctactgtc
    25381 aagagatcat taccaatctc acgttccgct ttaaagttga taaatggata tttacgacta
    25441 gatggtacaa tctcttctag ctcaatctta tcaagcattt tcttacgtga tgttgcctgc
    25501 cttgacttag aagcattggc agagaaacga gcaacgaatt cttgcaattg tttaattttt
    25561 tcttctgctt tagcattacg gtctgctagc aatttagcag caagctcaga agattccttc
    25621 cagaagtcgt agtttccgac atagagtttg atttttccaa agtcaaggtc ggccatgtga
    25681 gtacaaactt tgtttaagaa gtgacggtcg tgggatacta cgataactgt gttatcaaag
    25741 tcaatcaaga agtcttctaa ccaagtaatc gattggatat ccaaaccgtt agtaggctcg
    25801 tccaagagaa gaacatctgg tttaccaaaa agtgctttgg cgaggagaac ctttactttt
    25861 tcaccgttgg ccaattcgct catgttttgg tagtgtaatt cttctggaat gtttaggttt
    25921 tgaagtagtt gagaggcttc actctctgct tcccaacctc caagttcggc aaactctcct
    25981 tcgagttcgg cagcacgaac cccgtcctcg tctgagaaat cttccttcat gtagatagca
    26041 tctttctctt tcatgatgct ataaagtttt tcatttccca tgataacgac atcaatggca
    26101 cgttcatctt cgtagtcaaa gtgattttga cgaagaacag agagacgttc atctggacca
    26161 agagagatgt gaccagtagt aggttcgata tctccagcta aaatttttaa aaaggttgat
    26221 tttccggcac cattagcacc gattaatccg taagtatttc cttctgtaaa tttgatattg
    26281 acatcatcaa aaagtttgcg atcactaaaa cgtagtgaaa catcagatac tgtaagcaat
    26341 atttttctcc tatatgtgta atatatttat tctactagaa aatacagaaa tattcaaatt
    26401 tttatttgtc aattttgtgt aaattatatt tacagtatcc tttacacaaa tctgtaaaaa
    26461 gcaaggctga tttattttga taaattacgg ttatttcatt aaaaaaatgc tataattgaa
    26521 aggactatat cgaaggagaa caaaatgact aaacccatta ttttaacagg agaccgtcca
    26581 acaggaaaat tgcatattgg acattatgtt ggaagtctca aaaatcgagt attattacag
    26641 gaagaggata agtatgatat gtttgtgttc ttggctgacc aacaagcctt gacagatcat
    26701 gccaaagatc ctcaaaccat tgtagagtct atcggaaatg tggctttgga ttatcttgca
    26761 gttggattgg atccaaataa gtcaactatt tttattcaaa gccagattcc agagttggct
    26821 gagttgtcta tgtattatat gaatctagtt tcgttagcac gtttggagcg aaatccaaca
    26881 gtcaagacag agatttctca gaaaggattt ggagaaagca ttccgacagg attcttggtc
    26941 tatccaatcg ctcaagcagc tgatatcaca gctttcaagg ctaattatgt tcctgttggg
    27001 acagatcaga aaccaatgat tgagcaaact cgtgaaattg ttcgttcttt taacaatgca
    27061 tataactgtg atgtcttggt agagccggaa ggtatttatc cagaaaatga gagagcaggg
    27121 cgtttgcctg gtttagatgg aaatgctaaa atgtctaaat cactaaataa tggtatttat
    27181 ttagctgatg atgcggatac tttgcgtaaa aaagtaatga gtatgtatac agatccagat
    27241 catatccgcg ttgaggatcc aggtaagatt gagggaaata tggttttcca ttatctagat
    27301 gtttttggtc gtccagaaga tgctcaagaa attgctgata tgaaagaacg ttatcaacga
    27361 ggtggtcttg gtgatgtgaa gaccaagcgt tatctacttg aaatattaga acgtgaactg
    27421 ggtcctattc gtgagcgccg tattgaattt gctaaggata tgggagaagt ttataatatg
    27481 attcaaaaag gtagtgaaag agcgcgtgaa gttgcgggtc aaaccctatc tgaggtaaaa
    27541 ggggcaatgg gacttcatta ctttaactaa gtttatttta caagaaacta tcatttctat
    27601 ctcgaagaaa agatagtttt ttatttaccc ctgtaacatt tgacaaattt ttatagaatg
    27661 gtatgataga tacaatataa aaagagtcaa gctcaaaaag aaagaaaaga ggaaacttcg
    27721 aatgtctaat tgggacacta aatttttgaa aaaaggtttt acctttgatg atgtattgct
    27781 tattccagct gaaagtcatg tgttgcctaa cgatgcagat ttaacaacta aattggcaga
    27841 taatttgact ttaaatatcc caattattac cgctgccatg gacacagtta cagagagtca
    27901 aatggccatt gctattgctc gtgcaggtgg tctcggagtt atccataaaa acatgtcaat
    27961 tgctcaacaa gcagacgagg ttcgtaaggt aaaacgttct gaaaatggag ttattattga
    28021 tccgttcttc ttgacgcctg aacatacaat tgctgaagca gatgagctta tgggtcgtta
    28081 ccgcatcagt ggtgttccag ttgttgaaac acttgaaaat cgtaaattgg ttggtatttt
    28141 gacaaaccga gatcttcgtt ttatttcaga ttataatcaa ccaatttcaa accatatgac
    28201 tagtgaaaat cttgttactg ctcctgtggg tacggatctt gcaacggctg agagtattct
    28261 tcaagagcat cgtattgaaa aacttccgtt ggtcgatgaa gaaggcagtc tttctggttt
    28321 gatcactatc aaagatattg aaaaagttat tgagtttcca aatgcggcta aagatgaatt
    28381 tggtcgtctt ctagttgcag gtgcagtagg tgttacttca gatacatttg aacgtgcaga
    28441 ggctcttttt gaggcaggag cggatgcgat tgttattgat actgcacatg gtcattctgc
    28501 aggtgtcttg cgtaaaattg ccgagattcg tgctcatttc ccagatcgga ctttgattgc
    28561 tggaaatatt gctactgctg aaggtgcacg tgccctttat gaagcgggtg tagacgttgt
    28621 taaggttggt attggaccag gttctatctg tactactcgt gtgattgctg gtgttggtgt
    28681 tccgcaagta acagctatct acgatgctgc agctgttgcg cgcgaatatg gtaaaacgat
    28741 tattgctgac ggtgggatca agtattctgg agatattgta aaagcacttg ctgcaggtgg
    28801 aaatgctgtt atgcttggat ctatgtttgc tggaactgat gaagctccag gcgaaactga
    28861 aatcttccaa ggacgtaaat tcaagactta ccgtggtatg ggatcaattg ctgctatgaa
    28921 gaaaggttca agcgaccgtt atttccaagg ttctgtcaat gaagcaaaca agctcgttcc
    28981 agaaggaatt gaaggtcgtg ttgcttataa aggagcggca gctgatattg ttttccaaat
    29041 gattggtggt attcgctctg gtatgggtta ctgtggtgca gctaacctta aagaactaca
    29101 cgataatgct caatttattg aaatgtctgg tgctggtttg aaagaaagcc atcctcatga
    29161 tgtgcaaatt actaatgagg caccaaatta ttctatgtaa aaaacaatga aaagaactcc
    29221 agtgaaaaca ggagttcttt tacaatgttg tcaatttcca tttacagaag ctttaccatc
    29281 ctgaatagtg aagatactta gattttctgg cagattttga agatggtcta agcttgttgt
    29341 tgtgataaag gtttggattg attgagaaat cgtttctaat aattttaact gtctagtgtt
    29401 gtcaagttca ctcatcacat cgtcaagcag taatatagga gattctgtgg taatgctttc
    29461 cattaattcg atttctgcta attttatcga gaggacgaga ctacgatgtt gaccttggct
    29521 tccgaaacta gcatccatcc catttatata aaaagaaatg tcatctcgat gaggaccgac
    29581 accagtattc tttttaaata aatctctgga tctacttttt tctaaagcaa ttttgaaaga
    29641 ttcggataag ttttgtttgt cagttatatt gacagaagat tgataggata ttgacaactc
    29701 ttcgatctga ttagagagtt caaaatgttt cttacgccca aatgattcta gtttttttat
    29761 gaaatctaag cggtgattca ttacacgaca tccataatca actagctgat catctaacac
    29821 agaaaggaat gtttcatcta ttttttgagc tgattttagg taagtgtttc tttgctttag
    29881 gatgtggtta taattggtta agtcagataa atagattggc ttaatttgcc caagttccat
    29941 atcaatgaat tttcgtcgaa tcgaaggtgc tcctttaatt agttgtaaat cttcaggagc
    30001 aaataagaca acattcatgt gtcctacata atctgaaagg cgtgcctgtt ttaagtgatt
    30061 aacttttgtt acacggcctt tttgtgttag ttcgatttct aggggaatgg atccagtttt
    30121 tttctgaacg agacctgaaa gatgaagttg ttcctcatca aaatgaatga gatttttatc
    30181 tgttcgagtt cgatgactac gcgttaaggc taaaaaatag atagcctcta acatgtttgt
    30241 ttttccttgt gcattacgtc ccaaaaagac attcaattta ggattaaagt ctattttcgt
    30301 ttctttgtaa ttacgaaaag tcttgagaga tagatgttgt agccacatga ttatctacca
    30361 gggaatcgtg gagcttgttg gcttttaggt gatgaagcag gtttcgattt gtctttttta
    30421 actcccttat tcatcttttt gacaagttta gcgatccgtt ctttttcaac tttatcagct
    30481 tggtattcat cttgttcttc agaagtaggt tgtgtcaaca agatgtcaat gttcatgtca
    30541 gggatgtcaa ctttatcgcc aatacgaagt ttttttccac gacgactctc taattcccta
    30601 ttaaagtaaa cagaatgttc agagagaaat gatttaatag ctcctccgct atgtgtaatt
    30661 ccaagttctt tgagtagtgc ttggagggta ataaattctt caaataattt gtattccata
    30721 attcacctca atctttggta ttataccata ttttcctaaa aatagtgaga gagacagcga
    30781 gaaatgtaag cgatttttat ttcaaaagtg ttacagggaa caagaaaatt tcaggttttc
    30841 gtgatataat agaagtctgt atataaggag gtaaatcatg gagttagtgc atggaatttc
    30901 aacacatttt atccaatcaa aaaagtttaa aacaaacaaa attaccgtgc gttttaccgc
    30961 tccattatcc cttgatacga ttgcaggtca catgttgagt gcaagtatgc tagagactgc
    31021 taatcagatg taccccactt ctcaagattt gaggagacac ttggccagtc tatacggtac
    31081 agatatgtca accaattgtt tcagaagagg gcaaagccac attatagaat tgacatttac
    31141 ctatgttcgt gatgagtttt taagtaggaa aaacgtgcta acctctcaga ttttggaact
    31201 tgtaaaagaa actctttttt cacccgcagt agttgataat gggtttgatc cggccttatt
    31261 tgaaattgag aaaaaacaat tgctagcaag tttagcagct gatatggatg attcttttta
    31321 ttttgcacat aaagaattgg ataaattgtt ttttcatgat gaacgtcttc aattggaata
    31381 tagtgattta cgaaatcgta ttttagctga aactccacaa agttcttatt cttgtttcca
    31441 agaattttta gccaatgatc gaatagattt ctttttccta ggtgatttta atgaggttga
    31501 aattcaaaat gtattagaat catttggctt taaaggtcga aaaggagatg tgaaggttca
    31561 gtattgtcaa ccttattcta atatccttca ggaaggtatg gttcggaaaa atgtgggaca
    31621 atccattttg gaattaggtt atcattaccg ttctaaatat ggtgatgagc aacatttacc
    31681 catgattgta atgaatggtt tacttggtgg atttgctcac tctaagctct ttacaaatgt
    31741 ccgtgaaaat gctggattag cttataccat ttcaagtgag cttgatttat ttagtggatt
    31801 cttgaggatg tatgctggta tcaatcgaga aaatcgtaac caggctcgta aaatgatgaa
    31861 taatcaactg cttgatttaa aaaaaggtta ttttacagag tttgagttaa atcagaccaa
    31921 ggaaatgatt cgttggtcgt tgttactttc tcaagataat caatcttcat tgattgaacg
    31981 tgcttatcaa aatgccttat ttggaaaatc ttcagcagac tttaaaagtt ggattgcaga
    32041 gcttgaacaa attgacaaag atgctatttg tagagtagct aataatgtga aactacaagc
    32101 gatttacttt atggaaggaa tagaatgaca aaggttgttt ttgaagaaaa atactatcca
    32161 gctgtaaaag aaaaggttta tcgaactcgt ttggccaacg gattgacagt tgctcttttg
    32221 cctaaaaagg aatttaaaga ggtttacggg agtgtcactg tacagtttgg ttcggtagat
    32281 acgtttgtca cagaagttga cggatatgta aaacaatatc ctggaggaat tgctcatttt
    32341 cttgaacata aattatttga gagagaagat tctagtgatt tgatgtcggc ttttacgagt
    32401 ctaggtgcag atagtaatgc ctttacaagc tttacaaaaa caaactatct tttttcagca
    32461 acggattatt ttttagaaaa tttagattta cttgatgaat tggtaacatc agcacacttt
    32521 actgaagctt ccattctgac agagcaggat attattcagc aagaacgaga aatgtaccaa
    32581 gatgatccag attcgtgttt attcttttca actttagcga atttgtatcc tggtacacct
    32641 ttagcaactg atatagttgg aagtgaggag tccatttccc aaatcaatct aactaatttg
    32701 caagaaaatt ttacaaagtt ttacaaacct gtaaacatgt ctctgttttt agttggtaat
    32761 tttgatgtgg agcgagtaca ggactatttt gaaagcaaag aactgaaaga ttcagatttt
    32821 caggaagtag caagagaaaa gttgttttta cagcctgtaa agccaacaga tagtatgaga
    32881 atggaagtat cttctcccaa actagcgatt ggagttagag gtaagcgaga agtttctgaa
    32941 gcggattgct atcgacatca tattttatta aaattattgt ttgcaatgat gtttggttgg
    33001 acttcggatc gttttcaaaa atgttatgaa tcaggtaaaa ttgatgcgtc cttatctctg
    33061 gaagttgaaa taacaagtcg ctttcatttt gtcatgttga caatagatac gaaagagcca
    33121 gttgctttgt ctcatcaatt taggaaggct attcgtaatt ttacaaagga tttagatatt
    33181 acagaggaac atttagatat tatcaaaaga gagatgtttg gcgaattttt cagtagcatg
    33241 aactctcttg aatttattgc aacgcaatat gatgcttttg aaaatggtga gacaattttt
    33301 gatttgccga aaattttaca ggaaattact ttagaggatg tccttgatgc tggacatcat
    33361 ttaatagatg atggtgacat agttgatttt acaatattcc catcgtagta acctatcata
    33421 atagacacta gaaagaaggg atgacaagta tgagaaaaaa aacaattgga gaggttttac
    33481 gattagctag aatcaatcag ggattgagtt tagatgaatt gcagaaaaag acagaaatcc
    33541 agttagatat gttggaagca atggaagcag acgatttcga tcaacttcca agtccttttt
    33601 acacgcgttc tttcttgaaa aaatatgcat gggctgttga gttagatgac caaattgttt
    33661 tggatgctta tgattctggg agtatgatta cttatgagga agtagatgtt gatgaagatg
    33721 agttgacagg tcgtagacgt tcaagtaaga aaaagaagaa aaaaacatca tttttacctt
    33781 tattttattt tatccttttt gctttatcga ttttaatttt tgtgacttat tatgtttgga
    33841 actatattca aactcaacca gaggagcctt ctctttctaa ttacagtgtg gttcaatcaa
    33901 caagttcaac tagctctgtt ccccactcct caagtagtag ttcttctagt atagaatcag
    33961 ctataagtgt atcaggcgaa ggaaatcatg tagaaatcgc ttataagaca agtaaggaaa
    34021 cagttaaatt gcaattggca gtttcagatg ttacaagttg ggtcagtgtt tcagaaagcg
    34081 aacttgaggg cggtgtaacc ttatcgccaa agaagaaaag tgcagaagca acagttgcaa
    34141 ctaaaagtcc tgtaacaatt acgttaggtg ttgtaaaagg tgttgatttg acagtagata
    34201 atcagactgt tgatttatcg aaattaacag ctcagactgg acaaatcact gtaaccttta
    34261 ctaaaaatta aggaaaaacg aatgaaaaaa gaacaaattc ccaatctctt aacaataggt
    34321 cgaattctct ttatacctat ttttatcttt attttaacga taggaaattc gatagagagt
    34381 catatagttg cagctattat ctttgctgtt gccagtatta ccgactattt agatggatat
    34441 ttagctcgta aatggaatgt ggtcagtaat tttggtaaat ttgcagatcc tatggcggat
    34501 aagttactag ttatgtcggc ttttattatg ttgattgagt taggtatggc tccggcttgg
    34561 attgttgcag tgattatctg tcgtgagtta gctgtgacag gtttaaggct tttattggtt
    34621 gaaactggtg gaacaatttt agcagcagca atgcctggaa aaattaaaac ttttagtcag
    34681 atgtttgcta ttattttctt gctattacat tggactttgc ttggtcaagt tctactttat
    34741 gtagccttat ttttcactat ctactctggc tatgactatt tcaagggtag tgcctatgta
    34801 tttaaaggga catttggttc gaaatgaaat caataattga tgtaaaaaat ctttcttttc
    34861 gctataaaga aaatcagaac tactacgatg tgaaggatat tacgtttcac gtgaaacgtg
    34921 gagaatggct ttcgattgta gggcataatg gtagtggtaa atcaacgacg gttcgattaa
    34981 ttgatggctt actggaagca gaatccggag agattgtaat tgatggccaa cgtttgactg
    35041 aggaaaatgt ttggaatata cgtcgtcaaa tcggtatggt ttttcaaaat ccagacaatc
    35101 aatttgttgg agcgactgtt gaagatgatg ttgcttttgg tttggaaaat cagggacttt
    35161 ctcgtcaaga aatgaaaaag agagtggaag aagctctggc tttagttggc atgttggact
    35221 ttaaaaagag agagccagcg cgtctatcag gtggccaaaa gcaacgtgtg gccattgcag
    35281 gtgttgtagc cctaagacca gctattttaa tcttagatga agcaacgagt atgttggatc
    35341 ctgaggggcg tagagaactt attgggacag taaaaggaat tcgaaaagac tatgatatga
    35401 cggtcatttc tattacccat gatttggaag aagtcgccat gagtgatcgc gtattggtca
    35461 tgaaaaaagg ggaaattgaa tcaactagta gtccaaggga gcttttctct cgaaatgatt
    35521 tagatcaaat tggattagac gatccttttg ctaatcaatt aaaaaaatct ttgagccaga
    35581 atggctatga tttacctgaa aattatttga cagaaagtga gctagaggat aagctatggg
    35641 aattgctcta gaaaatgtga attttatata tcaagaaggt actcccttag cttcagcagc
    35701 tttgtcggat gtttctttga cgattgaaga tggctcttat acagctttaa ttgggcacac
    35761 aggtagtggt aaatcaacta ttttacaact cttaaatggt ttattggtgc caagtcaagg
    35821 gagtgtgagg gtttttgata ccttaatcac ctcgacttct aaaaataaag atattcgtca
    35881 aattagaaaa caggttggct tggtatttca gtttgctgaa aatcagattt ttgaagaaac
    35941 ggttttgaag gacgttgctt ttggaccgca aaattttgga gtttctgaag aagatgctgt
    36001 gaagactgcg cgtgagaaac tggctctggt tggaattgat gaatcacttt ttgatcgtag
    36061 tccgtttgag ctgtcagggg gacaaatgag acgtgttgcc attgcaggca tacttgccat
    36121 ggagccatct atattagtct tagatgagcc aacagctggt ctagatcctc tagggagaaa
    36181 agagttgatg accctgttca aaaaactcca ccagtcaggg atgaccatcg tcttggtaac
    36241 gcatttgatg gatgatgttg ctgaatatgc taatcaagtc tatgtaatgg aaaagggacg
    36301 tttagtaaag gggggcaaac caagtgatgt ctttcaagac gttgttttta tggaagaagt
    36361 tcagttggga gtacctaaaa ttacggcctt ttgtaaacga ttggctgata gaggcgtgtc
    36421 atttaaacga ttaccgatta agatagagga gttcaaggag tcgctaaatg gatagtatga
    36481 ttttggggcg ttatatccca ggggattcga ttgttcaccg attggatcca cgtagcaaat
    36541 tgcttgctat gatgctactg attttgattg tgttttgggc taataacccc ttgacgaatc
    36601 tgattctttt tatagcgaca gggatattta ttgccttgtc aggagtatct ctttcatttt
    36661 ttattcaggg cttgaagtct atgtttttct tgattgcctt cacaactatt tttcaactat
    36721 ttttcatttc taatgggaat gttttatttg agttttcgtt tgtgagaatc acggattatg
    36781 ctttgcaaca agctgggatt attttttgtc gctttgtatt gattattttc ttttcaactt
    36841 tgttaacctt aacaaccatg cctttaagtt tggcatcagc tgtcgaagct ttattagcac
    36901 ctttaaagcg tgtgaaagtt ccagttcatg aaattggatt gatgctgtct atgagtttgc
    36961 gttttgtccc aaccttgatg gatgatacga ctcggattat gaatgcacag aaagctcgtg
    37021 gagtggattt tggagaagga agcatcgttc aaaaagtaaa ggcgatgatt cccattttga
    37081 ttcctctttt tgcgacaagt ttaaaacgtg cagattcctt ggctatcgct atggaagcgc
    37141 gtggctatca gggtggaaaa ggcagaagtc aataccgaca attgaaatgg actctaaagg
    37201 atacgctgac cattcttgtt attctcgtac ttggttgttg tttatttttc ttaaaatctt
    37261 agtagctttc aggaattgat aaaaagttac tgtaacagtt tttgatataa aggtagggat
    37321 atgaaccgtt ttaaaaaatc aaaatatgtc attattgttt ttgtcactgt tctgcttgtg
    37381 tcagctctct tagcgacgac ttattcaagt acaattgtga caaaattagg agatggaatc
    37441 tcattggttg atagagttgt acaaaaacct tttcagtggt ttgattctgt caaatcagat
    37501 ttggctcatt tgacacgaac atataatgaa aatgaaagtt tgaagaaaca gctttaccaa
    37561 ttagaagtta aatcaaatga ggtggaaagt ttaaagacag aaaatgaaca actgcgccaa
    37621 ttgcttgata tgaagtctaa attgcaagcc acaaagactt tagcagcaga tgttattatg
    37681 cgttctccgg tatcttggaa gcaggagttg accttagatg caggtagatc aaaaggtgct
    37741 tctgagaaca tgttagctat tgcaaatggt ggcttgattg ggagtgtttc aaaagtagag
    37801 gagaactcta ctatagtcaa ccttctgaca aatacggaaa atgctgataa gatttctgtt
    37861 aaaattcaac atggctctac tacaatttat ggaattatta ttggctatga caaggaaaat
    37921 gacgttctta aaattagcca attaaatagt aatagcgata ttagtgcggg agataaggtg
    37981 actactggtg gattaggaaa ctttaacgtt gctgatattc ctgttggtga agtggttgcc
    38041 acaacgcata gtacagacta tttgacacga gaagtaactg ttaaattgag tgcagatact
    38101 cataatgtag atgtgataga attagtgggg aattcataat gagacagttg aagcgagttg
    38161 gagtattttt attgcttcct ttctttgttc taattgacgc ccatattagc cagcttctgg
    38221 gctcattttt cccccatgta catttggcta gtcattttct ttttctattt ctcttatttg
    38281 agacgataga agtatcagag tatctctacc tagtctattg ttttgttata ggcttggttt
    38341 atgatgttta ctttttccat ctaataggga ttacaactct cttatttatc ttattgggag
    38401 ccttccttca taaattgaat agtgttattt tgttgaatcg ttggacaaga atgctagcta
    38461 tgattgtgct gacattcctg tttgaaatgg gtagttatct tttggctttt atggtagggt
    38521 tgacagtaga tagcatgtcg atttttatag tctatagctt ggtaccgacg atgattttaa
    38581 attttttatg gattactgtt tttcaattta tttttgaaaa atattatcta taagaacgac
    38641 atataaatgt aacaaaggcg taatatttat taggcctttt tttggtatac tagtattgtc
    38701 tttaaaagaa ggagtatcta cgtaatatga agaaaaaaat cttagcgtca cttttattaa
    38761 gtacagtaat ggtttctcaa gtagctgttt taacaactgc gcatgcagaa acgactgatg
    38821 acaaaattgc tgctcaagat aataaaatta gtaacttaac agcacaacaa caagaagccc
    38881 aaaaacaagt tgaccaaatt caggagcaag tatcagctat tcaagctgag cagtctaact
    38941 tgcaagctga aaatgataga ttacaagcag aatctaagaa actcgagggt gagattacag
    39001 aactttctaa aaacattgtt tctcgtaacc aatcgttgga aaaacaagct cgtagtgctc
    39061 aaacaaatgg agccgtaact agctatatca ataccattgt aaactcaaaa tcaattacag
    39121 aagctatttc acgtgttgct gcaatgagtg aaatcgtatc tgcaaacaac aaaatgttag
    39181 aacaacaaaa ggcagataaa aaagctattt ctgaaaaaca agtagcaaat aatgatgcta
    39241 tcaatactgt aattgctaat caacaaaaat tggctgatga tgctcaagca ttgactacga
    39301 aacaggcaga actaaaagct gctgaattaa gtcttgctgc tgagaaagcg acagctgaag
    39361 gggaaaaagc aagtctatta gagcaaaaag cagcagctga ggcagaggct cgtgcagctg
    39421 cggtagcaga agcagcttat aaagaaaaac gagctagcca acaacaatca gtacttgctt
    39481 cagcaaacac taacttaaca gctcaagtgc aagcagtatc tgaatctgca gcagcacctg
    39541 tccgtgcaaa agttcgtcca acatacagta caaacgcttc aagttatcca attggagaat
    39601 gtacatgggg agtaaaaaca ttggcacctt gggctggaga ctactggggt aatggagcac
    39661 agtgggctac aagtgcagca gcagcaggtt tccgtacagg ttcaacacct caagttggag
    39721 caattgcatg ttggaatgat ggtggatatg gtcacgtagc ggttgttaca gctgttgaat
    39781 caacaacacg tatccaagta tcagaatcaa attatgcagg taatcgtaca attggaaatc
    39841 accgtggatg gttcaatcca acaacaactt ctgaaggttt tgttacatat atttatgcag
    39901 attaatttac agagggactc gaatagagcc ctcttttcag gttttaccgt gacaatccct
    39961 attaaaaatt atatcaaaat agcttgaaaa tattggaaaa gtatggtaga atgaaaattg
    40021 tcgtgtgaac gataatactc attcttgatg aattgtgaag cagttgccct tgggtcgttt
    40081 tgcgagttga agtcaagaag aggaaaaaaa caaaaaggag aaatactcat ggcagtaatt
    40141 tcaatgaaac aacttcttga ggctggtgta cactttggtc accaaactcg tcgctggaat
    40201 cctaagatgg ctaagtacat ctttactgaa cgtaacggaa tccacgttat cgacttgcaa
    40261 caaactgtaa aatacgctga ccaagcatac gacttcatgc gtgatgcagc agctaacgat
    40321 gcagttgtat tgttcgttgg tactaagaaa caagcagctg atgcagttgc tgaagaagca
    40381 gtacgttcag gtcaatactt catcaaccac cgttggttgg gtggaactct tacaaactgg
    40441 ggaacaatcc aaaaacgtat cgctcgtttg aaagaaatta aacgtatgga agaagatgga
    40501 actttcgaag ttcttcctaa gaaagaagtt gcacttctta acaaacaacg tgcgcgtctt
    40561 gaaaaattct tgggcggtat cgaagatatg cctcgtatcc cagatgtgat gtacgtagtt
    40621 gacccacata aagagcaaat cgctgttaaa gaagctaaaa aattgggaat cccagttgta
    40681 gcgatggttg acaccaatac tgatccagat gatatcgatg taatcatccc agctaacgat
    40741 gacgctatcc gtgctgttaa attgatcaca gctaaattgg ctgacgctat tatcgaagga
    40801 cgtcaaggtg aggatgcagt agcagttgaa gcagaatttg cagcttcaga aactcaagca
    40861 gattcaattg aagaaatcgt tgaagttgta gaaggtgaca acgcttaatt tatacaaata
    40921 gtaattacct aggagggcgg ggcttagccc ggctctccta ttttcaaaaa atataggaga
    40981 attaaaatgg cagaaattac agctaaactt gtaaaagagt tgcgtgaaaa atctggtgcc
    41041 ggtgttatgg acgctaaaaa agcgcttgta gaaacagacg gtgacatcga aaaagcgatt
    41101 gaattgcttc gtgaaaaagg tatggctaag gcagctaaga aagctgaccg tgttgctgca
    41161 gaaggtttga ctggtgttta tgttaacggt aatgttgcag cagttattga agtaaacgct
    41221 gaaactgact tcgttgcaaa aaacgctcaa ttcgttgaat tggtaaatac tacagctaaa
    41281 gtcattgctg aaggaaaacc tgctaataat gaagaagctc ttgctttgat aatgccttca
    41341 ggtgaaactc ttgaagctgc atacgtatct gcaacagcaa ctatcggaga gaaaatctca
    41401 ttccgtcgct ttgcattgat tgaaaaaaca gacgcacaac actttggagc ataccaacat
    41461 aacggtggac gtatcggtgt tatttcagtt gttgaaggtg gagacgaagc acttgctaaa
    41521 caattgtcaa tgcacatcgc agcgatgaaa ccaacagttc tttcttacaa agaattggat
    41581 gagcaattcg ttaaagatga gttggcacaa ttgaatcacg ttatcgacca agacaacgaa
    41641 agccgtgcaa tggttaataa accagctctt ccacacttga agtatggatc aaaagctcaa
    41701 ttaactgatg atgttattgc tcaagctgaa gctgacatca aagctgaatt ggctgcagaa
    41761 ggcaaaccag aaaaaatctg ggacaaaatt atcccaggta aaatggatcg cttcatgctt
    41821 gataatacta aagttgacca agcttacaca cttcttgcac aagtttacat catggatgac
    41881 agcaagacag ttgaagcata ccttgaatca gttaacgctt cggtagttga gtttgctcgc
    41941 tttgaagttg gtgaaggtat cgagaaagct gcaaacgact tcgaagctga agttgcagct
    42001 acaatggcag cagccttgaa taactaataa tagaaaggaa gcaatttgct tccttttttg
    42061 tatagggctt atatttttcc tgaaattgtt tttcccccag tctcactcga ttagaataat
    42121 taaaacaaaa agccctataa taagggctaa gtgcatttag gagactatac ttcaaattca
    42181 tagtaagcgc gtcataacaa ggtatctatc ctaattcccc aacttccagt atactagata
    42241 aaaaataatt atcggaggaa aggtattgta ctatgatgat tcaactaagt gatttaggtc
    42301 aagttcacat tgtttgtggc aagacagata tgaggcaggg aatagactca ttagcctatg
    42361 tagttaaaac ccactttgaa ttggattctt tctccggtca agtctttctc ttttgtggtg
    42421 gacgtaaaga ccgctttaaa gtcctttact gggatggtca aggattttgg ctactatata
    42481 aacgctttga gaacggaaaa ctgacttggc taagtacaga aaaggatgtc aaagctctcg
    42541 cacctgaaca agtagactag cttatgaagg gcttttctat cactccaaaa atatagtaga
    42601 ttgaaactag aatagtacac ctctgcttct aaaacattgt tagaaatcga tttgactgtc
    42661 ctgatcgatt tgtcctgttc ttatttcatt ttactataaa tccatcagaa agtcgtgatt
    42721 tctattgaaa tgaggacttt ctttttacac tcatctgctt tcaaaaagca ttctagtccg
    42781 tctccgatta acgatggact ttatcacctc cttctctagt ccttgtatga catcttccaa
    42841 agttcgaaag gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat
    42901 gggttcatct ctggtgtgta tggaggaata aaggtaaaac caatattagt cggaatcttt
    42961 aaggtacttg atttatgcca tatagcattg tccataacga gtaaaaaata atcatctgga
    43021 tgctcctatt cctaaagccc ctttagcgca tagctttggc tcagcttcta ttatcgctca
    43081 catcatccat cagaagttta atctgaaggt acccaattat cgccaagaag aagattgggc
    43141 taggatgggt ttaccaatca cacgtaagga aatctctaat cggcatatca agacgagtca
    43201 atactatttg gagccccttt ataacctctt gcgagagaga ctattgactc agcccttact
    43261 tcatgcggat gaaacttctt atagggtgct agagagtgat agtcagctga cttactattg
    43321 gacttttttg tctgggaaag ctgagaaaca agggattacg ctttaccatc atgtcctaat
    43381 cgatttgttc atatcttatt tcaatccatt ataaatagtg agaaatatct atcctatctt
    43441 ctagaatgtc ttccaaacgt ggaaactctc gtaaacaaag aggttttaga ggcctattta
    43501 ccatggacta aagttgtaca agaaaagtgc aaataagaaa tctccagatt aggaactatc
    43561 cgtgagttct ctagtctgga gatttttcaa tagacttcgt tattggacgg ttacaattca
    43621 taaagtgctg tagagagata acgttcaccg ttatctggtg ctagggcaag gactttttta
    43681 cctgtaccta attttttggc aacctcgatg gctccgtaga tagctgcagc tgaggaaatc
    43741 cctacaagga agccttcttt tccaccaatt tcacgtccga gtgcaagagc gtcatctgat
    43801 gttacacgaa cgataccatc ataggcttta gtatcaagtg tatcaggaat aaatccagct
    43861 gagatacctt gaattttgtg aggaccaggt ttttcaccag atagaatagc agattcatct
    43921 gcttctactg caaaaacttg aatgttagaa ttttctgatt tgagtgcatg agaaacacca
    43981 gaaatcgttc caccagtacc tactccagca acaaaggcat ctaatccatc tttaccgaaa
    44041 gcagctagta tctcagctcc tgttgttctt tcgtgtactt ctggattagc tggattgtca
    44101 aattgaagag gaaggaaacc atcacgttca gcagcgattt cttgagcctt agcaatagca
    44161 cctttcattc cctcgctacc aggagttagg acgagttcag caccataagc ttggataatt
    44221 ttacgtcgtt ctacactcat agtttcaggc ataacgatga cgactttata ccctttagca
    44281 gcacctaccc atgaaagtcc aataccggtg tttccacttg ttgcttcaac aatagtagaa
    44341 ccaagtttca gaataccatc ttgttcagct ttttcaatca tgctaagggc aatacggtct
    44401 tttacagatg aaccaggatt aaatgcttca agctttatat agacgtctgc agcaccttct
    44461 ggcacgatgt tgttaagttt aacaatcggt gtttgaccga ttaattcagt aatgttgtta
    44521 taaatagaca tatgaatacc tctttgtata agatatcttt agtataacgc tatccatacc
    44581 atttgtaaaa tatagaaatc ctatcgaagc gataggattt ctatatatca tagatcaaag
    44641 tcattaattt tcaagtgatt gcgttcagtt aattctagta aataggtgtg aaggaaaacg
    44701 atatcaggtt tcgtttgaat tgcttcattt tctagtatat tttggtacgc atctttttat
    44761 tttgctcgct aaagtagttg tgagaatgtc aacgaaacgc tgtattattc attgtttaca
    44821 ctaagtttac aggaacttca acctctcgta aaccttggtc agttaaagtg acttttccat
    44881 taaaaaactc cacaagtgca gctttaatag tttctttttc ttctttatca acataaatca
    44941 tcgtatcgac ttgatctgta aagtttgtat ccagctccat gagatcatgt tctttaagga
    45001 agttactgta ctcttggtac tgagcataag acatttgaat agcaatgcca gcctgttctt
    45061 ttatttcaat aataccaatt tctttgacag ctaaggcgac actgccggcg taagcacgaa
    45121 ttagtcctcc agcgcctagt ttaataccac caaagtagcg tgtcacgacc acacagacat
    45181 tggtgagatt gtgattttct agtaccccaa gcatgggaac accagcagta ccactaggct
    45241 caccatcatc acttgtacgt ttaatttcac tacgttctcc aataataaag gcagagcagt
    45301 tatgtgtcgc tttgtagtgt tcttttttga tggcagtaat gaagtcacga gcctcttctt
    45361 cgctataaac acgcttggca tggcagataa agcgagattt tttgatttct tcttggactt
    45421 ggccgtcctc tttaattgtc ctaaattcca tgatttaatt gtactaaaaa atcatctaaa
    45481 gtgctagttt ttacgaataa agaagtatga aagtaaattt agattatctc ggtcgtttat
    45541 ttactgagaa tgaattaaca gaagaagaac gtcagttggc ggagaaactt ccagcaatga
    45601 gaaaggagaa ggggaaactt ttctgtcaac gttgtaatag tactattcta gaagaatggt
    45661 atttgcccat cggtgcttac tattgtcgag agtgcttgct gatgaagcga gtcagaagtg
    45721 atcaaacttt atactatttt ccgcaggagg attttccgaa gcaagatgtt ctcaaatggc
    45781 gcggccaatt aactcctttt caagagaagg tgtcagaggg actgcttcaa gcagtagaca
    45841 agcaaaagcc aaccttagtt catgcggtaa caggagctgg aaagacagaa atgatttatc
    45901 aagtagtggc taaagtgatc aatgcgggtg gtgcagtgtg tttggctagt cctcgcatag
    45961 atgtttgttt ggagctgtac aagcgcctgc aacaggattt ttcttgcgga atagctttgc
    46021 tacatggaga atcggaacct tattttcgaa caccactagt tgttgcaaca acccatcagt
    46081 tattgaagtt ttatcaagct tttgatttgc tgatagtgga tgaagtagat gcttttcctt
    46141 atgttgataa tcccatgctt taccacgctg tcaagaatag tgtaaaggag aatggattga
    46201 gaatcttttt aacagcgact tcgaccaatg agttagataa aaaggtccgt ttaggagaac
    46261 taaaaagact gaatttaccg agacggtttc atggaaatcc gttgattatt ccaaaaccaa
    46321 tttggttatc ggattttaat cgctacttag acaagaatcg tttgtcacca aagttaaagt
    46381 cctatattga gaagcagaga aagacagctt atccgttact catttttgct tcagaaatta
    46441 agaaagggga gcagttagca gaaatcttac aggagcaatt tccaaatgag aaaattggct
    46501 ttgtatcttc tgtaacagag gatcgattag agcaagtaca agcttttcga gatggagaac
    46561 tgacaatact tatcagtacg acaatcttgg agcgtggagt taccttccct tgtgtggatg
    46621 ttttcgtagt agaggccaat catcgtttgt ttaccaagtc tagtttgatt cagattggtg
    46681 gacgagttgg acgaagcatg gatagaccga caggagattt gcttttcttc catgatgggt
    46741 taaatgcttc aatcaagaag gcgattaagg aaattcagat gatgaataag gaggctggtc
    46801 tatgaagtgc ttgttatgtg ggcagactat gaagactgtt ttaactttta gtagtctctt
    46861 acttctgagg aatgatgact cttgtctttg ttcagactgt gattctactt ttgaaagaat
    46921 tggggaagag aactgtccaa attgtatgaa aacagagttg tcaacaaagt gtcaagattg
    46981 tcaactttgg tgtaaagaag gagttggagt cagtcataga gcgattttta cttacaatca
    47041 agctatgaag gattttttca gtcggtataa gtttgatgga gacttcctgt taagaaaagt
    47101 tttcgcttca tttttaagtg aggagttgaa aaagtacaaa gagtatcaat ttgttgtaat
    47161 tcccctaagt cctgatagat atgctaatag aggatttaat caggttgagg gcttggtaga
    47221 ggcagcaggc tttgagtatc tagatttatt agagaaaaga gaagagagag ccagttcttc
    47281 taaaaatcgt tcagagcgct tggggacaga acttcctttc tttattaaaa gtggagtcac
    47341 tattcctaaa aaaatcctac ttatagatga tatctatact acaggagcaa ctataaatcg
    47401 tgttaagaaa ctgttggaag aagccggtgc taaggatgta aaaacatttt cccttgtaag
    47461 atgaggaaaa aatttgcaaa aatagaatga aagcgttata ataaaatcat aaaaacaaaa
    47521 atgtttagaa agaaggtact catatgatta aatatagtat ccgtggtgaa aacctagaag
    47581 taacagaagc aattcgtgat tatgtagttt ctaaactcga aaagatcgaa aagtacttcc
    47641 aaccagaaca agagttggat gcccgaatta acttaaaagt ttatcgtgaa aaaacggcta
    47701 aagtggaagt aacgattccg cttggatcta ttactctccg cgcagaagat gtatctcaag
    47761 atatgtatgg ttcaattgac cttgtaactg ataaaattga acgtcagatt cgtaaaaata
    47821 aaacaaaaat cgagcgtaaa aataaaaata aggtagcaac tggtcaatta tttacagatg
    47881 ctttggtgga agattcaaat attgtccagt ctaaagttgt tcgttcaaaa caaattgatt
    47941 taaaaccaat ggatttggaa gaagcaattc tacaaatgga tttattgggg catgatttct
    48001 ttatctatgt ggatgttgaa gatcagacaa ccaatgtgat ttatcgtcgt gaggatggcg
    48061 aaattggttt gttagaggtt aaagaatctt aatttcaata tgtgtaaagg taggtttact
    48121 gaattgtaaa ctaccttttt cttataattg atagaattac tgattacact tttaaaaagt
    48181 cgctttttga ggggtattat ggtataatgg gtgccaagag gttttgaatg aaaaaatttt
    48241 atgtaagtcc aatttttcct attctagtag gattgattgc gtttggagtc ttatccactt
    48301 tcattatttt tgttaataat aatctgttga cggttttaat tttgtttctt tttgtaggag
    48361 gctatgtttt tttatttaag aaactgagag tgcattatac aaggagtgat gtagaacaga
    48421 tacagtatgt aaaccaccaa gcggaagaaa gtttgacagc tctattggaa cagatgcctg
    48481 taggtgttat gaaattgaat ttatcttctg gagaggttga gtggtttaat ccctatgctg
    48541 aattgatttt gaccaaggaa gatggtgatt ttgatttaga agctgttcaa acgattatca
    48601 aggcttcagt aggaaatccg tctacttatg ccaagcttgg tgagaagcgt tatgctgttc
    48661 atatggatgc ttcttccggt gttttgtatt ttgtagatgt atccagggaa caagccataa
    48721 cagatgaatt ggtaacaagt cgaccagtga ttgggattgt ctctgtggat aattatgatg
    48781 atttggagga tgcaacttct gagtcagata ttagtcaaat caatagtttt gtagctaatt
    48841 ttatatcaga gttttcagaa aaatacatga tgttttctcg tcgggtaagt atggatcgat
    48901 tttatctatt tactgactac acggtgcttg agggcttgat gaatgataaa ttttctgtta
    48961 ttgatgcttt cagagaagag tcgaaacaga gacagttgcc cttgacttta agtatgggat
    49021 tttcttatgg cgatggaaat catgatgaga tagggaaagt tgctttgctc aatttgaact
    49081 tggctgaagt acgtggtggc gaccaggtgg ttgttaagga aaacgacgaa acgaaaaatc
    49141 cagtttattt tggtggtggg tctgctgctt caatcaagcg tacacggact cgtacgcgcg
    49201 ctatgatgac agctatttca gataagattc ggagtgtaga tcaggttttt gtagtcggtc
    49261 acaaaaattt agacatggat gctttgggct ctgctgtagg tatgcagttg ttcgccagca
    49321 atgtgattga aaatagctat gctctttatg atgaagaaca aatgtctcca gatattgaac
    49381 gagctgtttc attcatagaa aaagaaggag ttacgaagtt gttgtctgtt aaggatgcaa
    49441 tggggatggt gaccaatcgt tctttgttga ttcttgtaga ccattcaaag acagccttaa
    49501 cattatcaaa agaattttat gatttattta cccaaaccat tgttattgac caccatagaa
    49561 gggatcagga ttttccagat aatgcagtca ttacttatat cgaaagtggt gcaagtagtg
    49621 ccagtgagtt ggtaacggaa ttgattcagt tccagaattc taagaaaaat cgtttgagtc
    49681 gtatgcaagc aagtgttttg atggctggta tgatgttgga tactaaaaat ttcacctcgc
    49741 gagtaactag tcggacattt gatgttgcta gctatctcag aacgcgcgga agtgatagta
    49801 ttgctatcca ggaaattgct gcgacagatt ttgaagaata tcgtgaggtt aatgaactta
    49861 ttttacaggg gtgtaaatta ggttcagatg tactaatagc agaggctaag gacacgaaat
    49921 gctatgatac agttgttatt agtaaggcag cagatgccat gttagccatg tcaggtattg
    49981 aagcgagttt tgttcttgcg aagaatacac aaggatttat ctctatctca gctcgaagtc
    50041 gtagtaaact gaatgtacaa cggattatgg aagagttagg cggtggaggc cactttaatt
    50101 tggcagcagc tcaaattaaa gatgtaacct tgtcagaagc aggtgaaaaa ctgacagaaa
    50161 ttgtattaaa tgaaataaag gaaaaggaga aagaagaatg aaagtaatct ttttagcaga
    50221 tgttaaagga aaaggtaaaa aaggcgaaat taaggaagta ccaacagggt atgcgcaaaa
    50281 ctttcttatc aaaaagaatc tagccaaaga agcgactgct caagctgtag gtgaacttcg
    50341 tggtaaacaa aaatcggaag aaaaagctca cgctgagatg attgcagaag gaaaagcaat
    50401 taaagcacaa cttgaagcag aagaaactgt tgtagaattt gttgaaaaag ttggtccaga
    50461 tggtcgtacc tttggttcta ttaccaataa gaagattgca gaagaattgc aaaagcaatt
    50521 tggaattaag attgataaac gtcatattca agtacaagct ccgattcgag cggttggttt
    50581 gattgatgtg ccagtgaaaa tctatcaaga tatcacaagt gtaatcaatc ttcgtgtgaa
    50641 agaaggataa gtttacacct tcttgacaag attgtaaaag gaagggaagt ctgatggcag
    50701 aagtagaaga gttacgagta caacctcaag atatcttagc tgagcaatcc gttttagggg
    50761 ctatctttat tgatgagagt aaacttgttt ttgtgcgaga atacattgag tctcgggact
    50821 tttttaagta tgcccatcgt ttgattttcc aagccatggt cgatttatcc gatcgtggtg
    50881 atgccataga tgcaacaacg gttcgtacta tccttgataa tcaaggtgat ttacagaata
    50941 ttggtggctt gtcttacttg gttgagattg ttaattctgt gccaacttct gctaatgcgg
    51001 agtattatgc taagattgtt gcagaaaaag caatgctacg tcgtttaatt gccaagttga
    51061 cagagtctgt caaccaagct tacgaagcgt cacaaccagc tgatgaaatt attgctcagg
    51121 cagaaaaagg gttgattgat gtcagtgaaa atgcaaatcg aagcgggttt aagaacattc
    51181 gagatgtgtt gaatctcaac tttggaaatc tggaagctcg ctcgcaacaa acgaccgata
    51241 ttacaggtat tgcgacaggt tatcgtgatt tggatcatat gacaacagga cttcatgagg
    51301 aggagttgat tatcttagca gctcgtccag cagttggtaa gacagcattt gccttgaata
    51361 tcgctcagaa tattgggact aagttggaca aaacggttgc tattttttca ctcgaaatgg
    51421 gtgcggaaag cttggtagac cgtatgttag ctgcagaagg cttggtggag tcacattcta
    51481 tccgtacagg gcaattgaca gatgaggagt ggcaaaaata tactattgct cagggtaatc
    51541 tagctaacgc cagtatctat atcgatgata cgccaggtat tcggattaca gagattcgtt
    51601 ctcgttctcg taaattggct caagaaactg gaaatcttgg tttgattttg atagactatt
    51661 tgcaacttat cacgggaact ggtcgagaaa atcgtcaaca agaagtttct gaaatttctc
    51721 gtcagttgaa aatactagcc aaggaattga aggttccagt aatcgctctg agtcagcttt
    51781 ctcgtggtgt agaacaacgt caggacaaga gaccggtctt gtctgatatt cgtgaatctg
    51841 ggtctattga gcaggacgct gatatcgtag cttttctcta tcgcgatgac tactatgaac
    51901 gtggtggtga agaagaggag ggtatcccaa ataataaggt ggaagttatt atcgagaaaa
    51961 accgtagtgg agctcgtgga acagtggaat tgattttcca aaaagaatac aataaatttt
    52021 caagtatctc aaagagggag gcataagatg tcagatgcat ttacagatgt agccaagatg
    52081 aaaaaaatca aagaagaaat caaggcacat gagggacaag tcgtagaaat gactttggag
    52141 aatggtcgta agcgccaaaa aaatagattg ggtaagctaa ttgaagttta tccatcccta
    52201 tttattgtgg agtttgggga tgtggaagga gataaacaag ttaatgttta cgttgaatcc
    52261 tttacttact cagatattct tacagaaaag aatttgattc attatcttga ctaaagtgag
    52321 aaattttctc actttttctt ttttctccga ataatttagg tgaaggcaat catcgcttta
    52381 tattattttt taaggaggaa gaatgaaaat tttaccgttt atagcaagag gaacaagtta
    52441 ttacttgaag atgtcagtta aaaagcttgt tcctttttta gtagtaggat tgatgctagc
    52501 agctggtgat agtgtctatg cctattccag aggaaatgga tcgattgcgc gtggggatga
    52561 ttatcctgct tattataaaa atgggagcca ggagattgat cagtggcgca tgtattctcg
    52621 tcagtgtact tcttttgtag cctttcgttt gagtaatgtc aatggttttg aaattccggc
    52681 agcttatgga aatgcgaatg aatggggaca tcgtgctcgt cgggaaggtt atcgtgtaga
    52741 taatacaccg acgattggtt ccattacttg gtctactgca ggaacttatg gtcatgttgc
    52801 ctgggtgtca aatgtaatgg gagatcagat tgagattgag gaatataact atggttatac
    52861 agaatcctat aataaacgag ttataaaagc aaacacgatg acaggattta ttcattttaa
    52921 agatttggat agtggcagtg ttgggaatag tcaatcctca gcttcaacag gcggaactca
    52981 ttattttaag accaagtctg ctattaaaac tgaaccccta gttagtgcaa ctgtgattga
    53041 ttactattat cctggggaga aggttcatta tgatcagata cttgaaaaag acggctataa
    53101 gtggttgagt tatactgcct ataatggaag ctatcgttat gttcaattgg aggctgtgaa
    53161 taaaaatcct ctaggtaatt ctgttctttc ttcaacagga ggaactcatt attttaagat
    53221 caagtctgct attaaaactg aacccctagt tagtgcaact gtgattgatt actattatcc
    53281 tggagagaag gttcattatg atcagatact tgaaaaagac ggctataagt ggttgagtta
    53341 tacggcttat aacggaagtc gtcgctatat acagctagag ggagtgactt cttcacaaaa
    53401 ttatcagaat caatcaggaa atatctctag ctatggatcc aataatagtt caactgtcgg
    53461 ttggaagaaa ataaatggta gttggtatca tttcaaatca aatggttcta aatcaacagg
    53521 atggctgaaa gacggttcta gctggtatta tttgaaatta tctggtgaaa tgcagacagg
    53581 atggttaaag gagaatggct cgtggtatta tctgggtagt tcaggggcaa tgaaaacagg
    53641 ctggtaccag gtctctggta agtggtatta ttcttactct tcaggcgcct tagctattaa
    53701 tacgacggtg gatggctaca gagtaaacag tgatggagaa cgagtataga aaattggagt
    53761 aggagaaatt tcctgctctt ttctgtaagc agtttccttg acatttttct tattttgcgc
    53821 tatcatatat acatataata tatgggagtc tgtgtacagt ctgagaggaa gtgttaaact
    53881 tcgaccgcac ctgatctggg taatgccagc ggagggaacg atacttagtc taattttgca
    53941 ccttttccat gtatggtaaa ggtttttctt ttttttaaaa ggaaaacgag aagaggaggt
    54001 tcttatgaaa gcaagcattg ccttgcaagt tttaccccta gcacagggga ttgatcggat
    54061 agctgttatt gatcaggtca ttgcttatct gcaaactcaa gaagtgacga tggtagtgac
    54121 accatttgaa acggtcttgg aaggggagtt tgatgagctt atgcgcattc taaaagaagc
    54181 gctggaagtg gcagtgcagg aggcagacaa tgtctttgcc aatgtcaaaa taaatgtagg
    54241 agagatttta agtattgatg agaaacttga aaagtatact gagacgacac attagtctat
    54301 tgggctttct cggagtattg tcaatctggc agttagcagg ttttcttaaa cttctcccca
    54361 agtttatcct gccgacacct cttgaaattc tccagccctt tgttcgtgac agagaatttc
    54421 tctggcacca tagctgggcg accttgagag tggctttact ggggctgatt ttgggagttt
    54481 tgattgcctg tcttatggct gtgctcatgg atagtttgac ttggctcaat gacctgattt
    54541 accctatgat ggtggtcatt cagaccattc cgaccattgc catagctcct atcctggtct
    54601 tgtggctggg ttatgggatt ttgcccaaga ttgtcttgat tatcttaaca acaacctttc
    54661 ccatcatcgt tagtattttg gacggtttta ggcattgtga caaggatatg ctgactttgt
    54721 ttagtctgat gcgagcaaac ccttggcaaa tcctgtggca ttttaaaatc ccggttagcc
    54781 tgccttactt ttatgcaggt ctgagggtca gtgtctccta cgcctttatc acaactgtgg
    54841 tatctgagtg gttgggaggt tttgaaggtc ttggtgttta tatgattcag tctaaaaaac
    54901 tgtttcagta tgataccatg tttgccatta ttattctggt gtcgattatc agtcttttgg
    54961 gtatgaagct ggtcgatatc agtgaaaaat atgtgattaa atggaaacgt acttaaaata
    55021 gagcgttttt gaaaaagaaa agaggaaatc aaaatgaaga aaacatggaa agtgttttta
    55081 acgcttgtaa cagctcttgt agctgttgtg cttgtggcct gtggtcaagg aactgcttct
    55141 aaagacaaca aagaggcaga acttaagaag gttgacttta tcctagactg gacaccaaat
    55201 accaaccaca cagggcttta tgttgccaag gaaaaaggtt atttcaaaga agctggagtg
    55261 gatgttgatt tgaaattgcc accagaagaa agttcttctg acttggttat caacggaaag
    55321 gcaccatttg cagtgtattt ccaagactac atggctaaga aattggaaaa aggagcagga
    55381 atcactgccg ttgcagctat tgttgaacac aatacatcag gaatcatctc tcgtaaatct
    55441 gataatgtaa gcagtccaaa agacttggtt ggtaagaaat atgggacatg gaatgaccca
    55501 actgaacttg ctatgttgaa aaccttggta gaatctcaag gtggagactt tgagaaggtt
    55561 gaaaaagtac caaataacga ctcaaactca atcacaccga ttgccaatgg cgtctttgat
    55621 actgcttgga tttactacgg ttgggatggt atccttgcta aatctcaagg tgtagatgct
    55681 aacttcatgt acttgaaaga ctatgtcaag gagtttgact actattcacc agttatcatc
    55741 gcaaacaacg actatctgaa agataacaaa gaagaagctc gcaaagtcat ccaagccatc
    55801 aaaaaaggct accaatatgc catggaacat ccagaagaag ctgcagatat tctcatcaag
    55861 aatgcacctg aactcaagga aaaacgtgac tttgtcatcg aatctcaaaa atacttgtca
    55921 aaagaatacg caagcgacaa ggaaaaatgg ggtcaatttg acgcagctcg ctggaatgct
    55981 ttctataaat gggataaaga aaatggtatc cttaaagaag acttgacaga caaaggcttc
    56041 accaacgaat ttgtgaaata atgacagaaa ttagactaga gcacgtcagt tatgcctatg
    56101 gtcaggagag gattttagag gatatcaacc tacaggtgac ttcaggcgaa gtggtttcca
    56161 tcctaggccc aagtggtgtt ggaaagacca ccctctttaa tctaatcgct gggattttag
    56221 aagttcagtc agggagaatt gtccttgatg gtgaagaaaa tcccaagggg cgcgtgagtt
    56281 atatgttgca aaaggatctg ctcttggagc acaagacggt gcttggaaat atcattctgc
    56341 ccctcttgat tcaaaaggtg gataaggcag aagctatttc ccgagcggat aaaattcttg
    56401 cgaccttcca gctgacagct gtaagagaca agtatcctca tgaacttagc ggtgggatgc
    56461 gccagcgtgt agccttactc cggacctacc tttttgggca caagctcttt ctcttagatg
    56521 aggcctttag cgccttggat gagatgacaa agatggaact ccacgcttgg tatcttgaga
    56581 ttcacaagca gttgcagcta acaaccctga tcatcacgca tagtattgag gaggccctca
    56641 atctcagcga ccgcatctat atcttgaaaa atcgccctgg gcagattgtt tcagaaatta
    56701 aactagattg gtctgaagat gaggacaagg aagtccaaaa gattgcctac aaacgtcaaa
    56761 tcttggcaga attaggctta gataagtaga aaaataggga gttggtgaag attatccttt
    56821 accagcgccc tttttctttt aaaaatgaga aaatttcggt ataatagtca aacaaggtca
    56881 aggtttaaag agagaggtgg gtttgttatg agatttaaaa atacatcgga tcatattgag
    56941 gcctacatca aggcgatttt agatcaatct ggtatcgtgg agttgcaacg gagtcagttg
    57001 gcagatacct ttcaggttgt tcctagtcag attaactacg tgatcaagac acgctttacg
    57061 gaaagtagag gctacttggt tgaaagtaag cgtggtggtg gaggctacat tcgtatagga
    57121 cgaattgagt tttctagtca tcatgaaatg ctccgggagc tgctttactc gattggtgag
    57181 cgagtcagtc aagaaattta tgaggatatt ctccagcttt tggttgagca ggaattgatg
    57241 accaagcagg agatgaattt gctagaatca gtagctttgg atcgcgtttt aggagaagaa
    57301 gctccagttg ttcgagcaaa catgctacgt cagatcatac aagaggtaga tagaaaaggg
    57361 aagtaagatg aactattcaa aagcattgaa tgaatgtatc gaaagtgcct acatggttgc
    57421 tggacatttt ggagctcgtt atctagagtc ttggcacttg ttgattgcca tgtctaatca
    57481 cagttatagt gtagcagggg caactttaaa tgattatccg tatgagctgg accgtttaga
    57541 agaggtggct ttggaactga ctgaaacgga ctatagccag gatgaaactt ttacggaatt
    57601 gccgttctcc cgtcgtttgc agattctttt tgacgaagca gagtatgtag cgtcagtggt
    57661 ccatgctaag gtgctaggga cagagcacgt cctctatgcg attttgcatg atggcaatgc
    57721 cttggcgact cgtatcttgg agagggctgg tttttcttat gaagacaaga aagatcaggt
    57781 caagattgct gctcttcgtc gaaatttaga agaacgggca ggctggactc gtgaagatct
    57841 caaggcttta cgccaacgcc atcgtacagt agctgacaag caaaattcta tggccaatat
    57901 gatgggcatg ccgcagactc ctagtggtgg tctcgaggac tatacgcatg atttgacaga
    57961 gcaagcgtgt tctggcaagt tagaaccagt catcggtcgg gacaaggaaa tctcacgtat
    58021 gattcaaatc ttgagccgga agactaagaa caaccctgtc ttggttgggg atgctggtgt
    58081 cgggaaaaca gctctggcgc ttggtcttgc tcagcgtatt gctagtggtg acgtgcctgc
    58141 ggaaatggct aagatgcgcg tgttagaact tgatttgatg aatgtcgttg cagggacacg
    58201 cttccgtggt gactttgaag aacgcatgaa taatatcatc aaggatattg aagaagatgg
    58261 ccaagtcatc ctctttatcg atgaactcca caccatcatg ggttctggta gcgggattga
    58321 ttcgactctg gatgcggcca atatcttgaa accagccttg gcgcgtggaa ctttgagaac
    58381 ggttggtgcc accactcagg aagaatatca aaaacatatc gaaaaagatg cggctctttc
    58441 tcgtcgtttc gctaaagtga cgattgaaga accaagtgtg gcagatagta tgactatttt
    58501 acaaggtttg aaggcgactt atgagaaaca tcaccgtgta caaatcacag atgaagcggt
    58561 tgaaacagcg gttaagatgg ctcatcgtta tttaaccagt cgtcacttgc cagactctgc
    58621 tatcgacctc ttggacgaag cagcagcaac agtgcaaaat aaggtaaagt atgtaaaagc
    58681 agacgattca gatttgagtc cagctgataa ggccctgatg gatggcaagt ggaaacaggc
    58741 agcccagcta atcgcaaaag aagaggaagt acctgtctac aaagacttgg tgacagagtc
    58801 tgatattttg accaccttga gtcgcttgtc aggaatccca gttcaaaaac tgactcaaac
    58861 ggatgctaag aagtatctaa atcttgaagc agaactccat aaacgtgtca tcggtcaaga
    58921 tcaagctgtt tcaagcatta gtcgtgcgat tcgccgtaat cagtcaggaa ttcgcagtca
    58981 caagcgtccg atcggttcct ttatgttcct aggacccaca ggtgtcggta agaccgagtt
    59041 ggccaaggct ttggcagaag ttctctttga tgacgaatca gcccttatcc gctttgatat
    59101 gagtgagtat atggagaaat tcgcagccag ccgtctaaat ggagctcctc caggctatgt
    59161 gggttacgaa gaaggtggag agttgacaga gaaggttcgc aataaaccct attccgttct
    59221 cctctttgat gaggtagaga aggcccaccc agatatcttt aatgttctct tgcaagttct
    59281 ggatgacggt gttttgacag atagcaaggg acgcaaggtc gatttttcaa ataccattat
    59341 cattatgaca tcgaacctag gtgcgactgc ccttcgtgat gataagactg ttggttttgg
    59401 ggctaaggat attcgttttg accaggaaaa tatggaaaaa cgcatgtttg aagaactgaa
    59461 aaaagcttat agaccggaat tcatcaaccg tattgatgag aaggtggtct tccatagcct
    59521 atctagtgac catatgcagg aagtggtgaa gattatggtc aagcctttag tggcaagttt
    59581 ggctgaaaaa ggcattgact tgaaattaca agcttcagct ctgaaattgt tagcaaatca
    59641 aggatatgac ccagagatgg gagctcgccc acttcgcaga accctgcaaa cagaagtgga
    59701 ggacaagttg gcagaacttc ttcttaaggg agatttagtg gcaggcagca cacttaagat
    59761 tggtgtcaaa gcaggccagt taaaatttga tattgcataa aagaataaaa gtatcagcat
    59821 ctgaccataa gtcacagtgg agtgaaactc aatgaaaatc aaagagcaaa ctaggcagct
    59881 agccgcaggt tgctcaaaac actggtttga ggttgcagat agagctgacg tggtttgaag
    59941 agattttcga agagtatgaa actaaaacct atagcttcta aacgatccgt ggttttcacc
    60001 attcaacaca aaattcatat gtttattacc ctccgtcgta tttgtcttag agcgtgtgta
    60061 gtagaaaaag agcagtctta tctgaaattt ttattctttc aaaagagacc tgtttctttt
    60121 ttgcatgtca aatccgttct agctggtatt tgaaaaatca aactaatatt caatgaaaat
    60181 caaagaacaa actaggcagc tagccacagg ttgctcaaaa cactgttttt agattgtaga
    60241 tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat gaatgatttt
    60301 cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat tccattatca
    60361 tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg tatggagttc
    60421 tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga aatgattaga
    60481 gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc taaggatgga
    60541 caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact ggatttaatg
    60601 atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca cgatattcct
    60661 gtcatcgtct tgagtgctct gggagatgaa actactcagt cacaggtatt tgatctctat
    60721 gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg tattaaggcg
    60781 cttatcagac gttactacgt catagaggat atttggcgat atcaggatgt aacagtggat
    60841 tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc aaaggaatta
    60901 ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga gcagatattg
    60961 gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga tgtctatatt
    61021 cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa tgttgggtat
    61081 aagattagct tatgataaaa aatcctaaat tattaaccaa gtctttttta agaagttttg
    61141 caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc tttccttttt
    61201 attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt acggagtatt
    61261 taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca aagtccttga
    61321 ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt gtgcatgact
    61381 tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg tctgttagta
    61441 cagcagatgg taaacaggta acagtgcaat ttgttcacgg ggtggatatc tacaaagaag
    61501 caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt gctttttcct
    61561 ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac atttcagaag
    61621 tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt aggaaagatg
    61681 aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg aaggttattc
    61741 atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag gtttcctttg
    61801 tccgtggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt atcctagaga
    61861 atatgcagca taatattgga gattacaaag atcatccaaa atatattgca aagagtataa
    61921 ataagattga ccagatgagc cacttattag aagaagtact ggagtcttct aaattccaag
    61981 agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat attttatcac
    62041 gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg acagatgcta
    62101 ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacttg attagtaatg
    62161 caattaaata ttcagataaa aatgggcgcg taatcatatc cgagcaagat ggctatctct
    62221 ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta tttgatatat
    62281 tctatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt ctttacattg
    62341 tgaataatat tttagaaagc tatcaaatgg actatagttt tctcccttat gaacacggta
    62401 tggaatttaa gattagcttg tagacagatt agttttttat taaagttcat atagggttaa
    62461 cataagtgtg ttattctttg catagataaa agaaaggata ctaatatggt attagcgatt
    62521 attttagtaa cattctttat tcgattgatt tttttaaagc gttcgataga gaatgagaaa
    62581 cgaatcctta gcaatggcgg gaaagaattt ggagttgaga atacaaaacg attaactatg
    62641 gctcatattg ttttttatct ctcttgcttg gttgaggcag tggtgcacaa gacaattttt
    62701 gatggcatgg gtatggttgg tttggtcttg cttatttttt ctatgctgat gttgatgttg
    62761 gtgattcact tgttgggaga tatttggaca gtgaagctta tgcttgtcaa taatcacaaa
    62821 tatgtagatc atatcttgtt taggacagta aaacatccta attacttttt aaatattctt
    62881 cctgagttga ttggcttgac cttgttgagt catgcttatg tgacttttgt tttagttttt
    62941 ccagtttatg cagttatttt gtatcgacga atagctgaag aggaaaagct attacatgaa
    63001 gttataatcc caaatggaag cataaagaga taaatacaaa attcgattta tatacagttc
    63061 atattgaagt gatatagtaa ggttaaagaa aaaatataga aggaaataaa catgtttgca
    63121 tcaaaaagcg aaagaaaagt acattattca attcgtaaat ttagtattgg agtagctagt
    63181 gtagtagttg ccagtcttgt tatggggagt gtggttcatg cgacagagaa cgagggaagt
    63241 acccaagcag ccactttttc taatatggca aataaaagtc agacagaaca aggagaaatc
    63301 aatatagaac gagataaggc aaagacagcg gtcagtgaat ataaagaaaa aaaagtgagt
    63361 gagatctata caaaattaga gagagataga cataaagata ctgtagatct agttaacaag
    63421 ttgcaagaga ttaagaacga gtatttgaat aaaatagttc aatcaacctc aaaaaccgaa
    63481 atacagggac ttattacaac aagtcgatca aaactagatg aagctgtgtc taaatataaa
    63541 aaggccccat cttcttcgtc aagttcaggc tcttccacta aaccggaagc ttcagataca
    63601 gcgaagccaa acaagccgac agaactagaa aaaaaggtag cagaagctga gaagaaggtt
    63661 gaagaagcta agaagaaagc caaggatcaa aaagaagaag attaccgtaa ctacccaacc
    63721 attacttaca aaacgcttga acttgaaatt gctgagtccg atgtggaagt taaaaaagcg
    63781 gagcttgaac tagtaaaaga ggaagctaag gaacctcgaa acgaggaaaa agttaagcaa
    63841 gcaaaagcga aagttgagag tgaagaaact gaggctacaa ggttagaaaa aatcaagaca
    63901 gatcgtaaaa aagcagaaga agaagctaaa cgaaaagcag cagaagaaga taaagttaaa
    63961 gaaaaaccag ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctcca
    64021 aaaccagaga atccagctcc aaaaccagag aatccagctc caaaaccaga aaaaccagct
    64081 gaacaacaag ctgaagaaga ctatgctcgt agatcagaag aagaatataa tcgcttgact
    64141 caacagcaac cgccaaaaac tgaaaaacca gcacaaccat ctactccaaa aacaggctgg
    64201 aaacaagaaa acggtatgtg gtacttctac aatactgatg gttcaatggc gacaggatgg
    64261 ctccaaaaca atggctcatg gtactacctc aacagcaatg gcgctatggc gacaggatgg
    64321 ctccaaaaca atggttcatg gtactatcta aacgctaatg gttcaatggc aacaggatgg
    64381 ctccaaaaca atggttcatg gtactaccta aacgctaatg gttcaatggc gacaggatgg
    64441 ctccaataca atgg
//
LOCUS       DAVBOU010000005        60624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBOU010000005 DAVBOU010000000
VERSION     DAVBOU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.005"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            131..412
                     /locus_tag="VQ879_000275"
                     /pseudo
     CDS             131..412
                     /locus_tag="VQ879_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(537..740)
                     /locus_tag="VQ879_000276"
     CDS             complement(537..740)
                     /locus_tag="VQ879_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142504.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(733..1815)
                     /locus_tag="VQ879_000277"
     CDS             complement(733..1815)
                     /locus_tag="VQ879_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3142505.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1941..2723)
                     /locus_tag="VQ879_000278"
     CDS             complement(1941..2723)
                     /locus_tag="VQ879_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3142506.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2723..4066)
                     /locus_tag="VQ879_000279"
     CDS             complement(2723..4066)
                     /locus_tag="VQ879_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3142507.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4165..5481)
                     /locus_tag="VQ879_000280"
     CDS             complement(4165..5481)
                     /locus_tag="VQ879_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3142508.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5675..6901
                     /locus_tag="VQ879_000281"
     CDS             5675..6901
                     /locus_tag="VQ879_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3142509.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7100..8674
                     /locus_tag="VQ879_000282"
     CDS             7100..8674
                     /locus_tag="VQ879_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3142510.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8939..9727
                     /gene="codY"
                     /locus_tag="VQ879_000283"
     CDS             8939..9727
                     /gene="codY"
                     /locus_tag="VQ879_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3142511.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9727..10302
                     /locus_tag="VQ879_000284"
     CDS             9727..10302
                     /locus_tag="VQ879_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3142512.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10384..10469
                     /locus_tag="VQ879_000285"
     tRNA            10384..10469
                     /locus_tag="VQ879_000285"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10418..10420,aa:Leu,seq:aag)
     gene            10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ879_000286"
     CDS             10752..11882
                     /gene="ugpC"
                     /locus_tag="VQ879_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3142513.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12383..13141
                     /locus_tag="VQ879_000287"
     CDS             12383..13141
                     /locus_tag="VQ879_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3142514.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13228..13740
                     /locus_tag="VQ879_000288"
     CDS             13228..13740
                     /locus_tag="VQ879_000288"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3142515.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13922..14866
                     /locus_tag="VQ879_000289"
     CDS             13922..14866
                     /locus_tag="VQ879_000289"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3142516.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14875..15552
                     /locus_tag="VQ879_000290"
     CDS             14875..15552
                     /locus_tag="VQ879_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3142517.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15650..16408
                     /locus_tag="VQ879_000291"
     CDS             15650..16408
                     /locus_tag="VQ879_000291"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3142518.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16446..17951
                     /gene="lytC"
                     /locus_tag="VQ879_000292"
     CDS             16446..17951
                     /gene="lytC"
                     /locus_tag="VQ879_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3142519.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18448..18966
                     /locus_tag="VQ879_000293"
     CDS             18448..18966
                     /locus_tag="VQ879_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3142520.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19096..19602
                     /locus_tag="VQ879_000294"
     CDS             19096..19602
                     /locus_tag="VQ879_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3142521.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19804..21036
                     /gene="clpX"
                     /locus_tag="VQ879_000295"
     CDS             19804..21036
                     /gene="clpX"
                     /locus_tag="VQ879_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3142522.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21045..21632
                     /locus_tag="VQ879_000296"
     CDS             21045..21632
                     /locus_tag="VQ879_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3142523.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21643..22023
                     /locus_tag="VQ879_000297"
     CDS             21643..22023
                     /locus_tag="VQ879_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3142524.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ879_000298"
     CDS             22075..22965
                     /gene="rapZ"
                     /locus_tag="VQ879_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3142525.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22962..23939
                     /locus_tag="VQ879_000299"
     CDS             22962..23939
                     /locus_tag="VQ879_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3142526.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23936..24847
                     /gene="whiA"
                     /locus_tag="VQ879_000300"
     CDS             23936..24847
                     /gene="whiA"
                     /locus_tag="VQ879_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3142527.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24881..25849)
                     /locus_tag="VQ879_000301"
     CDS             complement(24881..25849)
                     /locus_tag="VQ879_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3142528.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25985..26842
                     /locus_tag="VQ879_000302"
     CDS             25985..26842
                     /locus_tag="VQ879_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3142529.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26829..27608
                     /locus_tag="VQ879_000303"
     CDS             26829..27608
                     /locus_tag="VQ879_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3142530.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27632..28984
                     /locus_tag="VQ879_000304"
     CDS             27632..28984
                     /locus_tag="VQ879_000304"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3142531.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29058..29432
                     /locus_tag="VQ879_000305"
     CDS             29058..29432
                     /locus_tag="VQ879_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3142532.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29434..30282
                     /locus_tag="VQ879_000306"
     CDS             29434..30282
                     /locus_tag="VQ879_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3142533.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30559..31326
                     /locus_tag="VQ879_000307"
     CDS             30559..31326
                     /locus_tag="VQ879_000307"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3142534.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31338..32522
                     /locus_tag="VQ879_000308"
     CDS             31338..32522
                     /locus_tag="VQ879_000308"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3142535.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32519..34390
                     /locus_tag="VQ879_000309"
     CDS             32519..34390
                     /locus_tag="VQ879_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3142536.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34533..35717)
                     /gene="mntE"
                     /locus_tag="VQ879_000310"
     CDS             complement(34533..35717)
                     /gene="mntE"
                     /locus_tag="VQ879_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3142537.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36021..38717
                     /locus_tag="VQ879_000311"
     CDS             36021..38717
                     /locus_tag="VQ879_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3142538.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38730..39521
                     /gene="yghU"
                     /locus_tag="VQ879_000312"
     CDS             38730..39521
                     /gene="yghU"
                     /locus_tag="VQ879_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3142539.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39637..40047
                     /locus_tag="VQ879_000313"
     CDS             39637..40047
                     /locus_tag="VQ879_000313"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3142540.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40059..41654
                     /locus_tag="VQ879_000314"
     CDS             40059..41654
                     /locus_tag="VQ879_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142541.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41721..41885
                     /locus_tag="VQ879_000315"
     CDS             41721..41885
                     /locus_tag="VQ879_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3142542.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41964..42692
                     /gene="yaaA"
                     /locus_tag="VQ879_000316"
     CDS             41964..42692
                     /gene="yaaA"
                     /locus_tag="VQ879_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3142543.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42969..43517)
                     /locus_tag="VQ879_000317"
     CDS             complement(42969..43517)
                     /locus_tag="VQ879_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3142544.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43838..44326
                     /locus_tag="VQ879_000318"
     CDS             43838..44326
                     /locus_tag="VQ879_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3142545.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44323..45510
                     /locus_tag="VQ879_000319"
     CDS             44323..45510
                     /locus_tag="VQ879_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3142546.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45503..45868
                     /locus_tag="VQ879_000320"
     CDS             45503..45868
                     /locus_tag="VQ879_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3142547.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            45884..47230
                     /gene="asnS"
                     /locus_tag="VQ879_000321"
     CDS             45884..47230
                     /gene="asnS"
                     /locus_tag="VQ879_000321"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3142548.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47383..47673
                     /locus_tag="VQ879_000322"
     CDS             47383..47673
                     /locus_tag="VQ879_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3142549.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47685..48155
                     /gene="ssbA"
                     /locus_tag="VQ879_000323"
     CDS             47685..48155
                     /gene="ssbA"
                     /locus_tag="VQ879_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3142550.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48187..48426
                     /locus_tag="VQ879_000324"
     CDS             48187..48426
                     /locus_tag="VQ879_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3142551.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48721..50121
                     /locus_tag="VQ879_000325"
     CDS             48721..50121
                     /locus_tag="VQ879_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3142552.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50123..50482
                     /locus_tag="VQ879_000326"
     CDS             50123..50482
                     /locus_tag="VQ879_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3142553.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVLDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50536..51285
                     /locus_tag="VQ879_000327"
     CDS             50536..51285
                     /locus_tag="VQ879_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3142554.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51275..51574
                     /locus_tag="VQ879_000328"
     CDS             51275..51574
                     /locus_tag="VQ879_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3142555.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51645..52580
                     /locus_tag="VQ879_000329"
     CDS             51645..52580
                     /locus_tag="VQ879_000329"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3142556.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52666..53178
                     /locus_tag="VQ879_000330"
     CDS             52666..53178
                     /locus_tag="VQ879_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3142557.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53215..53810
                     /locus_tag="VQ879_000331"
                     /pseudo
     CDS             53215..53810
                     /locus_tag="VQ879_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53911..54105
                     /locus_tag="VQ879_000332"
     CDS             53911..54105
                     /locus_tag="VQ879_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3142558.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(54151..55596)
                     /locus_tag="VQ879_000333"
     CDS             complement(54151..55596)
                     /locus_tag="VQ879_000333"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3142559.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55702..57324
                     /locus_tag="VQ879_000334"
     CDS             55702..57324
                     /locus_tag="VQ879_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3142560.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57527..59485
                     /locus_tag="VQ879_000335"
     CDS             57527..59485
                     /locus_tag="VQ879_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3142561.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59657..60217
                     /locus_tag="VQ879_000336"
     CDS             59657..60217
                     /locus_tag="VQ879_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142562.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            60218..60592
                     /locus_tag="VQ879_000337"
     CDS             60218..60592
                     /locus_tag="VQ879_000337"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142563.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT        17885 a        11272 c        13719 g        17748 t
ORIGIN      
        1 aagaaagaca gaaattgttc aagaattaat gactgagttt tcgttagttc ttcttctaaa
       61 agccattaaa ctagctcgtt cgacctacta ctatcacttg aaacagctag acaaaacaga
      121 taaggactaa ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg
      181 aattcaagca tctatgtcac gcaagggaaa cagccaagac aacggtatga tggagtcctt
      241 ctttggcatt ttaaaatccg aaatgtttta tggctatgag aaaacattta aatcacttaa
      301 tcaattggaa caagccatta tagactatat tgattattac aacaataaga aaattaagtt
      361 aaaactaaaa ggacttagcc ctgtgcaata cagaactaaa tccttcggat aaattaattg
      421 tctaactttt tgggggcagt acacaatacc tgatagtatg cgttttattg tgggaagatt
      481 ttcctcattt tctagtgaaa ttgaactttt tctaacatct tttgatagat gacttcttaa
      541 tcaattatca tttccattgt tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg
      601 agagcaccct cgttatcatt ccagacactt agggttagat tattgcagcc aatttcttta
      661 gcataatagc agaaaaatga caataaaata gcccctagat attttgaaag gaaagcatag
      721 gggctatata gtttaatcaa aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa
      781 gccatccttg gtaacaacac cgcagtcttc aatacgaaca ccgactttac cagggatata
      841 gatacctggt tcaacagaga agcacatgcc ttcttcgatg accatgtcgt ttccttccat
      901 gatagatggg aattcatgga catccatacc gataccatgc ccgagacggt gattgaagta
      961 ctcaccataa ccagcttttt cgatgacctc acgggcagcg cggtccactt catgagcagt
     1021 cacacctggc ttgataaagt caagagcagc ttgttgggct tcaagagtca agttgtaaat
     1081 atctttcttg aattggtctg gtttgccgac agcgactgta cgagtcatat ctgacgcata
     1141 gccattgacc agaacaccca ggtcaaagag gagaagagca tcattttcaa ccttattagc
     1201 tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc aagaccatgg tatcaaagct
     1261 catttcataa ccttcacgtt tcatggcaaa gtcgatttgt gcgatgatat ctgtctcagt
     1321 cttatcaaga gaaatattgt caaaaccaac atgaacagcc ttgtcagcat aaagacctgc
     1381 aaccatcatt ttttgcactt catcagctga tttgatgagg cgcatgcgtt ggatacgagg
     1441 agtgaggttg tcaaactcag cagtctcaaa aactgttttc aaaccatggt atttggtcaa
     1501 gatgagattg tcaaactcaa cagcgacacg tttgaagtca agttgtggaa gagcatgttt
     1561 gattttttgc catggatttt cagaatcgac atagcccact actgggaagg aaacggtgct
     1621 acttgcacgt tctacttcaa gagctgggac aaagaggaga ggttcctgat ccgctaggac
     1681 aaagaggaac atttggcgtt catggggatc actgtaaaaa ccagtgaggt aattgattgt
     1741 gacggggtca gatacgacag cgacgtctag tttttctgat tcaagatatg ttaggatttg
     1801 ttgtaattta gacatatgct accttctttc tacccctcta ttttggcaaa aaatgagaga
     1861 aaatgcaagg gagaagggta aaagaaaaga caaaaaactc cgacaagata acggagttct
     1921 ttgatatcat tttcctttgt ttaagaaaag tcagccttgc ttttgacgtc actgtactct
     1981 tcagcgattt cttggctgag gatatcctca taggcaggga gttggatatc ctgaccatat
     2041 ttcttcttga gggcagtagt aactaggcga taagccagat tggcattacg agagaggata
     2101 ggcccgtgga agtaggaacc aaagacattc ttataatgaa ccccttcacc gaccttttct
     2161 tcgttgtttc catttccata gacaacctgt cccagcggtt tttggtcatc agagaggaag
     2221 gtacggcctt ggtgattttc aaatccatag taggtttcat cgaaatcttc attgtgaatc
     2281 ttgatgtcac cgataaaacg gttattggtc tggttgagcg tgtagtgtcc catgacccct
     2341 agcccttcga tacgttttcc tgaagcttca acataatatt gacccaatag ttggaaacca
     2401 ccgcagatag ccagaactac accgtcgttt tggatgtagt tgtcaatgct ctctttttta
     2461 gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg
     2521 atgtcgtagt gattttcatc aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg
     2581 gctcccagtt tttcagccac atatttgagc atgaggatgt ttccattgtc cccgtaggta
     2641 ttcatgagat ttccgtagag gtgggcaatg ttgagctgat aggggtaatt gccatctttt
     2701 gaggaaagtg aagtataaac cattagttca tctcctttct aacaatctga cgactagcca
     2761 gcagttcacg aaattccagc atggcagtat aagttgccag aatataggca tgcttgcagt
     2821 cttgattctc aatggtcttg agaacttgct ccagattact cgtttcagtg attttctcag
     2881 ctggatagcc agtcactcgg aggcgacgag cgatttcaga atgacgaaca ccgccagcgt
     2941 tgatttcagg aatgtccatg tcagtgattt gctcaaagtc tgcatcccag atccagctag
     3001 tgtcaattcc atctgcatag ttggcattaa ggaggacaga taggctaaat ggataaggtg
     3061 ctagtttgat catttcgata gcttgggttg caccgactgg atttttaatc aagacaaggg
     3121 tacatttctt gtcaccgata tgaaaggttt cttggcgtcc aaagacagca cggctcttgt
     3181 caaatccctg tttgatgagt tgcgaatcgg cacctaggaa acgggcgatg gccacagcag
     3241 ctagggcgtt atagatatta tagagcccgc cgatttggat accgtattct tggccgtcta
     3301 tgacaaagcg agagcgattg ttggtcaact caaccagttt tgtcaaacga tagtcgagat
     3361 caggacgttt acatccacaa ccttcacaga tataggcacc caagtttgca taggtattat
     3421 gctcatattt gaggatgcct tggcagtcag gacagagaat cccttcggta ttgtagtgag
     3481 ccagttgggc tggtcctttt tccaagtcaa aaccaaaata ctctataggg tttggaatag
     3541 ttggcttgta gaaaagtgga ctgtctccgt taaggagaac agtagcagtt ggaacttttc
     3601 gaatggcatc caatatcatg ttataggtag tatagatttc accgaaacgg tccatctggt
     3661 cacggaagat attagtaatg acaaaaagac taggctggat atagtcacag atacgagata
     3721 gactggcttc gtcaatttcg aggacggcaa tatttttccc agtttttgaa gatttggctg
     3781 ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc gcttgggttg gttagaactt
     3841 gaccataaac ctcttttaaa atgccgacag tgagggcagt tgtcagggtt tttccatttg
     3901 ttccagtgac aacgacaatc tcgtagttct tagctaggtt ttgtaaaata tctttatcaa
     3961 attgaagggc gactttacct gggagcgtac ttccacgtcc aagacggctt aaaacgaagt
     4021 gggaagaacg cccagcaaga aggcccaaag tagtttttaa gttcatgttt ctattatatc
     4081 acaaaagagg gaaaagacag atttggtgtt tcgtagaagt aaaaacagcc caaagagggc
     4141 tgtcagttaa gatgagattt caacttaaat cgcaaacaag tcattcaagt tctcagccaa
     4201 ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc
     4261 aacagtaatg atgttgatga tttcttgaga accttctgag aagatgcttg caccaagaat
     4321 ttcttttgtt tcagtattaa caacagcttt gaaagctccg cgaaggtctc catttacgtg
     4381 accacgaggc atggctgcaa cagggatttc tttcactgcg tatggaagtt tcaaatcagc
     4441 tgcttggctt tcagtcaaac caacttgtga aagtgcaggt gtgatgaaca tagtatttgg
     4501 cacattgaga cggtcctcaa gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac
     4561 acggaagtca tcaagtgaaa tgtaagtaaa ttgaagacca ccgttgacat ctccaactgc
     4621 aaagacacca ggaacgtttg tttgacagtg tttatctact ttaatagcgc cacgttcagt
     4681 tagttcaata tctgtatttt caagttgaag tggttctaca tttggtttgc gtccagttgc
     4741 gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt acgacaagca cttggtcacc
     4801 gtcgttttta atttcagtag tatggatatt ttgaagcaat tcaataccgt cttcttccag
     4861 gtattgttta gcaagagctg cgatggaagg ttctgcacga ggtaggaatg tatccaaggc
     4921 atctaggact gtaaccttgc ttcctagttt attgtaaagg ccagcaaatt caagaccgat
     4981 atttccgcca ccaaggactc caagtttttc aggcaattta tccaagcttt ggatacctgt
     5041 tgagtcaaag acgtttttgc ttgtagcaag tccagggatt ggcaagacgt ttgaaacagc
     5101 accagtgttg atgacgatag tttcagcagt caattcttgt ttttcatcac cagcttggat
     5161 ttcgatgact ttatttgaaa ggaagtgagc ttcagcatca aagatattga cgccagtacc
     5221 agcaacagtc gtatagtttt taccgttgag gcgaccagtg atcgtgtttt tggtagcaat
     5281 gacttcttca aaagacaagt ctttctcagc agcaaccagc aaagttttag ttgggataca
     5341 accgatgttg atacaagttc caccgtacat agctttgcta cgttcaacga gggcaacttt
     5401 tttgccagct gaagccaatt taccagctag tgttttacca gctttaccaa atccgataac
     5461 gattaaatca taagttaaca tttagaattc ctcctattcg aattacattc tagcacaaga
     5521 aaaaaacttt tgcacaattc tgctacgaaa aagacagaaa aagatgaaaa cgctttccag
     5581 acaaaaaact agtaattttt tgacaagctt gataaactaa aatcctatct atttttatat
     5641 aataaagaat aaatgttcga aaataggagg ttttatgaaa tcgaatcgtt atattattgc
     5701 ctttgctggg gtcattttac acttaatgct gggttcgact tatgcctgga gtgtttatcg
     5761 taaccctatt attgaaaaaa cgggatggga tcaggcttct gttgccttcg cctttagtct
     5821 agcaatcttt tgtttgggct tatcggctgc atttatgggg cgtttggtag aaaaatttgg
     5881 tccgaaagtc atgggaagtc tatctgcttt tctatacgca ggtggaaata tcttaacagg
     5941 atttgcaata gaccgtcagg agctgtggtt gttgtatctc gcttatggca ttttaggtgg
     6001 gcttggtttg ggagcaggct atattacccc tgtgtcgacg attataaaat ggtttcctga
     6061 taaacgtggt ctcgcaacag gtttagcgat tatggggttt ggttttgctt ctttattgac
     6121 tagtcccata gcgcaacacc tcatcgcagg ggtagggctt gtagaaactt tttatatttt
     6181 aggagcaagt tactttatta tcatgctcct agcttcacaa ttcattaagc gtccaaatga
     6241 gcaagagctt gcaattttat cttcttcagg gaaagaaaaa acagcctctt tgacgcaagg
     6301 aatggctgca aatcaggctc taaaaagcaa tcggttttat atgctttgga ttattttctt
     6361 tatcaacata gcttgtggtt taggcttaat ttcagcggca tcgccaatgg cacaggagat
     6421 ggctggcttg tctacaagtc atgcagcagt aatggtgggt gttttgggga ttttcaatgg
     6481 atttggtcgc ttgctctggg cgagtttgtc tgactatatc ggtcgccctc taacctttag
     6541 tatattactg cttgttaatc ttttcttttc tctctcactt tggctcttta cagattccgt
     6601 tttatttgta gtcgctatgt ctattttgat gacttgctat ggagctggtt tttcattgat
     6661 cccagcttat ctcagtgata tttttggaac caaggaattg gccgctctgc atggatatat
     6721 tttaacagct tgggcaatgg ctggtttagc gggacctatt ttattagcag agacttataa
     6781 aatggctcat tcgtacacac aaaccttgtt cgtttttctc attttataca gtatcgcctt
     6841 ggctttgtct tattatctag gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg
     6901 attttctgta gaaatgggac tatcttttgc tctggtcttg tgttatacta gataggttgc
     6961 aaagaaaaca gtacttttct tttgtggaaa agaagcaaca cgattttata tctagttata
     7021 tgaaaatacg tcataaaaag aaaagtataa actaagccct atagggtggc ttcgcaccac
     7081 ctttagaaag aagaataacg tgaaatttaa tgaattaaac ttgtctgctg atttgctggc
     7141 agaaattgaa aaagctggtt ttgtagaagc tagtcctatc caagaacaaa ctattccttt
     7201 ggcccttgaa ggcaaggatg ttatcggtca agctcagact ggtacaggaa aaactgcagc
     7261 ctttggcttg cctacccttg aaaaaatccg tacagaagaa gcgactatcc aagccttagt
     7321 catcgctcca actcgtgaac tagctgtcca aagtcaagaa gaactcttcc gctttggtcg
     7381 tagtaaggga gtcaaagtcc gttcagtata tggcggatca agcattgaaa aacaaattaa
     7441 ggctcttaaa tctggtgccc atatcgtggt gggaactcca ggtcgcctct tggacttgat
     7501 taaacgcaag gccttgaaat tacaaaacat tgaaaccctt atccttgacg aagcggatga
     7561 aatgcttaac atgggcttcc ttgaagacat cgaagccatt atttcccgtg tacctgagaa
     7621 ccgtcaaact ttgcttttct cagcaactat gccagatgcc atcaaacgta tcggtgttca
     7681 gtttatgaaa gcccctgaac atgtcaagat tgcggctaag gaattgacaa cagaattggt
     7741 tgaccagtac tatatccgtg ttaaggaaca agaaaaattt gacaccatga ctcgtctcat
     7801 ggatgtggca caaccagaac tcgctattgt atttggtcgt accaaacgcc gtgtggatga
     7861 attgactcgt ggtttgaaaa ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga
     7921 ccaaaacaaa cgtcttcgtg tccttcgtga ctttaaaaat ggcaatcttg atgttttggt
     7981 tgcgacagac gttgcagcgc gtggtttgga tatttcaggt gtgacccatg tctacaacta
     8041 cgatattcca caagatcctg agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg
     8101 taagtcaggt caatctatta cttttgttgc tccaaacgaa atgggttacc ttcaaatcat
     8161 tgaaaacttg actaagaaac gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt
     8221 ccaatcaaaa aaacaggtag ctctcaagaa aatcgaacgt gattttgcag atgaaaccat
     8281 tcgtgccaat tttgagaaat ttggtaagga tgctcgcaaa ttggctgctg agtttactcc
     8341 agaagaattg gcaatgtata tcttgagtct gacagtccaa gacccagata gccttccaga
     8401 agtggagatt gcacgtgaaa aaccactacc gtttaaacca tcaggtaatg gtttcggtgg
     8461 taaagctaag ggaggtcgtg gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg
     8521 tggcaatggt cgccgtgatg agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa
     8581 ggaaaaacgt taccgtaagg ataataaaaa accacgcaat actttaagcg aaaagcaaac
     8641 aggctttgtt attcgtaaca aaggtgataa ataagaaaaa gcggttcaaa atgaatcgct
     8701 tttttatata aggagaccga atgtgaaaaa gacaaataaa attattatat tatcttttat
     8761 aatattatga tacacaaaaa taggcaactt gtcaatagaa aaggaacaat ttaattaaaa
     8821 atattctggt ttttaattaa attgtaagtc aatgcaagtc aataaggaat tttcagataa
     8881 ttattgaaaa agagacgttt ttatgttata atgatagcga ttaaattcga ggtgaaaaat
     8941 ggcacattta ttagaaaaaa ctagaaaaat tacatcaatt ttgaaacgct cagaggagca
     9001 gttgcaggat gagcttcctt acaacgctat tacgcgtcag ttagcggata ttattcattg
     9061 caatgcctgc attatcaata gtaagggacg tctgcttggc tattttatgc gttataaaac
     9121 aaatacagat cgcgtagagc aattcttcca aactaagatt ttcccagatg actacgttca
     9181 aggggctaat atgatttacg aaacagaagc aaacttacct gttgagcatg atatgagtat
     9241 tttccctgtt gagagtagag atgattttcc agatggcttg acgactattg caccgattca
     9301 tgtatcgggg attcgccttg gttctttgat tatttggcgt aatgataaaa aattcgaaga
     9361 tgaggacttg gttcttgttg agattgccag taccgttgtt gggattcagc ttcttaactt
     9421 ccaacgtgaa gaagatgaga aaaatattcg tcgtcgtact gctgtcacca tggcggtcaa
     9481 taccctttct tactccgaac tccgtgctgt ttcagcaatt ttaggggaat taaatggaaa
     9541 tgaagggaag ttgactgcgt cagtgattgc agatcgtatc ggaatcactc gctctgtgat
     9601 tgtcaatgct cttcgtaaac ttgagtctgc ggggattatt gaaagtcgct cacttggaat
     9661 gaagggaacc tatcttaagg tcttgatttc agatattttt gaagaagtga agaaaagaga
     9721 ttactaatga caaaggcttt aatttcgatt gattatacag aagattttgt tgctgatagt
     9781 gggaaactaa cagcaggtgc tccagctcag gcgatttcgg atgccatcag caaggtaact
     9841 cgattagctt ttgaacgagg agattatatc ttctttacta ttgatgctca tgaagaaaac
     9901 gattgtttcc atccggaaag taagttattt cctcctcata atctgattgg gacgagtgga
     9961 cggaatttat atggagattt ggggaacttt tatcaagagc atggttcaga cagtcgtgtc
    10021 ttttggatgg ataaacgcca ttactcagct ttttcaggga ctgacctaga tattcgtttg
    10081 agagagcgta gagtgtctac cgttatctta acaggtgtct tgacggatat ctgtgtccta
    10141 catacagcta tagatgccta taatctagga tatgacatcg agattgttaa accagctgtt
    10201 gcttccatct ggcctgaaaa tcatcaattt gccctaggtc atttcaaaaa tacactcgga
    10261 gctaagttag tagatgaaaa tctaaatgaa ctttctgagt aacctggttg gtgaaaatga
    10321 aaaaatttga aaaaaagtgt tgacaagcat cccaaaagtt gatatactag taaagtaatc
    10381 gatgcgggga tggcggaatt ggcagacgcg caggactaag gatcctgtga ccgctttagg
    10441 tcgtgagggt tcaagtccct ctctccgcat aggaaaagag ttagctaaag ctagctcttt
    10501 tgtatttctc taaaaaatta gaatccagtc aaatgtagtg gagaatcagc gaaaatatgg
    10561 gaaaactgat ccttgtttct gcttttgtca tagaagaata ataaagatta tcttcttcaa
    10621 attctccgat attctctaaa gttttgtgca agttgcacag aactttttta tttttttggt
    10681 catcttgcca tagaaatata aagcgttttc atatataata taattatcaa aagacaaaag
    10741 gagttcacct catggtagaa ttgaatctta aaaatattta caaaaaatat ccaaacagcg
    10801 aacactattc agttgaagat ttcaacttga acatcaaaga taaagaattt atcgttttcg
    10861 taggaccttc aggatgtggt aaatcaacta cactccgtat gattgctggt cttgaagaca
    10921 ttacagaagg tactgcatct atcgatggcg tggttgtcaa cgacgtagct ccaaaagacc
    10981 gtgatatcgc catggtattc caaaactacg ctctttaccc acacatgact gtttatgaca
    11041 acatggcttt cggtttgaaa ttgcgtaaat acagcaaaga agacattaac aaacgtgttc
    11101 aagaagcagc tgaaatactt ggattgaaag aattcttgga acgtaaacca gctgaccttt
    11161 caggtggtca acgtcaacgt gttgccatgg ggcgtgcgat tgtccgtgat gcgaaagtat
    11221 tcttgatgga cgaacctttg tcaaacttgg atgccaaact tcgtgtatca atgcgtgctg
    11281 aaatcgctaa aattcaccgt cgtatcggag ctacaactat ctatgtaact cacgaccaaa
    11341 cagaagcgat gacacttgca gaccgtatcg ttattatgtc agctactaag aaccctgctg
    11401 gtacaggtac tatcggacgt gtagaacaaa tcggcactcc tcaagaagtt tacaaaaatc
    11461 cagttaacaa attcgttgca ggattcatcg gaagcccagc tatgaacttc atcaacgtga
    11521 aattggttgg tagcgaaatt gtttctgacg gtttccgttt gaaagtgcca gaaggagcat
    11581 tgaaagttct tcgtgaaaaa ggctacgaag gaaaagaatt gatctttggt atccgtccag
    11641 aagacgtgaa tgcagaacct gctttccttg aaacattccc agactgtgtt gtaaaagcga
    11701 ctatctctgt atcagaactg cttggttcag aatctcacct ttactgccaa gttggtaaag
    11761 acgagtttgt tgcaaaagtt gatgctcgtg actacttgca aacaggtgca acagttgagc
    11821 ttggatttga cttgaacaaa gcacacttct tcgatgtaga aactgaaaaa acaatctact
    11881 aaaataaata aaattcaaag cactacaaga aaagatattt ctttatcaat tgtagtggag
    11941 agatatcagt taatctaggg agagaaacaa aatgcttctc tcctttttgc tagggaagtc
    12001 atattatgca tctatattgt gatgctcttt aatactcttc gaaaatctct tcaaaccacg
    12061 tcaacgtcgc cttgccgtac gtatgattac tgacttcgtc agttttatct gcaacctcaa
    12121 agctgtactt tgagcagttt acggctagtt tcctagtttg ctctttgatt tccattgagt
    12181 attatttgtg ggtaccatct acaagtgaag ctatatgcgt aaactacgtg agcaattgaa
    12241 ttcgaactag agaggtaata ataaatttat gctatagtta tggtgacttg tatgcttttg
    12301 attctagttt atcaaataat agattagaat tgtcagataa tatcattttg tgttataatg
    12361 aagaaaaaac agaggtgttc aaatgtcaga agcaggtcat aagtttttag caaaattggg
    12421 gaaaaaacgc ttacgtccag gtggaaagcg tgccacagat tggttaattg cagaaggagg
    12481 attttcaaaa gaaaagagaa tactagaggt tgcgtgtaat aggggaacta cagcaattga
    12541 gttggcacag cgttttggtt gcaagataac tgctgttgat atggatgctc aagctttaga
    12601 agtggctaaa aaatctgctg gaacggcagg tgttgctcat ttaatcagtt ttgaaagagc
    12661 aaatgcaatg aaacttcctt atcaagatgc tagttttgat attgttataa atgaagctat
    12721 gctgactatg caagccgatc aagctaagaa aaaatgtgta atggaatatc taagggtatt
    12781 aaaacctgga ggtcttctct tgacacatga tgtacttctt aaggaagcta aagagtctat
    12841 cagacaggaa ttatcacaag caattcatgt aaatgtaggt cctttaactc aagatggttg
    12901 ggaacaggtg atgatagaat caggttattg tgatgtgaaa gcattgactg gtgaaatgac
    12961 attaatgaaa ttatcgggta tgatttatga cgaaggtttg ctaggaactt tgaaaatttg
    13021 tgtaaatgct tgtaaaaagg agaatagaaa gcagttttta actatgtata aaatgtttgc
    13081 taagaataaa cagaaattgg gctttattgc gatggctagt tataaatcgt caaaacgtta
    13141 gataattatt gaagttaact tttccttttt tctttcttaa aaaatatgct ataatagaga
    13201 gtaaaaaact ttgaaagaaa gaaaaagatg aatttaaaag attacattgc aacaattgaa
    13261 aattatccaa aggaaggcat taccttccgt gatattagtc ctttgatggc tgatggaaat
    13321 gcttatagct acgctgttcg tgaaatcgtt cagtatgcta ctgacaagaa agtcgacatg
    13381 atcgtgggac ctgaagctcg tggatttatc gtgggttgtc cagttgcctt tgagttggga
    13441 attggttttg cgcctgttcg taagccaggt aaattgccac gcgaagttat ttctgctgac
    13501 tatgaaaaag agtacggtgt cgataccttg actatgcacg cggatgccat taagccaggt
    13561 caacgtgttc ttattgtaga tgaccttttg gcgacaggtg gaactgttaa ggcaactatc
    13621 gagatgattg aaaaacttgg tggtgttatg gcaggttgtg ccttccttgt tgaattggat
    13681 gaattgaacg gccgtgaaaa aattggtgac tacgactaca aagttcttat gcattattaa
    13741 tgaaaacagt ccctagggct gttttctcta cactaggata taaaaataga ctataactag
    13801 ttagagaaaa actataattg aaaactatat cttcttacag tataataaaa ggactaagtg
    13861 tttgagattt gtcttcaaac atatgcaatt attcctgaaa gagtacagtt aggagagggt
    13921 tatgccgatt cgaattgata aaaaattgcc agctgttgag attttacgga cagagaatat
    13981 ctttgtcatg gatgatcaac gtgctgccca ccaagatatc cgtcctttga agattttaat
    14041 tttaaatctc atgccacaga aaatggtcac agagacccag ttgttgcgcc acttggctaa
    14101 tacaccccta caactggata ttgattttct ctatatggag agccaccgtt ctaaaacaac
    14161 tcgttcagag cacatggaga ccttctataa aacttttcct gaagtcaagg atgagtattt
    14221 tgatgggatg atcatcacgg gtgctccagt tgagcattta ccatttgagg aagtggacta
    14281 ttgggaggaa tttagacaga tgcttgagtg gtctaagact catgtctatt cgacccttca
    14341 tatctgttgg ggggctcagg ctgggcttta tctgcgctat ggtgtagaaa aataccagat
    14401 ggacagtaag ctatcaggta tttatcctca ggacacccta aaagagggtc accttctatt
    14461 tagaggcttt gatgatagct atgtatcccc tcattcacgg cacacggaga tttctaagga
    14521 agaggtctta aacaagacca atctcgagat tttatcagaa ggacctcagg ttggggtttc
    14581 tattttggcc agtcgtgatt tacgagaaat ttatagtttt ggtcatttgg agtatgaccg
    14641 tgataccttg gcaaaagagt attttcgaga tcgtgatgca ggtttcgacc cacatattcc
    14701 agaaaattac tttaaagatg atgatgttaa tcaggtacct tgtctttgtt ggtcttcatc
    14761 tgcagccctc tttttcagta attgggtaaa ccatgcggtc tatcaggaga cgccttttga
    14821 ttggagaaag atagaagatg atgcatctgc atatgggtat ttataagagg aattatgaca
    14881 tatttagacg cttttaaatc aggtatcttg gttttaccga gtgccctgct cttgcatttt
    14941 aaggaactct ttccttctag cgacgatttt ctggtttggc aatttttcta tttgcaaaat
    15001 acgacaggct tagaagaaat gtcgccaagc cagattgctg aaaggattgg caaggaaatt
    15061 tcggatgtca accagtccat ttctaatctg acggaaaggg gactgctcca gtatcgtact
    15121 atcgaattaa atggcgaaat tgaattgctc tttgatgcta gtttggcctt ggaacgtttg
    15181 gatgacctgt ttggagcagt tcattcaagt tcagaccagc tgacacctca aaaccagctc
    15241 aaggatttgg tggaaacctt ccagcaggag ttgggacgat tgttgacgcc ttttgagatt
    15301 gaggatttga ccaagacact aaaggaagat ggaaccagtg ctgacttgat taaggaggct
    15361 cttcgtgaag ctgttttgaa tggaaaacca aactggaagt acattcaggc gattttgaga
    15421 aactggcgcc atgaaggaat caagagtgtg gctcaaattg aggccaagag agcagaaaga
    15481 gaagcaagca atcctcagtt gacacaggta tctgcagatt tcataaatgc catggatctc
    15541 tggaaggatt aatccatgca agtaggcttg aaatccgagt aagatttgca agctgtgtat
    15601 aattgtgata gaataaatag aaaataaatt gaaaaaagag gtatgtgaaa tgtcacgtaa
    15661 accatttatc gctggtaact ggaaaatgaa caaaaatcca gaagaagcta aagcattcgt
    15721 tgaagcagtt gcatcaaaac ttccttcatc agatctggtt gaagcaggta tcgctgctcc
    15781 agctcttgat ttgacaactg ttcttgctgt tgcaaaaggc tcaaacctta aagttgctgc
    15841 tcaaaactgc tattttgaaa atgcaggtgc tttcactggt gaaactagcc cacaagtttt
    15901 gaaagaaatc ggtactgact acgttgttat cggtcactca gaacgccgtg actacttcca
    15961 tgaaactgac gaagatatca acaaaaaagc aaaagcaatc tttgcgaacg gtatgcttcc
    16021 aatcatctgt tgtggtgaat cacttgaaac ttacgaagct ggtaaagctg ctgaattcgt
    16081 aggtgctcaa gtatctgctg cattggctgg attgactgct gaacaagttg ctgcctcagt
    16141 tatcgcttat gagccaatct gggctatcgg tactggtaaa tcagcttcac aagacgatgc
    16201 acaaaaaatg tgtaaagttg ttcgtgacgt tgtagctgct gactttggtc aagaagtcgc
    16261 agacaaagtt cgtgttcaat acggtggttc tgttaaacct gaaaatgttg cttcatacat
    16321 ggcttgccca gacgttgacg gtgcccttgt aggtggtgcg tcacttgaag ctgaaagctt
    16381 cttggctttg cttgactttg taaaataatc agtaagtagc aaaagctagg tggaacagca
    16441 ttcagatgtc tgttacattt tttataggag aggaaagatt gaaaacaaaa attggattag
    16501 caagtatctg tttactaggc ttggcaacta gtcatgtcgc tgcaaatgaa actgaagtag
    16561 caaaaacttc gcaggataca acgacagctt caagtagttc agagcaaaat cagtcttcta
    16621 ataaaacgca aacgagcaca gaagtacaga ctaatgctgc tgcccactgg gatggggatt
    16681 attatgtaaa ggatgatggc tctaaagctc aaagtgaatg gatttttgac aactactata
    16741 aggcctggtt ttatattaat tcagatggtc gttactcgca gaatgaatgg catggaaatt
    16801 actacctgaa atcaggtgga tatatggccc aaaacgagtg gatctatgac agtaattaca
    16861 agagttggtt ttatctcaag tcagatgggg cttatgctca tcaagaatgg caattgattg
    16921 gaaataagtg gtactacttc aagaagtggg gttacatggc taaaagccaa tggcaaggaa
    16981 gttatttctt gaatggtcaa ggagctatga tgcaaaatga atggctctat gatccagcct
    17041 attctgctta tttttatcta aaatccgatg gaacttatgc taaccaagag tggcaaaaag
    17101 tgggcggcaa atggtactat ttcaagaagt ggggctatat ggctcggaat gagtggcaag
    17161 gcaactacta tttgactgga agtggtgcta tggcgactga cgaagtgatt atggatggtg
    17221 ctcgctatat ctttgcggcc tctggtgagc tcaaagaaaa gaaagatttg aatgtcggct
    17281 gggttcacag agatggtaaa cgctatttct ttaataatag agaagaacaa gtgggaaccg
    17341 aacatgctaa gaaagtcatt gatattagtg agcacaatgg tcgtatcaat gattggaaaa
    17401 aggttattga tgagaacgag gtggatggtg tcattgttcg tctaggttat agcggtaaag
    17461 aagacaagga attggcgcat aacattaagg agttaaaccg tctgggaatt ccttatggtg
    17521 tctatctcta tacctatgct gaaaatgaga ccgatgctga gaatgacgct aaacagacca
    17581 ttgaacttat aaagaaatac aatatgaacc tgtcttaccc tatctattat gatgttgaga
    17641 actgggaata tgtaaataag agcaagagag ctccaagtga tacagacact tgggttaaaa
    17701 tcatcaacaa gtacatggac acgatgaagc aggcgggtta tcaaaatgtg tatgtctata
    17761 gctatcgtag tttattacag acgcgtttaa aacacccaga tattttaaaa catgtaaact
    17821 gggtagcggc ctatacgaat gctttagaat gggaaaaccc ttattattca ggagaaaaag
    17881 gttggcaata tacctcttct gaatacatga aaggaatcca agggcgcgta gatgtcagcg
    17941 tttggtatta agcgatgatt tgaaagaggg atgtgatagt agcaccctct ttttctttgt
    18001 tttatgatag ttcatcctcg agtaaattca agatcttgct cggaaatgaa gcttatatag
    18061 tagattgaat atagacaaag accttgtgat tggtaaaaca ttttagaaat tcatttacct
    18121 ttcctaatcg acttggtttc atcttatttc aatctattat agtattgggg aatttcttca
    18181 aaccacatca gcttggtcag ttctacctgc gacctcaaaa cttgtgcttt ggtcaagctg
    18241 ggtttagttt cctagtttgc tgatggattt ccattgacta taagcatcca accctctttt
    18301 ttgtcttcta aagaattctt aaattatcag tctattgcaa cttttctcat ataagttctt
    18361 tgtcttgcta ttagttttcc ttagtagtat actaaggtag taatcattaa gaagtggtta
    18421 caaaaaataa tgaatgaggt aaagaaaatg gtagaattga aaaaagaagc agtaaaagac
    18481 gtaacatcat tgacaaaagc agcgccagta gcattggcaa aaacaaagga agtcttgaac
    18541 caagctgttg ctgatttgta tgtagctcac gttgctttgc accaagtgca ctggtatatg
    18601 catggtcgtg gtttccttgt atggcatcca aaaatggatg agtacatgga agctcttgac
    18661 ggtcaattgg atgaaatcag cgaacgcttg attacactcg gtggaagccc attctctaca
    18721 ttgacagagt tccttcaaaa tagtgaaatc gaagaagaag ctagtgaata ccgtaatgtt
    18781 gaagaaagct tggaacgtgt tcttgttatc taccgttact tgtcagaact tttccaaaaa
    18841 ggtttggatg tcactgatga agaaggtgac gatgtgacaa acggtatctt tgcaggcgct
    18901 aaaactgaaa cagataaaac aatttggatg cttgcagccg aacttggaca agcacctggt
    18961 ttgtaagaaa taaggaaaca tagataaatc tgtaggaaat ttcttacaga ttttttctat
    19021 tttgtaagct attccaaacc agtctttttt tgagtttttt gataaaatag tactatcagt
    19081 gaaaaggatg gaagtatgac taagaaaatc gtagctattt gggcccagga tgaagagggt
    19141 gtgattggta aggaaaatcg tctgccttgg catttgccag cagaattgca gcactttaaa
    19201 gaaacaactc tgaatcatgc tatcttgatg gggcgtgtga cctttgatgg gatggggcgt
    19261 cgcttgcttc caaaacggga aaccttgatt ttgacgcgta atccggaaga aaagatagat
    19321 ggggttgcta cttttcagga cgtccagtct gttcttgact ggtatcaggc tcaagaaaag
    19381 aatctctaca ttattggtgg gaagcaaatt tttcaggctt ttgaacctta ccttgatgaa
    19441 gtgattgtca ctcacattca tgctcgtgtg gaaggagata cctatttccc tgaagaactt
    19501 gacttgtctc tttttgagac agtttcaagc aaattttacg ccaaagatga gaagaatcct
    19561 tatgatttta ccatccaata ccgcaagaga aaggaactct aatggaacgg agtttatttg
    19621 gtctattcac ggcttttctg tgtttcatct gctttctggc aggagcacaa gcttttcgta
    19681 aaaagcgtta cgggctttct atcctccttt ggttaaatgc ctttaccaat ctggtcaata
    19741 gtattcatgc tttttacatg accttatttt agatagaatg acagtataga atggaaggaa
    19801 atcatgtcta caaatagaaa aaatgatatg atggtttatt gctcattttg tggcaaaaac
    19861 caagaagaag tacaaaaaat aattgctggc aacaatgctt ttatttgtaa tgaatgcgtg
    19921 gagttagctc aggaaatcat tcgagaagaa ttggttgagg aagtcttggc agacttgtct
    19981 gaggtgccaa aaccaattga actcctccat atcttgaacc actatgtaat tggtcaagat
    20041 cgtgccaagc gtgccttggc agtggcggtt tataaccact acaaacgcat caatttccac
    20101 gatacacgcg aagagtcaga agatgtagat ttgcagaagt caaacatttt gatgattggc
    20161 ccaactggtt cagggaaaac tttccttgcc cagaccttgg ctaagagctt gaatgtgcct
    20221 tttgctattg cggatgcgac agctctgacg gaggctggtt atgtgggtga ggatgtggaa
    20281 aatatcctcc tcaaactctt gcaggttgct gactttaaca tcgaacgtgc agagcgtggc
    20341 attatctatg tggatgaaat tgacaagatt gccaagaaga gtgagaatgt gtctatcaca
    20401 cgtgatgttt ctggtgaagg ggtgcaacaa gcccttctca agattatcga gggaactgtt
    20461 gctagcgtgc cgcctcaagg tggacgcaaa catccacaac aagagatgat tcaagtggat
    20521 acaaaaaata tcctcttcat cgtgggtggt gcttttgatg gtattgaaga aattgtcaaa
    20581 caacgtctgg gtgaaaaagt catcggattt ggtcaaaaca ataaggcgat tgatgaaaac
    20641 agctcatata tgcaagaaat catcgctgaa gacattcaaa aatttggtat tatccctgag
    20701 ttgattggac gcttgcctgt ttttgcggct cttgagcaat tgaccgttga tgacttggtt
    20761 cgcatcttga aagagccaag aaatgccttg gtgaaacaat accaaacctt gctttcttat
    20821 gatgatgttg agttggaatt tgacgacgaa gcccttcaag agattgctaa taaagcaatc
    20881 gaacggaaga caggggcgcg tggacttcgc tccatcatcg aagaaaccat gctagatgtt
    20941 atgtttgagg tgccgagtca ggaaaatgtg aaattggttc gcatcactaa agaaactgtc
    21001 gatggaacgg ataaaccgat cctagaaaca gcctagaggt gactatggaa cttaatatac
    21061 acaatgctga aatcttgctc agtgcagcta ataagtccca ctatccgcag gatgaactgc
    21121 cagagattgc cctagcaggg cgttcaaatg ttggtaaatc cagctttatc aacactatgt
    21181 tgaaccgtaa gaatctcgcc cgtacatcag gaaaacctgg taaaacccag ctcctgaact
    21241 tttttaacat tgatgacaag atgcgctttg tggatgtgcc tggttatggc tatgctcgtg
    21301 tttctaaaaa ggaacgtgaa aagtgggggt gcatgattga ggagtactta acgactcggg
    21361 aaaatctccg tgcggttgtc agtctagttg accttcgtca tgacccgtca gcagatgatg
    21421 tgcagatgta cgaatttctc aagtattatg agattccagt catcattgtg gcgaccaagg
    21481 cggacaagat tcctcgtggt aaatggaaca agcatgaatc agcaatcaaa aagaaattaa
    21541 actttgaccc aagtgacgat ttcatcctct tttcatctgt cagcaaggca gggatggatg
    21601 aggcttggga tgcaatctta gaaaaattgt gaggaaaaga aaatggcaaa aacaattcat
    21661 acagataagg ccccaaaggc tatcggaccc tatgttcaag gaaaaatcgt tggcaacctt
    21721 ttgtttgcta gcggtcaagt tcccctatcc cctgaaactg gggaaattgt aggagagaat
    21781 atccaagaac agacagagca agtcttgaaa aacatcggtg ctattttggc agaagcagga
    21841 acagactttg accatgttgt caaaacaact tgcttcttga gcgatatgaa cgactttgtt
    21901 ccttttaatg aggtttacca aacggccttc aaagaggaat tcccagctcg ttcagctgtg
    21961 gaggtagctc gtcttcctcg tgatgtaaaa gtcgaaattg aagtcatcgc agagattgga
    22021 taagctagtt gaagtttggt gttgccaaac ttcttttgat ataaggagaa aaagatgaca
    22081 aagaaacaac ttcacttggt gattgtgaca gggatgagtg gcgcagggaa aactgtagcc
    22141 attcagtcct tcgaggatct aggttatttc accattgata atatgccgcc agctctcttg
    22201 cctaagtttt tgcagctggt tgaaattaag gaagacaatc ctaagttggc cttggtagtg
    22261 gatatgcgta gccgttcttt cttttcagag attcaagctg ttttggatga gttggaaaat
    22321 caagatggtt tggatttcaa aatcctcttt ttggatgcgg ctgataagga attggtcgct
    22381 cgttacaagg aaaccagacg gagtcaccca ctagcagcag acggtcgtat tttagatgga
    22441 atcaagttgg aacgtgaact cttggcacct ttgaaaaata tgagccaaaa tgtggtggat
    22501 acgactgaac tcactccacg tgagctgcgc aaaacccttg cagagcagtt ttcagaccaa
    22561 gaacaagccc agtctttccg tatcgaagtc atgtctttcg gatttaagta tggaatcccg
    22621 attgatgcgg acttggtctt tgatgtccgt ttcttgccaa atccctatta tctaccagaa
    22681 ctgagaaacc aaacgggtgt ggatgaacct gtttatgatt atgtcatgaa ccatcctgag
    22741 tcagaagact tttatcaaca tttattggcc ttgattgagc cgattctgcc aagttaccaa
    22801 aaggaaggta agtccgtttt gaccattgcc atgggatgta cgggtggaca acaccgtagt
    22861 gtggcatttg ctaaacgctt ggcgcaggac ttatccaaga attggtctgt taatgaaggg
    22921 catcgcgaca aagaccgcag aaaggaaacg gtaaaccgtt catgagaaaa ccaaagataa
    22981 cggtgattgg tggagggact ggaattcccg tcattctaaa aagtctgcgg gaaaaagatg
    23041 tggaaatcgc agctatcgtg acggtggcag atgatggtgg ttcttcaggt gaactccgaa
    23101 aaaatatgca acagttgaca ccgccaggtg atcttcgtaa tgtccttgtg gccatgtcgg
    23161 atatgcctaa gttttatgag aaggtctttc agtatcggtt ctctgaggat gccggagcct
    23221 ttgctggcca tccattggga aatctcatca ttgctggctt gtcagaaatg cagggttcaa
    23281 cctataatgc catgcagtta ttgagcaaat ttttccatac aacagggaaa atttatcctt
    23341 ccagtgacca tcctttgacc cttcatgcag tctttcagga tgggacagaa gtggttggag
    23401 agagtcatat tgtagaccat cgaggcataa ttgacaatgt ctatgtgact aatgctctaa
    23461 acgatgatac gcctctggcc agccgtcgag tagtgcagac catccttgaa agtgacatga
    23521 ttgtcctagg gccaggttcc ctctttacct ctattttgcc caatatcgtg attaaggaaa
    23581 ttgggcgggc tcttttggaa accaaggcag aaattgccta tgtctgcaat attatgaccc
    23641 aacgtggaga gacggaacac tttacagata gcgaccacgt ggaagtcttg catcgtcacc
    23701 ttggtcgccc ttttatcgac actgtcttgg tgaatattga aaaagtgcct cagaaataca
    23761 tgaattccaa ccgttttgat gaatacttgg tgcaagtgga acacgatttt gtaggtcttt
    23821 gtaagcaagt ttcgcgcgtg atttcatcta acttccttcg tctggaaaat ggcggtgcct
    23881 tccacgatgg agatttgatt gtggacgagt tgatgcgcat tatacaggtg aaaaaatgag
    23941 tttcacagta gcagtaaaag aagaaatcct gggccaacac catctgagcc ggcatgaatt
    24001 atctgccatt atcaaaatgt ctggtagcat cggtctctcg acttcgggct tgactttgtc
    24061 agttgtgaca gaaaatgcca aactggcccg tcacctctat gagtcctttc tccatttcta
    24121 tgaaatcaaa tctgaaattc gtcaccacca acggagcaat cttcgcaaga atcgcgtcta
    24181 taccgttttt acagatgaaa aggtgcagga tttgttaagt gatttgcact tggcagactc
    24241 tttctttggc ttggaaacag gtattgatga ggcgatttta tcggatgagg aagcaggtcg
    24301 tgcctatctc tgtggcgctt tcttggcaaa tgggagcatt cgtgaccctg agtcaggcaa
    24361 gtaccagttg gaaatcagtt ctgtttatct ggaccacgcg caaggaattg cctcccttct
    24421 ccaacagttt ttactggatg ccaaggtgct tgagcgcaag aagggggctg tgacctatct
    24481 ccagcgagca gaagacatta tggacttctt gatagtaatc ggagccatgc aggcacgtga
    24541 tgattttgag cgggttaaga ttttgcgaga aactcgtaac gacctcaatc gggctaataa
    24601 tgccgagaca gctaatatcg ctcggacagt ttctgccagc atgaagacca ttaacaatat
    24661 cagtaaaatc aaagatatca tgggcttaga aaatttgcca gtagatttgc aggaagtggc
    24721 gcaactgagg attcagcacc cagactactc tatccagcag ttagcagata gcctcagcac
    24781 ccctctgacc aaaagtggtg tcaatcacag actcagaaaa atcaataaga tagccgatga
    24841 attataaaac cacgaatcct atgtgactcg tggttctttt ttataaacta gtagagtgtt
    24901 ttggttgtac tttttgttca gggtcaatgt agttgatagc gttgttgaca gcagttggag
    24961 cttctccgag gcctgtcgca atcagatcaa tttttccgtc atagtagcag cagtcaccga
    25021 tagcatagat acctgcttgg ctggattcct gtttgctgtt gacgataatc ttgtgacggt
    25081 tgaggtcgag cccccagttt ttaaggttac cgacagaaga tttgaaacca tagttgacaa
    25141 agaggtggtc taggtcaatg gtttcagttt catcagattt gacttttgtg atttcaagtt
    25201 tatcaagtgt ttttccattt ccaaggagtt ggctaggggc gaatggtgtc ttgatggtta
    25261 cagatgattc ttgcaaggct tgaacactgt gttccaaggc acggaaatta tctctgcggt
    25321 gaacaagggt agttggtgcg attttttcaa aagccaaagc ccaatccaca gccgagtctc
    25381 ccccaccaag aatcgtcact ttcttaccag cgtattgctg aatgttagaa acgtggtagt
    25441 ggatattttc atagccctca accccttcaa gttccagcgg acgtggtttg aaggcaccgc
    25501 cacccatagc gatgatgact gttttagtca agtgacttcc tttagaagtt gtgatggcaa
    25561 attcttcttc ttgtttgtca atctcaagaa ccgtttcatt gagatgaata ggggtatcaa
    25621 atccatttag ctgttcaatc aagcggttag tcaactcttc tccagtcagg tttgggaagc
    25681 ctggtacgtc taggatttcc ttttcagggt agagaatagc aggttgtcca cctagctggg
    25741 gaagagagtc gatgatttga accttggctt ggcgtaggtg ggcataaaag gctgcaaaaa
    25801 gcccgacagg accaccaccc acaatggtaa tatcatagag ttgagacata gtttctcctt
    25861 tgttttttct agtcagttta ttttatcata tttttgttca atgtaaactg gactaggata
    25921 gggaaaaaaa tgccagaaaa tggtataata ggacgaaagt gttttgatag ggaggatatc
    25981 agggatgaat tttcaacaat tatccaatct gcaatattgg accagtttgt ttgcaagtcc
    26041 atggacgata gctatcaatc tgattgatat tttgattgtt gcttatattt tataccattt
    26101 tacaaaagct attgcaggaa ccaagattat gattttggta cgtggagttt tggtgtttat
    26161 tttagctcaa atccttgcaa atatgattgg tttgactacg atttcttggt taatcaatca
    26221 aattattact tatggggtta ttgcggcggt tgttatcttc tctccagaga ttcggactgg
    26281 tttggaacgt ttgggaagag cgacagattt cttttccaat gcccctatta gtgctgagga
    26341 acagatgatt cgtgcctttg ttaagtctgt tgaatacatg agtcctcgta aaatcggggc
    26401 cttggttgct attcagcgtg tacgtacctt gcaggagtat atttcgacag gaattccctt
    26461 ggatgctaag atttctgcag aacttctcat taacattttt attcccaaca ctcccctaca
    26521 tgatggtgcg gtgattatca aagaagaacg tatcgctgtg acgtctgcct atctgccctt
    26581 gacaaaaaac acagggattt ccaaggaatt tgggaccaga caccgggcgg ctatcggttt
    26641 atcagaagtc tcagatgcct tgacttttgt tgtatcagag gaaacgggag gaatttcgat
    26701 aacctataat ggaaggttta agcacaacct aacacttgat gaatttgaaa cagaattacg
    26761 tgaaatctta cttccaaaag aggaagtggg tcttagtttt aaagaacgat tgctaggagg
    26821 atggaaacat gaaaaaaaat agtttatata tcatatcctc actctttttt gcttgtgtct
    26881 tatttgtcta tgctacggcg acgaattttc aaaacagtac cagtgctagg caggtaaaaa
    26941 cggaaaccta tactaataca gtaacaaatg tccctattga catacgctat aatagtgata
    27001 agtattttat tagcggtttt gcttcagaag tatcagtggt cttgactggt gcaaatcgcc
    27061 tatcgctagc tagtgaaatg caagaaagta cacgtaaatt caaggttact gctgacctaa
    27121 cagatgccgg tgttggaacg attgaagttc ctttgagcat tgaagattta cccaatgggc
    27181 tgaccgctgt ggcgactccg caaaaaatta cagtcaagat tggtaagaag gctcagaagg
    27241 ataaggtaaa gattgtacca gagattgacc ctagtcaaat tgatagtcgg gtacaaattg
    27301 aaaatgtcat ggtgtcagat aaagaagtgt ctattacgag tgaccaagag acattggata
    27361 gaattgataa gattatcgct gtcttgccaa ctagcgaacg cataacaggt aattacagtg
    27421 gttcagtacc tttgcaggca atcgaccgca atggtgttgt cttaccggca gttatcactc
    27481 cgtttgatac aataatgaag gtgactacaa aaccagtagc accaagttca agcacatcaa
    27541 attcaagtac aagcagttca tcggagacat cttcgtcaac gaaagcaact agttcaaaaa
    27601 cgaattaaaa atagaaaagg attttataac aatgggtaaa tattttggga ctgatggagt
    27661 ccgtggagaa gctaacctag aactaacacc agaattagcc tttaaactag gacgttttgg
    27721 aggctatgtt cttagtcaac atgaaacgga agcgccgaaa gtctttgtag gacgtgacac
    27781 acgtatttca ggggaaatgc tggaatcggc cttggtggca ggtctccttt cagtagggat
    27841 tcacgtatac aaacttggtg tccttgcaac accagcagta gcttacttgg ttgaaactga
    27901 aggagcaagt gccggtgtca tgatttctgc tagccacaac ccagcccttg ataacggaat
    27961 caagttcttt ggcggtgatg gcttcaaact agatgatgaa aaagaagcag aaattgaagc
    28021 cttgctagat gctgaggaag acactcttcc tcgtccaagt gcagaaggct taggaatctt
    28081 ggtagattat ccagaaggct tgcgtaagta tgaaggatac cttgtttcaa ctggaactcc
    28141 tcttgatgga atgaaggttg ccttggatac agctaatgga gcagcttcta ccagtgcccg
    28201 tcaaatcttt gcagaccttg gtgcccaatt gacggttatc ggggaaacac cagacggtct
    28261 taacatcaac cttaatgttg gttcaacaca tccagaagcc cttcaagaag tggtcaaaga
    28321 aagtgggtca gctattggtt tggcctttga tggagacagt gaccgcttga ttgctgttga
    28381 tgagaatggt gacatcgtcg atggtgacaa gattatgtac atcatcggaa aatacctttc
    28441 tgaaaaagga caattggctc aaaatacaat tgtgacaact gttatgtcta accttggttt
    28501 ccacaaggcc ttgaatcgcg aaggtattaa caaggcagtt actgcagttg gtgaccgcta
    28561 cgttgttgaa gaaatgagaa aatcaggcta caaccttggt ggtgaacagt ctggtcacgt
    28621 tatcttgatg gattacaata ccacaggtga tggtcaatta tcagcagttc aattgactaa
    28681 aatcatgaag gaaactggta agagcttatc agagttggcg gcagaagtaa cgatttatcc
    28741 acaaaaatta gttaatatcc gagtggaaaa cgtcatgaag gaaaaggcca tggaagtgcc
    28801 agctatcaag gccatcatcg agaagatgga agaagaaatg gcggggaacg gccgtatcct
    28861 tgttcgtcca agtggaacag agcccctctt gcgtgttatg gcagaagcgc ctacaacaga
    28921 agaagtagac tactatgttg ataccatcac agatgtagtt cgtgctgaaa ttgggattga
    28981 ttaaatccta gaaaactaga tgaaaataaa aaattatggt acaatagctt ataatattgt
    29041 agccgatgga gaaagacatg aatcttaaac gtgaacaaga atttgttagt cagtatcatt
    29101 ttgatgcgcg taattttgaa tgggaaaatg aaaatggagc tcctgaaacc aaggtggatg
    29161 tgaatttcca attgctccaa catgaccaag aaaatcaagt gacttccttg attgtcatct
    29221 tgagctttat gattgtattt gataagtttg tcattagtgg aacaatctca caagtaaacc
    29281 atatcgatgg ccgtattgtc aatgaaccaa atgaattgaa ccaagaagag gtggaaacct
    29341 tggctcgtcc atgtttgaac atgctcaatc gtttgactta cgaagtgact gaaattgcat
    29401 tagacttacc aggaattaat ttggagttct aatatgaaat tagctgtttt cacagattcc
    29461 tctgcttatc tcagtgcaga gaccttgcaa agagaagact tgtttgtctt ggatattcct
    29521 gtcaatattg atggtgagga atatgtcgaa ggcatcaatc tgtctgctga ggaattttac
    29581 caaaaaatgg ctcaggcttc tgaattgcct aagaccagtc aaccaagtat tgccaagtta
    29641 gatgaaatct taacttcgct caaagaacaa ggctatacac atgccttggg gcttttccta
    29701 tcttctggaa tttcaggttt ttaccaaaat atccagtata tggtcgatga ctatgagggc
    29761 ttaaccattg ctttcccaga cactttgatt acaagtgctc ccctaggcat catggttgaa
    29821 agcgtcttta attggcgtga tcagggcgat gattttgcca gcattcagga taagctagcc
    29881 attcaaatca gccgtacgtc agcctttatc atggtagatg acttggatca tttggtaaaa
    29941 ggtggacgtc tttcaaatgg ggctgccatt ttgggcaatt tgcttagcat taagccaatc
    30001 ctttatttta acgatcaagg tgtgattgaa gtttacgaaa aagttcgtac tgaaaagaag
    30061 gccaccaagc gcttaattga aattatcaag gaaacaacgg cttcaggtca ataccgggtc
    30121 attgtcattc atgggaatgc tcctgaaaag gctgaagaat tgcgtcagca tttgcttgat
    30181 tttggcttgg gttcggatgt ttcacttgct acatttggta gtgtcattgg aacgcaccta
    30241 ggagcaggaa gtattgctct gggttatatt ccagtgattt agttggcgct tctaggctag
    30301 ttaagatgcc ttgtatctta gcaattgaac acggactacc tgcttcttga aaaaagatgc
    30361 ctgtcttgcc tttcgtggaa agtcagtgcc attccctatt tttcaggggc agctaaggtc
    30421 ctttgtatct tgataattga acacgcctgg aaccctgtgt gaaaaagata gttcttccaa
    30481 gaagtagaca cttcttgatt ggaattccta ttttcacttt gtgttcttac ggactttgta
    30541 tcttagacag gagtagagat gagtattcga gtaattattg ccggttttaa gggaaagatg
    30601 ggccaggctg cttgtcagat ggtattgact gatccagact tggacttggt agcagttttg
    30661 gatccttttg agtctgagtc agaatggcag ggtattcctg ttttcaagga taaggctgat
    30721 ttagcttgtt ttgaagcgga tgtctgggta gattttacta ctccagctgt tgcctacgaa
    30781 aatacacgtt ttgctcttga aaatggcttt gctccagtag ttggaacgac tggtttcacg
    30841 agtgaagaaa ttgcagagct aaaagaattt tctcgtaccc aagacttggg tggcctgatt
    30901 gcccctaact ttgccttggg tgctgtctta ctcatgcaat ttgcgacgca ggctgccaaa
    30961 tatttcccaa atgtggagat tattgagctc catcatgaca agaaaaagga tgctccgagt
    31021 ggaacagcca ttaaaacagc tgagttgatg gcagagattc gagagtcaat tcagcaaggt
    31081 gcagcagatg aggaagagct gattgctggt gctcgtggtg ctgactttga tggtatgcgc
    31141 atccactcag ttcgtttgcc aggtttggta gcccatcagg aagtcatctt tggcaatcaa
    31201 ggagaaggat tgaccctccg tcatgactcc tatgatcgca tctccttcat gacaggagtc
    31261 aatttgggaa ttaaagaagt tgtcaagcgt catgagcttg tctatggatt agaacactta
    31321 ttatgagatt aatgcaaatg ccttctgaat ttcagaaggc tttaccagta ttagaaaaaa
    31381 ttaaagaagc aggctttgag gcttattttg ttgggggctc tgttcgagat gcccttctcc
    31441 atagccctat ccacgatgtg gatattgcga cgtcttctta tccagaagag accaagcaga
    31501 tttttccgcg aacagccgat atcggaatcg agcatggaac cgtcttggtc ttagatgggg
    31561 atgaggagta tgaggtaaca acctttcgga cagaggatgt ctatgtggac tatcgcagac
    31621 ccagtgcggt ttcctttgtg cgctcgctag aagaagacct caaacgccgt gatttcacag
    31681 tcaacgcctt tgccttggat gagacaggag aaatcgttga cttgttccat ggtttagaag
    31741 atttggaaaa gcaagtcttg cgagcagttg gagtggctag tgagcgtttc aacgaagatg
    31801 ctttacggat tatgcgtggt ttccgttttc aggctagtct tggttttgca cttgaaccag
    31861 aaacatttaa agctatgaag accttgacgc cgcttttgga gaacatttct gtagagcgta
    31921 ccttcgtcga gtttgataaa ctcttgctgg ctccattttg gagaaggggg ttggcttcca
    31981 tgattgagag tcaagcttat gactatctcc ctgatatggc atctagccag gacaagctca
    32041 acagactgtt tgatttggag actgatttta cttttgaatc ctctgaacaa gcctgggcgg
    32101 ctttactatg ggctttggag attgaaaatg cgcagtcatt tttgaaatct tggaagacct
    32161 cacgccagtt tgccaagcaa gttcaggatt tgctgattat tttggctctg cgtgaaaatg
    32221 gagaattgag caagcgagat tgttatcgct ttgacataga tttgctttta caggctgaaa
    32281 atcttcgtca agctcaagga aaagaagtca acccacaagc catcacagaa aaataccaaa
    32341 gcttgactat ccatgacaag aaagagattc agattaatgg cggtattttg atcaaggaat
    32401 atggctatca gccaggccca gacttgggag agattttaac agagattgag tttgccattg
    32461 tcgatggaga attggagaat aatcgtgaag ccatccatgc ttacctgagg gagaaaaaat
    32521 gagtgatttt atcgttgaaa aactaagtaa atctgttggt gacaagaccg tttttaggga
    32581 tatttccttt attatccatg acttagacag aattggttta atcggtgtca atgggactgg
    32641 caagaccacc cttttggacg tcctttctgg tgtttctggc tttgatgggg atgtcagtcc
    32701 tttttcagct aaaaatgatt accagattgg ttacttgact caggatcctg attttgatga
    32761 tagaaagaca gttttggata cgattctatc tagtgaactc aaggaaatcc agctcattcg
    32821 tgagtatgaa ttgattatgc tcgactatag cgaggacaag caggcgcgtt tggaacgtgt
    32881 catggcagag atggactctc tccaagcttg ggaaatcgag agtcaggtca agaccgttct
    32941 tagcaaattg ggcattcaag acttatctac tcctgttggg gaattgtcag gtggtctgag
    33001 aagacgggta cagttggcac aagtcttact tggcaaccac gacctcttgc ttttggatga
    33061 gccgaccaac catctggata ttgcgattat tgagtggctg accctctttt tgaaaaattc
    33121 taagaagacc gtccttttta tcactcacga tcgttatttc ttagacgctt tgtcaacacg
    33181 gattttcgag ttggagcgag caggcttgac agaatatcag ggcaattacc aggactatgt
    33241 tcgccttaag gcagaacagg acgagcgcga tgcagctcta cttcataaaa aagaacaact
    33301 ctacaaacaa gaactggtct ggatgcgcag acaaccgcag gcacgtgcga ccaagcaaca
    33361 agctcgtatc aatcgtttcc atgatctgaa aaaggaagtt tcaggcagta gtgctgagac
    33421 agacttgact atgaactttg aaaccagtcg gattgggaag aaagtcatcg agtttcaggc
    33481 tgtttccttt gcctatgaaa ataagcccat tttgcaagat tttaatctct tagttcaggc
    33541 taaagaccgt attggaattg ttggggacaa tggtgttgga aaatcaaccc tacttaacct
    33601 gattgcagga agtcttgagc cgacagcagg acaagttgtg attggggaaa ctgttcgcat
    33661 cgcctatttc tctcaacaaa ttgagggttt ggatgaaagc aagcgtgtga tcaattacct
    33721 gcaggaagtg gcagaggagg tcaagaccag tggtggttct acgacttcca tcgctgagtt
    33781 gctggagcaa ttcctcttcc cacgttcgac gcatgggacc ttgattgaga aattgtcagg
    33841 gggtgagaaa aaacgtcttt atctcctcaa actgcttttg gaaaaaccaa atgttcttct
    33901 tttagacgag ccaaccaatg acctagatat tgcaactttg acagtcttag agaatttctt
    33961 gcaaggtttt gcaggtcccg ttttaacagt cagtcacgac cgctatttct tggataaggt
    34021 agcgaccaag attctcgctt ttgaggatgg caagattcgt cctttctttg gtcattacac
    34081 cgactatctt gatgaaaaag cttttgaaac agatatggcc aatcaagtgc aaaaggccga
    34141 aaaggaaaaa gtggtcaagg ttcgagaaga caagaaacgc atgacctacc aagaaaagca
    34201 ggagtgggca agtattgaag gtgatattga aaccttggaa aaacgtatcg ctgctattga
    34261 agaggaaatg caggctaacg gctctgactt tggtaagctg gctactctcc aaaaagaatt
    34321 ggatgagaaa aatgaagcac tccttgaaaa atacgaacgc tatgagtatc tcagtgaatt
    34381 tgatagttaa tactattcga aaatcaaagt gtaaactatg tcggcttcac attgccgact
    34441 caagtacagc ctgtggccgg cttcctagtt tgcactttga tttttattga gtataaaaga
    34501 atagaaaaat cccatctcat gaacggattt ctctattctt ttttggtttc ttgatgaaag
    34561 atattttgcc aggtttcgtg gcgacgccag atactggtat ggatgatacc atctaactca
    34621 tagcagatga gtttggtttt ttgactgatg gaagtaattt gaatgtcctt gatagcagaa
    34681 tttaactctt ttttggtctt ataagcctct ttatccatct gctctccatc ttggcgaata
    34741 tagacaaaat catcagtcaa gagttcttct agttggtttc cttggtcaat caattgttca
    34801 cgcataagca attttttata gacattgtct aaaatttcat cctcagggat aggtgctggt
    34861 tcgatatgga catcggtatc aaagacgcca aaacgattct ccagcataga ctcgacctga
    34921 tccgcgattt catggctttc aaaaacagac aagtcaggat tcatctctag tgtaatatcc
    34981 aggtagatgt tgctaccgta ggtgcgacct ctttgcgatt tgaccttgct gattttggga
    35041 atttccatga tagccttttg gtagtcctcg agcaggcggt cgtcaaagcc atctgaaaga
    35101 ctaaaggaag actcgatgaa gatatcatag gcagtcttca agataaagaa agtgatgatg
    35161 atagcaacca gtttatccac aatcggataa ttgaaactac tagctaggat ggcaatggcg
    35221 gttccaagtg aggtaacagc gtcagaaaga ttgtccttag cagctgcttt cagcgccttg
    35281 gagttggatt tcttactgag gcgagtattg tagagataga ccacaaacat aatcgctgca
    35341 gaaatgattc ctagagttgc accaagagga tcaatgaccg tttcttcccg actgagaatc
    35401 ttttgaatgg tatctcttag aacatcgaaa ccgacataga acatgatgat agaagtgatc
    35461 aagcttgcca aatcttcaat cttccaatga ccaaaacggt ggtcacggtc tgcaggctgg
    35521 cgcgccatcc gaatcccgat taagagggcc acatttccaa tgatgtccga tacgttatta
    35581 aaaccatcgg ccaccaaact ggatgaatga aggagatgac cagttgctaa tttggctgca
    35641 gacaagatca aataggtcga aatactgata atggctccac gctcagctaa cttgagattt
    35701 gagatagatt gcttcattca acttcctttc tagtcacata gcattctacc attatactgg
    35761 ttttcaagga aaaattcaaa taaggcagtt tttactcttt gaaaactccc caaaatttgg
    35821 tataatagta ctactcaagg gagtagctgg cagaaacctg tgatagtgtc gtcattccga
    35881 attttatgct gaaaagtatg ctttccggcc ctatcttaaa cagcgagact tgttatgatt
    35941 aacaggtctc tttttgtttg tcgtgaaaag atatgacaga aagagagtct gttttgcaca
    36001 caatgtcaag gaggagacac atgtcaaaag aacaaaaacg ccaagcgttt tatactcaga
    36061 gccctgaaga ggtcttgcag gctgtggatg cgaccgagca aggtttgtcg tcaagtgagg
    36121 cggaaaagcg ccttgtcgaa tttgggcaca atgaactcga agaaggcgag aaacgatcaa
    36181 tcttggtcaa attcatcgag caatttaagg atttgatgat tatcatccta gttgcggcag
    36241 caatcttgtc agtcgtgact tctggtgggg aagatatcgc agatgccatt atcatcctag
    36301 ctgtggttat catcaacgct gcctttggtg tttaccaaga aggaaaagct gaagaagcta
    36361 ttgaagccct caaatccatg tctagtccag ttgcccgcgt tcttcgtgat ggacacatgg
    36421 cagagattga ctctaaagaa ttggtaccag gcgatatcgt tgcccttgaa gcaggtgacg
    36481 tggtaccagc ggacctacgt ttgatagaag ccaactctct taaaattgaa gaagcagcct
    36541 tgacaggtga atctgtacca gtcgaaaaag acttgtcagt cgagcttgcg acagatgctg
    36601 gtattggtga ccgtgtcaac atggccttcc aaaactcaaa cgtaacctat ggtcgtggga
    36661 tgggtgttgt tgtcaataca ggtatgtaca ctgaagttgg tcatattgct ggtatgcttc
    36721 aagatgcgga tgagactgat acaccactca aacaaaactt gaacaacctt tctaaggtct
    36781 tgacctatgc tatcttggcc attgcccttg ttacttttgt agtgggtgtc ttcattcaag
    36841 ggaaaaatcc acttggtgag ttgttgactt ctgttgccct tgccgttgca gccattccag
    36901 aaggacttcc tgctatcgtt accatcgttc tttctcttgg tactcaagtt ttggccaaac
    36961 gacattccat cgttcgtaag ttgccagcag ttgaaacact tggttcaact gaaatcatcg
    37021 cttctgataa gactggtacg ctgactatga acaagatgac agtcgaaaaa gtcttctacg
    37081 atgcggttct acatgactca gctgatgata ttgaactagg tcttgaaatg ccactacttc
    37141 gttcagttgt cttggccaat gatacgaaaa tcgatgtgga aggtaacttg attggtgacc
    37201 caaccgaaac agcctttatc caatatgcct tggacaaggg ctatgatgtc aaaggtttct
    37261 tagagaaata tcctcgtgta gctgaattgc catttgactc tgaccgtaag ctcatgtcaa
    37321 cagttcaccc attgccagat ggtcgtttcc ttgtagcagt caagggtgcg ccagaccaac
    37381 tcttaaaacg ttgtcttctt cgtgataagg ctggggatat tgctccgatt gatgagaagg
    37441 ttacaaatct cattcataca aacaattctg aaatggctca tcaagccttg cgtgtccttg
    37501 caggtgctta taagattatc gatagtattc cagaaaatct cacttctgaa gagcttgaaa
    37561 atgatttaat ttttactggt ttgattggga tgattgaccc tgaacgtcct gaagccgctg
    37621 aggctgttcg tgtggctaag gaagcgggaa tccgtccaat tatgattaca ggtgaccacc
    37681 aagacacagc ggaagccatt gccaaacgtt tgggaatcat tgacgcaaac gatacagaag
    37741 gtcacgtttt aactggtgct gaactcaatg aactgtcaga tgaagaattt gaaaaagtcg
    37801 ttggtcaata ctctgtttat gcccgtgtgt ctccagaaca caaggttcgt atcgtcaagg
    37861 cttggcaaaa acaaggtaaa gtcgttgcca tgacaggtga cggtgtcaat gacgcgccag
    37921 ctctgaaaac agccgatatc ggtatcggta tgggaatcac tggtacagag gtttctaagg
    37981 gggcttctga tatgattctt gcagatgata actttgcgac tattatcgtc gcagtggaag
    38041 aaggacgtaa ggtcttctca aacattcaaa agactattca gtacctactt tctgctaata
    38101 ctgctgaagt attaaccatc ttcctatcaa ccttgtttgg ttgggatgtc ttgcagccgg
    38161 ttcatctttt gtggatcaac ttggtaacgg ataccttccc agctatcgct cttggtgttg
    38221 aacctgcgga gcctggtgtc atgaatcata aaccacgtgg acgcaaggca agcttcttct
    38281 caggtggtgt tttgagttct atcatttatc aaggtgtact ccaagcagct cttgttatga
    38341 gtgtttatgg ccttgcgatt gcttacccag ttcatgtggg tgacaatcat gctattcatg
    38401 cagatgccct aacgatggcc tttgcaaccc ttggtttgat tcagctcttc catgcctaca
    38461 atgtcaagtc tgtctaccaa tccatcttga cagttggccc attcaagtct aagaccttta
    38521 actggtccat cttggtatct tttatccttc tcatggcaac aatcgttgta gaaccgcttg
    38581 aaggaatctt ccacgtaacc aaactagact tgtcacaatg gggaattgtt atggctggaa
    38641 gcttctcaat gattatcatc gtcgaaatcg ttaagtttat tcaacgcaaa ctcggttttg
    38701 acaagaatgc gatttaaggg aggtttcgga tgtcagcata tcaattaccg accgtatggc
    38761 aggatgaagc tagtaatcaa ggagctttta cggggctaaa cagaccaaca gcaggtgccc
    38821 gtttcgaaca aaacttgcca aaaggagaac aagcttttca gctttattca ctgggaacac
    38881 caaatggtgt gaaggttact atcttattgg aagaattact agaagctggt tttaaggaag
    38941 cggcttacga cttgtataag attgctatca tggatgggga tcaattcggc tcagactttg
    39001 tgaagctcaa tccaaattcc aagattccag ccttattgga ccagtcaggt actgaaaacg
    39061 taagagtctt tgagtctgct catattcttc tttaccttgc tgagaaattt ggagcctttt
    39121 taccaagtaa tcctgtggaa aaggtagaag ttttgaattg gctattctgg caagcaggtg
    39181 cagcaccttt tctaggtggg ggatttggac atttcttcaa ttatgctcct gaaaaattgg
    39241 aatatcctat taaccgtttt acgatggaag tgaaacgcca gttggattta ttggataagg
    39301 aattggctca gaaaccttat attgcaggca atgactatac gattgcagat attgctatct
    39361 ggtcttggta tggacagtta gttcaaggaa atctttacca aggttctgca aaattcttgg
    39421 atgcctcaag ttatcaaaat ctagtaaaat gggcagaaaa aattgccaat cgtccagctg
    39481 ttaagcgtgg attggaagta acttatacag aaattaaata gcaaaaaagt catcttcgga
    39541 tggctttttg ctacagttga gggaaagggt ttgcagttat cggcttttgt gctataattg
    39601 ctataatata gtaaaaagca agaggagtgt gaggaagtgg aaaagaaaat tgtgaaggat
    39661 atcttatttt tatctcaagt gtctcagccg gcaagtcagg aggaccttta tcttgccaga
    39721 gatttgcagg atacactctt agcaaatcgt gatacctgtg ttggtctagc tgccaatatg
    39781 attggggtgc agaagcgcgt gattatcttt aatcttggct tggttcctgt ggtcatgttt
    39841 aacccagtgc ttctgtcctt tgaaggatcc tatgaggcag aagaaggctg tttgtccttg
    39901 gtaggtgtga gatcaactaa gcgttatgaa accataaggc ttgcctatcg tgacagcaag
    39961 tggcaggaac agaccattac cttgacaggc ttcccagctc agatttgcca gcatgagctg
    40021 gatcacttgg aaggacgaat catttaggag gaaagcaaat gaaacgaata gtctttgaac
    40081 ttatttttat cgcaacgacc tggtatatct ttttaccgcc ccttaacctg accagctggg
    40141 aatttctctt cttcctctgt gggcatttgt tagttgtggc aatattattt ggctttggca
    40201 aggggataaa ccttgtcaaa acggttcatg tgcgccacgg taaggcggaa gctgccttaa
    40261 atcttgaggg tttcaaaatc aatcggttag ggaaaattct gttagcttcg attggaggaa
    40321 ttcttctctt ggcagctttg gtttccttgg taacttccag catgtttcag gctaaaaatt
    40381 atgccaatgt agtcacggtt acggaaaaag actttactga atttcctaag agtgacacca
    40441 gtaaggttcc tatcctagat agaagtactg ctgaaaaaat tggagaccgc tacttgggtt
    40501 ccctaaccga taaggtgtcg caatacgtag cggcagatac ctatacccaa ttgacaattg
    40561 atgggaaacc ttatcgggtc acaccactag aatatgcaga ccctatcaaa tggtttaaca
    40621 atcaagccaa gggaatcggt gagtatatta aggtggacat ggtaactgga aatgcggatt
    40681 tggtggactt gaagacacca atcaagtatt cagactcgga gtattttaac cgtgatgtca
    40741 aacgtcacct gcgcttgaag tacccgacca aaatctttaa aactccatct tttgaggtgg
    40801 acgatgaggg caatcctttc tatgtagcaa cggtttacca aaagcaattt ggacttgctg
    40861 ttcctcgtcc tgcttcagtc attatcttgg atgctacaaa tggagaaacc aaggaataca
    40921 gcttatcaga tgttccagaa tgggtggaca ggatctatcc agcagaggaa accattgagc
    40981 aaatcaacta caacggcaag tacaaggacg gtttcttgaa tgccatgatt tccaagaaaa
    41041 acgtgaccca gactaccaat ggctataatt acttgtctat cggtaatgac atctatctct
    41101 acacaggtgt gacgtcggct aatgcggatg agagtaatct tggtttcatc cttgaaaata
    41161 tgcgaacagg agaaatcact aagtatagct tggcttctgc gacagaagaa tcagcccgtg
    41221 aatcagcaga aggtgctgtt caggagaaat cctacaaagc aaccttccca atcctcatca
    41281 acctcaatga caagcctctc tacatcatgg gcttgaagga caatgctggc ttggtcaaag
    41341 agtacgccct ggtagacgca gtcgagtacc aaaatgttat cgttgctact acagtggaag
    41401 agatgctcag caagtatgcc aataaaaacg accttgaaat tgacaatgca acgacagaaa
    41461 gcatcaatgg agtagtagca gacctcaaat cagctgttat caagggagac actgtctact
    41521 tctttaaagt tgatggcaag atatacaagg tcaaggcttc agtatccgat gaccttcctt
    41581 accttgaaaa tggtaaaacc ttcgaaggtc aagtaggaaa agacaattat ctcaagacct
    41641 ttaagctacg gtaaaaatag gtttttttca gaaagtatat gttataataa ggtaaattaa
    41701 gcctaatgga ggacaaagaa atgggttttt atttgatggt tgcttcaatg ctactcggac
    41761 tgctcgcttt gaagataggt ttttctcagt tcaaggagaa aaaagataaa ttcttatcta
    41821 tcttaacaag tttagctggc acagcccttg ttctcgtggc tgtctggtta ggatggccca
    41881 aataaataga aaaacctcgg tcaaaccgag gtttttcaaa tgaatttctt ggttgtggct
    41941 aaaaaatatg ctacactatc aatatgaaaa ttttaatccc aacagcaaaa gaaatgaaca
    42001 cagacttgcc aagtatcgag gcaattcctt taaaaccaga aagtcaggcc gtgcttgatg
    42061 ccttggctct ctattctgcc agtcaattgg agagtttcta caaggtatca gctgagaaag
    42121 cggcggaaga atttcaaaat atccaagctt tgaaaaggca aactgctcaa cactatccag
    42181 ccttgaaact ttttgatggg cttatgtacc gcaacattaa gagagataag ctgaccgagg
    42241 cggaacaaga ttatcttgaa aatcatgttt tcattacctc ggctttgtac ggtgttgttc
    42301 cagtcttgtc acccatggct cctcaccgtt tggatttttt gatgaaatta aaagtcgctg
    42361 gtaagacttt gaagagccat tggaaggcag cctatgatga aactctgaag aaggaagaag
    42421 tgattttctc tctcttgtca tcagagtttg agactgtatt ttctaaggaa atcagagcaa
    42481 agatggtgac cttaaaattc atggaggata gaggcggtca gctgaagatt cactcaacta
    42541 tctccaagaa agcgcgcggg gcctttctaa cagctttaat agaaaatcaa gtacaaactg
    42601 tgggggaagc acgtcgcttg aactttgctg gatttgttta ccgagaagat ttgtcacaac
    42661 cacagggatt ggtttttgta aaggaagtat agaaatcaga tattttgtat ttggcaatat
    42721 gtatcatcag ctattttagt ttataaatga gaaaaaagcg aacaagctag tcttctgagt
    42781 gtcagaaaag tagtcttgtt cgcttttatt atgttatact cttcgaaaat ctcttcaagc
    42841 cacgtcagtg tcgccttacc gtatatatgt tactgacttc gtcagttcta tctacaacct
    42901 caaagcagtg ctttgagtag cttgcggcta gcttcctagt ttgctttttg atttttattg
    42961 agtgttagtt acttgatagc ttcgaccaag tcttgagctt gtttttcaag tgagtttagg
    43021 actgtttctt caagaaccaa ttttccgtct gcccaggcag agtcattaac acgtgcagca
    43081 gtgaaatcac caacgccttg tgtacggata aatggcaaga ggtctttgta gatagcgaaa
    43141 agttgatcgt gccctgcatt ggctacagat gatactgtga caaacttgtc ttgaagggca
    43201 gaaacgccac gtgtatcaga caagtcaagg gcacgagata gccagtcaag caagtttttc
    43261 actgtaccag ggatagagaa gttgtagact ggagagaaaa tccagatagc atccgcaacg
    43321 agaactgctt cacgagcagc agctacagct ggatgtgttg gaacttccaa atcttggctg
    43381 aagagaggaa gggctgaata atcaaggtag ctaacttccg ctttaccagc aagtgctttc
    43441 tcagcttcga gcgccatttg gtggttgaaa gaaccttgac gtagtgatcc gacgataaat
    43501 aatacttttt tagacatgat gtgtctcctt tttcttaaaa tttcgagaac tctctcgttg
    43561 ttataaaata tattacaaca aaacaaaaga acttgcaaga aatttgctca gagtttattt
    43621 gaaaattgta aaatttcgga aactctagtc atttgtgact gaaaaagtaa gaactgtttc
    43681 actttcaaaa tcggttttgt ttgaagggag aaatagaatt ggttgctcaa agcacagctt
    43741 tgaggttgca gataaagctg acgtggtttg aagagatttt cgaagagtat tcttatattc
    43801 acttgtaata aagcttaata gatggtaaaa tagacgagtg aaaaaaagac aaaacaaagc
    43861 aaaaaataat ctactgtggc agtatggtct agggatgacg attttgtttg tggttatcag
    43921 tgcttccttt ctgtatatgg tttctcttag catgaaaccc tatcaaacag ctaaaagtga
    43981 aggagaaaaa ttagctcagc agtatgcagg attagagcag gccgatcagg ttgatttata
    44041 caatggcttg gaatcttatt acagcgttct tggtcgtaat aaacagcaag aagcacttgc
    44101 tgttctgatt ggaaaagatg atcataagat ttacgtttat cagctaaatc agggtgtttc
    44161 acaagaaaaa gcagaaacgg tttctaagga aaagggagct ggcgaaattg acaagattat
    44221 ctttggtcgt tatcaagata agccaatctg ggaagtcaag tcaggatctg atttttatct
    44281 agtagatttt gaaacaggag cattggtcaa caaggagggc ctatgaaatt atccaaccgt
    44341 gttttagaaa tggaagaaag tgtgactttg gctgctggag cccgtgccaa agcactgaag
    44401 gctgagggca gagatatttt gtctctaacc ttgggtgagc cagatttcac tactcccaaa
    44461 aatatccaag atgccgccat tgcatcgatt cgagatgggc gtgcttcttt ttatacagta
    44521 acctcaggtc tgccagagct taaggcggcg gtcaatagct actttgagcg cttttacggc
    44581 tattctgtag cgtcaaatca agtgacagtc gctgcgggag ccaaatattc tctctatacc
    44641 ttctttatgg ctgtggtcaa tccaggtgat gaagtcatca tcccaacccc atactgggtt
    44701 agctatggag atcaggtcaa gatggcagaa ggcgttcccg tctttgtttc tactaaggaa
    44761 gacaatcact ttaaggtgac cgtagatcag ttagaagcag ctcgcactga caagaccaag
    44821 gttttggtgc tgaattcgcc atctaatccc acaggtatga tttacacccg tgaggaactc
    44881 ttggcaattg gaaactgggc tgtagaaaat gatattctca tcctagcaga tgatatctat
    44941 ggccgcttgg tttataatgg tcatgagttc acaccgattt ctagcctatc ggaagcgatt
    45001 cgcaagcaaa cagtggtcat caatggtgtg tctaaaacct atgccatgac tggttggcgg
    45061 attggttatg ccgttggaga agcagacatt atcgctgcca tgtccaagat tgcaggtcaa
    45121 acaacttcga atccgtcagc agtagcccaa tatgcagcag ttgaggctct atcaggtgag
    45181 caagatactg tagaaagcat gcgtcaggcc tttgaggaac gtcttaatac tatctatccc
    45241 ctccttgcag aggtgccagg atttgaagtg gtcaaaccgc aaggggcctt ctatctcttc
    45301 ccaaatgtca aaaaggccat ggagatgaaa ggctacacgg atgtgacaga ctttacaact
    45361 gctatcttag aagaagccga agtggccttg gtaacaggag ctggatttgg agcaccagaa
    45421 aatgtccgcc tcagctatgc gacagaccta gacacgctta aagaagcagt cgaacgcttg
    45481 aaagcattta tgggtagtga gaatgattga tcattttgag attaaggtaa aggatttaca
    45541 aatttcagaa ggattttata ggagttttct cgctcctttg gactataaaa tggcttttaa
    45601 gactagttct ctaattagtt ttctatcccc gaacagccct catcctggtg gtgatttttg
    45661 gctgactcag ggaacacaag atcctgttca ttttgctttt ttagcagaaa ataaggaaga
    45721 agttcaggct tgttatgagg ctggcttaga ggcaggtggg cgagacaatg gggttcctgg
    45781 ttatcgaagt gagcatccga tttattatgc tgcttttatg attgacctgg atgggaacaa
    45841 tatagaggtg gtttgccata aagaataaaa aagaaaagga aaaataatga caaaacgtgt
    45901 aacgattatt gatgtaaaag actatattgg tcaagaagtg acgattggcg cttgggttgc
    45961 caacaaatca ggaaaaggga aaatcgcttt cttacaattg cgtgatggaa cagccttctt
    46021 tcaaggtgtg gcttttaaac caaactttgt cgaaaaattt ggtgaagaag tgggacttga
    46081 gaagtttgat gttatcaaac gcttgagcca agaaacgtct gtttatgtga caggtattgt
    46141 caaagaggac gaacgttcta aatttggcta tgagttggac atcacagaca tcgaagtgat
    46201 cggtgaatct caagactacc caatcacacc aaaagaacac ggaacagact ttttgatgga
    46261 taaccgtcac ttgtggctac gctctcgtaa gcaagtagct gtgttgcaaa tccgtaacgc
    46321 tattatctat gcaacttatg agttctttga caagaacggt tttatgaagt ttgacagccc
    46381 aattctttca ggaaatgcgg cagaagattc tacagaactc tttgaaactg actacttcgg
    46441 aacgccagcc tacttgagcc aatcaggtca actttaccta gaagcagggg ctatggctct
    46501 tggtcgtgtc tttgactttg gtccagtttt ccgtgctgaa aaatcaaaaa cacgccgtca
    46561 cttgactgag ttctggatga tggatgctga gtactcatac ttgacacatg atgagtcgct
    46621 tgacttgcaa gaagcttatg tgaaagctct tctacaaggt gttcttgacc gcgcgcctca
    46681 agccttggaa accttggaac gtgatacaga actcttgaaa cgctacattg cagagccatt
    46741 caaacgtatc acttacgatc aagccattga cctcttgcaa gagcatgaaa atgatgaaga
    46801 tgctgactac gagcatcttg agcatggtga tgactttggg tcaccacacg aaacttggat
    46861 ttcaaaccac tttggtgtgc caacatttgt catgaactat ccagcagcca tcaaggcttt
    46921 ctacatgaaa ccagttcctg gaaatccaga gcgcgtgctt tgtgcagact tgcttgctcc
    46981 agaaggctat ggagaaatta tcggtgggtc tatgcgtgag gaagattacg atgcccttgt
    47041 cgctaagatg gatgaacttg gcatggatcg tacagaatat gaattctacc ttgaccttcg
    47101 taaatacggt acagttccac acggaggatt tggtatcggt atcgaacgta tggtaacctt
    47161 cgcagcagga acaaaacata tccgtgaagc tattccattc ccacgtatgt tgcaccgtat
    47221 caaaccataa gaacaggaaa acgcccatgt ggcgtttttt cgaattctag tgtttttact
    47281 tgcgtaaaaa aattttttct agtataatag tttattgtga gcgaacctca cttacccctt
    47341 gcaaagtctt ggggtcatta gaccaaaagg aggaacatat caatggctaa atacgaaatt
    47401 ctttatatca ttcgtccaaa cattgaagaa gaagctaaaa acgctttggt agcacgtttt
    47461 gactctattt tgactgacaa cggtgcaact gttgttgaat caaaaacttg ggaaaaacgt
    47521 cgtcttgcat acgaaatcca agatttccgt gaaggacttt accacatcgt taacgttgaa
    47581 gcaaatgacg atgcagctct taaagagttt gaccgtcttt caaaaatcaa cgctgacatt
    47641 cttcgtcaca tgatcgtcaa aattgacgcg taagaaggta aactatgatt aacaatgttg
    47701 tacttgtagg gcgtatgaca cgtgacgctg agttgcgtta taccccatca aatgtagcag
    47761 ttgcgacttt tactcttgca gtaaaccgta catttaagag tcaaaatggt gaacgtgagg
    47821 ctgattttat caatgtcgtt atgtggcgcc aacaggctga aaatcttgct aactgggcta
    47881 aaaaaggctc acttatcggg gtgacaggtc gtatccagac tcgtagttac gataaccagc
    47941 aaggacaacg tgtctacgtg acagaggtcg tggctgagaa tttccaaatg ttggaaagcc
    48001 gtagtgtgcg tgagggtcac acaggtggag cttactctgc accaactgca aactattcag
    48061 cacctacaaa ttcagtacca gacttttcac gtaatgaaaa tccatttgga gcaacaaacc
    48121 cattggatat ttcagatgat gatttaccat tctaatggac aactaaactt ataaaggaga
    48181 aaaaacatgg ctcaacaacg tcgtggcgga ttcaaacgcc gtaaaaaagt tgattacatc
    48241 gcagcaaaca aaattgaata tgttgattac aaagatactg agcttcttag ccgtttcgtt
    48301 tcagaacgtg ggaaaatcct tcctcgtcgt gtaacaggaa cttcagctaa aaaccaacgt
    48361 aaagtaacaa cagctatcaa acgcgctcgc gtaatggctt tgatgccttt cgtaaacgaa
    48421 gattaaagaa aagacccggt tgggtctctt tttcatgagc ttgaaaacaa gaaagcgaat
    48481 taagacccca acgggtcttt tttcacaagc tttgaaatga gagagcgagt taggctcagt
    48541 ggcttccttt ttacgagttt gaaaacaaga gaacacatta aaagcacgat ggagcttttt
    48601 cataaatatg tctcttttct catccaagaa attaaaataa aaatgataaa ctttttgaaa
    48661 ataggggatt tgcctacttt atgatataat ggaaagagtt agattgaaag aggtagtgag
    48721 atggacgcga aattaagata caaggcaaag aagatcaaga ttgtcttttt tgatattgat
    48781 gatacattgc ggaattcaaa gacagggttt attccaacta caattcccac tgtttttaaa
    48841 cagttgcgtg aaaaaggaat tttaacagga atcgcctctg gacgtggcat ttttggtgtt
    48901 gttccagaga ttcgtgatct caagcctgac ttttttgtaa ctttgaatgg ggcttatatc
    48961 gaagataaaa aaggtcaggt catttatcag catcagattg aaaagtcaga tgttgaggag
    49021 tatatctctt gggctaagca agaaggaatt gagtatggct tggttgggag tcatgatgcc
    49081 aagttgtcga ctcgcaccga tatgatgagt gaagctatca atccaattta tcccgactta
    49141 gatgtagatc ccgatttcca tgaaaaagaa gatatctatc agatgtggac ttttgaagat
    49201 aagggagatg acttgcactt gcctgacagt ctctcagaca aacttcgcat ggttcgttgg
    49261 catcaacatt cgtctgatat tgtgccgatt tcaggctcca aagcgacggg ggtggaaaag
    49321 gttgtggaac accttggctt gaaaccagag aaggtcatgg tttttggaga tggtctcaat
    49381 gacttggaac tctttgatta tgctggaatc agcgttgcca tgggaatttc tcatgataaa
    49441 atcaaagaaa aagcagatta tattacaaaa acattagaag aagatggcat ttttgatgcc
    49501 ttagaagtat ttggtatggt agaaaaagaa ttgcattttc cacaagtaga cattgaaaca
    49561 gtagaaggtc ttcttgcgac tattaagacc aatcacggag acttacgtat caagcttttc
    49621 cctgaacatg ctcctaaaac agtggctaac tttgtatctc tttcaaaaga tggctactat
    49681 gatggtgtca ttttccaccg tattatcaag gactttatga tccaaggtgg agacccaact
    49741 ggaactggta tgggtggcga gtcaatctac ggcgaatctt ttgaggatga attctcagaa
    49801 gagctttaca atatccgtgg tgctctttcc atggcaaatg ctggtccaaa taccaacggc
    49861 agccagttct ttatcgtgca aaaccaacac ctaccttatt cgaagaaaga aattactcgt
    49921 ggtggttggc cagaaccgat tgcagaaatc tatgccaatc aaggtgggac acctcaccta
    49981 gaccgccgtc acacggtttt tggtcagtta gctgatgaag catcttacgc tgtcttggat
    50041 gccattgctg ctgttgagac aggagctatg gacaagccag ttgaagatgt tgtaattgaa
    50101 actattgaaa tcgaggacta agatgaaaat cggtgataag ctaaaggggc gtattacagg
    50161 gattcagccc tacggtgcct ttgttgagtt agagacgggt gatacggggc tgattcacat
    50221 ttcagaaatt cggacaggat ttattgaaaa tattcatgaa accttgaaag tcgatgaaga
    50281 ggttcaagtt caggtactgg atttagatga atttacgggg aaagccagtc tttctatccg
    50341 cactttggag gaagaaaagt accagtttcc tagacggaga cgcttttcaa gtgaccgctt
    50401 taactacggt tttgctccct ttcgacgaat gctaccaatc tggactggag aagctctgca
    50461 ccatttaaaa aagaagaagt agtttagagt tttatatttt ttgtaatgtt aatataaatt
    50521 tattataata ggaccatgga agaagaacaa ttattaaaat caggagagcg cattaaccag
    50581 ctcttttcga cagatatcaa aatcattcaa aatagagagg tttttagcta ttcggtggat
    50641 agtgttctct tatcacgatt tccacgtttt cctaagaagg ggttgattgt ggatttctgt
    50701 gctgggaatg gagcagtggg gctttttgct agcactcgta ctcaagcaca gatattgtct
    50761 gttgagattc aggagcgttt ggcggatatg gctgaacgct ctgtccgttt gaatggatta
    50821 gaggagcaaa tgcaggtcat ctgcgatgat ttgaaaaata tgcctgctca cattcagggg
    50881 agtaaggtag atatgatttt gtgtaatcca ccctatttca aggtggatcc ttattctaat
    50941 ctgaacgaga gtgaacatta tctcttggct cgacacgaaa tcacgactaa tttggaagaa
    51001 atctgtcgta gtgcccagag tattctcaag tctaatgggc gtttggccat ggttcatcgt
    51061 cctgatcgac ttctggatat tttggatacg ttaaaacgac ataatctagc ccctaagcgc
    51121 ctgcagtttg tttatccaaa aagagaaaag gaagccaata tgcttttgat tgaggcgatc
    51181 aaggatggct caacaagtgg ctttaaggtc ttacctcctt tgattgtcca caatgatgat
    51241 ggctcttata cgcccgaaat cgaagagatt tattatggat cataaggctt atatgtacgt
    51301 tctggagtgt cgtgatggat cctactatat aggctatacg actgatgtga gaagacgcct
    51361 cgctatccac aatagtggga agggagccaa atatacacga gcacgcttgc cagtcaaact
    51421 tatctatgct caaggttttg ccagtaagga agaagccatg tcggctgaag ctcttctcaa
    51481 gcgtaagaag aggccacaga aggaagaatt tttatctgaa aatcaagata gaaatttact
    51541 cagttatttt gaagaatcgt ggggagtcct ttgactcctc ttacctttgt caaaaagcga
    51601 aaaaaatgct acaataaaga aaataaacaa aatgaggtat tatcatgtcc aagattctag
    51661 tatttggtca ccaaaatcca gactcagatg ccatcgggtc atctgtagct tttgcctacc
    51721 ttgcaaaaga agcttacggt ttggatacgg aagctgttgc ccttggaact ccaaatgaag
    51781 aaacagcctt tgtcttgaac tattttggtg tggaagcacc acgtgttatc acttctgcca
    51841 aagcagaggg ggcagagcaa gttatcttga ctgaccacaa tgaattccaa caatctgtat
    51901 cagatatcgc tgaagtagaa gtttacggtg ttgtagacca ccaccgtgtg gctaactttg
    51961 aaactgcaag cccactttac atgcgtttgg agccagttgg atcagcgtct tcaatcgttt
    52021 accgtatgtt caaagaacat ggtgtagctg tgcctaaaga gattgcaggt ttgatgcttt
    52081 caggtttgat ttcagatacc cttcttttga aatcaccaac aacacaccca acagataaaa
    52141 tcattgctcc tgaattggct gaattggctg gtgtgaactt ggaagaatat ggtttggcaa
    52201 tgttgaaagc tggtaccaac ttggctagca aatctgctga agaattgatt gatatcgatg
    52261 ctaagacttt tgaactcaac ggaaataatg tccgtgttgc ccaagtgaac acagttgaca
    52321 tcgctgaagt tttggaacgc caagcagaaa ttgaagctgc aatgcaagct gcaaacgaat
    52381 caaacggcta ctctgacttt gtcttgatga ttacagatat cgtcaactca aactcagaaa
    52441 tcttggctct tggtgccaat atggacaagg tcgaagcggc tttcaacttc aaacttgaaa
    52501 acaatcatgc cttccttgct ggtgccgttt cacgtaagaa acaagtggta cctcaattga
    52561 ctgaaagctt taatgcgtaa gattttgggt gtcagctcaa aatcggaaag tctagtttgc
    52621 cttatatcga aaggagtttc ggctcctttt ttctaggagt gaagtatgtt agaaaatggc
    52681 gatttgattt ttgtgagaga tgggtcagac atgggacagg ccatccagac ttccacaggt
    52741 aactatagcc atgttgccat ttatttggat gggatgattt atcatgctag tggacaggct
    52801 ggtgttgtct gtcaagaacc ggcagacttc tttgagtcca atcatttgta cgacctctat
    52861 gtttacccag aaatggatat ccagtcggtg aaggaaagag cttgcagaca tcttggagca
    52921 ccctacaatg cttctttcta tccagatgca gctggtttct actgctccca gtatatagca
    52981 gaaatcctac ctatttttga aactattcct atgaaatttg gagatgggga acaggagatt
    53041 agtgattttt ggagggagta ttacatagaa ctaggtctgc ctgttcctct gaaccaagct
    53101 gggaccaatc ctagtcagtt ggcagcatcg cctctgttac aatgtaaaga aaggaatctt
    53161 catgattcag atttttaatc catctcgttt gacgagacag ccatttttgg agaattgatc
    53221 cgctatctgg accagtatga ggatgtgatt ctacgggaaa ttaaggctca atttccagat
    53281 gttgcagttg ataaactcat ggaagagtat ataaaggcaa gcttgattct acgtgaaaat
    53341 aagcgctatt acctcaattt tcctacgctt gaatcacttg atagtcttga actggatcaa
    53401 gagatttttg tcagagaagc tagtccggtc tatcaagcct tgttggagca gagttttgag
    53461 acggaattgc gcaatcaaat caatgcagct attttagttg aaagacggac tttgcgcgca
    53521 ttaaaatgac cctgtccaat tatttttaca aggtcaaaca gcagtatcct ttgacagaaa
    53581 aacagcagga gctctatgac attttaggag atgttaatcc tgagtatgca ctcaagtata
    53641 tgacggcttt tttgttgaaa tttctcaaaa aagaccagct tatgcagaaa tgccgtgata
    53701 tctttgtgga cagtttggtt gtcttaggct atattgtgca aaatgaagat agaaagtatg
    53761 agttggctat cgattttgat aaggagagat taactttcta cttagcgtga tttcttgttt
    53821 ctgagcacat tgtttgactt tccttagtat tcggtataaa ctatatgtaa ccggtaacac
    53881 atatcggaat aaactaaagg agacaatcat atgtcacttg aaaacaaatt ggaacaagca
    53941 acaggcgctg tcaaagaagg ttttggtaaa gttactggag acagcaagac agaacttgaa
    54001 ggagctgttg aaaaaacagt tgctaaggca aaagacgttg tagaagacgc aaaaggtgct
    54061 gtagaaggtg ccgttgaagg tttgaaaaac gtttttacta aataatagga aaaaatcaag
    54121 ggtttcattt tcccttgatt ttttctattc ttataaataa ttttctgcga cggctgtatc
    54181 tcctgggtag gattctttct tgccctggat gatttggtaa caatcggctc ccttacccgc
    54241 aataataact gcatctaatt cgtgatttgt gatagccatt gccgccttga tggcttcttg
    54301 gcgatccgca atcttttcaa caggatgatt gatgtagcta ctaatttcat ctgcaatggc
    54361 cattgggtct tcatagttag ggtcatcagc agtcagaaag acttgaatct cagggtgttg
    54421 attgaggagg aggccaaagt ccttacgacg actttctccc ttgtttcctg ttgatcccag
    54481 aaccagagca atctttccgg tttgatgagt ttcaaccaca ttgatgagtt ttttcagact
    54541 atccccattg tgggcatagt cgatgaagac cttggctcca tttttctgag tgaggacttc
    54601 catacgacca ggaacgcggg ttgcagcgat gccttttttg atgtcctcaa gacttgctcc
    54661 gagacggaga caagcaagtc cagcagcaac tgcattttct tggttgaagt tgccaatgag
    54721 ttggatatca taatctccag cgagtttacc cgtagctgaa aagctaaagg ctttggaatt
    54781 ctcgatttgg ttatcaaatt ggctaccata gaaatcatgg tcttgatctt caacctgttc
    54841 tttcaagact gagaagtggt ccatgtcact gttaatgatg actgctcggc tattttccat
    54901 caagagacgc ttgtggtaga aatagtcttc aaagctagag tgttcaatcg ggccgatatg
    54961 gtcaggagtg atgttaagaa agactcctac atcaaaggtc agtccataga ctcgatggac
    55021 tagataggct tgactggaga cttccatgat gaggtgggta cggtcatttt gcacagcctg
    55081 attcatcatg tcaaagaggt caatactctc aggggttgtc aacgctgact taaaaaaagt
    55141 ctcgccatca agagttgtgt tcatggtcga caacatagca ggtctatgcc cttgagataa
    55201 gatgttatag gcgaaatagg ttgctgttgt cttaccctta gtaccagtaa aggcaaggag
    55261 tttgagtttc tcttgtggat taccatagaa ctccatggca atcaaactca tggctttctt
    55321 tatatcgttc acaatgatga cagggatatc gacttcgtag tccttttcag ctacatacca
    55381 agctaaacct tgtgttatag cagaaagaag gtattctttt ttaaaggcag cgccttttgc
    55441 aaaaaaaaga gtgtcttctg ttacttttcg gctgtcgtag ctgatgctat caaaaataac
    55501 tttgctgtag ttgtagtggt aatgaccttg gtcaataatt tcgcgaaaaa ggccatcttt
    55561 ctttaaaata tctaatacgg tttcaatctt aatcatactt tctattgtaa accgaaagtc
    55621 gtaaatttac aagtaacaag gaaaagttta taatggaaga taaggagttt ttcctagtta
    55681 tcaaaattga atgaggaatc tatgtcgcac gaaaacaatc accagcaggc ccagatgtta
    55741 cgggggactg cttggctaac ggctagtaac tttatcagtc gcctactcgg ggctgtttac
    55801 attatccctt ggtacatctg gatgggggct tatgcagcta aggcaaatgg tctctttacc
    55861 atgggttaca atatctatgc ttggttcttg ttggtttcaa cagcggggat tccagttgcg
    55921 gtggccaagc aagttgccaa gtataatacc atgcgagaag aagagcatag ctttgccctg
    55981 attcggagct tcttaggctt tatgacagga ctaggtctgg tttttgcttt agtcttgtat
    56041 gtctttgctc cttggctagc agacttgtct ggcgtgggca aagacttgat cccaatcatg
    56101 caaagcttgg cttggggagt cttgattttc ccgtctatga gtgttatccg aggatttttc
    56161 caagggatga ataacctcaa accctatgct atgagccaaa ttgctgagca ggtcattcgt
    56221 gttatctgga tgctcctagc aacctttatc attatgaagc tcggttcagg agattatcta
    56281 gcagccgtta cccaatcaac ctttgctgcc tttgtcggta tggtagccag ttttgcagtc
    56341 ttgatttatt tccttgccca agaaggttca ctcaaaagag tctttgaaac aggagataag
    56401 attaacagta agcgtctctt ggttgatacc attaaggaag ccattccttt tatcctgaca
    56461 gggtctgcca tccagctctt ccagattttg gatcagctga cctttatcaa tagtatgagc
    56521 tggtttacca actacagcaa tgaggacttg gttgtcatgt tttcttattt ctcagccaat
    56581 cctaataaaa tcacgatgat tttgatttct gtaggggttt cgattgggag tgttggtttg
    56641 ccacttttga cggaaaacta tgtcaagggg gacttgaaag cagcttctcg tctcgttcag
    56701 gacagtctca ccctactctt tatgttcttg ctaccagcaa cggttggagt ggttatggta
    56761 ggagaacctc tttatacggt cttctatggt aagccagata gtttggctct ggtcttattt
    56821 gtctttgcag ttttgcagtc tattatttta ggcttgtaca tggtcttgtc tccaatgctt
    56881 caggccatgt tccgcaaccg caaggccgtt ctctatttta tctatggttc tattgccaag
    56941 ctagtcttgc aactacctac catcgccctc ttccacagtt atggtccttt gatttcaaca
    57001 accattgctc tcatcattcc taacgtcttg atgtatcggg atatttgtaa agtaactggt
    57061 gtcaagcgca aggtgatttt gaagcgaacc attttaatca gtttgctgac cctagtcatg
    57121 tttctgttaa taggaaccat ccagtggctg ttaggatttt tcttccaacc aagtggacgt
    57181 ttgtggagct tcttttatgt agctcttgtc ggtgccatgg ggggtggact ttatatggtt
    57241 atgagtctgc gtacctattt attagataag gtaataggaa aagcccaagc agatcgcctg
    57301 cgagcaaaat ttaagctttc gtaaggtagc atttataaat aaaaggaata agttgaacaa
    57361 tcttttagga gaacttgaaa cttattcctt ttttagcgtc aaaatagcta aaattatctt
    57421 tcaaaaatag aaaatgaggt ttttttgatt ttttggaaaa aacaattgac taaacaaacc
    57481 cagagttgta taataaaaca aatatttaaa gcaggaggtt ctggaaatga aaaagtctaa
    57541 gagcaaatat ctaaccttgg caggtcttgt cctgggtaca ggagttttat tgagcgcgtg
    57601 tggaaattct agcactgcat caaaaaccta taactatgtt tattcaagtg atccatctag
    57661 tttgaactat ctagcagaaa accgcgcagc aacatccgat attgttgcaa atttggtaga
    57721 cgggttatta gaaaatgacc aatatgggaa tattattcca tcattagcag aggattggac
    57781 tgtttctcag gacggtttga cctataccta caaacttcgt aaggatgcca agtggtttac
    57841 ttctgaggga gaagaatatg cgcctgtaac tgcccaggat tttgtgacag gtttgcaata
    57901 tgcagctgat aaaaaatcag aagctttgta tctagtgcag gactctgttg ctggtttgga
    57961 tgactatatc actggtaaaa caagcgactt ttcaactgtc ggtgtcaagg cacttgatga
    58021 ccaaacggtt caatatactt tggttaaacc agaactttac tggaattcaa aaacacttgc
    58081 aacgatactt tttcctgtta atgcagattt cctgaaatca aaaggggatg attttgggaa
    58141 ggcggatcca tctagtattt tgtacaatgg acctttcttg atgaaagcac ttgtctcaaa
    58201 atctgctatt gaatataaga aaaaccctaa ttactgggat gctaagaatg tctttgtaga
    58261 cgatgtgaaa ttgacctact atgatggtag cgaccaagaa tcactggaac gtaattttac
    58321 agctggtgct tatactacgg ctcgtctttt tcctaacagc tccagctatg aagggattaa
    58381 agaaaaatac aaaaacaata tcatatatag tatgcaaaat tcaacttcat atttctttaa
    58441 ttttaaccta gataggaagt cttacaatta tacttctaaa acaagtgaca ttgaaaagaa
    58501 atcgactcag gaagcagttc tcaataaaaa cttccgtcag gctatcaatt ttgcttttga
    58561 cagaacatct tatggggctc agtctgaagg gaaagaaggt gcaacaaaga ttttgcgtaa
    58621 cctagtggtt cctccaaact ttgtcagtat caagggaaaa gactttggtg aagttgtagt
    58681 ctctaagatg gtcaactatg gtaaggaatg gcaaggtatc aactttgcgg atggtcaaga
    58741 cccttactac aatcctgaga aagccaaggc taagtttgcg gaagctaaga aagaactcga
    58801 agcaaagggt gttcaattcc caatccactt ggataagact gtggaagtaa cagataaagt
    58861 aggcatacaa ggagttagtt ctatcaaaca atcaattgaa tctgttttag gttctgataa
    58921 tgtagtgatt gacattcagc aattaacatc agatgagttt gacagttcag gctactttgc
    58981 tcaaacagct gctcagaaag actatgattt atatcatggc ggttggggac ctgattatca
    59041 agacccgtca acctatctcg atatttttaa tactaatagt ggaggagttc tacaaaatct
    59101 tggactagag cctggagaag ccaatgacaa ggctaaggaa gttggactgg atgtctatac
    59161 tcaaatgttg gaagaagcta ataaagagca agatccagcc aaacgttatg agaaatatgc
    59221 tgatattcaa gcttggttga ttgatagttc tttagttctt ccaagtgttt cgcgtggggg
    59281 aacaccatca ttgagaagaa ccgtaccatt tgctgctgcc tatggtttaa ccggtacaaa
    59341 agggattgaa tcatataaat acctcaaagt acaagataag attgtcacaa cagacgaata
    59401 tgcaaaagct agagaaaaat ggttgaaaga aaaagaagaa tccaataaaa aagcccaaga
    59461 agaattggca aaacatgtca aataaaatct aattgtagat aagtttgtgt aagaagtctt
    59521 tgtgcttaaa aacgcataat atcaggtata taaaatccta gatgttatgc gttttgttat
    59581 aggaagattt attagatttt atcctcaaat tgagttattc ccgactttat ccgttgaaat
    59641 attataagga gtatttatga aattaaaatt attaagagta gatactaagg tgattatggg
    59701 gagtttctta cttgttctgt ctagtctact tgctttgttg cttcccctta tcttaaaggg
    59761 tttaatagat gggagttcta ttgaaaatat aggttccaaa gtatttcaat cgtttttgat
    59821 ttttattggt caagccttgt tttcttctat tggttactat ctgtttagtc aatcgggtga
    59881 aaaaaagata gcaaaaatca ggaaaaaagt gatagagggg ttgatttatg cagagaaatc
    59941 cttctttgat aagagccaaa gtggggagtt gacttctgcc attgtcaatg acacgagtgt
    60001 cattcgtgag tttttaatta cgactttccc aaatattatt ctgagtttag ttatggtact
    60061 tggttccatt gtagtcttat ttagtcttga ttggaatctt tctctacttt tattcatcac
    60121 tcttccttgt atgatgttta ttatcttgct cctttccaat atcagtgaaa agtatagtcg
    60181 tcgtttacag gaggaaatcg gatttttaac agggtaattg actgaaaaga ttcaagaaca
    60241 tgaattaatt aagactaacc aagcagagaa aagtgtacag gatgttttgg ataattgtat
    60301 tgaaagggta caaaacaatt cactgaaatc agatagggtt acttcttttg agaccccgtt
    60361 tgctctctta tttatctttg cgactatagc tgtgatgcta acctatgggg gttatcgggt
    60421 cagcgcagga tatatatctg tgggaacctt ggtttcgttt ttgatttacc tctttcaatt
    60481 acttaatcct attagtaata tagctaattt tgtaactgtt tattctagga gcaagggatc
    60541 ttcagttgca ctggagaact tgcttgcagt tcctaaagaa aaatttgagt gaggaaaatc
    60601 ggtatcagga caagggttga attt
//
LOCUS       DAVBOU010000006        59938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBOU010000006 DAVBOU010000000
VERSION     DAVBOU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.006"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(93..551)
                     /locus_tag="VQ879_000338"
     CDS             complement(93..551)
                     /locus_tag="VQ879_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3142564.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(548..988)
                     /locus_tag="VQ879_000339"
     CDS             complement(548..988)
                     /locus_tag="VQ879_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3142565.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1194..3143
                     /gene="mutL"
                     /locus_tag="VQ879_000340"
     CDS             1194..3143
                     /gene="mutL"
                     /locus_tag="VQ879_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3142566.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3468..3935)
                     /locus_tag="VQ879_000341"
     CDS             complement(3468..3935)
                     /locus_tag="VQ879_000341"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3142567.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3936..5141)
                     /locus_tag="VQ879_000342"
     CDS             complement(3936..5141)
                     /locus_tag="VQ879_000342"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3142568.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ879_000343"
     CDS             complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ879_000343"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3142569.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ879_000344"
     CDS             complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ879_000344"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3142570.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7015..7129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ879_000345"
     CDS             7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ879_000345"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3142571.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7889..8452
                     /locus_tag="VQ879_000346"
     CDS             7889..8452
                     /locus_tag="VQ879_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3142572.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8449..9126
                     /locus_tag="VQ879_000347"
     CDS             8449..9126
                     /locus_tag="VQ879_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3142573.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9263..10294)
                     /locus_tag="VQ879_000348"
     CDS             complement(9263..10294)
                     /locus_tag="VQ879_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3142574.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10549..11232)
                     /locus_tag="VQ879_000349"
     CDS             complement(10549..11232)
                     /locus_tag="VQ879_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3142575.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11244..12188)
                     /locus_tag="VQ879_000350"
     CDS             complement(11244..12188)
                     /locus_tag="VQ879_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3142576.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ879_000351"
     CDS             12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ879_000351"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3142577.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15144..16205
                     /locus_tag="VQ879_000352"
     CDS             15144..16205
                     /locus_tag="VQ879_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3142578.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16337..16735
                     /gene="spx"
                     /locus_tag="VQ879_000353"
     CDS             16337..16735
                     /gene="spx"
                     /locus_tag="VQ879_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3142579.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16801..17370
                     /locus_tag="VQ879_000354"
     CDS             16801..17370
                     /locus_tag="VQ879_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3142580.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17457..17723
                     /locus_tag="VQ879_000355"
     CDS             17457..17723
                     /locus_tag="VQ879_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3142581.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ879_000356"
     CDS             17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ879_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3142582.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18162..18467
                     /locus_tag="VQ879_000357"
     CDS             18162..18467
                     /locus_tag="VQ879_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3142583.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18773..20023
                     /locus_tag="VQ879_000358"
     CDS             18773..20023
                     /locus_tag="VQ879_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3142584.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20020..20562
                     /locus_tag="VQ879_000359"
     CDS             20020..20562
                     /locus_tag="VQ879_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3142585.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20708..22240
                     /gene="cls"
                     /locus_tag="VQ879_000360"
     CDS             20708..22240
                     /gene="cls"
                     /locus_tag="VQ879_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3142586.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22318..22461
                     /locus_tag="VQ879_000361"
     CDS             22318..22461
                     /locus_tag="VQ879_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142587.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            22498..24036
                     /locus_tag="VQ879_000362"
     CDS             22498..24036
                     /locus_tag="VQ879_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3142588.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ879_000363"
     CDS             24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ879_000363"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3142589.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26375..26515
                     /locus_tag="VQ879_000364"
     CDS             26375..26515
                     /locus_tag="VQ879_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142590.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26559..27065
                     /locus_tag="VQ879_000365"
     CDS             26559..27065
                     /locus_tag="VQ879_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142591.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ879_000366"
     CDS             27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ879_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3142592.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27645..28262
                     /locus_tag="VQ879_000367"
     CDS             27645..28262
                     /locus_tag="VQ879_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3142593.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ879_000368"
     CDS             28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ879_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3142594.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29042..29668
                     /gene="rplC"
                     /locus_tag="VQ879_000369"
     CDS             29042..29668
                     /gene="rplC"
                     /locus_tag="VQ879_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3142595.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29693..30316
                     /gene="rplD"
                     /locus_tag="VQ879_000370"
     CDS             29693..30316
                     /gene="rplD"
                     /locus_tag="VQ879_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3142596.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30316..30612
                     /locus_tag="VQ879_000371"
     CDS             30316..30612
                     /locus_tag="VQ879_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3142597.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30630..31463
                     /gene="rplB"
                     /locus_tag="VQ879_000372"
     CDS             30630..31463
                     /gene="rplB"
                     /locus_tag="VQ879_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3142598.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ879_000373"
     CDS             31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ879_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3142599.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31860..32204
                     /gene="rplV"
                     /locus_tag="VQ879_000374"
     CDS             31860..32204
                     /gene="rplV"
                     /locus_tag="VQ879_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3142600.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ879_000375"
     CDS             32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ879_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3142601.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32874..33287
                     /gene="rplP"
                     /locus_tag="VQ879_000376"
     CDS             32874..33287
                     /gene="rplP"
                     /locus_tag="VQ879_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3142602.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33297..33503
                     /locus_tag="VQ879_000377"
     CDS             33297..33503
                     /locus_tag="VQ879_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3142603.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ879_000378"
     CDS             33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ879_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3142604.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33814..34182
                     /gene="rplN"
                     /locus_tag="VQ879_000379"
     CDS             33814..34182
                     /gene="rplN"
                     /locus_tag="VQ879_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3142605.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34260..34565
                     /gene="rplX"
                     /locus_tag="VQ879_000380"
     CDS             34260..34565
                     /gene="rplX"
                     /locus_tag="VQ879_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3142606.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34589..35131
                     /gene="rplE"
                     /locus_tag="VQ879_000381"
     CDS             34589..35131
                     /gene="rplE"
                     /locus_tag="VQ879_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3142607.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ879_000382"
     CDS             35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ879_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3142608.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ879_000383"
     CDS             35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ879_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3142609.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36293..36829
                     /gene="rplF"
                     /locus_tag="VQ879_000384"
     CDS             36293..36829
                     /gene="rplF"
                     /locus_tag="VQ879_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3142610.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36913..37269
                     /gene="rplR"
                     /locus_tag="VQ879_000385"
     CDS             36913..37269
                     /gene="rplR"
                     /locus_tag="VQ879_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3142611.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ879_000386"
     CDS             37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ879_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3142612.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ879_000387"
     CDS             37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ879_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3142613.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38122..38562
                     /gene="rplO"
                     /locus_tag="VQ879_000388"
     CDS             38122..38562
                     /gene="rplO"
                     /locus_tag="VQ879_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3142614.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38575..39885
                     /gene="secY"
                     /locus_tag="VQ879_000389"
     CDS             38575..39885
                     /gene="secY"
                     /locus_tag="VQ879_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3142615.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40036..40674
                     /locus_tag="VQ879_000390"
     CDS             40036..40674
                     /locus_tag="VQ879_000390"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3142616.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40791..41009
                     /gene="infA"
                     /locus_tag="VQ879_000391"
     CDS             40791..41009
                     /gene="infA"
                     /locus_tag="VQ879_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3142617.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ879_000392"
     CDS             41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ879_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3142618.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ879_000393"
     CDS             41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ879_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3142619.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ879_000394"
     CDS             41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ879_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3142620.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41977..42912
                     /locus_tag="VQ879_000395"
     CDS             41977..42912
                     /locus_tag="VQ879_000395"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3142621.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ879_000396"
     CDS             42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ879_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3142622.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43575..43841
                     /locus_tag="VQ879_000397"
     CDS             43575..43841
                     /locus_tag="VQ879_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3142623.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43851..45188
                     /locus_tag="VQ879_000398"
     CDS             43851..45188
                     /locus_tag="VQ879_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3142624.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45432..46124
                     /locus_tag="VQ879_000399"
     CDS             45432..46124
                     /locus_tag="VQ879_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3142625.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46227..47872)
                     /locus_tag="VQ879_000400"
                     /pseudo
     CDS             complement(46227..47872)
                     /locus_tag="VQ879_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(48054..48940)
                     /locus_tag="VQ879_000401"
                     /pseudo
     CDS             complement(48054..48940)
                     /locus_tag="VQ879_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289375.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48953..50074)
                     /locus_tag="VQ879_000402"
                     /pseudo
     CDS             complement(48953..50074)
                     /locus_tag="VQ879_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(50660..51436)
                     /locus_tag="VQ879_000403"
     CDS             complement(50660..51436)
                     /locus_tag="VQ879_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3142626.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            51558..52304
                     /locus_tag="VQ879_000404"
     CDS             51558..52304
                     /locus_tag="VQ879_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3142627.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            52317..53297
                     /locus_tag="VQ879_000405"
     CDS             52317..53297
                     /locus_tag="VQ879_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3142628.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            53492..53812
                     /locus_tag="VQ879_000406"
     CDS             53492..53812
                     /locus_tag="VQ879_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3142629.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            53858..54166
                     /locus_tag="VQ879_000407"
     CDS             53858..54166
                     /locus_tag="VQ879_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3142630.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            54183..55481
                     /locus_tag="VQ879_000408"
     CDS             54183..55481
                     /locus_tag="VQ879_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3142631.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            55632..58070
                     /locus_tag="VQ879_000409"
     CDS             55632..58070
                     /locus_tag="VQ879_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3142632.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            58089..58757
                     /locus_tag="VQ879_000410"
     CDS             58089..58757
                     /locus_tag="VQ879_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3142633.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            58775..59863
                     /locus_tag="VQ879_000411"
     CDS             58775..59863
                     /locus_tag="VQ879_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3142634.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT        18330 a        10822 c        12968 g        17818 t
ORIGIN      
        1 tcctgttctt atttgatttc actatagtaa ggtgcagcag gataaagaaa aaccgagaag
       61 tttctttctc ggatttgctt attatgaggt tcctattttc tatgctccaa gagttgattg
      121 atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca
      181 atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaagggaa ccaaccagca
      241 agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga
      301 agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct
      361 gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc
      421 acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt
      481 gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact
      541 tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg
      601 tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag
      661 agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg gttggcaaga
      721 gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta
      781 gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct
      841 gatcatcgat tttccctttg attttttctc tttggtccag attttctgcg aactcgatga
      901 ctttctggac tttatctgtc ggctgaggtg cttggacaat cagcttttcc tcctcgtaag
      961 tctcactaat ctgtagttct actttcatag ttttctctcc ttttcagtta tacaaggttg
     1021 tgatcacttc ctgtatatcc ttattaaaca ctattttata gcccatggca aggaaccttg
     1081 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
     1141 tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc
     1201 atattattga attgccagag atgctggcaa accaaatcgc agctggggag gtcattgaac
     1261 gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga
     1321 ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg
     1381 gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa
     1441 atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta
     1501 ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca
     1561 agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa
     1621 ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga
     1681 gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc
     1741 ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg
     1801 gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg
     1861 aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga
     1921 ctcgggctaa ccgcaattat atcagcctct tcatcaatgg tcgttatatc aagaacttcc
     1981 tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga cgttttccac
     2041 tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta
     2101 agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca gaagctattg
     2161 caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga
     2221 ccgtgcgcaa tcgtgagaag gtggatcaaa ctattctccc actcaaagaa aatacgctct
     2281 actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag
     2341 aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga
     2401 ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc
     2461 atccagagtt agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag
     2521 catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc
     2581 aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg
     2641 aggagtaccg tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct
     2701 atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag
     2761 aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc
     2821 ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc
     2881 ttttgaccaa ggaagtttct atcaagaaat accgagcaga gttggctatc atgatgtctt
     2941 gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct
     3001 atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc
     3061 attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc
     3121 tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag
     3181 aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catggaaata
     3241 gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca
     3301 gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg
     3361 tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa
     3421 ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat
     3481 gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct
     3541 gctttagtgc cagctcgttc tatggcttgt tcaattgtat ctgtcgttag cacaccaaac
     3601 ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat
     3661 acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca
     3721 tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc
     3781 caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca
     3841 gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata
     3901 ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg
     3961 tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt
     4021 tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca
     4081 ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca
     4141 atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc
     4201 atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc
     4261 tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta
     4321 tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg
     4381 gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga
     4441 tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta
     4501 ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt
     4561 aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct
     4621 gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt
     4681 ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca
     4741 cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata
     4801 tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc
     4861 gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca
     4921 accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat
     4981 cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa
     5041 attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc
     5101 tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg
     5161 ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag agttatccat
     5221 cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg
     5281 tttactctta agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac
     5341 tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac
     5401 tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt
     5461 ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag
     5521 tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt
     5581 aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa
     5641 atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt
     5701 taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc
     5761 aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg
     5821 agatagtcat ttcctatttg agaaaatgca taaggtttca atctaatagc gtcatttggc
     5881 aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca
     5941 atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg
     6001 cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat
     6061 aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat
     6121 agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat atcatttgct
     6181 gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata
     6241 ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg
     6301 actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt tcttgcttct
     6361 tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt
     6421 gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt
     6481 aagttaagac actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt
     6541 atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt
     6601 gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag
     6661 ggttcaagtg ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca
     6721 tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta
     6781 tcttttacaa taattgcgcc aaccatagga ttgggattga cgtaaccagc ccctttttgt
     6841 gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa
     6901 tataccttga ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa
     6961 atgctctgaa atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat
     7021 cttctttcat ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct
     7081 cgtgggctat accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca
     7141 gatgattata gtacttaatt ttgaatatgt caacagataa atacagattg tttttgatat
     7201 actgtatttg tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata
     7261 aacgaaataa gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat
     7321 tactgccaaa tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa
     7381 tccttatgcc tattcaggtc aggttaatca ggaggatcag atttatgtgc atcaggttgt
     7441 gcgtgaggac gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct
     7501 tagtctgatt tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga
     7561 tgacaatgct ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt
     7621 ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt
     7681 agttgcagga gatgaccttc ctgccaaggt cgcagtacaa gcaagtgctg aaaaccaaga
     7741 attggaagaa gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa
     7801 aatcaagaaa ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct
     7861 taaaatgttg gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac
     7921 caacccgctc tacatcgcct atcatgatga ggagtggggt cagcccctcc atgatgacca
     7981 agcattgttt gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt
     8041 actcaacaaa cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc
     8101 agagatgact gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag
     8161 agccaagatt tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta
     8221 cggctctttt gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt
     8281 tcctgattat cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct
     8341 caaaaaacga ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc
     8401 agggctagtt gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac
     8461 aaaaataagg gaattctgat ttttgcgatt ctctatacaa tcctctttgt gtttgatggc
     8521 gttaaattgc tggcttcttt aatgccatct gtcattgcaa attatcttgt ttatgtagtt
     8581 ttagctttat atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt
     8641 agaaagacta aaagaaaatt cttctttggc gtcttaacag gatggctctt tctcattctg
     8701 atgactgttg tctttgaatt tgtatcagag atgttgaagc agtttgtggg attagatgga
     8761 caaggtctaa atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct
     8821 gtttttgctt gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg
     8881 cattacttgc aggaacggtt gccaggttta ctaagcatta ttctggtagg acttgttttt
     8941 gctctgactc atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta
     9001 ggtggaggcc ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc
     9061 ctacttgttc acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta
     9121 aaatgaaatg agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     9181 attctagttt caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa
     9241 agctgagaaa cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg
     9301 catctacatg agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat
     9361 tcagattata gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt
     9421 cgtcatggaa agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata
     9481 tgccagtgtc ctttaaagtt agcaacattt ttttgaagtc ttctggctta ggcttttctt
     9541 cgcttgtttc gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt
     9601 atttttggca gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg
     9661 attcgaggca accaccgagg attttcccct cgaactgagc acttccttgc aacaagtcaa
     9721 aacctgtatt tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc
     9781 gttcctcata ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc ttaatcaatt
     9841 ctttaaagta gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta
     9901 aaaaggattg accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg
     9961 ttgtatccga gaagccaaga aaaatttttt gcttgataac cttttggagt tggtcatttt
    10021 caaaaagata aggtagcaag cgataggtat cgtctccacc gatggcacat aggatcatgt
    10081 cgatgctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    10141 tgataaagtc taatcctttt aacgaatggg acaaaaagat gggattgagt cccagatcct
    10201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    10261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    10321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    10381 tactcttcga aaatctcttc aaaccacgtc agttttatct gcaacctcaa agctgtgctt
    10441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgaat ataactcaaa
    10501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    10561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    10621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    10681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    10741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg atccatagta
    10801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    10861 aagagtaatc aatccatagc cgaaagcttg gtctgccgca aagaaggttg tgagggcgct
    10921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttgggtc
    10981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    11041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    11101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    11161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    11221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    11281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    11341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    11401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    11461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    11521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcctc aaggtatttc
    11581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    11641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    11701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    11761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    11821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    11881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    11941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    12001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    12061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    12121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    12181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    12241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    12301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    12361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    12421 aggttcaggg aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta
    12481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    12541 agatgccatt gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa
    12601 tcctcgctcg acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc
    12661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    12721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc
    12781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    12841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    12901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    12961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    13021 tatcgacacc atggacgact cggagttgct cttctctgag cattatgcct gtccagtttg
    13081 tggatttact gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc
    13141 ttgtagtgag tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc
    13201 agatgccagc aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa
    13261 ctactatcca aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc
    13321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tacggctcag atggtaagga
    13381 attccatttc cattatgaaa atgaatttgg tggtgtgcgc gatatcgaca ttccgtttga
    13441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    13501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    13561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    13621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    13681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    13741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    13801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggtgtcc tctatatcct
    13861 agacgagccg tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa
    13921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    13981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    14041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    14101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    14161 tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    14221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    14281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    14341 gactattaca gggattgagc atgtcgaccg tttgattgat attaaccaga gccctatcgg
    14401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    14461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    14521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    14581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    14641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    14701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    14761 ggatgtaggt ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    14821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    14881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    14941 tttagctcgc tttgtagacg ccggcaatac agtcctcgtc atcgagcaca atctggatgt
    15001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    15061 catcatcgta acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca
    15121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    15181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    15241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    15301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    15361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gaacttgact cgtatcggtt
    15421 ttgaagatga gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga
    15481 acttgcttcc acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    15541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    15601 ttatcaaacc aggaaaaact gaaattgaga ttgccaactt ccttgatttc cgcatgcgtg
    15661 agttgggagc atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    15721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatc accatggact
    15781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    15841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    15901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    15961 ttgaggcagg ttatggtgac tactttactc acggcattgg ccacggtatt ggtctggata
    16021 tccatgagga accctacttt agtcagactt ctacagaaac tattaagaca ggtatggcct
    16081 tgaccgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    16141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    16201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    16261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    16321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    16381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    16441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    16501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    16561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    16621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    16681 acgatctgtc cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc
    16741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa
    16801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    16861 aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca
    16921 gttattgaaa atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca
    16981 gatgatggta gccagcagac acaaacaatt acttacaaag acaagacttt tttgagtcta
    17041 gctatccaac aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga
    17101 gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    17161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    17221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    17281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    17341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    17401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    17461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    17521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    17581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    17641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca
    17701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    17761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    17821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    17881 acaaggtgga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    17941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    18001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    18061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    18121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    18181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    18241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    18301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    18361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    18421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtaaaaa cgtccggggg
    18481 acgtttttag ccctgcgcta gaaattagaa acgcaggtag tctgggagac tgtatcagcc
    18541 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    18601 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    18661 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    18721 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    18781 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    18841 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    18901 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    18961 caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc gaatctgcat
    19021 taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg taaaggagat
    19081 ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc tgaccttggt
    19141 tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag tgggaattgg
    19201 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    19261 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    19321 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    19381 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    19441 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    19501 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    19561 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    19621 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    19681 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    19741 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    19801 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    19861 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    19921 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    19981 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    20041 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    20101 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    20161 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    20221 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    20281 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    20341 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    20401 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    20461 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    20521 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    20581 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    20641 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    20701 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    20761 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    20821 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    20881 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    20941 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    21001 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    21061 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    21121 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    21181 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    21241 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    21301 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    21361 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    21421 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    21481 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    21541 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    21601 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    21661 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    21721 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    21781 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    21841 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    21901 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    21961 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    22021 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    22081 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    22141 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    22201 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    22261 caaaccagcc ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    22321 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt acaccgcttt
    22381 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    22441 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    22501 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    22561 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    22621 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    22681 gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg gaagatttac
    22741 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    22801 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    22861 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    22921 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    22981 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    23041 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatcg
    23101 ctcctgttta ttgctgtagt gggtttaggc ttgttggtct ttaaccttgg gcatagacgc
    23161 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    23221 ccaactgcct actatagtgc tgcaacagga agttttgggg atgcgattag tggtattcgt
    23281 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    23341 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    23401 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgttgt aattttaggt
    23461 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    23521 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    23581 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    23641 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    23701 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    23761 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    23821 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    23881 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    23941 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    24001 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    24061 tagaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    24121 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    24181 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    24241 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    24301 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    24361 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    24421 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    24481 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    24541 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    24601 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    24661 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    24721 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    24781 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    24841 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    24901 atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    24961 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    25021 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    25081 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    25141 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    25201 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    25261 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    25321 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    25381 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    25441 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    25501 gcatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    25561 cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcatcta ggtaaagaag
    25621 aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc tatatcggct
    25681 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    25741 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    25801 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgcc
    25861 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    25921 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    25981 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    26041 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    26101 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    26161 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    26221 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    26281 ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    26341 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    26401 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    26461 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    26521 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    26581 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    26641 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    26701 aggaacagga aatgggaatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    26761 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    26821 ttctactaga agaaggtggg cacattggct actccatccg tccatctgaa agaggcaagg
    26881 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    26941 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    27001 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    27061 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    27121 tacaaggcct ttaactttgt tgatggcgaa ggcgtgcgta actctctcta tgtagcaggc
    27181 tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa tgctggcatt
    27241 ccctatacag cagaattaga agagcagatc atggcagatc ttggtcagcc ctatgttcaa
    27301 ggtttgactt tgttgggagg ggagcctttt ctcaatactg gcattctctt gccacttgtt
    27361 aagcggattc ggaaagaatt gtcagacaag gacatctggt cctggaccgg ctacacttgg
    27421 gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat tgatattctt
    27481 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcgtct
    27541 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    27601 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaaggct
    27661 tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg ggaatatacg
    27721 gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtcccaagct ttagattcta
    27781 ctacagtaaa tttgctagaa acagatccct atatcacctc cggacgctat ttggtagtac
    27841 ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgtat gaactggaga
    27901 gtttgcagag agatatcttt gccttgcagg cgggtatgga tgtcttgaca attgaagaac
    27961 cttggaaggc tagtgaagtc ttgtctggag ccaaaccaat tttgattgtc gaagggatgt
    28021 ctgttggttt tctacccaag gaactctttg aaaaaaccat ctgtttctac acggatgagg
    28081 agaccgaatt aaagcgacgc cttgctagag atacgactgt gagaaatcgc gatgcatcct
    28141 ttatattggc tagccatcag atgagacggg agcagtatct gcgatactat aaagaaactg
    28201 agtctaaggc ggatatctta gtggaccaat cagaagataa atttgatgtc aagaggactt
    28261 aacttatgta tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    28321 ctcaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct
    28381 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    28441 gcattgccac gcaacgccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    28501 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    28561 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    28621 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    28681 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    28741 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    28801 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    28861 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    28921 cactgcgtta gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag
    28981 cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct
    29041 catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg
    29101 cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac
    29161 tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt
    29221 gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat
    29281 tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt
    29341 cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt
    29401 tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg
    29461 tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg
    29521 gcgtatgggt ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga
    29581 aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat
    29641 caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa
    29701 cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt
    29761 atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag
    29821 ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa
    29881 accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg
    29941 gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca
    30001 aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt
    30061 cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct
    30121 tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc
    30181 agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt
    30241 tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga
    30301 ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc
    30361 tcaatggctc aacttgaagc aggaaaatat gtatttgaag ttgacactcg tgcacacaaa
    30421 cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac
    30481 acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa
    30541 actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct
    30601 gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa
    30661 acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa
    30721 aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag
    30781 ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata
    30841 aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca
    30901 tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg
    30961 aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc
    31021 cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg
    31081 gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat
    31141 acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta
    31201 cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta
    31261 gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc
    31321 cacacggtgg tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg
    31381 gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg
    31441 ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc
    31501 agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat
    31561 ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa
    31621 gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca
    31681 acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg taaacacgta
    31741 cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt
    31801 acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa
    31861 tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat
    31921 cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga
    31981 cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta
    32041 acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa
    32101 acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca
    32161 acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg
    32221 gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat
    32281 ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg
    32341 ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca
    32401 aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta
    32461 acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca
    32521 tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc
    32581 aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc
    32641 gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg
    32701 cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg
    32761 attacgcttg ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct
    32821 accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag
    32881 tacctaaacg tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag
    32941 gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca
    33001 ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta
    33061 aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta
    33121 tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga
    33181 tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc
    33241 acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga
    33301 aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg
    33361 cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg
    33421 gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa
    33481 cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata
    33541 atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg
    33601 tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat
    33661 acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa
    33721 ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca
    33781 tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa
    33841 gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga
    33901 cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt
    33961 ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct
    34021 cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa
    34081 gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt
    34141 ggcttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag
    34201 tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa
    34261 tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagacaag ggaacagaag
    34321 ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg
    34381 ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag
    34441 cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg
    34501 gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg
    34561 attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa
    34621 tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa
    34681 agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct
    34741 tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc
    34801 taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac
    34861 ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg
    34921 tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga actacacact
    34981 tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg
    35041 tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct
    35101 tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa
    35161 tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt
    35221 gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca
    35281 ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa
    35341 tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta
    35401 acaaaagcat cttggtaatt taagatatca agggtgtcaa aactccaagt aaaaatagga
    35461 aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc
    35521 cgggttcaat tgggcttgcc aatttgaacc cgagctacag ctttggcaaa aaagaccaat
    35581 ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct
    35641 ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca
    35701 aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag
    35761 ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc
    35821 ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca
    35881 tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg
    35941 tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg
    36001 gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc
    36061 aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg
    36121 taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc
    36181 tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa
    36241 ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg
    36301 tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt
    36361 tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat
    36421 ccgtgtggaa ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac
    36481 tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt
    36541 caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact
    36601 tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt
    36661 tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca
    36721 aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg
    36781 ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt
    36841 tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa
    36901 gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgtcaccgt
    36961 cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct
    37021 aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct
    37081 tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt
    37141 aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt
    37201 ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg
    37261 aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag
    37321 aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt
    37381 tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag
    37441 ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg
    37501 aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta
    37561 aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg
    37621 ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc
    37681 caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa
    37741 ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct
    37801 caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact
    37861 gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct
    37921 atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga
    37981 agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac
    38041 atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt
    38101 acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt
    38161 aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt
    38221 ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga
    38281 caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa
    38341 tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca
    38401 gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt
    38461 aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa
    38521 gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt
    38581 tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca
    38641 atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc
    38701 aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg
    38761 aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct
    38821 attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa
    38881 ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct
    38941 tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt
    39001 aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac agctggtagt
    39061 atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc
    39121 atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg
    39181 gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt
    39241 ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac
    39301 aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg
    39361 ttaaaggtaa accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg
    39421 cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta
    39481 gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt
    39541 attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc
    39601 ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat
    39661 atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc
    39721 attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga
    39781 acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac
    39841 ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat
    39901 cagtaaatac tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc
    39961 tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa
    40021 taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact
    40081 caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc
    40141 cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag
    40201 ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat
    40261 gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat
    40321 gccttggaca aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa
    40381 gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga
    40441 gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa
    40501 cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga
    40561 gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa
    40621 gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt
    40681 tttcgcactt gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt
    40741 tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag
    40801 acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg
    40861 ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact
    40921 atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac
    40981 gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag
    41041 taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg
    41101 ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg
    41161 agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc
    41221 attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg
    41281 aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg
    41341 tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa
    41401 acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg
    41461 tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg
    41521 taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg
    41581 aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt
    41641 atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc
    41701 aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa
    41761 tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt
    41821 cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat
    41881 gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg
    41941 cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat
    42001 ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt
    42061 ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga
    42121 gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt
    42181 gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac
    42241 gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt
    42301 gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc
    42361 ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct
    42421 gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat
    42481 acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt
    42541 ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta
    42601 gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt
    42661 gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat
    42721 cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt
    42781 atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat
    42841 cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta
    42901 aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac
    42961 gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa
    43021 ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac
    43081 gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg
    43141 aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct
    43201 cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg
    43261 aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat
    43321 tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta
    43381 ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga
    43441 aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa
    43501 ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga
    43561 attggagttt acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg
    43621 ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa
    43681 ctgtcttgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt
    43741 ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata
    43801 ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta
    43861 gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta
    43921 ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa
    43981 tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg
    44041 ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg
    44101 gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga
    44161 aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa
    44221 agggagatga gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct
    44281 gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata
    44341 tgggacgaat tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg
    44401 tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg
    44461 aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg
    44521 aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta
    44581 aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt
    44641 ttggtattgt ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg
    44701 tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc
    44761 tcttgaacga ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat
    44821 ctggtgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct
    44881 ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga
    44941 ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag
    45001 caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag
    45061 gcgatatgat tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg
    45121 cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta
    45181 aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg tatactataa
    45241 tcattaaata aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt
    45301 tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt
    45361 caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg
    45421 gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta
    45481 acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag
    45541 ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt
    45601 cgagtgattc tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc
    45661 aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg
    45721 atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc
    45781 acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg
    45841 gttgggctga aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg
    45901 caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta
    45961 ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg
    46021 tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt
    46081 accgagagct aggacgtgag aagatggaag aaggttctat ttaatcagtc tagacttgct
    46141 tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc
    46201 ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc
    46261 ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct
    46321 acaccgtaat ttcctctgag aatctctgta taaatagcca cagtcattgt tcttgttttg
    46381 acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg
    46441 gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa gatattgaga
    46501 cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta
    46561 gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg
    46621 aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa
    46681 atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca
    46741 attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat
    46801 agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc
    46861 atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaaa taccatacct
    46921 gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata
    46981 attccgtaga ctgttgcata aatggcagcc atttttcctt ttgtagtttt tttaggctca
    47041 attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg
    47101 aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg
    47161 ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata
    47221 ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg
    47281 aaactaggag aggtaaaaca accgttacga taggtttaaa tccgaaggac cccatgcttt
    47341 cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata
    47401 ccagtgggaa tagttgcagt gtaaagacaa gtatacttcc tttgaatcca taaatatcga
    47461 tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtctcagca
    47521 agagaatcca ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata
    47581 tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc
    47641 ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct
    47701 cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat tgtccttcat
    47761 gtataagtgc ttgcttgagc acggtaacga taggataaac gagaaagaca agataggtaa
    47821 gaaagatgaa gaaagaggaa gctgtccaaa tatttagttt tttacattcc atggttgact
    47881 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    47941 cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa aagttgattc ttcactaact
    48001 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagctagacg
    48061 ctatcgctaa tagttccttc aatatctcca gattcatctt tgataaactc ttcgggacga
    48121 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctggcattcg aagggcatag
    48181 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    48241 tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata gagttctttt
    48301 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    48361 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    48421 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    48481 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    48541 tgtccaccac tgagtttatc gggttttcga tccgcatatt gagcaatttg catgagttca
    48601 agatacttgt tggtctgttg aatcaattct tcttttgcat aagaccaaaa gcaacgttgt
    48661 ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg atattgcgtt
    48721 tgctgggttc catattattg atttttgtat catcgaagta aaattctcaa tctttgatac
    48781 tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa gctccaagaa
    48841 gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt
    48901 ggtagatttt tttggcgtta ataattttga tctcactcat agtgaacctc ttttactgtt
    48961 tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat ttattcttga
    49021 tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc atgttttcgc
    49081 ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt gtatcttgta
    49141 cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt ttagattttt
    49201 taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag actaccttaa
    49261 tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga ccaacagtca
    49321 tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt ttatagtata
    49381 ttgaaactag aatagtacac atctacttct aaaacattgt tagaaatcga tttgactgtc
    49441 ctgattaatt tgtcctgttc ttatttcatt ttactatacc atcaataagt gtgaaaagat
    49501 cttttacata agaccaagcc ttattatctt tgtaaccacc ttgagcttgt agcatatttg
    49561 ttaattgagc aaaggcgcta gaagagtttg ctgggtcagc agttgcgatt tttcctttta
    49621 gttcaggttt gagaaggtcg ctatatcctt cgatgttcat gcctttagtt aaatcagggt
    49681 ggacgattaa aacactacca tctagtgtat aaggagtaga gaagccagtt gtgttttgat
    49741 attctttgat aacattatca ttttcttttg aaatatagtt ttcaaagagt tctccgtggg
    49801 tagcatattg tgtataagaa ccaccaaaga taacatcagc tacaggaact tctttttctg
    49861 actctagttt tttgaaaagt tctccagtac cagcttgaat cagttctatt ttgataccat
    49921 atttttcttc aaaggcagga atagttgctc caattaagcc ttctgagttt ggtgaataaa
    49981 cgactagcga accaccgtct cctttatcag atgaactgtc atcggcagat tcattagaag
    50041 aacaagcagc ataatacatc catttctttt tcatgatgga tacctccgtt gtgttattta
    50101 agtttatttt aaaacaatgt aagcgttttt aaaacctaca attctattct atagtgtatt
    50161 gaatctataa cagtacacct tgactgctaa aatatttcta taaattaatt tgactttcct
    50221 gatagagatg ttcacatctt atttcaattc actatattag agtaaaattc tctacaaaaa
    50281 aaagaatagc ctattttact atttttccga gtgatttcaa ttcctttggg gaaatatgga
    50341 gatacttttt aaatcctgac aaatggttgt ttctttttct aaatcggtga tactgtatcg
    50401 gagaatgcgc gtgaggtcac aaaggctgcg atagagcttc tatggagaat ttctttttgg
    50461 agagattttt taaaggaatg agacatccgc tacctccttg gaaggttttt tgtgataagt
    50521 atagcagttt aaaaattcta gagcaaggta aaatagaaaa ggtttggcta aaatttttta
    50581 gctaaacctt ttgaaaagtt aagtatgtat tatagatgct tgttatctgc aaatatctag
    50641 agcatttcaa ggaaataaac tagaaataac aattaatatg gtggttcaga aatacctttt
    50701 gataatcaat aagatcttca ggatgaagtg cgttgactcc atccatttca tatttccgat
    50761 ttaataaacg atatttgttt tcaccaaatt gatgaaaagg gagtagttga acttggtcga
    50821 tatttaatga gttaaataga gtagcgaatt tttctgcatc ctctaaacta ttgttaaaat
    50881 taggaataac tgggattctt aaaacgatag ttttattttg agaaaaagca taatgaatgt
    50941 ttttaataat catttgatta aaaaccccag tcactttttt atgttttata gaattataat
    51001 gttttaggtc tgtgtagata aaatccacat attgaattaa atcgataaat ttttcatgat
    51061 caacaaaggc agtagtttca atggcagtgt gtatgtgatg ttctttagct gattttaaga
    51121 tggctttagc aaattcaaac tgagcaaata tttcacctcc tgataaagtt aaacctccac
    51181 cggattcttc gtaaaattct ttgtctttta atacctctgt aataatttct tctacagtct
    51241 tttcttcacc gactaaggtg aatttctctc gttgagcatc tttcattttt tcaggtttca
    51301 ttctttgaga ttcaggatta gaacaccatg gacagcgcag aggacatcct tttaaaaaaa
    51361 cagttgtacg aatacccggg ccgtcatgaa ttgaaaagtg ttgaatatta aaaataattc
    51421 ctttagatat ttccataaga gttcctcctc ttcataagtc tatcctatca caaaaacgaa
    51481 agaaaaacaa ttacgaacga aaggttaatt tgttgttttt tgctttttat tttggtagaa
    51541 taaaacggag gtgtaaaatg aaaagattgg aacaaattat taaattagta tcagaatatg
    51601 aaaagatcga cgttaataca ttatcggaaa aattaaatgt atcgaaagta acgattagaa
    51661 aagatttaga taaattagag tcaaaaggtt tattacacag agagcatgga tatgctgtat
    51721 taaatagtgg agatgactta aatgtacgtt tgtcaattaa ttatgaaatt aagagaaaaa
    51781 ttgttcagga agcagtaaaa ttggtgtcag ataatgaaac aataatgata gaatctggat
    51841 cgacctgtgc tttacttgct gaggaaattt gcaagcaaaa aagaaatgtt acgattgtaa
    51901 caaattcatt ttttatagca aattttgtga gagcttatga ttcatgtcgt attattgttc
    51961 ttggtggaga gtttcagaag gattcacagg ttactgtggg acctttatta aaagaaatga
    52021 tacagacttt tcatgtgcgt caagcttttg ttgggacaga tggctacgat aaagagatgg
    52081 gctttacagg aaaagattta atgcgcagtg aggtagttca atatatttca gcagcgtcgg
    52141 ataaagtcat tgtactaact gactcaagta aatttgataa aaggggtaca gtaagaagat
    52201 ttgctttaag tcaagtctat gaagtaataa cagacgaaaa actttctaaa caaaatatag
    52261 ctacattaga aaatgctggg ataatggtta aggtagtttc gtaagaggtt aagtgtatga
    52321 atcaagatag gaataaactg ctctctaaaa ttgcttatct gtattatatt gaaaacttaa
    52381 atcagtcaca aatagcagca aaattaggaa tttatagaac ctctattagt agaatgttaa
    52441 cagaagcaag gaatgcagga attgttaaaa ttgaaataga gaattttgat accaatatgt
    52501 ttaagttgga aaattatgta aaagaaaaat atggtctgga aagtttagaa attattccaa
    52561 atgaatttga tgataatcca acaattttat ctgaaagaat ttctcaagtt gcagcaggtg
    52621 tccttaggaa tctaattgat gataatatga aaattggctt ttcttggggg aaaagtttaa
    52681 gtaatttagt agatttaatt cacagtaaaa gtgtccgaaa tgttcacttc tatcctctag
    52741 caggtggtcc tagtcacata cacgctaaat accatgtgaa tacactgatt tatgaaatgt
    52801 ctagaaaatt tcatggagag tgtacattta tgaatgcaac gattgtgcaa gaaaataaat
    52861 tgttagcaga tggtattttg caatcaagat attttgaaaa tttgaaaaat agttggaaag
    52921 atttagatat agctgtagtc ggaattggtg attttagcaa taaaggaaag catcaatggt
    52981 tagacatgct tacagaggat gactttaaag aattgaccaa agttaaaact gtaggagaaa
    53041 tttgttgtcg attttttgat tcaaaaggta aagaagtcta tgaaaactta caggaaagaa
    53101 cgatagcaat ctctttggaa gatttaaaaa atattcctca aagtttagct gttgcttacg
    53161 gtgatacgaa agtatcttcg attctttctg tcttgcgtgc taatttagta aatcatttga
    53221 ttacagacaa aaatacaatt ttaaaagttt tggaagaaga tggggatttg acttttagag
    53281 agattctagg tgagtgaaaa tgatagactg attcagttta tcgtttttct ttttagttga
    53341 ttgcacattt gtgcttatat aaacaaaaat agtttatctg ttgtttttgg attgacaact
    53401 ttattatgta gttgtattct atagttacaa aagaaaattt taaaatttca aatgaaaaaa
    53461 gctttttaca tagtgaaatg aggaggaatt tatggaaatt attgttccag atcaaattat
    53521 catgggttta attttatatg ctggcgatgc gaaacaacat atttataaag cattagatta
    53581 cataaagaac ggtacatgtg aacgatgtga agaagaaatc cagttagctg atgccgcctt
    53641 attagaagct cataatctac aaacaaaatt cttggcacag gaagcgtctg gtacaaagac
    53701 agaaattaca gctctctttg ttcattcaca agatcatctc atgactagta tgacggagat
    53761 taatttaatc aaagaaatta ttagtttgag aaaagaactt cataaaaaat aatactagag
    53821 tattatcatt gttattaaca tagaggagga aaacataatg gtgaagattg gtttgttttg
    53881 tgcagcaggt ttttctactg gtatgcttgt aaataatatg aaaattgcag cgcaagctag
    53941 tggagttgag gcagaaatag aggcgttttc tcagtctaaa ttagcggatt atgcgccaaa
    54001 tatagatgtt gcactattgg gtccacaagt tgcttataca ttagataaat caaaagaaat
    54061 ttgtgataag tgtgatgttc cgatagctgt tattccgatg atggactatg gtatgttaga
    54121 tgggaaaaaa gtattagatt tggccctatc tttgattagt gggtaagaaa aggagattta
    54181 ttatgtcaaa gatggatgtt cagaaaatca ttgcaccgat gatgaagttt gtgaatatgc
    54241 gtggcattat agctctaaaa gatgggatgt tagcaatttt gccattgaca gtagttggta
    54301 gtttgttctt gattatggga caattgccgt tcgaaggatt aaataagagc attgctagtg
    54361 tttttggagc taattggaca gagccgttta tgcaagtata ttcaggaact tttgctatta
    54421 tgggtctaat ttcttgtttt tcaattgcct attcttatgc taagaatagc ggagtagagg
    54481 ctttaccagc tggagttcta tctgtatctg cattctttat tttgctaaga tcatcttata
    54541 tccctaaaca aggtgaggcg attggggacg ctattagtaa agtttggttt ggaggccaag
    54601 gaattatcgg tgctatcatt ataggtttgg tagtaggaag tatttatacc ttctttataa
    54661 agagaaaaat tgttattaag atgccagaac aagttccaca agctattgcc aaacagtttg
    54721 aagcaatgat tccagcattt gtaattttct tatcttctat gattgtatat attttagcga
    54781 agtcattgac taatggcgga acattcatag aaatgattta ttctgctatt caagttccgt
    54841 tgcaaggttt aactggatct ttgtatggtg ctattggaat tgcattcttt atatcatttt
    54901 tgtggtggtt tggtgttcat gggcaatcgg tagtaaatgg agtagtgaca gctctgcttt
    54961 tatctaatct tgacgctaat aaagctatgt tagcctctgc taatctatca ttagaaaatg
    55021 gtgcacatat tgttactcaa caatttttag attcattttt aattctatca ggttcaggga
    55081 ttacgtttgg tcttgtagtt gccatgcttt ttgcagcaaa atcaaaacaa taccaagcct
    55141 taggaaaagt tgcagctttt ccagcaatat ttaacgtaaa tgagccagtt gtatttggat
    55201 ttccgattgt catgaatcca gttatgtttg tacctttcat tcttgttcct gtacttgcag
    55261 ctgtgatagt atatggagct attgcaacag gtttcatgca gccattctca ggggtaacat
    55321 tgccttggag tacaccagct attctatcag gatttttggt gggtggatgg caaggtgttg
    55381 tgactcagtt attagtattg gtgatatcta cagtggttta ctttccattc tttaagatac
    55441 aagatcgttt agcttaccaa aatgaaatca aacaatctta gaggtatttg tgtgttactg
    55501 ttaaactcac acatttgtgc taaaaattag agagttaaaa tttttctagt taaaagcttg
    55561 aaaatttcta taaaaatcgg tattatattt tcgaaagaaa taaaaatatt ttcgaaagaa
    55621 aggtgcttac gatggtaaat acagaagtag caagaacaac aatcaagaca gaatattttg
    55681 gcagccttac tgaaaggatg aacaaatatc gagaagatgt tttaaataaa aaaccttata
    55741 ttgatgctga gagagcagtt ctagcaacac gcgcctatga acgatacaag gaacaaccta
    55801 atgtcctaaa acgtgcatat atgctgaaag aaattttgga aaatatgtct atctatattg
    55861 aagaagaatc tatgattgcg ggaaatcaag cttcttccaa taaagatgct cctatttttc
    55921 cggaatatac gctagaattt gttctcaatg agttggatct ttttgaaaag cgtgatggag
    55981 atgttttcta tattacagaa gaaacaaaag aacaacttag aagtattgct ccgttttggg
    56041 aaaataataa tttacgtgct agagctggtg ccttattacc tgaagaagtg tcagtttata
    56101 tggaaacagg attcttcggt atggaaggta agatgaattc tggagatgct cacttagcag
    56161 ttaactatca gaaacttttg caatttggtt taagaggttt tgaagagcgg gctcgtaaag
    56221 caaaagtagc tctagattta acagatccag caagtattga taaatatcat ttttacgact
    56281 ctatatttat tgtaatcgat gctattaaag tatatgcaaa gcgctttgtt gctcttgcta
    56341 aaagtttagc cgaaaatgca aatcctaaac gtaagaaaga attacttgag attgcagata
    56401 tttgctctag agtcccatat gaaccggcaa ctacttttgc agaagctatt caatcagttt
    56461 ggtttattca atgtatttta caaattgaat ctaatggcca ctctctttca tatggccgtt
    56521 ttgatcaata tatgtatcca tatatgaagg ctgatttaga aagtggtaaa gaaacagaag
    56581 atagcattgt tgaacgtctg acaaatcttt ggattaagac aattacaatt aataaggttc
    56641 gcagtcaatc acatacattt tcttcagcag gaagtccttt atatcaaaat gttacaattg
    56701 gtggacagac tcgagataag aaggatgctg ttaacccatt atcttatttg gtattaaaat
    56761 cagttgcaca aacccatcta ccgcaaccta atctaactgt acgttaccat gcaggtttag
    56821 atgctcgttt catgaatgag tgtattgaag tgatgaaact tggttttggt atgcctgcat
    56881 ttaataatga tgagattatt attccttctt ttattgcaaa aggagtattg gaagatgatg
    56941 cttatgatta cagtgccatt ggatgtgttg aaacggcagt tccagggaaa tggggctatc
    57001 gttgcacagg tatgagttat atgaacttcc ctaaggttct acttatcacg atgaatgatg
    57061 gaattgatcc ggcttcgggt aaacggtttg caccaagctt tggtcatttt aaggatatga
    57121 agaacttttc tgaattagaa aatgcttggg ataaaacact aagatatttg acacgaatga
    57181 gtgttattgt tgaaaattct attgatttat cattggaacg agaagttcct gatattctat
    57241 gttcagcatt gactgatgat tgtattggtc gtggaaaaca ccttaaagaa ggtggagcag
    57301 tatatgatta tatatcagga ttgcaagttg gaattgcaaa tttgtcggat tcattagctg
    57361 caattaaaaa attggtgttt gaggaagaac gtataagccc aagtcagctt tggcatgcac
    57421 tggaaacaga ttatgccgga gaagaaggta aggtcattca agaaatgttg attcatgatg
    57481 cacctaagta tggtaatgat gatgattatg ctgacaaatt ggttactgct gcttatgaca
    57541 tttatgttga tgaaattgct aaatatccta atacacgtta tggaagaggg cctattggag
    57601 gaattcgtta ttcaggaaca tcttctatat cagccaacgt agggcaggga cgtggaacat
    57661 tagcaactcc agatggacgc aacgcgggta caccgttagc agagggttgt tcaccatcac
    57721 ataatatgga tcaacacggc cctacatctg ttttaaaatc tgtttcaaaa ttaccaacag
    57781 atgaaatcgt aggtggggtt ctcttaaatc agaaagtaaa tcctcaaacg ttagccaaag
    57841 aagaagataa attaaaacta attgctttgt tacgaacatt ctttaatcgt ttacatgggt
    57901 accatattca atacaatgtt gtttccagag agacgttgat tgacgctcag aaacatcctg
    57961 aaaaacacag agacttaatt gttcgtgttg caggatactc tgcattcttc aatgttcttt
    58021 ctaaggcaac ccaagatgac attataggac gtactgagca tactttgtaa aataaagagg
    58081 ttctttttat ggaatttatg cttgacacat taaatttaga tgagattaaa aagtggtctg
    58141 aaattttgcc gctagctggg gtaacttcaa atcccactat tgcaaaaaga gagggttcta
    58201 ttaatttttt tgaacgaatc aaagatgtaa gagaattgat tggctccaca ccctctattc
    58261 atgttcaggt gatttctcaa gattttgaag gcatcttaaa ggatgctcat gaaattcgaa
    58321 gacaagcagg agatgatata tttatcaaag tacctgttac tccagctgga ttacgtgcaa
    58381 taaaggtgct aaaaaaagag ggctaccata tcactgcaac agctatttat acagttattc
    58441 agggattatt agctatcgaa gtaggagcgg attacctagc tccatattat aatagaatgg
    58501 aaaatctgaa cattgattca aattctgtca ttcgtcaatt agctcttgct attgatagac
    58561 agaactctcc tagtaagatt ttagctgcat cctttaaaaa tgtagcacaa gtaaataatg
    58621 ctttagctgc aggtgcgcat gctgttacag caggagcaga tgtttttgaa tcagctttcg
    58681 ccatgccatc tatccaaaag gcggttgatg atttttctga cgattggttt gttactcaaa
    58741 atagtcgttc catttagata gagaggaaat acatatgaga atttttgcta gtccttctag
    58801 atatattcag ggggaaaatg ccttgtttga aaatgccaaa tcaattttgg atttgggaaa
    58861 ttacccgatt ctattatgcg atcagttggt ttatgatatt gttggaaaac gatttgaaga
    58921 ttatctacat aggtatggtt tccatattgt tctggcgcta tttaatggtg aagcttctga
    58981 caatgaaatc aatcgagttg ttgccttggc tgagaaagaa aattgtgata gtattatcgg
    59041 tcttggtggg ggaaagacga ttgatagcgc aaaagctatt gcagatttga ttgaaaagcc
    59101 tgttattatt gctccaacaa ttgcatcgac cgacgcacct gtatctgctt tatctgttat
    59161 ttatacagat gaaggtgcat ttgatcatta tctattttat tctaaaaatc cagatttagt
    59221 tttggttgat acaaaagtta tttcacaagc ccctaagcgt ttattagcgt ctggtattgc
    59281 agatggttta gcaacttggg ttgaggcgcg tgcggttatg caggcaaatg gaaaaactat
    59341 gttgggacaa cagcaaacat tggctggagt tgcaattgcg aagaaatgtg aagaaacgct
    59401 gtttgcagat ggtttacagg ctatggcagc ttgtgaagct aaagtggtga caccagcatt
    59461 agaaaatatt gttgaagcta atactttatt gagtggtcta ggttttgaaa gtggaggatt
    59521 agctgcggcg catgcaattc ataatggttt tactgcattg acaggtgaca ttcatcattt
    59581 aacacatggt gaaaaagtag cttatggaac tttagtacaa ctattattgg aaaatagacc
    59641 taaagaagaa cttgataagt atattgagtt ttacaaaaaa attggtatgc caacaactct
    59701 aaaagaaatg catttggatc aagttggata tgatgattta ataaaagttg gtaaacaagc
    59761 aactatggag ggtgagacaa ttcatcagat gccgtttaag atttcgccct cagatgttgc
    59821 tcaagctatt atcgctgtag atgcctatgt aaattcaaaa taaacaataa ggactactgt
    59881 tttccaaatg gtagtctttt attgatccct gtattgaatt ctatagcaga ttgaaata
//
LOCUS       DAVBOU010000007        59156 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBOU010000007 DAVBOU010000000
VERSION     DAVBOU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.007"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..198
                     /locus_tag="VQ879_000412"
                     /pseudo
     CDS             1..198
                     /locus_tag="VQ879_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(315..662)
                     /locus_tag="VQ879_000413"
     CDS             complement(315..662)
                     /locus_tag="VQ879_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3142635.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(773..2548)
                     /gene="spxB"
                     /locus_tag="VQ879_000414"
     CDS             complement(773..2548)
                     /gene="spxB"
                     /locus_tag="VQ879_000414"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3142636.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIVEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2755..4998)
                     /locus_tag="VQ879_000415"
     CDS             complement(2755..4998)
                     /locus_tag="VQ879_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3142637.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5008..5379)
                     /locus_tag="VQ879_000416"
     CDS             complement(5008..5379)
                     /locus_tag="VQ879_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3142638.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5390..5785)
                     /locus_tag="VQ879_000417"
     CDS             complement(5390..5785)
                     /locus_tag="VQ879_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3142639.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5969..6067
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6151..6942
                     /gene="thiD"
                     /locus_tag="VQ879_000418"
     CDS             6151..6942
                     /gene="thiD"
                     /locus_tag="VQ879_000418"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3142640.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7151..7783)
                     /locus_tag="VQ879_000419"
     CDS             complement(7151..7783)
                     /locus_tag="VQ879_000419"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3142641.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7776..8579)
                     /locus_tag="VQ879_000420"
     CDS             complement(7776..8579)
                     /locus_tag="VQ879_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3142642.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8579..9103)
                     /gene="thiW"
                     /locus_tag="VQ879_000421"
     CDS             complement(8579..9103)
                     /gene="thiW"
                     /locus_tag="VQ879_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3142643.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9108..9800)
                     /gene="tenA"
                     /locus_tag="VQ879_000422"
     CDS             complement(9108..9800)
                     /gene="tenA"
                     /locus_tag="VQ879_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3142644.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9811..10461)
                     /locus_tag="VQ879_000423"
     CDS             complement(9811..10461)
                     /locus_tag="VQ879_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3142645.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10463..11848)
                     /locus_tag="VQ879_000424"
     CDS             complement(10463..11848)
                     /locus_tag="VQ879_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142646.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11849..12409)
                     /locus_tag="VQ879_000425"
     CDS             complement(11849..12409)
                     /locus_tag="VQ879_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3142647.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12671..12759)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12968..13597)
                     /locus_tag="VQ879_000426"
     CDS             complement(12968..13597)
                     /locus_tag="VQ879_000426"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3142648.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13599..14381)
                     /gene="thiM"
                     /locus_tag="VQ879_000427"
     CDS             complement(13599..14381)
                     /gene="thiM"
                     /locus_tag="VQ879_000427"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3142649.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(14792..15331)
                     /locus_tag="VQ879_000428"
     CDS             complement(14792..15331)
                     /locus_tag="VQ879_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3142650.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(15546..15634)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15888..17024)
                     /gene="lctO"
                     /locus_tag="VQ879_000429"
     CDS             complement(15888..17024)
                     /gene="lctO"
                     /locus_tag="VQ879_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3142651.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17650..19140)
                     /gene="lysS"
                     /locus_tag="VQ879_000430"
     CDS             complement(17650..19140)
                     /gene="lysS"
                     /locus_tag="VQ879_000430"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3142652.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19268..19414)
                     /locus_tag="VQ879_000431"
     CDS             complement(19268..19414)
                     /locus_tag="VQ879_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3142653.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19641..20309
                     /locus_tag="VQ879_000432"
     CDS             19641..20309
                     /locus_tag="VQ879_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3142654.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTCHAGFGNPST
                     LSRK"
     gene            20269..20649
                     /locus_tag="VQ879_000433"
     CDS             20269..20649
                     /locus_tag="VQ879_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3142655.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            20659..20946
                     /locus_tag="VQ879_000434"
     CDS             20659..20946
                     /locus_tag="VQ879_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3142656.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            20947..21715
                     /locus_tag="VQ879_000435"
                     /pseudo
     CDS             20947..21715
                     /locus_tag="VQ879_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21727..22593
                     /locus_tag="VQ879_000436"
     CDS             21727..22593
                     /locus_tag="VQ879_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3142657.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22680..23327)
                     /locus_tag="VQ879_000437"
     CDS             complement(22680..23327)
                     /locus_tag="VQ879_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142658.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23324..24022)
                     /locus_tag="VQ879_000438"
     CDS             complement(23324..24022)
                     /locus_tag="VQ879_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142659.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24032..24784)
                     /locus_tag="VQ879_000439"
     CDS             complement(24032..24784)
                     /locus_tag="VQ879_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142660.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24784..25548)
                     /locus_tag="VQ879_000440"
     CDS             complement(24784..25548)
                     /locus_tag="VQ879_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142661.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25644..26047)
                     /locus_tag="VQ879_000441"
                     /pseudo
     CDS             complement(25644..26047)
                     /locus_tag="VQ879_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26227..26859)
                     /locus_tag="VQ879_000442"
     CDS             complement(26227..26859)
                     /locus_tag="VQ879_000442"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3142662.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26893..27594)
                     /gene="pyrF"
                     /locus_tag="VQ879_000443"
     CDS             complement(26893..27594)
                     /gene="pyrF"
                     /locus_tag="VQ879_000443"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3142663.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27827..29026)
                     /gene="divIB"
                     /locus_tag="VQ879_000444"
     CDS             complement(27827..29026)
                     /gene="divIB"
                     /locus_tag="VQ879_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3142664.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29036..30094)
                     /locus_tag="VQ879_000445"
     CDS             complement(29036..30094)
                     /locus_tag="VQ879_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3142665.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30096..31448)
                     /locus_tag="VQ879_000446"
     CDS             complement(30096..31448)
                     /locus_tag="VQ879_000446"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3142666.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(31552..32193)
                     /locus_tag="VQ879_000447"
     CDS             complement(31552..32193)
                     /locus_tag="VQ879_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142667.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32195..34215)
                     /locus_tag="VQ879_000448"
                     /pseudo
     CDS             complement(32195..34215)
                     /locus_tag="VQ879_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34286..34585)
                     /locus_tag="VQ879_000449"
     CDS             complement(34286..34585)
                     /locus_tag="VQ879_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3142668.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34951..35205)
                     /locus_tag="VQ879_000450"
     CDS             complement(34951..35205)
                     /locus_tag="VQ879_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3142669.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35225..37066)
                     /gene="typA"
                     /locus_tag="VQ879_000451"
     CDS             complement(35225..37066)
                     /gene="typA"
                     /locus_tag="VQ879_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3142670.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37228..37953
                     /locus_tag="VQ879_000452"
     CDS             37228..37953
                     /locus_tag="VQ879_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3142671.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(37993..38220)
                     /locus_tag="VQ879_000453"
     CDS             complement(37993..38220)
                     /locus_tag="VQ879_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142672.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38309..38689)
                     /locus_tag="VQ879_000454"
     CDS             complement(38309..38689)
                     /locus_tag="VQ879_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3142673.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38689..38958)
                     /locus_tag="VQ879_000455"
     CDS             complement(38689..38958)
                     /locus_tag="VQ879_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3142674.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39022..39930
                     /locus_tag="VQ879_000456"
     CDS             39022..39930
                     /locus_tag="VQ879_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3142675.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39984..40739)
                     /locus_tag="VQ879_000457"
     CDS             complement(39984..40739)
                     /locus_tag="VQ879_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3142676.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40760..41689)
                     /locus_tag="VQ879_000458"
     CDS             complement(40760..41689)
                     /locus_tag="VQ879_000458"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3142677.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41704..42327)
                     /locus_tag="VQ879_000459"
     CDS             complement(41704..42327)
                     /locus_tag="VQ879_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3142678.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42320..43558)
                     /gene="hflX"
                     /locus_tag="VQ879_000460"
     CDS             complement(42320..43558)
                     /gene="hflX"
                     /locus_tag="VQ879_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3142679.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43551..44435)
                     /gene="miaA"
                     /locus_tag="VQ879_000461"
     CDS             complement(43551..44435)
                     /gene="miaA"
                     /locus_tag="VQ879_000461"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3142680.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            44556..44726
                     /locus_tag="VQ879_000462"
     CDS             44556..44726
                     /locus_tag="VQ879_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3142681.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44774..45613)
                     /locus_tag="VQ879_000463"
     CDS             complement(44774..45613)
                     /locus_tag="VQ879_000463"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3142682.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45710..46669)
                     /locus_tag="VQ879_000464"
     CDS             complement(45710..46669)
                     /locus_tag="VQ879_000464"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3142683.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46796..47793)
                     /locus_tag="VQ879_000465"
                     /pseudo
     CDS             complement(46796..47793)
                     /locus_tag="VQ879_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47843..48460)
                     /locus_tag="VQ879_000466"
     CDS             complement(47843..48460)
                     /locus_tag="VQ879_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3142684.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALALELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKALMVGVSEELKTLDLTDIAGTCPYPTLLICGIKDKPNL
                     SSMRSLHKLISESQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48461..50182)
                     /gene="pabB"
                     /locus_tag="VQ879_000467"
     CDS             complement(48461..50182)
                     /gene="pabB"
                     /locus_tag="VQ879_000467"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3142685.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50243..55885)
                     /locus_tag="VQ879_000468"
     CDS             complement(50243..55885)
                     /locus_tag="VQ879_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3142686.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSEGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(55907..56470)
                     /locus_tag="VQ879_000469"
     CDS             complement(55907..56470)
                     /locus_tag="VQ879_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3142687.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56586..58277)
                     /locus_tag="VQ879_000470"
     CDS             complement(56586..58277)
                     /locus_tag="VQ879_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3142688.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58274..59011)
                     /locus_tag="VQ879_000471"
     CDS             complement(58274..59011)
                     /locus_tag="VQ879_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3142689.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17517 a        12989 c        10676 g        17974 t
ORIGIN      
        1 tcctccatac acaccagaga tgaacccatt gaacaagtgt tgaaagagat tcgtaaacgt
       61 ggatttaaga ataaagcctt tcgaactttg gaagatgtca tgaatcaact tcaagatgtc
      121 atacaaggac tggagaagga ggtgataaag tccatcgtta atcggagatg gactagaatg
      181 ctttttgaaa gcagatgagt attatatgca atttctttat ataaaaagac cggattgctc
      241 cgatctttca atagttcata ttctcaattt ctattttaaa aatagctaag gttaacgtca
      301 aatgactacg cgacctattt catacgataa aaatcaagca ctagaccagc aggtccttga
      361 actaataagg actctgttcc ccaatcggtt acagttggtc cgtgtaaaac ctttatacca
      421 agctcgttca accgtttgta gttctggtct acatcctcaa cctcgatatg aataatgatt
      481 cctgactgaa agttttccaa aggaaccaaa tgattttgtg acaacataag gcagtgacta
      541 ccaatcgtaa actgagcaaa accatcatca gcataatctg cctttttatc caagatatgc
      601 tccaagtcag cacagacttg gggaacattt gaaacgataa tatctaattg atttaaattc
      661 atttactctc ctccataaaa agaccggatt gctccgatct tttaaagttc tgctctatga
      721 aaatcaaaga ataaagtcta caagtttcat atttgatttt cggcgagagg aattatttaa
      781 ttgcgcgtga ttgcaatcct tcttcttcca agaagagacg gaatggtacg agttcttctg
      841 cttcgtattt ttccttgaag gctttgatag cttcttctga gtgaagtttt ggatccaatt
      901 caagtacttc tactggaagt ggacggtgtt gagtgatgcg agcatcgatg acaacagttt
      961 taccttcttt gttcaattta acagcttctg caacaactgc atcgatgtct tcgatacggt
     1021 caactgtgaa tccaacagct ccttgagctt ccacaatttt agcgtagtca gcgtttgtga
     1081 agtctacacc aaacaagtgt ttgtttgtat cttcgtattt gttcttgatg aagccgtact
     1141 cagcatttga gaagacaagg ttgataactg gaaggtcgta ttgaacgttt gtgataacgt
     1201 ctgggtagca catgttgaat gctccgtcac ccatgatgtt ccatacttgg cgatctggat
     1261 tgtctttctt agcagcgata ccaccaggaa gggcaatacc cattgtcgca aagagtggag
     1321 atgtacgcca catgttctta ggtgtcatgt gaaggtgacg agtagatgtt tgagtagtgt
     1381 tacctacgtc gattgagtag atagcgtctt gatcagcatg tttgttgatt gcattgtaaa
     1441 cttgatacaa ttgcaattca ccctcagttt taccttcgag tttgttcatg taatcacgcc
     1501 agttttgatt gttcttaacg tttgcacgcc accatggagt tgattcaact gggtttactt
     1561 tgtcaaggat agctttagct gcttgaccag catcaccaag gattgaagcg tcaagggcat
     1621 gacgtttacc aagtttgtaa gggtcgatat cgacttggat gaatttttca gtgttcttga
     1681 atgcttcgta aacttcagcg aatgggaagt ttgaaccaag gaaaagaact gtgtctgctt
     1741 caaagaccac ttcgttggct ggtttccaac caacacggta agcagaacct gtcaaacctt
     1801 catagttcca ttcgaaagct tcaaagtttt taccagttgt gatgattggt gctttgattt
     1861 tacgtgacaa ttcagtaatc acttcaccag ctttaacacc accaaatcca gcatagataa
     1921 ctgggcgttc agcattgttc aagatttcaa cagctttgtc gatttcaact tcgttcaaag
     1981 caggagcgat gaatgagcgt tcgtatgaac ctgaaccgta gtatgagttt tcatcgattt
     2041 cttggaaacc gaagtttact ggaatttcaa caacagctgg acctttttta gaaactgcag
     2101 cacggcaggc ttcgtcaatt acttttggca attgctcagc gtaagctaca cgtttgttgt
     2161 aaacagcgat accgttgtac attgggtttt ggttaagctc ttggaaagca tccatgttca
     2221 attcgttaac tggacgtgat ccaaggatcg ctaggaatgg agtgttatcc atagctgcat
     2281 cgtaaacacc gttaatcaag tgagtcgcac ctggaccacc tgaaccaact gcaaccccga
     2341 ttgagccgcc gaatttagct tgcataaccg ctgcaagagc acctgtctct tcgtggcgaa
     2401 cttgtaagaa acggatatct ttgtcttcag ccaaagcatc catcaatgag ctgagtgttc
     2461 ctgatgggat accgtagatt gtatctacgc cccatgtttt caatacgtta agcattgctg
     2521 cagatgcagt aattttccct tgagtcataa tgataactct ccttcaattt ttttaaactt
     2581 ggagaatacg attacataga attggaaacg ttctccaaat ttttactatt ccactgtatc
     2641 atatttatgc tgacttttct aaaaatctgc tcaaaactct ctattctcta ttctaataca
     2701 gttttgaaag tgttgtcatt tctgttttat aacaaagaaa tctagtcatt acttttagtc
     2761 tattttacta aaatttaaca gaagggaact ggtcagaaca gatacagaac taaaggccat
     2821 ggctagacct gccaattctg ggttgagagc cagtccaaca cctgaaaaga ctcctgctgc
     2881 aatcggaatt ccgacaacat tgtagataaa agcccagaaa agattgagta gaattcgatg
     2941 aaaggttttc ttactcatat caaaggcacg aaccactcct aaaagattat tggttgtcaa
     3001 caccaaatct gctgactcga tggcgatatc tgttccagct cccatagcaa tccccacatc
     3061 tgctacacta agggcaggag cgtcattgat accgtcccca acaaaggcta ctttccctga
     3121 ctgttgcagt ttatggattt catgggcttt ttcttctggc aagacgcctg caatgacctc
     3181 ttcaattccg atttgatctg caatagcacg cgccacacca gcattgtctc ctgtcagcat
     3241 gactgttcgg agaccacgtt tttttagctg actgatgact agcttagcat tttccttagg
     3301 aatatcttgc aaagcaagca agcctttgat ttcattgtca acagctaaga acacaactgt
     3361 cttagcttct ttttctagtt cttctagttt atcttgataa gtattagaaa tatccatgcc
     3421 atccagcatt ttagcatttc caagtaaaac ttgttttcca ttgattcgcc ctgaaacacc
     3481 tttcccgtgc aaggcctgaa aattttcaac agtttgaaac tcaagtccag cttcactcgc
     3541 tcgcttaacg atagcctcag ccagtgggtg ttgagaagca tcttccaagg aggctgccaa
     3601 tccaaacact tctacttcgt cgccgatgat atctgttacc acaggtttcc cttccgtcaa
     3661 agtcccggtc ttatcaaaga caagagtttg aactttctgg atttcctgta agacagttcc
     3721 atttttgagg agaaccccca tcttggcact acgtcctgtc cccaccataa gggctgtcgg
     3781 tgttgcaagt cccaaggcac aaggacaggc gataatcaaa accgccactc cgtagagaag
     3841 agaggacaca aagctagctc caagcacgac cacactatcc ctgagcaaga cgaaccaaac
     3901 ccaaaaggtc atgattccta aaatgacaac tactgggaca aaaatccctg aaatcttatc
     3961 cgtcaagtcc tgaatcggcg cacgacttgt ctgagctttc ttcacaaaat ccacaatctg
     4021 agccaaaaca gtctctgagc caactttttc tgctctaaag acaagcgttc cactatgatt
     4081 gatggttgag ccaatgacag tatctccaac tgtcttgtcc acaggcagac tctcacctgt
     4141 caccatggat tcgtcaatac tagagacacc ttctactacg acaccatcaa cagcaatctt
     4201 ttcaccggga cgcactcgaa tcaggtcgcc taccttgact tgttccaaag gaacttggac
     4261 ataactatca tcactcaaga cttctgcggt tttagcttgc aagtccagta atttctccac
     4321 agcttgggac gtattttttc tcattttttc ctcaaaaact gctcccaaaa gaacgaaaaa
     4381 gaggataaat ccagcacttt cgaagtaaac agggagacca gcaaagagag caactaggct
     4441 atagaaataa gccactagag ttcccagcgc aaccaaggta tccatgttgg cattgtgctt
     4501 tttaaaactg gcccaagcac tctggatata tggcttacct gcaactaaca taataggcgt
     4561 tgttgctaga aaggttcccc aatgcatgac ttgatgacta atgctacctg tcaacatccc
     4621 aatcatgaga atcacaagag gcacagtaaa gatactagta atccaaaaac gttgcaggag
     4681 agatagagat tttcgagtct tctcaacgac tatatagctt cccttttgca tcttcatgcc
     4741 acaagaaaat tcatgtcgcc ctaattcttg aggtgtaaaa cgaatgactt tctcctcatc
     4801 tacgccgatt ggttccaaga taccttcttc ttcaaacaga atttccttat aacagtttga
     4861 aggagtagca cgatgaaagg taatctcagc tggaattccc ttttgaagct ggatatgggc
     4921 tggatgatag cctttttcag ctcggatacg gattttttga atgccatttt ctaagcttgc
     4981 tttcacaatt tctgtcatag tctccaccta ctctacaatc atcttgccgt gcatcatgtt
     5041 cataccacaa gcaaagccaa actctccaac ctgctcaggc gtgatttcca ctacatactc
     5101 ttcccccatt ggcaggttcg catgtacacc aaaatctgga aaaacaattt gatccagaca
     5161 tggtgaagga tccttgcggt caaagacaat gcgtgctggc actgatttct tgaggacaat
     5221 caactcagga gtatagcctc ccatgacttc cactcgaatc tcttggtatc cgtttttttg
     5281 ctgggctttt tgtccagatt tttcaggctt tttgaaaaac caaaacaaga taaacgcgat
     5341 aagggcaata caaataatgg ttacaatact atttaacatg gcgtctcctt tacatacaat
     5401 tacatcttac ttctgttaca gcacttgatt tcttctctga aatcacagct tccaagtctt
     5461 ccaagtcagt ctgagtaaat tcacattcta caatcaagtc agccaacaaa ttcctaatcc
     5521 tacgggaaca aaccttgtct ttgatatctt ggacaagtaa atcccgactt tggtctagag
     5581 ttaaaagcgc tgaataaaca aaggacttgc cttctttttt ccgagtcaga cactctttct
     5641 caaccaaacg agccaaaaga gtttgaatgg tcgacttgga ccagtcgaac cgctctgcca
     5701 aaaccctaat caaatctgta ctggtctgct ccccctgcat ccaaataatc ttcatgacct
     5761 gccattctgc atctgaaatc tgcattacca tacctccaaa atctacattt gtcaattaca
     5821 ctcatcagta tactcttaaa atctacattt gtcaattata gaaataatat tttcttcgaa
     5881 aaatagaatt ttaatcattt gaaaaacgat ttgcagtcaa atattactat ataaacaata
     5941 aaaatatgct atactaaaga aaaaagaaaa caaccactag gggtgcgtaa agctgagatt
     6001 aacgactgtt agatccctct gactcaatct aggtaatgct agctgatgga agtggaaatg
     6061 ataatgggga ctagcagtct tctattgcct ttctaaaaca gactagcttg ttcttaagaa
     6121 tacaaacttc agttggttgg gaggttttag atgacttatt tacccgttgc tttgaccatt
     6181 gcagggactg accctagtgg tggtgctggc attatggcag atttaaagtc attccaagcg
     6241 agagatgtct atggaatggc tgttgtaacc agtcttgtcg ctcaaaatac cagaggtgtt
     6301 cagctaatcg agcacgtttc tcctcaaatg ttgaaagccc aattggagag tgtcttttct
     6361 gatattccac ctcaggctgt aaaaactgga atgttggcta ctactgaaat catggaaatc
     6421 atccaaccct atcttaaaaa actggattgt ccctatgtcc ttgatcctgt tatggttgct
     6481 acaagtggag atgccttgat tgactcaagt gctagagact atctcaaaac aaacttacta
     6541 cctctagcaa ctattattac gccaaatctt cctgaagcag aagagattgt tggtttttca
     6601 atccatgacc ccgaaggcat gcagcgtgct ggtcgcctga ttttaaaaga atttggtcct
     6661 cagtctgtgg ttatcaaagg cggacatctc aaaggtggtg ctaaagattt cctctttacc
     6721 aagaatgaac aatttgtctg ggaaagccca cgaattcaaa cctgtcacac ccatggtact
     6781 ggatgtacct ttgctgcagt gattactgct gaactagcca agggcaagag tctttaccag
     6841 gcagttgata aggccaaggc ctttatcaca aaagctattc aagatgcccc tcaactcggt
     6901 catggttctg gtccagtcaa ccatacaact tttaaagatt aagaaaaaaa ctctctagtt
     6961 cccactttaa gggaattaga gagtttttat actcttcgaa aatctcttca aactacgtca
     7021 gcttccatct gcaacctcaa aacactgttt tgagctgact tcgtcagtct tatctaaaac
     7081 ctcaaggcag tactttgagc aacctgcgac tagctttcta gtttactctt tgattttcat
     7141 tgagtattaa ttaggaaaga atgtcatgca actttgttaa aaaggcttgc gtttttgcct
     7201 caatatcttc tgcttgcatc aaatcacgta caacagctac accagctatg ccagtgccca
     7261 taagctgatc aatattctcc gaagtcaagc ctccaatagc aactactgga atggcaaccg
     7321 tttggcaaat tgttttcaag gtcgatatca gagtaatggg cgcattttcc ttggtggtgg
     7381 ttgggaaaat ggctcctgta cccaagtaat ctgcacctga tttctccgct tccagagctc
     7441 ttttaaccgt tttagcggtg acaccgagga ttttttcagg acccaagact ttgcgagcta
     7501 ccgaaactgg taattcatca tctccgatat gcagacctgc tgcatcaacc gcaagacaaa
     7561 catccaaccg atcatcgatt atcaagggga cctgataggc atctgttatt tccttgactt
     7621 gttttgccag ttgataatat tgattggttg tgagattttt ttctcgcaat tggactatgg
     7681 taacccctga acggcaggcc gtctcaactt ttgcaagaaa gctttccacg gaatcttgat
     7741 agcgattggt taccagatat agtctaagtg cttctctatt cataaacctc tcctttgatg
     7801 gtatctagcc aattttcatc tcttcttagg agcgaaagct gattgagtac ttggtaacga
     7861 aattcttcca atcccattcc ttgaacaact attttctcag cagcgatatt gagataagag
     7921 actgctaagc aagaagcttc aaaaccagtc tttccttggc tgagaaaaac ggctgttaag
     7981 gctccaacca agtctcctgt ccctgttatc cagtctaatt cagtacagcc attctccagt
     8041 acagcaactt gattctccga aacaataagg tccttggggc cagtaactaa gaaagacata
     8101 ccaggatagg tctgacacca gtctttcaag acttgaagca aatcctccgt ttcttgatct
     8161 ttagcactcg catcgacccc aacgccgtgg tgctttaatc caacaagact tcgaatttct
     8221 gacatgtttc ctttaaggac cgtaggtcta tagtctaaaa ggtctttaac taagctctta
     8281 cgaatggatg aagtcgttac gccaaccgca tctactacca tcgggagaga agattggttt
     8341 gcatacgaag ctgccatgcg gattgctttt tccttctcag ctgacaaatg ccccaaattg
     8401 atgaagagag cctgactttg cttagtaaaa tcaagaactt cacggggatc atctgccatg
     8461 acaggtttgc atcccagagc caaaatccca tttgccagca tctcacaaga aatctcattg
     8521 gtcatacagt gaatgaggga actagagcct ataggaaaag gatttgtcaa tgcctgcatc
     8581 attctatcct ttcagcaaag aaatatcctt gcactttttt aaagaattcc tgcttgatta
     8641 aaaatctaaa tgcaataaag gaaatcgctg taccaatcaa ggttgctccg aaaaatcgag
     8701 gagtgtagat aaaccaacta agcttagcag ccgatcctgt aaagagcacc ataacaggat
     8761 aggaaacaat agaaccaata atacctgttc ccacaatttc tcccaaggca gaaaagtaaa
     8821 attttcgacc gtacttataa aagagacctg ctagaagggc tccaaaagtc gctcctgtga
     8881 gagctaaagg cggaatccct tgagtcgtca tacggataaa ggctgtcact gtagccatag
     8941 ccaaggcata aacaggtccc atcatgattc ccgctagaat attgactaca ctggacatcg
     9001 gtgccattcc ctcaatccga aagataggtg taaggactac atcaagggca atcatcatag
     9061 ataaaatggt caatttgtga acttgtagtt ggtgctttct catgtttcta ttcttctcct
     9121 ttttctaaag actgtaaatc gctcttccat gtctggtgtt ggtaagccat ctcccaaaac
     9181 ttagcttcca tatgaacact gatgtggaag gcatctagca ttttttgctt atctgtctca
     9241 tcactttctc gataaagctg attgaccagt gctccctcct ctctgatctg ttgctctaac
     9301 tcatccgtaa tataagtttc aatccattgt tgatagagag gatttggtga tggtttaaga
     9361 ttaagtgatt tgcctatatc atggtataac caaggacaag gaagcaagct tgcaaaagct
     9421 atggctaagt tcggttctgc aaattgccta taaatatgag aaatgtaatg ataacaggtt
     9481 ggagcgattg gatgttgctc catttcctgg tcgttgattt ccaattcctt gaaaaattgt
     9541 tggcgaataa ataactcacc ctccactaaa ccctgagcat tttgtttcaa gagtcttttc
     9601 atctcttggt ttgaagtctt atcagccaaa agatgataga tttctgagaa agccttcaga
     9661 tagtaggcat cctgaatcag gtaatagcgg aaaatggcag gttctaaatt cccctcttgt
     9721 aattgtaaaa taaagggatg atgaaaggaa gcctgccaag ctttcttgga taattccatc
     9781 gcaatatctg taaattccat aataactcct ttataaaaat agactggttt gaagcaataa
     9841 aaagaaaagc aggtagatta attttgtttt tttaggaata taaaaagtcc gatagctatt
     9901 cttcaactgt gcatgttcgt catatccgtg agcagataga gctctcaggt aaagatggcg
     9961 ccacctaaag actgtcatca gaaccttact gtaaatcaag ggcgaccaaa aatgtagttt
    10021 ttgaccacgt aataggcaag cttctttgag ggacttgatt tcttgctgaa tgagaggaaa
    10081 agaattgaat accacaatca aggcatagga ccaagagcgt gatagcccct tttgagccaa
    10141 gtacaagaga agctctttta gtgaaataga ggaaacaaag acaaggccga tacaaactgt
    10201 cacaaaggcc ctcgttccaa gcatgactgc ctgtgaagca tctccgtgta actgaactgc
    10261 ccagtagttg gcaaaagatg gtaaaatggc aagtatgatc atccaagcta acattttaaa
    10321 tcgacggtaa tagagcataa agagaataca aaatgcgact accgaaagat tcagagcaat
    10381 cgaaggaatg aaagatgttt ccaaggataa aatcagcaag aagagactga taatcggtgt
    10441 ctgggttgct actttgacca tactatctca cctccccttg ggtattgcta ctctgagatg
    10501 taagtggttt ggtaatggtc acttctttca catgccgaag accctgacta gtcatctcaa
    10561 tccaataatc aaccacagaa atcaaagggt ctaaacgatg actaatgagc agaaaacttc
    10621 ttccttgatt cctctcctcc acaatccact tgcaaaaata atggcaggct ctatcatcca
    10681 aacctgcaaa aggttcatct agcaagatca cggaagcctt actggtcaag atggtcagga
    10741 gctgaagaat tttttgctga ccaccactta attgataggg actcttatcg actgcctgct
    10801 ccaaatcaaa atatcgtaaa gcttgaaaaa tccgctgatt tctttcagaa tcaggtccat
    10861 ctaattgaag ctcctctcgc agactgactc ggataaactg cttctcagct tcctgaacaa
    10921 cacccgtcag atcacggtac aaactctttt tctttttcag gactgtcccc ttccatgcaa
    10981 tgcgcccctt atacttttga aattgaagaa tagaccgaaa gagggttgat ttcccgacac
    11041 cattgtcacc caggatacag gaaatccctt gatagaatgt gaaatcagca attgaaaaga
    11101 gggggcgatt accaagctca ccagtcacac ggttcatatg gaataattcc gggctagaag
    11161 caacttcctt tgaagcaacc tgtgtcatct cataggaagg gatttgattt atttccctta
    11221 gttttccgtc tcttagctca accatatggt cgatataggc tttatagtca gataaatcat
    11281 ggtcgcacaa aataactgtc ttcccatcaa gagccaactc ttttagaatc tccaatatct
    11341 cgattctgct cttgcggtca atggaagcga agggctcatc caagagatat accctaggat
    11401 tcatggcaaa gaggacagcc agcgctgctt tttgcttttc cccacctgat aggtgatgaa
    11461 tgggacggtg taagattgcc tcgcaacgac attgctggac aacctctgct attttagaat
    11521 caatttcctg aaggtgatag ccgatattct ccaaggtgaa aatcaactcc tcaaacaagt
    11581 tctccatggt aaattgatga ttgggatttt gcaagagaat gccaaccttc tggacacgtg
    11641 cgatgataga aagctgactg acctcgctcc catctatcag gacttgacca ctatagggaa
    11701 gagaactgac ttgggcaatc atttgaaaga ggctggattt tcctgaacca ctgctcccaa
    11761 ctaacaaggt aaaggcttgc gcatgaaaag taaaatcaaa cggctcagag aagattgggg
    11821 actgaatcgc tcgtagttcc agacccatct atgcttttcc tccagttgca aactgatgat
    11881 agagtttgac aatggcacga accaagatgg tacagaagaa ataaacagaa ataaaacgta
    11941 ccacaagcaa ggaaaggaca aacggaaggg aaaaggcgta gtaacctaac ttaatgtatt
    12001 catagacaaa gctaacaagc gtaatcccaa tactattagc agttagagag agccaacttt
    12061 catagcgatt cttagttacg ataaaaccaa attcacttcc caaaccttga accaagccag
    12121 acaaaagagc tcctagacca aattggctac cataaaggac ttcagcaagc gcagctagca
    12181 cttctccaat cgttgcactt ccgactctcg gaacaaagat ggcagcaatg ggcgcagcca
    12241 tacaccagag accgaagagg atttcattgg caaaggcctg caaaccaaga ggtgttaaga
    12301 gtagactgag aatattatac acatatcctg aaccaacgaa aaccccacca aaaaagatag
    12361 acaagaaagc aagcaagata acatctttta actgccattt tttcaacata aaaaactcct
    12421 ttttttaaag aaaagtgggg cactcaagaa gaccgaccta aatactttgt atagcagact
    12481 gaatttagaa cagtacacaa gaacactaaa atatttctag aaattaattt gaattttcta
    12541 attgatttgt tcgcatctta tttcaatcta ctatatcatc ttcatccagt ttcgtaaaag
    12601 aaaaaactct aattacagat acgaattaga gttcagctta caagattaga cagttctttt
    12661 cgacatacga aaaaaacatt tcacatttcc cttcgccagt cttaactgta tcaggttcaa
    12721 tgggtatcat ctcagcctaa agcaccccaa atgcctttat tatttaatta tgtgattatt
    12781 ataacacaca ttttatacta gttcaagaaa ttgaactgga aatacagcct tgcactcaca
    12841 aagacagcag atctttcttt tgcaaaaaac aaatgacctg tttgatgaat tagctattca
    12901 agctgaatct agacatagct ttttaaaaaa ggaaaatcct acttacttag aatccaagga
    12961 tagatatcta ttgttcactc atttcccgaa cagttttttc tatatttttt gcatacgata
    13021 ttgccgaaat gattgaaacg ccgtcaacat tggtctttat aatgtcttta atatgtttcg
    13081 tctgtatccc accaattgca actaaaggca tttgtggcaa tagttttctc atcaattcaa
    13141 gaccttcata acctatagca ccaccagcat catcctttga ctgggtatca aatacaggac
    13201 caacaccaac ataatctaca tattcaactt ttgattgttg aaattcttcc tcgtttttta
    13261 tagaaagacc aattatttta tctggcatca attttctaat ttcatcaaca ccaatatcat
    13321 cttgacctac atgtacgcca tcagcgtcaa tttccattgc taaatctata tcgtcattaa
    13381 cgataaatgg aacattgtat tttttacaaa gttctttaat ttggatagct agctcaagtt
    13441 tttctaagcc ttctaaagca ccctcacctt tttctcgaaa ttgaaataag gttataccac
    13501 cttttaaggc ttcctcaacg actgtatata gattttttcc ttggcaagta gtcgttccac
    13561 aaataaaata tagttttagt aattctttat gaaacatctt acttcactct tttgaatttc
    13621 ttgacatctt catctgtaat ttcatataag gcatttataa attcaacttt aaatgttcca
    13681 ggaagatgtc catttggacg tttttccgcc atttctccag cgatattgta aaccaacatt
    13741 gctgtttcta atgatttcaa ttcttgacct ttttcaagtc cgataaagct tgctactaca
    13801 gctcctaata agcatcctgt cccaatgact ttcggcatca tagcactacc attatgaatc
    13861 gttaccactt ctccattaac agcaatggca tccacttcac ctgttactac tattggaata
    13921 ttgaacttct catttgctgc tagagcaatt tcgtcaatat tatctacgcc cgcactatct
    13981 actcctttag atgccacatc tattcctact aaagaggcaa tctctccagc attcccccta
    14041 atcgcagcta gtttgtaatt gttgattaaa tcatctgcta ctttttttct atattctcct
    14101 gctccacagg ctacaggatc taaaactgct gggacattat atttctctgc aattttcaga
    14161 gcagcttggt ataatttcca attttcatct gtcaatgttc ctatgtttat taataaacca
    14221 ccagcatact ttaataagtc ctctaaatct gctggaaact cactcatggc tggtgaggcg
    14281 cccagtgcta ctaatccatt tgctgtgaaa ttttttacta catcattggt gatgcaaatg
    14341 accaaaggtg ctttttcttt taataatttt aaacttgtca tattgaaatc cttccttttc
    14401 actttatacg atctactaat ttcgatttat ctttagttga gaattttttt catttacatt
    14461 gaatgattta tactcaatga aaatcaaaga gcaaactagg aggctaaccg caggttgctc
    14521 aaaacactgc tttgagcctg tagataagac tgacgaagtc agctcaaaac actgttttga
    14581 ggttgtggat agaactgacg tggtttgaag agattttcga agagtcttac ctcatcaaat
    14641 ttgtaaatat catgagcctt ctctagacat cgtaaccaat atcaaaaaaa gctaattcta
    14701 aagcgactgc ttgattccag cgttgctgaa gttctgtcaa atcttctcga tttttaccga
    14761 cacgattgag ttcatcaacc agaaattgaa ctcactctgc aaagaaagga cctctgtgga
    14821 gattgatcca ttccgaatga atatagactt caggtagagc caaatcttta gaaccccagt
    14881 ctaaatagag accttctgca atgaccagca taaccaaaag atgggcatag tctgatgaag
    14941 ccactgccca atacattaga tcctgaaagg cttttgttac agggtgcaaa gtcacttcta
    15001 gatagttatt ctctgctact tttaactctt taaaagcctt ttggaaataa ccatcttcat
    15061 ctgcttcaag aaagcctagt tgcttggcaa aacgaagctt ggattcaagt ttatctgcgt
    15121 gagctacgca ggcacccagc atggataaga aggcatcaaa gaagtgataa tcttgaatca
    15181 gatagtcctt taagacctta ttctcaattg tccccgcaaa aagttcctta acaaaacgat
    15241 gattgattgc agcctgccaa tccttctgac tgctttttaa taattctcca acagtcaaac
    15301 ctggctgaaa tgcatagtct tgtgtttcca tatttacttc tcctctcttt acttgttagt
    15361 aattaataaa acagcaagaa atatcaagca aaatcgtaat tccacttgat ccttttaaag
    15421 cacatcgaga gcatttacag agagctaact aaacaagcct atccagttta tataaacaaa
    15481 aaactccaat tacaatcaag aattagagtt gacttacaag attagaccgt tcatttcacc
    15541 atacgaaaaa actgttcaca tttcccttcg ccagtcttaa ctgtatcagg ttcaatgggt
    15601 attatctcag cctaaagcac cccaaatgtc tctattattt aattactgaa ccagtatagc
    15661 aaaaaatgaa agccctagca agatatttga ccgaaaaata tctttatata caatatattg
    15721 aaactagaat agtacacctc tacttctaaa acattgttag aaatcgattt aactgtcctg
    15781 attgatttgt cctattctta tttcatttta ctatagtttt cgatagcgat ttattcttcc
    15841 aatacacgaa gaaaaacctc cacattcagt gaaggcaatc tattttatca atacaatttt
    15901 aagtcacgag ggtcaactgg gaaggttggg ttgtatggat tgtgacggag cttaaagtgt
    15961 ttgacatctt caatggtctg agctccagac aattgcataa ctgtcttcaa ttccgcattc
    16021 aagtgttcaa agacttgacg cacaccgaca ctaccaccga gagccaagcc ataaataaca
    16081 gggcgaccaa tagctaccaa gtctgctcct gaagccaagg ctttaaagac gtgttgacca
    16141 cgacgaacac cagagtcaaa gacaatcggc acacgtctat caactgcttc tgccacttct
    16201 tgaagcgagt caaaggcagc tggtccaccg tcgatttgac gaccaccgtg gttggttacc
    16261 cagataccag aagctcctgc agcaagtgaa cgttcaacgt cctcacggca ttgtggtccc
    16321 ttgacataca caggaagacc agagtattca gcgataaatt ctacatcgcg tggagacaag
    16381 cgttgtttag ctgatttgta aacaaagtcc attgatttac cagcaccttc tggcaggtat
    16441 tcttcaacaa tcggcatgcc aactgggaag acaaaaccat tacgcttatc cacttcacga
    16501 ttccccccta cagtagcatc tgccgtcaag acaatcgctt tataaccttc agccttcaca
    16561 cggtccatga tgtggcggtt gataccgtca tccttactaa agtaaaattg gaaccaatgg
    16621 ggtgtccctt gaagggcttc agaaatctct ggaaggtcaa cagtagagta agagctggtt
    16681 gtataaagag aaccaaactc atgcacacca cgcgcagtcg ccacttcccc ctgttcattt
    16741 gccaatttat gagccgcaac aggcgccata atgattggtg aagatagttt ttcacctgca
    16801 aattcaatct ctgtacttgg attttcaaca tcgcaaagtg tatgaggaac gatgagtttg
    16861 tggttaaagg cgcggatatt ctctcttaaa gtgaaagtat cttccgcccc actagcgata
    16921 tagccaaatg ctgctttagg aataacttgt tgcgccattg gctccaaatc ataggtattg
    16981 atgaagtcta catgaccttc tgcattgctt gttttatatg acataaaatg ccctccttga
    17041 ttaagtaagc gtttgctttt tactacacaa ctataataac tcttttttca atcattttca
    17101 agagttttgc ttaaaaacca tcttattttt tcatacaata tactagccct actttcctta
    17161 aactctaaac cttagtctat attaagtgaa tcgttgagat tttttgctgc caggcatttg
    17221 aactactttt ttatttgcgg attctatcta ctaatactat aaaaaaaaca agtgaataag
    17281 acaccagaac atcctctaat aggacctatg gacttatatc agtcccatat atactgttta
    17341 agcaagatac tatcctagtt gacgctaact tcctatccca cttattaatt ttttatttat
    17401 agtgaatctg aacaaatcaa ttggggaatc caagtcaatt tctagtactt tttgaacagt
    17461 ttcagcgtac tatcgtaaaa tgaaataaaa catgcacaaa ttgattaggg aatttaaacc
    17521 aatttctaac aatgtcttag aaatcaaagt gtactatttc aacttcaata tactacactt
    17581 cattttctcc ttaaattcag tctctttttg aatcaaaaaa tcctctggta agagccagag
    17641 ggtaagaatt tatttcattg ttgggaagag caatacatca cggatagttg ttgtatcagt
    17701 gaggagcatg cagagacggt cgataccgat tcccaaacca cctgttggtg gcataccgta
    17761 ttcaagagcc tcgatgtagt catagtcgat gcctgtcgct tcatcatcac caagttcttt
    17821 agctttagct tgggcttcaa aacggctaag ttggtcgatt gggtcgttga gctcagtaaa
    17881 ggcattaccg tactccttag tcatgataaa gagctcgaaa cggtcagtaa agcgttggtc
    17941 ttcaggattt ttcttagcga gtggagatac agctactgga tgtccataga caaaggttgg
    18001 ttggattaaa gtttcttcaa caaactcttc aaagaaggca ttgatgatgt gaccaacctc
    18061 agtgtagtgt ttctcaactg gaactttctt ctcagcagcg atagctttag cttctttcaa
    18121 agtcatgtct tgccagaaat cgacaccagt aatttctctg atagcatcca ccatatgaac
    18181 acgcttaaat ggttcgttaa tcttgatttc agtaccttgg tagttgactg ggccatcgcc
    18241 cttaactgat ttagcagcat gttggataat gccttccgtc aagtccatga tatcttggaa
    18301 gtctgcataa gcttggtaaa cttcgataga agtgaactca gggttatgag tagcatccat
    18361 tccttcgtta cggaagatac ggccaatttc atagacacgt tccataccac ccacgataag
    18421 gcgttttaag tgaagctcag tcgcgatacg aagcaccatg tcaatgtttt gggcattgtg
    18481 gtgggtgata aatggacggg cagcagcacc accggcttca ttatgaagaa caggtgtttc
    18541 cacttcaagg aatccttttt ggtcaaggta acgacggatt tcagagatga tttttgaacg
    18601 agtgacaaag cgttcaaagc tttcacgatt agaaatcaag tcaaggtaac gtttacggta
    18661 aattgtttca acgtctgtca aaccatggaa tttctcagga agaggacgaa gagccttaga
    18721 caagtgtgtg atgtgggttg ccttgataga gagttctccc atatccgtac gcatcacttc
    18781 accttcgaca ccaaggaagt caccaaggtc tgcttttttg aagatttcgt agttttcttc
    18841 accgacagca tccttacgaa cgtagatctg aatctggcct tcgcggtctt gaaggtgggc
    18901 aaaaccaact tttcctttac cacgtttggt taccaagcgt cctgcgatag tagctgtttc
    18961 gtttttatcg tgtaattgtt ctttatcgag gttggcatat ttatctttta attcttgtga
    19021 atttgcagta cgttcaaaac gttttccgaa aggatcgatt ccttgttcgc ggagcgcagc
    19081 cattttttca cggcgaacga tctgctggtc atttagttct tccatatgtt ctgtagacat
    19141 gggatcctcc tagttttact caaaattgaa tacgatgagt cattttttgc gatactccca
    19201 ttttatcata aataagcaag aaattcacgg ataatcttta aaaactaaaa agaacctgac
    19261 gctaaaatca ctggaaagaa gtgaaagtat cttccgcccc actagcgata tagccaaatg
    19321 ctgctttagg aataacttgt tgcgccattg gctccaaatc ataggtattg atgaaatcta
    19381 catgaccttc tgcattgctt gttttgtatg acataaaatg tcctccttaa taagtaagcg
    19441 tttactttgt atattataaa aatatattaa ctcttttttc aaaacttttc aaatattttg
    19501 tttggaaatt tcagaaattt tatgtctatg ataaaaatcc ttataacggc aataaaaaat
    19561 agatattatc caaagaagat tttaagtgct acaataactg tattatttct agatgggagg
    19621 ttctattttt ggattgatcc attgttgaac aatatctacc actatatcaa aaggcattct
    19681 ttctgacctt gcatattgca gtttggggaa ttttgggatc ctttctgctc ggtttaatcg
    19741 ttagtatcat ccgacattat cgaatccctg ttttagcgca agtagcgaca gcctacattg
    19801 aattgtcacg taatacgccc cttttgattc aactcttctt tctctacttc ggtcttcccc
    19861 taatcgggat tgtcctatct tcagaagtct gtgcaacgct tggacttgtc tttttaggag
    19921 gctcctatat ggcagaatct ttccgaagtg ggctggaagc catcagtcaa acccagcagg
    19981 agattggcct cgctattggt ctgacacctc tacaggtctt tcgctatgtg gttcttccgc
    20041 aagcaacagc ggtggtactc ccctccttta gtgccaatgt cattttcctt atcaagaaaa
    20101 cctctgtttt ctcagcagtg gctttggccg acctcatgta cgtcgccaag gatttgattg
    20161 gtctctacta tgagacagac attgcgctag ctatgttggt agttgcttat ctgatcatgc
    20221 tgctacccat ctcactggtc tttagctgga tagaaaggag gacctgccat gcaggattcg
    20281 ggaatccaag tactctttca aggaaataat ctcctgagaa tcttacaggg gttgggcgtt
    20341 acgattggga tatccatcct gtctgtcctc ttatccatga tgttcggaac agtcatggga
    20401 atcatcatga cctcccattc tagaatcata cgatttttaa cacgattgta tctggaattt
    20461 atccgtatca tgccccagct ggtgctactc ttcatcgttt actttggctt ggctcgaaac
    20521 tttaatatca atatctcagg tgagacttca gctattatca tttttaccct ctggggaaca
    20581 gctgaaatgg gagacttggt acgtggagct atcacttctc tccctaaaca tcagtttgaa
    20641 agtggatagg cactcggctt gactaatgtt caactttact accacatcat catcccacaa
    20701 gtcttaagaa gactgctacc gcaggctatc aatcttgtca ctcggatgat taaaaccact
    20761 tcattagttg ttttgattgg ggttgtggaa gtgaccaaag ttggacaaca aatcatcgat
    20821 agcaatcgcc tgaccatccc aactgcttca ttttggattt atggaaccat tctagtctta
    20881 tatttcgcag tttgctaccc tatttccaaa ctatccactc acttagaaaa acattggaga
    20941 aactaaatgt ctgaaactat cttagaaatc aaggaactaa aaaaatcctt cggagacaat
    21001 cccatcctcc aaggactttc tctagaaatc aaaaaagggg aagttgttgt catcctaggg
    21061 ccatttggtt gtgggaaaag taccctcctt cgttgcctca acggcttaga aagtattcaa
    21121 ggtggagata ttcttctgga tggtcagtct atcgttgaaa ataaaaaaga ttttcaccta
    21181 gttcgccaaa agattggcat ggtctttcaa agttatgaac tctttcccca tctggatgtc
    21241 ttacaaaacc tcatcctagg ccctatcaaa gctcaaggaa gggacaagaa agaagtaacg
    21301 gaagaagctt tgcaattact agatcgtgtc ggtttactgg ataaacaaca tagctttgct
    21361 ttgctttgcc cgtcaattat ctggtggaca gaagcaacgt gttgcaattg tccgtgccct
    21421 cctaatgcat ccagaaatca tcctttttga cgaggtgact gcttcgctgg atccagaaat
    21481 ggtgcgtgag gtgctggaac ttatcaatga tttggcccaa gaaggccgta ccatgatttt
    21541 agtaacccac gaaatgcagt ttgcccaagc cattgctgac cggattatct tcctcgacca
    21601 agggaaaatc gctgaagaag gaacagctca agccttcttt accaatccgc aaaccaaacg
    21661 agcccaggaa tttttaaacg tctttgactt tagccaattc ggctcatatc tataaaggag
    21721 attcttatga aactattcaa accactctta actgttttag cacttgcctt tgcccttatc
    21781 tttatcactg cttgtagctc aggtggaaac gctggttcat cctctggaaa aacaactgcc
    21841 aaagctcgca ctatcgatga aatcaaaaaa agcggtgaac tgcgaatcgc cgtgtttgga
    21901 gataaaaaac cgtttggcta cgttgacaat gatggttctt accaaggcta cgatattgaa
    21961 ctagggaacc aactagctca agaccttggt gtcaaggtta aatacatttc agtcgatgct
    22021 gccaaccgtg cggaatactt gatttcaaac aaggtagata ttactcttgc taactttaca
    22081 gtaactgacg aacgtaagaa acaagttgat tttgcccttc catatatgaa agtttctctg
    22141 ggtgtcgtat cacctaagac tggtctcatt acagacgtca aacaacttga aggtaaaacc
    22201 ttaattgtca caaaaggaac gactgctgag acttattttg aaaagaatca tccagaaatc
    22261 aaactccaaa aatacgacca atacagtgac tcttaccaag ctcttcttga cggacgtgga
    22321 gatgcctttt caactgacaa tacggaagtt ctagcttggg cgcttgaaaa taaaggattt
    22381 gaagtaggaa ttacttccct cggtgatccc gataccattg cggcagcagt tcaaaaaggc
    22441 aaccaagaat tgctagactt catcaataaa gatattgaaa aattaggcaa ggaaaacttc
    22501 ttccacaagg cctatgaaaa aacacttcac ctaacctacg gtgacgctgc taaagcagat
    22561 gacctggttg ttgaaggtgg aaaagttgat tagtcattaa ctcttaaaag gaactggatt
    22621 ttaagatcca atcccttttt aagattttac ctataacatc ctgagtctat ctaagatgtt
    22681 caatctgaac acagtgtaca tactttatct tctattgcat atactttatc acataagata
    22741 cgaatatcct cttcactatg actagcaatc aaaattgttg tccctttttc actagagagc
    22801 tttctaaaca atgttctcat attttctaca cttgatttat ccaaggcatt cataggttca
    22861 tctagtaaaa gaatagaggg attctccata attgcttgag caatccctag ctttttcctc
    22921 atacctagcg aataagtttt aactttctgg tctttttgct catatagacc aactattttc
    22981 agtgtatcat tgatttcctg attaccaact actcctcgta tgcttgccaa atattgtaaa
    23041 ttcttaaagc cactataata atttataaaa ccaggttctt caatcaaagc tcccaaatta
    23101 gctggaattt ttctctcagg aacaatattt tccccattga ttaacacttc tccataagac
    23161 ggactatata aaccagctat taatttaaac aatacacttt tccctgagcc attcgcacca
    23221 gtaattccta taatttcccc ctgtttacaa ctaaagttaa ggttttgaaa aacacatgtt
    23281 ttttttaatt ccaactgaat attttttaat gtaattattt cattcattct ataaacctcc
    23341 tcttttgacg agtgaaatag aaaatgcttt taaaaagaaa gactaaaaat agcaactgaa
    23401 gaaataaatc tcgtcctata tctccattcc ctcgatttaa aatataaaat agataattag
    23461 ttcgatttcc tacaaataga ccaccaaaca caatcatgag taaaaagaag ctaacacaag
    23521 aaaagttcat ttgctcattc gctcctagta cgtataacat aaagcaaaac aagactaaca
    23581 cacaagcatt caaagaatca actataaaca aaactcctat atcccagttt ggtaactgta
    23641 acataaattg aatcactaga acttttacca tgattaaaat gagtccataa agaaaacagg
    23701 tccaaatctg atacctaatc cagagcttaa tagaagaaaa tcgaatcact tccataaaga
    23761 aatcggatgc tcttctacga tatacaactg ctagaaaaaa tgtatgaata ataaaccaat
    23821 gaagcaacca tatagataag actaaaaaag agttttgact cagattaggc ccttttaaaa
    23881 tttctataac aagtctatca tttccttcta accaatacca taatcctaaa caaatcaata
    23941 tccaaaaaag aacataaccc caaaagtact tggtatagat tatctgattc aacctccaca
    24001 tgtgactact taactttccc atttccaact tttacactct cctccagttt ctatgaacag
    24061 aaaatacagt caatggaatt atgatagata gtaatgtaag ccaataaatc aatgcatacg
    24121 gattggaatt taccatatac tgaaaaattg gcaataatcc aattatccca ttgtccaact
    24181 gataaatcca gaataaggat tctacaaata aaaaagtaaa cagaaatact aagctcatgt
    24241 ttgatttttt aaaccaagaa aaactgctaa tagtaagtaa ggataaaaag aaatagtatg
    24301 ctatataaga gaaaaaaaat cctataaaaa aactagcatt gtttgcaata cttataccat
    24361 aaaattctct taaaaaatca acctccttta tctccaaaga gaagctaaaa ccattactaa
    24421 atgcaatcag aaaaatcaat aaaaataaag tcgccgtcca aatccccgta ctaagagctg
    24481 ctaatttgaa actaaaactg gtaaagtgct taattgattt cagacgaata cgacactcca
    24541 acctattaaa atagttattc atcaaataaa aaaagaataa tatatatgtg aacggaaagc
    24601 aatatactcc agtcgtcata tcttgaagta aaactaagat ccattctaat acatttggat
    24661 ggattgaata ttggcgacag cgcaataaat atactgtact agataaaaca caggatagca
    24721 gtaatataaa ataaaccaat actgctaaga aatctttttt ataaaattga acaaattgtt
    24781 tcattataca tagtcctctg aatgtagaaa aaatgtacca taaacaacca aacaactaac
    24841 aaataaaata aaagcaagat gcccactaac taaggaaaga ctgatatctt tctgatatcc
    24901 caaagctagc gttgtcacag gttctaagta agatagccct aaaatagccc ataaaatacc
    24961 accaaccatc atataggcaa ctgggatgaa aatagctcct aattttttct tcactagcaa
    25021 agcactagct agtccaaaaa tagagaacac agcgccccaa actccatacc agagagtcgt
    25081 cacaagacta tagagaaact gattggaatc aaataattct tttaaggcac cactataatc
    25141 tccaatataa atttcctgat aaggagtcac taaaagatta attcctaata ataataaata
    25201 ggggagaaaa aagactagaa aagaagaaat aattgcagta ctacctacaa tagctagata
    25261 cctcttttta gaaattcggc acaattgtgc tgttagaaaa tgactctcag catcctctat
    25321 tatctgacta gaatagggca gtgtacagat aagtgcagct actaggctaa tcggtgaaaa
    25381 tcctcgaata gaagaagcgg caaaaaaaat cgataaacct tcaattttat aaataccatt
    25441 gaaagcaagg aaatttccta aactcatgca aagaagggtc aaaaataaag acatataaaa
    25501 ccgaggtgat tgaacgactc gtacaagatt acaaatgaaa aattccatcc ttactcctcc
    25561 ttataataaa aatagggtgt agcattcttt tttcatgcta cacccacaat caaccatctt
    25621 taaggcttac tctgacaagt aagttaataa gaatctggac tccaagaacc tgaagtatga
    25681 attcttacat aatttccaaa ttgtggcgcc atagctaatc tagtaccaga accaatataa
    25741 ttgtcaccac ctccattata gtacatgaca atcctagagc cagaccccaa tgaatatacc
    25801 ggggtaatat ctgacccact ataggcgcta cgaatagagg tatttaacct tttaccgcca
    25861 ccagtgctgt cactattatt aattccagca gaggcgtttt ctttctcaag ctcactagtt
    25921 gtatccgaac cccaacgcgg caacgttaaa tcataatttc caatctgtct agctaaaact
    25981 gtagggagaa acaaactaga tgcaattgta actacgcaaa aaaggaatat atttttcttc
    26041 ttttcatgac atcgtcctct taagaagtga taaacaagat agttgattga tcaatttgat
    26101 acatattaca ttttcattat atcaataaaa gaaagcgttg tcaattattt tatttaaaat
    26161 attgtcatat tttaaataaa atggtaaaag agactcggta gcctcgtctc tctttatctt
    26221 actgacctaa ccttcttgcc aattttcttg gtcttcttta aagcgtttta gaagatcaag
    26281 gccctctggc gtgatgtaac cttcttcttg ggctagatgg ataagctcgc tatagtttga
    26341 aagcgtcaca agtttaacac cagcatctgc aaagttctta tctgcttttg gcaattggta
    26401 gctgaaaatc gctacaactc caagtacatc tgctccttct cgcttggctg ctgctacagc
    26461 ttcaagaact gaaccacccg ttgaaataag gtcttcaacc actaccattt tttgaccttg
    26521 agctacgcga ccttcgattt gattaccagc tccgtggtct tttggtttgc tacggatgta
    26581 ggcaaaaggc aagtccatct tatcagcaat aatggctccg tgtggaatcc ctgctgttgc
    26641 agttcctgca atcacttcta cttcaggaaa ggcttctttg atagcttcca caaaaccatt
    26701 ttcaattagg gtacgagttt ctggataggc tagtgtcaca cgattatcag tgtaaatcgg
    26761 tgacttgata ccagatgccc aagtgaaggg ttcctctggt ttgaggtaaa cggcttggat
    26821 tttcaagagg tggctagcga tatctttagc aagtgtcatg gtattctcct tttatttttc
    26881 taatctagtt ctttaattcc agtcctgtgt ccattcatcc ttgatggcat gataagctgc
    26941 aacaggatcc tcagcttggg taatgggacg tcccactacg atatagtcac tgccgatttg
    27001 ataggcatca gcaggtgtca tgactcgttt ttgatctcca actgcaacac cagctggacg
    27061 aatccctggt gtcagacaga taaaatctgg attggtagcc tgcttgatga cttgtacttc
    27121 ctgagccgag caaacaacac catccaagcc agcttcagct gtcttcttgg catagtgaat
    27181 cacagactct tgcagactgg tttggatatt ttgaaactcc tgcatctgag cttctgacgt
    27241 tgatgtgagc tgcgttacag cgatcaattt ggcttgactc ccaagacctt cacgcgccgc
    27301 cttcatcatc tctacaccac cagccgcatg gacattagtc atatcgacac caagctgaga
    27361 caagaccttc atggctgact tgactgtatt aggaatgtca tgaagtttga gatccaaaaa
    27421 gacactatga cccaaacctt ttaagtagga cacaatctca ggccccgctg cgtaataaag
    27481 ctccatccct accttgagat aaaggctttc ttctgctggg aaaagagcta aaaattcctt
    27541 gaccgcctca aaactaggaa aatcaagagc aatgattgga cgatgttctc gcataggttt
    27601 ctccttttac ctttactagt gagagagtct ggccaacaga agccacgaaa aaaggaacct
    27661 gccaacagca aggttccacg aaaaatgggt agtctccacc ctttcaccgt ctaaccttag
    27721 ctgcctctct ggactgcttt aaaggttttc tattattcta ttatttctac tagcacttgt
    27781 caagtaaaaa catggtcact aaagaactat aagagaaaag gtaaacctag cgacgcgatg
    27841 agcgctgggt cgtttgattt cgattgctct cttcctcttg ttttttctgt tcttcttcct
    27901 gttttttctc ggcttccttg gcctcttgtt tggctttttc ctcagcctcc ataattaatt
    27961 tatccgccac agtgtaactg taaattccag cttccatgtc gaccacactc ggttctgaca
    28021 attgtggctt aatcttactg taatatggca gtttcttact catttcagat agaggaacca
    28081 agacttcgtc cgaatcattc atggtcaatc gaattaaatc ggatgtcacc ttgcttgggg
    28141 ctaattccac cttttggata gccgccttga gttctgggct aatttgagca agttctgaga
    28201 caaaaacctt gatttgttca ctatcattaa agagaactga taaataagtt tctggtaaac
    28261 tgttcagact cacagaacta gtctcaagct gaccactgga aagaatagga taatgatttt
    28321 caccagaaat atagtaggcc acaatatcat attccttgac cttaatagtg aacttagttg
    28381 gaaattgata gacaagttga gctgattcaa cccaatagtt agacttaatc tgcttttcat
    28441 attttgcctt gtctagcaga aggttaatcg tataatccga atcctgaatg cctgaagcct
    28501 gtcgaatatc atcagctgta gtttgcaccg ttccctcaac acgaatatct ttcatggtcg
    28561 cataaggact gagcaagtag gcagagacaa tcaataaaag cagacttgga aataaaatcg
    28621 tgaaggctcg caagatatgg ataccaggaa tctttgcttt ggctggtttt tcctttgtag
    28681 cctttttaga aagcttttta tcctgttcct ccttctcttt agactctggt tcttctttct
    28741 cttctttctc tttgtcagcc tctgaggatg ctactttttc ttcagactct tccttagctg
    28801 attctgaatc ttcctggtct gtttcactct cctggtcctg tttgtcctct gacttctcag
    28861 attcttctcc cattcgagct tgtctttcct tttccttctc ctcagctaga gccgcctctt
    28921 cttcagcctt cttttttaga tattcttggt ttcgtttctg ccattctgat aactctttca
    28981 attcttcgag gatttctttg tcctcatttt tcttatcttt tgacatttac tttccttatg
    29041 ataaatcttt tttcaacaat tgataaaaat ctgctagaga tttcaattcc ttagaagcct
    29101 tcatcttagc ttggtaatct tccttgtgac ttagtaagtg agaaagcttc tcttccaaac
    29161 tatccaaggt caaatcgctt tcttgaaggt cttctgcata gccttttttt acaaagtaag
    29221 ctgcattttc aagctggtca ccacgactag cttcacgacc aagcggcaca atgacatgca
    29281 attttgctat cgccaagagc tcaaaaatcg tattggcacc acctcgtgtc acaacaatat
    29341 cagccaattc catcaagggt tgatagagat cggtcacata gtcaacacga aaaagatttt
    29401 ggctcaactc attcaggcta gaatctccag ttagattgat aatattgtag cgctctgtta
    29461 gttctttctt atggtctgtc accaattggt taaagacacg agcacctgca gaaccgccaa
    29521 caaacaatac agtcggcaat ttatgattaa agtggctttg aatatccacc aattcatctg
    29581 gttctggatt tttttgatct gaaaccttgg tcactgctcc cacatgctca accttagaca
    29641 aactcgaagc ttgctcaaag gttgaataca tcttagtcgc aaatttatag gcgattttat
    29701 tggccaagcc catagacagg tcagattcgt gaataaagac aggcactcct gacacacgcg
    29761 cagcgataac aggcggtact gagacaaagc ccccctttga aaaaagggtc tgtggacgaa
    29821 gtcgcaacat gataaagagc gattggacga ttccccagca aactttgaag acgtccagca
    29881 tattttgcca agagaaatag cgacgcaatt ttccagtcgc aatagaatgg aaggtgacat
    29941 ccaaacctga cttaaggatt tcttggtgtt cgataccacg cttgtccccg atatagtgga
    30001 cttcccaacc atcttcgatg aacttgggca ttaacaaaag attgagggta acgtgtccaa
    30061 ccgtcccccc acctgtaaag acaatttttt tcatattatt cttttaactc cgctactgtg
    30121 tcgataaaga ggtcgccacg tacttcaaag ttagcataca tatcccagct ggcattggca
    30181 ggactaagaa gaaccacatc tccttgagtc gcaagctcat aggccttgcg ggtcgcatct
    30241 gcaatatctg tcgcctccac ataagcgaca ccagccttgt ctgctgcccg tttgacacgt
    30301 tctgcagatt gacccaggat gaccatcttc ttgagtccag taatgtctgg caccaattcg
    30361 tcaaactcat tgccacggtc caaaccacct gcaatcaaga cgaccttgct gttatcaaat
    30421 cctgacaagg ctttttgagt agccaagata ttagttgatt tactgtcgtt atagaattta
    30481 acacccttga tgtcatccac aaactggaga cggtgtttga caccaccgaa ggctgaaaga
    30541 gtttccttga tggtttgatt gtccacacca cgaagcttgg ctacagcaat agtcgcaagg
    30601 gcattttcca cattgtggct acctggaaca ccgatttcat tcgctgccat gactacttca
    30661 ccacggaagt agagttgacc atcttccaga taagctccat caaccttttc aagtgttgaa
    30721 aatggtacaa cagtggcttc tgtcttggaa gtcaagtctt ttgccaagtc ttgattaaag
    30781 ttcaagacaa ggaaatcagc tgctgtcatc ttgttctgga tattccactt ggctgctaca
    30841 tattccgaaa atgacccatg gtagtcgata tgagttggca tgaggttggt aataaccgca
    30901 atctctggat ggaattcttg aacacccatg agttggaaag aagaaagttc cataacaagc
    30961 gtgtccttat ctgatgctat ttgagcaacc tgactagctg gatagccgat attccctgat
    31021 aaaagaccat gttgcccagc agcagtcaaa acttccccaa tcatagtcgt tgtggttgtc
    31081 ttaccgttcg atcctgtgat accaataatc ggtgcttctg aaatcaaata agccaattcc
    31141 acctcagtca agactggaat tcccttggcc aaagcctttt caatcatggg attgttgtag
    31201 gggatacctg gatttttcac cataagggca aactcttcat ccaagagttc caaaggatgg
    31261 ccacctgtaa tgaccttgat cccttcttcc agcaaacttt gggcagctgg attgtcctcg
    31321 aaaggtttcc catcatttac tgtcacaatg gcacctagct tgtccaacaa acgagctgca
    31381 gattcaccag acttggccaa acctaaaaca aggactttct tatttttaaa ttgatctatt
    31441 actttcatgt ctcgaactcc atttctactc ctactatttt accattttta tggaaataaa
    31501 aaagccacaa agtgtgtttg tgactctttc ttctaactga atcttaccat atcatctatg
    31561 tgataaatcg gtaactcgaa tgacctgatc cacttgttcc caaatcagag gattgtgggt
    31621 cgcaataata atggtccgat tcggattttt taaagattct aggatggaaa gtaattcctc
    31681 agagtttttg gggtctaagg aagtggttgg ttcatctgcg aggatcaaag gtggatcctt
    31741 taaaattatc ttcgctaatg caacacgttg tgcttctcct cctgataact caaatatagg
    31801 ttgcttcaaa tccaaataag agaggtttac acagtttaga gcttgtttca tcaaagagat
    31861 tttctctttt tccttcaact ttttaccaac taaacccaga ttgagattct ctttgacggt
    31921 ttggctttca attaagccaa aatcttgaaa taagtatccc aagtaatctc taaagaaaac
    31981 agaaggcttg atgtccttaa gagaagtacc atcatagatg atttgtcctt tgtcatatgg
    32041 ctctaatcgt ccaatcatat tcaagaatgt tgtcttacca cagccacttg taccgattaa
    32101 ggcataaatt ttcccacctt caaaatgaag atttgtatct gaaaatagct gacggcttcc
    32161 aaatttttta gatatattct ttagttcaat catcctattt tcctttcata attgtcatag
    32221 aaacacgaga ttctttctgc gcttgacggt aaagcgtcag aactgcacta gctagaaaga
    32281 ctaataaagt gagcaagcca atcaccaagt ctcgactgct taaaataaag agactagcac
    32341 caaatacaaa actggcaaat tgactaacca tatactgagc atgtgtttca aaaaatcgta
    32401 aacctgaaat tcgtttaatc aaaatatctc ggcggaattg ctcgaaatat agaagattga
    32461 cagaataaaa tagtaacaag gaactagcta tccccacaat agctcctaag attaaagttg
    32521 ctgtttcagt ttgaacttca ttataacgag ttagataaac acttcttcct tctttaagat
    32581 aggatacttg ctcataaatt ccagctttct tcaagagttc tagcccactc tcatatcctt
    32641 tgataaagag ttgttttcca gcattgatag accaactaga taaggatata aaactatcac
    32701 ctgtagaagt cggcgtgaat accactaaaa tcggatcagt caaatactga gtagatacgg
    32761 gattctcacc gttattataa acaaaccgct tttctcccat tgaaagataa ctaacgtgcg
    32821 ctttcatctc ataatccaaa ggagcacttg cctcctcacc agattttcca taataactca
    32881 atctttcttc aaaaactttc ttaagttctg cttctcgaga gcgcaaatgt tctgggagca
    32941 agaggataaa ctcacctttt tggagatggg ctaacttctg tttggtctca gcatctacca
    33001 cgaccttttc cttgtccaaa taactgggac taacatagag cgtattagca tctggactat
    33061 aggtatccag tgtctctccc tgttcatttt ttccttgtgg attggcaaaa tggagcagat
    33121 tatcctttac ataaagagct tgttcttctt cgattgcttc cttggcaaag gcataccact
    33181 tgctctgatt ttctgtatct tttcctctat cacctaagcc aaaagaaatt tgataatagt
    33241 ctgctctatc ctgccatgct tgttttgaaa tttcaagttc tttcaatcgt tggtaagaca
    33301 tcaaacctgt cttaacagcg tagcctactg taaagacagc aaccaactga cacaataggg
    33361 ttaaaatcat caggcgttta aggggtaatc tccccttaat aacgggaact aatgctttgt
    33421 aactcaaact cattagataa agaagcatta gtaaaattga aatcgccaat aaaaacaaca
    33481 gatagaaact aatcccaaaa ccataggtgg ctaacaagat aggataaaac aaaccttgac
    33541 taaaaagaac gactccccca cctaggaagg aaaggagggc tgatagaagg agccatttga
    33601 tatcagtaga taaagaatgc cccatgatgg ataagagagt ctgaccagaa aagagtttta
    33661 tacctgctgc tctcatttcc ttaatccgag tgataatcac taaagcaaag aaagataagc
    33721 caaatattgc taaactaatt aaaataaggg gatttagtaa tattcgaaaa gcaagaaaat
    33781 agggcggtat ctttcggtca gcacttgctt tataacccaa atctcctaat ttatcggcaa
    33841 gcttttcttt cgtcaaggag cctgacaaaa ggagataact atttagcgga tcactacgtt
    33901 cacgactttc ttggctagct tcttggaatt cttttggtaa agttccctga ccataagttg
    33961 cataagtaaa gtgagtcgtc ccatccttac tcggctctac aattcttcta gctattaaac
    34021 tctgttctga gtttgcaaaa ttctccaatt cctgttcaaa tacctcacgc gtcggttcct
    34081 gagtatcttt tttgacacga agtaaagaaa cggaatcata gcttgcatat aaatattgtg
    34141 gcgcacgtaa gacaataatc caagcaagga agaagctgag aaaaaagttg ataataatat
    34201 gaatagtttc ttcatagtag actccttgta aacaaaattc cccctgtaat ttcttacaag
    34261 gggaacgatt taaatcaatg aacgattagt cataatcaca gtaaaatgct acttgttctc
    34321 cccatttagt ccaaatccat gcataggagg tttttccagc agaagcttct cctttatctg
    34381 aatgactatt ccatctactt acaagagaag aataatgata ttttttacca tgatagtaat
    34441 ttgaaaaagc ccaaccacct cctgaacctt ctccatacgt ccatactcct ccatctggat
    34501 attgtacagc agctgatgca gctcccaata atgtaaaact tgaaataaga gctagagcaa
    34561 gtaatctatg ttttttcgtt ttcattttat tttttctttc aaaaaaagca caccttgagc
    34621 aacaatgcaa caaaataaac cctcctctct cttttgttga aaccgctttc ttatgtgata
    34681 aaaatatcat ttttattatt tgttgtcaag gaaaaaatcg aattttttag atattttact
    34741 acattgcctc tatgaataat attatatagt agttttattt taaaataata tgcaaccagt
    34801 actaaccaaa tataaaatag atgccattaa cgaattttat tcaagttttt cccattcata
    34861 ctatccaagc aaaagagatg atgttatagt acaaaacaat tcaaactatt gtaaaattcc
    34921 tagcaaaaaa gagagccaaa actctctttt ttatcttctt ttactttttt tgactggcat
    34981 gagtgtaatg tctctaacac taaagtaagc taggatcaac atggctattg ctaggaatat
    35041 ttctgttggt aattgaaaaa ttttcagaaa agatagaacc aataaaatca agagtgccac
    35101 taaaatacat accatagcga cgatattgac tgtcccttta atgctttctg gtgtcgcaaa
    35161 tacatagagt aggagcagta aaattcctag gactaaatag accatctttc tctctttcta
    35221 gctcttattc agctgatttt ttcttcttgt tagctttctc acgctctgct ttgttaagga
    35281 tttgtttacg caaacggata gactcaggcg ttacttccat gtactcatcg tcgttcaaga
    35341 actcaagaga ctcttcaagt gtcaagatac gaggcgtctt gataacagct gtttggtcct
    35401 tagtagctga acgaacgttg gtcatttgtt ttgccttcgt gatgttaact gtcaagtcat
    35461 tttcacgaga gttttcaccg atgatcattc cttcataaac ctcagtacct gggttgacaa
    35521 agatcgtacc acgttcttcg atagacatga ttgagtaagt tgtagcctta ccagcatcga
    35581 tagaaacaag ggcaccacgg tgacgtccac caatttcccc tggaatcaat ggcaagtatt
    35641 ggtcgaaggt atggttcatg ataccgtaac cacgagtcat tgacaagaac tcagttgagt
    35701 atccaatcaa accacgcgct ggaacaagga agaccaaacg agtttgacca ttaccagttg
    35761 aaatcatatc caacatttca cctttacgtt cagaaaggct ttggataaca gacccttggt
    35821 attcttctgg agtgtcgatt tgtacacgtt caaatggttc acatttaaca ccgtcgattt
    35881 cttttacgat aacttctgga cgagatactt gaagttcata gccctcacga cgcattgttt
    35941 cgataaggat tgacaagtgc aattctccac gtcctgaaac agtccattta tctggtgaat
    36001 cagttgggtc aacacgaagg gaaacgtctg tttgcaattc tgcctgcaag cgttcttcca
    36061 ccttacgaga agttacccat ttaccttctt taccagcaaa tggtgagttg ttgaccaaga
    36121 aagtcatttg aagagttggc tcatcgatgt gtaggattgg aagagcttct actgcatctg
    36181 tcggagtgat ggtttcaccg acaaagatgt cttccatacc tgaaacggca atcaagtcac
    36241 ccgctttggc ttcttggatt tcacgacgtt ccaaaccaaa gaaaccgaag agttttgtaa
    36301 cacggaagtt tttagttgta ccgtcaagtt tagaaagggt aacttggtcc ccaaccttaa
    36361 ctgtaccacg gaagacacga ccgataccga tacgtccaac gaagtcattg tagtccaaaa
    36421 gtgacacttg gaactgcaaa ggctcatctg agttatctac tggagctggg atatggtcga
    36481 taatcgtgtc aaagattggt gccatagtcg cttcttggtc agctggatca tctgacaatg
    36541 aagaagttcc gttgatcgct gaagcataaa ccactgggaa atcaagctgg tcgtcatctg
    36601 caccaagctc gatgaaaagt tccaagactt catccactac ttctgctgga cgagctgatg
    36661 gcttatcgat tttgttaaca accacgattg ggacaaggtc ttgttccaag gcttttttca
    36721 atacgaaacg agtttgtggc atggttcctt cataggcatc tacgaccaag acaacaccgt
    36781 caaccatttt catgatacgc tcaacttctc caccaaagtc cgcgtgtcct ggtgtgtcca
    36841 taatgttgat acgagttccg ttgtaagcaa cggcagtgtt tttagcaagg atggtaatcc
    36901 cacgctcttt ttcgatatcg tttgagtcca tagcacgctc tgccaattca gtacgtgcat
    36961 caagcgtttc tgattgtttc aataattcgt caaccagggt tgttttaccg tggtcaacgt
    37021 gggcgataat cgcaatgtta cggatatctt ctcttaattt tgtcatgatt tcctctataa
    37081 tattcaaaat ttattttcta actgaacgat tataccataa tttcaaataa ataacataac
    37141 tcaagcaagt gtaaatgttt tcactccgct tttcttttca cgtcaagcct tttcaaagca
    37201 agcgacttat gataagatag gcacagtatg cgtttagata atttattagc ccaagaaaaa
    37261 gttagccgaa aggccatgaa gcaagcactc ctcagagggg aaattctagt cgatggttgc
    37321 ccagcccgct ccctagctca aaatatcgat acaggactac aagaactcct ttttcaggat
    37381 cgaatcattc aaggctatga acacacctat cttatgcttc ataaacctgc tggtgtcgtt
    37441 acagccaaca aagacaagga acttccgacc gtcatggact tgcttccatc tgacatccag
    37501 tctgacaagc tctatgccgt cggccgactg gaccgagata caacaggact ccttctcttg
    37561 accgataacg gtcccttggg cttccaactc ctccatcccc aatatcatgt cgataagact
    37621 tatcaagttg aggttaatgg acttctaaca cctgaccata tccaaacctt tcaaaaagga
    37681 attgtctttt tagatggcac tatctgtaaa cctgcaagac tagagattct atcagcaagt
    37741 ccttccctca gtcaagcctc tatcaccatt tcagaaggaa aatttcatca aatcaagaaa
    37801 atgttcctct cggttggtgt taaggtgact aacctcaaga gaatccaatt tggggacttc
    37861 acattgaacc cagatttagc agaaggtaac taccaccctt tgaaccaaaa agagttacaa
    37921 atcattaaaa actatttaga gatgagtcga taaaacaaaa aaagctttaa aactaaagct
    37981 tttttctttt atttaccgaa aaattaaggc gattgctaca atccagttaa ctacagaaat
    38041 cacaattcct aagatattaa gaatcttttc tattttatag tctaattgtg actctttttg
    38101 gtatgaaata gccaagacca atcctatgat acccaaaatc aggcctacaa ttggaaataa
    38161 caaaccaaga ataatcgaca agatacccac aaaaagtgga tttttcttct tttctttcat
    38221 gttctaagaa ctctttaaat tttatacaaa ttaattatac tataaaacaa tagcttcatt
    38281 ctatcattcg actaatttgg aaataaggtt agctagtctt cactttccct ttccaagaat
    38341 ccaagccata agaaaggata taaatctcag aaaaaccttg ttttttcaag taaagagctg
    38401 catttgtaac tcgttgcgca cgttggtttt cgtagagaag gacaggttta tctttacgaa
    38461 gggctgcaag actagttttc aactgacttg aaggaatatt gcgtgcacca aggatatgtt
    38521 ttctgtggaa ttctgctggg tcgcgcaaat caatcaattg acccgtacga atcaaggctt
    38581 caaactcctc attgtccaca attttagccg cacggcgaat acgaagatag ttaaagccca
    38641 tccacgccaa cattgctagt ataagtgccc acaaaatcca agtaaccatt agttcttttc
    38701 tccatttttc tcaatataat ccaattctac cttgtgctct ctgcgaagaa ctgcttctgc
    38761 ctctagatag tctaatttat ccatcaaccc tgcatcgtaa atccgagata gttccaactt
    38821 catcagttca atatcatata agcgttttcc catgtaaaca ataataccaa atcgtttgag
    38881 gaattgctgc acatcataga atgttttcat aagactcatt ctagcaaaat tttgtgtttt
    38941 tttcaagaag agactcacac aatgctcctt attttcctat cttctttagc gattctaagg
    39001 caagtatggt acaataaaaa catgagaatt caacaattac attatattat caaaatcgtc
    39061 gaaactggct ccatgaatga ggcagccaag caactcttta tcactcagcc aagtctctcc
    39121 aatgcagtgc gagatttgga aaatgaaatg ggcattgaga tctttatccg caatcccaag
    39181 ggaatcacct tgacccgtga tgggatggag tttctctctt atgcccgtca ggttgtcgag
    39241 cagacccagc ttctggagga acgctataaa aatcctgtcg cccaccgcga actctttagc
    39301 gtttcgtctc aacactatgc ctttgtggtc aatgcctttg tctctttgct caagaaaagc
    39361 gatatggaga aatacgaact cttccttcgt gaaactcgga cttgggagat tatcgacgac
    39421 gtcaagaact tccgcagtga ggtcggggtc ctcttcttaa acagttacaa ccgtgatgtt
    39481 ttaaccaaga tgctggatga caatcacctg ctagcccacc atctcttcac agcgcaaccg
    39541 catatctttg tcagcaagac caaccctctg gcaaagaaag acaaggtgaa actgtctgat
    39601 ttggagaatt tcccttacct cagctatgac caagggacgc acaactcctt ctacttttca
    39661 gaagagattc tttctcagga acaccacaag aaatccattg tggtcagtga ccgtgccacc
    39721 ctctttaatc tcttgattgg tttggatggt tataccattg cgacagggat tttgaacagc
    39781 aacctaaacg gagacaatat cgtttctatc ccactggata ttgatgaccc gattgagctg
    39841 gtctatatcc agcatgagaa aaccagccta tctaagatgg gcgaacgctt tatcgactat
    39901 ctactagaag aagttcagtt tgatagttga gaaatgataa gaaccaatat gtaggctagc
    39961 aacaacctgc acattggttc tttttactta taattaaaag tttcccctgc caacttatca
    40021 gctagcttgg gaaagagagt ataaaactta tgggctaggt tcaacaaaat cgggagattg
    40081 agttctcgtt tatttttgcc tataatcttg acaatctttt tagccactgc atctgcctct
    40141 aagaggaagc ggtcaaccga tttaagataa gttccatctg ggtcagcttg gtcaaaaaat
    40201 cctgttcgga ttggacctgg attgactgtt gtcacataga ctccataggg cataagttcg
    40261 agtcgcagag catttgaaaa accaatagcc gcaaacttgg tcgctgagta aagactagac
    40321 ttgccagtag ctattagacc tgccatgctg acgatgttga tgatatgccc tttgctgctt
    40381 tccttcatac gagccgcaag gtgacgagac agattcatca gggcaaaggt attgacctca
    40441 aacatctggt gaatatcttt atcagcaatc tggtcaaatc cctcaaaaat cccgtaacca
    40501 gcgttgttaa tcaagacatc aatcttgcca tagcggagat aaagatcagt taccagagct
    40561 tctagggctg aatcgtcggt aatatcaatt tcaatcaatt ctgcatggga ataatttccg
    40621 tagagttggg ctaatttttc cttatttcta ccaagcaaga tgagttggtc attgggcagg
    40681 agtttgacca tttcttgagc tagaccaccg ctagctccgg taatgagaat agtaggcata
    40741 cttatccttt ctgtgactgc tagatttcca cttcttccaa gtctttgacc acatggacat
    40801 tttcaaaaat tgtggcagcg tccttcttga gtttgcttat atcttttgag aggaaacggg
    40861 cactgatatg gttgagtagg aggcgtttgg cacctgcttc taccgctact tgtgcagctt
    40921 gcatattagt tgagtgacca tggttacgag caattttttc atcacccttg ccataagtgg
    40981 actcatgaac taggacatct gcattgacag ccagacgcac actggcatcc gtttttcgag
    41041 tgtctcctaa aatagtgata atcttacctg gacgtggcgc tgagatatag tctgctgcct
    41101 tgatttcagt tccgtcttcc aaaacaagat cctggccgtt tttgatttta ccaaaaagcg
    41161 ggccgaacgg aacaccagca gccttgagtt tttcagcatc cagcgtccct tctagatcct
    41221 tttgcatgac acgatagcca acacagaaaa tagtgtggtc cagctcctct gcatacacag
    41281 tgaatttatc ggtttcaaga attttaccca gagaatcttg gtcaaactca tggaaatgaa
    41341 tgcggtaggg cagacgagaa cctgacacac gaaggctggt taagacaaat gacttgattc
    41401 cttgaggtcc gtagatttcc aaatctgtct gctcttcatt ggcctgaaag gcacggctag
    41461 aaaggaaacc tggcaaacca aaaatgtggt ctccatgcag atgggtaata aagattttgc
    41521 tgaccttacg tggtcgaatt gtggtttcca gaatgcgatt ttgcgtacct tctccacagt
    41581 caaagagcca aacttcgtta atctcgtcca aaagtttcag ggcgagactt gaaacgttgc
    41641 gggctttaga gggctgacca gcccccgttc ctaaaaattg aatatccatt cgatactttc
    41701 taattaatca atatataaca tggctgtgcg gttttccgat cggaaatagc gtttgccaga
    41761 aaaagcagca gcttcttgca ataaatcctc ttggctgtag cctttgagac gttttcgacc
    41821 atcagccaat ctttccaaat cagtcaaagc tgtgagactt tctaggctga caacttcctc
    41881 gtccttgaca ggtttcatgt aaatcttacc agactcttca aagactaatt gatgggagaa
    41941 aatttgcgca atttcaaaga gcaagtcatc cgagattttc tcctcatttt cagagaaaat
    42001 ccgaccaagg ccgtcactct cataacaaaa accaaaggat ttaccagaca gattaagccg
    42061 aataaaaggc ttattttcta gggtgaaact tggctcagta ttgtaaagat tcagttcctg
    42121 actgagttct gcaaaataat ccgtcgcagc ctgaggactt tttttctgat agagttctgc
    42181 aaagtaggca ttaacaacac ttggcggagg tgtaataagt gttaactgct cctgctctgt
    42241 tttaccagct agaagctgat ccagatagac cttgtccaga cttgtataac ctccatactt
    42301 tagagccaaa gttttaatat cagtcataaa attcttctaa cctccattta tttttctcgg
    42361 aaatgtagcc tgtaatcact tcgccgtctt cctgataatc acgttcttcc agaattgcaa
    42421 cactctctaa atcatgaatc ttgtaggact ttgaaaaagg cactcgcagg gtaaatgctt
    42481 caaaaatttc cttaatctta tctagcaata atgcttgcaa gttttcacga ctgtcctcag
    42541 acttggcaga aatgagggta tatggcgttt gggtaggcgt gaaatcctcc accaaatccg
    42601 ctttattata aagcgtcaag tgaggaatat cttccatgtc caggtctttc atgatggaga
    42661 gaaccgtttt ttcatgctcc tcgtggtaag gattgctagc atcgataaca tgaaccagaa
    42721 ggtccacatg cttgctttct tccaaggttg acttgaaact ggacaccaac tctgtcggca
    42781 aatcttggat aaagccaacg gtatctgtca aagttacttg gagattgcct cccagatgaa
    42841 tactcttggt tgtcgcatcc agagtcgcaa agagctcatc tgcttcatac tgggtcttac
    42901 tggtcaagat gttcatgata gttgatttcc cagcattagt ataaccaatc aaaccaatct
    42961 taaaagtgct agactccaaa cgtttttctc tgacagtcgc acgatttttc tcaaccacct
    43021 tgagctggcg ctcgatatcc gtgatttgat tgcgaacgct acgacggttc agctccagtt
    43081 ggctttcacc aggaccacgg gaaccaattc cccctgcctg acggctgagc ataatcccct
    43141 gaccaaccaa gcgaggcaag aggtatttga gttgggctag gtggacttgg agcttccctt
    43201 catggcttcg agcccgcatg gcaaagatat ccaaaatcaa ctgcatacgg tcaatgacct
    43261 taacaccgag aacttcctct agattgacat tctgccttgg ggtcagacgg ttgttgacga
    43321 tgacagtagt gatttcttct gcatccacca taagcgcaat ctcttccaac ttaccagagc
    43381 cgacgaaggt cttggaatca tatttttcac gtttttgtct gtagctatct acaacgactg
    43441 cccctgccgt tttcgctaaa ctagccaatt cttccatgga gaggtcaaaa ctgtccatac
    43501 cctgcaattc cacaccaatc agcaggactc gctcctcttt tttctccgtt tcaatcatct
    43561 aaaaactcct ctatctggct taaaatgcgg tcttgtacac cagattctcc aatctgataa
    43621 aaggtgacct gcatgcgatt acggaaccag gtcagctgac gcttggcaaa acgacgggtc
    43681 gcctgtttaa gactctcacg agcttcctca aaggtctgct ctccacggaa ataaggaaag
    43741 agttccttat agccaattcc tttagcagcc tgtacattag gggaatggtc aaacagccac
    43801 ttggcctcat ccaaaagccc agcctcaaac atcaaatcca ctcggtggtt gatacgctca
    43861 taaagttgac tacgttcatc atccaagcag ataatcagcg gttcatacaa aatctcttga
    43921 ttttccaaat cctgaccaaa atgggcaatt tctaaggcac gcatagcacg acgacgatta
    43981 aactggggaa tctcaaggcc tgcttgctcc accaaatggg ctaattcctc atctgaatat
    44041 ggctccaaac tagctcgata agctaaaatc tcctcatgag gagtctcccc acctaggtgg
    44101 taaccttcta gcaagctctg gatataaagt ccagtcccac cggcgataat ggctagcttg
    44161 ccacggctgt gaatatcctc aatagtcatc ttagcttctg aaacaaaatc aaaagccgag
    44221 taagactcgg ttatctctct aacatcgatt aaatgatgag gaacagctgc ctgctcttct
    44281 ggactagcct tggccgtccc aatatcaagt cctcgataga cttgttggct atctccacta
    44341 accacttcgc cattaaagca ctttgcaact tcaatagcta gagccgtctt tccaacagca
    44401 gtcggtccaa caatcacaat tatttttgtt ttcatctttt ttccttgaaa aattcccatt
    44461 ttttcgttac tattattata acacaaaaag gtcagtcaga aaaatgtgac ctcttgagga
    44521 ggctggctga ttgagaatat aaaggaggaa gactcatggc taaaggattc gctaaaggtc
    44581 ttgtaacagg tgtcgcagga actgtcgctg ccgttgcagg tgcagtatac gcatttaaaa
    44641 agaaagtaat cgaaccagaa gagcaaaaag cagctttcat cgaagaaaac cgtaaaaaag
    44701 cagctcgtcg ccgcgtatca cgttaagaaa caaaagaagt tgggattatt ctcaacttct
    44761 tttttctatt cttttaaata gctaggtcaa acttcaactg tggcttaaca gggtcataat
    44821 ccaccaactc aaaatcttct gctttgatat caaagaaatt agtcccatca ggaacattta
    44881 aaaccaagcg tggttggcag tttgacggct cccgacggag caattcctga gcttgttcaa
    44941 attgattatc atagatatgg aggttgttga tgaagtagaa gaacttccca accttccagc
    45001 caaaatgttt ggcaatcatc atctgcaaag ccacatactg catagcgttg atgtggtggg
    45061 ccaccagcat atcattggag cgctgggtca aggtcgcatc cagatagatt tccccatcaa
    45121 cacgccggac atcaaacatg gtctgaaagg cgcacgggag cagcccatct gtttcttcga
    45181 aagcttggta atcccagagc gaaataatat tgcggcggtt ccaaggattg gtttccaact
    45241 gtttgagaag cttattgata atgtcgtgtt tcttaacaac ggcaccatag cgctcaccaa
    45301 tggttcccgt gtctccaact tcccagtcat tccagtagtg aacattgtac ttgtcattaa
    45361 gcacttctaa gctatttgac tggtcttggt aaatccagag aacttctttg atggcggatt
    45421 tgattgcaat gggacgcaag gttgtgatag gaaattctcc tttagataag tcgtactcgg
    45481 aaaaggcacc agttacatac ttggaattag caacagtccc atccttgtac ttaggacgag
    45541 cctgctctga gaaaacacct tcctttagaa tgcgttcaat attctcttta aaaatcgtat
    45601 ctgcttttgt catttcgttt cacctcattc attgtcctaa ctagtatagc ataaaaaata
    45661 aaagaggaac attactaact ctaggttagc attttcctct ctcattatct tattgcaata
    45721 caagtgatgc tgctccgata actccagcgt catttcctag agttgcaaga gctaatttag
    45781 tagatgtgcg tacttgtggg aaactatttt catcgtaaac tttttgaaca ccttgtagaa
    45841 ggaattctcc cgcagctgac acaccaccac cgatgacgat tgttgatggg tttaggattg
    45901 aaccaatgtt agcacaagcg attcccaagt aacgtgagaa gttacggtaa acaatcaaag
    45961 caaggtcgtc tccttctttt gcgagatcaa agacagtctt agcagttact tcttctccgt
    46021 tatcaatcaa gcgtttcaag gctgcatcgc cttcgtattc atcggcatag cgacgagtca
    46081 agttgacaat ccctgttgct gaagcaactg tctcaaggca gcctttttta ccacaagtac
    46141 atgagattgg ttggtcaaag tcaacagtga tatgaccaag ttcacctgct gcaccagcaa
    46201 caccatgaag caatttgcct tctgcgacaa taccaccacc aacaccagta ccgagtgtca
    46261 taaagacaac gtctggttgg ttatctccag cacccatcca gcgctcacca agagctgcta
    46321 cgttggcatc attatcgatg aaaaatggaa tgcccaaagc tttttcaatc ttttgtttga
    46381 ttggttgaag ggttttccag ttcaagttgt aggcaccgat aacagtccct ttttcacggt
    46441 caaccacacc tggtgatccc attccaatac cttggaagtc cgctgctgcc aatccaagca
    46501 agtccaaacg atgttgaata gactcaatca tatcatcaac gatatgactt ccctcatcca
    46561 aaatgttggt cttgattgac cattttcctt ggatttctcc tgctgttgtt aagattgcaa
    46621 atttgataga agttccacca aggtcaatcc caataatctt ttgactcatc atattctcct
    46681 ttttcattgt gtagtaattg aaaatgctta cagtactagt atatcaaaat ccattcactt
    46741 atgcaaaggt ttgcgtaaat gaattataag gaattttttc gcctaccagt atctgttaac
    46801 catctaaatg atcaatggca tattgagctg catcatttga aaatttatca aaatcagaag
    46861 ttaattgtct atacatacgt ttttttgaca tgtggaataa cgaattataa ctttttgcct
    46921 ttcctaaagc agcagaatat tcactattgc tatcattact agaagaagct gtacttgctt
    46981 gaccttcctt ccaaactccg tcagcgccaa cataataacg tccaccatca acccattcat
    47041 tgacagccat tttaccatcc gattttagat agtaatttcc ttgccatgta ctgtaagcat
    47101 aagaaccatc tgatgtcaaa taataccaag cttgataggt ggcatcataa acccattcac
    47161 ctttagccat tttaccatct gatttcaaat agtagtttcc ttgccatgca ttgcgagcat
    47221 atgaaccatc tgatttcaag taataccatg cttggtaaga agaatcataa acccactcac
    47281 cttgtgccat tttaccgttt gatttaaggt aataagctcc ttgccatgta ctgtaagcat
    47341 aagaaccatc tgatgtcaaa taataccaag cttgataaga agagtcataa atccattcac
    47401 tctgtgccat tttaccatca gctttcaggt aatagtttcc ctgccatgca ttttcactag
    47461 atttccattt ccatcaaaat agtaccaaga accgtcctgc ttaacccaac cacttgctgt
    47521 ggatgaagtt gtatcagttt gagttgtagc cgcttgtttt gctttaaaag cacccttagg
    47581 agcatttttc aattcgcaag ccacaccatc atgatcgcgg tctaacttgg cagaataacc
    47641 aggttctccc tcatgaagat ccgaatatcc attagcccaa gcttccttac aactcgaaaa
    47701 atgaatgttt tcctctgcta acacaggttg tgaaaacaag gctaaaattg gcaacgtcac
    47761 cagactcatt tttaaaaata gacgtttatt catttctttc tcccataatt atgatatcga
    47821 tttcaatatt attttatcaa acttatttca gcaattcaag gaaacttctg gtcttttcta
    47881 caaactcctt tggttttgcc ttattcaaga catgagggcc atctgggata atctgaaatt
    47941 gggattctga tattagttta tgaagacttc tcatagaact aagattcggt ttatctttga
    48001 taccacaaat tagtaaggtt ggataagggc aagttcctgc tatatccgtt aaatcaagtg
    48061 tcttcaactc ctcagaaact ccgaccataa gagccttgtc tgctccctgt ttttcaaata
    48121 ctcttttggg aagtagttta aaaatcagca actgaagata aaataggata ttccctgcta
    48181 atttaagcgg gcatcctgac agaatcaaag ctcgaagatt tggtaaatcg taactggaaa
    48241 gttctagtgc cagggcagca cctaaggaca atccaatcaa aacaaaaggt tctgtctctt
    48301 gagctaggtg ctgataaact cgctccttag cttgttgata gttactaact ccagaaggaa
    48361 ataactcgat agcctcagaa ggataatctg tcagtagatt ccgaacttct ttccaagact
    48421 ctgctgactg ccctaaccca tgcaaaaata tcagtttcat ctagttctcc tcaaggctta
    48481 gttcatacaa gcctctcact gcattacagc cgtaaatagc ttctgcttgg gctaaatctg
    48541 ccaaggtcaa gactttctct tctacctgtc ctgtttctag caaatactga cggtaaattc
    48601 ctggcaagat tccaagtcgg ataggcggtg tgtagagttt tccagcgatt ttcagaacca
    48661 aatttcctat agaggtttca agcagttttc ctgacttatt gtggtaaatc ttctcttgtt
    48721 ctcctaggct caaatgcggt cggtgagtgg ttttaaagta ggtaaaggat tgattcaaag
    48781 cagcttcctg aaggcagact tgggcctgac aaaagcttgt actgagaggg gttaatactt
    48841 gacgattgac ttctatctct ccagatttgc taaggctgat tcgcaagcgg taatcttgat
    48901 tagcttcaca atcctgacac tcttcctcaa tcttgtgtcc caagtcttct gcatcaaaag
    48961 gaaaggcaaa ataacgacta gcttttctca gtctttccag atgttgatct tcaaacagca
    49021 ggttcttctg gctgatttcc cctgtcgtaa tcagttggaa gcgggcttgt ttacgataaa
    49081 gaactgctgc cttttgatga acctctcggt attcagattc ccatgtgcta tcccaagtaa
    49141 tccctccgcc aactccataa atggcttgac ctttgtgaag ttgaatggta cgaatggcca
    49201 cattaaaaat ccgtcgtcca tttggaagca agagaccaat cgttccacag tagactccac
    49261 gcggttgagg ctccaagtcc ttgataatct ccattgtcgc aattttcggt gcacccgtta
    49321 tggaaccaca aggaaagagt gagcggaaga tttcaacaag gtccacatcc tctcgcaact
    49381 gactcttgat ggtcgaagtc atctgccaaa cagttgaata ctgctctacc tggcacagac
    49441 gctccacgtg ctcgctccca acttcagaaa tacggttcat atcattgcgc aagaggtcca
    49501 caatcatcat attttcagag cgatttttgg gatcctgttc caaccaactg gcctgttcaa
    49561 gatcttcttg gtcagttacc ccacgctgag tcgtcccctt cattggtcgt gttgtcaact
    49621 cgcgatcatt ttgctcaaaa aagagctctg ggctcatgga aatcactgcc atctcgtcat
    49681 gttccacata ggcattgtag cccgcctcct gctctaccac catacgattg tagatggcaa
    49741 aaggattggc acttaacttt tgcttgagtt ggacggtgta gttgacctga taggtgtctc
    49801 cctgcctcaa gtgatggtgt atctgggcaa tggccttttc atagtctgct gcagacgtca
    49861 cttcctgcca atttgagggc aaatcaatat cctcataagt cagaggaata ggggaggtct
    49921 ctaccctatc atgaacagta aagtaaagca ggtactctcc cagtagggga tccttgtgaa
    49981 ctgctaattt ttcctcaaaa gcaggggcag cctcgtagct gacatacccc accacataat
    50041 aaccttgctc ttggtagctt tccacttgtg ccagcaaatc tgccacttct gctacatttc
    50101 tcgtttttat ctctttgata ggctgggtaa aggtgtatct ctcccccaaa atcctaaaat
    50161 caatcactgt ttttctatgc ataccttaag tatagcataa aataagaaaa ccctcatccg
    50221 caaagcagat gagagatttc aattatttaa agattgaagt tttaaagcta tttgtttgtt
    50281 gaagaagttt cttataaact ttttctttta cttgcacaag tttaccatta actttattag
    50341 taaccatatc ttcttcaaga gctttggcaa ataatgattt taattcatca tagttatgaa
    50401 tggtctcacc atcaatagta aaaggagtaa aaccagcgtt ggctttttct aacaattctt
    50461 tataatattc tttcttaaaa tcagcaaacg attggaatct gccgtcagat attttttgta
    50521 taatatattg atctccaaat tgtttccctt ctttattagc ttgagatttt aatttatctg
    50581 aagcatatcc taagaatcct ttatcatagc cataatatcc ccagagtcta aatgcattat
    50641 tcttaaatgt aacagcaccg ggtgcaccct cacttgtgtt acctgcatag atactattca
    50701 tcattttaat tcctacatag gcaatacctg gatcaaatac ttctggctta tatatattat
    50761 tattcatcat acgattagtc atcagattat tatcaactaa gtcattaaca ctgtttaatg
    50821 ttattccttt ccaatcatca gagctcatat ttcgaacctt gtcatattga tcttttgacc
    50881 ctacagtgcg ttcaatagga tcaactttct taaaccacag ttgatttaat ttatcatcat
    50941 gtttactaat gactgcatca ccttcaacat aatcaagaag agacaaggta tctatatagc
    51001 ctttcatata attatcaatg tcttctcttg ttttaagagt cttcggatcg gtaatatacc
    51061 actgatttcc atcatttgga cgatagaaag tcatattaat tcccaaagca ccgtattcat
    51121 caaaccatgt acttggtact ggtgtttgta acattccttg tgcataggct tctgcatgag
    51181 tccctgagcg acgtccatat cctcctaaat agattgcacg atcattaaca tgagtagttt
    51241 catgtgtata aacagagatt ccaaactcat caatcatact taatgcaata taatttactt
    51301 ctgttcgcgt atccaaagga ttatcccaaa taactgcata agcacctgtt ccattgttac
    51361 cataatactt accaataggt ccaaacaact ctctcaatgg ggcatagtct tctttattat
    51421 ttctcttacc atacttatca ggccatccac caggtgcttg ataaccttcc caaagaggag
    51481 ttactgtatt tttgactagc atattcttaa ccttatctaa agataatcta taccaaaaat
    51541 caaaataatt tcgataactg tccgctgctt tttcaatctg attttttatt ccatcgaagg
    51601 agctatgccc taacttttct gctgttccaa cagccattgc actataattc gagattaaat
    51661 acacatgtga tttatttaga tttaataatg ggagtatcat cttccgatga gtagcagatt
    51721 gtaaattatc ccaaacttta tatttcgccg ctttaatttc atcgacttcc gaagcacgct
    51781 ccgctatata gacattccct tctgtagctt tcttaaacca atcataaata tttacatctg
    51841 cagtaaatag tcgacgatta taatttaaaa agtttaccaa attttctgat aaggttgtct
    51901 tagaaataat ctcgctgaaa gcatcatatg tccgatgacc ttttatatta tcttctcttg
    51961 aaccgatttc aattaatcta tctaatacac ttacattttt accatagaaa tctggtttga
    52021 ataacattaa ttctttaatg ttaacatcac cgaatttaac accgtagtaa cggtttaagt
    52081 atgttaaacc taataatagg gcagctttat ttttctcaac tttatcaaga atcatttgtt
    52141 gagctgcaga tgaattattc agttgatgat cttcattttc aactaattta gttactaata
    52201 tgtttaaatt agcttttaca tggtcaaaac tttcttctaa ataaaggtct ttaattgcat
    52261 ttactctatt agaccctgtt ctgccaagtt tttggtaaat tggattagat tgaagctcaa
    52321 tagggcttaa gatatttacg ataccgttaa ttaaagcact atgatctttt tgaacgatat
    52381 taggtgtata tttaatacct aagtcagtta tagtgtattc tctaacatta cttagacctt
    52441 catcactaga agataggttg aagtagtctt ttgttccatc agcataatga acgataattt
    52501 tgtttgcatc acctaaatca gttacaaagt tattattgtt cataggagta accgatagaa
    52561 tctctttagt atttaacttg ttgttcttat ctagtttatt agcttgatta acgataaaat
    52621 ctttgttata gaatggttgt agtttttcaa tattcttata agcaagttta tagtctgcat
    52681 tataatcttg aatagactcg taagctgctt cacgactgct aacattattc aatttgttca
    52741 attcataagg ttcacttacg aatttagcag cagtaatatt gaaactagca acttttgcat
    52801 cagcctcaga tttagataag tgttttaatt tatttttgtt tttattatct ttaccagttc
    52861 catcttcaga agagctatat ccaataactc caaataaatt agacacaaaa ggatttgcat
    52921 ctccatcatt aacatcgttt gaaccgaata tttcctgacc tttaataact ttcgcatatg
    52981 ttacattatc ttgaaccgct ccatatggcc aagttttaga ggttattcca ccaacatatt
    53041 tagtattttt aacatcaaga ataccttttg ctacagagtt tgtaagtttt ccttttgtcc
    53101 ctgatagcca gctatgagct ttatattgaa cgaaaggaac aagcatactt gcatttgcgt
    53161 tatttgctgt aatagtagca tcaacgtagg ctctattaac aaaccccata tagttagaac
    53221 cggcaatacc tccaactgtt gaattattac cagcagaatt tatactaccg ataaatgcca
    53281 cattttctaa agtagcgtct tcttttatgt tatttacgaa cccagcaaca ttatttctag
    53341 ctgttatggt tccgattgct ttgatatttt ctatacgtgt cgttccactg atttcatttg
    53401 ctattgcagc gatattatct tgattagata aatcaatatc aatattttca aaatttatat
    53461 ttttaacagt tccagcctta atcttatcga ataaaggatg ttccaaatta tggatagcat
    53521 agcgtttatc accatcactc aatagtttac cagtaaactc tgaagtaata taagatttcc
    53581 ctttaggaac aacgttacga gcgctcatgc tttgacccag tttaaattca ccggcaggat
    53641 ttgtctgaat ggcttggatc aattcttcaa agtcgtagaa aataccagcc tgactagctt
    53701 tgggtttttc aatatagtag gtataagttt cttcaaagcg attatcgaca ttacgttgga
    53761 ccaagttatc cgctactgct attaccttgt agacttgttt tccatcaatt gttgactctt
    53821 caattttttg aaccgctagt agattggtct tatggtcatt agaggtaact tttaaataat
    53881 aatttgacaa atcagttggc actgaagtca atcgagtttc atcagtttca acttggtttt
    53941 catatttgat taaatccgtt cttataatat cttttatttc aacttttttg agatcaattc
    54001 ttagcggttc ttctttcaga acttcttcct catccccctc accacggtca taaaccatct
    54061 ttgtttcaag tttataatcc ttgtagtact gcaaatctgt cagggtagtt gtcaagtctt
    54121 ctggtgaaac attcaaggtt ttgacaatct catcaccttt tttcagagtt agggtaatag
    54181 atttaatggc tgccttactt ggattttcta aactatactt aacatctgaa gtacgcttca
    54241 aatccttaga ttcaatttct gtgatggtca acactggttt ttcaaagctc ttggtaccac
    54301 gtttcaaaat tttgtcttga ggttcctcaa ggatttcctc tgtaactttt ggagcgtctt
    54361 ctgttttaac tcccttaatg gtattaaagg tcttggtgat ttttttctgg ccttcttttc
    54421 cttcttgagc tacaacttct aagccttttt tcagttggtc atcttcttta acaacttcct
    54481 taaatggaat cttttcaaga ctttcttcta taagagttcc ttcaattggt tttgtaccac
    54541 ggattacctg ttgatttaca ggctccttgg tcacttccgt actggttgaa agaacttggt
    54601 cagttttaac accttctact gttttatagg ttgtttttgt aacttgactt cctttttcac
    54661 cagttcgtag gacagtttct tcgtccgtat acttggttgg atcctcagtc gtttcagttt
    54721 tgtagtctag gtctgtagtc gatgtttcaa caagggttcc ctcagttact ttgtactcag
    54781 gtaattgttc ttgagcaaga gcctcaccca cgtgaccttt ttcttgcgta cctttagctg
    54841 ttttagtctc ctcttttgat tctactggtt cttcaacctt gatttctggg gcttctgctg
    54901 gctgttcatc ttcttgtttc ggtgtctctt ccgctcccct atcttcttta ggattttctt
    54961 gttgtgatga ttcttttggt gtacttggtt gctcagcttg tgtaggttgc acgggttgtt
    55021 ctgggacttt tgcttgttct actggtggtt caacttttga ttcctcagct ggtttgtctg
    55081 atggttgact ttctggctta actgctactt tttcctctgg ttttgactca acttctccac
    55141 ctacttcttc aactggagct ggttctgctg aatcttcttt cccctcttct actttaggaa
    55201 gggtgtcgtc agtaggtttt acctccgatt ttggttcttc ctttggactt tcttctgttt
    55261 taggtgcttc ttcttttgga gcttcctctg tctctactac ttggttttct gtcctagctt
    55321 gctcctgatt tgttgttgat tgaggagtct caacttcgac tacagtcacc tctccaggtt
    55381 ttgctgaggt ttcttctaaa acagtgtcca agccaagcgt tttgaggatg tcacctgata
    55441 gataaccaac atagcgatag ccatccattt caacaacacc ctctcgacta gccagcgcta
    55501 gggtcgcaac tgggtctaca gcccctgcac taggaagaac taccaatccc atagctccaa
    55561 ctagaaagac gctagcaatt ttctttctct tgtagattaa aagcaagctc ccaacagtca
    55621 gcaaaccaaa agctgtcaaa acagatgctt ctgtccctgt ttgaggaaac tgatcttttt
    55681 gatacaccaa accatataca acttcattcc tgtcaggctt tcctgtctga attaaatctt
    55741 tagcttcttg tgaaataatc tctttattta catagtgata ggtggctgcg tccactacag
    55801 aaggagccat caaaaggctt ccaagaaata cagagcctac aactccctta atcttacgaa
    55861 ttgaaaaacg gtctttttta aacactttta tctcctttat tcattctcaa gactttctaa
    55921 tagcatcttg cggatagtgc gcacgcgcac ctccgattaa ttttggacga ctagccagtg
    55981 ccgttacatg ggcatgacca atctctctca aaatagggcg aatcggaacc tgaacatgct
    56041 tgacatgcat gccaattgca gtgtctccga tatccaatcc agcatgagcc ttgataaatt
    56101 caacctcaac tggatcctgc ataaacttaa aggctgccaa ctgccccgaa cctcctgcat
    56161 gaagagtagg atggacactg acaatttcca gatcaaactg ctctgccacc tgacgttcaa
    56221 caacgagagc ccgattgaca tgctcacaac cttgaactgc taaatggata cctctactac
    56281 ctagaatacc caagatagtc tccactatca gctcaccaat ctcttgactg gattctttcc
    56341 caatctgacc acctagcacc tcactagaag atagacctaa aacaaaaagg accccctgct
    56401 tcaaattggt cttttctaaa acatcttcca ctacctgacg tgtttctctt tgaatctgtg
    56461 tctcgttcat ctctgttacc tctgttgtta ctcttctatc ataccgtttt ttcttgtttt
    56521 tagcaagata gacaacctag aaagcttgcc caattacgca taaaactccc agaattgact
    56581 gggagttagc tagtttctat tctatttata tatatttcaa ctttcgtccc tttttggggt
    56641 ctagaatcaa tcttcatctg gtaattggct ccaaaatgaa gtttgagccg ttgatcgaca
    56701 ttttgaagac caactccccc acgtttgagt tgactttgac tactatcacc agcatcttgg
    56761 aagccaacgc catcatcctc aatacggatg accaatcccg aatcctgttt ctggacagaa
    56821 agtttaatat ggccctgacc ttccttttcc ttaatgccat ggtaaagagc attttctaca
    56881 aggggttgta ggaccagctt gggtaagact aaattatcaa aggcaacatt ttcattaatt
    56941 tcgtattcca gcttatctcc atagcgttgt ttctggataa agagatactg gcggacatga
    57001 ttgatttcgt cagagagaca aatcaagtct ttgccttgat tgagcgccaa gcggaaatag
    57061 gttgccaagg acttggtcac ctgcaccact cgctgactat catgaaattc agccatccag
    57121 atgatggtgt ccaaagtgtt atagaggaaa tgtggattaa tctggctcga aagggcttga
    57181 agttggtact gacgggtcgt ttcttcctgg ctacgaatag ctaccatcaa ctgatcaatc
    57241 tgatccaaca tggcattaaa ttggcgagtt acttctctca gttcataggc accaacttcc
    57301 ttggcacgaa gattttgagc accagaagca atttccaaca tggtttctct caaatccttc
    57361 aaaggagcaa tccagcgttt aagactgaac cacactaagc agagacaaac aagaagagat
    57421 gtgacactgg ccccaagcaa ggtccacaag agctgactcc gaacctggtc taacttttcc
    57481 aatgatgaca cgccaagtac cgtccaatca gttcctgcaa tcttctcttg actgacgtag
    57541 gatttgtgac caggagtata accctgacct gtctcgatgt agggtttcat agcctccatt
    57601 ttgctagacg aactataaac tgtgtgttga ggatggtaga caaattcatg gttttcattg
    57661 ataatgaagg caaagccctg ctgccccaac tggagttgat tgagataggc ttccagagtt
    57721 tcataagaaa tatccaaacg aagcacacca agattggctc cctttgcatc aacaagttct
    57781 tgagtgacag aaatgaccca ctgactatct gatttacgag ctggagtcaa aacaggcata
    57841 gctccctgat gaatagcctt ttggtaccaa tcctcagcca tcatatcaga ggaagttttc
    57901 atctgcacac tgtcatctgt agaaatgacc tgaccagatt tggtcaccag cacaacagtt
    57961 ttcaagtcct tatctgactt caagatggtc aaaaacaaat ctcggattcc ctcgaccttg
    58021 tcttgactgg gattctcagc ataggccaga acatccgtct gctgggtcaa accagtcgag
    58081 gtggtttcta gttttttgat ataagactga ataaagtggc tagtctggct gatggtcgtt
    58141 tggctgttgc cctcaatggt ggcctcaatg gctgaagaac ttgattgata gtagaaagtt
    58201 ccaaccagag ctaggagaat gagaaagacc agaaagatgg aaataaccat tctaactaaa
    58261 agagaagaac gcttcatcgg tcttctccct tcttaaactg acgaggtgtc acacctgcaa
    58321 tctgcttaaa acgttgggta aaatagttca tatcttcaaa accaaccttc tctgcgatct
    58381 cataaatctt cagatctgta gttaaaagca agagcttggc ttgtttaaca cgttctctca
    58441 ccagataatc ctgaaaaggc aagcccaact ctttcttaat caaggaactc agataggtcg
    58501 gactaaaacc taagtcactg gctaaagact ttaaactaaa ttggctatca gccagatgag
    58561 actggatttt ctgggccatg tttccttcaa acctattagt caataaatct tgtaactgct
    58621 cttctttctc ttccttgtct agtttttgtt tgattttccc caacatttcc tcaatatcct
    58681 gacgagaaaa gggtttgagc aggtagtcgt ccacacctag tttgacagca gacaaggcat
    58741 aatcaaaatc atcgtaacct gttaaaaaga ccaaatgaac ctgaggatag gtttctcgta
    58801 ccagactggc caactggatg ccatttagat gaggcatgtt gatatcggtt aaaatgatat
    58861 ctggcacctg cttttggatc aattcccaag cctgccttcc attttcagcc tgaccgatga
    58921 tttccatatc gtaggctgct acattgacca gtttagtcaa accttgtctt accagatatt
    58981 catcttctac gattaagatt gtgtaggtca tgctctgctc ctttaccact tactagtatc
    59041 agtatagcaa aattctcctc taactgctta ggaaagacct cttatactca ataaaaatca
    59101 aaaagtaaac taggaagata gccacaggtt tctcaaagta tagctttgag gttgta
//
LOCUS       DAVBOU010000008        59064 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBOU010000008 DAVBOU010000000
VERSION     DAVBOU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.008"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ879_000472"
     CDS             complement(181..1359)
                     /locus_tag="VQ879_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3142690.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ879_000473"
     CDS             1639..2901
                     /locus_tag="VQ879_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3142691.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ879_000474"
     CDS             2904..3800
                     /locus_tag="VQ879_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3142692.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ879_000475"
     CDS             3815..4132
                     /locus_tag="VQ879_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3142693.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ879_000476"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ879_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ879_000477"
     CDS             4475..5077
                     /locus_tag="VQ879_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3142694.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLRVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ879_000478"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ879_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ879_000479"
     CDS             5624..6394
                     /locus_tag="VQ879_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3142695.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ879_000480"
     CDS             complement(6672..6959)
                     /locus_tag="VQ879_000480"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3142696.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ879_000481"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ879_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ879_000482"
     CDS             complement(7545..7748)
                     /locus_tag="VQ879_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3142697.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ879_000483"
     CDS             complement(7779..8387)
                     /locus_tag="VQ879_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3142698.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ879_000484"
     CDS             complement(8426..8596)
                     /locus_tag="VQ879_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3142699.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ879_000485"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ879_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3142700.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ879_000486"
     CDS             complement(9258..9422)
                     /locus_tag="VQ879_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3142701.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ879_000487"
     CDS             9865..11346
                     /locus_tag="VQ879_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3142702.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ879_000488"
     CDS             11708..12703
                     /locus_tag="VQ879_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3142703.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ879_000489"
     CDS             12830..14140
                     /locus_tag="VQ879_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3142704.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ879_000490"
     CDS             14236..15138
                     /locus_tag="VQ879_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3142705.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ879_000491"
     CDS             15140..15985
                     /locus_tag="VQ879_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3142706.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ879_000492"
     CDS             15995..17314
                     /locus_tag="VQ879_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3142707.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ879_000493"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ879_000493"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ879_000494"
     CDS             complement(17861..19132)
                     /locus_tag="VQ879_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3142708.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ879_000495"
     CDS             19402..19641
                     /locus_tag="VQ879_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142709.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            19806..19985
                     /locus_tag="VQ879_000496"
     CDS             19806..19985
                     /locus_tag="VQ879_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142710.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            20122..20300
                     /locus_tag="VQ879_000497"
                     /pseudo
     CDS             20122..20300
                     /locus_tag="VQ879_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            20337..20789
                     /locus_tag="VQ879_000498"
     CDS             20337..20789
                     /locus_tag="VQ879_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3142711.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21080..21550
                     /locus_tag="VQ879_000499"
     CDS             21080..21550
                     /locus_tag="VQ879_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3142712.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            21569..22657
                     /locus_tag="VQ879_000500"
     CDS             21569..22657
                     /locus_tag="VQ879_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3142713.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            22638..23066
                     /locus_tag="VQ879_000501"
     CDS             22638..23066
                     /locus_tag="VQ879_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3142714.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            23201..24154
                     /locus_tag="VQ879_000502"
     CDS             23201..24154
                     /locus_tag="VQ879_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3142715.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            24156..24899
                     /locus_tag="VQ879_000503"
     CDS             24156..24899
                     /locus_tag="VQ879_000503"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3142716.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            24910..26706
                     /gene="pepF"
                     /locus_tag="VQ879_000504"
     CDS             24910..26706
                     /gene="pepF"
                     /locus_tag="VQ879_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3142717.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(26766..27443)
                     /locus_tag="VQ879_000505"
     CDS             complement(26766..27443)
                     /locus_tag="VQ879_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3142718.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            27690..28460
                     /locus_tag="VQ879_000506"
     CDS             27690..28460
                     /locus_tag="VQ879_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142719.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            28453..29217
                     /locus_tag="VQ879_000507"
     CDS             28453..29217
                     /locus_tag="VQ879_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142720.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            29641..30432
                     /locus_tag="VQ879_000508"
     CDS             29641..30432
                     /locus_tag="VQ879_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3142721.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            30543..31211
                     /locus_tag="VQ879_000509"
     CDS             30543..31211
                     /locus_tag="VQ879_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3142722.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ879_000510"
     CDS             complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ879_000510"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3142723.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(32303..32617)
                     /gene="trxA"
                     /locus_tag="VQ879_000511"
     CDS             complement(32303..32617)
                     /gene="trxA"
                     /locus_tag="VQ879_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3142724.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(32634..32855)
                     /locus_tag="VQ879_000512"
     CDS             complement(32634..32855)
                     /locus_tag="VQ879_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3142725.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(32954..33334)
                     /locus_tag="VQ879_000513"
     CDS             complement(32954..33334)
                     /locus_tag="VQ879_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3142726.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(33477..34430)
                     /locus_tag="VQ879_000514"
     CDS             complement(33477..34430)
                     /locus_tag="VQ879_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3142727.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(34498..35706)
                     /gene="sstT"
                     /locus_tag="VQ879_000515"
                     /pseudo
     CDS             complement(34498..35706)
                     /gene="sstT"
                     /locus_tag="VQ879_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            35845..36405
                     /locus_tag="VQ879_000516"
     CDS             35845..36405
                     /locus_tag="VQ879_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3142728.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            36462..37370
                     /locus_tag="VQ879_000517"
     CDS             36462..37370
                     /locus_tag="VQ879_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3142729.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            37322..37912
                     /locus_tag="VQ879_000518"
     CDS             37322..37912
                     /locus_tag="VQ879_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3142730.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            37915..39021
                     /gene="yqeH"
                     /locus_tag="VQ879_000519"
     CDS             37915..39021
                     /gene="yqeH"
                     /locus_tag="VQ879_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3142731.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            39235..39546
                     /gene="yhbY"
                     /locus_tag="VQ879_000520"
     CDS             39235..39546
                     /gene="yhbY"
                     /locus_tag="VQ879_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3142732.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            39598..40227
                     /locus_tag="VQ879_000521"
     CDS             39598..40227
                     /locus_tag="VQ879_000521"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3142733.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            40227..40820
                     /gene="yqeK"
                     /locus_tag="VQ879_000522"
     CDS             40227..40820
                     /gene="yqeK"
                     /locus_tag="VQ879_000522"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3142734.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            40821..41321
                     /locus_tag="VQ879_000523"
     CDS             40821..41321
                     /locus_tag="VQ879_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3142735.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            41334..41687
                     /gene="rsfS"
                     /locus_tag="VQ879_000524"
     CDS             41334..41687
                     /gene="rsfS"
                     /locus_tag="VQ879_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3142736.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            41790..42536
                     /locus_tag="VQ879_000525"
     CDS             41790..42536
                     /locus_tag="VQ879_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3142737.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            42546..43643
                     /locus_tag="VQ879_000526"
     CDS             42546..43643
                     /locus_tag="VQ879_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3142738.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            43990..46737
                     /locus_tag="VQ879_000527"
     CDS             43990..46737
                     /locus_tag="VQ879_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3142739.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            47080..48693
                     /locus_tag="VQ879_000528"
     CDS             47080..48693
                     /locus_tag="VQ879_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3142740.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            48823..49449
                     /gene="gmk"
                     /locus_tag="VQ879_000529"
     CDS             48823..49449
                     /gene="gmk"
                     /locus_tag="VQ879_000529"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3142741.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            49474..49788
                     /locus_tag="VQ879_000530"
     CDS             49474..49788
                     /locus_tag="VQ879_000530"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3142742.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            49854..52250
                     /locus_tag="VQ879_000531"
     CDS             49854..52250
                     /locus_tag="VQ879_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3142743.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            52263..53198
                     /locus_tag="VQ879_000532"
     CDS             52263..53198
                     /locus_tag="VQ879_000532"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3142744.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            53191..54504
                     /gene="rsmB"
                     /locus_tag="VQ879_000533"
     CDS             53191..54504
                     /gene="rsmB"
                     /locus_tag="VQ879_000533"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3142745.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            54519..55259
                     /locus_tag="VQ879_000534"
     CDS             54519..55259
                     /locus_tag="VQ879_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3142746.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            55256..57235
                     /gene="pknB"
                     /locus_tag="VQ879_000535"
     CDS             55256..57235
                     /gene="pknB"
                     /locus_tag="VQ879_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3142747.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            57350..58108
                     /locus_tag="VQ879_000536"
     CDS             57350..58108
                     /locus_tag="VQ879_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3142748.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            58110..58559
                     /locus_tag="VQ879_000537"
     CDS             58110..58559
                     /locus_tag="VQ879_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3142749.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            58621..59064
                     /locus_tag="VQ879_000538"
                     /pseudo
     CDS             58621..59064
                     /locus_tag="VQ879_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        18063 a        10290 c        12785 g        17926 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataattcc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgagag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagcggcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatggttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aatcatactc aatgaaaatc
    19741 aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggtaagg cgacgttgac
    19801 gtggtttgaa tttgattttc gaagagtatc agtttgtaaa aattggagat aaaaaatata
    19861 gagtacgcag tgttcctatg attcattcaa ctccgcctca atctgtctta gatcgagata
    19921 cttttacaat tgactataca gatgatgaat tgctcgataa agaagcagtt tttactactc
    19981 attagaaaaa taggtatgaa taaattggct tcccttagaa ccacatctag gggcttttat
    20041 gtataataga ataataagta tcactccttt acaatacgtg taacacgtgt tataatggtg
    20101 ttgtcaggag gtaaaagcgc tatgcctatg acacaaaaag agatggttaa actccttacg
    20161 gcccatggtt gataaagact agaggcggta aaggttccca tattaaaatc gagaagcaag
    20221 gggaaagacc tatcacaatc cctcatggtg agctgaataa gtacactgaa agagggataa
    20281 gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt agtgaaatgt
    20341 tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa gcgacttatt
    20401 ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt tctgaggctt
    20461 tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag agtgatggag
    20521 agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat ccttttaaag
    20581 atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct atggtatctg
    20641 ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg accataccaa
    20701 aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact ttgacagacg
    20761 ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt aatagtcaat
    20821 aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat ttattagccc
    20881 tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact tttaagaaaa
    20941 tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata aaataatttt
    21001 gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg attaaagagt
    21061 cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag aggaagagtt
    21121 ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc atgcggtaga
    21181 agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg
    21241 agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca atcctgccaa
    21301 gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta aaaaaggatt
    21361 ttctcgcgag tttttagctt attttgccct tttcctcaaa gatactgcgg aggttgggct
    21421 agataccctc atggactttt tggaagatcc agaagcagag gaatttgtta tggaatggaa
    21481 tcaagaagtc tttgaagaag gaaaagttgg cttggaagag ggagaatttt atccttatcc
    21541 aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt tggtttatgt
    21601 gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt
    21661 ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc taagcatgta
    21721 tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga caggctatcg
    21781 gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca ggtttcatct
    21841 tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa aagaggatga
    21901 aagcgatcaa agaatcatcc tgatgctttc aggaggcttg atggttcatc tcggcttgat
    21961 attattggcg atagtgtttg gctttttgac aagaagctgg tattttgcag ggacttggat
    22021 ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca ccgatggagc
    22081 aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc tggtattgag
    22141 acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact ttgttcaagc
    22201 agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt
    22261 ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat tacttgagag
    22321 gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata tcgccttgtt
    22381 ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca aatcgtttct
    22441 gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa
    22501 agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg atagtagtcg
    22561 aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg aaaaggaaat
    22621 gttagaagga actgaagatg gaactagaaa tttctgattt ccaaggttgc aagattgccc
    22681 tcttttgtgg ggataagcta ctgacgattt tgcgtgatga caaggacgat atcccttgtc
    22741 ccaacatgtg ggagttgcca ggtggtggcc gtgaagggga cgaaagccct tttgaatgcg
    22801 ctcggcgtga agtttatgag gaactgggaa ttcatttaga tgaagactgt ctgctttgga
    22861 gcaagattta tcctagcgta atttttaaag gcaagaaatc ggtctttatg gttggtcagc
    22921 taagacaaga acaatttgac aatatcatct tcggagatga aggacagggc tatcagctga
    22981 tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa gagagattaa
    23041 aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct aaactgaacc
    23101 cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaagcgtc ttcagagaat
    23161 ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa catggcaaga
    23221 gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct tgattgagct
    23281 gggagcgcaa ggtgttgcga ttgaagacag tatggactat gtgggaaatg ttgaccgctt
    23341 cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag cctactaccc
    23401 tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat cagaattgac
    23461 ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg aggaagactg
    23521 ggcagataac tggaagaaat actatgagcc agctcgtatc actcatgatt tgaccatcgt
    23581 tccctcttgg acagactatg aggcgactgc gggagaaaaa attatcaagc tggatcctgg
    23641 catggctttt ggtacgggaa cccacccaac taccaagatg agcatttttg ccttggaaca
    23701 ggttcttcgt ggtggcgaaa cggtgctaga tgtgggaact ggttcagggg ttctctctat
    23761 tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg atgtggcagt
    23821 tcgtgtggct caggaaaata ttgagctcaa ccctggaatg gaaaatatcc atgtagcggc
    23881 aggcgatttg cttaaaggcg tggagattga agcagatgtc atcgtggcaa acatcttggc
    23941 ggatatcctc attcatctga cagaggatgc ttatcgcttg gttaaggatg aaggttacct
    24001 gatcatgagt ggcattatca aggataagtg ggacatggtg cgcgagttgg ctgaatcagc
    24061 tggatttttc ctcgaaactc acatggttca aggggaatgg aatgcctgtg tctttaagaa
    24121 aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt gtaaaaggca
    24181 gtgctatctc tcctgtcact atcgagaaca aggaaaccag taagcatatg tttcaggtta
    24241 tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc aagcgcttgg
    24301 cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta aatgacaatg
    24361 tggaactacc agttcaagtg accatcgcat ctggatttcc caagggagac aagctggagt
    24421 tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt cctgcagact
    24481 ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa
    24541 ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt aaacttttcg
    24601 agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata gtagcctatg
    24661 aagaatcagg taaagaagga gaagccgctg cgcttctgca agcagtcact ggtcttgaaa
    24721 caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct gcagaaatcg
    24781 aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt ttgcgagcag
    24841 aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta gagaaataag
    24901 aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact ctgggactta
    24961 acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac
    25021 atcaaccagt ttagccgtga ttacaagggc aatcttcaca cttttgagga tttcgagaag
    25081 gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa ctatgctttt
    25141 atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca agctgggatg
    25201 gaatttgaaa cagctgccag cgtagccttg accttctttg acgatgcctt ggtggcagca
    25261 gacgaggaag tcttggaccg tttgggtaaa ttgccacatt taacagctgc cattcgtcag
    25321 gctaaaatca aaaaagccca ctacttaggg gcagatgtgg agaaggcctt gacaaatctc
    25381 ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg ggattttgaa
    25441 atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac ctatgagaat
    25501 ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc cttctcagag
    25561 ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt caagtctgaa
    25621 aaactcttgg ctgatatgaa gggatatgac tctgtctttg actatcttct agctgaacaa
    25681 gaagtggacc gtgtcatgtt tgatcgccag attgacctca tcatgaagga ctttgcacca
    25741 gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt
    25801 gcagactgga aattggactt ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc
    25861 tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca ggaagttgct
    25921 cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga ttccggtggt
    25981 tatgcagcgg acccatatcg cgtacaccct tatgtactca tgagctggac aggccgtttg
    26041 agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat cttttcagac
    26101 aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc accgtcgacc
    26161 ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc acgtcaaaaa
    26221 cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat cacccacctc
    26281 ttggaagccg ccttccagcg taaggtgtat acattgattg aagaaggaga aaccttcgga
    26341 gcaagcaaac tcaacagcat tatgaaggaa gttttgacag atttttgggg cgatgccatt
    26401 gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta tatgggcttg
    26461 tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct tcatcttaaa
    26521 aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg tagcaagaca
    26581 ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc actccgtgat
    26641 accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc tgagttgggg
    26701 gagtaagggg atagagaggt tgttatagaa tgggtatgga cagttatttg cttaaaagtc
    26761 catgtttaaa tcccccattc cttttcgagg aattctttgc ccttctctgt aatggtaagt
    26821 gaacgtggcg tttgtgcagg gatgaccaat tgtttttcac tgaaaaattc taaaagagca
    26881 ttgccgagag ctccgccgac atgattttta cgttcgctcc aatccaaaca tttagggcaa
    26941 aatttccgtt ttttcttttt caattcatcc gtatcaatgt gtaattttct ttggaaataa
    27001 gacttcccag cttcagtgag ttggaagtct ttttctgatt cgctgaggag attttcttgc
    27061 aagagataat tggtaatgga aatgccaagc tcaccagcaa tatggtcata gcaggtgcga
    27121 gcgaccttta attccttttt gtgaatgtgt tgtttataac ttttgacatc acgctgagga
    27181 gagtagaagc tgagaaattc cagcatttct gcaatggcag cactttttaa agaataataa
    27241 tgaaaacgtc cataggtttg tagagtggtt acctgcgctt cggtaagtaa tttgaggtga
    27301 tagctgacag tatgttgctt gattttggta aagctggcaa tttcgttaac cgtgtgagct
    27361 tttccatcca ttagaatatc taaaatgtgc atccgagaag ggtctgataa gagttttgtg
    27421 atgatgaaaa tatctggttt cataaaaatt ttctccaaat ttcatatatc gatgattttc
    27481 tatcttttat tatactataa ttaaagcaca agaaaaatag attttaaaaa tgttttacta
    27541 gagaatattt taaattttat tgtctgagtt taaatggagg taaaattaca aaagtaattg
    27601 cagcagtatc cacagttgaa ggacgttaat cttaagatta cattctcaac attttttcaa
    27661 aagtgagatg aattaacaaa gtatccaaca tgctctattt gtgggggaaa gaaagagtga
    27721 agaagttaag tgttaaaaat ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa
    27781 ttagctttga attgggagac ggagagtgtt tgggtatctt gggaatcaac ggtgctggca
    27841 aaacatccac tttaaagatg atttactcac tgacctcaat ttcctcagga gagattgata
    27901 tcttggggca aaatattgaa accaatcgtc gtaagagtaa atcttgtctg ggtattgtag
    27961 ggcaggagga tatgctggac atgaccttga atgtttatga taatcttttt gctcacggtc
    28021 tatgttatgg tatctcatct gtcgaactta ggaagagaat cgattctctc ttggattttg
    28081 ttcaactgag caaacatgcg caaaagatgg tgaatcagct gtcgggtggg atgcgacgac
    28141 gtcttgtctt ggcaagagct ctcatcaatc ggcctgatat tatcatttta gatgaaccga
    28201 cagttggttt agacattcaa tcccgcaata ttatttggga taaacttttg gaattgaagg
    28261 aattaggtgt ttctatcatt attacttccc actatatgaa tgagattgaa tatttgacag
    28321 atagggtgct gatgctccac caagggacta tcaaagaaga aggaactgta gaagacttgc
    28381 tcatcaagta tgatgctgac aaccttgaga cgcttttttg ggggttgact gggacagaga
    28441 aggaggactt gcatgtttaa gttatcattt cactccatcg gacacgttgt ggtacgcaac
    28501 tacatgagtt ttagaaattt atttaaaatt tcaattgtcc ccaaccttat cgaccccctc
    28561 ttttatcttt tagcaatggg atttggagtt ggtgcttatt tgacgcatgt taacggtatg
    28621 ctctaccgtg attttgtcat tacaggttta attgctgcga ctgccatgtc tgcggccacc
    28681 gcagaaacaa cggtcaatgc ctttatccag tataagattg aaaagactta tgatgctatg
    28741 ttgatgacgc caatcaatac gaatgatatt gtggtaggtc aggctatctg ggcaggtatt
    28801 cgtgcagtga ttttcggtgg gattttttgg ctgatttcca tgcttatcac agcgcatttt
    28861 catgtcttga tgttattgat tcctctgatt ttatttatag tgggttattt gtttggtgtt
    28921 ttgggactaa tctttaccta cttggcgccg tctagggaat ttctgaatta ctacaatgtt
    28981 ttggtaatcc gtcctcttta tatgttttca gataccttct ttcccattac ttccttgccc
    29041 ccaatacttg gtgatttgac ttggttttct cccttgtatc acgctacccg catgattcgt
    29101 attatatggg gaggtgaggt gacaggtttg tatcttcatc ttatctggtt gatagccttg
    29161 gcgctcttga taacggtgct tcctatgtat atgttacatc gtagatatta tagatagtct
    29221 aattatttgt gatgttgtag tcatattcta atttatacta aacgttattc gaatttggac
    29281 aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata gtacggttca
    29341 gtttttaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    29401 tcactttatt ataactagtt tttcgcaatt tttgagacag gaatgtgatt tttgtgataa
    29461 ggttctatca ttacaagttt atttgttgta atatggaata aatcatttat atatcttttc
    29521 agaaatatgc tgtttctctg aatataaatg tctttttctt tttaacttaa ttttacaaat
    29581 tggtaaggtc atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc
    29641 atgtatcaag atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa
    29701 atccagtggt tgcttgatca tttgggagat ccttctccag aaattcgtga tgatcttgtt
    29761 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggagca atttcatttc
    29821 attgctgagg tggtcttagc tgatggaggg ttagataaag agattgataa ggtaggcttg
    29881 tcaacacttg aacgttcttt tagggcactt gtttatgcaa atctcttgtc tgtagatgct
    29941 aaccagcaat cggtttttta tcagggatta caatcagaaa ttcgtaatgt ccttttaaat
    30001 caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt
    30061 tgggttcacg cttttgcaca tggagccgat ttactgaaag aggtggtttg tcatccagac
    30121 tttcctaaaa acagagttca tgaagtattt gatatacttg gccaactatt taaaagaatg
    30181 tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt
    30241 ttacaaggga agttagcgca agaacaagta gcttcttgga taaaaactgt tgattttccg
    30301 atagaagaaa gggaggattt ttacaaattt tccaacttca gaacctgtct gttggaagtc
    30361 tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct
    30421 tttcaatact agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt
    30481 cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga
    30541 aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtattc gtcgggacag
    30601 gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc gcctttgcct
    30661 ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga
    30721 atccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa
    30781 actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgcagtc ttcttcctct
    30841 tgggtaattc aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca
    30901 ctgtctttgg tggtttcttg tttgaagtca tcgcaacttt cttgtttgtc ttagttatca
    30961 tgactgtgac ttcagaaagt aagggcaatg gcgcgattgc tggtttggta atcggtttgt
    31021 cattgatggc gatgattctt gtcggattga agattactgg actttcagta aacccagctc
    31081 gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca
    31141 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    31201 cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    31261 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc ctaggtatgg
    31321 ttactgactt cgtcagttct atctgcaacc tcaaaacagt gttttaagct gacttcgtca
    31381 gttctatctg ccacctcaaa cactgctttg agtaacctgc ggctaacttc ctagtttgct
    31441 ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat aaaggtcgtg
    31501 ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac cgtagttata
    31561 gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt ctaaatagcg
    31621 agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt cgtggaaatc
    31681 tccgtgattt cggtagctaa atagatatag tttgagggat tttgactcga cacagagctt
    31741 gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga tttgtcccag
    31801 cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt ctctagtaat
    31861 ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga ctgtttcata
    31921 gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa agacgaccaa
    31981 ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag cacgcaaaaa
    32041 gctcccatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg catatcccaa
    32101 acatcgtaat attctactta tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
    32161 cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct agtttcaatc
    32221 tactatagtc tagcatattt tttgaaaaat ggcaaagagc aagaaaaaag agaccaaaga
    32281 aagtacttgg tctctcgttt gattagctca attcagcaat gatggccttg atttgttctg
    32341 ctgtgtgaac acctgcaact tgtttgacaa cttggccgtc ttttttgaag agaagagttg
    32401 gaatagacat gattccaaaa gcacgagctg tgtttggatt ttcatcaacg tccattttaa
    32461 cgattttcaa gacatcttct gaaagttctt cagacaattt gtccaagatt ggaccttgca
    32521 tacgacatgg accacaccaa gttgcccaga agtctactaa gaccaaaccg tcttttgttt
    32581 cttgttcgaa tgttgcatct gtaattgctt ttgccattgt atttctcctt tttttagtta
    32641 tattggctta aatcttgttt catgagatag aagaagatat ctccataagt cccatggtag
    32701 tccaaattat gacccttgta agttaatttt tggacagggt agtagtctgc gacgccgata
    32761 aggcaagctt gttgcgaacg ttcaaagtct tcataagact cgaaagtcac agttctttcg
    32821 ttcttgctgg catctatata ggtaatttca atcatattta aaactccttt gtttaatgct
    32881 aactttattt tactccttat aaaagagaat gtcaagaaaa atgattgcgc acgcaacttt
    32941 ttttaaaatc atcttaaatc aagaaatcca aacctgcttc caagctttct tcgacagtct
    33001 tttgtagcga ggccagtgtc ttttgcccat catttgtcag gcagataaaa ctagagcgtc
    33061 tatcttgatg gcaacacatg cgactgagta gaccgcaatt tttagcttcc aagcgagcca
    33121 ccatcctaga aactgcgctc gggctcagat gaagcttatc tggcaggtca atctggcgta
    33181 gagatttttc ttcagccaag tccagatagt agagcaggta gaactctttc aaggtcagac
    33241 tttgctcgct ctgttgggca atggtctctt ccaagagact ttcaatttct ttctgacgcc
    33301 gattgaagtc aaaccatttt tccaaatagg tcatagtgtc tcctttcttt ttagagtcat
    33361 aaatagaaga aagtccatta acgggcagtc tctgcgtcac aagatgattg cgcatgcaat
    33421 aattatacta cttttcaaga atactggcaa gctctgtttt ttagtggttt tcttttttac
    33481 tgtctatatt tttggtaaaa atcaactttt acttggatga aggttttggc ttcacgtagg
    33541 agttgaagaa gagtggcgcg ggtttcaaac tcttctcttg tcttgggcag actgcggttc
    33601 cggaagactt ccagataacg ttcaatttca tctagcaaat cagaagcagg attggtctgg
    33661 ctcagttgac ctgcaatttt tgaaaagagt tgcgctaaga tcaggctttc actggcggca
    33721 aggtgacaag tgttaatctg ttgggccatg tttctcagga tacgactttg tcgttgtctc
    33781 atctcaaagt agtggatatg gtagtcggtc tggtgaaaga ggtggtcaga gtgatccaaa
    33841 tagaccagtc tgagggcttc tttcaaaagc gtgtctaatt ctgctaccag ctgtgctcgg
    33901 ttgcgtccgt ctcctctgga taaatagtat ttgaagcgct ggaggatatc ttttaacttt
    33961 tcttccacca gcgtgtggta gtgctggatt tcctcttctc gtgaaggcat atagagatta
    34021 acaagcaagg caaatcctgt accaatagca aagagaagga attcgttgac taggaggtct
    34081 ggagaggttg actcttgaac caagagatgg ctaaccaaaa ccgtgcttgg tgtgatgcca
    34141 atttcccagc ccatcttgta ggctaaagga acgtagaagg ccagatagag gccgagactc
    34201 cagatatgaa atccgctcaa gtgaaaagct agaacgccga tagccagagc tagaagcata
    34261 gaaaaaagac gattgcgagc cagttttaaa gtacttctac gcgtatcaga taggctcaag
    34321 agagcgataa ttccagccga aactgctgac gaaagattga gaaaataagc aagcaggcag
    34381 gcaagacagg tagctaagat gagcttggtc gtacgttggc taatagacat aagaatttcc
    34441 taataagtta gaataaaagc gtaaaagaca agacatgagc aggcttgcct tgatgagtta
    34501 ttttttacgg gttgctgcgt attcggcaac ggcggtaaag aggacatctg tagaagagtt
    34561 aagggctgtt tcacatgagt cttggatgac accaatcaca aaaccaaccc caacaatttg
    34621 tatggcaata tcgttagaaa taccgaaaag gctacaagca actgggataa gaaggaggga
    34681 acctccggca atacctgaag catcacaggc tgagatagct gctaccacac tgaggacaaa
    34741 ggctgtggca aagtcaacag gaattccaag agtgttaact gtaacaaggg tcaaaacgtt
    34801 aatggtaatc gctactccag ccatattgat agtagaaccg agtgggatag aaacagaata
    34861 ggtatctggg ttgagtccaa ggtcatggca gagtttcatg ttgacaggaa tgttagtcgc
    34921 agaactacga gtgaaaaagg ctgtcacacc gctgacacgg aggcagttcc aaactagagg
    34981 gtaaggattg cgtctcataa agaagaaggc aatcaaaggg ttgaccacag gggcaacaaa
    35041 aagcatagtc gttactaata gaaccaataa aataccgtag ttggcaaggc ttccgactcc
    35101 cttgtcagaa atggttttaa aaacaagacc aaggattcca aatggagcca gattgatgat
    35161 ccattcgaca attttagaag tcacgtcagc gatagttttt agcaattctt tactattttt
    35221 actggcttct ctcatagcga ttccaaaaat gactgcccaa gataagattc taatatagtt
    35281 agcagtaagc agggcgttga ctgggttgtc aaccagtttg agcaagaggt tgctgaggac
    35341 ctgcccaatc ccatctggtg gtgcaatttc agtattggca ctatttaggg taatttcaat
    35401 agggacgatg aaacttgcta gtacagctac aagagcagcg gcgaaagtcc ctatcatagg
    35461 atatacaaga aaacaacagt tttcatattg ctatcttgtc ccttttgatg ttggaaaggg
    35521 cattggcaac gagggcaaag actaggatag gagcaacagc ttttagacct ccaacgaata
    35581 aatccccgag tagcccaatc cctgagagat taggaagggt cagtcctagg attccccaca
    35641 aagcatacca atcaagatac gcttgacaag gcttgcctta ttccaagcat gaatgattct
    35701 tttcataata atctcctttt tgtgtagtga ttatgattat agtataaatg atagacaaaa
    35761 tcaagaattt tctgtctatt ttttgaatat ttatggagaa tgagactgat gaaaatatgg
    35821 tataatgaaa taaaggagtt ttatatgcaa aaatttattc aggcttatat tgaaaagcta
    35881 gatgtgacaa ccattatcga gaatattcta accaaggtca tttctctttt actgcttttg
    35941 attgtatttt atattgctaa aaaaatgctt cataccatgg tgcagagaat tgtcaaacct
    36001 tctctaaaaa tgtctcgtca tgatgtcgga cgccaaaaaa ccatctcacg tttactagaa
    36061 aatgtgttta attatacgct atatttcttt ttactctact gcattttgtc gattttaggt
    36121 ttgccagttt ctagtttgct ggctggagct ggtattgctg gggtagcgat tggtatggga
    36181 gcccaaggct ttctgtctga tgtcatcaat ggctttttca tcctctttga acgtcaactg
    36241 gatgtgggag atgaggtcgt tctgacaaat ggaccgatta ctgtatcggg taaggttgtc
    36301 agtgtgggaa ttcgtacgac acagcttcgt agcgaggagc aagcccttca ctttgtccct
    36361 aaccgaaata tcacagttgt tagcaatttc tcacgcacag actagacctg ttattttaag
    36421 taatttgtgg tacaatagag ggagtttaat aaggagaaaa gatggtttta gaaaagcagt
    36481 tgggcaatgg ttgtacctgg atagacctag acctaggaaa gttgaataaa ctagaagacc
    36541 tttctgaaat ttacggtttg gacaaggaaa ccattgaata cgcactggat agaaacgagc
    36601 gcgcccacat ggattaccac cgtgaaagtg ggacggttac ctttatctat aatgtcctag
    36661 acgtaaaaaa ggacaaggcc tactatgaga cttttcccat gacctttatt gtcgagcatc
    36721 gtcgcctgat taccattagt aataccaaga acgcctatgt cattgaacag atgactcgtt
    36781 atctggagag ccatgacacg ctttcgattt ataagtttct ctttgccagt ctggaaatta
    36841 tcagcaatgc ctactatcct gtcattgagc agatggacaa gagtagggat gaggtcaatg
    36901 acctcttgcg ccagcgaact accaagaaaa acctctttgc cctgtctgat ttggagactg
    36961 gtatggttta tctgacggca gctgccaaac aaaatcggat tttgttagag catattcaag
    37021 gtcatgcctt gtatcgtagt tttgatgaga ttgagagaga acagtttgat gatgccatga
    37081 ttgaggctca tcagctggta tccatgacag acctaatctc tcagatttta cagcagcttt
    37141 cagcctctta caacaatatt ctaaacaata atctgaatga caatttgaca accttgacta
    37201 tcatttcagt cttgctagct gttttggcag tcgtgacagg ctttttcgga atgaatgttc
    37261 ccttaccttt aacagatgag ccccatgctt ggctctatat cagtttggct agtgcaggtt
    37321 tgtggattgt tttatccttg ttactaagga aaattgcgaa aaaaagttaa gaaaaggagc
    37381 cagaatggcg attgaaaatt atataccaga ttttgctgtg gaagcagtct atgatctgac
    37441 agtcccaagc ctgcaggcgc agggaatcaa ggctgttttg gtcgatttgg ataataccct
    37501 cattgcttgg aacaaccctg atggaacgcc agagatgaag caatggctac atgaccttcg
    37561 ggacgcgggt attggcatta tcgtagtgtc aaataacacc aaaaaacgcg ttcaacgagc
    37621 agttgagaaa tttgggattg attacgttta ctgggccttg aagcccttca catttggtat
    37681 tgaccgtgct atgaaggaat tccactatga caaaaaggaa gtggtcatgg ttggcgacca
    37741 gctcatgaca gatatacgag cagcccaccg tgcagggatt cggtcaattt tagtcaaacc
    37801 cttggtccaa catgactcaa tcaaaacgca gattaaccga actcgtgagc gtcgtgttat
    37861 gagaaaaatc actgaaaagt acggaccgat tacatataaa aaaggaattt aactatggaa
    37921 gaaattctct gtattggttg tggagcaacc attcagacga cagataaagc tggtcttggt
    37981 tttacccccc agtcggcact tgaaaaaggt ttggagactg gcgaagtcta ttgccaacgc
    38041 tgtttccgtc tccgccacta caatgaaatc acagatgtcc agttgacgaa cgatgatttc
    38101 ctcaagctct tgcacgaggt gggagacagt gatgccttag tggtcaatgt cattgatatc
    38161 tttgatttta atggatctgt catcccaggt ttaccacgtt tcgtctcggg caatgatgtc
    38221 ctcttggtag gaaataaaaa agatatcctt cctaagtcag ttaagtctgg taagattagc
    38281 cagtggctca tgaaacgtgc ccatgaagaa ggtcttcgtc cagtcgatgt ggtcctaact
    38341 tcagcacaaa ataaacatgc cattaaggaa gtcattgaca agattgaaca ctaccgtaag
    38401 ggccgcgatg tctatgtggt cggtgtgacc aacgttggaa aatcaactct aatcaatgct
    38461 attatccaag aaatcacggg tgatcagaat gtcatcacta cttcacgctt cccaggtaca
    38521 accttggaca aaatagagat tccgcttgac gacggatctt atatttacga tacgccggga
    38581 attatccacc gccaccagat ggctcactac ttgacggcca aaaacctcaa gtatgtcagt
    38641 cctaaaaagg aaatcaagcc taagacctat cagcttaatc ctgagcaaac cctattttta
    38701 ggtggtttgg gacgctttga ctttatagca ggagaaaagc aaggatttac tgctttcttt
    38761 gataatgaac tcaaactcca tcgtagcaag tttgaaggag ctagtgcttt ctacgataag
    38821 cacctgggaa ctcttctgac accaccaaat agcaaggaaa aagaagattt cccaaggcta
    38881 gtccagcatg tctttaccat taaagataag acagacctag tcatctcagg cctaggctgg
    38941 attcgtgtaa caggcatagc aaaagtcgcc gtctgggcac cagaaggcgt cgccgtcgtc
    39001 acacgaaaag caattattta aaacaaaatc gctgagcgaa caaagtgagc tcatatagcg
    39061 atagttattg ccgtggtgtg attgccaatc tgtagattgg caaggggcac aattgagacc
    39121 aaggctcaat tgtgaggtca ggaaatccat ttttcaaaga tgaaatcttt ggaaaattag
    39181 ttccgaccgt ccctcaccac ctaaaataac tatccaaaaa caaggaagaa aattatgtca
    39241 ttaacatcaa aacaacgtgc cttcctcaac agccaggcac acaccctcaa acctatcatc
    39301 caaatcggga aaaatggact caacgaccaa atcaaaacca gcgtccgtca agctcttgat
    39361 gcgcgtgaat taatcaaggt tactctctta caaaacacag atgaaaatat ccacgaagta
    39421 gctgaaattt tggaagaaga aatcggtgtg gatacagtcc aaaaaatagg acgcatcttg
    39481 attttgttta aacaatctag caagaaagaa aatcgcaaga tttctaagaa agtcaaagaa
    39541 atctaagacc gaaactccaa ataactgttt ttatagagaa ataaagggga ctagcctatg
    39601 acaatcgaac tattgactcc ctttaccaag gtagagttgg agccagaaat caaggagaaa
    39661 aaacgcaaac aagttgggat tttagggggg aattttaacc ctgttcacaa tgcccatctc
    39721 attgttgcgg atcaagtacg gcaacagttg ggactggatc aagttcttct catgcctgaa
    39781 taccaacctc ctcacgttga taaaaaggaa accatccctg aacaccatcg tctcaagatg
    39841 cttgagttgg caattgaggg gattgacggc ctagtcattg aaaccattga gttggagcgc
    39901 aagggtattt cctacaccta cgacaccatg aaaatcttga cagagcaaca tccagatacg
    39961 gattattact ttatcatcgg tgccgacatg gttgactatc tgcctaagtg gtaccgaatt
    40021 gatgaactgg ttgacatggt tcagtttgtg ggggttcagc gtccacgcta caaggcaggg
    40081 acttcctatc cagttatctg ggtggacgta ccgctcatgg atatctcgtc cagcatggtg
    40141 cgggacttca ttgcccaagg tcggaaaccc aactttctcc tacctcagcc agtgctagac
    40201 tacatcgaga aggaggggct ctactgatgt cctatcaaga ctatatcaac tgctcccgtg
    40261 aggccttgtt ggaaaaaatg gcagagcttc tacctgagaa acgtctaacc cattgtctag
    40321 gtgtggagcg tgccgctatg gagttagctc agcgctttgg tgtagatgtt gagaaagcaa
    40381 gtctagcagg tcttcttcat gactatgcta aaaagttgtc agatcaggaa tttctagact
    40441 tgattgaccg ttatcagcta gatttcgacc tcaaaaactg gggtaataat gtctggcatg
    40501 gtatggtcgg aatttacaaa attcaggaag atttggattt gcatgattca gaaatcctgc
    40561 gagccattga agtccataca gtcggtgctg gtcaaatgac agacctagat aaggtcatct
    40621 acgtcgcaga ctatatcgag cacaatcgag cctttcctgg agtagatgtg gcgcgtgaga
    40681 ttgcaagtct atcgctcaat aaggcggtgg cctacgaaac agctcgtacc gtggagtatc
    40741 tagctcatca gggattcccc atctatcccc aaacccttga aacctataac gcctttgtgc
    40801 actatttgaa agaggactaa atgaagacgg cttttataat cattgatgtt cagaatgttt
    40861 tagtagaaac tgggttccag acaaaaagtc tattggaaaa aatttcttat ttacaaaacc
    40921 aggctagaag caagaatatt gaaattatct atgttcaaca tattgagaat tctgaagctc
    40981 aaacatcaga agattggcag ttatctgcgc ttttaaatcg aaaacctgct gaaaaggtct
    41041 ttcagaagaa gtataacagt attttcaaag aaactggctt aaaagaatac ttggataaac
    41101 aggggattga aaaattagtt ttatgtggta tgcagacaga atattgtgtg gatacctctg
    41161 tcaaggttgc ctttgaatat ggctatcagc ttattgttcc agaaggtgct gtcacaacct
    41221 ttgatgggga tgacattcca gcagaaacga ttaatgaatt ttatgaggac atttgggagg
    41281 agtgctttgc agatgttcta gattacaaac atattttcta aaaagaggat taaatgaacg
    41341 aaaaagaatt actagaacta gtcgtgaaag cggctgatga gaaacgtgcg gaggatatcc
    41401 tcgcacttga tgtacaagat ttgactagtg tgacggacta ctttgtcatc actagctcaa
    41461 tgaatagccg tcagttggac gctatcgcag ctaatatccg tgaaaaagta gctcaagcag
    41521 gctttaaagg tagccatatc gaaggcgatg cagctggagg ctgggtctta ctggacctcg
    41581 gtgctgttgt cgtgcatatc ttttcagaag aaatgcgtgc ccattataat ctagagaagc
    41641 tatggcatga ggcgaattca gtagatattt cagaagctct tgcttagaag atgaactcag
    41701 ttgtagtcaa ctgggtttct ttgcttattt tagaaaaatt gatagaaagg taaagggcta
    41761 gtggtgttta ccatggagct cttagtatca tgattatggc gacttatgaa acctttgcgg
    41821 cggtctatga tgcggtcatg gacgatagtt tatacgacaa atggacgaat ttttctctgc
    41881 gtcatttgcc taagaccaag gagagaaaga aactcttgga attggcttgt gggacaggaa
    41941 ttcaatcagt gcgcttctct caggctggtt ttgatgtgac tggacttgac ttgagtgcgg
    42001 atatgttgaa gattgcggag aagagagcaa cttcagccaa gcaaaagatt gcttttatag
    42061 aaggtaatat gctgaatttg tccaaggcag ggaaatacga ttttgtcacg tgttattcgg
    42121 actctatctg ctatatgcag gatgaggtgg aagtagggga cgtctttaag gacgtgtaca
    42181 atgcgctgaa tgaagaggga gttttcatct ttgacgtgca ctcgacctac cagacagatg
    42241 aagtattccc tggctattcc taccatgaaa atgcggaaga ttttgccatg ctttgggata
    42301 catatgagga cgaagttcct cactccatcg tccatgagct gactttcttt atcaaggagg
    42361 ctgatggttc ctttagtcgc cacgatgaag tacatgagga gaggacctat gagatcttga
    42421 cctatgagat cttgctggaa caggctggat tcaagtcctt caaactctat gcagactttg
    42481 aggataagga gccaacagaa actagcaccc gttggttttt tgtggcgcag aagtaggaga
    42541 ttagcatgac cataacaggt attatcgcgg agttcaatcc ttttcataat ggccataaat
    42601 acctgctgga tcaggcagag ggactgaaaa ttgttgccat gtcagggaat ttcatgcagc
    42661 gtggagagcc tgctattgtg gataagtgga caagggccca gatggcgctg gaaaatggcg
    42721 cagacttggt agtggaattg ccctttttag tcagtgttca ggcagctgat ttctttggtc
    42781 aaggagctgt ggatatcttg gatcgcttgg gcattgatag tctagttttt gggacagagg
    42841 aagttctgga ttaccagaaa atcgctgact tatacacaga gaaaggtgct gagatggaga
    42901 aatttgtgaa aaatctgcct gattcccttt cctatcccca gaaaacccaa gctatgtgga
    42961 aggaatttgc tggtcttgat ttttcaggta atacccccaa tcatgttctt gctctggcct
    43021 atgcaaaggc ggttgcagga cgaaatatca agctgcatcc gattcagcgt cagggggcag
    43081 gttaccattc tgtgaataaa gatgtggact ttgcctcggc gacagccctc cgtcaacatc
    43141 agaaggacca agatttctta gaacgtttta tgccttctgt tgccctattt gagcaggcca
    43201 gtaaggtgat ctgggaagac tattttccct tgctccgcta tcaaatcttg tcaaatcccg
    43261 acctaaccac catctatcag gtcaatcaag aaatggctgt gcgcattaaa gaagctatta
    43321 aaacagccca gtctgtggaa gaattggtcg agttagtgac taccaaacgt tacaccaagg
    43381 cgcgtgtcag acgcctattg acctatattt tggtacaggc tagagaaaat gtcttgccag
    43441 aagccattca tgtccttgga tttactgaaa aaggcaggca acatctcaag tctctgaaag
    43501 gacaggtcaa tctagtcagc cgaattggca aagaaccttg ggatgctatg actcaaaagg
    43561 ttgaccagat ttaccaacta ggaaagccaa gtatagcaga gcaaaatttt ggcagagtgc
    43621 cgattagaat agaaacaaac taagtctact gaaaggtagg cttttttatt gtagaaattt
    43681 tagataacaa attgaagata aagtttttgg aaaatgataa actccctaat acagaagaca
    43741 aaaagtcaat aaagaaaatt agtatatgaa ccttaatctt tatctttgaa tccgctttat
    43801 gcttgttatt ttgtggtata atgaagagaa ctggttatat taataatcat aaattgaata
    43861 taaaagacaa ataaattttt atatttataa accatgataa acttttgttt aagattatgt
    43921 aataaaaaag aagatttata aggataattt gtatttatgt agtacaagct aatgtaggat
    43981 agttaaaata tggaagaaaa ttataattta tctataactc aaataaagaa ttctattaaa
    44041 gaaaattcct tagttttgtt tgttggtgca ggaatatcag ctaattctaa tctaccaact
    44101 tggggagaat tgattcaatc attaaaaaaa gaattgaaca taccagaaga aagaacagat
    44161 agtccactga gaattgctca gtattattat gatacttttg ggaaaaatca gtacacaaag
    44221 aagatagaag aaattttctt taagaaggga ttgagtaaac caaatgagtt acataaatta
    44281 atagaaaaaa ttgcaccaaa acatattatt acgacaaact atgattcact tctggagagt
    44341 caatttgaaa gtggcttgtt aaagtacaat gtagtcgctg aggataaaga catcccttat
    44401 acgagttcgg aaagatactt gattaaaatg catggtgact tcagtaagaa aaatattgtt
    44461 ttgaaagaag atgattattt agactatcat ttgaacttcc caatgatttc tactttaatc
    44521 cagtcattga taatgaatca tactctattg tttgtggggt attctctaag tgattcgact
    44581 tttaattcaa tttttagaat gattcaaaat acatttaaat tggatgctaa aaatgcttat
    44641 ttttatactc ccgaggaacc gtctatgatc attcgagagt attataagaa gcaaggaatt
    44701 ttcattatct ctaatgaaga gaatctaggt caggagacat cagaaaaaca gaacaaattg
    44761 tattgcagga caaaagattt tttagaggtt ctatcagaaa accgaagtca agatgtaaat
    44821 aatgctgatg atttatggaa tcaactggct tttttagata gacttagttt tattgatgcg
    44881 aaagattttt ctagatattc tgatttaaag aaaagggctt taaactggga tgatgagtat
    44941 tgctggtttg gaaatgatca attaagattt gaaattgatg gtcatgaaga attacgaatt
    45001 atggtatcta aaaaatcttt attaaatcgc tttctagata tggagattgg tgagcctagg
    45061 gatttaaagg ggaatcgatt cttaagtaag gcttttaagt tgtatgaaga aaaacaatat
    45121 tctttagcaa aagcaaaatt tagagaacta gctaatatag catttcgtca gaaagactat
    45181 tttaatttct tagtttgtga atttaatttt cagcaaattc aaataattga tagatacgaa
    45241 aaaacaccta gttatgcaga gccactttat gatggagaat taagcgaatt aacagaacaa
    45301 attcttaact cggttacagg agatgagaaa aagattatag aattttttag agattcaatc
    45361 cttaacttca attttttata tagaaaatta gaaactatta atgaattatt tgatgaaatt
    45421 cgtgaagagc atgaaagcta tagaagagga ggatggtctg ctaataatca tctatttaat
    45481 gcggagttta cagtaaaaaa tctttataac tttttaaaat taaattgttt atgtgttgaa
    45541 cattataaga tttataaatc aatcattaat agatatttag aaatattatt actcagttat
    45601 gataattcat atgtaaaccc tgactcaagt attttcgata gaacatcttc ttggcttaaa
    45661 aatcttgatt tggatgatgt taaattaatt cttccgaata tagattttaa ggttgtaaat
    45721 ttatatttta gaaactattc atttggtaaa ataaaagtta ctgaggaagc gaaagactac
    45781 ttgttgaatc gaattactta tcttcaagaa agacttgaaa ttactgaaga tgaaaatctt
    45841 cgagagctta aaaatatgct aatttttctt ccccttgttg atgatattga catagaaaaa
    45901 gtaatagaaa ttttaaataa tcaaacactg tattataatt ggagcgagga atttaggaga
    45961 attattaaaa ttgtcctcga taatatggat gttattgata aagattcatt gaaatctaag
    46021 ataattggga ttgtaaataa acatttaaat gaaattttgg agaaaaattt ttctttatat
    46081 aattcagtgt atccgctcta ttcacagtta ctagaatact gctcaactga tcaggaaact
    46141 gcaataatag tactcgaaaa atttaataca gatattttaa gaataaaata taaaaatgat
    46201 gatataaaaa atatcataga atattctgac ttgatatgtc acttatttaa gtattttgaa
    46261 aaggatatta aagatgacat tttagatact ctaaaagttt atgaagaatc agaaaatatt
    46321 atttaccata aagtaattga tttgatgagt tataatgtct atgattttcc tcagatacaa
    46381 aataaaatct accattattt gattaaaaga attaatgata aaagagttga gggggttaaa
    46441 actttcccag acccaagaga aaagtctgta tcagatttat acaacttaag tagaaaagga
    46501 tatttttctg attttgagat tttaaaagat attgaagaag atattcgagg actttatcct
    46561 gaagtagatt ggacctggtt ccatgataga agtgatgatg ttatccatcg tctactagaa
    46621 catagaactc ccaataatat taaaacttat ttttcaaaaa atgaagaaga taataaattg
    46681 attaatgagt atattttaaa agctttcgat gaggataaat taatacttaa gaaataaatt
    46741 gatacaacta aataaaaaag ttaatttatg acaaatttga tcttgaagat aagctgtgat
    46801 ttcctaaagt gaattttcaa agacttgaaa gcaaaatgtt tgaatctagt ggaacactat
    46861 ttggcacaac aatagaaaat ccatagcggt agaaattcgg tggaactttt tgatagcggc
    46921 actgacttat ctccttaaaa aaccaaggaa gtgtaatcct aaaattcaga ctaatttccc
    46981 caaaacatat tctattttag gtttgtgaaa atcacttttt tatggtagaa tgtaaaagaa
    47041 tgtatgtcat tcggaataac aataaaatga ggtaaaaaca tggagatcat gtcgcttgcg
    47101 attgctgttt ttgccgtcat cattggttta gtcattggat atgtcagcat ctcagctaag
    47161 atgaaatcat ctcaggaagc tgcggagttg atgcttttaa atgctgaaca agaagcaact
    47221 aatttacgtg gacaagctga gcgtgaagcg gatttacttg ttaatgaagc taaacgtgaa
    47281 agcaagtctc ttaaaaaaga agcactattg gaggccaaag aagaagccag aaaataccgt
    47341 gaagaagtgg acgctgaatt caaatcagaa cgtcaagaac tcaaacaaat cgaaagtcgt
    47401 ttgacagaga gagctactag ccttgaccgt aaggacgaca atttgacgag taaagaacaa
    47461 acacttgaac aaaaagaaca aagtatttct gatagagcga aaaaccttga tgcgcgtgaa
    47521 gagcaattag aggaagtcga aagacaaaaa gaagcagaac tagagcgtat tggtgctctg
    47581 tctcaggcag aagcacgaga tattatcttg gctcagacag aggaaaactt gaccagggag
    47641 attgccagtc gcattcgcga agctgagcaa gaggtcaagg aacgttctga caaaatggcc
    47701 aaggatatct tggttcaagc tatgcaacgt atcgctggtg aatatgtagc ggagtcaaca
    47761 aactcaacag ttcatctgcc agacgatact atgaagggac gcattattgg tcgtgaaggt
    47821 cgtaacattc gtacctttga aagtttgaca ggggtcgatg tgattatcga cgatacacca
    47881 gaagtggtga ccttgtcagg atttgatccg attcgtcgtg agattgcccg tatgactatg
    47941 gaaatgttgc tcaaagatgg tcgtatacat ccagctcgta tcgaagagtt ggttgagaaa
    48001 aaccgtcaag agattgacaa taagattcgt gaatacggtg aggctgctgc ctatgaaatt
    48061 ggtgcgccaa accttcatcc agacttgatg aagattatgg gacgtttgca gttccgtact
    48121 tcatatggac aaaatgtttt gcgccattcg attgaggttg ctaagttggc tggtatcatg
    48181 gcgagcgaac ttggtgaaaa tgcggctctt gcccgtcgtg ctggattcct tcacgatatc
    48241 gggaaagcca ttgaccatga ggttgaaggt agccacgttg aaatcggtat ggaattggcc
    48301 cgtaagtaca aggaaccccc agttgtggtg aatacgattg ctagtcacca cggagatgtt
    48361 gaagctgaga gcgtgatagc agttatcgtc gctgcagcag atgccttgag cgcagcccgt
    48421 ccaggtgctc gtagtgagtc tcttgaaagc tacatcaagc gtctccatga tttggaagaa
    48481 attgctaacg gctttgaagg agtgcaaact agctttgccc ttcaagcagg acgtgaaatt
    48541 cgtatcatgg tcaatccagg aaaaatcaag gacgacaaag tcacaatctt ggctcacaaa
    48601 gttcgtaaga aaattgaaaa caatctcgat tatccaggaa atatcaaggt aaccgtgatt
    48661 cgcgagcttc gtgcagtaga ttatgctaaa taaataagaa agagcagttg aaaaattact
    48721 gcttttttgt tacactagat agaaagactg taaaggataa tctggctttt tgccattatt
    48781 ctagagaaat gttatttcac agattgacta aaaggagaca caatggcaga ccgaggctta
    48841 ctaatcgttt tttctggtcc ttcaggggtt ggaaaaggaa cggttagaag agagattttt
    48901 gagagttctg aaaaccaatt tcaatattct gtatcgatga cgacacgcgc acaacgtcct
    48961 ggagaagtgg acggtgttga ctatttcttc cgtactcgtg aagaatttga agagctgatt
    49021 cgtcaaggac agatgttgga atacgcagaa tatgtcggca actactatgg aactcctctg
    49081 acctatgtca atgaaacctt ggacaaggga atcgatgttt tccttgaaat tgaagttcag
    49141 ggtgctcttc aggtcaagaa aaaggttcca gatgctgtct ttatcttcct gacaccacca
    49201 gatttggatg aattgcaaga tcgcttggta ggtcgtggaa cagatagtgc agaagtgatt
    49261 gcccaacgaa tcgaaaaggc caaggaagaa attgccctca tgcgtgagta tgattatgcg
    49321 attgtcaacg atcaggtgcc cctagctgct gaacgtgtca aatgtgtgat tgaagcagaa
    49381 cacttctgtg tggatcgtgt cattggtcac tatcaggaga tgttaccaaa atctccaact
    49441 acccgataaa atttagaaaa taggtacaag caaatgatgt taaaaccctc tattgatacc
    49501 ttgctcgaca aggttccttc aaaatattca ctcgtaatct tggaagcaaa acgtgcccac
    49561 gaattggaag caggtgcccc agcaactcaa ggtttcaagt ctgaaaaatc aactcttcgc
    49621 gctttagaag aaatcgaatc aggaaacgtt acaattcacc cagatccaga aggaaaacgt
    49681 gaagcagtgc gtcgccgtat cgaagaagag aaacgccgca aagaagaaga agaaaagaaa
    49741 atcaaagagc aaattgctaa agaaaaagaa gatggtgaaa aaatttaagg ttggggggac
    49801 tcaatcttat tttttctatt gcaagaatgt actgacaagg aggaggtgag aagatggccc
    49861 tagctaagat tatcgtagat gtgcctttga tgcagacgga ccagccctat agttacagga
    49921 ttccggagga atttgaggga atgctggaag ttgggatgcg ggttcatgta ccttttggta
    49981 agggtaatcg cctgattcaa gggattgttc ttggtttgga gtcccaatca gatggagaag
    50041 agatggagca agatttaaaa gatattgcag aggtgctgga tttttctcct gttctcacgc
    50101 cagaacaact ctggctggct gaggagttac gcaaatctgt cttctcctac aaaatctcta
    50161 tcctcaagac catgcttcca ggatttctga attctagcta tgacaagatt ctctatcctc
    50221 tggaaggctt gagtcaggaa gaacgagtac gcctgtttgg ttcagaagat tcgctagcct
    50281 tttcttcact agaccttgcc aagcaagctg aaatgatgcg tttgactaga aaaggcctgc
    50341 ttggtctgga atatcaggca gtcgatcaaa agaaggtcaa gacccagtct tggtatgagg
    50401 ttgaccatgc ccaattagaa ggtgttgaga tttctacacg tgccaagaaa aagttggaac
    50461 tgagagatta tctgctgtct catccagaga gcgcttcctt ggctagcttg ttagagtcct
    50521 actcgcgaga gcaagtcaac ttctttgtgg atcaaggtgc tgttaccata gtccaaaagg
    50581 aagttcaacg ctcggctgct tattttgaag gaattgaagc aagtagacct ttggagttaa
    50641 atccagaaca aagacaggcg cgtgatgcgg ttgtgagttc tattggcagt tctcaacctc
    50701 cctttctact tcaagggatt acaggaagtg ggaagaccga ggtttacttg cagattatcc
    50761 aaggtgccct ggataagggc aagacagcta ttttgctggt acctgagatt tccttgactc
    50821 ctcagatgac cgagcgtttt atagcacgtt ttggggacaa ggtagccatt cttcactcag
    50881 gattatccaa tggtgaaaag tatgatgaat ggcgcaaggt ggagcgtggc gatgcccaag
    50941 ttgttgttgg tgccagatct gctatctttg ctcctctgaa aaatctgggt gtcatgatta
    51001 ttgatgaaga gcatgaagcg gcttataagc aggacagcaa tccccgttac catgccagag
    51061 aggtagctat tttacgggct cagtataatc aagcaactct ggtacttgga tctgcaacgc
    51121 cgagcttaga gagccgggca cgtgctggca aaggcgtcta tcaacactta cgtctaaccc
    51181 aacgtgccaa tcctttggct acaatccctg aggttcaagt gattgacttt cgagactata
    51241 tcggacaaaa tgagacgtca aactttacgc ctcctttgct agaggctatc caagaccgtc
    51301 tggttaaaaa agagcaggtg gttctcatgc tcaatcgccg tggttattct agctttgtca
    51361 tgtgtcggga gtgtgggacg gtggatactt gtcccaactg cgatatttct ctgaccttgc
    51421 atatggatac caagactatg aactgccatt attgtggttt ctcgaaggat attcctcagg
    51481 tctgtcctaa ctgtaagagc cacagtattc gttactatgg gacgggaact cagaaggctt
    51541 atgatgagct agcagaactc tttccccaag ctcgcatttt taggatggat gtggatacga
    51601 ctcgaaagaa aggcagtcac caagccttgc ttgaccagtt tgggcgaggg gaagcggata
    51661 ttttacttgg tactcagatg attgcaaagg gtttggattt tcccaatgtt accctagtcg
    51721 gagttctaaa tgcggatacg gccttgaatc tgcctgattt ccgttcttct gagagaacct
    51781 tccagctctt gactcaggta gcaggtcgag caggtcgggc tgaaaaagca ggtcaagtct
    51841 tgatacagtc ctacaattcg cagcactatg ctattcgatt tgccaaggat caagattacg
    51901 aaggctttta tgcctatgaa atgggaatca gacgacaact cggctatcca ccttactatt
    51961 tcacgattgg tattaccctt tctcacaaga aagaagaaga ggttttcaaa cgtgcctatg
    52021 aagtcatgaa cattttgcgg tcaggcttgt cagagaccag tcccattctg gggccaacgc
    52081 caaaaccgat tgcccgtacc cacaacctct atcattacca gattttaatt aaataccgtt
    52141 tagaagatga gctggggccg accctcaacc aggtcttggc cttgactcaa gaacgggaaa
    52201 atagtgagct ccgtctcagc attgaccatg agccgcagca atttttataa gaaggagaag
    52261 atatgacaaa actaatcttt atggggaccc ccgacttttc agcaacagtc ttaaaaggac
    52321 ttttgacaga tgaccgttac gaaattctag ccgttgtgac ccagccagac cgtgctgttg
    52381 gtcgtaaaaa agttatccaa gaaaccccag tcaagcaggc tgccaaggaa gcaggactat
    52441 ctatctacca acctgaaaaa ttatctggaa gtccagagat ggaagaactt atgaagctag
    52501 gagcagatgg aattgtgact gctgcttttg ggcagtttct cccaagcaaa ctccttgata
    52561 gcatggactt tgctgtcaac gttcatgcct ccctccttcc tagacaccgt ggtggtgcgc
    52621 ctatccatta tgccttgatt caaggggatg aggaagctgg tgtgaccatc atggaaatgg
    52681 ttaaggaaat ggatgcagga gatatgattt ctcgtcgcag cattccgatc acagatgagg
    52741 acaatgttgg caccttgttt gaaaaattgg cgctagttgg tcgtgatttg cttttggaca
    52801 ctctgcctgc ctatattgct ggtgatatca aacctgaacc gcaggatacg agtcaggtta
    52861 ccttctctcc aaatataaag ccagaggaag aaaaactgga ctggaacaaa accaatcgtc
    52921 aactctttaa ccaaattcgt ggaatgaacc cctggcctgt tgcccatact ttccttaagg
    52981 gcgaccgctt taagatttat gaagccctac cagtagaagg tcagggaaat ccaggtgaga
    53041 ttctctctat cggcaagaaa gaattgattg tcgcaacggc tgaaggggct ctatccctca
    53101 aacaagtgca gccagctggt aagcctaaga tggacattgc ttccttcctc aacggagttg
    53161 gacgtacatt gactgtagga gaacgatttg gtgactaaag tagaaacggc tagaagttta
    53221 gctctagcag tgctagagga tgtttttgtg aaccaagcat attcaaatat cgccttaaat
    53281 aaacacctca aggggagtca gctctctgca gcagacaagg gcttagtgac cgagctagtc
    53341 tatggaacgg tagcccgtaa actgactctg gaatggtacc tatcccactt tatcgaagac
    53401 agagaccagt tagacagctg gctctatgtc cttcttctca tgagtgtcta ccaactccgc
    53461 tatttggaca agattccaga tcatgctgtg gtcaatgaag cagtggaatt ggccaaactc
    53521 cgtaaaaaag gcagtgaaaa attggtcaac gctgtccttc gccgtatctt gcgtgaaggc
    53581 tggccagata ttgctaacat caagcgaaaa aacaagcgtg actccattgc ctattctctc
    53641 ccagtttggc tagttaccaa actcaaggaa gaatacggag aggagagagc aaaagccatc
    53701 tttgaaagct tgttagtgcg aaacaaagct agtattcgtg taacagacct aagtcgaaaa
    53761 gaggaaatcc aagccttgtt ggaggcgaat agttcccttt tagcaaccac tggtctggtt
    53821 aaggagcaag ggcattttgc agggcataat ttgtttgcgg atggagccat taccatccaa
    53881 gatgagtcca gtcagctggt tgctccgacg cttgatttac aaggtgatga gcgagtgctt
    53941 gatgcctgtg cggctccagg tgggaaaaca gcccatatag cctcttatct tacgacaggt
    54001 caggttactg ctctggactt gtacgaccac aagttggatt taattcaaga aaatgcccaa
    54061 cgtctgggag ttgaagatcg ggttcaaact caaaaattgg atgccagaaa ggtgcatgag
    54121 ttttttgacc aggattcctt tgataagatt ttggtggatg ctccttgttc aggaatcggt
    54181 cttttgcgcc gaaaaccaga tatcaaatac aataaagaaa cggcagattt cgcgtccttg
    54241 caggaaattc agttagaaat attaggtagt gtttgtcaaa tactaggcaa aggtggtata
    54301 ataacttata gcacctgcac tatcgtctca gaggagaatt ttcaagtcgt taaggccttt
    54361 ttagagagtc atcccgagtt cgagcaggta aaactagaac atgaatgtaa ggatatcatg
    54421 aaagacggct gtatcctcat tacacctgaa ttgtatggaa gtgatggatt cttcatcagt
    54481 caatttcgca agatatcgga ttaggaagga actgacacat ggaaatttca ttattaacag
    54541 atgttggtca gaaacgaaca aataaccaag actatgtcaa ccactatgtc aatagagctg
    54601 gacgtaccat gattatttta gctgatggga tgggaggtca tcgtgcaggg aatatcgcta
    54661 gtgaaatggc ggtcacagac ctgggtgtag cttgggttga tacccagatc gatacagtca
    54721 atgaagtgcg tgaatggttc gcccattacc tagaaattga aaatcaaaag attcaccagc
    54781 ttggtcagga tgaagcttac agaggcatgg gaactacttt ggaagtcctt gctattattg
    54841 ataatcaggc tatctatgct catattggtg attcgcgtat cggcttgatt cgtggagaag
    54901 aataccatca gttgacgagc gatcattcct tggttaatga attgctcaag gctggtcaat
    54961 tgacaccaga agaggcagaa gctcatccgc aaaaaaatat tatcacccag tctattgggc
    55021 aaaaagatga aattcagcct gattttggga cagttatcct tgagtcaggt gactatctct
    55081 tgctcaatag tgacggcttg accaacatga tttcaggcag tgagattcgt gatattgtaa
    55141 ccagtgatat tcctttagca gataaaacgg agacacttgt tcgttttgct aacaatgcag
    55201 gaggtttaga caacattacg gttgcccttg tttctatgaa cgaggaggat gcagaatgat
    55261 ccaaatcggc aagatttttg ccggacgcta tcggattgtc aaacagattg gtcgaggagg
    55321 tatggcggat gtctacctag ccaaagactt aatcttagat ggggaagaag tggcagtgaa
    55381 ggttctgagg accaactacc agacggaccc gatagctgta gctcgttttc agcgtgaagc
    55441 gagagctatg gcagatctag accatcctca tatcgttcgg ataacagata ttggtgagga
    55501 agacggtcaa cagtatcttg caatggagta tgttgctgga ctagacctca aacgctatat
    55561 caaggaacat tatcctcttt ctaatgaaga agcagtccgt atcatgggac aaattctctt
    55621 ggctatgcgc ttggcccata ctcgaggaat tgttcacagg gacttgaaac ctcaaaatat
    55681 ccttttgaca ccagatggga cggccaaggt cacagacttt gggattgctg tagcctttgc
    55741 agagacaagt ctgacccaga ctaactcgat gttgggctca gttcattact tgtcaccaga
    55801 gcaggcgcgt ggttcgaagg cgactgtgca gagtgatatc tatgccatgg ggattatttt
    55861 ctatgagatg ttgacaggcc atatccctta tgacggggat agcgcggtga ccattgccct
    55921 ccagcatttc cagaaacccc tgccgtccgt tattgcagaa aatccatctg tacctcaggc
    55981 tttagaaaat gttattatca aggcaactgc taaaaagttg accaatcgct accgctcggt
    56041 ttcagagatg tatgtggact tgtctagtag cttgtcctac aatcgtagaa atgaaagtaa
    56101 gttaatcttt gatgaaacga gcaaggcaga taccaagacc ttgccgaagg tttctcagag
    56161 taccttgaca tctattccta aggttcaagc gcagacagaa cacaaatcaa tcaaaaaccc
    56221 aagccaggct gtgacagagg aaacttacca accacaagca ccgaaaaaac atagatttaa
    56281 gatgcgttac ctgattttgt tggccagcct tgtattggtg gcagcttctc ttatttggat
    56341 actatccaga actcctgcaa ccattgccat tccagatgtg gcaggtcaga cagttgcaga
    56401 ggccaaggca acgctcaaaa aagccaattt tgagattggt gaggagaaga cagaggctag
    56461 tgaaaaggtg gaagaagggc ggattatccg tacagatcct ggcgctggaa ctggtcgaaa
    56521 agaaggaacg aaaatcaatc tggttgtctc atcaggcaaa caatccttcc aaattagtaa
    56581 ttatgtcggc cggaaatctt ctgatgttat cgcggaatta aaagagaaaa aagttccaga
    56641 taatttgatt aaaattgagg aagaagagtc gaatgagagt gaggctggaa cggtcctgaa
    56701 gcaaagtcta ccagaaggta cgacctatga cttgagcaag gcaactcaaa ttgttttgac
    56761 agtagctaaa aaagctacga cgattcaatt agggaactat attggacgga actctacaga
    56821 agtaatctca gaactcaagc agaagaaggt tcctgagaat ttgattaaga tagaggaaga
    56881 agagtccagc gaaagcgaac caggaacgat tatgaaacaa agtccaggtg ccggaacgac
    56941 ttatgatgtg agtaaaccta ctcaaattgt cttgacagta gctaaaaaag ttacaagtgt
    57001 tgccatgccg agttacattg gttccagctt ggagtttact aagaacaatt tgattcaaat
    57061 tgttgggatt aaggaagcta atatagaagt tgtagaagtg acgacagcgc ctgcaggtag
    57121 tgcagaaggc atggttgttg aacaaagtcc tagagcaggt gaaaaggtag acctcaataa
    57181 gactagagtc aagatttcaa tctacaaacc taaaacaact tcagctactc cttaaaagta
    57241 gatggataat caaaatgagt aatcaatctt tgtcatgatt tcatggcaaa gatttttttt
    57301 gagtccagat ttgtgataga atagagggag ttgataaaag gaggaaagca tggaagaatc
    57361 aaaagaatta aatgccgtca ttgatgtgat tatgctagcg gggactattc tccttaaaag
    57421 tggctcagaa atccatcgtg tagaagatac catgattcga atcgcgcatt cgcaggggat
    57481 tgtggattgc aatgtccttg ccatgcctgc cgctatcttt ttctctattg aaaataccaa
    57541 tatttcgcgc atgaagcgcg tgacctcctc ttcttataac atcgaaaaag tctgcgatgt
    57601 gaaccagatt tctcgtcagc tggttggggg gcagattgat ttagaaacag cctttaagca
    57661 attgacggcc ttgcaagctc aaccccttcc ctatactaag ttgcaggtaa ctctggctgc
    57721 gacctttagt gctcctttct tttcagttat gtttagcgga aatatctacg acgcacttgg
    57781 ggcaggagtg gcgaccttat ttggttttgc cttttccctc tatgtggaaa aatttatccg
    57841 aattcccttt gtgacagcct ttgctggagc ctttgtcttt gggataattg cccagttttg
    57901 ggctcgctac acaggttttc cttcaacggc agatttgatt atagctggtg cggtcatgcc
    57961 gtttgtacca ggtattgcct tgaccaatgc ggtccgtgat attatgacca accacataaa
    58021 ctctggtatg agtaagatgt ttgaatccct gctcattacc ctcgctttag gggcaggaac
    58081 ttctgtcgcc ttggtattgg tgaactaata tgacactaac aaccttttta ttacaagcag
    58141 tagcaagttt tcttgccatt atcacttttt taatcgtact caatgtgcaa cggtctatgc
    58201 tcttacctgg agggattttg ggcatgactg tctggctaat ctatctcttg ctcaaggaac
    58261 cgaccaatgt cattgtagct accttcattg cagccattat tggttcttgt gtcagccaga
    58321 ttttaagtat tctttataag acacctgctg tggtctttat cttggccatt ttggcaccgc
    58381 tggttccagg ttatctctcc taccgaacaa ctgccttttt tgtgacaggg gactataata
    58441 aagcactggc aagtgcgacc ttggttgtca tgttggcttt ggtaatctct attggaatgg
    58501 ctagcggaac agtgattctc agactgtatc attatataaa aacacatcga gtatcgtaga
    58561 ttttacagaa ataaaagaat tttctgaaaa atgagataaa taaattaaca acgctttcta
    58621 tatgtgcgag aatatcgaac ttatgaagaa attgcggctg attttggtat ccacgaaagc
    58681 aacttactcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg ttttacgatt
    58741 tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgga agtaaaaatc
    58801 aatcgcccta aaaaaagaat tagcgaatta ttctggtaaa aagaaatgcc acgctatgaa
    58861 ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatca ctgtgaacta
    58921 ttgtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag ctggtaaaat
    58981 cttggctgac agtgattatc aagggctcat gaagatatat cctcaagcac aaattccacg
    59041 taaatccagc aaactcaagc cgct
//
LOCUS       DAVBOU010000009        56019 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBOU010000009 DAVBOU010000000
VERSION     DAVBOU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.009"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ879_000539"
     CDS             complement(141..1010)
                     /locus_tag="VQ879_000539"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3142750.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ879_000540"
     CDS             complement(1012..2298)
                     /locus_tag="VQ879_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3142751.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ879_000541"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ879_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3142752.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ879_000542"
     CDS             complement(3386..4420)
                     /locus_tag="VQ879_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3142753.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ879_000543"
     CDS             complement(4449..5882)
                     /locus_tag="VQ879_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3142754.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ879_000544"
     CDS             complement(5898..6884)
                     /locus_tag="VQ879_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3142755.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ879_000545"
     CDS             complement(6886..7989)
                     /locus_tag="VQ879_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3142756.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ879_000546"
     CDS             complement(7979..8824)
                     /locus_tag="VQ879_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3142757.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ879_000547"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ879_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3142758.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ879_000548"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ879_000548"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3142759.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ879_000549"
     CDS             complement(11219..11695)
                     /locus_tag="VQ879_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3142760.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ879_000550"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ879_000550"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3142761.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ879_000551"
     CDS             complement(13063..13401)
                     /locus_tag="VQ879_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3142762.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ879_000552"
     CDS             complement(13412..14515)
                     /locus_tag="VQ879_000552"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3142763.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ879_000553"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ879_000553"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3142764.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ879_000554"
     CDS             complement(15701..16768)
                     /locus_tag="VQ879_000554"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3142765.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ879_000555"
     CDS             complement(16787..17641)
                     /locus_tag="VQ879_000555"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3142766.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ879_000556"
     CDS             complement(17631..18308)
                     /locus_tag="VQ879_000556"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3142767.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ879_000557"
     CDS             complement(18305..19468)
                     /locus_tag="VQ879_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3142768.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ879_000558"
     CDS             complement(20155..21789)
                     /locus_tag="VQ879_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142769.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ879_000559"
     CDS             complement(21770..22519)
                     /locus_tag="VQ879_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142770.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ879_000560"
     CDS             22698..24152
                     /locus_tag="VQ879_000560"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3142771.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ879_000561"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ879_000561"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3142772.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ879_000562"
     CDS             complement(26881..27366)
                     /locus_tag="VQ879_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3142773.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ879_000563"
     CDS             complement(27641..27880)
                     /locus_tag="VQ879_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142774.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ879_000564"
     CDS             complement(28141..29211)
                     /locus_tag="VQ879_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3142775.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ879_000565"
     CDS             complement(29208..29981)
                     /locus_tag="VQ879_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142776.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ879_000566"
     CDS             complement(29978..30784)
                     /locus_tag="VQ879_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142777.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ879_000567"
     CDS             complement(30765..31922)
                     /locus_tag="VQ879_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142778.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ879_000568"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ879_000568"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3142779.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33851)
                     /locus_tag="VQ879_000569"
     CDS             complement(33099..33851)
                     /locus_tag="VQ879_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3142780.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ879_000570"
     CDS             complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ879_000570"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3142781.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34734..36005
                     /locus_tag="VQ879_000571"
     CDS             34734..36005
                     /locus_tag="VQ879_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3142782.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36025..36851)
                     /locus_tag="VQ879_000572"
                     /pseudo
     CDS             complement(36025..36851)
                     /locus_tag="VQ879_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ879_000573"
     CDS             complement(37008..37661)
                     /gene="phoU"
                     /locus_tag="VQ879_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3142783.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ879_000574"
     CDS             complement(37673..38431)
                     /gene="pstB"
                     /locus_tag="VQ879_000574"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3142784.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ879_000575"
     CDS             complement(38444..39247)
                     /gene="pstB"
                     /locus_tag="VQ879_000575"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3142785.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ879_000576"
     CDS             complement(39258..40142)
                     /gene="pstA"
                     /locus_tag="VQ879_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3142786.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ879_000577"
     CDS             complement(40132..41049)
                     /gene="pstC"
                     /locus_tag="VQ879_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3142787.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ879_000578"
     CDS             complement(41049..41927)
                     /gene="pstS"
                     /locus_tag="VQ879_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3142788.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42501..43805)
                     /locus_tag="VQ879_000579"
     CDS             complement(42501..43805)
                     /locus_tag="VQ879_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3142789.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43806..44579)
                     /locus_tag="VQ879_000580"
     CDS             complement(43806..44579)
                     /locus_tag="VQ879_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3142790.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44569..44847)
                     /locus_tag="VQ879_000581"
     CDS             complement(44569..44847)
                     /locus_tag="VQ879_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3142791.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44847..45248)
                     /locus_tag="VQ879_000582"
     CDS             complement(44847..45248)
                     /locus_tag="VQ879_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3142792.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45458..46075)
                     /locus_tag="VQ879_000583"
     CDS             complement(45458..46075)
                     /locus_tag="VQ879_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3142793.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46065..46838)
                     /locus_tag="VQ879_000584"
     CDS             complement(46065..46838)
                     /locus_tag="VQ879_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3142794.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46849..47586)
                     /locus_tag="VQ879_000585"
     CDS             complement(46849..47586)
                     /locus_tag="VQ879_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3142795.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47591..48721)
                     /locus_tag="VQ879_000586"
     CDS             complement(47591..48721)
                     /locus_tag="VQ879_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3142796.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     YGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48805..49194)
                     /locus_tag="VQ879_000587"
     CDS             complement(48805..49194)
                     /locus_tag="VQ879_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3142797.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49210..49593)
                     /locus_tag="VQ879_000588"
     CDS             complement(49210..49593)
                     /locus_tag="VQ879_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3142798.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49594..50382)
                     /locus_tag="VQ879_000589"
     CDS             complement(49594..50382)
                     /locus_tag="VQ879_000589"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3142799.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50375..51310)
                     /locus_tag="VQ879_000590"
     CDS             complement(50375..51310)
                     /locus_tag="VQ879_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3142800.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51440..51616)
                     /locus_tag="VQ879_000591"
     CDS             complement(51440..51616)
                     /locus_tag="VQ879_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3142801.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51756..52463)
                     /locus_tag="VQ879_000592"
     CDS             complement(51756..52463)
                     /locus_tag="VQ879_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3142802.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52614..53642
                     /gene="queA"
                     /locus_tag="VQ879_000593"
     CDS             52614..53642
                     /gene="queA"
                     /locus_tag="VQ879_000593"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3142803.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54303..54692)
                     /locus_tag="VQ879_000594"
     CDS             complement(54303..54692)
                     /locus_tag="VQ879_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3142804.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGLWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54746..55437)
                     /locus_tag="VQ879_000595"
                     /pseudo
     CDS             complement(54746..55437)
                     /locus_tag="VQ879_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
BASE COUNT        16658 a        12729 c        10401 g        16231 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagataac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca tttcctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc
    33541 aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat
    33601 gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata
    33661 ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa
    33721 gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt
    33781 ttggtaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata
    33841 tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca
    33901 ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca
    33961 actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag
    34021 gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc
    34081 tgaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata ttccggttga
    34141 tgggttgcga tatcagcaaa cttggtatcg ggtgttgact taggaatcat acgcacatgc
    34201 atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc atcataataa
    34261 gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc
    34321 tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga cacttccaca
    34381 atttctggct ggtctcctga ctctttggcc tgataagcct tgccatccaa gacaatcaat
    34441 tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag caattctcct
    34501 actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat
    34561 aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat
    34621 cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat
    34681 tgccaagaag gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    34741 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    34801 ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca
    34861 aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc
    34921 ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta
    34981 ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg
    35041 gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac
    35101 aatccattca caaactcctc tttgaccaag ctctctactg caaggctaac caactagtac
    35161 tgacttctgg aacccaacaa gccttgttta tcctctctca aatatccttt cctagccaag
    35221 ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac
    35281 aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg
    35341 aaggccactt caaaacagga aaaattaagt ttttctacac cattcctcga tttcactatc
    35401 ccctaggcca ttcctattct gagcaggaca aacgagctat tcttgactta gcagccaaat
    35461 atagtgttta tatcgtcgaa gacgactatc tgggggattt ggactctaaa aagggccaga
    35521 ccttccacta tctagataca gaggaacgcg tcatttatat caaatccttc tcaaccagcc
    35581 tctttccagc cttgcggata acagcactca ttcttccaaa tactatcaaa gaagccttcg
    35641 tggcctacaa aaatatccta gactacgaca gcaacctcat catgcaaaag gccctgtcac
    35701 tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat
    35761 cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc
    35821 ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac
    35881 acagtcaact gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat
    35941 ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg
    36001 aatgacatcc aactctgctt tttcttattc ttcaacttca gttaaacttg ctgctttttc
    36061 aagatagctt tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc
    36121 tttcaaatca tcactatttt ttctaagagc aacgacattg gcgtcgccgt ccttcatctt
    36181 caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg
    36241 ctcatccata tgaacagcat ctatttttcc agcctgcaat tcattgactg cttcacccat
    36301 attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac
    36361 agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc
    36421 cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc
    36481 aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc
    36541 agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt aagatttcca acttaacccc
    36601 aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc
    36661 atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt
    36721 ccccttttgc ttaatggcct caacagctga ctgagaacca ttagaacctg actggcaagc
    36781 tactaagaag aaacttgcaa gaaacttgca agaaaattac ataaaacaaa tatccatttt
    36841 tttgatttca taaataaaca acctttctgt taattttgta taattataac gatatccaag
    36901 ttacttgtca agtgtttttt aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg
    36961 agccatcagt tgatttcaag ctccttttta tacagaatta aactatttta tagttcgaca
    37021 atcttacctg tttcaaagta gacaacccat tcacagatat ttttagcata atcaccgata
    37081 cgctccaagt aggaaataac ttggaaataa tcacgacccg taacaatggc ttctggattt
    37141 ttcttaatct cttcagtcgc aaggtcacgg atagtttcaa aatagtggtt aatttgctca
    37201 tccatggagg ccacccggta tgcgtcgtca acagaaccat taagataaag atcaagtgct
    37261 gcttcaacaa cgcttttaac ttcacgtccc atttttttaa tttcttcctc tacagctggg
    37321 atgcgttctt cccccttcat acggatggtt gcctgggcaa tggctacagc gtgatccccc
    37381 atacgctcca catctgatac agccttaagg acagtcaaga ctgtacgcaa atcttgagag
    37441 actggttgtt ggagtgcgat catttcaaat gatttctttt ccagtttcac ttcgtattca
    37501 tttacttctg catcatcttc tatgacctct tttgccaggt cacggtcatg cgtgacaaaa
    37561 gcacgtaccg tacgattgat ttgtgagagc acttcttgtc ccatagcgta gaactggtta
    37621 tgtaatttct ctaaatcttc ttcaaattga gatcgtaaca tctttcatct ccttatccaa
    37681 attttcctgt aatatagtct tccgtttcct tgtgttgggg atcaaggaac atctgcttgg
    37741 tatcattaaa ttcaatcaaa tctccatcta ggaaaaatcc tgtcttatca gagatacgtg
    37801 aagcttgctg catggaacgg gttaccagaa gcatggtgta cttgtctttt agaccataca
    37861 aggtttcctc aattttacca gctgaaatcg gatccaaagc cgaagttggc tcatccaaga
    37921 ggatgatttt aggactagtt gccaagacac gggccacgca gacacgctgc tgttgaccac
    37981 ctgacaatcc aatagctgaa tcatatagac gatccttgac ctcatcccag atagaggcac
    38041 cttgcaaggc tttttctacg gcttcatcca gaacctgctt atccttaatt ccattgatac
    38101 gaagcccgta gacaacattc tcatagatag tcatagggaa aggattaggt tgttggaaaa
    38161 ccattccgat ttccttacgt aattcaaccg tatctgtacg cggactgtag atgttgtgac
    38221 cattgtacac cacggatcca gttgtggtca cctctggatt gagatctccc atgcggttga
    38281 gagacttgag gagggttgac ttccctgatc cagatggacc aatcaaggct gtaatttcct
    38341 taggttggaa agatagggaa acactattca aagccttctt tttattataa taaacggaca
    38401 ggtctgatac ctgtaaaatc gcatctgtca tacggtttcc tttctaacca aagtgaccag
    38461 atacatagtc attggtggac tgtagcttgg cattttggaa aatagttgca gtcttatcat
    38521 actcaatcaa atcacccaag taaaagaagc ctgtatagtc acttgcacga gcagcctgct
    38581 gcatattatg cgttacaatg atgatggtaa agtttttctt gagctcaaac atggtctctt
    38641 ctagttgcat ggtcgcaatc ggatccaagg ctgaggctgg ctcatccatt aagaggatat
    38701 ctggcttaac agagatggca cgagcgatac agagacgttg ttgctgacca cctgataagg
    38761 tcaaggctga cttgtggaga tcgtctttaa cctgatccca gagggcagcc tgacgaaggg
    38821 aggtttctac gatttcatct aggacttgct tatccttaac tccagcacgt tcatgcgcaa
    38881 aggtgatatt acggtaaatt gacttagcaa atggattggg gcgttgaaaa accattccaa
    38941 tgtgtttacg catttcataa acgttgattt ctggacggtt gacatcaatt ccacgataga
    39001 gaatctgccc agttacttta gcaatatcaa tagtatcatt catgcgattg agactgcgta
    39061 agtaggtaga tttccccgac cccgacggac caatcaaagc tgtaatttta tttctttcaa
    39121 attgcatatc aatcccctta atggattcat ttttaccata gtaaacatgg acatccttag
    39181 tagaaagggc tactttttct tcaggaaagg taaggatatg cttctcatcc cagttatatg
    39241 ttgacatggc ttctccttta ggcagcggtt aatttcttgt gtagatagct tccgaactta
    39301 cgagctccaa agttaaaaat caggataaag atcaggagca cagcggcaga acctgctgat
    39361 acaatggttc catctggaat agtgccttca ctattgactt tccagatatg gacagccaag
    39421 gtttctgctt gacggaagat agagatgggg ctagtcacac tgaggatatt ccagttagac
    39481 cagtcaagag ctggcgccga ttgccctgct gtatagatca gagctgcagc ttcgccaaag
    39541 atacgaccag atgccaagac gacacccgtt acaatacctg gaagcgcttc tggaataaca
    39601 acatgaacca ctgtctccca gcgagaaatc ccaagagcca gaccagcctc acgttgggta
    39661 tggtgaacgt gtttcaaact atcctctaca ttacgcgtca tctgaggcaa attaaagact
    39721 gtcaaggcca aggcacctga aatgattgaa aatccatact caaactggac tacaaagatc
    39781 aagtaaccaa agagacccac caccactgat ggtaaagagg acaagatttc aatacaagtc
    39841 cgcacaaagt tggtaacagg acctttttta gcatattcag ccaagtaaat cccagctccc
    39901 atagaaagag gtacagaaat aatcaaggta atgaccaata ggaaaaagga attgtaaagc
    39961 tgaatgccaa tcccaccacc tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccaa
    40021 gagatatggg gcaagccccg aaccaagata tagagaatca aggaagccaa gattgtcaca
    40081 atgatgctag caatcgtata gaggacagct gttgcaagtt tatctaattt cttagcgcgc
    40141 ataatttttc tttcctcttt ctttcgtaat caatttaatc acactgttaa aaactaaact
    40201 catcaagagc agtaccaagg ccagtgacca gagaacatta ttatttacag ttcccatgac
    40261 agtgttccca attcccatag ttaatataga agttaaagtt gcagctggtg tggtcaagga
    40321 agttgggata acagctgagt ttccgacaac catctggata gctaaagcct caccaaaggc
    40381 acgcgccatc ccaaagacca ctgcagtgaa aataccagaa cgggccgcct tcaagatcac
    40441 acgccagata gtctgccagc gagtggctcc catagcgaaa cttgcctcac gataataacg
    40501 aggaaccgca cgcaagctat ccgttgtcat aaaggttacg gtcggcaaaa tcatgacaaa
    40561 gaggacggaa atccctgaca aaatcccaaa accagtccca ccaaagacac tgcgaacaaa
    40621 gggaacgacg acttgcaagc caataaatcc gtacactact gaaggaatcc caaccaggag
    40681 ttcaatagct ggttgcaaaa tcttcgcccc ttttggtgat acttcggtca taaaaactgc
    40741 tgcaccaata gcaaagggtg ttgcgataag ggctgagaga atggtaacga taaaggaacc
    40801 caaaatcata ggaagggcac caaattcttt actagaagga ttccaagttc ctcccaaaag
    40861 aaagtcaaag atattcacac cattgacaaa gaaggtcgac aagccttttt gcgctacgaa
    40921 aaccaaaatc atggccacaa ggatgactat caaagaaaga caggcaaagg tcaaaccttt
    40981 tcctaatttc tccagacgag aattctttga tggaagcaac attttcttag ctaattcttc
    41041 ttgattcatt attgtctccc ttccaacact gtcacagttc cggcagcatc tttttcaacc
    41101 ttcatttcct taatcggaat atacttcaat cctttgacaa tcccttcttg ggtctcatcc
    41161 gagagaacaa aattgagaaa ttctgcagct aactcattgg gctgccccaa tgtatacata
    41221 tgctcataag accacaaggg ccaattattg ctacttatat tttctggact taagtcatag
    41281 ccattcaact tcatgctttt gaccgaatca tctatatagg taagagataa ataagagata
    41341 gctcctggac tttttgatac gattgatttt accgctccat ttgaatcctg ctcctgactt
    41401 tgcatggcag actgaccttc cataatgaca gtatcaaagg tagcacgaga gccagagccg
    41461 gctgcccgat tgataacaga gatgggtaag tccttaccac caacctcttt ccaattggtt
    41521 acctcaccta tgaagatttg acgaagttgc tctgtcgtta gattatcaac atcaacctcc
    41581 ttattgacaa tcagagccaa gccagctacc gcgaccttgt ggtcaacaag agcagaagca
    41641 tcaattccgt ctttttcctc agcaaataca tctgagtttc ctatatcaac tgccccagac
    41701 tgaacctggg acaagcctgt accagaacct cccccttgga cattgaccgt ttttccaaca
    41761 tggatcgtgc caaattcatc tgccgctact tcaaccaagg gttgcaaggc agttgagcca
    41821 acagccgtta tggattctcc acgatcaatc cagctagcac agcctactaa acaagccgtc
    41881 agccaaaaag cgataagaga cagagcaagc ttttttcttt ttttcactgt ttttctcctc
    41941 gaaaataatt atgaatactg tgaatttttt aagtagttct ttatgagttg acgcatgaat
    42001 tcttaccaaa tttctgcgca attgattatt tatataatat aggctatatt actctttcct
    42061 aacctccttt tttcatatgt ggataaaatc tcttgtctat cccttccccc attgtcaccc
    42121 attatagtca tttcgtgtct ctttttcccc tttttaatgc aagggaaatt actctcctta
    42181 gatgataatc taaaagctag aaaggtatct caaatctctc tactctccca gactagttta
    42241 caactaaaag gaaaagattc tattttatga gaaatctagt ttacaagcgg taagaacgct
    42301 aataactaaa cttcttgtac tctttgaaaa tctcttcaaa gcagtgtttt gagctatcta
    42361 tggctagctt cctagtttgc tctttgattt tcatcgagta gtaaaactac atgtgatggc
    42421 aatcaagata tcaagaatca tcctactaaa aaaatccata ctttcactat aacatagaat
    42481 aagatatttg actagcattt tcatttgaat ctgaggcctt ttggaaaata atttttcaaa
    42541 acatttccag taacctttgc aaagcccaag ccattgcctt taaccaaaac ttggtaccaa
    42601 ccatttggca gactttctgc cagctgaacg gtttctccag ccgcatactt gacaaactct
    42661 tcttggccaa tttcaaccga ctgttcgacc tgactcggtt tcaaggctaa accaagagcg
    42721 aaactgggct caaagcgttt cttcttaaaa gtacccagat gcagtccatt gcgagcaatc
    42781 ttgagcttcc ctaaatctgg caaaagttct ggcaagagat aaagctggtc tccaaaaatc
    42841 tgcaagatac ccggtagatt gaccttcaaa tggttttggg caaattcctg ccacaaggca
    42901 acttgttcac ggctgaggtt actcttactt gccttaaatt taggagctgg attgttaccc
    42961 ttaaactgta gatgggcaac aaactgaccc tctcccttaa actgatgagg gtacatccga
    43021 gccgtttctg gcaggtcaat accagctacc attccattga tatgctctac tggcaacaag
    43081 tcaaaatcat actcttccag caaccaattg acaatctctt cgttttcctc gggtgcccag
    43141 gtacaggtcg aataaaccag acgaccacct tcagctaaca tggtcactgc atcctccaga
    43201 atttctcttt gcaagctagc acattgactc ggataatcta agctccaata gtccatagca
    43261 tcaggttgct tacgaaacat tccttcacca gagcaagggg catcaagaac gattaagtca
    43321 aaatagcctt taaagacctt gaccaagcgg tcggcagatt cattggtcac cacgacattt
    43381 gtcgctccaa aacgctccat gttttcaacc aaaatcttag cccgtttgct tgaaatttca
    43441 ttggaaacaa gtagcccctc ccctgctaga taggctgcca gttgagttga tttgcccccc
    43501 ggtgcagcag ccaagtccaa gaccttcata ccaggactgg gttgggctac ttgagccacc
    43561 atttgagcag caggttcttg cgaataaact aaacctgtag catgctcagg cgatttccct
    43621 gaaaccttcc catagtggcc ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc
    43681 tcttctttta agggattgac ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga
    43741 aaatctcttg cctcatctcc tagtatttct ttatattttt caacaaatcc ttctggaaat
    43801 ttcatttaag ttcttttcct ttcgtaaata taggactgaa tttcctcctg catctcaaga
    43861 ggcaccatca tgaccggctg tctggtttga aaatcaggag cttcaccaaa aagggtcaca
    43921 acccgatagc ccagactttc ccctaaaata ctagctgcgg cataatccca tggttgcaga
    43981 taggtgagat aggtcaacaa acgccctgac aaaatcttgg caaaactaat ggccgcactt
    44041 ccatagacac gaacaccaag aaccgctcgg ctcaaatcag ccagccccca ttcattggtt
    44101 tccagcatac cactattccc tgcaatgaga aaatctccaa gtggtttagt tttaaaagaa
    44161 gctaggggcc tatcatttag acaaactgga aattccccac caccgtggta acaatcccct
    44221 ttgaccacat cataaatcag accaaactgt ccctgaccat tttcaaaata agccatcata
    44281 acagcaaaat cttcctgctg ggctacaaaa ttattggtac catcaatggg atcaatgacc
    44341 caaaccttgc cctcttgaac cgaggctcgc agacaacctt cttcagcaca aatcttatcc
    44401 tcaggataac gggacaaaat ctcaccaacc aagagttcct gaacttcttt gtccagtctg
    44461 gtcaccaaat ctgttggaga ggacttggtt tcaacacgca agtcttcctg catatggtca
    44521 agaatgtact gacctgcttt cttaacaagc tctttagcaa attcaaattt actttccaag
    44581 agaaatcttt ccttcccctt tttctttggc agcctgaact gctcggtaaa gtgaatagcc
    44641 actaaccgtt tcaaattctc gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc
    44701 tttgaatccc ttataggagt ccagtaactt tttagcctct actttgcctt cataggcagc
    44761 ttcaacatca ttaaaaaaag aaagcactga agcaagttct tcagtgctcc acgacaaatc
    44821 tagtgggtaa ctatactgtt tgttcattaa ctaataccag ctctcattct tgcttctttt
    44881 agttcttgct tacgataact acgagggaga aaagcacgaa tctcatcttc attaaaaccg
    44941 atttgcatac gcttggcatc aataataatt ggacgacgca aaagactagg atactgctca
    45001 atcaaatgaa gcaattccga taccgaaata ctctctacat caatattcaa tttttgaaaa
    45061 atttttgaac gagttgaaat gatgtcatca gtaccatttt cggtcaagga aaggatttgt
    45121 tgcaattctt ttcttgttaa aggactggtc ataatattgt gttccacaaa gggaacctta
    45181 tgtttttcta accaggcctt agccttacga catgatgtac agctcggtga tagaaatagt
    45241 gtaatcatgc ttttctcttc ttatctatac tttgctactt ctattataca aaaaaataag
    45301 gcgcttgact agggattttt agaaaaaaaa gcctattttt caagaaaaat aggctgtttg
    45361 cgaacgattg acacaattgg atttggttaa ttcactctta acgatggttt taaacgatat
    45421 atatttttat atatgcaaat taaaaacatc tttcatttca tttcctacga cttttcagac
    45481 acagatagcc aaagaagctt tcatagaggg caaaaaagag gaggaaggca tgaagaaaga
    45541 aggtctctgg caaaatcata ataacaggat ccttggctgg atcaaaaagc caggtatcat
    45601 ctcccacaaa gagaatttga tggaaaagag taaagaattg gtcaaaacca atcaaaactc
    45661 ccccaagtcc aatcatcaca ggtaagacta ctagagtcag gagacttttt cgataaagag
    45721 acaaaaagtc ctttttcaca attctattga caaagacata gaaacttggc agtgtcacta
    45781 gagctactag ctgaaccaaa tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag
    45841 ctgctgacga acgaaaatca ggcatctgta agacctgact aaaaggattg gtcagataat
    45901 tcatcaagat atgaaaattg tattgaatgg tttctggttt tagatagact cgattcgtta
    45961 agtttagcca ctgaatctcc ataggataga aaatccaagc cagataaatg gtcagaagga
    46021 ttgagaggga gaggagaaag agcatagagc cccaaaaggt caatttagtt ttcatcaaaa
    46081 tcccactccg caaggctaga aaccacatgt gtcggtgcga ttggcaggcc agctacttct
    46141 tctgccttag taaaacctgt cgtcaccaag agcgttggaa tgccattgtc aatcccagcc
    46201 cggatatcag tcaaataatt gtccccaacc atgattaact cttcacgttc caaacctaag
    46261 tgctcaaccg ccttgtccat aatgatggca ttgggttttc cgatataaac cggcttcact
    46321 cgtgtcgcta cttcaagcag cgtaatcagt gagccagcac ctggcaaaag accgcgttcc
    46381 gtcgggatgt tgaggtcagg attggttccg ataaaatggg cacccttttg aatagcaaga
    46441 gttgctgtgg caaatttttc atagtcgact tgccaatcca gaccaactac cacgtaggca
    46501 gggttttcct tgtcttccac ataaccagcc gccttgatgg cttccttgag tcctgcttct
    46561 ccgacgacat agacggtctt ttcaagcccc aaatcattca tatagtcgat ggttgctaaa
    46621 gtcgctgtgt agacagtcga taggggcgta tcgatattaa aattctgagc caacatctcc
    46681 ttaacactct ctggagtgcg ggttgtattg ttggttacaa agagataggg aatgtcccgc
    46741 ttttgcaatt catgaacaaa agtctctcca gcagggattc ggtctttccc cttataaatg
    46801 gttccgtcta aatcaattaa atagccttta tatttcatct atttctccct aagccttttt
    46861 tatttcttgc caagtaatga ttgcttgggc attgataacc ccatcacttg taatttcatg
    46921 cttgctttcc agtccagtcc gttcaacagc cgatgtaatc accccacctg gtcgaacttc
    46981 cttgacatac ttgaggttga ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat
    47041 gacctcaaaa atccagtcca agtatttact gttattgaca tgaccattca tatccaagtc
    47101 gtaaaaacga acatggtaat ccttgctgat cggctcttcc aaggattcat acttcggtcc
    47161 acggataagt tttttatcaa aatcagactg gtaaggagcc acaatctcag gttcaacaac
    47221 atggactttt cgactgtcgc ggtccatgag aacaaaggtc gccatcatgt ggatgagctc
    47281 ctgccccgct tcattataaa tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa
    47341 ggcttccgtt tcgatggtaa tttcttccgc aaaacgaggc aaacgaacca cctcaatatc
    47401 atattctgcg ataatccaga ccagattata gtcttccaaa atggccttat cactaactcc
    47461 cagttcaatc gattgcatcc ctgaaacttg cagtgacagc aaaatcacat ctggaagttt
    47521 gatatgaccg ttcatatcag ccatatcaaa aggaattttc attttcattt gataagttaa
    47581 gcccatgatc ctactccaaa ataaatcgtt ctgctacagt atctcccaaa aagagacctc
    47641 tctttgtcat gcgaacgtgg tcaccctcaa tctgcatgag gccttgttga accaagtctc
    47701 tgacaatttc tccataaagt ccagcaaaag actgtccaaa tttttcctca aatcgcgcca
    47761 tggaaacccc ggatttcttg cggagtccca agaacatttc ttcttccatt tgctcctttt
    47821 gactcaggtg atcttctgta atacaagcat tgccttcctc aaccgcactg agataatgac
    47881 gaatgggacc ataattttta taacgtactc cattgacata accagatgcc cctgcaccaa
    47941 taccatagta ttcagcattg tcccagtaca tgagattatg acgactttca aagccgggtt
    48001 tggagaaatt agaaatctca taatgctcaa aacccgctcg ctccagctct gcaatgatgt
    48061 actcaaacat ctccgcttct agttcctcct taggcagagg caatttccca cgtcgcatcc
    48121 ggttcataaa gaccgtatgg ttttctaaaa tcaaactata caaactcatg tggggaatat
    48181 ccaatccaat ggctttagcc acattttcct ttacttgctc catggtctga ccaggcagag
    48241 cataaatcaa atcaatggag atgttgtcaa aaccagccag tttcaggcga tcgatatttt
    48301 cataaatatc cttctccaaa tgactgcgcc caatcttttt caacatctta tcatcaaagg
    48361 tctggacacc tagcgaaaca cgattgacag ccgaattttt caaaacagct atcttatccg
    48421 catccaaatc gcctggattg gcttcaatgg tcaactcttc caagacagac aaatccaagt
    48481 ttttagtcaa gccattcagt aacacctcca gttgcggagc cgacagggct gtcggtgttc
    48541 caccaccgat ataaagggtt gacaactttt caatatcata agaacgaaac tcttccagca
    48601 gatgctctaa atagctgtcg actggctgat ttttgatgaa gacctttgaa aaatcacaat
    48661 aataacaaat ctgggtacaa aatgggatgt gcacataggc tgacgttggt tttttctgca
    48721 tagtaattat tataccacaa agactagatt ccagataaaa atcaccatcc ccagatacat
    48781 agtccgttcg gagatggtga tggtttattc ttctgttata tcaatcacaa tctcttctga
    48841 gtcatcaaga gcttcggctt tttcttgcca ttgttccttg agattattta attgattttt
    48901 tgatgcttct gtcgcttgaa aagcatagga tttagcttga gcaagtatac tgtccacagt
    48961 gatttcacct gactcaacct gttcttttgt tttcagaaca aaatctgtag cctgctcctt
    49021 aacttctgtc agtttttcac agacttgctc cttggcatac tccggatctt ctctcaaatc
    49081 atctagaaaa tcttgagcct gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa
    49141 ggcaagagct gcacctgaaa cggttcctaa aaggattgag gataatttac ccataaggat
    49201 tctccttttt tattttttga aaaatttact tgcaagacga agagctgaca gacttgcacc
    49261 agtcttgagt gtttttgaac cagctgatga agctttcttg ctcaagacac gcgcatggtc
    49321 attgaggtct gaaacagata gagataaatc tgcaacagca ctgaagagtg gatcaatcgt
    49381 agccaccttg acattgatat catctgccaa gacattgacc ttagccaaca actcattggt
    49441 atgatgcaag gtcacatcca catctgaagt caaggtttta atcgtctttt ctgtttcatc
    49501 gatgacacga ccaagctttt gtacagtaat gatcagatag accaaaaaga caatcaaagc
    49561 tagggcaaca agaatatatg caacttctaa catttagttt tcctcctctg taatatagta
    49621 aggggccttc tttcgatttt gataaataac gatcattata ccgagaccga taaggacaac
    49681 tgacagccat tgggacactc gaaggccgaa gaacatgaga ctatctgttc gcataccttc
    49741 gatgaccata cgaccgaaac cataccaaat caagtaaaag gccgtgatat gacctcgtct
    49801 gagactcttc catttccgtc taaaaatcag aatcaaggca aagccaagca gattccatag
    49861 agactcataa aggaaagtcg gttgacggta gctcccctca atatacatct ggtcacggat
    49921 aaagccaggt agataatcaa gattatccac tgttgcacca taagcttctt ggttaaagaa
    49981 attaccccaa cgccccaaac tttgagcaat cataacgcta ggcgccgcaa tatctagaaa
    50041 atcccaagta ttgatgagtt tacggtcagc aaagatatag agcacaagag ccccagttat
    50101 caaaccaccg taaatggcca aaccaccatt ccaaatggca aaaatctctc ctaaattctg
    50161 actatagtaa tcaaatcgga aaataacata gtagagacga gctcctaaaa tagccaaggg
    50221 aaaggctact aagataaaat ctaaaatatc gtctggtatg atcttctttc taggtgcttc
    50281 tttcatggtc aaataaaccg caagaatcaa gcctgtcaca atacataagg cataccaacg
    50341 aatggctagg ggtcctagtt gaatagcaat tggatcaagc attttgcacc tcatttcgag
    50401 cgattagact tgtcagtcgt tcgtcgaaca aacgggtcgc atcaaagccc atttccttgg
    50461 cacgataatt catggcagct gcctcaatca caacagagat attacgacct gttttaactg
    50521 gaatacgaat acgaggaatg gctacgccag aaacttcaag ttcctctgca ttgtttccaa
    50581 gacgatcaaa ggtcttatgt gtatcgtaat tttccaaata gacagcaagc tgaacctgtg
    50641 aagaatcctt gacagcactc gcaccgtaga gactcataac atcgataata ccaaccccac
    50701 gaatttcaat caagtgtttc aaaatttcag ctggttcacc ccagagagta atctcatcct
    50761 tggcaaagat atcgacacgg tcatcggcta ccaaacggtg accacgtttg acaagctcaa
    50821 gacctgtctc gctcttacca attccactat ctccctgaat caagacgccc atcccataaa
    50881 tatccatcaa gacaccgtgc acactggtac gttctgccaa acgagaatcc agatagctag
    50941 ataactctcc agataaacga ctggtagctg cacggctggt taaaatagca atcttacatt
    51001 ctctagcagc ctttaacatc tcctctggaa ccaccaaacc acgggcaaca atgactgctg
    51061 gtgtctcagg tagaaacatt tttttcaaaa cttcataacg gctgttggaa ggcatgctga
    51121 tcagataaga ccactccttc atccccaaaa gttgaatccg ctctggtgta tagtagtcaa
    51181 aatagcctgt catttcaaga ccaggtcgcg taatatccgc tatattgatt tccttttcaa
    51241 gcaattctgg ttcaccatag acaatgtcta gtctaagctt ttcaatcact tcttttacta
    51301 aaaccgacat catttcctcc ttcaaatgag ttcttctctc tattatatca aattgtagga
    51361 ggaagtttca gatttttgca ggctttggag tatttattta aaagaaaaag gactagattt
    51421 ctctagcctt tcattccaat tagaattttt tacgtttacg agctacttct gatttacgtt
    51481 tacgttttac agaaggtttt tcatagaatt cacgtttgcg tgtttcttga agagtaccag
    51541 ctttagtaac cgcacgtttg aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta
    51601 ctactgtttt agacattttt ttcactccct tcaagttcaa tatctatttc attctacacg
    51661 taaaaggaat aattgtcaag caaaaatgcg gtttaatttt gattttttct tccatttata
    51721 caagagttga aagcgttcaa tagaacattg cttttttatt tttcgagtaa gctaagcgct
    51781 tcagcatctg cgatgatggt tacatcaggg tgattttgga ggctacttgc aggtaggttc
    51841 tcagtcactg ggccagatac tgttccggca atggcttctg ctttcgactc accgtaagca
    51901 aaaagaataa tagacttggc atccaaaatg tttttaatcc ccattgaaat agcttgggtt
    51961 gggacgtctt caatcttggc aaagaagcgt gcattggctt caatagtaga ctggtcaagt
    52021 tctactagat gcgtttgact gtcaaatgga gtaccaggct cattaaagcc gatatgccca
    52081 ttgcgaccaa ttcccaagat ttggaggtca actggatggt cagccaaaat ttggttgtag
    52141 cgttcaactt cagcttcagc attgtcctta acaccacgag gcaagaaact ttctttaaat
    52201 ggtttttggt tgaacaagtt ttcttgcatg aagtaacgat aagactgtgg attgtcccca
    52261 tcaaggccca catactcatc aaggttgaca ctggttagat ttgaaaaatc aaggtcactc
    52321 tcaacaattt ccttgtaaaa ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga
    52381 gctccattag ccaatttttc cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg
    52441 ttttcaactt taataacttt catcttttca tcctccattt ctgtctatat ttattatatg
    52501 gtatagacca atttttgtca agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac
    52561 ttgaaacgtg ttataatgga taggattata acttagaaag aatgaacaaa tatatgaata
    52621 cagctgattt tgatttccac ttgccagagg aattgattgc ccaaacgccc cttgaaaaac
    52681 gtgatgcctc caaactcctc atcgtcaacc gtgagacagg agaaatgcaa gataaacatt
    52741 tccactctat tattgatatg ctggaacctg gtgatgccct tgtcatgaac gacacccgag
    52801 ttctccctgc ccgcctctat ggtcaaaaaa tggagacagg aggtcatgtg gaacttctcc
    52861 tccttaagaa cactagtgga gacgagtggg aagttctggc taaacctgcc aaacgcctca
    52921 aggtcggtac tcgtatcagc tttggtgatg gccgcctcag cgctgtcgtt acagaagaat
    52981 tgacccacgg gggacgcatt gtccgctttg aataccaagg aattttccta gaagtcttgg
    53041 aaagtctggg agaaatgcct ctgccacctt atatccacga aaaattagat gaccgtgaac
    53101 gttatcaaac cgtctacgcc aaggaaagcg gctctgctgc agcaccgact gctggtcttc
    53161 acttcaccaa agaactgctg gcagaaatcc aagctaaggg tgttcatcta gtctatctga
    53221 ctctccatgt cggactcgga acctttagac ctgtttctgt ggataatctg gacgaacacg
    53281 aaatgcactc agagttctat caactttctg aggaagctgc tgccaccctt cgctctgtca
    53341 aagaaaatgg tggtcgcgtc atcgctgtcg gaaccacttc tatccgcacc ttggaaacta
    53401 ttggttccaa gtttgatggg caaatccaag cagattctgg ttggaccaat atctttatca
    53461 aacctgggta tgagtggaag gtcgtggatg ccttctcaac caacttccat ctgccaaaat
    53521 caactctggt catgttggtt tctgcctttg caggccgtga attagtctta gatgcctacc
    53581 accatgccat ccaagaacac taccgcttct tcagttttgg tgacgccatg tttatttatt
    53641 gagaaagaat ttctctaatt cttctaatac caataaatcg ctaagatatt atttcaaaga
    53701 acatctacaa ttgaaactct agctagctgt agaagacgcc tagtacattg aaattaaaat
    53761 gcttccccct agcttcgaaa atattgccat agattgcgtt gactctccaa attgattcat
    53821 ctatatttta tttcagcttc ctatattttc ttcgctgttt gtaaatcaaa atgcaagaca
    53881 catgagtagc accatatttg ttactcttat ctgtcctctc aagagactat tatgagttat
    53941 ttcagaatca ttcactactt tgaccctgac tctccttagt ctcaaaatca aagacttata
    54001 ctcttcaaaa atctcttcaa accgcgtcaa cgtcaccttg gattatatat gtgactgact
    54061 tcgtcagttc tatctacaac ctcaaagcag tactttgagc aacctgcgac tagttttcta
    54121 gtttgctctt tgattttcat tgagtattaa acaaaaagtg aacaaatctg aattctaatg
    54181 tacagaagac taggcttgtt cactttttta tagtcgctat aagatgacct tatctatagc
    54241 tttttatata taattatata ttcagacata ctattatcaa ttttgtcgca gggaggaatc
    54301 tgttaacgca cccattcacc attatcattg actctatagc catctatact tgtattgacc
    54361 gctaactcac ccgatgcatt tacataatac catttaccac caacttggaa ccattgattg
    54421 actttcatag aaccgttgct gttgaggtag taccataaac cattaacttg tacccaacct
    54481 gttgccatgg aaccatcagt attataaaaa taccacatac cattttcttg tttccagtct
    54541 gttgttggag caactgcttt agctggttct actgctacat ctgttccttg gttagatgta
    54601 acagatacag gatacgaagg aatagatgat tgctcaggaa caacaacttt ttcaggttct
    54661 ctcgtccctc tccttatacg tctttttacc atctctttag taatttgacg agaagtagtt
    54721 tcttcaattg ttccatcacg ttcatctaca gtatagattg tagtaagagt aatttaccaa
    54781 tttctcctac ttcttctact tcttgacttt tatcaagagt tgggccatcg agatattctg
    54841 tttcgattgg aatttcttgg acaagaactt ggggcttggt tcttttttta acaactcttg
    54901 tttgagagtc tttttttgac ttaaagtact ctcagttact tgtccactct ttccatctac
    54961 attataagtt atcgttgtaa ctgttttccc attctttcct agagtaatct cttgctcctg
    55021 tcctgcagaa aggtcattgt ctgcttcata tttagtagca aatggaacaa gaacttcttc
    55081 aaccttgctt ttagctggaa ctttgataac tgtatccgtg gcttcttttc tatcaacagt
    55141 aacctgttcg gtaacataac cagtctctgg attaacatcg taggtccttg tcgtagttac
    55201 atagccatcc tctccatcaa ttgtaacagg attttcacta cggtcttttg tttcatcttt
    55261 ttcataacga attcgcgtac ttgaaatttt cttggttact accttaggtt tagtcgctac
    55321 ttttacaata atatccccat tgtcagcgtc atcatactct attccctctt ctttatctct
    55381 agtatcatct ctgacatatt gaatcccatc agcagcatga acaaaacttg tattcagatt
    55441 cctcctaaaa ataaagttag cccgattacc gcagaaccaa aaatctttcc gagtttacgt
    55501 attgcatagc gcttattagt attagatttt gccattacat cctacttcta gtatagcatc
    55561 ttttctatca aacgttaaac aatatacttt atatataaaa tagacttaga atgatatatt
    55621 gattattgaa ctaacacttt aactatatcg taatcaatct catatataaa ggattgcaga
    55681 catcttatct aaatacatgc taatatattt agatacaaac attccaactt gataattttc
    55741 actcatcttt catcattcct tatacaacta tgcagtataa atagaatagt tttctcatca
    55801 gaatgagact attttaatat tagataattt gatagaaaaa acatgaataa aattggttga
    55861 atttaattcc ctaactcgat agaggattct attttaaatt taacaacagc taggattaca
    55921 ctataaaaag tacattacca cctgttcggc tggagaatct agtcgattag ctccctctta
    55981 gttacaagct tcaagcgatt ttttaactaa cactaaacc
//
LOCUS       DAVBOU010000010        47724 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBOU010000010 DAVBOU010000000
VERSION     DAVBOU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.010"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(790..1050)
                     /locus_tag="VQ879_000596"
     CDS             complement(790..1050)
                     /locus_tag="VQ879_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142805.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(1109..1660)
                     /locus_tag="VQ879_000597"
     CDS             complement(1109..1660)
                     /locus_tag="VQ879_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142806.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1650..1847)
                     /locus_tag="VQ879_000598"
     CDS             complement(1650..1847)
                     /locus_tag="VQ879_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142807.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1851..2435)
                     /locus_tag="VQ879_000599"
     CDS             complement(1851..2435)
                     /locus_tag="VQ879_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142808.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2833..3258)
                     /locus_tag="VQ879_000600"
     CDS             complement(2833..3258)
                     /locus_tag="VQ879_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142809.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3387..3746)
                     /locus_tag="VQ879_000601"
     CDS             complement(3387..3746)
                     /locus_tag="VQ879_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142810.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            complement(3792..3998)
                     /locus_tag="VQ879_000602"
     CDS             complement(3792..3998)
                     /locus_tag="VQ879_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142811.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            complement(3985..4146)
                     /locus_tag="VQ879_000603"
     CDS             complement(3985..4146)
                     /locus_tag="VQ879_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3142812.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4505..5461)
                     /gene="lytA"
                     /locus_tag="VQ879_000604"
     CDS             complement(4505..5461)
                     /gene="lytA"
                     /locus_tag="VQ879_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3142813.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(5837..7207)
                     /locus_tag="VQ879_000605"
     CDS             complement(5837..7207)
                     /locus_tag="VQ879_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3142814.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(7514..8680)
                     /gene="recA"
                     /locus_tag="VQ879_000606"
     CDS             complement(7514..8680)
                     /gene="recA"
                     /locus_tag="VQ879_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3142815.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            complement(8735..9991)
                     /locus_tag="VQ879_000607"
     CDS             complement(8735..9991)
                     /locus_tag="VQ879_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3142816.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(10076..11092)
                     /locus_tag="VQ879_000608"
     CDS             complement(10076..11092)
                     /locus_tag="VQ879_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3142817.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(11100..11618)
                     /locus_tag="VQ879_000609"
     CDS             complement(11100..11618)
                     /locus_tag="VQ879_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142818.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(11608..12051)
                     /gene="tsaE"
                     /locus_tag="VQ879_000610"
     CDS             complement(11608..12051)
                     /gene="tsaE"
                     /locus_tag="VQ879_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3142819.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            complement(12137..12757)
                     /locus_tag="VQ879_000611"
     CDS             complement(12137..12757)
                     /locus_tag="VQ879_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142820.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(13140..14003)
                     /locus_tag="VQ879_000612"
     CDS             complement(13140..14003)
                     /locus_tag="VQ879_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3142821.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            14507..16522
                     /locus_tag="VQ879_000613"
     CDS             14507..16522
                     /locus_tag="VQ879_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3142822.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            16524..17156
                     /locus_tag="VQ879_000614"
     CDS             16524..17156
                     /locus_tag="VQ879_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142823.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            17297..17575
                     /locus_tag="VQ879_000615"
     CDS             17297..17575
                     /locus_tag="VQ879_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3142824.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(18084..18497)
                     /gene="ndk"
                     /locus_tag="VQ879_000616"
     CDS             complement(18084..18497)
                     /gene="ndk"
                     /locus_tag="VQ879_000616"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3142825.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(18608..22285)
                     /gene="rpoC"
                     /locus_tag="VQ879_000617"
     CDS             complement(18608..22285)
                     /gene="rpoC"
                     /locus_tag="VQ879_000617"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3142826.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKLIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(22318..25929)
                     /gene="rpoB"
                     /locus_tag="VQ879_000618"
     CDS             complement(22318..25929)
                     /gene="rpoB"
                     /locus_tag="VQ879_000618"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3142827.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            26345..26415
                     /locus_tag="VQ879_000619"
     tRNA            26345..26415
                     /locus_tag="VQ879_000619"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26377..26379,aa:Cys,seq:gca)
     gene            complement(26613..27944)
                     /locus_tag="VQ879_000620"
     CDS             complement(26613..27944)
                     /locus_tag="VQ879_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3142828.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(28235..29059)
                     /gene="endA"
                     /locus_tag="VQ879_000621"
     CDS             complement(28235..29059)
                     /gene="endA"
                     /locus_tag="VQ879_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3142829.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(29098..29286)
                     /locus_tag="VQ879_000622"
     CDS             complement(29098..29286)
                     /locus_tag="VQ879_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3142830.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(29279..30562)
                     /gene="murA"
                     /locus_tag="VQ879_000623"
     CDS             complement(29279..30562)
                     /gene="murA"
                     /locus_tag="VQ879_000623"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3142831.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(30586..30816)
                     /locus_tag="VQ879_000624"
     CDS             complement(30586..30816)
                     /locus_tag="VQ879_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3142832.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(30874..31911)
                     /locus_tag="VQ879_000625"
     CDS             complement(30874..31911)
                     /locus_tag="VQ879_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3142833.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(31895..32383)
                     /gene="coaD"
                     /locus_tag="VQ879_000626"
     CDS             complement(31895..32383)
                     /gene="coaD"
                     /locus_tag="VQ879_000626"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3142834.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(32373..32912)
                     /gene="rsmD"
                     /locus_tag="VQ879_000627"
     CDS             complement(32373..32912)
                     /gene="rsmD"
                     /locus_tag="VQ879_000627"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3142835.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(32977..33969)
                     /locus_tag="VQ879_000628"
     CDS             complement(32977..33969)
                     /locus_tag="VQ879_000628"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3142836.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(34080..34763)
                     /locus_tag="VQ879_000629"
     CDS             complement(34080..34763)
                     /locus_tag="VQ879_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3142837.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(34819..35559)
                     /locus_tag="VQ879_000630"
     CDS             complement(34819..35559)
                     /locus_tag="VQ879_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3142838.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            35593..35871
                     /locus_tag="VQ879_000631"
     CDS             35593..35871
                     /locus_tag="VQ879_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3142839.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            35949..36875
                     /gene="yidC"
                     /locus_tag="VQ879_000632"
     CDS             35949..36875
                     /gene="yidC"
                     /locus_tag="VQ879_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3142840.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(36950..37744)
                     /gene="pflA"
                     /locus_tag="VQ879_000633"
     CDS             complement(36950..37744)
                     /gene="pflA"
                     /locus_tag="VQ879_000633"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3142841.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(37870..39120)
                     /locus_tag="VQ879_000634"
     CDS             complement(37870..39120)
                     /locus_tag="VQ879_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3142842.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(39187..40014)
                     /gene="purR"
                     /locus_tag="VQ879_000635"
     CDS             complement(39187..40014)
                     /gene="purR"
                     /locus_tag="VQ879_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3142843.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(40281..41222)
                     /locus_tag="VQ879_000636"
     CDS             complement(40281..41222)
                     /locus_tag="VQ879_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3142844.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(41212..42468)
                     /locus_tag="VQ879_000637"
     CDS             complement(41212..42468)
                     /locus_tag="VQ879_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3142845.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(42470..43132)
                     /locus_tag="VQ879_000638"
     CDS             complement(42470..43132)
                     /locus_tag="VQ879_000638"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3142846.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(43095..43751)
                     /locus_tag="VQ879_000639"
     CDS             complement(43095..43751)
                     /locus_tag="VQ879_000639"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3142847.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(43762..44640)
                     /gene="rsgA"
                     /locus_tag="VQ879_000640"
     CDS             complement(43762..44640)
                     /gene="rsgA"
                     /locus_tag="VQ879_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3142848.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(45233..46006)
                     /locus_tag="VQ879_000641"
     CDS             complement(45233..46006)
                     /locus_tag="VQ879_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3142849.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(46696..47568)
                     /gene="rsmA"
                     /locus_tag="VQ879_000642"
     CDS             complement(46696..47568)
                     /gene="rsmA"
                     /locus_tag="VQ879_000642"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3142850.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
BASE COUNT        14021 a        10594 c         8797 g        14312 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct attatatata tgcacagaca
       61 tatgaaatct ttttgataca gccttctttt tacatagaga gacagcagtt atgatatatt
      121 tatccattca caacatcttc tgtaccaata ctacaataat tggtacattt tgattacaca
      181 atcgtttcaa aaaatatgat ggaagactga gtattttata gtaattccct tcctatcaac
      241 tagatcaacc agttgagtgt tgaatgttga aacaccctag cctcagcaaa ggactatgat
      301 cagcatttcc tagccaatag gacgctccaa atcacctatt ctaagtccat cactagcttg
      361 gtcagtaaga tacagactgc aaggcaagac tgacgtggtt gatgagattt tggaagagta
      421 ttacaatcat agattcacca gtagacttga ccgcagattt aactatagta gattgaaact
      481 agaatagtac acttctgctt ctaaaacatt gttagaaatc gatttgactg tcctgatcaa
      541 tttgtcctgt tctcgtttca ttttactata ctaaaaaacc acctgaaaca aatcaagtga
      601 ctagaggata aaaacaaaga ctgggcaaaa agttttgaaa agcaaaaaac gcataatatc
      661 aggtcttgaa aaaccttgat actatacgtt tgattgtggg aagattgact tcattttctc
      721 ctgaaattga agttttttct agtttccagg tatagacgaa ttcaatatag ccatctcgct
      781 acaattattt taaccatcga aaaaattttt cagaatttca aaaatttcat tttgatctaa
      841 tgaaatgtca tcattttgaa gaatagttga cttcacaagc tctaattcta tcacaaagcg
      901 gtgcatgtct gcttttaccg cactacttga tgttatagcc gataactttt catctcctag
      961 caaggaagct gtcaaacggg taaggtcatt caaatgcttt ttaatggact tacttaaacc
     1021 ttgagcacct gtagcagagc gttccctcat atccagccaa gctttagcct taaaaataat
     1081 taatactcaa tgaaaatcaa agagcaaact aggaagctag ctgcaggctg ctcaaaacac
     1141 tgttttgagg ttgtagatgg aagctgacgt ggtttgaaga gattttcgaa gagtatagac
     1201 cacaattact caataccgaa tacccctgaa tggtttcttt ttcatgcacc aatatattat
     1261 aataatcttc atccaataat aaggctgata aactagcatc ttggtcaaaa tgtaagggaa
     1321 tttctcgacc gtccttcttt aatggatatt ctggtaagat actaaatagt tcaatcatag
     1381 aaggaaactc agaattagtt gttgtaaatc gaaaaagctg cgctttctca tctttctgac
     1441 ttccttgata ctctcccaat tctaaaaaat gattcaaggt agtataaaat tccttatttt
     1501 ttacttcatc aatgatgacc atatcataat cttttgttgt gcgactttta aatccttgcg
     1561 aatccaatac gatagaggta gcagttcccc caatcagaac ataatagttc tgaaaatccg
     1621 caaacatttc ttgaaaaata actttcgtat tagctggcat catcttctcc cagatactgt
     1681 aatatcatat tttctagtgc ttcactctct tcctctatac gtgggtcatc atcatctttt
     1741 aaggtcaaat aaagagaaat cggatctaca aattgtttat catgattatt tttaaaatca
     1801 ttccaaaact cagatacaaa aggacgatat ttccatatct ctagcatctt tcattttaaa
     1861 acatgctgag aaagtggcaa ggataactga ttgaattttc tctgccatat gacatagcta
     1921 gtattttcat ccgtttcagc taaaaaagtt gaatgcgaca aagcataagc accaccatat
     1981 agaaggttag aaacagattt tatctgcttt atatcgccat ctggcaataa aaaggcaatc
     2041 cacgttaatt gttcgctagg tattaattcc ttagggactt cagtatcatt cgcattcagt
     2101 actagtccca atgtagggaa gaagaggttt cccttaaagt ctacaaacgg aactctagct
     2161 tgaagtaatt gctttttttc accgtctgat aacttcgaaa acaccaaaac aacatccata
     2221 ttggctttat cacccatagt gcgagcctga gtaacaaatg aactcaaact cccccttctc
     2281 ttttctttaa tcaataaaaa tgattcctta tgaaaagtca tttgagtata ctcaaacttt
     2341 tttacaaaac tgattggtaa agtcaaagtc agttcctcaa tactgacatc aacataaaag
     2401 gattgaaata ttgacattat ctttttgaca ttcatgtttt ttccttattc tatcattttt
     2461 attatatttt atcattcggt ataataaaat ataagttttt tgataaaata accaaaaact
     2521 actcgctatc ccctctcaca ttaccctaca tatcgtttga catgcgactg atagttcagg
     2581 aaaacttcaa ggagaacttt tctctcatcc actatgcagg acttactatt tcacttctac
     2641 tcctataggc tcaatttgac atttttcttt ttcgaattgc tcatatgcct cctgaatagt
     2701 gagttcgatt tatccaaatt tatttttgtc tattttgatg aatacttcca cgaagaatga
     2761 atttgcacca attttccttc tctttttaag catattattc cagatatgat tgccctcttg
     2821 ttcagtaata aattacgctt taaacgcttc aatcagtata tctcctgttg tcatatgttc
     2881 taaagaaaat tcttctacat atggtttaac atctcttagg ttattacttc ctaatatccc
     2941 attatgcttt ttcgctaagg aaatagatgc cccttctcct ttaccaataa tcttgttact
     3001 atcatgattt cttgttaaat ctctatataa tgcgtattct tcagttccaa tgtctatgct
     3061 cacaatctca gctgaaccct tagctaccaa ctgatctatc ctagatttta aatggggaat
     3121 tgtaggtata ttgatttcat catacacctc ttgtggaata acaattttac ccaaatagag
     3181 cttttctaaa agatgttcaa tgccaaccca taaaaatact gaaatacaat ctgcatcaat
     3241 aaatacacga ctagtcaaac gacaactccc ccctcttcat ctagcccata tacaatatca
     3301 tatctgaaag catctagtaa cagttcctca tacttccctt gcgaaattct gttattttct
     3361 aaaagttgtt cagttgaatt aatatattat cctaatgcca tttctttttt actttctgac
     3421 aaaggacgat ataaacttgt atcatagcct aatcttgaag ctgtctctat aacactaata
     3481 tccatatttt taatttcttc tgcatcaagg tatccatcat tcctcaatct atataacata
     3541 gctttatgac tgataccata aaactgaccc aattttataa tatcttctac ttcaagatga
     3601 gttctattgg cattttctct gatttcctca accatcctat acagtgaaga tgggaaaatt
     3661 aaaaaataag aagcaaactg atccgctttt ctttcagttt catctccttc accaatcaag
     3721 ataagactga ctgaactctt cttcacctca tcataataaa gatgatacag tccatgtgct
     3781 aaagaaaatc tttacctttc taatggcatg tctgaattga ctgcaatgag actgaactga
     3841 gttcctttat aacagactcc gctaatattc tttccgagtc cataaaatac cagcgtcaaa
     3901 ttttctatct tttgtaccaa tttaaaaata tctatcggcg attcaccatc agctcccaac
     3961 ttttttctaa gatttgaagc tttattactt aaatccattc gtgatattcc tttcaccttt
     4021 ttccattttg gcaatcatgc tttgattcaa agacaaatac tcagcaatct tatcttgagt
     4081 aagatttgaa gatattctaa gttcttttat tctttttcca acatcacata catttatcac
     4141 atacatttat catattcata cacctctcat aaaaagaata gcacactctt gtcataattt
     4201 tttaaataaa aaaattatga caaaacaagg aagcaattta ttgatgctgc ttaaaaatct
     4261 aaaattgatg agttcctatc aaaaatcgta tcttcaacct caaaacagta cttaaagcta
     4321 tccgactcgg tttacattgt caaatttaga ttttatttga gcataacttt ctagtttgct
     4381 ttctgatttt tgtttaatat agtagcaaac attgaaggaa atatctccac aaaaaaacgc
     4441 atactattaa gctttttcaa gacctaataa tatgcgctgt tctgatttga aagacattcc
     4501 attattattt tactgtaatc aagccatctg gctctactgt gaattctggc ttgtctgcca
     4561 gtgttccgtc tggtttgagg tagtaccagc ctgttccgtc cgctgactgg ataaaggcat
     4621 ttgataccat ggcgccttct ttagcgtcta agtagtacca agtgtccttg tacttgaccc
     4681 agcctgtctt catggcacct tcttcgttga aatagtacca cttatcagcg attttcttcc
     4741 agcctgtagc catttcgcct gagttgtcga accagtacca gttgccgtct gtgtgcttcc
     4801 tccagcggtc tgcaagcata tagcctgaac tgtcaaagta gtaccaagtg ccattgattt
     4861 tctcaaactt gtcttttgga taagagccgt ctgaatgtac gtaccagtag ccagtgtcat
     4921 tcttctgcca gcctgtttca atcgtcaagc cgttctcaat atcatactta aactgctcac
     4981 ggctaatgcc ccattttgcc aagtaagggt atggatccac atggtctgag tggttgtttg
     5041 gttggttatt cgtgcaatac tcgtgcgttt taattccagc taaactccct gtatcaagcg
     5101 ttttcggcaa acctgcttca tctgctagat tgcgtaagag ttcgatataa aggcggtaat
     5161 ccgtcatgaa ctcttcttta gttgaatggc tttcaatcag ttcaaccgct gcataggtct
     5221 cagcattcca accgccccca acgtcccagg caccattatc aacaggtcct acctgcatga
     5281 tgcaaccgtt cccaacaatg tgcgagaaaa aacctaattc tgggtctttc cgccagtgat
     5341 aatccgcttc attctgtacg gttgaatgcg gattcccagt tgagtgtgcg tgtacttgcc
     5401 tatatggttg cacgccgact tgaggcaaat ctgttcttaa tttactcaca ttaatttcca
     5461 tattctactc cttatcaatt aaaacaactc attttttaca atccagaacc agaaactcct
     5521 ttatttctac cttacaaaga agacaatctt agtcacgatt aggcttgtag atagaacctc
     5581 aaaacgcact attttgacac tgtaaatagg actgacaagg tctgcattct atctacaata
     5641 acaccccaga ctaaaaagct tttcaaaagt atatttttac agtctctata tgtccttttc
     5701 ataaatacta tactttatta tatcatataa aagaagtcaa aagtctgtta aactattttc
     5761 aacaccaaac taaagaagag aacacaagtt ttttcgatgt tcactagagg aaatggattt
     5821 tattcagtaa atccaactag gattgcactt tggttgccaa aattgccttt ccttctttta
     5881 tcaagggatg acggaatagt gagaagtaca gttgaactgt catggcaacc cagataagag
     5941 gttcacaaag gataacaccc ttatatcctg cccaaggaat aatcaaaacc acaaaaacga
     6001 tttttccgat tagttcaata aagctagaaa ctagaggaag gatcttctgc cccaagccct
     6061 gcaagcaatt gcgataaatc aacaagaggc tcaaaatggg ataaaaggct gaactgattt
     6121 gcagatagag acttccattt tctatcaagt aaccatctgt cgaactagcc aagaaggaaa
     6181 ccaaggctgg actggcaaaa aagaggaaaa tacaaacaaa aactgcccag gatatactta
     6241 aacgactgcc gattcgaaga ccttgaacaa tgcggtcagg tcgcttagct cctagattct
     6301 gagaagcaaa ggtcgtcatt gatgcagaaa tagcggtcat aggaagaagg gcaaaggtca
     6361 taatgcgtcg agctgccgtc tgggcactaa taatcactgc accaaatgta ttaacagaaa
     6421 actgtaaaat cacactgccg atagatacaa ttgaactcat caagcccata gccaaacctt
     6481 gctccaagag atccgcgtac aagcttttgt cccatttgaa atgtttaaac cgtggcaaga
     6541 gttctggcac acttttacga atataataaa agcagagaac cgctgataaa ccttgcgaaa
     6601 taatggtagc aagtcctgcg gattgaactc ccagatgcaa ttgcgtaata aaatagagat
     6661 ccagaaccac attaaccaag gcagagaaaa tcagaaatcc cagggctgct agactgtcac
     6721 caatagaccg caacaagcct gcaaaaagat tataagcaaa gctgacacct acacaggtca
     6781 caatcataga aatatattga taagattgag gaagaatttc tgcaggagta tctaagtatt
     6841 gcaagagagg atacaagcca agaaagccca gcaacataac tagaatgctc aaaagagcac
     6901 ctaaaatcca ggtggctgct actgcttcct tgattttagt gaaattccga gccccataat
     6961 aacgagcaat gacaatcccc atgccattgc caacaccaag tgtaaaacct acaatcaggt
     7021 caaaaatcgc tgtcgtcgct cctactgcag ccaaggattc ttgaccaaga aatcgtccaa
     7081 caatcaagac atcagcagtg ttatagagct gttgaaaaat atttgatagc aagattggaa
     7141 aggtgaagct taagagcgag ggaagaatcg aaccatgtat caggtccact gttcgttttt
     7201 tattcataaa gctattatat cagctttcca gaggagcgac aagaaacagc aaacttatat
     7261 atagcggaat gaaataagga cagtcaaatc gatttttaac aatgttttag aaatagatgt
     7321 gtactattct agtttcgatc tattatagtt ggttgagttt ggaatagtac gctgtagctg
     7381 ctaaaacatt tctagaaatt aatttgactt tcctaataaa gttgttcata tcttatttca
     7441 agctactata tataatctaa aaacttgaat caaaaatcga aaaagtagcg gatttttcca
     7501 ctgctttaac agcttattct tcaatttcga tttcaagttc atcgcctaag tcaagcgtaa
     7561 cttcttcatt cactgcttct tctttctttg gctcatcttt tttgttttca gtatcttgtt
     7621 ctgaaacttc ttctccatca atcaagccaa atttagaacg gacttgctta tcaatttcat
     7681 caaagatttc tgggtgctct gccaagtatt tcttagcatt ctcagaacct tgcccaattt
     7741 tttcatcttt gtaagaatac caagcccctg cttttttgat aatatccaaa tcgcttgcaa
     7801 tcttcaaaag ctcaccagtc ttagaaattc cttctccgta cataatttca actacggctt
     7861 ccttaaacgg tggagctacc ttatttttta caaccttaat cttagtttct ttaccgacat
     7921 tggtttcttt ttggtcacca gttcccttaa tttgtgtatt accacgaaca tccaagcgga
     7981 ctgaagcata gaatttcaaa gcacgtccgc ccggtgttgt ttctggattt ccaaacatca
     8041 ctccaacttt ttcacgcaat tggttgataa aaatggcaat tgttttggtt ttattgatag
     8101 aggcgccaag tttacgcatg gcctggctca tcatacgagc ctgcaaacca acatggctat
     8161 ctccgatatc tccatcaatt tccgcacgag gaacaagggc agcaactgag tcgactacga
     8221 caagatcaac tgcacctgag tcaatcaatt ttcccgcaat ttcaagacct tgctctcctg
     8281 agtctggttg agacaagagc aattcgtcaa tattgacacc aagggccgca gcataagctg
     8341 gatcaagggc atgttccgca tcgataaagg cagcaatccc accttctttt tgcgcttgtg
     8401 caactgcatg aagggcaacc gttgtcttac cagatgactc tgggccatag atttcgatga
     8461 tacgtccctt aggataacca cctgagccaa gggcaatgtc aagagctaaa gaacctgagc
     8521 tcatcacttg caccttttgc tccgcacgtt cacccaaacg catgattgat cctttaccaa
     8581 agtctttctc aatcaattta agagcgtcat tcaaggcctt ttcacgttct gccccaaatt
     8641 tttttgaaat ttcttctaat ttttttggtt ttttcgccat tctattctcc tacattctaa
     8701 tgatcctcag acctatctac tattatatca aaagttagtc acttaataaa gccttgcgaa
     8761 ctaggttaaa ggcatgcata accgcaatat gacgtacatc tgctcggctt ctgcctccaa
     8821 tattaacctt gataacctca gttccttgct cttgcgccaa gcctatgaag actgtcccaa
     8881 ctgggtgtcc ttctaggcta tctggtcctg ccactccggt caaactaatt ccaaaatcag
     8941 actgggtctt gcttcgtgcc tgctcagcca tcttctgagc tgtaaattca gacaccacac
     9001 catgttcttc caaattcttg gcaggaatat ccaacatcct tgatttttcc tccaagctat
     9061 aggtcacaaa accaccctta aatatacttg aaactccaga aaaattcgcc acggtagctt
     9121 ggaaaagacc tgccgtcaaa ctctctgcag ccgcgatggt tttcccttgc cttttcagtt
     9181 cttctaccac aatgctggct aaactagttt cttccccata accatagcaa aagtctcgta
     9241 aagaaattcc ttcgaaagtc tggcagtcca agatttgatt ttccaagata tccagcgctt
     9301 gattcgcctc ttcttgactg ctagcctttg ttgacagacg tagagtgact tctcctgtct
     9361 tggcataagg ggccaaggta ggatcgatct gattatcaat taaatcagcc aaaatcgtaa
     9421 ccagctggct ctcgccaatc ccaaagaaac gaagaactcg ggaatacagc ttgctccctg
     9481 tcatcaactt gggtagaagt tggtttaaga ccatgggttt caattcactt ggcggacctg
     9541 gaaggacgac ataggtcact ccgtctactt ctaattttcc tccaacagcc agtcctgttt
     9601 cgtttggcag tggaatcgct ccttctacaa tttgagcttg tctttcgtta ttcggtgttc
     9661 gggcatagtc tggtcgcagg gcaaaaaaga tatccaactt ctcctgagcc tgaggatcaa
     9721 agactaatgc tttccctaaa aatttagcta gggtttgttt ggttaggtcg tcctcagttg
     9781 gccccaaacc gcctgtcaaa atcaccagac tgctacgttg actggcaatc tcaagcaaag
     9841 acaagagacg aacttcattg tctcctacag ccgtctgaaa atatacatct accccaatct
     9901 cagctagttt ttccgacaaa aactgggcat tggtgttgac aatctgtcct gtcaaaatct
     9961 ctgttccaac agcaatgatt tctgctttca tgtttcctcc tacctatcta ttcgtatttt
    10021 tttgaaaaaa tcgcaggaat tttcctacga ttgatttttt tatttgtatc aaaagttaat
    10081 tatcttcatc accaacaggt gctctgccaa ataaatcttc aaataaaacc gcattggttt
    10141 caagctgagt aacttcttct tgtcccaaag aacgtcggag tatattttgc atttccaaca
    10201 tatgtgctct cgaaacaatc tggtaagaaa caccttgaag tatctctcct tcaccctgca
    10261 actgctgagt ttcaatggtt ttaaatgaat ctttatagcc tagcaagtta gggatacttt
    10321 ttgcagacaa atcaatattg gtctgcatat tgtcactcaa agcttttaga atctcttgat
    10381 aatgaccaat gctatttaaa ctgagagctt tttccatgac tttttgaata acttcacgtt
    10441 gacgtttttg acgaccataa tccccctcag gatcttggta acgcattcgt gcatagacta
    10501 gggcttcttc tcccccaata tgttgctccc caacaccgat agaaatggta ttaaattctt
    10561 cttggtcact gatagaaatt gggaaaccta ggatattatt gactgtaata cctcctactg
    10621 catccactaa tttttgcaac cctctcatat tgaccatcac atagcgatca atatggatat
    10681 tcatcatttt ttgaatggtt tctatagcaa gctctgctcc accatctgca tatgctgagt
    10741 tcagtttcgc ttcatgagcc tgaccattcc ctgattcaat gcgcgtcaga atatcccgct
    10801 ctaaactcat cattgttgtt tttttcgttt taggattcac tgtcatcaag atcatgctat
    10861 cacttctacc gacccaagtt tcagttcgtt caacatttcc ggtgtccact cccattaaca
    10921 gaatggttag aggttcagtc gcttcaataa ccttggtttc ttcgccgatt tttttatagg
    10981 ttttagctaa ggtttctgtc ccttgttgat aaatagtata agcaaaaaca cctactccta
    11041 ctacagttac agaaagtaaa gctagcacca ttccaataat ttttttaacc atatttctac
    11101 taacctatca gtttacccat caagtaaaca tcgataaatt tcccttcttc tatatatgcc
    11161 ccacgctctt ggctaccttc aatgacaaag ccatgctttt gataaagatg gactgctgct
    11221 tgattacgag tttggacagt cagttggaga cgacgcagaa tgccacttgc ttgtgcccac
    11281 tctatcgctt cttctagcaa caaacttccc aagccattat tccaatatct ttttccaatc
    11341 acaatgaaga gatctccaat atgacggact ctcttacgct gatcagctgt aatatttaca
    11401 ataccagtaa ttttgccatt taagaatgca agtaaggtta tctgattgtc cgaactagct
    11461 tgcttgttga ggaatatttc catctcctca ctagtcaaga gaataccatc tccgtctagg
    11521 ctggtaaagt ctgtctccaa actcacacga tttaaaaagg ccactaattc agctgcatct
    11581 ttgggctctg cttccctaat gagcaattca tactccatat tgaagctcct ctgacaattt
    11641 ctcagcacgc aaaccctttg cctgaaaatt taaacggcgt ccatctgctt cttttagaat
    11701 ttccaattct aaataagcat ctggcaaggc atctcctaag agatttcccc actcaataac
    11761 agtcacgccg ccaccaaaga taaactcatc caagtcgata gaatcagcat ctccttcaat
    11821 acgataaaca tctaggtgat aaagtggaag tcgaccttca tactctctca cgatagtata
    11881 ggtaggactt ttaatcattt gagaaatctg taatcctttt gcaagtcctt tagtaaaggt
    11941 cgttttacct gcacccagtt ctccaattaa gattaaaaca tcattctttg ctaatagatg
    12001 gcccaaacgc tcccctaagg cttgcaactc ttcttcattt tttatgtaca tactcttatt
    12061 ataccaaaaa cttttctttt gtgtctattt tcctactaaa cttatcatca taacatccat
    12121 aaaaaacagg ctttctctaa aagaaaatga gcgtaacaat gaccaataca agatctcgga
    12181 aaatatgacc ataaaaggaa acttccttct taaccgaatt tgggacaaga taggctgcaa
    12241 aaaacaagcc cagtccaata taaatcagaa gtgagacaat ggtcattgga tttcttaaga
    12301 aaagaagtgt tgctaaaata gtcaccaaca ctgtcttttt tctgtccagc atagcaagaa
    12361 aatcgcgcac gtattttttc aagggtaaaa aaatcagcaa atctagccca aataggaaaa
    12421 agaaggatgg caataaaaag tcaactaatt cttgctgcag cgtatttttg atgaacaagt
    12481 tatctgacaa aacaagaaca gctcctaaca aattaattaa gagtaacata ctgtaaaaaa
    12541 gcttcaccga cttcttactg gctaggacac tatggacttc ttgcttacga gtataaagat
    12601 aatttactcc agcacagatt cctgaaacga aaaccatgct tccgatgaaa aaagctgtac
    12661 tttgtttaaa ggacaagatg cattccttcc ataggaaaca gctactcaaa ctgatttgaa
    12721 ttaaagctaa caaaaataag attctcattg atttcatctt ctctctccct tcctaccaat
    12781 cattatacta ggagaaaaga gagaactgtt tctaatcttc tcaaatgtct ctttaagacg
    12841 ctaaacaaac actagagact aatactcaat gaaaatcaaa gagcaaacta ggtagctagc
    12901 cacaggttgc tcaaaacact gttttgagat tgcagataga gctgacgtgg tttgaagaga
    12961 tttacgaaga atataaattt gaaatcatga aaatccgtca aacgggtggt tgttttgtct
    13021 cgcacctcac ggagcgagac ggactcagag tcacataatt ataaggctga tagtattaat
    13081 ctaactatca gccttacagg ttatttaacg tttcagaaaa actataatgt caagattaac
    13141 taaacagtat ctagttcctt caaataattt tctatcttca tcaacattaa aggattgtta
    13201 taaatcttac ataactctct tgcttctata taataatttt tgacttgttc tctgtctaga
    13261 aatttggctc cagcatttcc tacaagaata agtagaggag ccaattggta gcttgtctgt
    13321 ctttgtttac agagttcaat cgtttcaaga gcttcttgga tggcttcatt atatttttcc
    13381 tttgatacta ggtagtgagc gtagttgtaa cgaactctga tgtagccaaa taaaaactct
    13441 tgatggtcca aattttttgt ctgatacaac tctattaaat gagagtagtt tgcctcatat
    13501 tcttgttcac gacccactaa ggaatagaaa ttagatagag tattcaacgc ctttaaataa
    13561 atcagagtat ttgaagagac ttttaataat atattttcca atgaagaaat tgcctcacac
    13621 ttactgtcat attgatagaa gtcaataata gctttaatcc attcaaggta agttcggtct
    13681 tctagtgtta gaaaagtact tcgttcaatc tctattctat aaatatattc caaatcgtca
    13741 taatttctat cgtctaatag tcgagcagac aattgcttga aattagagag gttagattta
    13801 atttcaattt gttcattaaa aaaataatct aatggtactt caagtcgttg agagagtttg
    13861 aacaaaaggt ctgcggaggg aatgaaatgc cctctctcaa ttttactaat ctgactttgt
    13921 tcacaaattc cttctgcaag agtttgttgg gagagtctca actcttttct tttcaatctg
    13981 aatttctctg cgagtgtatt cattaaagat aataaacctt cctatttgct taattgcatt
    14041 ataaaatttt tagttcaaaa tagcaagtta aaagaataaa taattcttta tggtaataaa
    14101 ctaaaaaaag tcaaaaatta cataaaaatg cttgaccgaa taatatatat atattaaaat
    14161 aaaaacaagg aaaaagaaaa gggtttcacg aatgaagaaa aatcgtggaa ttcaaaaatt
    14221 agctatatta gtattactag gtgtttttat gcttagtaac acaattcctt accaacagtt
    14281 tattcagaag aatagacaat tggagattcg agtccaatca caaaagaagt ccaatggtct
    14341 tgatgttggg aaggctgatt gatttcgtat tactttaaaa ttcaactatt tagagaaagg
    14401 tattctgatg agagcttgta acaataccag atagatatta gtaagcttgt tagtttatag
    14461 agggcagggg tatttctgcc ctctgtttta gaataaggaa tgcactatga aaaaattatt
    14521 tatactcata tccaacctgc ttgctagttt gttctttgtt tgggtattta ccatttggac
    14581 tgatacatat gtctcctatt attaccccaa cgttgttgta catgattctt cccctgaaac
    14641 aacttttcag catgttgcta cacgcttgga aaaactagca gaagaaacag atagctttat
    14701 tgcgattcaa caccaagatt ctaactcaga aggtactaca gttttttctt atacgacctt
    14761 tggggacgga aagttgcctg atgggcttca ggaaaaaaaa ctagaagatg ctcaaagtag
    14821 tagtgttgaa acaaactatt ttgtattcga tggacaccta gatattcact tgctaaggga
    14881 ggagctaagt caacttggct tgactaacat gaacctgaca attccatcta aactatctac
    14941 gttaatggct atctttagta acggatttca gttaatcagt ctattgattt tcatcttaac
    15001 ctttgtagca ctgactttaa ttagtcaaat tagccaatta cggtcgtcgg gcattcgcct
    15061 catttcagga gagaaacggt ggtccatttt ccttagacca gttggtgagg atttgaaagg
    15121 gatagctgtt ggtttcagtt tagctggcgt gctcgccatt cttatgcaaa aaattctgtc
    15181 gcttccaacg caatccctaa tgaccatagg agcaggcttg ctcagttata atctcatctt
    15241 gttgtcgatc tccctgtttt tcgctcaact cttcgcagtt gggataaaaa agatacacct
    15301 gatgcagatt ataaaagggc aagtgcctgt cagaggaatc attagtttga ttttaatcgg
    15361 tcaactatta gcgattatta ttgtaacgct gggaataggg agtagcttaa agtattccca
    15421 agcctggcaa cagcatcgga ttggacaaga ggcttggagt caggaaaggc aactgattac
    15481 cctatcaatc agccgtgaag gaacgagtcc tggttttgat gaacaagctc aaaggaaact
    15541 cagaacttgg tatcaattga tggatctggc tgtttcagaa caaaaggctt tcttatctag
    15601 acaccagtta attgaccgta ctttgcaaaa tggcatggct tcctccaaaa acttgataac
    15661 ctctacagaa tggcacgatt acaacccgaa tggcaatgtc cttatcgtca caccgcaata
    15721 cttggagcgt caaaacattc ctgtagatac aactattgag caaaagatga atcaccttta
    15781 tgtaggggag tttgtcttat tgctgcctga acacctccgt tcagaggaag aacattataa
    15841 atctgttttt gaagacgact taaccagtcg catgtctagt caagatgaac gacagcaaat
    15901 gactgctacg gtaggttatt tagaatcagg tcaggatcgt tttgtgtata atacgacccc
    15961 tatttcttac cagcagtttt tgaaagatcc aatcatcatt gttataacac cccaatcaac
    16021 tggtccacag tccattttgt tttggataga cgcagtacag aactacgttc tctttaatca
    16081 attgtctgat gcccaggagc ttatccagag acaaggcatt gaaaattggg tctcagaaat
    16141 gcaaacaggt taccacaact acatcacatt attggataat attcagaggg aacgttgggt
    16201 aatgctagca ggagctgggc ttgggattgc aacttcaatc ttgttgttta acactatgaa
    16261 taggctctac tttgaagaat ttagacgtgc catttttatc aaacgcattg caggtctcag
    16321 gttcttagaa atccatcgca cttatctctt tgctcaactg ggtgtgtttt tactgggatt
    16381 tgttgcgagt gtatttcttc aggtagagat aggagttgct ttcttagtct tgttactctt
    16441 tactggtcta tctcttttac agttacatgt ccaaatgcag aaagaaaaca agatgtccat
    16501 gcttgttttg aagggaggtt aatatgattg aacttaaaca ggtgagtaaa tcttttggag
    16561 aacgagagtt attttcgaat ctttcaatga catttgaggc tggaaaagtc tatgccttaa
    16621 ttggttcaag tggtagcgga aaaacaacct tgatgaacat gattgggaaa ttagaacctt
    16681 atgatgggac gattttttac cgaggtaaag acttggccaa ttataaatcg agtgattttt
    16741 tccgtcacga attgggctac ctcttccaga actttggctt aattgaaaac caaagtattg
    16801 aagaaaacct taagctaggt ctcattggtc aaaagttgag tcggtcggaa cagcggttga
    16861 ggcagaagca ggctttagaa caggtcggcc tgacttatct tgacctagat aagcgcatct
    16921 ttgagttatc gggcggagaa tcgcaacggg ttgccttggc aaaagttatc ttaaagaatc
    16981 caccctttat tctggcagat gagccaacag cttcaataga cccagcaact tctcagttga
    17041 ttatggagat tttgctatct cttcgagatg ataataggct aatcattatc gcaacacata
    17101 atccagcaat ttgggagatg gctgatgaag tgttcacgat ggatcgtctg aaataaaaat
    17161 ccttgttttt aattgcacga tgagttactg aaatattatc atgaatcaat aattggagtt
    17221 aatttagaat tgtactttat taatattgag gtaacttttt cttgataaag gaagaaatag
    17281 tggagaggaa gttagaatga aaaaattcga caattatatt gttgagaagc cttgcgattc
    17341 taattcagat aaactgcaaa aaatcttaat aattgaaaat ttggtagatg atattttgca
    17401 atttcctctc agaatcaata atagtgtagg agagattttc ctcctacaac cgtttcaaaa
    17461 gaaaactatc tttattccat gttattttga ggaagatatt gtgaaagtca aagatgatga
    17521 taaagttgag tggaatttgt tagaatttca aaaatttaga gcatttttgg cttagtaatc
    17581 tgtgttgaag gctcaaaacc tatggtaaaa aagtcgcttt gaaaacgtat tgcctccaaa
    17641 gatttagtta aataatgatt taacacaaaa agaaattatt gaagttctgg aaagatgttg
    17701 tttcagtatt gagaaaaggt gggaaaaact tgcgattttc acagagaaag gaagaaaaag
    17761 tatagaaata tagtcaattg aaacaagaac aggacaaaag aaccttttgt gccatatttt
    17821 tctcctttcg ctttacaatt ggcttgaaca cctttattgt atcgcgtttg gagttttttt
    17881 ggtataacct tcgacgcgca cccgcatagc gggtgttttt ttgtctcgca cctaacggag
    17941 cgagacgaac taatagtcac ttaatcaaaa aacgcaccat atcaaaaact aaaaagtttg
    18001 atatcatgcg tcatgtctta aactaattga ctatactttc tattcaaatg agcttttaac
    18061 caattgattg agccaatcca ctcttaaaac caaagagcaa tttctcgctt agctgactct
    18121 tctgaatctg aaccatgtac aacattttgg ataacctcat tttctccagc agcttttgca
    18181 aaatcacctc gaatagtgcc tggtaaagct tcttctggac gagttgcacc catcatggtc
    18241 cgccaagttt cgattacttt gggaccagaa atgacaccca caagaactgg acctgaagtc
    18301 atgaattcac gaatcggtgg gtaaaaactc tgaccaacca agtcctgata gtgctggtca
    18361 atcaactctt ctgaaacttg tgaacgaaac tccaattttt cgattgtaaa tccacgttgt
    18421 tcgatgcgct ttaacacttc acccactagc cctcttttta caccatctgg tttgatgata
    18481 aagaatgttt gttccatacc cgtctccttt gtcagcttct ttcttttatt ttaccacatt
    18541 tcgtggaaaa atggagaaag ttttcagaat agagaatgag agaacccgag ggttctctca
    18601 ttctctatta ttctactgtt tcttccacag tttcaacggc agtatccaca actacttctg
    18661 ttgtttcttc atttccttct tcctctactg gaggattaag gtattcttct tcgttgacag
    18721 catatggttc aaggttacgg taacgggcca taccagtacc agctgggatg agcttaccga
    18781 tgataacatt ttctttaagt ccaaggagat ggtctttctt accacggata gctgcgtcag
    18841 taaggacacg agttgtttcc tggaaggaag ccgctgacaa gaaactgttt gtttcaagtg
    18901 aggctttggt aattcccata aggactgggc gacctgtcgc tggaactcca cctgcgataa
    18961 ggacatcttt gttggcatct gtaaagtcat tgatatccat gagggtaccc atgagaagat
    19021 ctgtatcacc tggatccatg acacggactt tacggatcat ttgacgaacc attacctcga
    19081 tgtgtttgtc accgatttct accccttggc tacggtaaac tttttgtact tcaccgagaa
    19141 ggtacgtttc aactgacaag acatcacgaa ctgcaaggag acgttttggt tggatagaac
    19201 cttctgtcag agcagcacca cgcgctactt ggcccccaac ttcgacacgc atacgagctg
    19261 taaatggaac gacatattca ccttcgccag tttcaccctt aacaaagact ttcttggtac
    19321 gagttgatgc atcttcttcg atagcagtaa cttgtccttt aacctctgtg ataaccgctt
    19381 cccctttagg attgcgggct tcaaagattt cttggacacg aggaagaccc tgagtgatat
    19441 cggtatttga ggcaacccca cctgtgtgga aggtacgcat tgtaagctgt gtaccaggtt
    19501 ccccgataga ttgggcagca atggtaccaa ctgcttcacc aacttcaacc gcatcaccag
    19561 tcgccaagtt gataccgtaa cagtgacggc agacaccgtg acgagtgtta catgtaaata
    19621 cagaacggat agtcacttct tccacaccag cattgacaat ttcacgcgcc ttgtcttctg
    19681 taatcaattc atttggacca ataatcactg caccagtttc tggatgttta acagttttct
    19741 tagtgtaacg accgttgaga cgctcttcga gagactcgat catctctttt ccttctgcga
    19801 tagaacggat caagagacca cggtcagttc cacagtcgtc ctcacggatg ataacgtctt
    19861 gggcaacgtc gaccaaacga cgagtcaagt aacctgagtc ggctgtctta agggccgtat
    19921 cggtcatacc tttacgagca ccgtgagttg agaagaacat ttccaatacc gacaaacctt
    19981 cgcggaagtt tgaaaggatt ggcaattcca tgatacgtcc attcggagca gccatcagac
    20041 cacgcatacc ggcaagctgt gagaagtttg agatgttacc acgggctcca gagtccatca
    20101 tcataacgat tgggttctta ggatcttggt tagcaatcaa gcgtttctca agtttttcac
    20161 gggcagcacg ccattcagct gtaacagcat tgtaacgctc gtcgtctgtg atcataccac
    20221 gacggaattg tttggtgatt tgttcgacac gtttgtgtga ttcttcaatg atttcagtct
    20281 tgtcatcaac gactgggata tcggcaatac ccactgtcaa tcctgcaaga gttgagtggt
    20341 ggtaaccgag gttcttcatg cggtcaagta gggcagaagt ttctgtcgta cggaaacgtt
    20401 tgaagatttc agcgatgata tttccaaggt ttttcttctt gaatggaggg ttgagctcaa
    20461 gattgctgat agcttccttg atatctccac caagtggcaa gaagtattta gctggaacac
    20521 cttctgtcaa gttggcattg tttggttctt gcaagtatgg tagcccctct ggcatgatat
    20581 cgttgaagag aattttacca actgttgtaa gcaagacctt atgtctttgc tcttctgtcc
    20641 aaggcttgtt gaggctgtct gttgcgatac caacacgtga gtggaggtga acataaccat
    20701 tgcggtaagc cataaccgct tcgtcacggt ctttgaagac cattccttca ccttcgcgac
    20761 cagcttcttc catggtcaag tagtagttac ccaaaaccat gtcctgagat ggagtaacta
    20821 ccggtttccc atctttcggg ttcaagatgt gctcagcagc tagcatgagg atacgagctt
    20881 ctgcttgtgc ttcttctgaa agtggtacgt ggatggccat ttggtccccg tcaaagtcgg
    20941 cattgtaggc ttcacagaca agtgggtgca agcgaagagc cttaccatca attaagactg
    21001 gctcgaaggc ttggataccc aaacggtgaa gggtcggtgc gcggttcaaa agcactgggt
    21061 gttctttaat cacttcttca aggatatccc agatacgctc atctccgcgt tccaccaagc
    21121 gtttagctgc tttgacgttt tgcacgatat cacgggcaac gatttcacgc atgacaaatg
    21181 gtttaaagag ttcaatcgcc atttcacgtg gcacaccaca ttggtacatc ttaagagttg
    21241 gaccaacggc gataacggaa cgtcctgaga agtcaacacg tttaccgagc aagttttgac
    21301 ggaagcgtcc ttgtttacct ttaagcatgt ggctcaatga tttcaatgga cggctacctg
    21361 gtcctgtgat tggacgacca cgacgaccat tgtcaatcaa agcgtcaact gcttcttgaa
    21421 gcatacgttt ctcattttga acgatgatac ctggtgcatt taactcaagc aaacgagcca
    21481 aacggttgtt acggttgata acacggcggt aaaggtcatt caagtcagat gaggcaaaac
    21541 ggccaccatc caactgcaac attggacgaa gatctggtgg gataaccgga aggatgttaa
    21601 gaatcatcca ttcaggtttg tttccagact tgtaaaaggc atccaaaaca tccaaacgac
    21661 ggatggcttt gacacgtttt tgtccagtag ctgttttcaa ttcttctttg agttcagcaa
    21721 tttctttttc aagatctact tgcttcaaaa ggtcttggat ggcttccgca cccatcttgg
    21781 caacaaatga accataacca tattcgcgca agcgctctcg gtattcgcgc tctgtcatga
    21841 tagacttgtg ctcaagtggt gtatccttag gatcaatcac cacataagcc gcaaagtaga
    21901 taacttcctc gagggcacga gggctcatat caagggtcaa gcccatacgg cttggaatcc
    21961 ccttgaagta ccagatgtga gatacaggag ctttcaattc gatatgtccc atacgctcac
    22021 gacgaacttt cgtacgcgtt acttcaaccc cacagcggtc acaaacaatt cctctgtaac
    22081 gaatgcgttt gtacttacca caagcacatt cccagtcttt tgtaggacca aagatcactt
    22141 catcaaagag tccttcacgt tctggtttca aggtacgata attgattgtt tcaggttttt
    22201 tgacttctcc ataagaccat gaacggactt tacttggaga agctagggtg atttgcatac
    22261 ttttaaaacg atttacatca accactattt cttccctttc tattctaagt gaactgctta
    22321 ttcttgttca gcagcttctt ctgttgcttc cgcttttgtt gctttctcag cttcttcagc
    22381 ttcaaaggct gctttagcct cttgggctgc tttttcgcgg gctttttcaa ggtcatctac
    22441 gtggatgaca tcttcgtcca ttccttcatc caagtcgcga agttccactt cttggtcatc
    22501 ttcgtctagg acacgcatgt caagaccaag agattgcaat tctttgacaa gaactcggaa
    22561 ggattctgga acacctggtt ttggaattgg tttgcctttt gtaatagctt cataggcttt
    22621 caaacgtccg ttgatatcgt ccgacttgta agtcaagatt tcttgaagga catttgacgc
    22681 accgtaggct tcaagagccc aaacctccat ctcaccgaaa cgttgtccac caaactgagc
    22741 cttacctccg agtggttgtt gggtaacagt tgagtatggt ccgactgaac gcgcgtgcaa
    22801 tttatcatca accatgtggt ggagtttgat catgtacatg actccgacag aaacacggtt
    22861 atcaaacggt tcaccagtac gtccatcgta aaggatcgtt ttggcatcgc tatccatacc
    22921 tgcttcttta acagttgacc aaagatcttc agaacttgct ccatcaaaga ctggtgtcgc
    22981 gatgtgaata ccaagagtac gagctgccat accaaggtga agctccataa cctgaccgat
    23041 attcatacgt gatggtaccc caagtgggtt caacatgatg tcgactggag ttccgtctgg
    23101 aaggtaaggc atgtcttcta caggaacgat acgagagaca acccctttgt ttccgtgacg
    23161 tccggccatt ttatctccga ccttaatctt acgtttttga gcgatgtaaa cacgaaccaa
    23221 catgttaaca cctgattgca actcatctcc atttacacgt gtaaagatct taacatcacg
    23281 aacgacacca tcggcaccgt gtggtacacg aagagaagta tcacgcactt cacgagactt
    23341 gtctccaaag atagcgtgca agagacgttc ttcagctgaa agatctttct cacccttagg
    23401 tgttacttta cctacaagaa tatcaccttc tttaacctca gcaccaatac ggataatccc
    23461 catttcgtca aggtctttga gggcatcttc accaacgttt ggaatttcgc gagtgatttc
    23521 ttcaggccca agctttgtat cgcgcgtttc tgattcgtat tcttcaaggt gaacagatgt
    23581 gtagacatcg tccttcacca agcgttcgct catgataacg gcatcctcga agttgtaacc
    23641 ttcccaagtc atgtaggcaa cgattgggtt ttgtccaagc gccatttctc cattttccat
    23701 agaaggtccg tcagcgatga aatcgccttt ttcaacgaca tcaccaactt ttacgagagt
    23761 gcgttggttg taagcagtac ctgagtttga acgacggaat ttttggatgt ggtaaacatc
    23821 caatgaacca tcttcacgac gaacttctac cttgtcagca tctgcgtaag taactttacc
    23881 atcatactga gcaatcacag ccgcaccaga atcgtgggct gcttggtatt ccataccagt
    23941 accaacgtaa ggtgcctgag gattaatcaa tggcacagcc tgacgttgca tattggctcc
    24001 catgagggca cggttggagt catcgttttc caagaaagga atacatgctg tcgcaacggc
    24061 aactacctgt tttggtgaaa cgtccatgta gtcaacaata ttagctggat actcttggtt
    24121 gaccccttgg tgacgtccca tgacaatctt ctcagcaaag gttccatctt cattcagacg
    24181 agagttagcc tgagctacag tatattcatc ttcttcatca gctgtcaacc aaacaatttc
    24241 gttcgtgaca acacctgttt cacggtcaac cttacggtat ggtgtttgaa caaaaccata
    24301 tttgttcaag tgtccgtaag atgacaagtt attgatcaaa ccgatgttag gtccttcagg
    24361 tgtctcgatt ggacacatac gaccatagtg agtgtagtgc acgtcacgta cttcatatcc
    24421 ggcacggtca cgagtcaaac caccaggtcc taaggctgac aaacggcgtt tgtgagacaa
    24481 ctcagaaagc gggttgtgtt ggtccatgaa ctgtgacaac tgtgatgaac caaagaattc
    24541 tttaactgca gctgttacag gacggatatt gataatttgt tgtggtgtca agacttcatt
    24601 gtcctgaaca gacatacgtt cacggacatt acgttccata cgagaaagtc ccaaacgtac
    24661 ttggttggca agcaattcac caaccgcacg gatacgacga tttccaaggt ggtcgatatc
    24721 atctacacgg ccaagtcctt cagccaagtt gaggaagtag ctcatctcag caaggatatc
    24781 tgcaggagtc accgtacgaa ccttgtcatc tgggttagca ttaccaatga tcgttacgac
    24841 gcgatctgga tcagttggag caacaacctt gaatttttga agaacaacag gctcagtcac
    24901 aacggctgca tcgtttggga tgtagacaat cttgttcaag tcgccatcca aatggctttc
    24961 aatgctttca atcacgctac gagtcataat cgtaccagct tctaccaaga tttctccagt
    25021 ttcagggtct accaatggct ctgcaatggt ttggttgagc aaacgtgttt taacattgag
    25081 ttttttattg attttgtaac gaccaactgc tgccaagtca tagcgacgtg ggtcaaagaa
    25141 gcgagccaca agcaagctac gtgagctttc agccgtctta ggctcacctg gacgaaggcg
    25201 ttcgtaaatt tctttcaagg cttcgtctgt acgagagtcc attggattct tgtggatatc
    25261 tttttcaaca gtgttgcgaa ccaattcgct gtcaccaaaa atatcaaaga tttcatcatc
    25321 acctgagaaa ccaagagcac gaaccaaggt tgtaaatgga atcttacgag tacggtcgat
    25381 acgagtgtag gtgatatctt ttgagtcgct ttcaagttcc aaccaagctc cacggttagg
    25441 gataacagtt gaaccatagc ccaccttacc atttttgtct actttgtcgt taaagtaaac
    25501 acctggtgag cggaccaact gagaaacgat aatacgttca ccaccattga tgatgaaagt
    25561 acccatttct gtcatgattg ggaaatcacc aaagaaaact tcttgggtct tgatttcgcc
    25621 tgtttcttta ttgatcaagc ggaaggttac aaaaattggt gctgagtagc tagcatcgtg
    25681 aatacgagct tcttctagcg tgtattttgg ttccttgatt tcatatccaa caaattccaa
    25741 ctccattgtg tctgtgaagt ttgaaattgg caatacatct tcaaacactt ccttaagacc
    25801 gtggtctagg aaagctttga atgagtcagt ttgaatttca atcaaatttg gtaagtcaag
    25861 aacttctttg attcttgaaa aactacgacg ggtacgatgt ttcccgtatt gaacgtcatg
    25921 tcctgccaag atgattctcc tttgtaaata agttccaagc cttgtcaatc aggcttttct
    25981 aatcgccata tggttgtaaa ccccttatca ccgtgtcctc ttgacgaatt ttcagaatct
    26041 ttaagcctct gttacaaatg ctcaaaatct tgaaaaaaag cacaaaaaga gcagctaaat
    26101 ctgacttttt cagaagattt aactgctgtg agccttgtct ggacaatatt tcagacaaaa
    26161 cctacgacaa atgattaccc atattatacc ctatttagct agatttttca aggggattca
    26221 gtaggttttt ggtaattttt ttcccataga aaacttggca tcacattcga atcacgctat
    26281 ggtacaaaaa actgaaaaaa ctattgactg aaaatcattt tcaaggtata ataataaacg
    26341 ttaaggcggt atagccaagt ggtaaggcac ggctctgcaa aagcttgatc gtcggttcaa
    26401 atccgtctac cgccttctat aacttgattt atcaggtttc aaatgaacag aaagcccaat
    26461 ttgaagggct ttttttattt tccctcgaat aaatacgtat aactttaaaa acttttggag
    26521 cgagtttgtg gcagagttct ttccatggca taattccctt ttgaaatcaa ttgaaaaaag
    26581 cttcgtcacg cctggtgaca aaagcctcta gtttattctg tttcttcttc tatttcgact
    26641 tctgtgattt ggacttttac cttggtaaca cgtccattct tcactttatc attggttaag
    26701 ataaactgtt tgttttggct gaccaattca tagctgagtt tctcagtcgt tggaatggtt
    26761 cccactcctg tcaaataata accagcgatg gtatcaacgt catcactttc cagttcaaca
    26821 tcaaagtaat tattgaaatc attgagggtc atagttcctt gaacaatgta ggtatcctcg
    26881 ccaatctgat gaacatctat tgctgctttg tccgtttcat catcaatttc accaacaatt
    26941 tcctctaaga ggtcttccaa agtcaccaaa ccagccatac caccgtattc atccagcaag
    27001 attgccattt gtctttgggt atttcgcagt tcttttagca agtcatccac aaaaatagtt
    27061 tcaggtacaa aaagtggatc ttgtaaaatt ctcttccaaa caatattgtc aaaaccgtcc
    27121 acaaagcctg ccttaaggag actcttggtg tgaatgattc caattacatt gtccttatcc
    27181 ccatcataaa ccgggatacg agaataattt tgttttaaaa tactttggat aatggcttga
    27241 ctatcatcct gaatatccac cataaaggca tccgttcgag gcaccataac ctctcgtgcc
    27301 atcagttcat cgagcgaaaa gacaccttgt agcatctcaa tctcatcagc atccaatgtt
    27361 tcttcactat ttgtcagcat ataggcaatt tcatcacggg tcatcttttc atccgcatca
    27421 tcgaatgaca taggagtcaa atggctcaag aaattggtcg aagcagctaa aagccaaaca
    27481 aaaggactga ctagttttcc gatcccaatg ataatcggcg ctgtacgaat tgccaaggca
    27541 tcctttagat taagagcgat tctcttagga tataattccc caaaaacgat ggaaatatag
    27601 gtcaaaaatg ccaaggatag aaaagttgcc acggcttgtg ctgtttcgcc attcccaagc
    27661 caagaggcaa tcacacgtcc tagagtatca gttaaactcg cccctgataa gattgtaatc
    27721 agggtgattc ctacctgaat ggttgataaa aagtggttag gattttctag taccttcagc
    27781 aggcggatgt agcgtctgtc tccttcttcc gccttttgtt caactcgggc acgattaaga
    27841 gaaaccatgg ccatttctgt ggctgagaaa aaggcattta ataccgtcaa gataaacaat
    27901 aaaacaaatt gtagcaacaa attctgacta cttgggtctt ccatagttct tctcctaaaa
    27961 tagtatctta tcctttatta tatcacaaaa tttaatccaa tacatattat ttttttctta
    28021 gcgtaacttc catctctctc ccaaaactgg aagttagtct aagacggatt tccactgatt
    28081 tcacgcgttt ttctcatact aaaagctagg ttgtgggaaa ctggaagtta gttttagaag
    28141 ttactatttt ttcttagtac ctattctagc cctgcttaaa ctagtaaaaa gaactcctac
    28201 atccataagt gacataggag tttaggctta tcttttactg agttacagtt acttctccag
    28261 ttcggtaatc cagttgaagt cccttttgaa cattgggaac tagaacattg aattccaatt
    28321 ctccatccga agacttggct tcaatctgtg aagctgaggg aactaaatcc tcgtttgaag
    28381 cgtagtaaag ggttacacgg taacggacac gcttgttttg gtccaaggct ttacgcacct
    28441 tgctttcata gtagttttga ccagtcgaat actcggcttg tgcctgattt gcccaggctg
    28501 tctgaacagc aatgttttta ggattgcttg ttgaggcatc aaaaccatcc aaaccaccga
    28561 ttaaggcata gcctaacaaa tgacctctat cgactgcatg ggtataagag ccctttagat
    28621 tcttgacctg atgccaacct ggaggagtcc aagaagttga accattccca gtttctttac
    28681 gattcttgta ctgacgagtg gccttagaca agagggcatt agctacggtt ggaacagttt
    28741 ccttgcccac tgtctttgtt ttattgtcag cgtagggctt acttgaaacc ttggcatcta
    28801 gatttgtttt attaccattg acgataaaag cacctgagcc attccactcc agactcccct
    28861 ttatttgact cttgactgcg tctgttaaga cactctctgc caatgcttga ctaggagctt
    28921 cagacgcttg ttttttctga ctaagattgg ttttgggact attaggtgcc gactgcatct
    28981 gcttgatata atagctccct gtagacaaaa gcaataacac tagcagtccg attagtgtct
    29041 gtcttgtttt tttgttcata tttctcctta tctttagaaa aaggctggtt ctccagccta
    29101 atttcctgta aatttatgaa tcaattcctg ccattttgct ggagacagga tagcccatgg
    29161 atcttgaccc ttgcccaaga ttccataacc taccattaga ccgattccta gagccagagt
    29221 acctaaaatc agtactatga tgactaaaag taaacgattg attacgtagc ttgatttctt
    29281 attcatcttc atcgcttgcc tcaatccgct gaatcttagc acctagctgc gccaacttct
    29341 catggaaacc gtagtaacct ctatccaagt gaaccaattt accgaccaca gtttctccct
    29401 gtgctaccaa acctgtcaaa atcaaggctg cactggcacg aaggtcagtt gaaagaactt
    29461 ctgctccctg caaaggctgt ccaccaacaa tacgagctgt atcacggata atctcagaat
    29521 gcaagcccat gcggcgcatc tcttctaggt gttggaaacg attttcgaaa actgtctcca
    29581 ccatggttga ttcgcctttt gcaactgtca tcaaggctgt aaattgagcc tgcatatctg
    29641 ttggaaatcc tgggtggggc aaggttttca catgaacagc ttttagattt tctagttgag
    29701 aacgaacacg aattccttcg tcttcttcaa ttacttcaac acccatttca agtaacttgg
    29761 caatcaaggg acggttgtgc tcccagacag cgtctcgaat caagacatca ccaccagtca
    29821 tggcagcagc taccataaag gttcctgctt cgatacggtc ttggactaca ttgtgagtcg
    29881 taccatgaag tttctcaaca ccagtaatgg ttatagtctc tgtaccagca cctttgacct
    29941 tggctcccat ttcattaagg agaatggcta agtcaacaat ctcaggctca cgcgcagcat
    30001 tctcaatcac tgtcacccca tcagccagag tcgctgccat catcaagttc tgcgttgcac
    30061 caacacttgg aaagtccata tagatatgag cgccatgcaa gcgttctgcc ttggcttcga
    30121 tgtaaccagc tgtctgacta atcttaaccc ccatagcttc cagacctttc aaatgaagat
    30181 caataggacg gctaccaatc gtacaaccac ctggcatgga taccttggca tgacccacac
    30241 gggcaaggat tggccctaat acaacgatgg aggcgcgcat cttgctgaca tacttgtaag
    30301 gggcttcctc agtgatgtcg ccagtagcat ccaccttgac aagatgagct tcctcatcaa
    30361 agtcaacctt ggcattcaaa ccaccaacta cctgattcat aataaagaca tccgacaaaa
    30421 tcggaacatt ctgcaagacg gtctttcctt cacttgctag aatagtcgct gccaacaagg
    30481 gtaagactgc attttttgct ccctcgatcg tcacgcttcc taccagacga ttatcgccac
    30541 cttgaaccac aattttatcc atactcgttt cctttactct tgattttata ataatcctct
    30601 aagcgcttct tgccacaaat gatacaggct aataaagaaa gaactcagga tgtagcctat
    30661 gacaatgcta aaaaaggcta ctaataaacg aacttttctt gtattatcat ctgtcacttt
    30721 taaaaccttc tcccatctaa caagatcctt taaaaggtaa aaactcacat aaataaagag
    30781 catatgacta cttagagtga ataataattg aaccatttga ctattatacc atcttctctg
    30841 tttgtgcgct agtttggaaa cttcactcaa aaattaggga ttgtttttca agtaatcaat
    30901 cgcatcttgt agggttttaa cgggcacgat tttcatatcc gtcttgattg ttttagccgc
    30961 ttctagggct gtttggtagt tgtttttcgc gtccagatgc gccttttgtt cttcttcgct
    31021 aacagggtta tcaggagcaa agaaaatagc agcacctgcc ctagccgaag ctacaacctt
    31081 cttatcaata cctccaatgt ctcccacatt accatcgcgg tcaatggtac ctgtaccggc
    31141 aacaatacga ccattacgaa gatctgggtg agctatttga gtatagatag ctagactaaa
    31201 catgagacca gcacttgggc cgccaatacc agctgttgaa aagctaattg ggacattgct
    31261 gattacctct gtacggtcaa tcaagccgat tccaattcca tttttgccat tttccaaggt
    31321 gataatcttt ccttctgcag acttggtttg cccatcctct tcataggtga ccttgacgga
    31381 atcccctaat ttttgagaac tgacgtaatc aatcaagtct ttggaactat caaaggtctg
    31441 atcattgact gctgtgactg tatcagagat attgagaatc cctttaaagg ttgaattatc
    31501 cgtcacattc aaaacataaa ctccaaagta cttgagttcg atatccttac cagctgtttt
    31561 tagtccttga tacttggcca tattttgcga tgtttgcatg tagaattgat tgattcgcat
    31621 aaattcaaca tcggaagaac cacctgtagt ctcctgagca ctacgaatat ctgtaaaagg
    31681 tgtcaaccaa gcataaatca tatgagctaa agtggcatgt tgaacaccaa ccgtaacgaa
    31741 ttgataggca ccagcttcct tatcttctgt gtcatttact ttaaggactt ggcgaatatc
    31801 ttccgaacca cctggaacct ctatataata aggcaagggc actacaaatg ccaagaaagt
    31861 cacaatcaag gccgcaatga cgtataaggg ccatctaatc ttttttttca tttcttattt
    31921 cctccaaaat actctcggga acatggcagg caatatcctg accaaacttc aaaagctctc
    31981 gaacacctga tgaactgata tagagatgtt caggccggct atgtaaataa atagtctcta
    32041 tatcagaaga cagctgatga ttgtagtaat caaaactagc ttcatattgc aaatccgccg
    32101 cattcctcaa cccccgtact aggaaagtag cccccagtct ttttgcaaca tcgaccacca
    32161 attcatcatg agaagccacg acttcaacat tttccaaatg tcccaaagcc ttttctagcc
    32221 cccgtttacg attttcaaga gggagaaatc cttgtttgtg gggattaaaa aaaataccca
    32281 cataaagctt atcaaaaagt ctgctcgccc gttcaatgat atccagatgc ccatttgtca
    32341 tcggatcaaa tgagcctgtg aataagccaa tcttatctga catagactgt caccttacta
    32401 attccataaa tcttttcctt ccagataccc agacaggcaa tctcttctgg aagttcaacg
    32461 gccttatccg tctcgcacac aaccataaca tcttcagaaa aaagctctct cttagccatt
    32521 ttttcaatat ctgctacgat ttgttccttg gcatagggag ggtctaagaa aacgaggtca
    32581 aattccccag atacctgttc caatgccctc tctgcatcca tcttgaggag ttgaaatttt
    32641 ccaacttcct tggtcatctg gatattttca gccacgatgg tctgagcctt acggtctcgc
    32701 tccaccaaaa cagcactgga catgccacgc gatactgctt cgatagataa accaccacta
    32761 cctgcataaa ggtccaagac tcgtccccct tcaaagtagg gaccaatcat gttaaaaatg
    32821 gctcccctaa ccttatccga agtaggtctt gttgtcttgc cttctagtgt cttgagggga
    32881 cgtcccccat agattcctga tacgattttc atactgttta ttataccaaa ttatagacaa
    32941 aaagagaaag aaaaccgaac cttgcggttc gattctctac aaaatatttt cgtaagtatc
    33001 gcggacttct tgaggccaaa cacttgtttg cacttctccg atgtgtctct tgcgaagtag
    33061 gaacatggcc atacgagatt gtccaattcc tccaccgatt gtcaatggga ataggccatt
    33121 caacaaagac ttgtgccatt ccaattccaa gcggtcttca tcacctgtaa tttccacctg
    33181 acgtctaaga gtttcttcat ctacacgaat tcccatagaa gacaactcaa aggctccacc
    33241 taaagactca ttccagacaa gaatatcacc atttagaccc ttgtagccat tctcagactc
    33301 gcttgtccag tcatcatagt ctggtgcacg tccatcgtgc ggtttaccat ctggcaactc
    33361 gccaccgata ccaatcaaaa agacggctcc aaattcttta caaatcgcat tttcacgttc
    33421 tttcggtgtc aagtctgggt agcgttctac caattcttct gtatggataa aggtgatttg
    33481 ctttggcaag atagactcga tgtcatagcg agcttcaaca gctagctcag tcaggcgaat
    33541 agccttataa atcttctcaa ctgtttcttt tagataaacg atgttacgct taccatttgg
    33601 gataaccttc tcccagtccc actggtcaac ataaacagag tgggttgcat ccaaggaatc
    33661 ctcatctgga cgaagggctt tcatgtggac aaagagaccc tctccttcac caaagccaaa
    33721 acgagccaag gtgtggcgtt tccatttagc aagtgagtgc accacttcat aagtagcatc
    33781 agggatttgg agaaccttga ccgatactgg attttccaca ccagacaggt tgtcctgcat
    33841 tccgtcaccg accttactca agataggacc ttgaacttcg acaacttcta gcttatcttt
    33901 caaatactgg gtaaaagtgt ttttgacaaa ggaaatttct tcttgttgat ggataaaact
    33961 tttcttcata gacaactcct caaaaattta ataaacgtat tatacaccta tttccaagaa
    34021 aagaaaagag aaaatttaaa aaaatcagtg tcactcaaaa cactgatttc atagaccttt
    34081 tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa atcaagatag
    34141 atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga ttgttcatag
    34201 gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa aaccatggct
    34261 acgctaatca tataatcaaa gaagccacta gccaagaaaa tattgactac catagcaatc
    34321 agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc tttcttggta
    34381 aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa ggcagataaa
    34441 actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt taaaacggag
    34501 taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct actggcaacg
    34561 aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc ctgcatcaac
    34621 aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa agcagatagt
    34681 ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag acctgcacgg
    34741 tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt tccttgatta
    34801 taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg caactgcaac
    34861 attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg cactttcagc
    34921 cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat tttctataga
    34981 aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca ctgggatagc
    35041 taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg gcagatggaa
    35101 atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg acttatctga
    35161 aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc ctacattacc
    35221 gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag cttgtcctac
    35281 ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg ccaaatctag
    35341 caaaatatcc tctgacaccc agacagtttg cgaaaaagta gctaactgat ctcgataatt
    35401 ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt caaacaagtg
    35461 ccagccttca atcaaatagg cagacttgcg gtattttttt tggcgtaatt tcttggcatt
    35521 ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat aacacaatca
    35581 aagggggttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca gggagtcggc
    35641 tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg tcgagtatgg
    35701 aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc tatcatggca
    35761 aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag ctacttagat
    35821 gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta ggtctccaga
    35881 actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt aaagaaggaa
    35941 taaaaacagt gaaatctatt aaacgttttg cattctcggc tatgggagtg gctatgttgc
    36001 ttgtcttgac tggctgtgtc aatgtcgata aaaccacagg tcagccaaca ggatttattt
    36061 ggaatacgat cggagcgcct atggctgaag ccatcaagta cttcgctact gataaaggtc
    36121 taggctttgg tgtcgctatc attatcgtaa ccattatcgt acgcttgatt atcttaccac
    36181 ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac gctctcaagc
    36241 atgtccttga gccacaccaa acacgtctca aagaagcaac tactcaagaa gaaaaactcg
    36301 aagcccaaca agccctcttt gccgctcaaa aagagcacgg catcagcatg tttggtggtg
    36361 taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac tttgctgccc
    36421 aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt tctccaagta
    36481 tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt tcacttcacg
    36541 gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg agcccactca
    36601 tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg gttgtcggtg
    36661 gtttcatgat gattctccaa cagtttatcg tcaactatat cgttcgtcca aaacttcgca
    36721 aaaaagtccg tgaagaacta gccaagaacc caccaaaagc aagtgctttc tctaaaccaa
    36781 gtggacgaaa agacgttacc cctgaacaac caactgctat cacaagcaag aaaaaacaca
    36841 aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta gctgatttgc
    36901 taagtctttt tgcaaatcaa aagcccgatg tttccatcag gcttcttttc tatccatgta
    36961 cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg ttcttgacgc
    37021 gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt tcacgccact
    37081 tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt ttgagggtct
    37141 tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct ggaactagca
    37201 cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa gccaagatat
    37261 ttttattagt ttggctagtg acaatcttgt gctgttcttc gttgatttcc ttgatatcca
    37321 aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa cgtggtttat
    37381 tacggaaagg aagagcacag gtatccaagg tacagtggat tccttgttcc ttagccttgg
    37441 tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg actgtaatcc
    37501 cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca tcatctaccg
    37561 tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg caatactggc
    37621 aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca tctactgacc
    37681 caaagctttc tgtcgaatgc accattcctg tcacttgtcc ataatcaatt gtttcttcag
    37741 acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga cttgaaggaa
    37801 aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca ttttcaatct
    37861 attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt cctcagggcg
    37921 ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt ccgcagaacg
    37981 taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat catgaattac
    38041 cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt tatcattgtt
    38101 ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat gggtcacgtt
    38161 gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg ctgaggcatc
    38221 cacacctaga taggtacggt aggtttcctt cttatgagtc actcttgtga ctagagcacc
    38281 gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac caagacctgc
    38341 tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg cgatatcgtt
    38401 cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga taaagtctag
    38461 cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac gagccaactc
    38521 tggataatag agatgggtca cggtattgga cgctaggaag gagtgaatcc caaaagtctt
    38581 ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg tcatgccaaa
    38641 cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc ctccaggatt
    38701 ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt caatatcttc
    38761 aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt ccttgtctgg
    38821 cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat ggctcatcaa
    38881 aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa ttttcaaaat
    38941 agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt tccacgaaaa
    39001 agcttggttg acggctcttg ccttctcacg aatccccttc tcatcataca agtgaaaggg
    39061 agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg gtgttttcat
    39121 aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa cctttagttc
    39181 tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg cttggttctt
    39241 gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt cacgttcttc
    39301 ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact cgcgcaagag
    39361 actaatcata ccattgaccg ttccgccacc tttcaagaag tcatccacaa tcaagacacg
    39421 gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt caccacttga
    39481 acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt cacggcgcac
    39541 aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca cacccttagt
    39601 tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa taatacgacc
    39661 aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat aaccacctgg
    39721 caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt ccttagcatc
    39781 ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca ctgtctggat
    39841 atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt ctgagatgga
    39901 tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt tataaggatt
    39961 attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt tcatttctat
    40021 ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg tcgctggtgg
    40081 ttcaaaacac tgttttgaga ttgtcaatag aactgacaaa ccctgtaata tacctgcata
    40141 tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga gtattcattt
    40201 ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta tcctaaaaaa
    40261 tgctcatttt tcttaaatta tcaatctaaa tctggtttat agaaggaacg attatccata
    40321 gcgaagattt tattggtcat ctctccttta tccaccaaag ccagagctgt tgacatcatc
    40381 atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat aatacgtgga
    40441 cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg acgaagcaaa
    40501 acgacttctt ccttggtatc atcgatgccg agttccataa ctgtcttggt aatttcgcta
    40561 tcaatgagag cgatatgtcc aagaagatta cctcgcactg tgtactctgt ctggtctggc
    40621 cccgtcaact cgataacctt agctaagtca tgcagcataa tccccgcata gagcaggctc
    40681 ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgtaccat ggtcgccgta
    40741 tgataagcca accccgtttc aaaggcatgg tggttggtct tggcagctgg ataggagtag
    40801 aattccttat catacttggt gtagagattt cggacaatcc gttgccagac aggattttca
    40861 attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac tggtgacttg
    40921 accttgaaat cggctgggtc attgggttca ccagcttgag gcaggcggag agtaatttga
    40981 ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac aaccttacct
    41041 gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc aatctcgcca
    41101 ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg cctcaggtca
    41161 gctgatttga ttaggtaaaa gccttcaaat agctcatctt ttttcatgtg actaatcttc
    41221 atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac cttctgacaa
    41281 ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata attcatcaat
    41341 attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac caaacttgcc
    41401 aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct tttggatatt
    41461 aagggtcttg aaaccaactg atagagagtt aagaagggct gatagggtac ttggtcctgc
    41521 aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc gcacaatctc
    41581 tgaataaaga ccttctgtcg gaacaaacaa gattccaaag ttggttgtcc gaggtggtgc
    41641 tatgtacttg ttcctaatat ccctagcaaa gcgcttgacg cttgctagga gtgacttacg
    41701 acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc ggtaataatc
    41761 tgccagtgga aacttagagt caattggcag atagacgtat tcttggtcgc cttgtccggg
    41821 taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt attctcgttc
    41881 gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt ctcccagaat
    41941 ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac gggcaactgt
    42001 ctgcatttct ccaaggccac gattgacaga ctccagttgt ttagaaactg tctcaaagga
    42061 agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct ggcgcatttg
    42121 ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg tcttgtctct
    42181 agtttggagg agattatctg tcatttcttg acggacttgg gtcagacctt ggtgcaattc
    42241 aatccgcact tcttgcaaac ggtcgctgac aaccacttcc aaatcttttt ggtctaactg
    42301 gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat gatctgcctg
    42361 atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc aaatcagaaa
    42421 gagaccagct agattggcaa ttaataatag aataagtaaa ctttccatcc tacctcctgt
    42481 ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact tccctatcta
    42541 tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc aactcatact
    42601 tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga tagtcgtagt
    42661 ctgaacgagg ttctagctga ctgattcctt ctggacaata agtaatcaag ttttgcccat
    42721 cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc agaaagacat
    42781 tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc tgagcctgag
    42841 gattttgctt aaagatggtc aagagagcca attccaaatc agtatcatct ttttctggcc
    42901 gggcttggac aaaatactgg gcacgttttt gaatcacctg tcgctcttct tccgtcacag
    42961 aatcaaaatc tccgactgct agagcaagag gcaaatcttc ttccaagatc cagagcgagc
    43021 ctcgatccac accaacaaaa ccatcaaagt ccgtccgata atgaccgcgg tctccgcctg
    43081 caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc attgacatct
    43141 cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt ggattgagca
    43201 atagtttggt catcaatccc accatccact tcaatctcaa agttcaaacc tttttcatca
    43261 cgaagggcaa ccagctcacg aaccttatcc atggtttctg gcagaaaggc ttgaccacca
    43321 aatccagggt taactgtcat gactaggact tggtcaacta gatgaagcac atgcttaatc
    43381 gcttcaactg gtgtaccagg attgataaca actgatggct tgacaccgag tgaacgaatc
    43441 ttttggaggg caccatgaat atgaggcgtt gcttccacat ggatactaat aatatccgca
    43501 cctgcacgca caaagtcctc taaatgatgc tcagggtttg acaccatcaa gtggcagtcg
    43561 aaaaccatct tactatgagg acgaagagct tcgaccacac ccgcaccaaa actgatttgc
    43621 ggcacaaaat gaccatccat aatatcgata tgggcatact ctgccccagt tgcttctagg
    43681 cgtttaattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg agcaatcttg
    43741 tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt tataggtttc
    43801 tctgcgattt tcaatttcgc tgaggaattg caggtagttg tcaaaacgga agggtgcaat
    43861 ggtaccttct tcaactgctg gcttgacagc acaggacggc tcatgggtat gggtacaagt
    43921 acggaatttg cagtctcgac tgacagtggc aatctctgga aaggcctgat tgaggtcttc
    43981 agccgttgat acttcataat ccagtgatga aaagcctggt gtgtctgcga ttttaccccc
    44041 attgaggttg taaaaactaa cagctcgagt ggtatgacgc ccgcgaccca gactgtctga
    44101 aatttctccc gtttcaagat taagatctgg tgcgatttta ttgagaagag ttgatttccc
    44161 aacacccgtc tgccccataa agaccgtaac cttgcctgtt aacaaaggca ggagttcctc
    44221 tttactggtc acaaagtcat atccgatgtc accataggtc tgctggtaaa aatccagttc
    44281 tcccccgtct tccaacaaat ccattttaga aatatagacg atgggatgaa tacccttatg
    44341 ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt ccttgacaga
    44401 catgattact acagcttggt cgatattgac aataggcgga cggaccagac tgtttttccg
    44461 ttcgtgaatc ttgagaatat agccttctga attttcctcg gcagagaaat ctacccagtc
    44521 cccaacgtaa ggggtatgcc cttttttacg gaaattccca cgcgcgcgtg tttgatagac
    44581 ttggccatca ctctctacat agtagaaccc agccaaggct ttaatgattt gtccctgcaa
    44641 aataactcct ttaaaattgt tagttccatt ataacaaaaa aaagctattt tagcttagct
    44701 tctctttaca atttcgataa gtctattcta aaagaaaaag atacactcac gctttagata
    44761 ccaagtttta tacaaaaata acgaatctac ctccttatat aaaaacaggc gaacagagag
    44821 cctaaaactc cctgttcgct ttactttttc tgtgtgtaat agaaaaaacc taataaagca
    44881 agacaaaaaa tatgaatata aactccatac atcatgtggg gaaagacaga ctctataaaa
    44941 tagcctggta gatagatgat tggaaattga tagaaatcat aggtcgttag agatagtaaa
    45001 caaagaacat acataaatac tgctacaatt agaacccatc cttgctttcg ccatagaaaa
    45061 atcatcaata agaacagaca aagtagatag attgaccaat ttcgcaacat aaattgaaaa
    45121 ccataaatca tactttcagt cgtttctcca tcaatcacat caactacttt atagaaaggt
    45181 aaacaatagc tcactaaaaa aagaagggga ctaattattt ttttcatatt ctctaccatg
    45241 gattattttg caagtaagct gaccatctat ctccatatcg aatcaaatta acagtataat
    45301 tagttactac ccgattttca cctggtccaa ccttagaaaa acctgtgcta tactcccaac
    45361 tacttcttgc acctggatga aaccattttt gctgggatga ataccaacca ccttgtctaa
    45421 cttccacact tgaagattct atttcgatat ccctttcatg gaagtcaact cctccactta
    45481 ttttagtaat atttttttgt acacctccat cataactcac ccagtgaaca acagtataca
    45541 attccacact ataagtacta tcaaactgac tttgatgagt agtaatgttt tgagtataag
    45601 cgtgcacttt ctgtatacca aaaatatggt ctaatatatt cgttggttta gcaagcttat
    45661 tgtaaccctc ttcaacaaaa gtagccttct ctaaatcagc ggtataaaca gtttttcctt
    45721 gtactacttg attgtttata gaagtaatac ggctatccac aacaatgggg gccaccatat
    45781 ctccatcgct agtttctatt ttagctgcct ctttcacctc atatacaact cgattttctt
    45841 cagactgaat cacttctacc ccattttttt caggtataga taatctagtt tgcccattag
    45901 aaaccgttat atttggacca atattcttct catttgcata agtcgcaata ggaaatcctg
    45961 atagaaccac tgcacacata aggctattga ctaatttttt tctcatgaat atatccttcc
    46021 cattttcaag aggagtaaaa atagctaata taagatgaac gtttccttat atttcagaat
    46081 aggatatcta tctgaaagca attcacactc ctataggtaa ctgttccaaa tcttggctac
    46141 atatatttca atagtttgct acaaaaaact cctttctaag tctattgaac atgcccttat
    46201 tcacctacta atatatcaca aaaataaata aatacaagac tgttttttct actagtttta
    46261 tgatagaata gtattgttag ggtaaatttc atatataaat gtcgagtgaa aaatcgatgg
    46321 agcagaaatc ggtagacaaa gactcgattt cgttggtcca gccccacaag gctaatcagg
    46381 tatttcacga gtttaaaaat ctaatgaagt gcccaatcaa ctactgattc attgatttaa
    46441 tacgaactat agtggattga acctagaaat agtacactaa ggattctaaa acgtttctag
    46501 aaattaattt gactttccta atctctttgt tcatatctta tttcaatcta ctatatatac
    46561 caaaatgctg ggacaaaagt ctttaaaatc agagaaacgc atattatcag gtgttggaaa
    46621 accttgataa tatgcgtttt atcatagaaa gatctacttc attttttacc aaaattaagt
    46681 ttttgtccct gcatcttaga gtccttgccc tttaagtgca tctgctaggc tggcaaactc
    46741 ttccaagctg agagcttccc cacgcacact tggtgacaag cctgcttggt ccaaagcctt
    46801 ggtcagcttg tccttgacct cttcagtctt gccaaagtaa cctgtcaagt tattccacaa
    46861 ggtcttgcgg cgatgggtaa aactagcctt ggaaacctta aagaaaaagt tctcgtcttc
    46921 cactgctaca gctggcactg gacggcgcac cattttcaag atggctgagt ctacatttgg
    46981 tgctggcaca aagactgtac gcggcacgat aaaggcaacc ttggctgtca tgtaatactg
    47041 cacagcgata gacaagctac cgtaagcctt ggtatttggt tgagccgaga tacggtccgc
    47101 cacttctttt tgcatcatga ccacaaactc actaaaagga atgccactct cgattaagtg
    47161 catgagaata ggcgttgtga tgtagtaagg caaattagcc actaccttga ttggcaggtc
    47221 aggatttttg aaattctgga tatgttgcgc caaatcgacc ttgagaatgt cctcgttgac
    47281 tacagtcaca ttgtcaaaat cacgcaaggt atctgccaaa atcggtacca aacgatggtc
    47341 gatctcaaag gccataactt ctgctgcacg ctcagccaaa aactcggtca aggcaccaat
    47401 acctggcccg atttcaatga cattgacctg gtcatcaatc tcagccgtat ccacgatttt
    47461 ttgtaggata ttggtatccg tcaagaaatt ttgcccaaag gactttttaa aggtaaaacc
    47521 gtgacgctcc agcactgcct tggtcacgct ataatctgca attctcatct attctctttt
    47581 ctattatctg ttactactat tgtaacacat tccccttgta ttttgggggt gaaaatcata
    47641 ccaaaaaact atctttcctc atgaagaaag atagtcttgg aaatctttaa aagtggcctt
    47701 agcgcttctc tcgaaacata cgtt
//
LOCUS       DAVBOU010000011        44525 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBOU010000011 DAVBOU010000000
VERSION     DAVBOU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44525
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.011"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..226
                     /locus_tag="VQ879_000643"
     CDS             <1..226
                     /locus_tag="VQ879_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3142851.1"
                     /translation="TPSVIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEK
                     TWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(261..1058)
                     /locus_tag="VQ879_000644"
                     /pseudo
     CDS             complement(261..1058)
                     /locus_tag="VQ879_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1323..1559
                     /locus_tag="VQ879_000645"
     CDS             1323..1559
                     /locus_tag="VQ879_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3142852.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1790..3076
                     /locus_tag="VQ879_000646"
     CDS             1790..3076
                     /locus_tag="VQ879_000646"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3142853.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3308..4456)
                     /locus_tag="VQ879_000647"
     CDS             complement(3308..4456)
                     /locus_tag="VQ879_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3142854.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4631..5443)
                     /locus_tag="VQ879_000648"
     CDS             complement(4631..5443)
                     /locus_tag="VQ879_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3142855.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5481..5861)
                     /locus_tag="VQ879_000649"
                     /pseudo
     CDS             complement(5481..5861)
                     /locus_tag="VQ879_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5874..6137)
                     /locus_tag="VQ879_000650"
     CDS             complement(5874..6137)
                     /locus_tag="VQ879_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3142856.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6137..6370)
                     /locus_tag="VQ879_000651"
     CDS             complement(6137..6370)
                     /locus_tag="VQ879_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142857.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6370..6738)
                     /locus_tag="VQ879_000652"
     CDS             complement(6370..6738)
                     /locus_tag="VQ879_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3142858.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7023..7169
                     /locus_tag="VQ879_000653"
     CDS             7023..7169
                     /locus_tag="VQ879_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142859.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7213..7587
                     /locus_tag="VQ879_000654"
     CDS             7213..7587
                     /locus_tag="VQ879_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142860.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7580..7783
                     /locus_tag="VQ879_000655"
     CDS             7580..7783
                     /locus_tag="VQ879_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3142861.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7800..7997
                     /locus_tag="VQ879_000656"
     CDS             7800..7997
                     /locus_tag="VQ879_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142862.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            8008..8169
                     /locus_tag="VQ879_000657"
     CDS             8008..8169
                     /locus_tag="VQ879_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142863.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8164..8589)
                     /locus_tag="VQ879_000658"
     CDS             complement(8164..8589)
                     /locus_tag="VQ879_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142864.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8643..9356
                     /locus_tag="VQ879_000659"
     CDS             8643..9356
                     /locus_tag="VQ879_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3142865.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9369..9626
                     /locus_tag="VQ879_000660"
     CDS             9369..9626
                     /locus_tag="VQ879_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3142866.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9712..10032
                     /locus_tag="VQ879_000661"
     CDS             9712..10032
                     /locus_tag="VQ879_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142867.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10048..10344
                     /locus_tag="VQ879_000662"
     CDS             10048..10344
                     /locus_tag="VQ879_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142868.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10337..11164
                     /locus_tag="VQ879_000663"
     CDS             10337..11164
                     /locus_tag="VQ879_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3142869.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11304..12074
                     /locus_tag="VQ879_000664"
     CDS             11304..12074
                     /locus_tag="VQ879_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3142870.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12089..12283
                     /locus_tag="VQ879_000665"
     CDS             12089..12283
                     /locus_tag="VQ879_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142871.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12283..12510
                     /locus_tag="VQ879_000666"
     CDS             12283..12510
                     /locus_tag="VQ879_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142872.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12637..12804
                     /locus_tag="VQ879_000667"
     CDS             12637..12804
                     /locus_tag="VQ879_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142873.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12791..13000
                     /locus_tag="VQ879_000668"
     CDS             12791..13000
                     /locus_tag="VQ879_000668"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142874.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEYDGRVKAKS"
     gene            12972..13301
                     /locus_tag="VQ879_000669"
     CDS             12972..13301
                     /locus_tag="VQ879_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142875.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13291..13716
                     /locus_tag="VQ879_000670"
     CDS             13291..13716
                     /locus_tag="VQ879_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3142876.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13716..14230
                     /locus_tag="VQ879_000671"
                     /pseudo
     CDS             13716..14230
                     /locus_tag="VQ879_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14227..14616
                     /locus_tag="VQ879_000672"
     CDS             14227..14616
                     /locus_tag="VQ879_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142877.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14616..14852
                     /locus_tag="VQ879_000673"
     CDS             14616..14852
                     /locus_tag="VQ879_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3142878.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            14849..15007
                     /locus_tag="VQ879_000674"
     CDS             14849..15007
                     /locus_tag="VQ879_000674"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142879.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15219..15620
                     /locus_tag="VQ879_000675"
     CDS             15219..15620
                     /locus_tag="VQ879_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3142880.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15809..16351
                     /locus_tag="VQ879_000676"
     CDS             15809..16351
                     /locus_tag="VQ879_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3142881.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16515..16706
                     /locus_tag="VQ879_000677"
     CDS             16515..16706
                     /locus_tag="VQ879_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142882.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16826..17146
                     /locus_tag="VQ879_000678"
     CDS             16826..17146
                     /locus_tag="VQ879_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3142883.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17284..17676
                     /locus_tag="VQ879_000679"
     CDS             17284..17676
                     /locus_tag="VQ879_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3142884.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17669..19399
                     /locus_tag="VQ879_000680"
     CDS             17669..19399
                     /locus_tag="VQ879_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3142885.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19407..19625
                     /locus_tag="VQ879_000681"
     CDS             19407..19625
                     /locus_tag="VQ879_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142886.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19643..20845
                     /locus_tag="VQ879_000682"
     CDS             19643..20845
                     /locus_tag="VQ879_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3142887.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20829..21404
                     /locus_tag="VQ879_000683"
     CDS             20829..21404
                     /locus_tag="VQ879_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3142888.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21401..22573
                     /locus_tag="VQ879_000684"
     CDS             21401..22573
                     /locus_tag="VQ879_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3142889.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTNGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22585..22875
                     /locus_tag="VQ879_000685"
     CDS             22585..22875
                     /locus_tag="VQ879_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142890.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22878..23159
                     /locus_tag="VQ879_000686"
     CDS             22878..23159
                     /locus_tag="VQ879_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3142891.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23146..23445
                     /locus_tag="VQ879_000687"
     CDS             23146..23445
                     /locus_tag="VQ879_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3142892.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23442..23789
                     /locus_tag="VQ879_000688"
     CDS             23442..23789
                     /locus_tag="VQ879_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3142893.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23786..24109
                     /locus_tag="VQ879_000689"
     CDS             23786..24109
                     /locus_tag="VQ879_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142894.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24121..24699
                     /locus_tag="VQ879_000690"
     CDS             24121..24699
                     /locus_tag="VQ879_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3142895.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24711..25130
                     /locus_tag="VQ879_000691"
     CDS             24711..25130
                     /locus_tag="VQ879_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142896.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25408..28167
                     /locus_tag="VQ879_000692"
     CDS             25408..28167
                     /locus_tag="VQ879_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3142897.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28164..28886
                     /locus_tag="VQ879_000693"
     CDS             28164..28886
                     /locus_tag="VQ879_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3142898.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28887..32108
                     /locus_tag="VQ879_000694"
     CDS             28887..32108
                     /locus_tag="VQ879_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3142899.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     ATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            32154..33713
                     /locus_tag="VQ879_000695"
     CDS             32154..33713
                     /locus_tag="VQ879_000695"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142900.1"
                     /translation="MDISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRASGI
                     RQEILNATKDKADKTLVTAEAGKLREELTSLSVGENLFVNSDFKNLRDNGQRYTANGK
                     TYQNMIAPYWYNPYNAGIPNAQNIQHGYFDTETFSDTVFAFNESDGSRHWKALSTDFK
                     IGVISAGEYYFSADLYATDLGTHIKFGFYYHNSTGKLNFYAGRTKIEVTEKGRWTRLG
                     IDLKVNDDIDLTKKVQFYIYGYNFASNSILYLKKPKVSKGRLKSDWSPALEDTEGLIT
                     EAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESTRQATAVRELVNRDFV
                     GKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGG
                     QISGLSNRLTSSEQGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGR
                     ISDQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVA
                     RMALTNQLFQV"
     gene            34104..35486
                     /locus_tag="VQ879_000696"
                     /pseudo
     CDS             34104..35486
                     /locus_tag="VQ879_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35467..35670
                     /locus_tag="VQ879_000697"
     CDS             35467..35670
                     /locus_tag="VQ879_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142901.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35673..36025
                     /locus_tag="VQ879_000698"
                     /pseudo
     CDS             35673..36025
                     /locus_tag="VQ879_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36035..36451
                     /locus_tag="VQ879_000699"
     CDS             36035..36451
                     /locus_tag="VQ879_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3142902.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36455..36790
                     /locus_tag="VQ879_000700"
     CDS             36455..36790
                     /locus_tag="VQ879_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3142903.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36790..37746
                     /locus_tag="VQ879_000701"
     CDS             36790..37746
                     /locus_tag="VQ879_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3142904.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(38016..38195)
                     /locus_tag="VQ879_000702"
     CDS             complement(38016..38195)
                     /locus_tag="VQ879_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142905.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38337..38486)
                     /locus_tag="VQ879_000703"
     CDS             complement(38337..38486)
                     /locus_tag="VQ879_000703"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142906.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38768..39235
                     /locus_tag="VQ879_000704"
     CDS             38768..39235
                     /locus_tag="VQ879_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3142907.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            39268..39365
                     /gene="ffs"
                     /locus_tag="VQ879_000705"
     ncRNA           39268..39365
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ879_000705"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39422..39865
                     /locus_tag="VQ879_000706"
     CDS             39422..39865
                     /locus_tag="VQ879_000706"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3142908.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39867..40382
                     /locus_tag="VQ879_000707"
     CDS             39867..40382
                     /locus_tag="VQ879_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3142909.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40396..41757
                     /gene="radA"
                     /locus_tag="VQ879_000708"
     CDS             40396..41757
                     /gene="radA"
                     /locus_tag="VQ879_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3142910.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41830..42327
                     /locus_tag="VQ879_000709"
     CDS             41830..42327
                     /locus_tag="VQ879_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3142911.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42352..42546
                     /locus_tag="VQ879_000710"
     CDS             42352..42546
                     /locus_tag="VQ879_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142912.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42528..43151
                     /locus_tag="VQ879_000711"
     CDS             42528..43151
                     /locus_tag="VQ879_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3142913.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            43296..44264
                     /locus_tag="VQ879_000712"
     CDS             43296..44264
                     /locus_tag="VQ879_000712"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3142914.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(44401..44525)
                     /locus_tag="VQ879_000713"
                     /pseudo
     CDS             complement(44401..44525)
                     /locus_tag="VQ879_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        13882 a         7648 c        10190 g        12805 t
ORIGIN      
        1 cacaccatcg gttattatta tggataatgc aagattccat agaatgggga agttagaact
       61 tttatgcgaa gagtttgggc ataaactttt acctcttcct ccctactcac ctgagtacaa
      121 tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat taccaagttg
      181 caataccttt tacgaggctt ttttatcctg ctcttgtttc aattgactat attagaggcg
      241 agacattttt cggttctttg tcaactgtag tgggttgaag aaagcgaaga tctagaaagg
      301 acaaatttcg tcctttcttt tttgaagttt tcaaagttcc taaaaccaaa ggcattgtgc
      361 ttgataagtt tgatgagatt attggtggct tccagtttgg cgttggaata aggtaattga
      421 agggcgttga cgattttctc tttatctttg aggaaggttt taaacagagt ctgaaaaaga
      481 ggtggaaaag caagagctga tagagattat agtggtgttt caagtcttcg gaatagctca
      541 aaagtttatc tagaatttct ttattagtca agtgcatacg aaaagtaggg cgataaaatc
      601 gtttatcact cagtttctga ctatcttgtt gaatgagctt tcagtatcgc ttgatagcct
      661 tgtattcatg ggatttcgga tgatggcttg tgttctgctc tcaagaacag ttatgatatt
      721 gagcttatca aagtcttgag caataaagct catttccatc tcccgattga aacagtcact
      781 ccccggactg tttcaacgtc ctaggacata atctcaggaa gacgcgaaaa atcatgctca
      841 aagtgaaaat cattgttctt gcgaatgaca gttgaagttg aaatagacaa ctgatgatca
      901 atgtcggtca tagaagtctt tttaattagc ttctgagcaa tcttttggtt gatgatacaa
      961 ggaatttgat gattcttctt gacgatagaa gtttcagcga ccatcatttt tgaacagtga
     1021 tagcacttaa aacggccttt tctaagaaga attctagttt gaatttttta tactagaaaa
     1081 tcagaaccat aatacctata taaaaatatt atagttctaa taggatttac ccaaaagttt
     1141 taaggcggtc tttttagaac tttaatcgtt tgaaatttag gtagcaaatt tgtttctatt
     1201 ttgtcaactt ttcctatttt tatcttgttg aggctggtat tttaacaatt caggaattga
     1261 tagtgaatgt gtaaaatttt ttgttagaat aagtttataa aaaagaaaag gagtatttga
     1321 ttatgttaca aaaaatttat gagcagatgg ctaatttcta tgatagtatt gaagaagagt
     1381 atggtcctac atttggtgat aattttgact gggaacatgt tcattttaaa tttttaattt
     1441 attatttagt gagatatggc attggttgtc gtagggattt tatcgtttac cattatcgtg
     1501 ttgcttatcg tttgtatctt gaaaaattgg taatgaatcg gggttttatt tcttgttgag
     1561 gtaattttag taaatttccg aactaattta ctcttttatg gaaagataat agtaaatagc
     1621 tagtaatttt tctaaatcat tttttaatag ttggaaatag caaatctttc tattgtttct
     1681 tcttgataaa aaggcgattt tttattataa taaattgtaa gatataattg caggtgagag
     1741 tcctgccatg tatgtgagaa aggaagagcc tgagggctca gacaaaatta tgacttcagt
     1801 tgttgttgta ggtacccaat ggggtgatga aggtaaaggg aagattacag acttcctttc
     1861 agcgaatgca gaagtgattg cacgttacca aggtggtgat aatgctggtc acacgattgt
     1921 gattgacggt aagaaattta agttgcactt gattccatct gggattttct tccctgaaaa
     1981 aatatctgtc attgggaatg gtatggttgt aaatcctaaa tctcttgtaa aagagttgag
     2041 ctatcttcat gaggaaggtg taacaactga taacttacgt atttctgatc gtgcgcatgt
     2101 tattttgcct tatcatatcg agttggatcg cttgcaagaa gaagctaagg gcgacaataa
     2161 gattggtacg acaattaagg gaattggtcc agcttatatg gacaaggctg ctcgtgttgg
     2221 aattcgtatt gcagatcttt tagataaaga tattttccgt gagcgtttag aacgtaacct
     2281 tgctgaaaag aatcgtcttt ttgaaaaatt gtatgacagt aaagcgattg ttttcgatga
     2341 tatttttgaa gaatattacg aatatggtca acaaatcaag aaatacgtga tagatacatc
     2401 tgttatcttg aatgatgcgc ttgataatgg caaacgtgtg ctttttgaag gtgcacaagg
     2461 tgttatgcta gatatcgacc aaggtactta tccatttgtt acgtcatcaa accctgtagc
     2521 tggtggtgtg acaattggtt ctggtgtcgg tccaagcaag attgacaagg ttgtaggtgt
     2581 atgtaaagct tatacgagtc gtgtaggaga tggtcctttc ccaactgagt tgtttgatga
     2641 agtgggagaa cgtatccgtg aagtgggtca tgaatatggt acaacaactg gtcgtccacg
     2701 tcgtgtaggt tggtttgact cagttgtgat gcgtcatagc cgtcgtgttt ctggtattac
     2761 taacctttct ttgaactcta ttgatgtttt gagcggtttg gatactgtga aaatctgtgt
     2821 ggcctatgat cttgacggtc aacgtattga ctactatcca gctagtcttg agcaattgaa
     2881 acgttgcaag cctatctatg aagagttgcc aggttggtca gaagatatta ccggagttcg
     2941 caatttggaa gatcttcctg agaatgcgcg taactatgtt cgtcgtgtga gtgaattggt
     3001 tggcgttcgt atttctactt tctcagtagg tcctggtcgt gaacaaacaa atattttaga
     3061 aagtgtttgg tcctaagaga tttttaagat ttgtttaaga taggtcgggt atactataga
     3121 cagttataag aagacctcct aacttgttgt aacaaatatc ctaaactttt ctttttcata
     3181 ataatctccc ttaactccac ccaatcaggt ggagtttttt agctctattt caggcttttg
     3241 gggactattc taaaaataat ttttcgatat ttttcggatt ttggtcgggg aattggcggg
     3301 gactttttta gcgaatatga ctaagaaata ggtctgttgt cgcttcagca agttcgtcct
     3361 ctacttgatt gtaacgatcc gtcatataaa cctttgtatg ccccagcgcc tggcttaatt
     3421 gttcaagcgg aacccctgca ataatgcttt gagtcgtgaa gaagtggcgc atcatgtgag
     3481 gtgttacatg caatcctgtt gcttcattca ctagattgaa gtttctattt agctgatttg
     3541 gattgatgag accacctttc tcgttgatag ttatataatc cttgtgctgt tccttgataa
     3601 ttcctaactt tcgcttaatc ttagaagctt cagctatcag ataatagatc aggtctgttc
     3661 cgatatcatc aaggcagaca tatcgctctg aatccttcgt tttaagccct cctttccctt
     3721 ttaaggtctg gttgcttcga ctgtctctaa gatgcagtat agcccgtccg ctgtcgttct
     3781 gagtgatgtc cattggacgc aatccaaaga cttctcctct tctcaatcca aaaattgtca
     3841 gataggtcag agcgtagaat tgttttggca taatctcttc tgcctttgct atccaagtct
     3901 tgaactcttt gagagtcact ttcttgtttg cagcagggat atcactctgg ccgatgaaaa
     3961 cacctttcaa gcgatttgag agcagatttc catttttgac ggcatcattc agcaatgcca
     4021 tgaagctgga attgagggtt tgaacagtgt atctggtatg gttctgcaac ttttcagcga
     4081 taaatagttc atactcattt ctatccaaat ttttaagcag gatagaacca aactttgcct
     4141 tgatatggtt cttatagaga ttgtcattga ggtagtagga agtgtcattc cagcgccctg
     4201 ttgacaatct cttttcagaa tagatatccc aatattgatc aagcgttaga ttcgtattga
     4261 tacctaattc ttgttcttgg atttgttgct caagctctac caaggctgca cgagcttgag
     4321 ggagagttgt gaaaccactt ttactttttt ctcttttttt acctcggaag aaaaaagaac
     4381 gtctgacata gtaacgcttg cctttagcag tctcatagta atagatattt gggtattttg
     4441 ttttattata tttcattgta ttctccttgt ttatcggctt ctggacaagg tctaaacatt
     4501 gagaatattg acatcacccc tttcatggtg taaaataggg tatagaaaag aggccttttt
     4561 aatggctgat tttttataag ggtaagcttc acaatcaaac tttggcgagg gcgattgtgg
     4621 ggcttttttt ttattttctg aatagtttgt atagtttata caaactccaa gctgtcaaag
     4681 ggactgcaag gaatggagcg attggaatac caacaactcc aaaaaagact aagaaaagat
     4741 acagtgctga aaatatgatt ttattggcag gaagtttttt cttaggagat gtttctgaaa
     4801 gattaatctc gtttactata tcagcgacac tgtcactaac aatattttgt tcaatatgtt
     4861 cagtttcagt tgttttagtt tcaatagctt cagtttccgt aacttcttta ttggaaatgt
     4921 tatcatcaat tatctcagat gattcgctct gaattacttc tttttgtgaa gaatcaacaa
     4981 tggtaaggta aatttcaaaa ccaacatcca aatcattatt tgtgacaact ttttcttcat
     5041 actcgtccca ttctttatat gggccacctt ttatctctcc ctctattaca aagttatatt
     5101 ttttattatc aaaatatttt cgtattgttt tagcaatggt tgcaggaaca tatcctacat
     5161 gattatcaaa tatcaaaact tttatagcat taggatcata tctattatct acttctggaa
     5221 cgagctcaat attgaaaaag tctaaatctt gatatttgaa aactttcaga ccatattctt
     5281 caagttcttc tctaagttcc ttagttgata aattgctata gtactttgca tattctggga
     5341 ttccgttatc ttcagcaatc atattgcaag cttcttttac tgctttttta tattttgtca
     5401 ctccagcgac tctgaataat attttttcaa cagtcttttg catatatttc ccctctatat
     5461 aaatatcttc aatgcaattt ttaatttact aatgccaagt actcttcctt gaccatgact
     5521 tcattagtca tagtttttag attgtagtaa gacatgaatt tgaggtaatc aaactctgtg
     5581 gggtcgtcta agctttctag tgcgtctttc acgagatgat ggatcatatt cctatcagct
     5641 tcgttttcac agcgtaggcg agcgttttgg tactctgagc gtgtatggtc tttgtgtccg
     5701 agttagtgta gggcgacttg gatttgttgt tcaggagcta agttgtggtc aatagcgagt
     5761 acgtttgtgt ctggattgta gaaaccgcta ctgtgccagt ttgaaccgtc gaagagacaa
     5821 agctctactt gatattcttc gcagagttta gcgagtatca tagttctcct tcgttattta
     5881 taaacatctc tgcggtgggc gatttccacg gctaggacga ctagtttatc gtcttggata
     5941 tcacagatga tgcggtaatt ctctactctg tatcgccagt aacctgcaag gttggctttt
     6001 agtgcttttc cgtgttgtcg tggattggtc gtgttttcaa tgtttttagc aagccaggat
     6061 aggatttgtt ttctggttgg ggtatctagt tttttaagtt gcttgagagc ttttttatca
     6121 atatctagcc gatacattaa gcaatatcct ctcgagatag tcctagttca tccaagacct
     6181 catccatggt ataagtagct gggtcggcta aatactccat ataggcttgg tcggctgctc
     6241 gtgcgtcttc gatatcttcc atgagtacca tgaagtcgtc aaaatccatg gttgttgtgt
     6301 cgataccgtg tttggttagg tagtccgtga tgtaggagtt tttttctgtg aaattgatcg
     6361 tgatagtcat tagcgttctc ctttgctttt gaagtgggcg gatagaacgg atgtgatgaa
     6421 gtcgatatca tcttcattta gtggttttcc gtcaaataac atggtgttgg ctgctgcttt
     6481 gcgtaagtct atgatttgtc catttacttg agcaaattca tcacttccag cgatagcagg
     6541 attatctgtc cgtccgagta ggtagtcagc acttacatta aaataatcag ctatttcttt
     6601 taaaactttt gaactaggat tacttctttt taatcgatat aaagtattag ttccataacc
     6661 aagtttttct tctaaaatat ttatagaaat cccctgttta tcagctaatt cttttatttt
     6721 atcgaatgct acaaacatta atttttcaac ctttctaagc aaacgaaaaa taattttaaa
     6781 atatttgtag aaaatagttg acttatttag tcaaatgttt taaaataata ttcgtaagct
     6841 aaagagttag cgaactagac aactaaaaaa taaagcctta caaaactgat tggcgtccgt
     6901 ttactgtagg taaaacttac ttttagtagg tcttttctct atgtttttat tttaaaacat
     6961 ttgactagag ttgtcaagaa gttcgctaac tttttagata attttttaaa aggaggtcag
     7021 ggatgaacga agaagacctg aaagaattat tggaactctt agcgacagat tatgggcgag
     7081 ggtatctaga tggagtagtt gggggacttt caatgctttt gaaaatttca aaagaagcag
     7141 agaaatatag aaaggaaaaa tatgagtaaa gcaaaattat tagtcacata aagtaggtaa
     7201 acgaggtagg aaatgataga aacactggaa ataaaaataa acaaaaagac atacttcata
     7261 tctgcaaggg cagatgttcc agtcaggtat aaagttatgt ttggcagaaa tctcttcgat
     7321 gacttttcga aaataaaaaa caataaagat gaaactctat cactttgtct attattttgt
     7381 atgacagaca aatcgtcaga agaattctgt aaatttttta ttgaaaataa ttcatatata
     7441 acaagtagac atcactatga ggcaataaga ttatttgaaa aacattttat ctttaagccc
     7501 gtaacatatt cactagagga catagttcaa atcctaacaa tatatctaga aaatactaaa
     7561 acacagattg gaggaaaaaa tgagtaaaga actaaaaata attaaggcta aaattaaaac
     7621 tcgtttgatt gagttggata tgactcaagt cgaattggca aaacaagtat ctgtagcatc
     7681 atcagttatt tcagagttgc tgaagtatgg aaaaggaagt gattatgtga aagaaaaagt
     7741 cgtagatatt ttgggtattg aaaacccttg ggaaaatagt tagagcatga ggaaatagta
     7801 tgaacaacgc agcgcaaaaa gtaacacgga ttgacaaaga tgcctgggag attgctacgg
     7861 agctggcgaa cgagtacggc gtatctattt gtcacatcat cagcgagagc gtccgctact
     7921 gtgcagagaa tgccgaattt aaggagatgg acgttgtcgt taaacgattg gtagtcggca
     7981 gtaaggtgct ggagtaggag ggtggagatg aatgaactag tatggtttta ctttgttgtc
     8041 ataatcaatc ttatcattgg ttttgctaca tactacgcta gcaaaagaga tagagaaaag
     8101 cgcatcaacg ggtttaaaaa aatacaagat gatgagcttg aaagagttag aaataaattt
     8161 aatttatgat tttttagaag tcttttgaat aaatctttta tttaagtttt gtttgctatt
     8221 gcttgcttta ttagctattt ttaaagcttt gtcaaaatca acctcgcctg taaaaacttt
     8281 gtaggtaaga tcattcatct tcatagactt gtcggtttca gtatcaagct gagatacctt
     8341 ctcaagttct tgcaaccgta attcatgagc ttgtttgatt ttttcaagtt caaaggcatg
     8401 ttgctgtttt agagtatcta tctgatgatg aaattctctt tcgagttttt caacagtatg
     8461 tgaatgttct ttggcttgtt tttcaatctc agctttattg ttagcttttg atgcgacata
     8521 tgaccataac cctgatatta ttgcaagaat aatactaatc acaggttgaa taagagcttg
     8581 atattccata agatttctcc aatcgtttta ttttaattat accaaattta gaaaggaact
     8641 ttatgaacga aatttttaat tttcacgggc aggaagtccg tactttgatc attgatgacg
     8701 aaccttggtt cgttgggaaa gatgttgcag acatcctagg atatagcaag gctagaaatg
     8761 cgattgctct tcatgttgat gaagatgacg ccctaaaaca gggcctcaca gataatttag
     8821 gaagggttca agaaactatc atcatcaacg aatctggcct ctactctctt atcttatcca
     8881 gcaagttgcc tcaggctaaa gagtttaagc gctgggtgac atcagaggtt ttgccagcta
     8941 ttcgcaagca gggcggtttc attcgcgagg acttggacga ggatgccttt atcgctctgt
     9001 ttactggcca gaagaaatta cgtgagcaac aggcgaccat gctggaagat attgactatc
     9061 tcaagagtga gcaaccgatt cacccaagct atgctaaatc gctcctgaag aagcgtaagg
     9121 ctcgggtcgt ggtttgctta ggtggcattg atagtccggc ttatgcggat aagactttcg
     9181 ctcagtcagt ctttagacaa gctgagattg actttaaaga ccacttcaac attaatcgct
     9241 atgacttgct accgaaaaaa ttcgcagatg cagccttggc ctattggatg acttgggagc
     9301 caagcaccaa taccaagatg aaaatcatga aattgaactc atttgacgaa gggtaggagg
     9361 ggaagaagat ggacaatgtt ctactttcac tgtctgaatg gattaaatcc attatcaagg
     9421 acacaatcac aaggctagtc gaaatagaaa aagatagtga ccactatcca gagctgatgg
     9481 atgtgaacac tacctgtgat tttctaggaa ttaagtatgc caccttttca gataattatc
     9541 gttacttaaa gggatttcca aaggaattac ctggtaagaa atggtcaaaa agagccatca
     9601 aagaatggct ctctaatcaa atataataac tttactaaaa ggcttctgga caaggtctta
     9661 gcaaaattat ttgactatat tatagcacaa aaagaggata aggagataaa aatgtttgaa
     9721 ccaccgattt tagaccagct gatgggggtt ggagccttac tgcttggatt tgcaggggct
     9781 tgccgtcata tcaaattgca ggaacaacgc aaggaagaag aaagacgaga agagcaagaa
     9841 tttgcgtcta tgattatcca agtgcgtaat catgcatatg aacgtggtag agaggacaaa
     9901 tggcaagaaa ttcgcaagaa tattcgcaga gagttcaaag gattcacata tgacaacgaa
     9961 ccgcctgtag gcttgcgtcc tgagccgtta gctttgccag aacctaaaca gtctgcaatc
    10021 agatttttgt aatgaggagg tcaggaaatg caagaattga ttgaatcgct ggataacctg
    10081 attatgattg ttaaagaact ggaaggaagg gaatcaactt caagacattt tattacgata
    10141 tgggaaaacg attataaaaa tctattacga gtcaaagaat acctaaccga ctatgaaaaa
    10201 ctagcaaagg actatcgtta tatgaccctt aaaaataagc tgctaaagat tgaaaaaatg
    10261 gagctggaag gcaggtacat ctatgaagat atgcggatga agtatcgtgc caatcgcagg
    10321 aagtggggtg ctcggtatgt ctgaaatcaa gtggataaaa atcaaaacgg atatttttga
    10381 cgatgaaaag atgtgtctaa ttgatgcctc gcctgatcgt gatgcaatta ttgtaatctg
    10441 gatcaaactt ataacactag caggcaaatt gaatacaaaa ggcgtactaa ccatttctaa
    10501 aaacattgta tacaccgatg aaatgcttgc acaaacgttc caccgtccgt tgaatacagt
    10561 tcgtatggct cttgaagttt ttgaaaagtt tggaatggtt gaaaaaatcg atggagtgat
    10621 aatgttaccc aattgggaga aacatcagaa cattgacggc atggaaaaaa taaaagagca
    10681 aaatcgaaat agagcagcac gtcaccgaca aaaacagaaa ttacttgcac agaacaacga
    10741 aagtaacgtt actgataacg ttatggataa cgttacagta acgcatggta acgcactaga
    10801 taaagaatta gataaagata tagagataaa taataataag gtgatgatta gttccagcct
    10861 ttctgaaaat ttgaaaaata gcggaatcca tctaactgat aagtcacatc aacagttact
    10921 tgattatgtg ggacttgatg gaatgagttt cgatatgttg aaccgtgcag tcgagaaaac
    10981 ttccggatca cacaaaccta gtttcaatta cctaatagcc attcttgaaa gttggaaaaa
    11041 gaaaggcttc acatcgattg agcaggtgga tgaggacgac cgtaaatata aagagggtaa
    11101 gaagtcaaga caacaaaacg ataaaacatc ggaacaggag gtaagggacg aatggggatt
    11161 ttagaactaa ttgagcagtt cgagattgac tattatccgt taagctacga gaagaaaact
    11221 cttttagcag accaaccaat tcatccagtg gttgcctgct tgtctgaaat ggctagctgg
    11281 catgaatgcg gaggtcggct agtatggtag acaatgtgtt tgaggaaatc gccttatctt
    11341 atcgtaggaa tacagaacaa caagaagagt tctgcgaaaa gcataacatc cctttgataa
    11401 agatattgag gaccgagagt gttgtatgtc gcatgtgtga atctgagcgg attcatgaag
    11461 aaaatcagga aagagtgaat gaactggcta atgctgagaa tgagcgagag aggaaatact
    11521 atcttgaaaa gttctctctt tatgatgaaa ttttgaaaaa tgctactttg gacaattttg
    11581 aaacaccaac cgaaaaagaa gcggaaaagc tagcttttgc aaagaggatt tgtcgtgagt
    11641 ggtctgaggg tgctaggaac aacattgtac ttcagggaga agctggaact ggtaagagtc
    11701 atttggcttt tgctatggtt aaggctctat ctgagtacac gaaagagatt gctattttta
    11761 ttaacgtaac tgacttgctg atgaagatta aagctgattt tagtcaggaa gagtttctgg
    11821 tcaataaaat tgctagtgct aagttcttgg ttttggatga tttaggaatg gaaaaagata
    11881 gcgaatggtc atttactatt ctctacaata tcttgaataa gcgttcaaac acaatcatta
    11941 ccacaaattt gatttctgcc gatattcaaa aaagatatgg cagacctttc atgtccagac
    12001 taatgaaggg tgtagataaa gaccatttga tggttttcaa tgatttgaca aacaagcgaa
    12061 agcaatattt ttagaatagg ggtggctgat gtttatttta aagcatggga caagagagga
    12121 taagccgttt ctaaggtctg caattatcag tgtgactggc ttggatattt cgtgttctga
    12181 ggagaagaaa gccatgcggt ttatttctcg ggcggcagcc ttacaggtta gcaaggcatt
    12241 gagaggttcc tttgggaact tctaccctgt cgaggtggag tgatgttaga gctttatttc
    12301 gtctacaacg ggcactgtaa gtttttcctt gggaggtttg acaatgtcga tgatctcatt
    12361 gagcagatgg aagaccatca gtgggctttc tcagctatca ctcatccaag gtttcagaag
    12421 cacattggtc agcggacgac acgatttgac tacggttcta aggattgtta ctatttagcg
    12481 actttttcag gaggagaaaa aaatgattga acttattaaa gaatttggaa tggctattct
    12541 gtggttattt cttggctatt tagtcgggga acgtgcagca agaaaggaaa agaaagatga
    12601 tcaataacgt tacattttta gtgggaggta agaaacatgg ttggagtaac ctatcaggaa
    12661 attcatctct ttgttgaatt tttgaaagag cagtacgggc aaggtcgtcc agactatatt
    12721 gaagccctga acgacttaga cggtctggtg gaagtctcct acagagaagc tattgaaaga
    12781 tttttagaag atgaagtacg ataaacaggc tgagattgac ggactgaaac gcacgatcga
    12841 gcaaaacgaa gagaagataa tcgagtattc gaagccgtgc gatgcacgca agagacggat
    12901 tagagcgctg gagcgcgatt tgttgaggaa aaagaataaa gaattaagac ggaaagcgga
    12961 ggagttggaa tatgatggaa gagttaaagc aaaaagttaa tgaagtatac aactggacgg
    13021 tagaagacgg gaagccgcaa cctcccaagc aagatttacc acaagcggtg aaagaccggg
    13081 cggactattt ttgggaaatg gcagaagatg gtatgacgtt tatgggagcg atggaatgca
    13141 tcttcgctga tgaaaagcct acagactatg atttgggagc tactaagggt tggttgccaa
    13201 aatctaagga gtttgatgat tgggttggct attcgccaag catgtctcag ttagttattg
    13261 cagtttattt gatttacaga ggaagcgaag atgaaactta atgaattgat taagaaatat
    13321 aaaaaacttg agggtgtatg gaatgctgaa ggagcagaac tagttcgtca aatttttctg
    13381 caagacttgg aacaactaga taaaccgcaa ccagtcaaag ttccgcagtg tgtggcggaa
    13441 tatatagaat ttaaaaagaa aaacaatttt catgtttacg gtcttgcttg gcttaacggc
    13501 tacgaggtcg aaaaagagaa gcggtatttt gttaagatta aagggaatat taaagaaaat
    13561 atgttggttt atggagaact tttgaaaagg tatttcttta caaaaagctt tagtttagac
    13621 gatgttatat attcccacac tcgtaaagaa ctagaagccg caaacttcgg ctgggtgttt
    13681 gattgcccag gtattgagat tgaggaggtg gaataatggg agatatacga atactagacg
    13741 cttgttgtgg cagtcgtatg ttttggtttg ataaaaatga gagtcataca actttcatgg
    13801 acatcagaca agaaaaattt gaaatacatg gaaaaaggta aacgtaaacc ctgacgttgt
    13861 cggagatttt cgtgatatgc cattcgatgg tgaaacattt aatctagtag tatttgatcc
    13921 gccacatttg aaatgggcag gtcaaaactc aattatgcga tcacaatatg gccagctgga
    13981 taaagttacc tggtcggaag atttagccaa gggttttgaa gaatgtatga gagttctaaa
    14041 agttggaggt actctagttt ttaaatggtc tgattgtcaa atcaacgtta aagaagttct
    14101 taaatctgta ccttttaaac cattgtttgg acaacaaaga ggtactacgc attggatgac
    14161 gtttatgaaa tttgagaagg tcacagagag aaaggacggc acgtttgtaa aagaggagga
    14221 tttggcatga taccgaaatt tagagtgtgg catcatgaat taggtagact gatgtcagtc
    14281 aaatgtatgt tttttcagga tagcgagatt gaagaatttg agttaaacga tgctttaatg
    14341 aatgattaca ttacagctta tcctgatgaa atcgaactca tgcaatcaac aggactcaaa
    14401 gacaagaacg gcaaggaggt attcatcggt gacatcgtta aatgtacaag aggatgtctc
    14461 catgaagtat atttagaaaa agaatacggt ggtacattca taggtggaat gcctgctgta
    14521 tacctaaaag gacttggaga tggatatgcg tggacggaat atgaggaaat catcggcaac
    14581 atctacgaaa atccagagct tttggaggat aaataatgaa cccagaaata attgacaata
    14641 taaacaaacc aagccactac caaggtgcaa acggtcttga ggctatcgat gttgtgcata
    14701 acttcgttgg gagcctttcc ggagcgtctg ctttcttttg gggcaacgca atcaagtata
    14761 tgttacggtt tcaaaagaaa aatggtctgg aagacctgaa gaaagctaga aagaatcttg
    14821 actggctgat tgaggagatg gagcatgagt gaatacgcat tgtatgaagg cgacaccttt
    14881 attaccatgg ggacgcttgc ggaaatcagc aaagaaacag gaattgctga acggtgcaag
    14941 tatttcagag tttgccatcg aagatatctg tacgtttttt gggattgaga tccaagaaag
    15001 gaaataaaag tcaatgaaca aaagaattaa gaagaagata gctaaacggc agatacaaga
    15061 aaagcaagaa gaattataca aacaactacg gaaattaagt tctgaagaaa ttgaagctat
    15121 aactaaaatg attaatcagg cagtttctaa tattcgcaag gctttctctc agatatttga
    15181 taacttgttt acatttttga aaaacttgga ggtggaaatt gaaaaaattg agcgacgaag
    15241 aactcaaaac gttagacaga gaacttttca aatttcaaaa cattcaacgc acaatagact
    15301 taagaaggct agaattagaa accagaaacc cagatgctca aagtgggcca actgtaggaa
    15361 taagcaaacc taccgaaact atcgcaatca gaatcgcaga tgatccgact ttaaaatttc
    15421 ttgaaggatt taaagggatt attaacaaac tcttaagcaa tctagtcgag gaggacaaag
    15481 aaattttcaa tctacgctgg agataccctc aactgagatg ggaagaaata gcagaacaga
    15541 aattcatgag caaagctaca atctatcgac gtagaaggat tatcttagaa cagtacgcta
    15601 taatgaaagg tgagttgtaa ataagattga gacaaaagac atcttgaagt ctcacaaaaa
    15661 aagggctatt atgatagcat gaacttctga aaacaaaaac acaaatcaca tgttggagtt
    15721 atcctatttt tacagaaaag ttgtttaaca gaggaacatc atgagtcagc aaccagctgg
    15781 ctttttgttt tgtagaaagg aggcagttat ggaatttgta tcaccgataa aagacaatga
    15841 taatattcaa gctatgaaag attatctcag agaatggaat gagatgtatt atatgctatt
    15901 catcacaggc ctgaatactg gcttacgagt cggagatata cttaccttga aagttaaaga
    15961 tgttcaaggt tggcacatca aactgagaga acggaagact ggcaagcaga taacaagacg
    16021 gatgacaaaa gaactcaaga aagaaatgag gagatatgtt gaaggcaaac catttcatca
    16081 tttcttattc aagagtaggc aaggtcagaa taaagcgatc actcgtgagc gagcctatca
    16141 aatcatacat gaagcagctg aagaacttgg cattgataat gttggcacac atacaatgcg
    16201 caagacattc ggctataaat attacaacaa gacaaaggac gtaggaacat tacagaaaat
    16261 gttcaatcac tcatcacctg caatcaccct gagatacata gggatagagc aagcagagct
    16321 tgatgacgca ctacggaact ttgtcattta attttttaga tattactttc acataatgag
    16381 ttaagcataa actgaaaaaa tgaaagtctt caaaacctat gattagtaag ggtttgagat
    16441 ttagagtgag tttaacaaaa tataagatat gtgaaagtga gggataaaat tggtatagtt
    16501 acaagaggtg aaaaatggta aaagaatacc gtgatgattt tcttggagaa aaggccttcg
    16561 agaaattaaa taaagatatt gatgccaatc ctgaagttgg ctttgaaatt gttggatata
    16621 ctcaaacagc atttgtaaat ggaatgcata taccgttaac agccatacta gtaaaatgga
    16681 ataatttttt taaagaatca gaatgagaca aaagacatct tgaagtctca caaaaaaagg
    16741 tttattatgg tagcatagat ttcttgtatg aggaggggat aggtcaaagg cctatccctt
    16801 ttagcattga gaaaggaggt ttgagatgta taacaaacct atcagaccat ccttgaaatc
    16861 taagaagtgg gagaagttcc gtgataggat aatgcgtaag catgattatc tttgccaaga
    16921 aagtttgcgt tacggaattt ctgttcaagc agaaatggta catcatatct ttcctgtgtc
    16981 tgaatatcct gagcttgaat ttgttgaatg gaattgcttg ccattgacga ataagaaaca
    17041 taatacgttt catgatagag tgaacgatag agtaatcaac caaggattgt attggcagaa
    17101 aaaaagaaaa aaagaatttt taaatttttt caaaaatgaa aaatgaaaat ttttaatccc
    17161 cccctctttt tgaaaaatca ttttggccag tagggtactg gtgaagggaa ctttttccaa
    17221 gtcgggggcc ttcaaacaaa aagggggtaa aaactaagcg attttgacga aaggaggtag
    17281 tttttggcta aaccaattac agcaaagtcg attaagtcaa aagtggtcaa gcagatgaaa
    17341 gacttgggaa cttatcgtaa agagttcgaa atgatcattg acatttttgc aggtatgtta
    17401 taccagtatc agaaacttgc tcaagattat gctgatatgg gttatccagt aacagacacc
    17461 tacgtcaata aggctggtgc tgaaaatgag cgcaaagttc caatcttgac agcgatggaa
    17521 attttgagga aagatatact cagctactct aatcagttga tgatgaatcc taagtcgctc
    17581 ggtgaggtag tagaacaaga gggtgagtca gttcttactg aggtactgaa gttcaagaac
    17641 gaaatcaaga agaagcgagt gactggcaat gggtaatctt gataaagcta aaaaatacgc
    17701 tcaacacgtc ttaactcacc gagaagaaca ttgcgaagaa aacatccttg ctgctgaacg
    17761 ttttttccgt gatttagaaa atccaacctt tgagatggat gaggatatgg tggattttgt
    17821 tattcacttt atcgagaacg tgatagttca tcagcagggc gatgatatgt ttgcggtatc
    17881 tatccgtaac aagccattgc ttttgcaacc gtggcaacat ttcgttgtag ttaatctgtt
    17941 tggtttttac tacaagggta cgaatgagcg caggttcaaa gaagcgctta tcatgcttgc
    18001 tcggaagaat gggaagacct cgtttactgc tgcaatcgca cttgcttatc agatattaga
    18061 tacagatagc ggttccaaat gctatatcgt tgctaactca gtcaagcaag cgatggaagc
    18121 ttttggtttt ttaagattca acgttgaacg ctggaacgat aagaacattc gtatcaagga
    18181 taataaccaa gaacactcta tcaccgccaa ttttggtgat gaaggttctt tctttatcca
    18241 ggctttagcg aatgatgaga gccgtctgga ctctttgaac ggaaatgtta tcatcttgga
    18301 cgaagctcac acaatgagga acagtaagaa acatggtctt atgaaaaaaa caatgtcagc
    18361 atacagaaac agtatgcttt ttgttatctc aacggctggg gatattccta ccgggttcct
    18421 tgctaaccgt ctgaaatact gtcaaaaggt gctcaagcaa ttagtcactg atgattcatt
    18481 tttcatcttc atctgcaagg ctaatcaatc tgctgatggg gacgtggtga actatctgga
    18541 cgagaatatc ctcaagatgg ctaatccgtc atggggtgtc acggtttcgc tcaaggctct
    18601 caaggaagaa gcagagcagg ctatgaatga tcctcagaca agaaatgagt ttttcaataa
    18661 gaccttgaat atcttcacta actctatgaa cgcttatttt aatcctgatg agtttattgc
    18721 gtcggatagt tgctacgatt ggagtttaga agagctggca cgtttgccta ttcgttggta
    18781 tggtggtgcg gacttgtcaa gattgcacga cttaacagct gctgctctct atggtgtcta
    18841 tcatgacggt gagaaagacg ttgatatctg tatcacacat gctttcttcc ctcggattaa
    18901 tgctcagaaa aaagctaatg atgacgggat tccactcttt gggtggcagt ctgacggttg
    18961 gttgacgatg agcaacactc cgaccgtcct ctatgatgat atcgtcaaat ggttcatcaa
    19021 gatgagggag aaagggttca agattgctgc tgtcggaatg gataggaagt ttggccgtga
    19081 gttcttgacg aagatgaaac aagctcggtt caagatgatt gaccaacctc agctttttta
    19141 tctgaaatca gagggattca gacggattga gtttaaagtt aagaataaag aattttacta
    19201 tcttcattct gatgcttacg aatactgtgt gagcaatgtt agagcaattg aaaaggtgga
    19261 cgatgctgtg caatatgaga aattagatgg agacggtggg actgcaagga ttgacttgtt
    19321 tgatgccagc gtctttgctt gtatacaggc tcttgctaat cttggcaagg gtggtgatgt
    19381 gatgagattc tttgattagg tgaattatga atgaaatagt attatcagaa catgaaatta
    19441 acttgctgat caacaaaggg cgagttaaag taattttaaa cggggaagta gtaactattc
    19501 gtcaaagaca tatgaaaaat ttgatggctg aaacagtaaa atgggaaaaa caggtaattg
    19561 atgtcagtca gaatatcgta agaaataaac actttgattc actttttcaa aatacttttc
    19621 gttagaaagg aggtgaggaa acatgggtat ttttgaaaag ttttggaaac gaaacaagcc
    19681 aagtaagtca atcaacatgc tgagtcattc agatttaggg ttgtcaaacc tgatggactc
    19741 gtatgtacct ttggccagaa atccagatgt ggtgacagcg gttaataaga ttgctgattt
    19801 ggtctctaat atgaccatcc acttgatgga gaatacagat aaaggtgata tcagaatccg
    19861 tgatgggctt gctagaaaga ttgatatcaa tccgtgtaaa cacatgacaa ggaagtcatg
    19921 gattttcaag attgtgcgcg atttgctttt atatggcgat gggaactctg tcctacatgt
    19981 ggaatatgaa cctgttacgg attatatttc taatctaaga ccatttccga tgagagaggt
    20041 ttcattccaa acagataagg attcctatgt aatctcattt aggggtgaag aatattcccc
    20101 tgatgaagta gtccacttcg tcatcaatcc agatccagat attccataca ttggtactgg
    20161 ttttagggtg acgttgacag atgtggttca aagtttgaac atggctacca agactaaaaa
    20221 aagctttatg aacgggaaga atattcctag tcttatcgtt aaagtagact cgtctagtgc
    20281 tgaactagat tcggagcaag ggcgtgagcg tatcgctgag aagtatttga gtactagcag
    20341 ggttggcgct ccatggattg ttccagaggc attgctggac attcagcagg taaaaccgct
    20401 tagtctaacg gacatcgctt taaacgagtc tgtggaattg gataaaagaa cagttgcagg
    20461 tctattagga gtacctgctt ttattttggg tgtaggagag ttcaacaaga cagagtataa
    20521 caactttgta aatacgactg tcatgagtat tgctaccact attactcaaa cactaaccag
    20581 ggacttactt ttgtctagca atcgttactt caagctaaat cctcgttcac tcttctctta
    20641 caacattacg gagttgtctg ctgttgctca acaaatggca aacagtgctg caatgcgtcg
    20701 taatgagtgg agggattggc tagggatggc tcctgatcct gagatggaag agttgattgt
    20761 tcttgaaaac tttctccctc aggagaaact aggagatcaa aataaactga agggaggtga
    20821 ggaagagaat gcaaaagcga aatagctatc gtgccactca atttcaaacg agagaagaag
    20881 aatctggtga tttgattttg agtggctact ttatcaagtt tgacgaggag acggaattgt
    20941 ggccaggcta ctgtgaagtt atcaagcgtg ctggtgttga gaaagctgtc acagacgctg
    21001 atatcagagc tttatttaac catgatgata gccttgttct cggtcgaaca ggtaacggaa
    21061 ctctgacact gggtgttgat gatgttggtc tttttggaga tatcatcatt aacaaggatg
    21121 atcctcaagc tgttggggcc tatgcccgtg tcaagcgtgg agatgttata gggtgtagct
    21181 ttggctttat cccggtaaaa atcgaaacgg aagaacgtga agatggttca tatttggaca
    21241 ctgtcttaga gctagaaatc tttgaagtga gtccatgtac tttcccagcc tatccacaaa
    21301 cggaaattgc tgcacgacaa aaagacttcg aaagtcagaa gcgtgctaat cgtgaagcgc
    21361 tagacaagcg caagaaagaa attaaggaga aatttaatct atgaacaaat tattgatttt
    21421 gggcgctcgt atgcgcaaca aagcagacaa agttgtagag cttgaagaat caatcaaaga
    21481 attgaacaag cgttctgaac ttgaagctaa gaaattggaa caagctggaa ctgacgaaga
    21541 agtttcagca gttgaaaaga accttgaaga catccaaaaa gaatcggatg aaaaggaagc
    21601 agaaaaagaa caacttgaaa aagaaatcga agatttgaaa aatcaagttg aagaactaaa
    21661 tcgtaaagca ccgacttacc caagtcaaga aaaacgtgga ggacagaaat tggaacgacg
    21721 tgacgcaatc gctaaataca ttcgtactgg tcaaactcgt gacattgtag gcttgaaaac
    21781 tactgattca ggaagcgcag ctttaatccc tactgaagtt ttgaaacctc attttgttaa
    21841 taaaacacgt aatccacttt tggatcttgt ggaacgtgtg aaagttaata gtggatctgg
    21901 taaatatcca gttatcaaga aaacgaatgg tgtaatggtt tcaatagatg aattgaaatc
    21961 aaatccagaa ctcggaaaac cagcaatcag cgagattgat tattcaatca agacttaccg
    22021 tggatatgtc cctgtgtcac aagaaatgat tgacgacgca gactatgaca tcatgtccat
    22081 tgttgaagac gaagtgttca atcaaggtga caacactgaa ttgtcattag ttacagctgt
    22141 cctcaaaaca gctacccaag cagatgcggc tggatttgat ggtattaaag atatctacaa
    22201 caagaagctt aaatcaattt ataaagcaag catcgttgta actaagtcaa tgtttgctgc
    22261 gcttgacaaa gtgaaggaca aagatgggcg ctacatgctt caaactgatg tggcttcacc
    22321 tactggctat tcatttggtg ggaaaacaat ctacaaagta gatgacacag tgtttggaaa
    22381 cgaaggagat atgaaattct tcatcggaga tgttactgag ttcgtcaaag agtttgaccg
    22441 ttctcaagta tccgttaaat gggtgaacaa tgacatttac ggacaattgc ttgggctttt
    22501 tatccgtttg gatattaaga aagcagatga agaagctgga ttcttcggaa catatactga
    22561 tgttgtagct taaggaggta gcgtatgagc tataaagtaa tccgtccttt caaggacttg
    22621 gctgatcctg aaaatcatga ctacgctgtt ggcgatatct ttcctcgtga gggatatgag
    22681 ccaacagata gctttaccaa tggccttttg actggcgcta acactgctgg ctctatcttc
    22741 cttgaggttt tgggagatga tgaacctaag aaaccagcgc ctgaaacaaa agaagtgaag
    22801 gaagagcccg cagttgagca ggaagaaaca gttgaggaaa ctgctgaaga gtctgctgag
    22861 gaagttgagg aatagacatg gaccaaggtc agcttttaga gttgctgaag cttaagttgg
    22921 gtatttcaac cgacttgaga gacaagccgt taaaaaaaat catttcaagt gtcatcactg
    22981 aattgaccga taatctcggt atcgagcttg ttggtgagcg tgctgaccat gaaatgttta
    23041 tcgttgacta tgccgcttat cgttatgagg gtggggtgga tatgccacgt caccttcagt
    23101 ggcgactgca taatttacag atagcatcaa agaaagaggt caagaatgtg gaatcatgaa
    23161 atcacactga tctccaagaa agtaacaggt aaggataagt tactacaacc aatctctgaa
    23221 gatgttgaag ttactctctt atgtcgcaaa aagagggtca ctcgctctga attttatcag
    23281 gcgaatcagg tagggcttaa accgagcttg gtcgttgaga ttcgaaattt tgagtatgag
    23341 aatcaagagc ttgcgaagtt cgaaggcaag caatatcata tcttgaaaac ctatcctatt
    23401 gattctgaaa ttttagagtt gactttgtca gaggtgttga aatgagtaat gaccttgctg
    23461 atttgatagc gaaagagctt gcagcttact ctgatgaggt tactgaagaa gtggataaga
    23521 ttgcagagca agtgactgat gagactgtgg atgagttgaa agagacaagt ccgaaacggt
    23581 acggaaagta tcgtagaagt tggaaaaaga agaagttggc caatggctct tttgttgtgt
    23641 tcaacgcagt tgcaagtctt actcacatac ttgaaaacgg gcacctttca agaaatggtg
    23701 gtcgtgtcgc tggtatcgtc cacatcaagc cagctgaaga aaaagcaatt cagaactttg
    23761 agaagcgaat caaggagatt gggaaatgaa gctatcagac tttgctgcta ttttggaaca
    23821 ggcaaacttg cctgtcactt atcgagcgtt taaaattgga aacgctcctg acctacctta
    23881 tctggtctat tatgaatcaa gtccagtcat caattcagct gacaacacgg ttaatcatca
    23941 gattaagagc gtgacagttg agctggcttt tgagagtaag gatgaagatt tggaagaacg
    24001 tctggaagag ctgtgggcaa accacaagct cttttttgaa gttcaagaag aaacatttat
    24061 cgagactgaa agactctatg tcaagtctta cacagtctat ctatactaag gaggaatgac
    24121 atgactcaag aaaataaagt aacctttggc ctagaaaatg tacatatcgc acctatcaag
    24181 acacttgcag cagatggagt tatcacttac ggcgatgttt ttcgttttcc tggagcaata
    24241 gagctgatac ttgatactaa aggggaaaca acccctatca aagcagacaa caaggattac
    24301 catttcatga attcaaacga aggatatgag ggtaaactta aaatcccaca catcattgat
    24361 gaatttgcga caaaaattct tggtgaaatc aaggaccctc aaactggtgt tatgactgaa
    24421 aaagcagatg cgagcttgac agagttcgca atgatgttcc agtttgaagg cgacaaaaac
    24481 aagactcgct atgtgatgta ctactgtttt gccagtcgcc catctcttgg ctcaaaaact
    24541 aagaacggga catcaaccaa cgaacgtgaa cttagtttca aagctagccc gcgtccattg
    24601 gatacagttg tcaagcgttc tatcacatca gctgatgaca aggatgcgta tgacaactgg
    24661 ttcaagaaag tgtatgaacc tactgcagtt gcagcttaag gagaagatct atgcgtaaaa
    24721 tcgttttggt tggtgatcag gagtatgagt tggggaccaa cggctatact cctattgctt
    24781 acaagcaaca atttggaaaa gattattttc aagatttgtt ctcgatgttg aaaaatcaat
    24841 cattcatgaa tgaattgaac aagttggaaa ccgacaagga attgacagcg actaatattg
    24901 atatttcgat gttgtcagat tttgacatga cctttttcaa ccgtcttttt tggacctttg
    24961 ctaaatctgc aaatcctcac atcaagcctt atgaacaatt cttcatggaa atggaaatct
    25021 tcccgattca ggaagttgga cctgtgctga tggaaatgct aaatgcgagc atgacgacaa
    25081 aaaagcacca gatgagtcag aatcagctag cgaagaaatc ttcacagtag aatcctatct
    25141 atcttgctgt aaagaaactg gtctttctat tgatgatcta aagcacattt caatcggaat
    25201 ggctctggat tatcagacgg attatgtgaa tctacggagc gaggataagg gtggcgaacg
    25261 gaaagccacg caagctgatt ttgacagttt ttaaagaaaa atgagtgctg agagagcgat
    25321 tctgagacca agttccttgg tctggctgca ttatcagtgg tagaagttct ctcagcgctt
    25381 ttctattttt ttgagaaagg aggaaatatg gcaggaaata tcaaaggtat caaaattgaa
    25441 atcgatggcg acacgcaacc cttgcagaag gcgctgaaaa atgtcaataa ggccgctact
    25501 gatgcaagtc aggagttgag acagattgac aaggccttga aatttgatac agggaacgta
    25561 acgctcctga ctcagaaaca agaggtctta caaaagcaag tttcgacgac caaggagaaa
    25621 ctggaaacct tgagacaagc tcagtctcag gtggaacagc agttcaaaaa tggtgatatc
    25681 ggtgctgatc agtaccgtgc ctttcaacgc gaagtcgaag ttactcaaaa cgtcctaaaa
    25741 ggatatgagg gtaagcttgc aaatgtgaat caggcgctta atgagaatgg gagtgctact
    25801 cagaacaaca agaaccaatt aaaagagttg caaaatgagc agagtcaact tgcttcagag
    25861 atgagtaagg tgacaagttc attcaaactg caagaaagcg ctttgggttc aaatgctagt
    25921 gaagccgaga gaaatgctct tgcccagaaa aagattggtg cccagtctga gattgtaagt
    25981 aaacagattt caaatctaga acagcaattg gaaatcacta aaaaagaatt tggtgagaac
    26041 tccacacaag ccaacaagat ggaatctgag ctaaatcagg ctaagactgc ttttaatcat
    26101 ctcaatgatg agatgaaggg aacaaagtct gctgctgata gcactcaaga aagtttaagt
    26161 gaaatctcaa gaaatttaag agcagaacta cttcaacagt ttagtgagaa gttgagtgct
    26221 atttcagaaa agcttgtgga agtaggaaaa gaagcgttag aagcagctgc tcaaatgcaa
    26281 gctagtaatg ctcaatttac taccgttttc ggagatatgg aaacccaagc aagagaagcg
    26341 ttgaatgcta ttggtcagga aatggatatt gtcccagagc gtttacaagg gtcatttact
    26401 cagatggctt catttgctaa aacttcagga ctagacactg cgcaagcatt ggacctgact
    26461 tcccgtgcaa ctagggcagc ggcggatggc gcagcttttt acgacaagtc catcgagagc
    26521 gtatcagaaa gcctacaatc tttcctgaaa ggaaactttg ctaacgatgc cgctcttgga
    26581 atctctgcga cagaaacgac caggaatgca gctgcaaata aattgtacgg aaagtcattc
    26641 aaggacttga gcgaagcgca gaagcaattg accttgcttc agatggtcga agacggaaat
    26701 aaactctcag gagctcttgg acaggctgca agagaatcag acggcctaga aaacgtgatg
    26761 gggaatctga aacaagctgg gaccaatgca ttatctgcta ttggtcaacc tcttctagaa
    26821 atgatgattc ctgtttttca aaccttggca acgattgtga aaggtgtggc cgagctgttc
    26881 aattccttgc ctgatccagt aaaagatttt gttgttattt taggaacagt tgtgactgct
    26941 gtaggggtca tagcccccat attcttaacc ttgcaagccc ttgctgagtt tttaaaaata
    27001 tctattggag aaatgataat tgccgcattg ccaattattg gaacagctat tgcaattgct
    27061 gctgcagttg ctgcaattat tgttattgta aaatatctct gggaaactaa cgaaggtttt
    27121 cgagatgcgg tcacgaccgt ttggaatgct atactagccg ttatcaatac agttgtttca
    27181 gaaatctctg atttcatcat gagtatattc gggacggttg ttacttggtg gacggagaac
    27241 caggaactta tcaggacaag tgctgagact gtctggaatg ccatttatac ggtcatcagt
    27301 acaatactgg atatacttgg ccccttgctc caagctggct gggataacat tcaactgatc
    27361 attacaacaa cttgggaaat catcaagatc gttgttgaga ctgcaatcaa tgttgtcctt
    27421 ggtgttatcc aagcagttat gcagatcatt actggtgatt ggtcaggagc ttgggaaact
    27481 atcaagggag tgttttctac tgtatggcaa gctattcaaa gcattgttca gactattttc
    27541 tcagctatcc agagttatat ttcaaatatt ctcaacggca tttcaggaac tgtatcaaat
    27601 atctggaaca gcatcaagga cactgtctca aatgtgttaa atgctatatc tagtactgta
    27661 tcaagtgttt gggaaggtat caagagtacc atttcaagtg ctatcaatgg tgcaagggat
    27721 gctgtttctt cagctattga agccatcaaa ggattgttta acttcaacat cagctggcca
    27781 catatcccac tacctcactt ttacgtgagt ggttcggcca atccattaga ttggttgagt
    27841 caaggtgttc caagtattgg aatcgaatgg tatgccaaag gcggtatcat gacgaaacca
    27901 actatctttg gaatgaatgg taataacata atggttggtg gtgaagctgg gaatgaagca
    27961 gtattgccac ttaacgacaa aacgcttgga gccatcggtc gaggtatcgc tcaaactatg
    28021 ggtggaactt caccaaccat caacattact attactggta acaccgtcag agaagaagct
    28081 gacatcagtc ggattgctga tgaggtggct cagcgtattg ctgacgaatt acaacgtagg
    28141 agacaattga gaggagggtt tgcatgataa agcataatga gcttgtgatt gacggtgtga
    28201 ggacatcgtc ttttccattt aagatcattg tccatgactc tccttcaatc gctctaggag
    28261 agagcaagac agctctcttg gagcatggtg gtgtcagtgg ggcaatcgtt cagacaaaca
    28321 agcataggga actggtcaag aaaacttata cgatttactt ggtcaaacct actgaagaac
    28381 agatgaacca atttatgagt ctgtttatcc gtgaaaagtt ctggctagag agtgagcgag
    28441 tcaaaacaac tcgtctttgg tgctataagg tcaatgtgag cgaccttgaa gaagtgcaac
    28501 ctggtcttta catgaccaaa gcaaccttca cttgccatcc tacaaaatac tttaaagact
    28561 ccgatacaca gagattgaca agaagtggga ctttgaccgt tcaaggttct gctcttgcct
    28621 ttcctaaaat cacaatcgtt ggtcagagcg cttctgaaac ttcatttaca attgctggtc
    28681 aggtcattcg tcttgaacga ctcactgagt cgcttgtgat ggttaataat cctgacaatc
    28741 caagttttaa aacaacaaca gggaagccag tcaaatggtc aggggatttt atcacagttg
    28801 atccagcgaa agtgaagaat attggggttg ttttaggccc aggtattcaa tcgattgaaa
    28861 tcgaaacggt ttgggggtgg gcataattgc tttatctact taataaagat gtaagaaccg
    28921 ttcgatggaa cggggagcca cttcatgaag cgacttcggc gattgtgaaa gaaactatga
    28981 atggcgattt taccttgact gtgaaatatc ctatttctga ttctggtatt taccagctca
    29041 tccaagaaga tatgctgata aaggctccga ctcctgtctt aggagcgcag ctatttcgta
    29101 tcaagaaacc tgttgagcac aatgaccatc tggaaatcac agcctatcac atttcagatg
    29161 atgtgatgca acgatctatc acacaaatga gtgtgactag tcagagttgt ggcatggctc
    29221 ttgctcgcat ggtacaaaac accaaaacgg ctcttggaga cttctcattc aacagtgata
    29281 tccaggaccg taggacattc aacacgactg agacagaaac cctgtactct gtattgctgg
    29341 acggcaagca tagtatcgcc ggaacgtggg aaggcgagct ggtgcgtgat aactttgcga
    29401 tgactgtaaa gaagagtcgt ggtgagaatc gtggtgttgt tattacaaca cataagaatc
    29461 tgaaggacta ccaacgaacc aaaaacagtc aaaatgttgt tacaaggatt catgctcgat
    29521 ccacatttaa gcctgaaggt gctgaaaagg aaacaactat cagagtgact gttgatagtc
    29581 ctcttattaa ttcttatcct tatataaacg aaaaagagta tgagaacaac aacgcaaaat
    29641 ccgttgaaga gttgcagaag tgggcacagt ctaagttctc aaatgaggga attgacaagg
    29701 tctctgatgc tatcaaaatt gaagcttatg aacttgatgg gcaagtggtc catatgggcg
    29761 acacggtcaa tctcaagagc tggaaacata atgtcgatgc attcaagaaa gctattgctt
    29821 atgagttcga tgccttaaaa gaagaataca tctctctgac tttcgatgat aaggcaggta
    29881 ttggtggttc tagatcttct ggtggcctat ctagcgcagc cgatgcaatt cttggagtga
    29941 cagaatctgc acaagaaatc gcccttgaaa aggctcttca aaatgctgac ttagactttg
    30001 atcataaggc tggattgctt agacaggaaa tttctgacga tattgaactg gccaaagcca
    30061 gagctgaaga agtcaagaga gaactgtctg acactatcaa tcagcgattt aatagctttg
    30121 acaacgggcc attgaaagaa actaagcgca aggctgagga agctttgcga aatgctggcg
    30181 caagtaccct gcttgcacag gaagctaagc ggattgggct ggattctgtc gctagacttg
    30241 aagcgtttaa gtcgcagact acgagcgcac aaacggctct gtcgggtgac ttggacgctc
    30301 tgaaacggac tatcgcgaat gatattcgac cgaagcaagc acaggctgaa gctgagattg
    30361 ccaagcaagc tgaagcactt agccggacta aaaatgaact ggctggcgca agtaccctac
    30421 ttgcacagga agctaagcgg attgagctgg attctgttgc tagacttgaa gcgtttaagt
    30481 cgcagactac gagcgctcag acggctttgt caggtgactt ggatgttcta aaacaaacta
    30541 tcgcaaacga tattcgaccg aagcaagcac aggctgaagc tgagattgcc aagcaagttg
    30601 aagcacttag ccggactaag aatgaactgg ctggcgtgaa gtcagcgcaa gcgacgtata
    30661 aggagacgac gactcgtaga ctgtcagaac tgaccaactt ggccaatggt aaagccagca
    30721 agtcagaact tacgcaaaca gctgaggagc tggctagtcg gattgcgagt gtgcaggcag
    30781 gtagttcacg gaattacttc aggaattcac gttcaagaac gttcacaaca ggaggtcaag
    30841 cggtatacga ctatcgaaca ttcatagttc ctgatttctg gaagaacagt gacaggttca
    30901 agcgtgatta tgttcgcata tcttttgatg tgactttccc tgtcgcccta gtaaatgaca
    30961 tgcctgctat ggtgcatttt agtgctcatc catggtatgc ctacagaaac ttaattttta
    31021 aaggtggaac tgtcgaacgc caacattttg agtttacgat tgacttgtct agttcttctg
    31081 aggactatca gactaataat gtgttcattc gttttggtac taattatgga tttcctgctg
    31141 gtctgcaggt cgtcattgag aacgctatgt tatcggttgg taattatttt ccagcctatc
    31201 aaccagcgta tgaagaccaa gaagaccgtg tctcagtagt cgaatccaac tttaaacagc
    31261 gtgctgattc actcgacgct ggtgtaagaa gcttgactga aggccttaga accaaagcgg
    31321 atatcagctc actcaatgtg actgctgaaa atatccggca atctgtgaag agccttgaga
    31381 cagatacgca gaacaagcta aatcagaagt tgagtcaggc tgaatttgag gtgcgagccg
    31441 gctctatccg tcaggaaatc ctgaacgcaa ccaaggataa agccagcaag tcagaactca
    31501 cgcagacagc tgaggagctg gctagtcgga ttgcgagtgt gcaggcatcc ggtcgaaatc
    31561 tattcttgaa ctcactattc aagcaggata ttccaaaaac aggaatttgg acaacgagta
    31621 catatacggc tactatcgat agcgaaagta agtatcttgg acacaaggct cttaaaatta
    31681 taggtttgaa tccatctggc cgtgatggag gtaatcccaa ggttacttat ccagctctgg
    31741 gtcaattcgg gaaagtaatt cccggaagta cgactaatca agatgtaacc attagttttt
    31801 atgctaaggc aaataaaaat ggaataatgc taagatctcg attagggaat atcggatata
    31861 aaactggaaa tgtgacattg tcgacagaaa ttaagcgata tgttgtccat attccaaaag
    31921 gttggacaaa cgaatccaag cagaccacaa atgaatggtt gttcaatttc aaccaggaag
    31981 gaaccatttg gatttggatg ccgaagtttg aaataagcga tgtagatact tcttattcag
    32041 aagctcctga agatatagaa ggtcagattt caacagttga atcgaccttc aaacaacgag
    32101 ccaactaact cgacgctggt gtaagccgtc tgactgaagg ccttagaacc aaagtggata
    32161 tcagctcact caacgtgact gctgaaaata ttaggcagtc ggtgaagagt cttgagacag
    32221 acacgcagaa caagctaaat cagaagttga gtcaggctga atttgaggtg cgagcaagcg
    32281 gaatccgtca ggaaatcctg aatgcaacca aggacaaggc tgacaagacc ttggtaacag
    32341 cggaggctgg gaagttgaga gaggagctga caagtctgtc ggttggcgag aatctgtttg
    32401 taaactcaga ttttaaaaat ctgagggata acggacagcg ttatacagct aacggcaaga
    32461 cctatcaaaa catgattgcg ccttactggt acaatccgta caatgctggt attccaaatg
    32521 ctcaaaatat ccagcatggg tattttgaca cggaaacgtt tagtgatact gtctttgcct
    32581 ttaacgagag cgacggctcc cgacactgga aagcattgtc aactgatttt aaaatcggag
    32641 tcatctcagc tggagagtat tacttttcag ctgatttgta tgcgacagat ttaggcactc
    32701 atatcaaatt tggattttac tatcacaact cgactggcaa actcaatttt tacgcaggtc
    32761 gaacaaaaat tgaagttact gaaaaaggcc gttggactag gctaggaatt gacttaaagg
    32821 tcaatgatga cattgacctg acaaaaaaag tccaatttta catttacggc tataattttg
    32881 ctagcaactc aattttgtac cttaaaaagc ctaaagtctc gaaaggtcgc ttaaaaagcg
    32941 attggagccc agctctggaa gacaccgaag gcctcatcac tgaggctaag gcaacctttg
    33001 agcggacagc tcagggcttg cgaaccgact tatcagctat tcaggaatat gtaaataaag
    33061 acggtcagcg acaggaagcc ctacagcgct atactcgtga ggagagcacg agacaagcga
    33121 cagcagtccg tgagctggtc aatcgtgatt tcgttggtaa ggctacttat caagaagatg
    33181 ttaagggtat caatcagagg attgaagctg ttaaaactag tgcgaataaa gacatcgcta
    33241 gtcaaatcgc tagctatcgt caatctgtag atggtaagtt cacggatatt tcaagtcaga
    33301 taactactta taagcaagat gtgggcggtc aaatcagtgg tctatcaaat agacttacaa
    33361 gcagtgagca aggaaccact actcagattt caaatatttc aaatcggata aacagtaata
    33421 aacaaggcac agataatcag atttcaaatt taaagactca ggtcgctaca aacaaggata
    33481 atgctgaacg acaaatgggt agaatatctg atcaggtttc tgcaaacaaa gcgaatgctg
    33541 atagtcaatt tgcgaatgtg accaatcaac tagcgcgaaa agtagagact actgacttcc
    33601 agcgtgttaa ggaaaccagt aaactttacg agcggatttt gggcaatact gaaaatggaa
    33661 ttgcggataa ggttgctcgc atggctctga ccaatcaact gtttcaggtt taggttggga
    33721 aatatagtgt aagcggccct aacctcatta agaatagtga ttttaaaaat ggtacgaatg
    33781 aatggggctc aactcaaaat ttaggaagat tggttaagca tagcttttat cacaacgggc
    33841 agaaagacct tatgcgttta agtaatgcaa ctaaaaacga aaactttttg tatagtcacc
    33901 gttttaatct tgaacgaaat actgactatg tactgaattt tagaggattt aacaacagtg
    33961 ctctcgcaag ctatgatgtt tatattttgg gacgaagagc aggcgagagc gatggattca
    34021 caatcgttaa gaaagttgtt agcagcaaga aactatctac ctctagatgc gaagatgtct
    34081 cagtaacttt taattccgga gaaatggata atgcttacat tcgttttgat aacaatggct
    34141 catcatcagg aacagctgat ttgtatatta cagaagttga cttgtacaaa ggttataaac
    34201 ctagaacatg gcaaccacat ccagaagatg cagtcgcaga tgcgaataag aagcttgaag
    34261 ccacgcaaac aaaaatgact caactagctg gctcatgggt agttgaaaac atcaactcgg
    34321 ctggagatat catctctgga atcaatcttg gcgccaatgg acataaccgc tttgttggga
    34381 aattgaccca catcactgga gagaccctga ttgacagagc agtcatcaag tctgccatgg
    34441 ttgataagct caaaacggcc aattttgaag ctggttcggt cacgactacg atattagacg
    34501 ctgaagcggt cacggctgat aaagtgagat ttgatgctgc gtttattaga aaaatgattg
    34561 caaatgacgc ttttattgac caactgacat ctaaacgtat cttctctact aaggttgagt
    34621 ccgtcatttc tagttcaacc ttcctagaag cctatcaagg ccgaatcggt ggatttacac
    34681 ttggtcaatt tgatcagggt ggcggtcgct ggatttcagg tgtcaatcag ttctctgttg
    34741 gtatggggaa tggtgccggg catggggtgc cggacagcct tctgggcgaa ctggggaaat
    34801 aattggaact atgccggacc taaagcatgg aacgtcaata ctgatgggaa aatgtactgt
    34861 aggaatgaag tcggttttta tgatcaagtg gatttttcga attcatcgag agcaaacttc
    34921 tatgggaata ctactttttc tcgttctcct gtgttttcaa atggtatcga acttggaagt
    34981 aaagatgtgc ttggtgatgg ttggaatccc aaaggcggaa ggaatgcggt tgtttggtgg
    35041 aatcaggtcg gtagcggtag cgtgaagtat tggatggaac aaaaatcaga cagacgctta
    35101 aaagagaaca tcacagatac agctgtgaaa gccttggaca aaatcaacag attaagaatg
    35161 gttgcatttg atttcatcga aaataagaaa cacgaggaga ttggtctaat agctcaagag
    35221 gctgaaacca tcgttccaag aattgtctca cgagatcctg agaatccaga tggctatcta
    35281 catatcgact ataccgcttt agttccttac ttaatcaagg ctattcaaga attaaatcaa
    35341 aaaatagaaa aaatggagaa aacaatagca tgaataacaa catgttgacc aatatcgcac
    35401 ttaaagcaat tcaggagttt gctcttgaaa atagaaaacg aacacacaga ttggagaact
    35461 tagaaaatga acacagaaca gcttaaccaa gccttacaaa tgacaattcg tgaaatgtca
    35521 acaacttcaa cagattcgat gattgcaagt aatttcttga gtattcagtt gaatgagcaa
    35581 agggaagaga atcaaagact tcaagcacga gtggatgagc tggaagctct gcttgatgaa
    35641 caaactaaac cagcagacaa aggagaatag acatggcaga aacaattcaa aacacagata
    35701 acttactaga ccttacaaaa atcacagaac catttgatct tgcgagcgct ttgcgctaca
    35761 tgaaagaaaa tggagagttc attcgttgca agaatgtaag cgatgacttc tatatgtatc
    35821 gtgatgttca aaaacgtcct gtgatcgtaa atggccgtcg ccaattcaag gatgttgaaa
    35881 ctgtttgggc gttcaaccag tggggggggg tacaatcaca acaatcaacg tagccgttct
    35941 gttgaatcat gaattctata tcatgaaatt tgatgcagag ggcaatcctg actggacgga
    36001 tccaacggta aaacctaaag aataggaggt gtgtatgcaa attgaatttt tcaattttct
    36061 aagaagtgtc gtacagactg aagatggttt ggtcttgtac gctctagcac tgattgtctc
    36121 aatggaaatc attgattttg tgacagggac gattgcggcg attatcaatc ctgacatcga
    36181 gtacaagagc aaaatcggca ttaacgggct ccttcgtaag atttcagggg ttctcttact
    36241 gatgatcctc attccggcgt ccgttttgtt gcctgaaaag acaggttttg tattcttgca
    36301 ctcaatctat ctcgggtaca tcgcatttac ttttcaatct ctcattgaaa attaccgcaa
    36361 attaaaagga aatgttactc tttttcagcc gattgtaaaa gtatttcagc gattacttga
    36421 aaaagatgat gatacgaaaa aaggagaata acaaatgcaa caaattactg aaatcattac
    36481 taatggagca atcagcatcc tagtcatttt ggcaggggtg gtagttaggg tagtcaagga
    36541 atacctcgtc aaaaaaggtg gagaaaagac tatcaagatt gttgaaatct tggccaagaa
    36601 cgcagttaat gccgtggagc aggtagctgc tgaaactggc tacaagggag atgaaaaact
    36661 ggcacaggct cgcgctaaaa ttcgtgcaga gctgaccaaa tataatatca gtatgacgga
    36721 caaggacttg gacacctttg tggagtcagc cgtgaagcag atgaacgacg cttggaaagg
    36781 acaagagtaa tggatatcga tagaaacaga ctacgtacag gcttgcccca ggttggggtg
    36841 cagccttatc gacaagtaca tgctcactca acaggcaacc gtaactcaac cgctcaaaat
    36901 gaagctgatt accactatag aaaggaccct gaactagggt tcttttcaca tgttgtcgga
    36961 aacggccgca tcatgcaggt aggacctgtg aacaacggaa gttgggatgt tgggggcggt
    37021 tggaatgctg agagttatgc agcggttgaa ctgattgaaa gccattcaac taaggaagag
    37081 tttatggctg actatcgcct ctatatcgaa ttgctacgca atctagcaga tgaagcaggt
    37141 ttgccgaaaa cgcttgatac agggagttta gctggaatta aaacgcacga gtattgcacg
    37201 aataaccaac caaacaacca ctcagaccac gttgaccctt atccatatct tgcaagttgg
    37261 ggcattagcc gtgagcagtt taagcaagac atcgaaaacg gcttgagcgc tgcgacaggc
    37321 tggcagaaaa atggtactgg ctactggtac gtacactcag acggctctta tccaaaagac
    37381 aagtttgaga aaatcaacgg tacctggtat tatttcgatg gctcaggcta tatgctttca
    37441 gaccgctgga agaagcacac agacggtaat tggtactact ttgaccaatc aggcgaaatg
    37501 gccacaggct ggaagaaaat cgctgagaag tggtactatt ttgatgtaga aggtgccatg
    37561 aagacaggct gggtcaagta caaggacaca tggtactact tagacgctaa agaaggcgcc
    37621 atggtatcaa atgcctttat ccagtcagcg gacggaacag gttggtacta cctcaaacca
    37681 gacggaacac tggcagataa gccagacttc acagtagagc cagatggctt gattacagtt
    37741 aaataaatag aaaggaaact ttctaaattg ttctttcacc gcaggctcag gcttgcggtt
    37801 tttttgtttg tctgaatcaa gaaagcgtct aaccaaccga caccaatgtc ggtagcaaaa
    37861 taaatggttt gcctaaaaaa ttagagttaa gttctatttt tcaaaaacac gcattttgaa
    37921 cgattagaaa cagaaatcta aatcctattg ttcaaaaaaa cgtttacatg aaaaataggg
    37981 aggtgttttg ttaaaaataa aaacagtgat cgaaatcact gcttatcagt tgtagcaaat
    38041 tcataaagtt tttctgctgt gagaagtgcc attttgtcca tgcttgtttt tccttttctg
    38101 aggtcagaaa cagtagtcca tggaactcca gcaccttggg aaatagcaga tgtagacatc
    38161 gaactgtcta acaattcttg aataacttct ctcatcttat ttgtcctttt tattttttag
    38221 ataaatatat acattgattg caattataaa aatagctatt gcactaacca ttgcatttcc
    38281 tctttccatt tgataaaata gaggtgtaag gggctttcgc cccaacctct tagcgtttac
    38341 ctttttcttt gacgggattt cggtttacgc tttttgtttt gccttgcgac cgttattgcg
    38401 gtcactagac ttgcgatagc agttaccgtt tcaggaatat tgtctattgc cttttcaagt
    38461 aacctgagcc aatcttcttt gttcaacttc atcaccccct ttccttatct tgattatatt
    38521 atatcacggt acaccgagaa agtcaagcgt tttgatgaag ttttttttaa ttttttcaaa
    38581 aaaaaataga ccttgtccag aggtcgggga gttggagggg gcaccctcca aaagcattga
    38641 tttaataagg ttttatttta cctttttcat aataatctcc ctatagagtc accgcattcg
    38701 gtggcttttt ttgtgttggg attcatgata taataataaa atcgataagt aggaaaagag
    38761 aaaagagatg tattatacgc ttgaagaaaa agaagtcttt atgagggagg ctttgagaga
    38821 ggctgagatt gctcttgaac acgatgaaat tccaattggt tgtgtgattg tcaaagatgg
    38881 ggaaatcatt ggtcgtgggc ataatgcgcg tgaggaatta cagcgagcgg ttatgcatgc
    38941 ggaaattatg gctatagagg atgcgaactt gagtgaggag agctggcgct tgctggattg
    39001 cacacttttt gtgaccattg aaccttgtgt catgtgtagt ggagcgattg ggcttgcccg
    39061 cattccaaat gtggtctatg gggctaaaaa ccagaaattt ggcgctgctg ggagtttgta
    39121 caatatcttg acagatgagc gtctcaatca tcgtgtggag gttgaaatag gaattttgga
    39181 agatgaatgc gcagctatca tgcaggattt ttttagaaat agacggaaaa aataattttg
    39241 cttttaaaat gaataggaat gtgatataat aaatagtgga gcaacagttc tgcgtgaagc
    39301 gggtcagggg aggaatccag cagccctaag cgatttgaat tgtgtgctct ttttttcgtg
    39361 ctttttccga ataaataaga tagaataatc tagaataaat gataatagaa aagagaaaat
    39421 tatgaaaatt cgtggttttg aattggtttc gagttttaca gatgaaaatt tattgcccaa
    39481 gcgtgagaca gcgcatgcgg ctggttacga cttaaaggtt gctgtgcgta cagttgttgc
    39541 gccaggagag attgtcttgg ttccgacagg ggttaaggct tatatgcagc cgactgaggt
    39601 tctctacctc tatgatcgtt cttcaaatcc tcgtaagaag ggcttggttt taattaactc
    39661 agttggggtc attgatgggg attattatgg aaatcctgga aatgaagggc atatttttgc
    39721 gcagatgaag aatatcacag atcaagaggt tgttcttgaa gttggggaac gtattgtcca
    39781 ggctgttttt gctactttct taattgcaga tggagatgca gctgatggcg ttcgaactgg
    39841 tggatttgga tcgacagggc actagaatga agattatctt tgtacgtcat ggggagccag
    39901 attaccgtga gttagaggag cgttcttata taggatttgg gatagatttg gcacccttgt
    39961 ctgagatggg acggcagcaa gtccagaaat tgagcaaaaa tcctttactc tcgtcagctg
    40021 aaataatcgt atcttctgca gtcacaagag ctttagaaac ggcttcgtat gtggtctgtg
    40081 ctacgggtct tcctttaaga gtagagcctt tattacatga atggcaggtc tataaaacag
    40141 gaatagaaaa ctttgaaaca gctagaagac tgtttttaga aaacaagggg gagttgcttc
    40201 ctaatagtcc tattcaatat gagacagcta cggaaatgaa gtctcggttt ctagaatgta
    40261 tgtctaagta tcgagaacat cagactgtgg tagttgttgc tcatcgaatg ctcatgcgcc
    40321 agtttgtgcc aaatgagaag attgattttt gccaagtgat tgagtgtgag ttagagatat
    40381 agaaagaggt ttgtcatcgc aaagaaaaaa gcgacatttg tatgtcaaaa ttgtgggtat
    40441 aattccccta aatatctggg acgttgcccc aactgtgggt cttggtcttc ttttgtggaa
    40501 gaggttgagg ttgccgaggt caagaatgcg cgtgtgtcct tgacaggtga gaaaaccaag
    40561 cccatgaaac tagctgaggt gacttccatc aatgtcaatc gaaccaagac ggagatggag
    40621 gaattcaacc gtgtgcttgg aggcggagtg gtaccaggaa gtctcgtcct catcggtggg
    40681 gatcctggga ttgggaaatc aactcttctc ctacaagtct caacccagtt gtcccaagtg
    40741 gggacagttc tctatgtcag tggggaggag tctgcccagc agattaaatt acgtgcagag
    40801 cgcttaggtg atattgatag tgagttttat ctctatgcag agaccaatat gcagagtgtt
    40861 cgtgcagaag tggagcgtat ccagccagac ttcttcatta ttgactctat ccagaccatt
    40921 atgtctcctg agatttcagg ggtgcagggg tctgtttctc aggtgcgtga agtgaccgct
    40981 gaactcatgc agttggccaa gaccaataac attgccatct ttatcgtagg tcatgtgacc
    41041 aaagaaggaa ccttggctgg gcctcgtatg ttggagcata tggtggatac ggtgctttac
    41101 tttgaagggg agcgtcacca cacctttcgt attttgagag cggtcaaaaa tcgttttggt
    41161 tccactaatg agattgggat ttttgagatg cagtcgggcg gcttggttga ggtactcaat
    41221 ccgagtcaag ttttcctaga agagcgtttg gatggggcga ctggttcctc catcgttgta
    41281 accatggaag ggacgcgtcc gattttggcg gaggttcagg ctttagtaac accgaccatg
    41341 tttggaaatg ccaagcgtac tacgacagga cttgatttta accgtgctag cttgattatg
    41401 gctgttttgg aaaaacgggc agggcttctc ttgcaaaatc aggatgccta tctcaaatct
    41461 gctggtggtg ttaaattgga tgaacctgcc attgacttgg ctgttgcagt tgctattgct
    41521 tcgagctaca aagacaaacc aactaatcct caggaatgtt ttgtcggaga actgggcttg
    41581 acaggagaga ttcggcgcgt gaatcgtatt gagcaacgca tcaacgaagc tgctaaactg
    41641 ggctttacta agatttatgt acctaagaat tccttgacag gaatcactct gcctaaggaa
    41701 attcaggtca ttggcgtgac aacgattcag gaagttttga aaaaggtctt tgcataatcc
    41761 gtgacaaatt ctcttaaaaa tgataagata ggagaaatat ttgactatca aattttcaag
    41821 gagggaatcg tgtcgtattt tgaacagttt atgcaagcca atcaggctta tgttgcccta
    41881 catgggcagt taaatctgcc acttaaaccc aaaacaagag tagctattgt gacctgtatg
    41941 gactctcgtc tgcacgttgc gcaagctctg ggcttggcac ttggggatgc tcatatcttg
    42001 cggaatgcag gtggtcgagt gactgaagac atgattcgtt cgctagttat ttcccagcaa
    42061 caaatgggga caagagagat tgtggtattg caccatacag actgtggtgc tcagaccttt
    42121 gaaaatgaac cttttcagga gtatttaaaa gaggaattag gtgtagatgt gtcagaccag
    42181 gatttcttgc ccttccaaga tatagaagag agtgtacgcg aggatatgca actgcttatc
    42241 gagtctcccc taataccaga cgatgtcatt atctctggtg ccatttacaa tgttgataca
    42301 ggaagtatga cagtcgtaga attataaata cttcatttag aaagaaagtg tatgaagaaa
    42361 agcagtattt tattgctatg tattggttta cagtatgaaa ccatctacta tacggacggt
    42421 tcgaggtcag gtgcggaata tggactaatg ggaatttcta tctttctagc tctcttttac
    42481 atgattccgg ctctttattt tctcttccgt attgggaaaa atgggaattg ccaaagaagg
    42541 ttttgattct gtctttattg ggagggatgt tcctttcagg ctggttgtct agttttgcta
    42601 atacttatat ccatgattta ctgggggttc ttttcccaga tagtacattt ttaaatgcct
    42661 ttgaaagtgc tattgtggct cctttggtag aagaaccctt gaaattattg ccacttgttt
    42721 ttgttttggc tttgattcct gtgcgaaaat taaaatcttt gtttttactt ggaattgctt
    42781 ccggtttggg attccaaatg attgaggata ttggttatat tcgtacggat ttgccagagg
    42841 gctttgactt tactatttcg cgaattttag agcgtatcat ctcaggaatt gcctctcact
    42901 ggactttttc aggtctagct gtagtaggtg tttacttgct ttacagagcc tataaaggac
    42961 agaaggttgg caagaaacag ggccttattt ttctaggttt agccttggga actcacttct
    43021 tgtttaactc tccttttgtg gagttggaaa cagagttgcc tttagcgatt ccagtggtta
    43081 cggctattgc tctctatggt ttttatcatg cttattgctt tgttgagaaa cacaatgagt
    43141 tgatgaccta gaatattttt caaaagaatg atgcaagggt acaaatatgg tgcccttctt
    43201 ttatttttga ttgaaaaata gtgcaaaaag cgctacaatg gtagatggaa aatcttgtga
    43261 aaggcacaag ttatacatat ataccggagg aaatcatgtc tttttctgat ttaaagctgt
    43321 ttgccctttc ttctaataaa gaattggcag aacgtgtggc gcaggagatt gggatagagt
    43381 tggggaaatc aagtgttcgc caattttcag atggagagat tcaggtcaac attgaagaat
    43441 caatccgtgg gaaacacgtc tttatcttac aatcaactag ttcgcctgta aatgacaatc
    43501 tgcttgaaat tttgattatg gtagatgctt tgaagcgtgc gagtgcagaa tctgtcaatg
    43561 ttgtcatgcc ttactatggg tatgcacgtc aggatagaaa ggcgagagcg cgtgagccaa
    43621 tcacttcaaa acttgtcgca aatatgcttg aagtagctgg agtggatcgt ttattgacca
    43681 tcgacttgca tgctgcgcaa attcaaggat tctttgatat tcctgtggat catttgatgg
    43741 gtgctcctct gattgcagat tattttgagc gtcgtggtat ggttggttct gactatgtgg
    43801 ttgtcagccc ggaccatgga ggggtgactc gtgctcgtaa gttggcagaa tttttgaaaa
    43861 catctatcgc tattattgat aaacgtcgta gcgttgataa gatgaatact agtgaagtta
    43921 tgaatatcat cggtaaggtt gaaggcaaga cttgtatctt gattgatgat atgattgata
    43981 ccgctggaac gatttgtcat gcggcagatg ctcttgcgga agctggtgct gttgaagtct
    44041 atgcaagctg tacgcaccca gttctttctg gtcctgctac ggacaatatc caaaaatcag
    44101 ctattaagaa attggttgtt ttggatacca tctatctgcc agaagagcgt ttgattgata
    44161 agattgagca gatttcaatc gctcatctcc taggggatgc tatcgtacgt attcatgaaa
    44221 aacgaccact ttctccactt ttcgatattg agaaaaaaat ttaatgacca agcctgagat
    44281 gattctcagg ttttttcgtc ttttttccga ataaatagat agtagcggtg aatctagtaa
    44341 agctagattt aaaactgtga tataataaaa agagaagaaa tatgactgta cgtcatcaga
    44401 agtttcagcg accatcattt ttgaacagtg atagcacttg aatcgacgct ttctaaggag
    44461 aattctagta ggcataccag tcgtttcaag ataaggaatt ttagaaggtt tttgaaagtc
    44521 atatt
//
LOCUS       DAVBOU010000012        43429 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBOU010000012 DAVBOU010000000
VERSION     DAVBOU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.012"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ879_000714"
     tRNA            1..73
                     /locus_tag="VQ879_000714"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ879_000715"
     tRNA            87..160
                     /locus_tag="VQ879_000715"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ879_000716"
     tRNA            171..260
                     /locus_tag="VQ879_000716"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VQ879_000717"
     tRNA            271..344
                     /locus_tag="VQ879_000717"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VQ879_000718"
     tRNA            348..420
                     /locus_tag="VQ879_000718"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VQ879_000719"
     tRNA            440..510
                     /locus_tag="VQ879_000719"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VQ879_000720"
     tRNA            546..619
                     /locus_tag="VQ879_000720"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VQ879_000721"
     tRNA            626..713
                     /locus_tag="VQ879_000721"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /locus_tag="VQ879_000722"
     CDS             complement(839..1774)
                     /locus_tag="VQ879_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3142915.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VQ879_000723"
     CDS             complement(1771..2631)
                     /locus_tag="VQ879_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3142916.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VQ879_000724"
     CDS             2739..4901
                     /locus_tag="VQ879_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3142917.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4993..6252
                     /locus_tag="VQ879_000725"
     CDS             4993..6252
                     /locus_tag="VQ879_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3142918.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6266..7132
                     /locus_tag="VQ879_000726"
     CDS             6266..7132
                     /locus_tag="VQ879_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3142919.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7146..7979
                     /locus_tag="VQ879_000727"
     CDS             7146..7979
                     /locus_tag="VQ879_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3142920.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7980..8060
                     /locus_tag="VQ879_000728"
                     /pseudo
     CDS             7980..8060
                     /locus_tag="VQ879_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ879_000729"
     CDS             8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ879_000729"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3142921.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9917..11110
                     /locus_tag="VQ879_000730"
     CDS             9917..11110
                     /locus_tag="VQ879_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3142922.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11797..13776
                     /locus_tag="VQ879_000731"
     CDS             11797..13776
                     /locus_tag="VQ879_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3142923.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVEVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13843..15339
                     /locus_tag="VQ879_000732"
     CDS             13843..15339
                     /locus_tag="VQ879_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142924.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15339..16265
                     /locus_tag="VQ879_000733"
     CDS             15339..16265
                     /locus_tag="VQ879_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142925.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16274..17341
                     /locus_tag="VQ879_000734"
     CDS             16274..17341
                     /locus_tag="VQ879_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142926.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17352..18278
                     /locus_tag="VQ879_000735"
     CDS             17352..18278
                     /locus_tag="VQ879_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142927.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18769..19284
                     /locus_tag="VQ879_000736"
     CDS             18769..19284
                     /locus_tag="VQ879_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3142928.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            19306..19707
                     /locus_tag="VQ879_000737"
     CDS             19306..19707
                     /locus_tag="VQ879_000737"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142929.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19719..20596
                     /locus_tag="VQ879_000738"
                     /pseudo
     CDS             19719..20596
                     /locus_tag="VQ879_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20609..21412
                     /locus_tag="VQ879_000739"
     CDS             20609..21412
                     /locus_tag="VQ879_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3142930.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ879_000740"
     CDS             complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ879_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3142931.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22340..24307
                     /gene="treP"
                     /locus_tag="VQ879_000741"
     CDS             22340..24307
                     /gene="treP"
                     /locus_tag="VQ879_000741"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3142932.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24485..26110
                     /gene="treC"
                     /locus_tag="VQ879_000742"
     CDS             24485..26110
                     /gene="treC"
                     /locus_tag="VQ879_000742"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3142933.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26252..26500
                     /locus_tag="VQ879_000743"
     CDS             26252..26500
                     /locus_tag="VQ879_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3142934.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26707..27501
                     /gene="racE"
                     /locus_tag="VQ879_000744"
     CDS             26707..27501
                     /gene="racE"
                     /locus_tag="VQ879_000744"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3142935.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27498..28469
                     /locus_tag="VQ879_000745"
     CDS             27498..28469
                     /locus_tag="VQ879_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3142936.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28445..28966
                     /locus_tag="VQ879_000746"
     CDS             28445..28966
                     /locus_tag="VQ879_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3142937.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28963..29424
                     /locus_tag="VQ879_000747"
     CDS             28963..29424
                     /locus_tag="VQ879_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3142938.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29415..30155
                     /gene="xerD"
                     /locus_tag="VQ879_000748"
     CDS             29415..30155
                     /gene="xerD"
                     /locus_tag="VQ879_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3142939.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30155..30883
                     /locus_tag="VQ879_000749"
     CDS             30155..30883
                     /locus_tag="VQ879_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3142940.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30902..31471
                     /locus_tag="VQ879_000750"
     CDS             30902..31471
                     /locus_tag="VQ879_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3142941.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31458..32180
                     /locus_tag="VQ879_000751"
     CDS             31458..32180
                     /locus_tag="VQ879_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3142942.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32180..32422
                     /gene="yidD"
                     /locus_tag="VQ879_000752"
     CDS             32180..32422
                     /gene="yidD"
                     /locus_tag="VQ879_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3142943.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32647..33612)
                     /locus_tag="VQ879_000753"
     CDS             complement(32647..33612)
                     /locus_tag="VQ879_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3142944.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33708..34460)
                     /locus_tag="VQ879_000754"
     CDS             complement(33708..34460)
                     /locus_tag="VQ879_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3142945.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34457..35413)
                     /locus_tag="VQ879_000755"
     CDS             complement(34457..35413)
                     /locus_tag="VQ879_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3142946.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35403..36362)
                     /locus_tag="VQ879_000756"
     CDS             complement(35403..36362)
                     /locus_tag="VQ879_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3142947.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ879_000757"
     CDS             complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ879_000757"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3142948.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37888..38952
                     /gene="pepA"
                     /locus_tag="VQ879_000758"
     CDS             37888..38952
                     /gene="pepA"
                     /locus_tag="VQ879_000758"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3142949.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38974..39270
                     /locus_tag="VQ879_000759"
     CDS             38974..39270
                     /locus_tag="VQ879_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3142950.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39952..40395
                     /locus_tag="VQ879_000760"
     CDS             39952..40395
                     /locus_tag="VQ879_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3142951.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40399..41163
                     /locus_tag="VQ879_000761"
     CDS             40399..41163
                     /locus_tag="VQ879_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3142952.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            41178..41906
                     /locus_tag="VQ879_000762"
     CDS             41178..41906
                     /locus_tag="VQ879_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142953.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41899..43419
                     /locus_tag="VQ879_000763"
     CDS             41899..43419
                     /locus_tag="VQ879_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3142954.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12538 a         8074 c         9795 g        13022 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcacccgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag ttggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtctgt aactctcttt tttattttta gagccaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctta ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgggaaa gagcaaaata
     2341 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagctcctga ggaatacttt gaaacaccgg
     3601 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     4021 ttcctggcta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct attttatcat gatattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat gcgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggctcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccttg
     4501 tagcaatgat gggaaatttg ggctatgaac ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgtatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4921 ttagatttat tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4981 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5041 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5101 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     5161 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     5221 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     5281 atcgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     5341 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     5401 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     5461 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     5521 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     5581 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     5641 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5701 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5761 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5821 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5881 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5941 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcatg
     6001 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     6061 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     6121 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     6181 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     6241 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     6301 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     6361 agccttttac agttttacca actggacagg attgacttat aactacaaat ttgttggctt
     6421 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     6481 aatcattgcg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     6541 cttgaattct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     6601 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6661 gattggaaat gcccttcata ttgaattttt ccaaaccagt cttttaggga ctaagtgggg
     6721 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6781 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6841 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6901 tatggtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6961 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     7021 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     7081 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     7141 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     7201 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaacccacta
     7261 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     7321 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     7381 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     7441 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     7501 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     7561 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     7621 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7681 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7741 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7801 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7861 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7921 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7981 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     8041 ttgaggttgt ggatgaaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga
     8101 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     8161 cacagaggaa gagtttagct tgttgataat tctatgcaga aaacaagaaa gtagtacttt
     8221 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttt
     8281 atttatgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     8341 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     8401 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     8461 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
     8521 cagcttttgg tgattgggag gatgttaagc atttaggtga gaaatattat cttatgtttg
     8581 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
     8641 atgaagccag tgaatttaaa gctctctttt taaactggga taagttttgg ccagaaaacc
     8701 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
     8761 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
     8821 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
     8881 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
     8941 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
     9001 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
     9061 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
     9121 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
     9181 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
     9241 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
     9301 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
     9361 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
     9421 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
     9481 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
     9541 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
     9601 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
     9661 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
     9721 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
     9781 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
     9841 attgctaaaa aagtggtaca atataggaca gcttactatt atctgaatca gctgatttgg
     9901 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
     9961 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    10021 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    10081 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    10141 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    10201 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    10261 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    10321 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    10381 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    10441 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    10501 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    10561 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    10621 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    10681 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    10741 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    10801 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    10861 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    10921 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    10981 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    11041 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    11101 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    11161 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    11221 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    11281 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    11341 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    11401 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    11461 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    11521 atattgttat aatttaattt gaattccaaa atcacattgt ttcgtccgta tttcatttta
    11581 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    11641 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa atttgtgcca
    11701 acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga tataatggtt
    11761 gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg tgtatttgct
    11821 acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc ttcaaaatca
    11881 tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc agaaaccttg
    11941 gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg gattgatggt
    12001 ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga ttgggaagtc
    12061 tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg gtttacctct
    12121 gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt aaaacacgca
    12181 gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg cttggcagat
    12241 tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt tgatgattat
    12301 acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt gacctattct
    12361 attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt tgctaaacca
    12421 acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt gactgcaaaa
    12481 tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt ccacctagat
    12541 actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg taacttcact
    12601 agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc taaggttgca
    12661 gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc tggtctgggt
    12721 gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc agagaaagta
    12781 gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt tgctcttgat
    12841 cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc agttcgtaat
    12901 ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga tttagtcgct
    12961 gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga tgggcaggat
    13021 ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa agctttagaa
    13081 gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc atcaaaaaac
    13141 tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg tgttgaaaat
    13201 gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac ttactatgct
    13261 gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg gccagactat
    13321 caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac tacaaaaaca
    13381 tatttaggat ttgataatcc aaatagccct tcagtagttg aagttggttt gaaagaatac
    13441 gataaattag ttgatgaagc tgccagagag acaagcgact tgaatgtccg ttatgaaaaa
    13501 tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc tatggcttct
    13561 tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc tgcgcaaaca
    13621 ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa agtggtgact
    13681 aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga atcaaatgag
    13741 aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag aactttctct
    13801 ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa atatattttt
    13861 atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac ctacacgatt
    13921 atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta taataaaatt
    13981 gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg tatgggctac
    14041 attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga ttcttctgta
    14101 acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa tcaattaggt
    14161 catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac tcgtgaaatt
    14221 ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga ccatacaaat
    14281 aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga aaatgatcca
    14341 gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt gtactttaac
    14401 agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga ctcttaccca
    14461 acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca aaccaaaact
    14521 gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta ctcaagaacc
    14581 tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa agatgatcct
    14641 tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc tgctattact
    14701 ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc agccatggct
    14761 cgtttcaaga acacttggat tgatagcctc tcaacagggg ctttgacctt cttgcttgct
    14821 cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat tgcccttcca
    14881 gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc agcagtcatc
    14941 cttggtttgt tgggtgctcc tggtacagcc atttggattc gtcgttacat gattgacttg
    15001 caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa agaaatttca
    15061 aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc tggtgccatt
    15121 attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc aggtatgggt
    15181 aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg tcttgtcttc
    15241 atctttacat gtatttctat cttctcacgt cttttgggag atatttggat gactattatt
    15301 gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc gataaagaaa
    15361 aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg ccagcatatt
    15421 cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta gtcatgttgg
    15481 gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct aagtttgatt
    15541 tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca aatgcggagc
    15601 attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg ttcggagctc
    15661 gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc ggtgtttttg
    15721 tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa gtttacaacg
    15781 tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca atcggagctg
    15841 gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt gccttcatga
    15901 tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca cgtactttgg
    15961 gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta tctgttattg
    16021 tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc ttgtctttct
    16081 tcggtcttgg attaccgatt acagtgccaa gtttgggtcg tttgatttcg gattattcac
    16141 aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt gtcttggtat
    16201 ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca cgtacacata
    16261 gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg atattgtcgt
    16321 ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc ttgaactagt
    16381 cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg ttttgacaaa
    16441 gaccttcaca ggtatgctcg aagaaaatgg tcgcattgcc caaggtagta ttgactaccg
    16501 tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc gtggtgctaa
    16561 gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa caattggtag
    16621 tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag cgaaagaatt
    16681 ggccattgac tacatgaata aggttggcat tccagacgca gatagacgtt ttaatgaata
    16741 cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg cccttgcctg
    16801 ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa ctattcaagc
    16861 tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa caatctttat
    16921 tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta tgtatgcagg
    16981 agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc atccatatac
    17041 atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc tttactcaat
    17101 cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg ccttgcgttc
    17161 tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag tatcagagac
    17221 acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa aaccagctgt
    17281 gattgcaaat ctccatgata agatccgtga aaaaatggga tttgcccatc tggctgacta
    17341 ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt tccttcggtg
    17401 aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac aagggagaaa
    17461 ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt gctatcatcg
    17521 gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt aatggtaaga
    17581 aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc caagaccctg
    17641 ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt ctttacaatc
    17701 accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaagtatt atccgtgaag
    17761 taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc ggtcaacgtc
    17821 aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt gcagatgagc
    17881 caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc aaaaaattcc
    17941 aaaaagagct cggcttgacc tatctcttca tcgctcatga cttgtcggtt gttcgcttta
    18001 tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca gaaacagaag
    18061 aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagca gtaccaatcc
    18121 cagatccaat cttggaacgt aagaaggtct tgaaggttta cgacccaagt caacacgact
    18181 atgagactga taagccatct atggtagaaa tccgtccagg tcactatgtt tgggcgaacc
    18241 aagccgaatt ggcacgttat caaaaaggac taaactaata atggttttat aatttccatg
    18301 tcaattttta tgggaattat aaaacttttt ttgttggact gatttgaaaa actttgaaag
    18361 cttcctgaaa gaattttcga aaaattttaa aaaattttga aatattattg acaggtgatg
    18421 aaaaaggtgg taggatagga aggatcaaaa aagaaagcag aaaaagaaat gaataagaga
    18481 caagccgtaa ctatgaatca aaacttttac tttagctact ttagatagtg tttgtagaca
    18541 tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta tctatgtggc taagattttt
    18601 gattgtggtc catatagatg aatatctaaa tggactagct aagttgtaac ttgttaggtt
    18661 atttcaagta cccgtttaga tagtatctag gcggtttttt gttttatctt ttctgagaag
    18721 gagtttcatt atgaaagttg ttcgaaaatc actagccccc tcttggtagt ggggatcctc
    18781 ttgacttctc tgatcagttt gcatcagttg aaggcagata agaaaagaga tgtctttcgt
    18841 atcggtattt cgcagtttat tacccaccag tccttagacg ctactagaga aggatttgtg
    18901 gatgagctgg ccaaacaagg ctatgttgag ggggaaaata ttgagattga tttgcaaaat
    18961 gcacagggag aacaaagaaa tctaaaaacg atttcccagc aactagcaga atccagcgat
    19021 gtcgttctag ccatcgcaag gccttctgct cagagcttgg ccaatacgac gcaaacgcca
    19081 ccagttatct tttcagctgt aacagaccca gtcagtgcca agttggttga gtcaagagaa
    19141 catcctgggg gcaatgtaac tgggacaagc gatcagtcat cagatgccat ttcaacccaa
    19201 atcaatttga taaagaaagt gttgccaaag gctaaaacga ttggaatcct ctatactcag
    19261 agcgagccca attcggttgt ttaaaatgat gaagctaagc gacttctgaa agaaaaaggc
    19321 tttaccgttg ttgaaaaaac aatcttggac agtaataacg tcaaggcggc agcagagagt
    19381 ttgatggcag aggtggatat ggtttttgtc ccaactgata atatcatttc gtcaaccatg
    19441 gaaacagtta agcaggtttc tattaaacac aaggttccag tattcggtgg ttcaacagaa
    19501 atgattgctg ttggtgactt gtataactac ggaaccaatt atgaagaatt gggaagacag
    19561 acagctcgca tgctgattcg tgttttaaaa ggtgagaaac cagaaaatat agcagttgag
    19621 ttgcctgaaa aactggaatt gcataccaat caagaaatgg cagatgcatt gggaattgat
    19681 attagtaagt tagaaggcaa ggaataagga ggattaagat gaattttgtg ttatctagtt
    19741 tatcagaagg tttgttgtgg tcgattgtgg cgattggggt ctacttgact ttccgtattt
    19801 tggatattgc ggatataact gctgagggag cctttcctct gggggcagca gtcgttgtat
    19861 cacagataca ggcaggggca aatccttggc ttgcgacttt acttgctttg ctggcaggta
    19921 tggtagcagg tcttgtatca ggaatgctcc acaccaagat gaaaatccca gctctcttga
    19981 cagggattgt gaccttgaca gggctctatt caatcaatat taaaattatg ggcagtgtac
    20041 ccaatctttc cttgggagat tctgcaaccg tctttaaaca gttggcgagc ttgggtctga
    20101 caaatgaagg agctgttttc tcacttagtt tagtctgtct cttacttgtt tggtcttgac
    20161 ccttttgatg aaaacagaga ttggtttggt cttgcgttcg actggggata atatcccgat
    20221 aagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca tgatttcaaa
    20281 cggtttgatt gccctatgtg gttccttgtt tgcccaaaat gatggatttt cagatgtgac
    20341 ttctgggaca ggaaccattg ttgttggttt gagctcggaa gtcttgatac acgacttgac
    20401 cattggaggc cgcttattat ccatcggaat cggtgctatt gtttaccgtt tgattatttt
    20461 aaatatctat gaaattccaa atctagatca aaacttggta cgtctcttta atgcaatctt
    20521 gctcgctttg gttttatttg caccagaatt gcaaaagaga ttaaagattc gtggtctgaa
    20581 attgagaaat gaataggagg agaaagttat ggcaagtttg ttaacacttg aaaatattca
    20641 caagacattt gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat tagatttaga
    20701 ggttgaagag ggagatttta tctatgtgat tggtggaaat ggagcaggaa aatccacttt
    20761 gatgaatatc ttggctggca atctatcggt ggacgaaggg gaccttctac tggcagggaa
    20821 atccattaaa aatctgagtg tcagaaagag agccaaggat attgcccgtg tttttcaata
    20881 tcctaagatg ggaacagctt ctcgtttgac gattgaggag aatatggcta ttgccttgag
    20941 acgtgggcaa aagagagggc ttggttgggg tgtgaaggag aaggatagaa tccagttcca
    21001 agaggccttg aaggagttga atattggtct tgaaaaccgc ttaaaagtag atactcaata
    21061 tctctcagga ggacaaagac aggctttgac cctagtcatg gcagctctgg tgaaacccaa
    21121 acttttactt ttggatgaac atactgcggc acttgacccg aaaaccagtc aaatggtgat
    21181 ggacttgacg caaaagattg tggagcacca tcagtggacg actttgatga ttacccatga
    21241 tatgaatcat gcgattgagt acggcaatcg tctcattatg ctctatcaag gcaagatagt
    21301 ggtggatgtc aagggagaag agaaaaagca tctgacagtt gaagacctta tgcatctctt
    21361 ccagaaaaat agtggccaaa gtctggtcag tgatgaatta gttttgggat aaagaaaaag
    21421 gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta caaatctaaa
    21481 tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt ggagatagac
    21541 ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa tcttgtctcg
    21601 gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga gtttgaggcc
    21661 attttctata taagaataga tagactgctc agcaatttgg cgagtgagat ttggaattag
    21721 ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca cacgctggcg
    21781 gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg attttttatc
    21841 aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa gttctttaac
    21901 tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt ctttgacgac
    21961 ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga gagacagggc
    22021 ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct cgctaggaag
    22081 gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct taaataattg
    22141 ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa tgaacacctg
    22201 tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt ttataccaaa
    22261 caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa cttgctttga
    22321 caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc tgcttcaggc
    22381 aattggaggc aaagaaaatg tgactgccgt aactcactgt gcgacacgga tgcgctttgt
    22441 tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag ctgttaaagg
    22501 aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc ccatctttta
    22561 taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag ccaagtctgc
    22621 agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg agatttttac
    22681 tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta atgtcttgga
    22741 aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc agttttgggc
    22801 aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct taccagtagg
    22861 gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa ttgttctcgg
    22921 aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa cgccagcagc
    22981 tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc gtatcggtta
    23041 ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc ttgaaatctt
    23101 ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct tgtcattgat
    23161 tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa ttggacaagg
    23221 gctttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct tcggtgcaat
    23281 ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga ccaatgccat
    23341 tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga ttgctctttc
    23401 taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc atgatgagcg
    23461 tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta cagaaccagc
    23521 tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga ctggttcagc
    23581 ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg gtatcggtgg
    23641 tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag gaactatgct
    23701 agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg gtctctttac
    23761 aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag aagcagaatt
    23821 tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac taactggcca
    23881 agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca tggggcaagg
    23941 tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga cagtgacggt
    24001 tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg aattgctcat
    24061 ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc ttgtagtcca
    24121 aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg tcattaaggc
    24181 tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt atacagcgac
    24241 tattcccgga acttatccga caacgatcca agctggagca tctctcatgg tcgctacacg
    24301 aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaat
    24361 agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc attgagtata
    24421 attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag aaaaggagaa
    24481 acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat cttacaaaga
    24541 caccactgaa aacggtattg gggatttccg tgggattatc ggaaaaattc cctatctagc
    24601 caaactaggt gtggatatgg tctggctcaa tccattctat ccaagtcctc aacgggataa
    24661 tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata tggctgattt
    24721 tgaggaaatg gtgtgtatcg gtaaagagca caagattgac tttatgctgg acatggtact
    24781 taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg ataagtatta
    24841 tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt ttggtggttc
    24901 tgcatgggcg cctttcgggg atactgggaa atactatctt cacctatttg atgagaccca
    24961 ggctgacctt aactggcgca atcccaatgt ccgtaaggag cttttcaagg ttgttaattt
    25021 ctggcgcgac aagggtgtca aaggttttcg atttgatgtg atcaatttga ttggtaagga
    25081 cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag acaaacccat
    25141 cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg atagctttat
    25201 gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt cgtcgcctga
    25261 tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact ataaggatgg
    25321 acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt accatagttg
    25381 gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca atcacgatca
    25441 accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag gagccaccat
    25501 gctagcagcc agcattcacc tgtcacgtgg gacaccttat atctacatgg gtgaggaaat
    25561 cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg aatcgcttaa
    25621 tgcctatcag atgctcttag aagaaggaaa gagtcagcaa gaagccttcc agattattca
    25681 agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg aaaatgcagg
    25741 attttcaaca ggcactcctt ggttgaaagc tggtaaatcc tataaataca tcaatgtaga
    25801 aaatgaaatc cagggtccga tttttacctt ctatcaagac ttgattcgac tgcgtaagga
    25861 aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca aacaagtcta
    25921 cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact tttatgctaa
    25981 agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga tttcaaacta
    26041 tgaagatgca gaagtgtctg agaaaattct actaaaaccc tatcaaacac tggctattta
    26101 tgtaaattaa acttagcaag gagacctctt tttcagaaaa gcaggtcttt ttttgctgtc
    26161 tattccatcc ttgaaagtgt agaacaaact ggtcagggtg gctagtttgt ggtataatga
    26221 aagggactca aaaagaaaca ggagaaaaat gatggattta cttttagcaa ttgtattgat
    26281 tgtgctagct tttctaggag gagctcttgg aggaatgtac ttggttcgta agcaaatcga
    26341 aaaagaattt gctgacaacc cacgtttgaa tgctgaagca gttcgtactc ttttgagtgc
    26401 aaatggtcaa aaaccaagcg aagctaaggt acaacaagtt taccaccaaa tcatccgcca
    26461 acaaaaggca gcccttgcta acaataaaaa gaaaaaataa ataaggaaaa gtctgggatg
    26521 aaagttccag acttctcact atgttggtta tggtttaggg atgagacttt ttccttgcat
    26581 tctattgata tttgattatg attaagagag aggtagttga cattctatca agctgtcggt
    26641 cagttcgttc agtacaagga atcataatga acgatcaatc agaaaaaaga ctagaaagaa
    26701 gactgtatgg ataatcgacc aattggtttt ttggattcgg gtgtcggggg cttgaccgtt
    26761 gtgcgcgagc tcatgcgcca gcttccccat gaagaaatcg tctatattgg agattcggcg
    26821 cgggcgccct atggcccccg tcctgctgag caaattcgtg aatatacttg gcagctggtc
    26881 aactttctct tgaccaagga tgtcaaaatg attgtcattg cttgtaacac tgcgactgcg
    26941 gtcgtctggg aagaaatcaa ggctcaacta gatattcctg tcttgggtgt aattttgcca
    27001 ggagcttcgg cagccatcaa gtccagtcaa ggtgggaaaa tcggagtgat tggaacgccc
    27061 atgacggtac aatcagacat ataccgtcag aaaatccatg atctggatcc cgacttacag
    27121 gtggagagct tggcctgtcc caagtttgct cccttggttg agtcaggtgc cctgtcaacc
    27181 agtgttacca agaaggtggt ctatgaaacc ctgcgtccct tggttggaaa ggtggatagc
    27241 ctgattttgg gctgtactca ttatccactc cttcgcccta ttatccaaaa tgtgatgggg
    27301 ccaaaggttc agctcatcga tagtggggca gagtgcgtac gggatatctc agtcttactc
    27361 aattattttg aaatcaatcg tggtcgcgat gctggaccac tccatcaccg tttttacaca
    27421 acagccagta gccaaagttt tgcacaaatt ggtgaagaat ggctggaaaa agagattcat
    27481 gtggagcatg tagaattatg acaaataaaa tttatgaata taaggatgac caggactggt
    27541 atgttgggtc ttatagtatt tttggtggcg ttaacagttt gagcgactat cagacagatt
    27601 ttcctctgtt tgaattctcc aaaatatttg gagatgaaga gtatggtttc ccgctttcag
    27661 ttactgtttt acgctatggt tctacctacc gtttgttctc ctttgtggta gatatgctta
    27721 atcaagaaat gggacgaaac ttggaagtta ttcaacgtca tggggccctg ctcttggttg
    27781 aaaatgggca actcttgtat gtagaattgc ctaaagaagg ggtcaatgtt catgatttct
    27841 ttgagacaag caaggtcaga gaaaccttgt tgattgcgac tcgtaacgaa ggcaaaacca
    27901 aggaattccg agctatcttt gataagttag gctacgatgt ggaaaatctt aatgactacc
    27961 ctgacctgcc tgaagtagca gaaacaggta tgacctttga agaaaatgcc cgccttaagg
    28021 cagaaaccat ttctcaatta acgggtaaga tggttttggc agatgattct ggtctcaaag
    28081 tcgatgtcct tggtggctta ccaggcgtct ggtcagctcg tttcgcaggt gtgggagcaa
    28141 ctgaccgtga aaataatgcc aaactcttgc acgaattggc catggtcttt gaactcaagg
    28201 accgctcggc tcagttccac acaaccctag tcgtagccag cccaaataag gaaagtttag
    28261 ttgttgaagc agactggtca ggttatatta actttgaacc taagggtgaa aatggctttg
    28321 gctatgatcc cctcttcctt gtaggagaga caggtgagtc atcagctgaa ttaaccctgg
    28381 aagaaaaaaa tagtcaatct caccgtgcct tagccgttaa gaaacttttg gaggtatttc
    28441 catcatggca aagcaaacca tcattgtaat gagcgattcc catggcgata gcttgattgt
    28501 ggaagaagtc cgtgatcgct atgtgggcaa agtcgatgcc gtttttcata acggcgattc
    28561 tgaactacgt ccggattctc cactttggga gggcatccgc gttgttaaag ggaacatgga
    28621 cttctacgcc ggctacccag aacgtctggt gactgagctt ggttcgacca agattatcca
    28681 aactcatggt cacttgtttg acatcaattt caactttcaa aagttggact actgggctca
    28741 ggaggaagag gccgctatct gcctctatgg tcacttgcat gtgccaagtg cttggatgga
    28801 aggcaagatc ctctttctaa atccaggttc tatcagccaa ccacgaggta ccatcagaga
    28861 atgtctctat gctcgtgtgg agattgatga tagttacttc aaagtggact ttttgacacg
    28921 agatcacgag gtgtatccag gtttgtccaa ggagtttagc cgatgattgc caaggagttt
    28981 gagactttct tgttggggca ggaggaaact tttttgaccc ctgctaaaaa tctagctgtg
    29041 ttgattgata cccacaatgc ggatcatgcg accctcttgc ttagtcagat gacctatacc
    29101 cgtgttcccg ttgtgacaga tgaaaaacag tttgttggga cgattggact cagagatatt
    29161 atggcttatc agatggagca tgacttgagc caagaaatca tggcggatac ggatatcgtt
    29221 catatgacaa aaacggacgt agcggttgtt tcgcctgatt tcaccattac ggaggtcttg
    29281 cacaagctag tagatgagtc cttcttaccg gttgtggata cagagggtat tttccaaggg
    29341 attattacgc gcaagtccat cctcaaggcc gttaatgccc tcttgcatga ttttagtaag
    29401 gaatatgaga ttcgatgcca atgagagaca gaatttcagc ctttttagag gaaaagcagg
    29461 gcttgtctgt caattccaag cagtcctata agtatgattt ggagcaattt ttagacatgg
    29521 taggtgagcg gatttctgag accagtctca agatttacca agcccagcta gccaatctaa
    29581 aaatcagcgc ccagaagcga aagatttcgg cctgtaacca atttctatac tttctctatc
    29641 aaaaaggaga ggtggacagc ttttaccgct tggaattagc caaacaagct gaaaagaaga
    29701 cggaaaagcc agagattcta tacctagact ctttttggca ggaaagcgac catccagagg
    29761 gccgcttgct agcgctctta atcctagaaa tggggctctt gcccagtgag attttagcca
    29821 tcaaggttgc ggacatcaat ctggattttc aggtgctgcg aatcagcaag gcttcccaac
    29881 agaggattgt caccattccc acggccttgc tttcagaatt ggaacccttg atggggcaga
    29941 cctatctttt tgaaagagga gggaaaccct attctcgtca gtgggccttt cgtcagttag
    30001 aatcttttgt caaggagaaa ggttttccat ccttatcagc tcaagtctta cgtgaacagt
    30061 ttattctaag acaaatagaa aacaaggtcg atttgtacga aattgcaaaa aaattaggat
    30121 taaaaacagt cctgacctta gaaaaatata gataatggat attaaattaa aagattttga
    30181 aggacccctg gacttactct tgcatctggt ttctaagtac cagatggata tctacgatgt
    30241 gcccattacg gaagtcatcg aacagtatct agcctatgtc tcaaccctgc aggccatgcg
    30301 tctggaagtg acgggtgagt acatggtcat ggctagtcag ctcatgctga ttaagagtcg
    30361 taaactcctt ccgaaggtag cagaagtgac agacttgggg gatgacctgg agcaggacct
    30421 cctctctcaa atcgaagaat atcgcaagtt caagctcttg ggtgagcact tggaagccaa
    30481 gcaccaagaa cgggcccagt attattccaa agcgccgaca gagttgattt acgaagatgc
    30541 ggagcttgtg catgacaaga cgaccattga cctctttttg gctttttcaa atatcctagc
    30601 caagaaaaaa gaggagtttg cacaaaatca cacgacgatc ttgcgggatg agtataagat
    30661 tgaggacatg atgattatcg tgaaagagtc cttgattgga cgagatcaat tgcgcttgca
    30721 ggatttgttc aaggaagccc agaatgtcca agaggtcatc accctctttt tggcaaccct
    30781 agagttaatc aaaacccagg agctgatcct cgtgcaagag gagagttttg gagatatcta
    30841 tctcatggaa aagaaggaag aaagtcaagt gcctcaaagc tagacttgat agagaggaaa
    30901 gatgagtact ttagcaaaaa tagaagcgct cttgtttgta gcgggtgaag atgggattcg
    30961 ggtccgccag ttagctgaac tcctctctct accaccgaca ggcatccagc aaagtttagg
    31021 aaaattagcc cagaagtatg aaaaggaccc agattccagt ttggctttga ttgagacaag
    31081 tggtgcttat agattggtga ccaagcctca atttgcagag attttgaagg aatactctaa
    31141 ggcgcctatc aaccagagct tgtctcgggc tgcccttgag accttgtcca ttattgccta
    31201 caaacagccg attacgcgga tagaaattga tgccatccgt ggagttaact cgagtggagc
    31261 cttggcaaag ttgcaggctt ttgacctgat aaaggaagac gggaaaaagg aagtattggg
    31321 gcgccccaac ctctatgtga ctacggatta tttcctagat tacatgggga taaaccattt
    31381 agaagaatta ccagtgattg atgagcttga gattcaagcc caagaaagcc aattatttgg
    31441 tgaaaggata gaagaagatg agaatcaata agtatattgc ccacgcaggt gtggccagta
    31501 ggagaaaagc agaagagctg attaagcaag gcttggtgac ggttaacggc caagtggtgc
    31561 gtgaactagc aaccactatc aagtcaggcg acaaggtcga agttgaaggt caacctatct
    31621 acaacgaaga aaaggtctac tatctgctta acaaaccacg cggtgtgatt tccagtgtga
    31681 cagatgataa gggtcgcaag acggttgtcg acctcttgcc caatgtcaaa gagcgtattt
    31741 accctgtggg tcgtttggac tgggatacat caggagtctt gattttgacc aatgatgggg
    31801 actttacaga cgagatgatt caccctcgta atgagattga caaggtttat gtcgcgcgtg
    31861 ttaaaggtgt ggccaataag gacaatctcc gccccttgac ccgtggtctt gagattgatg
    31921 gtaagaaaac caagccagct gtttatgaaa ttctcaaagt ggacccagtc aaaaatcgct
    31981 ctgtggtgca gttgatcatc catgaagggc gtaaccatca ggttaaaaag atgtttgaag
    32041 ctgttggtct ccaagtagat aagttgtctc ggactcgttt tggacaccta gacttgacag
    32101 gactccgtcc aggagaatcc cgtcgtctta ataaaaaaga aatcagccaa ctacacacca
    32161 tggctgtaac taagaaataa tgaaacgaat tttaatagcg cctgtgcgct tttaccaacg
    32221 ttttatctca ccagtctttc caccctcttg tcgctttgag ctgacttgtt ccaactacat
    32281 gattcaggct attgaaaaac atggttttaa gggggtattg atgggcttgt ctcggatttt
    32341 acgttgtcat ccctggtcga aaacaggtaa ggaccccgtt ccagaccgct tttcccttaa
    32401 acgaaatcaa gaaggggaat gaggtggggt aaatagattt caaaatgata aaaacgcatc
    32461 ctatcaggtt tgagtgaact tgataggatg cgttttagaa tgtcaaaatt ttatactctt
    32521 cgaaaatctc ttcaaaccgc gtcagctttc atctgcaacc tcaaaacagt gttttgagca
    32581 acctgcggct agttttctag tttgctcttt gattttcatt gagtattaaa ttgagtttga
    32641 agtggcttat ttcaaagctt tttgtatgtc ttcaatcatg agttttgttg attcaagtcc
    32701 gcctccgctt agataccaga ggtctggtgt tagttggata atcttaccat ttttagcagc
    32761 aggtgtttca gcgataaggg cattttctag gacaccgtcg ttgctagagt tgtccccacc
    32821 gatggcaagg gtacggttga tgacaaagag gatgtcaggg ttgatttctt tgacactttc
    32881 aaagctgact tcttgtccgt ggcgtgagtc ttcaaatgtt gtatcagttg gtttgaattt
    32941 caaggtttgg tacaagaaag agaaacgaga tttggcacca aaggctgcca tttttccttc
    33001 attaaggagg atcgcaaggg cttttttgtc agagctttca tttttagtag cgacttcttg
    33061 gatgctcttg tctagcttgg ccaattcttc cttggctttc tgtgtaccag tttcgccgaa
    33121 ggcacttgct aaggattcga tattagcctt ggtagaagtc cagtagtcgt ccttgcttgc
    33181 ttggaagaga acggttgggg cgatttcttt gaatttgtct acgaattttt gtgtacgtgg
    33241 tgaagcgata atcaaatcag gctcaagggc ggcgatagct tctaaatcag gttctttcat
    33301 agaaccaaca tttttgacag ttcccactag gtcttttaga taagtcggaa cagtttttgt
    33361 aggcattccg acgatatttt tttcaaatcc taaagcgcga atagtatccg cagcgccgag
    33421 gtcaaaggtc acaatctttt caggaacttt ggaaagtttg acctcgtcca gtgaactttt
    33481 aatggttacc tctgttggag cagagctact ggtctctgtc tgactagtgc ttgagtttgt
    33541 actacatgca ccaagtagga gcaagaagct ggccactagg gcagtgaaat aaagtttaag
    33601 ggatgttttc ataatttctc ctttttaaaa tgtgataacg atttagggag tctcttaatc
    33661 ttattgacta agagactgaa ggttctctaa cttgagcttt tatgttacta gctatagata
    33721 cagatctttt tgttattgat atcagctagc gtgatgggaa tctcataaag ttgactgagc
    33781 aggtcagcct gcatgatttg atcggttctt cccttgctaa agacctggcc gtccttgaag
    33841 gcgacaattt catctgcata ctgactggcc atgttgatat cgtggaggac gatgataatg
    33901 gtcttgccga gttcctccac cagtcgtcga agaatctgca tcatgctgac gctttgcttg
    33961 atatcgagat tgttgagtgg ttcgtccagc aagataaagt ccgtatcctg ggccagtacc
    34021 atagcgataa agacgcgctg gagttgcccc cctgacaggc tattgatgta gcggtctttt
    34081 aagttggtca gttccaaata gttcagagtt tctcggattt tttcccagtc ttctgatcta
    34141 agtcgacctc ggctgtaggg aaaacgtcca aaactgacca gttcttcaac agtcaatttg
    34201 gcttggtaat tgattttctg ttttaggatg gttagttctt gggccagttc ttgcgaattc
    34261 cagctctcga tttcacgtcc tttgatactg agaactccct gatctttctt ggttagtctg
    34321 ctcatgatgg agaggagagt cgattttcca gcaccatttg gaccaataaa ggctgtcagt
    34381 ttttgaggac tgacttcaag cgaaatgcct tgcaaaatat cctgtttttg aatggatttg
    34441 tcaatgtttt ccagtttcac tgacgagccc tcctatatag taagataaag aataagaagc
    34501 cacccacact ctcaatgatc atactgatac gaatttccag tgcaaagact cgttcaatca
    34561 aggcttgccc caaggttaag ctaataaatc caaccagaat ggccactata aagagtaact
    34621 tgtgctgata gtctttgaca atcaggtagg tgaggttggc cagcataaag ccgaagaagg
    34681 ccataggtcc taccaaggca gtggccgttg aggtcaaaag cacgattccc cagaggagct
    34741 ctttctgttc tttttcaaca tcgagtccca atatctgagc cgtttctctt tgcaggtgca
    34801 agacatctag aacgactgct tttcgaaaga aaaagattgt caaagcgagg atgatcagag
    34861 aaccgatggc taggatggaa gtgttaagat gttgaaagga ggcaaaaaga ctattttgca
    34921 gtttatcgta ttcgtttgga tccattagga cttgaaggaa ggtgctgata tttcgaaaga
    34981 gacttctgag cgctagacag atcagcagga tgaagaccag gtcttgcttc atcagtgtct
    35041 tcaagtaacc ttgtaaggcg agaaagaaga gggactggac aagaagtaag actaggaatt
    35101 ctaagatagg ggatttgccc agttgaagaa acttgctttc aaaaaccagt agtagggttt
    35161 gtagtaggac gtagaaggat tcaattccca aaatactagg cgtcaggaag cgattttccg
    35221 tcagggtttg aaaactaatg gtcgaaatcc cagtcgcgat ggctaccaag agataaacga
    35281 tgatcttttg ggaacgcaac ttccaagcaa aggctgacaa gtgagtgatg ggccaaaagt
    35341 agagaagaca agctccgatg gcaagaataa tgagaatcca gaagagcttg gtatgtttgc
    35401 ttttagtctg catcttttcg tccccctctc cagagaagta ggataaagac gagactaccg
    35461 atgattccta gcaagagact gacagacaac tcatagggcc taatcagaac tcgggatagg
    35521 atatcgcaag ccagaactag attggcacca accagtgcga ccatgagttt ggtttgactt
    35581 agattatctc catagcgctt gcgaacaaga ttgggaacga taactccgag aaatggtaag
    35641 ccacccacgg taatcatggt gacgcttgtc gttagcgcca ccagaaagag ggccagtttt
    35701 tcaagtaggg agtaggaaat ccccaaaccc tcgctggttt ctttccccag attcatgatg
    35761 gtgaaggttt gggataattt ccaaacggtt atcaggatga tgaggcctaa gaagagccac
    35821 tcatactgat gggtctgaat catggagaag gagccctggg tccaggcagt catactctga
    35881 accagattga aacgataggc gataacttct gtgactgagc cgataatccc gctatagatg
    35941 atcccaatca gaggcaacat ccacctttcc tttacagtaa aaatggtcat aaaggctagg
    36001 aagaagaggg tgaatacgat ggatgaaaca aaagcgaaga gcatcttttg ggtcagacta
    36061 gccgatggaa agacaaaaag gctcagcacc attcccagtt tggcggcttc agtcgttcca
    36121 actgtactcg gtgcagcaaa ctgattttgg gtaatagtct gcatgagaag gcctgccata
    36181 ctcatactag aggcagtcag gagaatactg atagttcttg ggagacggga ctcttgaaag
    36241 aggagccagg tctgctggtc gaaatcaaat agctttcccc atgaaaaatc actggtccca
    36301 atgctaatag agagaaagac taggagtaga agtaagccaa ttaaataatg agaaagtttc
    36361 ataccccgtc ctttcatgta gatttggtat cgaaagatat ctgcggatat aaatgtaaca
    36421 ttatttttct aatctgtcaa taaaatttct gacaatttaa taaatacaac aaggagagag
    36481 caacaagact ttctcctttg ttatcctatt ctaaaatgtt tttaccttaa tctgataaaa
    36541 taatatcttc gagggagtag ctagccgtcc aatcaagata ttgtttagct tttgaagcat
    36601 ctgctaggac actggctggg tcactagcac gtcgagcaac aatctcgtgt gggatttttt
    36661 aatttagtaa ttcttcagca gttttaaaga tttctttgat agtatagcct tttttagttc
    36721 ctaagttaaa gatttgagaa gaactgtctt cttgaaatag gtagttcatt cctttaacat
    36781 gagcctatgc aaggtccaag acataaatgt aatctcgaat acatgaaccg tcacgtgtat
    36841 cgtagtcatc tccaaatatt tttaagctat catgttgtcc caatgcggtc ttgttgatat
    36901 ttggaatgat gtgagttgga tttttcacac gcagaccgtt tgaagcatcc atttcagccc
    36961 cagcaacatt aaagtaacgg aaaataacat atttccagtc gtagcgattg gccatccagt
    37021 aaatcattcg ttcgcccatc agttttgtct ctgcataagg gttgacaggg tcgagcaggg
    37081 tatcttcagt caccggcttg tcaatacagt tatttccata gagagaagca gtcgaagaga
    37141 acatgatttt ttgaatgcca acttcagata agactttgag aacttggttc ataccagcaa
    37201 cgttggcagt gaagtattta cttggatttt caatactttc gctcacaaca atttcacctg
    37261 cacaatggag gacagcatca atctgatttt cttctaagta agcctttaag gcgctagcat
    37321 cataaacatc cagttcttta aagctagcac gactatccac agccgctcga tttcctgtgg
    37381 agagattatc gaggacatgc acctgatagc cagcatttaa aagagcttta acggtatggg
    37441 agccaatgta gctagtccca cctgtaacaa gaattgtttt ggtcatgatt ttttcctttt
    37501 ctagttttgt actatagtaa attgaaataa gatatgaaca actctattag gaaagtcgaa
    37561 ttaatttcta gaaatgtttc agcagctaca gcgtactatt ccaaactcaa ccaactatat
    37621 atttaaagaa agaagaaagg gaagtcaact attttctgta aatttcatga aaaatccaaa
    37681 caactttgat ggtgtattgt tttttttgtt tggaaataaa tattcgagtt aattttggaa
    37741 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    37801 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    37861 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    37921 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    37981 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    38041 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    38101 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    38161 aaccccatgg tagttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    38221 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    38281 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggatga ggcagaaagt
    38341 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    38401 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    38461 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    38521 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    38581 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    38641 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    38701 tttcttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    38761 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    38821 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    38881 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    38941 aaacattatt aaaccataag ggaggtggta gggatggcag aaccaaacct agaaagcctt
    39001 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    39061 ctagagactg ctaaaaaact gcctactaca aatgagcaat tgcaggcagt tcgtctctca
    39121 ggcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    39181 ttggctcgct ttatcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    39241 atgtatgagg aactctttaa aatgctttga ttccattgtg gatcaaagca ttttttgtaa
    39301 gatctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagcc
    39361 catagtagtg aagaaacttc tgtaatggaa gtggagcgaa gtgaggaatc gtcaaacggt
    39421 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    39481 aatgaaataa gatatgaaca aattgattga ggaaattaaa tgaatttata gaaatctttt
    39541 agcagtcatg gtgtcctatt ccagtttcga aatgctataa atacgaacaa attgattggg
    39601 aaattcaaat cgctttctat caatgtttta gaagatacag tgctctagtc taacttcaat
    39661 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatggt
    39721 ctgataggaa aaatgtgtcc cctcataaaa tataggatag tacgaatgga aggcttttgt
    39781 agactggagg acgaaggagt ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    39841 tggtgtggat aattatcaaa aattatttct aaatcgaaat agttgacagt tagaacgatg
    39901 agtgttacaa ttgttttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    39961 ggtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    40021 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    40081 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat
    40141 aatacgctaa cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    40201 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gtcccagaaa
    40261 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    40321 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcgaattt gaaagagaag
    40381 ggaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    40441 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    40501 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    40561 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    40621 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    40681 actttccgtg cggatgagaa tggtcgtatt gttgagcatt gggatgtcat tgactactat
    40741 cgaacacctg aaaatgatca actagatcaa atttttggag attttgaaat caaggatttg
    40801 gacaagaaag cagaaaataa aaaactggtt cgccgtttct tgacagaaat tttccaaaat
    40861 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgag
    40921 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    40981 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    41041 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    41101 cattgggata ataaggaagt catgcctaag gtagaagact tgactaatcg agggaagttt
    41161 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    41221 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    41281 cttctgggtc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    41341 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    41401 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    41461 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    41521 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    41581 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    41641 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    41701 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    41761 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    41821 gccaggtagc gaatcccgag acaattttaa aagtgcctgc aacagacttt gtagcagact
    41881 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    41941 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    42001 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    42061 ttgcagattg caggtatttt ccagaccatc ccgtctctgg ccttgttggg gctctttatc
    42121 cctttgatgg gaattgggac cttgccggct ttgacagctc tagtgattta tgcgattttt
    42181 ccgattttac aaaatactat tactgggctg aagggaattg atccgagtct tcaagaggct
    42241 gggattgcct ttgggatgac cagatgggag cgtctcaaga agtttgaaat tccacttgcc
    42301 atgcctgtta tcatgtctgg aattcggacg gcagcggtct tgattatcgg tacggctacc
    42361 ttggcgacct tgattggggc agggggactg ggttccttta tcctgttggg aattgaccgt
    42421 aataatgcca gtttgatttt gattggggcc ctttcttctg cagtgctagc tattgccttt
    42481 aacttcctac taaaagtaat ggaaaaagcg aaattgcgga cgattttctc tggttttgcc
    42541 ttggtggctt tattactggg tctgtcttat agtccagccc ttttggctca aaaagagaag
    42601 gaaaacttga ttattgctgg gaaaataggc ccagaaccag aaattttggc taatatgtat
    42661 aaattgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggacg
    42721 acaagtttcc tttatgaagc tctgaaaaaa ggtgatattg acatttatcc tgaatttacc
    42781 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga gccagagcag
    42841 gtttatcaag tggcgcgtga tggcattgcc aagcaggatc atctagccta tctcaaacct
    42901 atgtcttatc aaaataccta tgctgtagct gttccgaaaa agattgctca agaatatggc
    42961 ttgaagacca tttcggattt gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt
    43021 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctc
    43081 aatgtggcga ctatgcagcc agctcttcgt tatcaggcaa ttcagtcagg ggatattcaa
    43141 atcacggatg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    43201 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    43261 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    43321 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    43381 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagag
//
LOCUS       DAVBOU010000013        40621 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBOU010000013 DAVBOU010000000
VERSION     DAVBOU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40621
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.013"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..137)
                     /locus_tag="VQ879_000764"
     CDS             complement(<1..137)
                     /locus_tag="VQ879_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3142955.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     L"
     gene            complement(580..1035)
                     /locus_tag="VQ879_000765"
     CDS             complement(580..1035)
                     /locus_tag="VQ879_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142956.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1310..3047)
                     /locus_tag="VQ879_000766"
                     /pseudo
     CDS             complement(1310..3047)
                     /locus_tag="VQ879_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(3210..4094)
                     /locus_tag="VQ879_000767"
     CDS             complement(3210..4094)
                     /locus_tag="VQ879_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3142957.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(4206..5060)
                     /locus_tag="VQ879_000768"
     CDS             complement(4206..5060)
                     /locus_tag="VQ879_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3142958.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(5118..5876)
                     /locus_tag="VQ879_000769"
     CDS             complement(5118..5876)
                     /locus_tag="VQ879_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3142959.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(5938..6126)
                     /locus_tag="VQ879_000770"
     CDS             complement(5938..6126)
                     /locus_tag="VQ879_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3142960.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(6449..7015)
                     /locus_tag="VQ879_000771"
     CDS             complement(6449..7015)
                     /locus_tag="VQ879_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142961.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(7283..8962)
                     /locus_tag="VQ879_000772"
                     /pseudo
     CDS             complement(7283..8962)
                     /locus_tag="VQ879_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(9054..9215)
                     /locus_tag="VQ879_000773"
     CDS             complement(9054..9215)
                     /locus_tag="VQ879_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142962.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(9899..10213)
                     /locus_tag="VQ879_000774"
     CDS             complement(9899..10213)
                     /locus_tag="VQ879_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142963.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(10179..10568)
                     /locus_tag="VQ879_000775"
     CDS             complement(10179..10568)
                     /locus_tag="VQ879_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3142964.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(10956..11750)
                     /locus_tag="VQ879_000776"
     CDS             complement(10956..11750)
                     /locus_tag="VQ879_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3142965.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(11750..12757)
                     /locus_tag="VQ879_000777"
     CDS             complement(11750..12757)
                     /locus_tag="VQ879_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3142966.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(12757..13764)
                     /locus_tag="VQ879_000778"
     CDS             complement(12757..13764)
                     /locus_tag="VQ879_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3142967.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(13754..14779)
                     /locus_tag="VQ879_000779"
     CDS             complement(13754..14779)
                     /locus_tag="VQ879_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3142968.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(15172..15390)
                     /locus_tag="VQ879_000780"
     CDS             complement(15172..15390)
                     /locus_tag="VQ879_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3142969.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(15636..15914)
                     /locus_tag="VQ879_000781"
     CDS             complement(15636..15914)
                     /locus_tag="VQ879_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142970.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(16128..17759)
                     /gene="rlmD"
                     /locus_tag="VQ879_000782"
     CDS             complement(16128..17759)
                     /gene="rlmD"
                     /locus_tag="VQ879_000782"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3142971.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRGLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(17833..18807)
                     /locus_tag="VQ879_000783"
     CDS             complement(17833..18807)
                     /locus_tag="VQ879_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3142972.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(18881..19495)
                     /gene="pmp23"
                     /locus_tag="VQ879_000784"
     CDS             complement(18881..19495)
                     /gene="pmp23"
                     /locus_tag="VQ879_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3142973.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(19495..20469)
                     /locus_tag="VQ879_000785"
     CDS             complement(19495..20469)
                     /locus_tag="VQ879_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3142974.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(20477..21733)
                     /locus_tag="VQ879_000786"
     CDS             complement(20477..21733)
                     /locus_tag="VQ879_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3142975.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(21795..22226)
                     /locus_tag="VQ879_000787"
     CDS             complement(21795..22226)
                     /locus_tag="VQ879_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142976.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(22228..22827)
                     /locus_tag="VQ879_000788"
     CDS             complement(22228..22827)
                     /locus_tag="VQ879_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3142977.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(22814..23653)
                     /gene="prmC"
                     /locus_tag="VQ879_000789"
     CDS             complement(22814..23653)
                     /gene="prmC"
                     /locus_tag="VQ879_000789"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3142978.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(23653..24732)
                     /gene="prfA"
                     /locus_tag="VQ879_000790"
     CDS             complement(23653..24732)
                     /gene="prfA"
                     /locus_tag="VQ879_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3142979.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(24742..25221)
                     /locus_tag="VQ879_000791"
     CDS             complement(24742..25221)
                     /locus_tag="VQ879_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3142980.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(25211..25810)
                     /locus_tag="VQ879_000792"
     CDS             complement(25211..25810)
                     /locus_tag="VQ879_000792"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3142981.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            25933..26115
                     /locus_tag="VQ879_000793"
     CDS             25933..26115
                     /locus_tag="VQ879_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3142982.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            26252..27625
                     /gene="mnmE"
                     /locus_tag="VQ879_000794"
     CDS             26252..27625
                     /gene="mnmE"
                     /locus_tag="VQ879_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3142983.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(27672..28607)
                     /gene="dapA"
                     /locus_tag="VQ879_000795"
     CDS             complement(27672..28607)
                     /gene="dapA"
                     /locus_tag="VQ879_000795"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3142984.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(28663..29739)
                     /locus_tag="VQ879_000796"
     CDS             complement(28663..29739)
                     /locus_tag="VQ879_000796"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3142985.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(30081..30153)
                     /locus_tag="VQ879_000797"
     tRNA            complement(30081..30153)
                     /locus_tag="VQ879_000797"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30118..30120),aa:Thr,seq:ggt)
     gene            complement(30253..30762)
                     /locus_tag="VQ879_000798"
     CDS             complement(30253..30762)
                     /locus_tag="VQ879_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3142986.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(30760..30856)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            30885..31316
                     /locus_tag="VQ879_000799"
     CDS             30885..31316
                     /locus_tag="VQ879_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3142987.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            31398..31775
                     /gene="mscL"
                     /locus_tag="VQ879_000800"
     CDS             31398..31775
                     /gene="mscL"
                     /locus_tag="VQ879_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3142988.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(31817..32790)
                     /locus_tag="VQ879_000801"
                     /pseudo
     CDS             complement(31817..32790)
                     /locus_tag="VQ879_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
     gene            32945..34168
                     /gene="pepT"
                     /locus_tag="VQ879_000802"
     CDS             32945..34168
                     /gene="pepT"
                     /locus_tag="VQ879_000802"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3142989.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(34204..34833)
                     /locus_tag="VQ879_000803"
     CDS             complement(34204..34833)
                     /locus_tag="VQ879_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142990.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            34798..35019
                     /locus_tag="VQ879_000804"
     CDS             34798..35019
                     /locus_tag="VQ879_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3142991.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(35290..36301)
                     /locus_tag="VQ879_000805"
                     /pseudo
     CDS             complement(35290..36301)
                     /locus_tag="VQ879_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(36527..39646)
                     /gene="phtE"
                     /locus_tag="VQ879_000806"
     CDS             complement(36527..39646)
                     /gene="phtE"
                     /locus_tag="VQ879_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3142992.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(39857..>40621)
                     /gene="phtD"
                     /locus_tag="VQ879_000807"
     CDS             complement(39857..>40621)
                     /gene="phtD"
                     /locus_tag="VQ879_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3142993.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRVPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLY
                     KPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLT
                     GLKSSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
BASE COUNT        11889 a         8206 c         6727 g        13799 t
ORIGIN      
        1 attaattccg tagagactga actagttcca ttttcataac gactcaagct atttcgagaa
       61 attcctataa ttcgtgcaaa ttcaggttgt gttaagtcat gtgttttacg taaggatttt
      121 atgttctttc caatcatagt aaactccttt atttttataa ttcaattata gcataaaaaa
      181 gtataacgca ccaattttgg tgcgttatac tttttttcta gcctaaactt tacttctata
      241 aaagtcacct aaagagccat aaatatttat tcttgtatta attttttcga tgcgcaaacg
      301 atatctacaa atacatctat aacgattcac cttttaggat ttttattgtc aaaattgcct
      361 ttatctacaa agacaaaatg cttataaaat agcttgaaat caaggattat cacctttttc
      421 gttgtagcaa cactccacat gtgattatta ggctattagc aaagcgtatc caatacctca
      481 ataaagtgtt gtttttactg atattttaac tatattgtat agtctactat ttaaatctca
      541 attaggatat tttatagaat acccaaaatt caacaataac taaaagtaag attccattgt
      601 atttccttgt tggtctttca tatcacgaat tttatttttc agaatattaa agttacaaat
      661 ttcatctcta atatcgttat ccgctctgta gccattaatc atctcagtca gagttttccc
      721 tttactacca ttctttatag tagtatttac tctttttata ctgctttcaa aaggctcata
      781 tgttttatac ttaattactt cgtctttaaa attaaataaa ggtgtatccg gcttagcatt
      841 ccataaaata atcaaccaca ttatagcatt ataaagctgc tttgcagttt cattccactt
      901 ttcaggttgt aaatttccac tccctgtatt gtcatattct tgtctattat ttacatgaga
      961 atcacctaca agtggattaa aaagaggtag ccctttgtga ttaattagtt ctaaaaaatc
     1021 ccttgccgca cccatgcaac actgaataac ttccttcttg ccatcaattt tactctcagc
     1081 gataaataca taatattcat cttcaatagt tgctcctgca tcactatgtt tttgttgatt
     1141 tgctaacagc ttaatatgtg ctttaggcta aacttcaaaa tctctaacaa ttctttgtct
     1201 tgtttcatgt cctctacaat tcatttaagt tctcctttac aagtttagta actagcctta
     1261 ttatactata taagatatga aatgtaccat aatcttcatc aactagtttt tagaaaatca
     1321 caaatccatc tggagagatg acaagctgat tctccaattc ttggcaattg cttgctagtg
     1381 ctactgcttc tttctctaaa agataatctt ctgttgattg gttgaatatt gctttgagga
     1441 tccgtccttc gtatttccat tccagagcta ctaaatcaga tttgatttct tgaaggctat
     1501 acttgccatg cgaaataatt actgacgcgt atttccgaat cttaatcagc ctcttcataa
     1561 agttcagcat atcattgtca cttgatacac gttcccaagg catacaacga cgacaatctg
     1621 gatctggtcc tccagtcaag gctagctcgg ttccgtaata aatgcacggt gttccttttt
     1681 gtaaaaagag aaaggctaag gctgatttaa ccagttgaac atcttcattg gccgtccaca
     1741 ggattcgctc tgtatcatgt gaatccaaga gattaaacat gacctctgaa atctgctgct
     1801 tgtaatacat agactctcca ttgatttcat cgatgaactg gtctgtcttc ttaattcctc
     1861 gtaagaaata gtccttgata ctatcagata aaggataatt catgatggca tggaactcat
     1921 ctccatttag ccaaggctga gatgtatgcc agacttctcc taggatataa agatcaggat
     1981 ttttagctaa aactgcctta cgaaaatcct tccagaactg atggtcaatc tcattagcca
     2041 catccaaacg ccaagcatcg atattaaact cttcaatcca ataagtcgca acctttaaaa
     2101 gataattctt gacctctgga ttggctgtat ttagcttagg catatagtcc tcgaaaccaa
     2161 aaacatgata gggtaagtct ctcttattaa ctagtttttc agttgtcact gggaattgtt
     2221 gaatatggaa ccaatcctta taagcagact gttcaccatt tttgacgaca tttttccatt
     2281 gaagagattg cgaaccaata tgattaaata ccgcatccag catgactttc atgccacgat
     2341 gatgcgcttg atccaccagt tcccgaaagg tctccttgtc tccaaaatga cggtcaattt
     2401 caaagtaatc tgtcgtattg tacttgtgat tgcttgtaga ttcaaagatg ggacaaagat
     2461 atagtccagt aatacccaag tcttgcaagt aatccatatg atcaataatc ccctgtaaat
     2521 caccaccaaa gaaatcatcg ctcttaggtg tgacagatga atcccagtct aaagtccctt
     2581 ctgggtttaa tagagcattg ccattggcaa atctttcagg aaatatctga taccataccg
     2641 tatttgaaac ccagtcagga accttgcagg catcaatctt gaagataagg caacttaaat
     2701 ccattcccaa ttgcatgaag attttctaga gaattttcca cacacccttt atcgccatac
     2761 aaaatatttt gaccttctgt atctctgagc tcaaagagat actggatacg tgcaaagtca
     2821 actgacactt caacctgcca atggtcaaat aaggtaccag aagttatctt gaccatttct
     2881 tttgtatcct gataaaactc ctccataaag ataaaagggt ccccatagtg caagttgatg
     2941 ctttcaatgt cccctttctt agttcgaatt cgaatatgga gtttcttatc cttataaaga
     3001 taggcatact ccgactcagg cctatggtaa atagcactca attccatcaa tttgtctcct
     3061 aaagtattca ttcaaatttt acgcaaacgt tttcaaactc aatgaatcca gtatactatt
     3121 tttgtaaact atttgcaagg aatgtccgtt gttaaaggaa ctatctttta aagtatacaa
     3181 aaagccttaa aaaaggcttt ctctatatac taatcctctt tcggttttga aaatacttct
     3241 actcgctgag ctaggacttt gatttctaca ggtaggttat ctgatttatc tccgtcaaca
     3301 tctgactcca attcactatc tgaagagatt ttaatattac gcgctttgat atactcgata
     3361 ttatcatttg cgacaacatc cccttttaat aaatcaggaa tgacggataa tttggagaat
     3421 atagaggcat ctttcagaat caaaatgttg gcatagccgt ccttgttttc ttcaaagatt
     3481 ttcttatcag cgaagtaatt tgtcaaaagg accaaaacat ggctagcttc accaacataa
     3541 tttccatttt ctgtctcaac cttaatgtta aagacctgat ctgtcatgac agacttcatg
     3601 gtatttacag cataggttaa aataccgaat tttgttttgt cctctatttc aacattgtga
     3661 atcgcctcag gcagagaacc gatactaaag atataaccaa aatagttgtc atttgcttta
     3721 ccgatatcaa tcttattgat taaatcaaaa tccagttcgt caattgcgcc atcgatgtct
     3781 tgattgattt ccaaaagttt tgtaatgagg ttacccgtac cgcctgggat aatccctaac
     3841 ttaggaatgt agtctctctc atcaatacct gaaatgactt cattgacagt tccatctcca
     3901 ccaaacacaa ccactgcatc atactgctca cgagaagctt cttcagcaaa atgtgttgca
     3961 tccagcgctt tttcggtaat tttggtttca acatattcaa agtattcttt tgctttattc
     4021 tccagctttt ctttgtaatc caaagccttc tcgccaccag aagtagggtt gataattacc
     4081 attgcttttt tcattgattt tatccttaat tttaaacaga aatgtttaca tttcgtcgta
     4141 tgcaagtaaa tgtaatccta ttatacaatg aaaatacaga aaagagaaat ctgacatact
     4201 ggagattaat acgcttttat tctattttcc catcgcctaa ctacatcctt taagggttca
     4261 tccaagtaag aataggcctt atccttgatc caatcaggaa taccgtaagc tgcctctgct
     4321 atgctacaag tgattgctgc gagagtatca ctgtcgccac caagtgagat ggcatttctt
     4381 atcgcatctt cgaagtctct actttcaaga aaggcgataa tggcttgagg gacagtttcc
     4441 tgacatgttt cgttaaaacg atagttagga cggatttcat ctaaagtttg agatagattg
     4501 taatcgtatt ctttttctat ataatcctta attcgtcttt tacactctgt aggattgtcg
     4561 ttaattgatt gctcgtactc tctacaataa ccaccaaagt aaaaacgaca tagaaagata
     4621 gcatcagctg tagccatagc gcctttgaca ccttctggat gattatgagt tacctctgca
     4681 gaaagactcg taagtcctct agatgatggc cacataccag ttttcgcata aaaaccacag
     4741 tccatgatcc aagcacatgg agaaatacgc atagctgatc cattcccaaa gctattataa
     4801 ggctcacggt tatcgctgtt tagccatgca ttaaaccgag caccgtaatc agcattcgga
     4861 tacattctgc catatttctt catcgcgtca atgaaatcgt ctttttgtcc accattcata
     4921 attgcttctg caacagcaca ggtcataacc gtgtcatctg taaaaaagca gtccttccga
     4981 aataaaggaa agtcctttgt tttgatattg ttccattcgt aaacagaacc gacaatatct
     5041 ccaataattg ctccaagcat cagattcctc cttgttcatt ttgatgcttt ttatattggt
     5101 tatctaccat atttatttta gaaaataaca tcctgttgga ttttaaaaat ttcatttttt
     5161 tcaaaatagg gttttaccat ttctttccac ctagctctat gaaaattgat tgattttaaa
     5221 ggagataggc cataatttcc caatgcataa ccatcattta cttcaacaac aagtgttctg
     5281 ccatcgcgag taacaccgat atctagtcca taagctattg gcgcatcttt ccaacatgat
     5341 atcgcttcat caattacact tgcatcaaat tgtgcatgat aatcacctgt atagggtcga
     5401 acatctaata cgcgaccatc taacacaaaa caacgccatt cagctatgaa ttctacaacc
     5461 tcactaatcc atataggata gtcgaaaggt agaccaatac ctattaaatc atgggttcca
     5521 ttaacaactc ttccagtaaa gacttttgaa ccagctttag gcttaataaa ttttccccaa
     5581 ttatcaggta tattcacaat ctctcctaaa ataccagcat aaatctttcg accataaaac
     5641 tctttaagct caataggata gtcatgaacc ggaacgttta agcccatcat ttttagtaat
     5701 gctctagtct ccattatata atctacaact atatcttcac ttgttaactc ttttatttca
     5761 gaaaaagatt gatataaaat aacttcttct ccttgtaagt aggcacctac ttgagcattg
     5821 tatttattaa ttgaaacctc acttggtaat ttactttgtc taatataaac aaccatttca
     5881 tcactcctat atcactagtg ttacaccaat ttgtaaaaaa taatagcaat tttgctctta
     5941 tttttttgag taaatagccc ccataatatc atcgaaataa tcaacggtat ttaggagtaa
     6001 ttcaataacc tgggactttg ttagtcgcat tccccttcta tctctagcat cttctactaa
     6061 attttcaagt ttctctagat ttttatcatc caagctaatc attattctat ttttatcggt
     6121 tgccattttc atcacctcga gttaattcta tcacaggtgt aacacttgtg tcaactggct
     6181 tttataatac attagtttaa aagtggagag gatttttaac acagtaactt taaatctttg
     6241 gtattaaaaa attttcacaa tatttataga aataaaatct gtctcaaatc agttatcaaa
     6301 tctagtataa attatgagcg gctactctaa tactttccct ctaaacaaga aaaagactta
     6361 cactcaaggg ttttcttccc cccccttcgt tataacgttt tgactctttt actagcaaag
     6421 gtatatactc acaaggaact ttggttgact attgaatctc tccaacttct tctttaacat
     6481 atccttctac atcttcaatc tctacaaaca ttgggtctaa gtgacacaag aaatgccaaa
     6541 cttcgatccc tttttttctg taaagaatcg cttcaccgtc ttcacttccg aaaaagcttc
     6601 tgtcgatttc atatccgcgg ctttctaaga agtcttttgc tttacgatag ttcgtttctc
     6661 ttgtttcgac ataggcttta acttcatggt tgttaacgac atatgcatca atttttgaat
     6721 atccttcgat cactctatca tttttgaggg ataaatttga aatctctttc caaataatgt
     6781 ttacattttc ctcaggatcg aacataaatt tagataaagg aacaatattt ccgttaaaaa
     6841 taatttccat ataatccggt atgtttttag gattaaaata ctccacttca aaaccatctt
     6901 ctgtttccag agtgtatccc gggatttgag ctacaaaggc tttcccatct tctatggaat
     6961 caaatgctac taaatcttta gaataatcat tttggtacaa ttccaatata accatcgata
     7021 atctctccat tttcattatc aggctaatgt aaataagcac gtcacctgac caattcaggc
     7081 tctctgtatc atctcatcat atttcctact tactttacga gtcctatacc cagaacacac
     7141 cttatcgacc ttcggtctca cctcgtcgca ttggctgaac atctactttt acttcgctga
     7201 tgcttcaact cgtacaagca gtgataccgc ctcagcgtga tgcgtcagtg ggactcaaaa
     7261 agtttgggga accttttgag gattaactac gtttctctaa taaacttaca cattcaactt
     7321 gttcatcatt gtccaaatct atgttgagat tttcttctat aattggtagc ttaaaagtaa
     7381 tggattttag ccattgtccg ttagattgtt tttcttcata aacttgaatt tcagaaatca
     7441 aagctgaaat taactgccta cgctctacat cattcatgac tttatagagc ttatcaaaat
     7501 agatcagaac cttatatatg ttatctcctg taagcttttc agcttcaata gtctgtttct
     7561 ttgctttcgc atcaattagt gatgattcta attcatctat tttgtcatac atacgatata
     7621 gtctatcatc taaatcctgt ttccttctct tataatgctt atcttcaaca tctaaattat
     7681 ctatttcctc aattagctta aactttgtag aatgactctt tctcaattcc ttttggtaat
     7741 tatctatttc tttttctatt tcagaggtat ccaccttcat gttgattttt tcttgcatca
     7801 tagaagcaaa tttcggatta cttactatct tgacaatcac ctctgcaaca gcatcatcta
     7861 acaattcttc tctaatttgc ttactgaatg tacacttatg acctcttatc atctgcctat
     7921 ggttacaacc atagtaataa aaatctttat actttgtgcc atctttcttt ttcttgatac
     7981 acttgttccc aaacattccc actccacata tcgggcattt tacaattcca gaaagcaagt
     8041 gtgtgcgtgt atcttttcct ttattcacat gctcatattt ctttgcttga gattttagct
     8101 taacctgagc agcttaccaa acttcatcgg aaactatagc ttcatgtatc ccttcagata
     8161 ttagatattc atcttgttca acctgcttat attcatttct tgtaccatga actttttcta
     8221 aagttcttct tccaaatgct attttcccat tatatacagg attctttaat atctttctta
     8281 taagacctgc atcaaacaaa ggattcttac cattctgtct tgggattttt ctaattccat
     8341 gattctctaa gtatttagat atcccattgg ctcctatcgt agtatttaca tactggtcga
     8401 aaatcgttct tattgcaact gcctcttcct catttataaa cagcttgccg tcttcaagtt
     8461 tatatccata cggagcaaag ccaccattcc attttccttc ccttgctttt tgaatgcaac
     8521 cttccattgt ttgaatacgg atgttttctc tttctatttc agccacagct gataaaacag
     8581 aaatcattag tttcccagca tctttagatg aatcaatgcc atcttcaacg cagataagat
     8641 taactccata atcctgcatt atctgaagtg tagaaagaac atcagcggca tttcttgcaa
     8701 atcttgataa cttaaacaca agaacaaaag atactccatc ttttccagat tttatatctt
     8761 ccatcattcg attgaactgt attctacctt caatagactt gccagacttc ccggcatctt
     8821 catactctcc aacaatttca taatcgttgt aaatagcaaa agctttcatt cgtgattttt
     8881 gtgcctctaa cgaatacccc tctatctgta ttgacgtaga tactcgtgta tagaggtata
     8941 cttttatttt ttcttttgac atagtattaa cctcaatata atttttctat atcatatata
     9001 atttttttaa tttaagtttg gactatcatt tcaagtatat tataacactt ttattagtcc
     9061 gtctcaattt gtgtttttgc catgtcaaaa ctatttttca tctcttgatt ttttgctggc
     9121 gttggatcgg gtagattatc taaatctaaa gcaccagcat attttgcaat cagatttgct
     9181 attaaatcag ccaatccatt ccagtcattg tccaatatat acctcctcta aagttttata
     9241 tctaataatt atttgtttaa ttaagttttt tgacattgac aagtgctttg gattagcaac
     9301 ataggaatct cacctccgcc tctattccgg atgagccggc ttcaacctta gaagtatcat
     9361 tatcctcatt ttcttcatag cggatagggt atccctccct atattcaaac tcttacttat
     9421 cgctcacttt ctttttactt agcagaactt tttttgccga attattcagc cgaaagatct
     9481 tgacggatag gttattacgc tccaaaaata attaacgtct tgtcttggtc tattcaattg
     9541 ttaaggttca aaatttatcg agagttatta atctttttaa aatttgacca tcagaaaata
     9601 tttatcttaa tgtaacaaaa ttctataaat taccctctta tacttaacag tgaaaagaag
     9661 tctttcttgg taaccaattt tgaaatagaa tttgcttata taaaaaggtc aaattcccac
     9721 tgcataagta gcagtgaaaa ttagaccctc ttggtaactg tcatctaaaa gtcttctagc
     9781 atttctttaa ttttctaatc gcctttaaag tgtcatattt atattttttt atctctggca
     9841 tactttgata cctttttaga cttaaagtct ttaatagtgc ctttccacct ctttttatct
     9901 ataaagattc tcctacatca taattcattt ttttatttaa acctttctgt cttagtttgt
     9961 ctttatcttc ttcataccat tttaagattg tcacatagtg gttttgatag gtcttaccac
    10021 tgctttccat gtatctggat agtttattta tcattatatc tgtgtgtgag tttaattttt
    10081 cttttagatt tttatattct tctttgctta accttacatt tttgaattct ccataaaaaa
    10141 tgggggtgga ctttttatct atctctccct ctctctcttt atctatctct atatctttcc
    10201 atgtaattcc aatctggagt acctctactg tctatcggta atttaatttt gatatctggc
    10261 aatactgtgc tagatatttg atctttatat tcagtatttt ttaaagcttg cctaataatt
    10321 gaagttaaat agaatgctac ttctttattc aattctttat tttttaattt taaacaatga
    10381 attttcatat ctaggcttgc tttatattta tgataaaaga ctgctcctaa aaatgaaaca
    10441 gatataaaat tttcaaaaac tctataattt ttatcatcta tatcttcgta gtaacctaag
    10501 ataccattgt caatatttgt agcactaatt ctaggagttt ttccatcgag taaatatctt
    10561 tttggaatag atgagcctgt tggtacttga ctcgatttcc cctttttttc ggtaataaat
    10621 atttcttttt attttgttgt ccgatatttt tcctacctgt cctttgtagg atgagtattt
    10681 tctagatttt cttgaataac tttttacttg aagttttagc ttttgaacta gtcgttgtac
    10741 tttctttttg tttattatca gtcctgatct ttttaatatt gctgttattc tctatatcct
    10801 atttttcatt catgatattc ttttactaat tttatcttaa attctgtgct gtatttgcca
    10861 ttaaaaaact gacctccttt agttagtttt ttggcctaac ttttgagggt cagttcaaaa
    10921 tttgcgactt ttaaatgaat tccgatattc aattattaag agctaacatg gtgcttgcca
    10981 ataggaatca ttagaggcga attggaaata gggtcacgta taatttttgc ttcaagatta
    11041 aagatatctt taactagttt atcatttagt atatcttcag gctttccctc tgcaacaagt
    11101 ttaccttctt taattgcaaa taggtaatca gcgtatcttg ctgttagatt tatatcgtgc
    11161 aaaatcatgc aaatggttgt cttatatttt tggtttagat cagtcaagag gtctaatagt
    11221 tctatttgat atgagatatc caagtaagta gttggctcat ctaaaagtag gatacttgta
    11281 tcttgggcta gggctagagc tatccatact ctttgccttt gacccccaga aagttcttca
    11341 actaggttat ttgctagatc ttcaacattg gccttaacca ttgatctgtt tattatttca
    11401 aggtcatctt ttccaagact cttaaaaggc tttctgtagg ggaaacgacc acggcttaca
    11461 agatcagcta ctgttattga ttcagggatt attggagatt gaggtaatat agctatgtgt
    11521 tttgctaaat ctttttcttt ataagaatta attgatttat tatcgagcaa tacttctccc
    11581 tctaatggct ttataagtcg agacaaggtt ttaatgagtg ttgatttccc acaaccattt
    11641 gacccaataa taactgatat tttttcttca ggtattttta tatttatatt ttccaagatt
    11701 attttttcat cataaccgca ggtaagatta tttgaccaca gacctttcat tatatattcc
    11761 tcctgttcat ttttattagt aagtatatta agtatggtga acctaacaag ccagttacaa
    11821 cacctactgg atatctagct ggtaaaatat tttgagagaa tatgtctgat aacaaaacta
    11881 gtaaaattcc aaccaatcca gctaatattg ggcttctttt cttgccaata tttaaggcta
    11941 tgggaccagc taaaaaagat atacaagcta ttggtcctgt aattgaagta gaaaaagcag
    12001 ttaaagatac agcgcaaaaa attaaaacaa gccttgaaag ctcgggattt gctccaagtc
    12061 cgattgctat ttcttcacca agttcaataa tttctagtct tttattaaaa aataaaacta
    12121 atatagtagc aataatactt actattagaa caagaggtat gtcatctaac tttgtaaaag
    12181 ataaagagcc actgagccat ctcataactt cttgtaattc atatcttgct actttcaaca
    12241 ataaaaatga ggtgcctgct cttgtgacag cttgaaaacc aatgcctaat attatcagtc
    12301 ttgctgctga aaaaccatct tttttagcta gtaaaaataa tattaaagat gatgttagtc
    12361 cacaagttat tgaaataatt ccagtagtta aactatttgt ttttaatacc aatatgcaaa
    12421 agaccgctgc aatagatgaa gaacttgtga caccgattat atcaggactt gcaagaggat
    12481 ttcttaacat agtttgaaag ataaatcctg ccaatccaaa agaccagcca gctataattc
    12541 ctgctaataa ttttggtaat ctaatttcca taatcgaaaa actagctcca ggaacagttt
    12601 cactatttaa gactttaatc aaagttgaaa aagaataact ttcatctccg ataagtaaaa
    12661 tgaaaaatga tagactgatt attattaata aaaatagtga ggaaaatagt gttattctat
    12721 tttttctttt ttgaatacct ataattaaat tttgcattag ttattaaccc ctctattttt
    12781 catagttaca taaataagta ctggaccccc gattattgca gtaattatcc ctacttcaat
    12841 ttcacctggt ttacctaaca tacggccgat tatatcacat ataagcaaga gctctgcacc
    12901 tataaaagat gaagaaatgg tcattgtgcg tatatctttg cttataaata agccacaaaa
    12961 gtgaggaact ataagaccta cgaagccaat aggtccacca attgcagtaa tacttgaaca
    13021 taaaagcaca cttgcaatta ttgcaagtga tcttatccta ttaacattaa ctccaagacc
    13081 aacagccatt tcatcaccca tagctaaagc gtttaaatct gatgaaataa atatagctat
    13141 caaatgacct aaaattataa aaggtagtag tgtagatata gaagataatg tagctgctcc
    13201 aaggctacct atttgccaaa atctaaattt gtctaagacg ttattattcg gtaaaattaa
    13261 aaaacttaca aaactgctta aagccatact aacacaagtt cctgataagg caagttttat
    13321 aggggtaagg cctgcttttc cgcttacagc aatcgcgtat acaaaaattg cacttactaa
    13381 gccaccaatg attgcaaaac ttatatggct tatgcttgat gaaattccta aaaaagaaag
    13441 accaattact acactaagac ttgctcctgt gtttataccg agtatacctg gatcagctat
    13501 tgggtttcta gtaactgatt gcatcaatac accgcttatg gcaagactag aacctgctaa
    13561 aattgcaaaa atagttctag gtattctttt atatataatt gatttaataa aatcatcatt
    13621 tgtattaccc attccaaaag ctgctaaaaa atctctgata ttaatttctt ttgttccaag
    13681 ctttaatgac aaaaatattg taataagaag acctaggcag attacaaaaa ttatgcctag
    13741 gtttatttgt tttttatttc gcatttttgc atgcatttcc taaaagattt aggtattctt
    13801 caatagtata gtttattgaa agtggtgttg gagtgcatga ggctgctaac ggtgtattat
    13861 ctggaattac agcaacggca ccatttttaa ttgcatttat tttacctaaa agaggatctt
    13921 tttgtaaagc ttcaagagtt ttatcatcac cataagttat gattacatca gcatcattta
    13981 tcttatttgc ttcttctgca gaaatttcct ttgcaaaact atcttcactc tcaaattctt
    14041 ttaatgattc agggaaaact agacctaaat ctgttaaata atttgctctt ggatctttgc
    14101 tagtataaat ccagaatttt gatgtatctg cagcattaat catagtaaat aatacttttt
    14161 ttcctttgat ttttcctttg atttctggat gtttttctaa ttctttggat atacgagctt
    14221 cagtattttt gattaactca tcaccttctt tttccatacc taaggctttt gaatcaattt
    14281 taatcatatc tctccataaa gtttgccaag gtttagattt gtatgctgct acaggagcaa
    14341 tttttgatag agtgtcataa tcttctttag ttataccaga ataacctgct aagataacat
    14401 ctggtttaga atttgatatt gcttcaaagt taagtccatc caaatcgtca aataggttag
    14461 ctttaccatt tagttctttg attttttctt ctgtccatgg taaaactcct ttatcagcac
    14521 ttacaccgta atttgctttt gaaaatccaa caggaactat tcctaaagct aatgctacat
    14581 catgatttcc ccaagcaata gttgcaactc tttcaggttt tttatctaat atagtttgac
    14641 cgaaagcatg atctaaaact attttatcag gcgcatgctc tttagaagta ttttcttcat
    14701 ttttaacaga attagaagaa caagcgctaa aaactataca catagctaaa atagctatta
    14761 gaaaaaattt gtttttcata aaaactcctt aaacatattt caagtctatt gtatcgataa
    14821 taattatcat tgtcaataga tacagttaca aatttaataa tataattttt tcaaaaaagg
    14881 atctagtttt tatttttagt taaattatgt ctatattttt cattaactca tcaataaaaa
    14941 tttgtttgct aatatctctt tcttctgatt ttgtttcaag gattattgct acatcattca
    15001 tatttttagg taaataccaa ccatctggct tatctgaata tcccttgaag cctaattgat
    15061 taaaagtagt tatttgacca gtaccttgat tgatgttttc ttcaacttca ttaaagccta
    15121 tacttctctt gcataatccc taacttgatc ttctgtcctt aaagtcattt tctattcctc
    15181 gtcactaaaa ttatcttcaa aactaataat atcattagga gtgcaagata aagccttaca
    15241 tattctttct aaattcttaa atgtaattgg tttatccttt cccatttgtg ccataacatt
    15301 tgttgtaagt cctgccatag ctattacatc tgttttcttt agtccttttt ttgctaactg
    15361 tatccataat ggtttatagt taagtgccat aatatccctc tttttttctt cattagattt
    15421 atttaattat agcataaata ttgattttat tcaatcttac attgatttag tgatttgttt
    15481 tagagaattt gttgtgttat tccgtcctta ttttgccata aattgtttta agtgggacct
    15541 cttatcctta ccatttttac ctcctaattt tgagtataaa aaagacgata gagtttttaa
    15601 tttctatcgt ctgagattta catattaaat tttcatcaca aaataagact ctttaaagaa
    15661 tctttaaatt cattggtatg ctgcttacaa tatccattat taaaatggat attgtaagca
    15721 gcataccaac tatttatttt ttgagtttta aactttggta gaagtcttga actccttata
    15781 tttacataac tatttgcctc tataactgtt atgacacgaa accaacaagc aagttcaagc
    15841 acctccatat ctttattcaa atgaggacta agatattcac aaactttatc ataaacctct
    15901 ttatcttttt tcataaaagg ggcatacaac ttagcaaatt tatcctaaaa ttttttgttg
    15961 cctttatcaa tcatttcaac gctcctttaa atataaaaat gatcctatca atctttatat
    16021 tgagcctatt ttctaattga taccttgcaa gaaaggaata atagctgttc ctataccaag
    16081 taggaatgta ataaatgcag aaagtcatat actgtcattc ttttctatta aatcattttg
    16141 aagtgtctca aagcatccat gatggcttct tctttttcag gtgtacactg tggaataatt
    16201 tgtttatcct ttttagactt gttgtaatgt tctcgtaatt ctattccaca tttctttttt
    16261 atctgtgcaa tatataatgt cgaaactttt aattcaaatt tattccaaac atattctttg
    16321 atttgagcat atgttgcttt gctctccgca cttgtcaaat ccatctcatc cagctcaatt
    16381 tcaacactta tgtgcttatc gacatcaagt ttggacaaaa gtgctaccgt ctcgacgtga
    16441 tgcgtttgag gaaatagatc caccggctgg actttcttca attcatatcc caattcttgg
    16501 tagagtttga tatcacgcgc catggttgcg acattgcagg agatataggc gatgcgatcg
    16561 gctcctgttt gggcgcttgc tttgataaag ctttctgtca agcccttgcg tggaggatca
    16621 accaagataa cggttggttg aatcccatct ttaagccaat tcttcatagc attttcagct
    16681 gtgtcacaga catagtgggc gtttgaaata ttgttcagct gagcattttt tttactattc
    16741 tcaaccgctt ctggaatcag ttcaacaccg tagacttctt tgacatgctt ggcgactgat
    16801 aaaccaatgg ttccaatacc agaataagca tcaataacca cgtcatcttt ttttaactct
    16861 gcaaagtcaa tggctgtttg atagagtttc tccgccattt cagtattgac ttggtaaaag
    16921 gctgggccag cgatttggaa gtcatttccc aacatctggt ccgtaatata gtcttgacca
    16981 taaagagtgc gccactcctt accaaaaatc gcattggtat tctggtcgtt gatattttgc
    17041 atgacagaca caatctctgg gaactgcttg ataacttgtt caatcaattg gtcaacacga
    17101 aaaacttttg gacgagttgt caccaaaacg accatgattt gtcctgaata gtgaccacga
    17161 cgcaccacaa gattccgaat caatccagac tgttcctttt cgtcataagg ttttaaatca
    17221 aaacgacgga gcaggcctcg aagagctact acgacttggt caatgacagg atcctggata
    17281 aagaaatctt caaggggcat gaggtcgtgc gaattcttac ggaaaaatcc tgtttccaag
    17341 acaccattca ctcgacgaac gggcacctgc gccttattgc gatacttgac tggatgttcc
    17401 ataccaagcg tttcagcaac ttctacatct gcaattccag caatcttgta gagactgtcc
    17461 ttgacttgct tggttttaaa cttgagctgt tctggataag aaaggtgtcc taaatccgcg
    17521 attcctgaac gcaggtaagc caaatctaga tcttgattac ggtgtggtga ctggacaagg
    17581 tatttttcaa cttttccaaa gccaatcttt ttattgacct tgaggacacg catgagaatt
    17641 ttttcactcg gtaaagcatt ctctacaaaa aagaccaaac catctacctt ggcaactcct
    17701 gccccttcat gggtcaagtc aacaatttca acttctacaa tatcattttt ctttaacatt
    17761 cttttctctt tctattggcc gacaaaaaag acggtaacgt tacggttacc atccattata
    17821 ccatgaaatt tcttaagaac caaaactctt gaagaagttg acaagggctt gccagaggga
    17881 gcttaagaag ttaccaccgt cctctagcgc cttatccgca tcaaagttaa ggttgatatt
    17941 tttaaaactg tcgccagctt gtgatacgat gctttgttta aggtcattta gggttttagt
    18001 gaaatctgca ttgctgagga tatcactctt tgagagattc aaggcaaaat tgatgatgat
    18061 attgatctgg tttcctgtta tgacctgatc aagtttgtaa ttttttaagg tatcttcaac
    18121 aatcttgcgg atatcttctt ctgtcagatt tcccttgctt tctttagctt tggcgagtcc
    18181 tgacttgata tcagctaggg caacgtttaa tttattagca tcatagcctg atttgtcctt
    18241 gttttcagca ttgatatctg acaaagcttt tagctcttct tgagccaaat ctttattagc
    18301 ttgtggcacc ttggctccat tagcctctag cgaatagtaa atccctgcta aagcactttc
    18361 tcctgtaact ggaatagggg ctgctacagt gattttggca tgttccatac ccagcgttac
    18421 tgctgcgttt cggtacatat cctgagtcac cttagtgata ttttctggtg tttcaatctt
    18481 gacctcaagt ggcgatttgt cacctagctt ttgaatcttg gctgatgaat acaactgtaa
    18541 gctagagtca ttggccacat tcatgatttt agaataaaca tcaggtgtca tggtcttgag
    18601 ttctttggta tctgttgagg cattgtagcc cagtttttta agagtttgat ttttttggtc
    18661 ttcagatagg gaggaaccta ggacatattc aggttggaca taggtttcat cgataacttt
    18721 ttgaacatct gttgctgcat ggacgctatt catagctgtt actgcccaca agaccgcagc
    18781 actagtcaga aagagtttct ttctcatagg gaatttcctc ctttacttct ttatagtaat
    18841 atatctatct taaagaaaac ttataacaaa aacacctggt ctagccagat gttgaaaaga
    18901 gagtgaaaca tttgatgatg taaaggttaa gtcgtacctg tctagaataa taataatttc
    18961 ctccatttac atagagttca gcaccgtgaa aaatggaaat ggggtgaata taactataag
    19021 tctttccagt cgtattacca agcaaggggg caacagtctc acgagagtac tgtttggcta
    19081 gagccaaggt attttccttg ccattttggg cgataaaatc gatataggca ggtccaaaat
    19141 tataggcttg aacagctgtc cagatatcta cacccttctt ctgcgccaga tagagattgc
    19201 ctgtcagagt ttgaatgcct tgccgaatgc tagaggcatt atcattgatg gtgttggtgg
    19261 aaccacttgc agactcacta gactgcataa catcgccttc ttttcctttt gtttcagtat
    19321 aaatcatagc aagcacaagc tcttcgtttg ctggggtgtc tttttcactc aagatttctc
    19381 gcaccatggg ttgataggtc atgacttgtt tgacatcttg atgaacgcgg taagctttat
    19441 agccagcaaa aaggaagact gctagtacaa gcactcttcg aattcgttta aacattattt
    19501 actttggata tcctcgatat ttttgattaa gatagagtag gttccatttt cgttttggat
    19561 aaactcaaca gactcggcgt cttgatagac gttattggga acgatgagct caattccatt
    19621 tgataaggag agtttttggt tttcaaattt ctttaattgg cgacttgcat caatttcatc
    19681 aaattgaaca ggttctggta cggcttcttt gacttggtca ataaagctca aacgagccgt
    19741 cagattgttg tcaaaaaggt cattagccaa tttctcaggt gacaattcat tgctttcttc
    19801 taggttgttg aaaatcgctg atttgacctt ggattgaaat tgaaaatcat ctgtgttaaa
    19861 agattcagca attctctggg ctgttttttc cagttccttg atagattttt taggagaaat
    19921 cttaggagcg acagcaagaa gattatctga aaaatagttc aaaaaagtcc cgttgtactt
    19981 gattcgtttt tcaatcaggt gatacttgcg actctgaaga ttgaccacca aggcctcgtc
    20041 agcacccgtt ccaaatccag gcaggttatt ctgagtcagc ttgattggat tatcaacttc
    20101 tcctccgagg tgggtcaagg tctcccgcag ggcaattcgc aagaaagcga aatgttctac
    20161 accttcttta gaaaattgaa caaaaatcaa gtcattggtc ttgagatttt cagaaatgct
    20221 aaactcctct ttccagagat tagccagcgt tactgatgtc tccaacaaat cgtctgtaat
    20281 atgattgaag aagggatttt cttcttcgaa aatcccagtc ttggcttcat ctgaatacac
    20341 atgttcaatt tttttacgta ggtattcttc gatttttgga gtaatattga gaaacttatc
    20401 tgctaagaac agctcggtat catccggact gaactggtga ataatggctt tcttaatata
    20461 aatgtccata aaagttttat tcctcgtata atgggaaggc atctgtcaat tctttgactg
    20521 cacttctcac ttcttctaat acagcctcat tttctgaatt cttaagggtt ttaatgatga
    20581 gttcagccac tttgcgactt tcttcttcac caaatccacg tgcagtaata gctgctgctc
    20641 cgatacgaat cccacttgtc ttgaatggtg acaaggtttc gtaagggatt gaatttttat
    20701 ttagggtaat attgacttca tccagcaagt tttgagcaac ttttccgttt tctacaacct
    20761 tagtcacatc aacaaggaag agatggtttt cagttccacc tgaaataata cggaaatcag
    20821 ggtcttgcaa gaagacatct gccatagcct tgctgttctt aattacattg gcagcatatt
    20881 ccttgaaagc tggatccaaa acttctttga aggaaactgc cttagcagcc acaacatgct
    20941 ccaaaggacc accctgaata ccagggaaaa tagctgaatt gattttctta gctaaatcct
    21001 catcattggt caaaatcaaa ccaccacgag gaccacgaag ggttttgtgg gtcgttgttg
    21061 tagtgatatg agcgtatggc actgggcttg ggtgaagacc agctgcaacc aagccagcga
    21121 tgtgggccat atcaaccata agcttagccc caacagcatc tgcaatttca cggaattttg
    21181 aaaagtcaat aatttgagaa taggctgaag caccagctac aatcagtttt ggttttactt
    21241 cttgggcttg tttcaagata gcatcaaagt ccaaaagttc cgtttcagga tccacactat
    21301 aggaaagaaa gttgtaggtt tgaccagaga agctaactgg agctccgtgg gtcaagtgtc
    21361 cacctgctgc caaatccatt cccataaccg tatcacctgg ctcaatcaag gacatgtaag
    21421 ccgcacagtt agcttggctt cctgaatgtg gttggacatt ggcaaattta gcaccgaaaa
    21481 tttcttttgc gcgttcaata gcaagagtct ctacaacgtc tactacatca gttccaccat
    21541 aataacggcg tcctgggtaa ccctcggcat atttatttgt caagatagac ccttgagctg
    21601 ccataacagc cttggaaact acgttttccg aagcaattaa ctcgatatta ttttgttggc
    21661 gttcttcttc tttggcaata gcattccaga gatcagcatc atatgcttta aaatcatctt
    21721 tgtcaaaaat cataggtctt ctcctttatt gtgtgactag tccattagtt tgattttaca
    21781 ataagaaaat caaactaaaa gatgcgaata aaccgtttct gcattttatc acaagtatag
    21841 ccaacttttt cataaaatgc atgagcaccc agacgatgat tggcagaatt taagcggata
    21901 aacccataac cacatctttt ggcttcttgt tccaaccctt gtagtaaact tttaccgata
    21961 ccttgacctt gcgcttgagg tgaaactgct aaagctaaga tattaaatcc tgctttggaa
    22021 tagagtgatt cgtaaacttc agcgtggaca tatccaagta agacatgatt agctgcatcc
    22081 tcatagccaa gtaggaaatg atgggaatcc tgagacagtc tagctagttg gctagccgtt
    22141 tcctctggac taaaagtata acccaaagcc tcttggttga tgtcacatat cgctttcaca
    22201 tctgtttctt gcaaatctct tagcatttca agcctcctca aaagaaatct ctggcaaccg
    22261 agcaagaata tcttctcgtt taattgcgcc ttggcgtaag attttcacct tgtctccaga
    22321 caaatccaca atagttgaat cctgtccagt tagaaaagca tcgtcttcca gacccagaac
    22381 ctcttggtca aaatccttca gaatttgttc aaaggttaca ccacttgcct gacctgagat
    22441 attggcagac ggcccaatca agggacctgt ctctcgaatt aaatccagtg tgatagggtg
    22501 actgggcatc cgaaatccaa tagttgcaag gtcagaattt acccaatagg gaactcggtc
    22561 attggcttcg agaataatgg tcaagggacc tggcaaaaag gtctctacaa gtttttgtag
    22621 ataagctggc tgattcttag aaaagtgcaa gatatcctct aaagaggcaa cattgagatt
    22681 gagcgccttg tctctaggac gacgtttgag ctggtaaaca tggtcaactg ctttttcgtc
    22741 taaggccttg gcaaaaagac cataaaccgt ctctgtaggc agaatgacag ctccaccatt
    22801 ttccaactct tgtctaatcc tgtccatcat caaccacgac catcctatct tgaccaaatt
    22861 ggtccttgag tgttcgaact cttttttcag gaagatgttt cctaaaaagt tcgggaacac
    22921 tttgaccttg cttgtatcca atttcaaggt aaatcttacc accatccttg agatagtctt
    22981 ttgcatcttc cgcaattcta cagtaaatag ctaggccatc ctcgtctgca aagagagcta
    23041 gatgaggctc cgaatgcaaa acattcaagc ctacctctga ctcatcttca cgagagatat
    23101 agggtggatt ggatacaatt atatcatatt tttcagaaat ttctgcaaaa caatcagatt
    23161 ttttaaaaaa tatattaaga ttttgatcgc tagcattctc tgatgcaagc tctaaggcct
    23221 cttgagaaac atctgctgct gtcactgacc aatctggtct attttttgct agagcgagag
    23281 caatagctcc actacctgtt ccaatatcca gaactgagag attcgtctca agattttcag
    23341 ttagaataag ctccactaac tcctctgttt ctggacgagg aatcaaaacc cgttcatcca
    23401 cctttaaatg cattccataa aaatctgcct gtccaatgat gtactgagct ggcttgtgag
    23461 ctgctagttg ctggtaaata tcttctacaa attgtttttc ttcctctgtt gtcacctcct
    23521 gctggagggc aaaaataaag tctgtaaaag atagattttt cagactacga tagacaaaag
    23581 agaggctttc cgcttcctct ccttgtctta tcaactcttc ttcaaaattt gaaaataatt
    23641 gagctaattt cattatttgt ttaattcttc tagtttttgt gtttggtcat aaagcaccaa
    23701 ggcatccaca acttcgtcca atttaccaga caaaatcgta tctagttttt ggagggtcaa
    23761 gccgatacgg tggtctgtga cacggttttg tgggaagtta taagttcgga tccgttctga
    23821 acggtcacca gtaccgattg tcgacttacg ctcagcgtct tgttcatcct gagcaatctg
    23881 agcaaagtgg tcagcgacgc gtgcacggat aatcttcata gccttctcgc ggttcttctg
    23941 ctgggtacgt tcttcctgca tctcaacctt gatattggtt ggcaagtgaa cgatacgaac
    24001 ggcagtcgca accttattga cgttctgtcc accagcacca gaggcgtgat agatgtcgac
    24061 acgaaggtct tttggatcaa tgtcgtattc aacctcttca acttctggca taacaagaac
    24121 tgtcgctgtc gaagtatgaa cacggccttg gctttctgtc acaggaacac gttgcacacg
    24181 gtgggcacct gattcatact taagcttaga gtatacagac tgacctgaaa ccatagcaac
    24241 cacttcttta aaaccaccga caccattcat agaggcttcc atgacttcaa agcgccaacc
    24301 ttgggcttcc gcatactttt ggtacatagt tagcaaatct ccagcgaaaa gtgccgcttc
    24361 gtctccacca gctgctccac ggatttcaag gatgatattc ttgtcatcgt ttggatcctt
    24421 tggaaggagc aaaattttca gtttttcttc atattcttct ttttcagcct tggcatcttt
    24481 gagttcttgc ttggccattt cttccaagtc cgcatctccg cctgattcct taatcatctc
    24541 ttcggcatcg acgatatttt gaaggacttg tttatactca cggtaggcta ttacggtgtc
    24601 acgattggaa gcttcttctt ttgaaagctc cataaaacgc ttggtgtctg aaacgacatc
    24661 agggtcactc agcaattctc ctagttcttc ataacggtct tctacagctt gtagttgatc
    24721 atagatgttc attttttctc cttatttctc aattgttaaa tcatagattg ctactacttc
    24781 attctcggct atttccccag tttctttaaa tccataactg aggtaacaaa atcttgcctg
    24841 ttcattttct ggttcataag acaaccaaag tttattgctt aaacctgctg gcgctgttcg
    24901 aacatagtct agtactttat ccataattgg tttaaaatat ccttgatttt gaaaattcct
    24961 atcaatcata aaacgaaata gtaaataatt tccactacta attccgatct ttttatcata
    25021 agctatcatc acaaaaccta taattgcatc attatcataa actgccaatg tagctacaaa
    25081 atctccattt ttagtgtaga cgtatgcttc agctaaacta attgcgttgg ttgcaatgaa
    25141 ttgtttttga tattccttga catccaaatt taaaacatca aaataatttt ccattgtaac
    25201 atctcttagt tcaattgtca tagttttgct ccttgttaga ggttatcatt ggcgtaaaat
    25261 aatgtttacg gcaaactgag atataggttt cgttaccacc aatctggatc tgttctccat
    25321 cgtaaacggg cagtccatcc tgtgttcgca acaccatggt cgcctttttc ttgcaatact
    25381 gacagatggt cttgatttcg tcaatcttgt ctgctaaaag caagagatat ttggaacctt
    25441 cgaacaattc attgcgaaag tcatttttca agccaaaagc catgacgggt atgtctaact
    25501 cgtccacaac acgagctagg tcgtaaacat ggtggcgttt aagaaactgg gcttcatcga
    25561 ccaaaacaca gtaaggtttt tctggtaggt ctcggatata gccaaagata tccgttgttt
    25621 cctcaatcgc aagggcaggg cgtttcatgc caattcgact cgacacatag ccaacaccgt
    25681 cacgcgtatc cagagccgag gtcataatga caacaccttt tccttgctcc tcgtagttat
    25741 aggccacttt gagaatctca atcgttttac cagagttcat ggtcccataa cgatagtaca
    25801 actgtgccat gtttcttgct tcacgtccat ttctaaattt ttgctacatt ctagtatatc
    25861 ataattttct taagctttaa acggcaaaat gtggtaaaat ggaagaaatc aaaactagtg
    25921 gaggaagcta ttatgccatt tgtacgcatc gatttatttg aaggacgcac gctcgagcaa
    25981 aagaaagctc ttgctaagga agtaacggaa gcagttgtcc gcaacactgg agcccctcaa
    26041 tctgctgtcc atgtcatcat caacgacatg ccagaaggaa cttacttccc acaaggggaa
    26101 atgcgtacta aataagctag cttaagcaga attgcttagg ctttttcaat ctccaagtag
    26161 cattcattga agaaatatcc taaatttgtt acaatttgaa aagaaacttg gagaatttcc
    26221 aagaaaagag ctattaatta aaggaaacat tatgattaca cgtgaatttg ataccatcgc
    26281 tgctatctct actccactag gtgaaggggc tattggtatt gtccgcctga gcggaacaga
    26341 cagttttgct attgcgcaaa agatttttaa aggaaaagac ttgaacaagg ttgccagcca
    26401 cactctcaac tacggtcaca ttattgatcc tctgactggt aaagtcatgg acgaggttat
    26461 ggttggggct atgaagtctc caaagacctt cactcgtgag gatattatcg agattaacac
    26521 ccacggtggg attgcggtga ccaatgaaat tctccagcta gctattcgtg aaggggctcg
    26581 gttggcagaa cctggtgaat ttaccaaacg tgctttttta aacggtcgcg tagacttgac
    26641 acaggcagag gctgtgatgg atatcatccg tgccaagact gacaaggcca tgaacattgc
    26701 ggtcaaacaa ttagacggct ccctttctga cctcattaac aatacccgtc aagaaatcct
    26761 caatacactt gcccaagttg aggtcaatat cgactatcct gaatatgatg atgttgagga
    26821 agctactact gccgttgtcc gtgagaagac tatggagttt gagcaattgc taaccaatct
    26881 tcttagaaca gcccgtcgcg gcaaaatcct tcgtgaagga atttcaacag ctatcatcgg
    26941 acgtcccaac gttgggaaat ccagccttct caacaacctc ttgcgtgagg acaaggctat
    27001 cgtaacagat atcgctggga caacacgaga tgtcatcgaa gagtacgtca acatcaatgg
    27061 tgtacctctc aaattgattg atacagccgg tattcgtgaa acagatgaca tagtggaaca
    27121 aatcggtgtt gagcgttcga aaaaagccct caaggaagcc gacttggttc tactagtgct
    27181 aaatgccagt gaaccactga ctgcgcaaga cagacaactt cttgaaatta gccaagatac
    27241 caatcgcatt attctactta ataaaaccga cctgccagaa acgattgaaa cttcgaaact
    27301 acctgaagac gttatccgta tttcagtcct taaaaaccaa aacatcgaca agattgaaga
    27361 gcgaatcaac aacctcttct ttgaaaatgc tggcttggtc gagcaagatg ctacttactt
    27421 gtcaaacgcc cgtcacattt ccctgattga aaaagcagtt gaaagcctac aagccgttaa
    27481 tcaaggtctt gagctgggga tgccagttga tttgcttcaa gttgacttga ctcgtacttg
    27541 ggaaatcctc ggagaaatca ctggggatgc tgctccagat gaactcatca cccaactctt
    27601 tagccaattc tgtttaggaa aataagaaaa atccatgatc cttcattcgg tcatggattt
    27661 tattgtcttt attagtaatc tggtcttaag acccctgtta cagttgcctt agttgcttcg
    27721 tagtcgccat ctacgacaac cttgataatg cgtttggcat cttcttctgg tgctggaaca
    27781 agaggtagac gagtgggtcc agcttcaaat cccatatagt taagaattgc cttaactgga
    27841 gcaggacttg gataagagaa gagagcatta accttaggaa tgaatttacg ctgaattgct
    27901 gcggctttct tcatatcgct ttctgcaatg gcagtaaaca tctcgtgcat ttcatcccca
    27961 tttgtatgag aggcaacaga aataacccca tccgccccaa ggttcatggc atggaaagca
    28021 tctccatcct cacctgtata aatcaagaac tcttcaggct tgtgctcaat caagtaagcc
    28081 atattagcca agctagtaca ttctttgaca ccgataatat ttggatggtc agccaagcga
    28141 agcatggttt ctggagtcaa ttcgacaact acacgccctg gaatgttata gataataatt
    28201 ggtaggtcag aagcatctgc aatagtctta aagtgctgat acatcccttc ttgagaaggt
    28261 ttgttgtagt aaggaacaat agcaagccca gctgcgaaac caccaaattc cgctacttct
    28321 ttgacaaact caatagagtc acgcgtatca ttagtaccta cacccgcaat caaaggaacg
    28381 cgtccattga caaccttttg tacagccgca aacaactcca actcctcatc gtgggtcaaa
    28441 gttggactct cagcagtcgt tcctgcgaga agaattccat ccgtatgatg ggccaataaa
    28501 tgctcaatca aggctggaat agcatcaaag ttaatggaac catcctcatg gaagggggta
    28561 ataaaggctg taatgatttt acattctttt aaatcttgat aagacacgaa aacacctctc
    28621 tatttcaaag aaggagttca tctgaactcc taaacgatat gactatttta attcaaattt
    28681 caattcggct gttggacgaa ccaatccacg ttcatgaaga gtttcagcaa tctgaactga
    28741 gttccaagca gcacctttga gaaggttatc tgaaacaacc cacatgtgaa ttcctttttc
    28801 tgcatccaag tctttacgga tacgaccaac aaaggtatca cgcgaaccaa ctgcattgat
    28861 agcttgagga tagatttgat gagctacatc atcttcaaga acagcacctg ggaaggctgc
    28921 gatagctgct tttacttctt cgattggagc cacttctttt gtttcgatat aaacagactc
    28981 agagtgagct gacaagactg gaatacgcac acatgttgca gatactgcaa tgctatcatc
    29041 ttccataatt ttcttagttt ccttggtcat cttcatctct tcgtacgtgt aatcattatc
    29101 agtgaaaaca tcaatttgtg gaagagcgtt aaaggcgata ggataatgtt tcttgtcacc
    29161 acctgaaggc aagatttccg catgcaaatc acgtggtttc acaccatcat tcaaaacctc
    29221 acgaagttca cgttgtgtct caagaattgc tcccatacca gcacctgaaa cggcttgata
    29281 agttgaaaca atgatacggt ccaagcccca tttttggcga accggctcaa gagccaccat
    29341 catttggatt gttgaacaat tagggcaggc aatgattccg ttgtgagcat caagtgcatg
    29401 agcattgacc tctggaacaa ccaaaggaac atctggattt tgacggaaat aagatgtatt
    29461 atctactact accacgccag cttttactgc gtatggtgca tacttagctg atgtagaact
    29521 acctgctgaa aagagagcaa tatcaactcc ttcaaaagct gtttcagtcg tttcttcaat
    29581 tgtaatatct tgatctttaa atttcaatga cttacctgct gaacgtgcag aagcaaggta
    29641 acgaatttta tcgattggaa gtgttgattc ttccaacatt tttatcatct gagcaccgac
    29701 agcacctgtc gcgccgacta cagcaactgt atatcccata aataacctct ttcggaattt
    29761 tctaaaaatt tctataatag aagtattata ctactttttc catgaattgc aaagcttttt
    29821 catcattttt tggaaaataa aaatcccagt cgctagacta gggactaaga ggcatcttca
    29881 tgtgatgagc aggttcacac aactcatcaa ggtccgctcc tgcgttatga cctccttatg
    29941 ctcaatagta gtccgaagac tacctatcga ctcatcgcat attctatatt actagagata
    30001 cttgattttg tcaataagaa attttttcga tcgagtataa caaaaaactc tcgtattcaa
    30061 gagtttccct atacatatca tgctaattgc cgggattgaa ccggcgacct catccttacc
    30121 atggatgcgc tctgccaact gagctaaatc agcttactta agaagtatac tatattcaga
    30181 aaaacttgtc aagtttcctt agaaattttc cataggaaaa agccaggtaa gaactaccta
    30241 gcttatcttc ttctatttac ttaaatcaat tcgacgacca attttaccaa taataatcgc
    30301 cccaataatc aatgaagcaa attcaccgat tcctgttgta aaccaagtaa ggaagaatgg
    30361 taattctgct acaatattta actctgcagc gatagtaaac atggaaattg aaaagaggat
    30421 tgaaaagaag aaatgatctt ttcgaatcaa tccgttaaag aggtaatcct tgctatattt
    30481 tgcaaaaagc caaacaccta aactgaggaa tactaaggtt gaaccaccac caacaaagac
    30541 atctagcagt ccgaagctaa agaaattagc aatcatacaa ccgatggtaa ctccgatgat
    30601 gtacttagga ttgtaaaaag ccataaagtt catcatttct gaaatacgaa actgataagc
    30661 accatagctg atggcattta ggggcggtgt gacagtcaaa acgacgtaga tagcagcgac
    30721 gattgcaata tctgcaacat cacgaatagt taattttttc atcttttctc ctttggcggt
    30781 tgcccgcgtg taatatgctt ggtgaaagaa gctaagcacc aagggttgct ttattcaacc
    30841 ctactagtat agcacaatag cctgctttat gctatactta acacatgaaa attcctattc
    30901 aaaaattttt taacaatgaa atcttagcct atctcttttt tggccttgcg acaactctag
    30961 tttcgattct ctcacgacta gtcatttatc aactaagtca tcaggaactc ctggctactg
    31021 ccctagcaaa tattatcggt atcctatttg cctttatcac aaatgatacg attgtattta
    31081 agcaaaaaaa gaaaaataga cttatccgtt tagtgaaatt ttctcttgct cgcctttcta
    31141 cttttctgtt agacttgttt ttaacttttc tctttgtaac ccaatttcct cacattatag
    31201 ggcaattcgt aactgaaaac attgataaga taaatgctat tgaaacaata attgcacaaa
    31261 tattcattat tatcatcaat tatatcttga gcaaggccta tatttttaga aaataatgct
    31321 ccatttatga gccttttaat tgccttctat aatgatttag gatacaatga aacacgaaac
    31381 attgaaagga aaacagtatg ttaaaaaatc taaaatcgtt cttgcttcga ggaaatgtta
    31441 ttgaccttgc tgtcggtgtt gtaattgcct ctgcttttgg tgctatcgtt acttcacttg
    31501 taaacgacat tatcactcct cttattttaa atcccgcttt gaaagctgct aaagttgaac
    31561 gtatcgctca actttcttgg catggagtcg gctatggtaa cttcttaagt gctattatca
    31621 attttatctt tgtgggtacc gccctcttct ttattatcaa gggcattgaa aaagcacaga
    31681 aactgactgg cataaagaaa gaaaaaactg ccgaaaaaaa accaaccgaa ttggaagtcc
    31741 ttcaagaaat aaaagctctc cttgagaaaa aataatcgat taaaaggatc tagcgcaaag
    31801 ctaaatcctt ttttctttac tctttgggta acttgcctgc tttttcaagc atttttttga
    31861 tcagataagg catcttaaca ttctcccgcc cttttttctc aatcagtttt ttcacaaatt
    31921 ctggcatttg taaatcttca gattcagcta aaatgttttt cgtctcgtct gaaggaacta
    31981 actcatcaaa ggtctcttct tctgggagaa attccttaaa ctcttgattt tcattgactc
    32041 taactgtatt gaccaaagca tcaatcaaac gagaatctgt atttggcatt ggtgaacgat
    32101 ggtagtttac cccaaattcc tggcataagt cataacattc tacatcattg tcaaacaaga
    32161 cctcaatatg ctcactgatg aaactaatag gtacaaaaat ataatggtct ggatgttctg
    32221 tctgttctct gagatactcc aaaacaaagg atcaccaaag tccaaggcaa aaatgggcac
    32281 actatgggct gaaaagatga ctttaaaact gtcttgcttt acttcttctt ttaaaatctt
    32341 agcaatttca tctgcccaat agtttaagag cacttcttcc tgataccagt ccttaatgac
    32401 caaaaattga atttgtttgc tttctaaaaa tttttcatag cccatgacag agtagaaaga
    32461 ataatggggc tccaaaatca agcaaataca ctgttcaatt ccgtctgctt ccatttgacc
    32521 gatcacatct ggaataaagg gactggaaaa cttattagca aagtagacac tgtattcatt
    32581 ccccagccta gcttctacca aggtaacctc ttgacgggta attttttgca gaggcgtgcc
    32641 tccaattcgt acataattat catagagagt ctgaatctcg tggtcttggg gtctcacccc
    32701 acgacgaata tttgtgaaaa aatcagctac accttcaaag gtaatctctt ctggtgaacc
    32761 gaaggtcatc attaaaattg cttttttcat gactgcttcc ttgtgatgtt tttatcaagt
    32821 ttattttatc attaattcat cgataagtaa acgctaacat agggacattc tcaatcttct
    32881 gtcttttgtt tttctcttct ttctatgata caatggaaaa aataaattca aaaggagttt
    32941 ttttatgact tatccaaatc tcttggaccg cttcttaacc tacgttaagg tcaacacgcg
    33001 ctctgatgaa cactctacta ctactccaag tacacagagt caggttgact tcgcaacaaa
    33061 tgtcctaatt cctgaaatga aacgtgttgg actgcaaaat gtttactatc taccgaatgg
    33121 ttttgctatt ggaaccttgc cagccaacga tccgtcttta acacgtaaga ttggttttat
    33181 atcgcacatg gatactgctg attttaatgc tgaaggagtc aatccacagg taattgaaaa
    33241 ctacgatggt ggtgtgattg aactagggaa ttctggtttc aaactcgatc cagctgactt
    33301 caagagtctt gaaaaatatc caggacaaac gctcatcaca acagatggaa caaccttgct
    33361 aggtgctgat gacaagtcag gaattgctga aattatgaca gccattgaat atctaactgc
    33421 tcatcctgaa attaagcact gtgagattcg tgttggtttt ggtccagatg aagaaatcgg
    33481 tgttggtgcc aataaatttg atgcagaaga ttttgatgtg gattttgcct acactgttga
    33541 tggtggtcca ctaggtgaac ttcagtacga gactttctca gccgctggtg ctgaattgca
    33601 tttccaaggc cgtaatgtcc accctggtac tgccaaaggg cagatggtca atgcccttca
    33661 gctagcaatt gattttcata atcaacttcc agaaaatgac cgacctgagt taactgaagg
    33721 ttaccaaggt ttttaccatc taatggatgt gacaggtagt gttgaggagg cgcgtgcaag
    33781 ctacatcatt cgtgattttg aaaaagatgc ctttgaagcg cgtaaagcat ccatgcaatc
    33841 tatcgctgat aagatgaatg cagaacttgg gagctaccgt gtcactctca acttgacaga
    33901 ccagtactac aatatgaaag aagtcattga aaaagatatg actccaatta ccattgctaa
    33961 agccgttatg gaagatctag gtatcacgcc tattatcgaa ccaatccggg gtggaacaga
    34021 cggctctaag atttccttta tgggaatccc aactccgaat atctttgcag gtggcgaaaa
    34081 tatgcacgga cgttttgaat acgttagcct tcagactatg gaacgtgcag ttgataccat
    34141 cattggcatc gtagcttata aaggctaaaa agacgaggta gctcagctac ttcgcctttc
    34201 tttttattct actggttttt cttgatttcc agtagttgta gaagattctg ttgtttcatt
    34261 ttctgaagtt gattcagcag gtttagaatc tcttgtattg cttggtttgt tttcgtcgct
    34321 agcaatttca atgttagatt ctgcagttgc gtttggttgg ttctcagcac tggtgttatc
    34381 actatttgct tcagcatttc ttgctggact tgtttcttca cttgcgctag cttttgactg
    34441 gatttgatga ttcaaaacta gaatagcttt tgtcgattca agtaaagctg ttttgtcttt
    34501 actcttagca gaaagttgat ctaataatgc atccacctta tcaaagtccg catcagatcc
    34561 attattactt tctaaataag agtgaagcga catgagaata tcgtagagtt tttgatagag
    34621 tacaagtgtc tgagaatctt gctcagcatt ttccttttct tgttgaaggg cgctagcgat
    34681 acgagtcaag acatctttta cctgactgtt tacttcatcc aagtctgcat cagccttgtt
    34741 tgtggcagct tttagatttt ctacttcttc tgccaaggat tgtctgattc cttcttcatg
    34801 gatttgttcc aagagttgat ttaccttgct caaaagactt tctacttctt ccttgctatc
    34861 tgtcgcagat tattggttgc catctaccat gtactcctaa aacaggagag ttataatcca
    34921 agattacaag gccttacaga aataagaaat ccagataaga caatgttcgt ccaagacgct
    34981 attcgcttcg cacagcagca cggattcaat atgctttaat tttaaagttt aggtgtcaag
    35041 acctcttttt agtgtgccca aaatttagag aagtaatcaa tcaactaact tttatttttt
    35101 tcaaactttc agtaaactga cctaaagcta actcaatctg tctttgtaga tgcttctgct
    35161 atcagctaga agttgatcta cttttgccaa gactgccttc tcatcaaaag ttccaggttg
    35221 atagttggat tgcagggatg gaatcttgtt tttcaaagcc gcttcatatc ccttagtttg
    35281 aaccttgatg tagtgattgt ggtcgccatg aggaatcaca aaaccttctg aatcttcact
    35341 tataattcga ttggcatcaa aaccatgacc atcttcttcc tcatgatgga catgtagtga
    35401 cggattactt aatacagaac tagaagaact tcctacctct tccgtgttag agtgtgatgg
    35461 gggattgtta agagatgact taggaatata gtgatagtga tccccatgtc ttactatata
    35521 agcatcacct gtatctctga caatatcatt agggttaaag acatatgtgg ctgctaattc
    35581 acctgccgac aagtcactct caggaatgaa atgatagtga ccaccatgtg gtactatagt
    35641 agattgaaat agaatatgag caaattgata aggggatttt aaagtaattt ctaacaatga
    35701 tttagaaact atgatgtgct attctaaatt caactcacta tatataacca tcatcggtag
    35761 tataacgtcc ctgtaatttt gctacagata cttctgcact agctccttta tcgtctttac
    35821 catgttcttg tttttggcga ttgatttcat cttttgttcg tacattttct gcatgagctt
    35881 gatctttaag gtaaacataa tactttccat ctaccttaat aatatatcct cccttaacct
    35941 aactgacgat atcttgatct ttcggctgat agttgggggc tttcattaat agctcttcac
    36001 taaagagcgc atcaaaagga actttaccat tatagtagtg ataatgatcg ccatgagaag
    36061 ttacataacc ttgatctgta atcttaataa caatttgttt tgcttgaatt ccttcttttt
    36121 gactaaccta gtctggagtc aaattttcag tcttcttagt gtctttatta ctgtttacat
    36181 atgaaacacg atttttatct gtattggcct gttagctatg ttggttcaga gcataaacac
    36241 acagacttaa ggaaaggata acaacagatc cagctgctat atatttcttt ttaaatttca
    36301 taattacctc atttctataa ttatttatat gatgtcttca ttattaaatg attaaataaa
    36361 ttaattaacc aattaattaa ctagtaaata ttccacctct ttttaagttg tatgtcaaga
    36421 aattttatat attaataata aaatgaaatt ctcccaaagt cagagtttta tttctaactt
    36481 ttgagagaac ttcatttttg attcagactt tttctactgc tattccttac gctatgagat
    36541 cagataaatt cttttttatc acttctccac ttggcaatct taattcaatc gttccatcca
    36601 tattgaatat aacactatct aagcctaatc cgtaactagc tgtaaatttt tctaattttt
    36661 cttgtacagg atctactgct ggagcttcct ctaatgctgg atctaacata gggtcactcc
    36721 ccacattccc ttctggattc aacattccat tatccgttga gttttctggt tttacaggtt
    36781 tttcgtttgg tgcctctggt aaagaatctg ctggtttatt ttctgttggt tggttctcaa
    36841 ctgttccagt agatactttt ccagtttcag atggtttatt ttcaccattt ccttgaggtg
    36901 cttctcctgt aaaatctgcc atattctttt taatgacttc tcccgatggt aaatataatt
    36961 caattgttcc gtccatatta aacaagacat tttctagctt catcccataa ctttcagcaa
    37021 attttgctac tttttcttgt acaggatcca ctgtaggaac ttcttctaac gttgaatcac
    37081 tagtactgtt cccagtttca ggaagctttt ctttttctac cttctcacta gtctttggtt
    37141 cttctacctt ttcatcaagt tttgagtttt cttgtgcttt attcctttta aattgtggta
    37201 gaatacttgg tttatcagtt tgattttctt tttccaagat aggtacttcc acaatataag
    37261 tcgattgatt gtccaaataa gcatttgcca tgaaggttac aggaatttta tttccggccg
    37321 ttctggttgt tccttggttt aatttcggaa tcggtaattt aatttcacca actttatagt
    37381 tattttctaa ataagcattt ccatgaaatt catcaaacac tctgactaaa gcatcagttc
    37441 ctttaggcac tgcaaattga gggttcactc ttaaataagt atcccctgca tggaaaggat
    37501 agaaaatcgt ttgactggcc attttgtaag ctaaagaggt tggaactgta aatgtaccat
    37561 cataacttac ttctggataa tcttttgaag cgatagtata cttaaatgtt tgtcctggta
    37621 aataaggttg atctaattca aagtttgcaa tattccctac tccttctcca aatactttac
    37681 cagatacttt ctccaatact tttccatctg gtgttattaa ttttactagc atattgatac
    37741 ctaatttttt ttccaattca ggcggaaaac taaaagaaac gcgtttttga ccattggcta
    37801 gagtaaagtt ttgattatta aacgtactat tttttaacaa attaacaaca ttcgttaatt
    37861 cttctccagt ataaacttta ttcccttctt ttttagcaac tccttcttcg ggtttaaaca
    37921 gttcatagtt actgtgagaa tgaccaattc caaccggttt atgttcatca atcggatctg
    37981 catgatggtg atctccatgc ggataaataa tcgcattttt ttctttattc acgacaatac
    38041 tttcacgttt gacaccatat tgtttcataa tgccagcaat tttttcttcg atttttttat
    38101 ctaaatcttt catttctttg gcattacctg gataatcctg ttcatgagat gacaaagaat
    38161 ctaatccatt atgactagtt ttaacttcct ctaaatgttt ttgcgcagcc ttaatttgct
    38221 cttctgtcaa gtccttcttg aagaaataat gattgtggtc tccgtgactc atgacaaaac
    38281 ctgattcatc ttcagcgata atacgattag catcaaatcc gtatccatct tcttcatgtt
    38341 tctcatgtga agttcctgga ttgattggaa gagatggaga aggtgttgct agactattgt
    38401 ttggaagagt cggttgccca atttgatttg attttggaat gtaatggaaa tgatcaccat
    38461 gtcttacaat ataagctgta gccgtttctt caacgatatc ttttggatta aaaatataac
    38521 catcagatgc tgaagagagt ttcttacttg tcgttaaaga agaaggattg cttgaaagac
    38581 tgcctagact agacactact tcattaggtt ttgcatttgt agaaactgta gaaccagttc
    38641 cactgatagg caccattctg gcaatctttt cttctaaggc agaaagcttg ctgtaaggaa
    38701 taaagtggta atggtcgcca tgcggaatcg caactccatt tggtgtacga ctgataatct
    38761 tagcagggtc aaagaccagg ccatctgatt cactgtaacg ttgggcgcta ggtgaatcat
    38821 agagttcctt caaaagactc tggagatttt cagatttatt tgctggcttg ctagttgatc
    38881 cttttgctac agattgcgtg ttattgtcac tagctgttga agaatagctt aactgactcg
    38941 gttgcatatt ttttccagcc agatgtgctt tagctgctgc taattcacta gcagataaat
    39001 cgcttttggg aatgtagtga tagtgacctc catgaggaac gatataagca ttacccgtat
    39061 cttcgataat atcagctgga ttaaagacat aaccatcatt tgtcgtatat cgtccctgag
    39121 accttgctac agcaacatta gagttaacct tctcattatc tttgacatgt tcttgttttt
    39181 gacgattgat ttcatcttta gttcgaacat tatcagcatg agctgcatct ttcaggtaga
    39241 cataatattt tccatcgacc ttgatgatat aaccaccctt gacttcattg acaatatcag
    39301 cgtctttaag ttgatagttt ggatccttca tcaagagttc ttcactaaag agggcatcat
    39361 aaggaacttt cccattatag taatgatagt ggtcaccgtg tgacgttaca tagccctgat
    39421 ctgtaatttt gattacaatt tgctcagcct gaattccttc tttctggcta acctggtctg
    39481 gtgtcaagtt ttcacttttc tgacttgact ggctgccatc cacataagag acacgattat
    39541 tgtccttatt ttcctgcgaa cgatgctggt ttagtgcata ggcacataga ctcaaggata
    39601 cgataacagc tgatccagct gctatatatt ttttactaaa tttcataaat ccctcatttc
    39661 aataaatgat gaagtttttt tctcaacttc ttttacttta ttaaatagtt ttctaaaccg
    39721 attatttaac catttaatta accagtaaat agtctactat ttaaaattac ttttgtcaag
    39781 tttctgttac gtttttctaa aaaagagaag taacacgaaa ggttacttct ccataaaata
    39841 tgctccattc attttactac tgtataggag ccggttgact ttcttttaac aaagccaaga
    39901 gactatctac ttctgctgaa atagtattat tatctttcgt tccgagaaga agactacttt
    39961 ttagaccagt caatgtctcc atagcatttt gtctaatact agaatctgtt actttttcta
    40021 gcaaggcctc cgcctctgct atcttagcgt taataacaga atgctctact tgaggaattt
    40081 cagcctcatc tgtagtatct tcagcttctt cctctgtctc ttccgtatca gtgcttggtt
    40141 tataaagatt atctgctgaa ggatttaaac cagcgtgatt ctctttttca tcagattcag
    40201 ggtgagttgg ctcacttact tcatcatgtt ccttatcttc ctcaggtttt tctgtctgag
    40261 gtttctccgt ttgattggta tcagcttgac catttttgtt tctttgaaca tggtcgctag
    40321 cgttaccaaa accattatct gaatgcggac gttcgtttgg atgttcgaca tagtacttga
    40381 cagtcgccaa aagatcctca agagtatacc ccttaggtgc ctcataaagg ccttcgtcaa
    40441 accactcaaa tttgatgtta tggtaatggt cataatgagg tatgattaaa ctaccgtttt
    40501 tgacttctac agtatattga agattgtaag gcacacgatc aagtggcacc ttcttagctg
    40561 ctttcacgcg gttgtagata gcttctgctc cttttgcctc agtatttcct gaatcctgat
    40621 g
//
LOCUS       DAVBOU010000014        40463 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBOU010000014 DAVBOU010000000
VERSION     DAVBOU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.014"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            5..75
                     /locus_tag="VQ879_000808"
     tRNA            5..75
                     /locus_tag="VQ879_000808"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37..39,aa:Gly,seq:tcc)
     gene            110..183
                     /locus_tag="VQ879_000809"
     tRNA            110..183
                     /locus_tag="VQ879_000809"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:144..146,aa:Ile,seq:gat)
     gene            266..355
                     /locus_tag="VQ879_000810"
     tRNA            266..355
                     /locus_tag="VQ879_000810"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:302..304,aa:Ser,seq:tga)
     gene            369..442
                     /locus_tag="VQ879_000811"
     tRNA            369..442
                     /locus_tag="VQ879_000811"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Met,seq:cat)
     gene            446..518
                     /locus_tag="VQ879_000812"
     tRNA            446..518
                     /locus_tag="VQ879_000812"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:479..481,aa:Phe,seq:gaa)
     gene            531..611
                     /locus_tag="VQ879_000813"
     tRNA            531..611
                     /locus_tag="VQ879_000813"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:565..567,aa:Tyr,seq:gta)
     gene            616..686
                     /locus_tag="VQ879_000814"
     tRNA            616..686
                     /locus_tag="VQ879_000814"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:648..650,aa:Trp,seq:cca)
     gene            701..773
                     /locus_tag="VQ879_000815"
     tRNA            701..773
                     /locus_tag="VQ879_000815"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:734..736,aa:His,seq:gtg)
     gene            787..858
                     /locus_tag="VQ879_000816"
     tRNA            787..858
                     /locus_tag="VQ879_000816"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:819..821,aa:Gln,seq:ttg)
     gene            868..951
                     /locus_tag="VQ879_000817"
     tRNA            868..951
                     /locus_tag="VQ879_000817"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:902..904,aa:Leu,seq:caa)
     gene            1058..2335
                     /locus_tag="VQ879_000818"
     CDS             1058..2335
                     /locus_tag="VQ879_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3142994.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2411..3895
                     /locus_tag="VQ879_000819"
     CDS             2411..3895
                     /locus_tag="VQ879_000819"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3142995.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVCYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3956..5236
                     /locus_tag="VQ879_000820"
     CDS             3956..5236
                     /locus_tag="VQ879_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3142996.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5240..5860
                     /locus_tag="VQ879_000821"
     CDS             5240..5860
                     /locus_tag="VQ879_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3142997.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6026..7204
                     /locus_tag="VQ879_000822"
     CDS             6026..7204
                     /locus_tag="VQ879_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3142998.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7717..8055
                     /locus_tag="VQ879_000823"
     CDS             7717..8055
                     /locus_tag="VQ879_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3142999.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8066..8434
                     /locus_tag="VQ879_000824"
     CDS             8066..8434
                     /locus_tag="VQ879_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3143000.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8541..9185
                     /gene="pcp"
                     /locus_tag="VQ879_000825"
     CDS             8541..9185
                     /gene="pcp"
                     /locus_tag="VQ879_000825"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3143001.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9213..10070)
                     /locus_tag="VQ879_000826"
     CDS             complement(9213..10070)
                     /locus_tag="VQ879_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3143002.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10200..11342
                     /gene="tgt"
                     /locus_tag="VQ879_000827"
     CDS             10200..11342
                     /gene="tgt"
                     /locus_tag="VQ879_000827"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3143003.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11443..13260
                     /locus_tag="VQ879_000828"
     CDS             11443..13260
                     /locus_tag="VQ879_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3143004.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13413..14564
                     /gene="nagA"
                     /locus_tag="VQ879_000829"
     CDS             13413..14564
                     /gene="nagA"
                     /locus_tag="VQ879_000829"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3143005.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14727..15785
                     /locus_tag="VQ879_000830"
     CDS             14727..15785
                     /locus_tag="VQ879_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3143006.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15936..16301
                     /locus_tag="VQ879_000831"
     CDS             15936..16301
                     /locus_tag="VQ879_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3143007.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16377..17318
                     /locus_tag="VQ879_000832"
     CDS             16377..17318
                     /locus_tag="VQ879_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3143008.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17266..18282
                     /locus_tag="VQ879_000833"
     CDS             17266..18282
                     /locus_tag="VQ879_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3143009.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18284..18610
                     /gene="comGC"
                     /locus_tag="VQ879_000834"
     CDS             18284..18610
                     /gene="comGC"
                     /locus_tag="VQ879_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3143010.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18603..19007
                     /locus_tag="VQ879_000835"
     CDS             18603..19007
                     /locus_tag="VQ879_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3143011.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19012..19272
                     /locus_tag="VQ879_000836"
     CDS             19012..19272
                     /locus_tag="VQ879_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143012.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19235..19696
                     /locus_tag="VQ879_000837"
     CDS             19235..19696
                     /locus_tag="VQ879_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3143013.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19674..20087
                     /locus_tag="VQ879_000838"
     CDS             19674..20087
                     /locus_tag="VQ879_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3143014.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20224..20818
                     /locus_tag="VQ879_000839"
                     /pseudo
     CDS             20224..20818
                     /locus_tag="VQ879_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20879..21832
                     /locus_tag="VQ879_000840"
     CDS             20879..21832
                     /locus_tag="VQ879_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3143015.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21883..23073
                     /locus_tag="VQ879_000841"
     CDS             21883..23073
                     /locus_tag="VQ879_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3143016.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23222..23593
                     /gene="rnpA"
                     /locus_tag="VQ879_000842"
     CDS             23222..23593
                     /gene="rnpA"
                     /locus_tag="VQ879_000842"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3143017.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23568..24392
                     /locus_tag="VQ879_000843"
     CDS             23568..24392
                     /locus_tag="VQ879_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3143018.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24411..25397
                     /locus_tag="VQ879_000844"
     CDS             24411..25397
                     /locus_tag="VQ879_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3143019.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25448..26071
                     /locus_tag="VQ879_000845"
     CDS             25448..26071
                     /locus_tag="VQ879_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3143020.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26202..27659
                     /locus_tag="VQ879_000846"
     CDS             26202..27659
                     /locus_tag="VQ879_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3143021.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27682..27963
                     /locus_tag="VQ879_000847"
     CDS             27682..27963
                     /locus_tag="VQ879_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3143022.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28040..28525
                     /locus_tag="VQ879_000848"
     CDS             28040..28525
                     /locus_tag="VQ879_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3143023.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28542..29207
                     /locus_tag="VQ879_000849"
     CDS             28542..29207
                     /locus_tag="VQ879_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3143024.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29211..30074
                     /locus_tag="VQ879_000850"
     CDS             29211..30074
                     /locus_tag="VQ879_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3143025.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30076..30780
                     /locus_tag="VQ879_000851"
     CDS             30076..30780
                     /locus_tag="VQ879_000851"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3143026.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30959..32632
                     /locus_tag="VQ879_000852"
     CDS             30959..32632
                     /locus_tag="VQ879_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3143027.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32744..33835
                     /gene="ulaG"
                     /locus_tag="VQ879_000853"
     CDS             32744..33835
                     /gene="ulaG"
                     /locus_tag="VQ879_000853"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3143028.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33949..35925
                     /gene="tkt"
                     /locus_tag="VQ879_000854"
     CDS             33949..35925
                     /gene="tkt"
                     /locus_tag="VQ879_000854"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3143029.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36042..36341
                     /gene="yajC"
                     /locus_tag="VQ879_000855"
     CDS             36042..36341
                     /gene="yajC"
                     /locus_tag="VQ879_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3143030.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36387..36815
                     /locus_tag="VQ879_000856"
     CDS             36387..36815
                     /locus_tag="VQ879_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3143031.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36817..37227
                     /locus_tag="VQ879_000857"
     CDS             36817..37227
                     /locus_tag="VQ879_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143032.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37526..40177
                     /gene="adhE"
                     /locus_tag="VQ879_000858"
                     /gene_synonym="adhC"
     CDS             37526..40177
                     /gene="adhE"
                     /locus_tag="VQ879_000858"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3143033.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12275 a         7248 c         9108 g        11832 t
ORIGIN      
        1 tttagcgggt gtagtttagt ggtaaaacta cagccttcca agctgttgtc gcgagttcga
       61 ttctcgtcac ccgctttgaa ctttgttctt tgtaccaagt ttttgacttg ggcgcgtagc
      121 tcaggtggtt agagcgcacg cctgataagc gtgaggtcgg tggttcgagt ccactcgtgc
      181 ccatagtgtt tagtccatta ctaggggatt ggaatattat ctgttcacta agaggacacg
      241 ggcttgttcc cgtataaact attttggagg attacccaag tccggctgaa gggaacggtc
      301 ttgaaaaccg tcaggcgtgt aaaagcgtgc gtgggttcga atcccacatc ctccttttat
      361 attattaacg cgggatggag cagctcggta gctcgtcggg ctcataaccc gaaggtcgta
      421 ggttcaaatc ctgctcccgc aataaggctc ggtagctcag ttggtagagc aatggattga
      481 agctccatgt gtcggcggtt cgattccgtc tcgcgccatt tatatatttt ggaagggtag
      541 cgaagaggct aaacgcggcg gactgtaaat ccgctccttc gggttcgggg gttcgaatcc
      601 ctccccttcc attttacggg catagtttaa aggtagaact aaggtctcca aaaccttcag
      661 tgtgggttca attcctactg cccgtgttaa tagaattatg gcgggtgtgg tgaagtggtt
      721 aacacaccag attgtggctc tggcatgcgt gggttcgatc cccatcactc gcctatttta
      781 tattattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
      841 cgaatccagc taccccagtt actatttgcc ggcgtggcgg aattggcaga cgcgctggac
      901 tcaaaatcca gtgtccgcaa ggacgtgccg gttcgacccc ggccgccggt atagtatagt
      961 gttaggaacg ttgttattct tcgttccttt tttatattat ttttggtata attatagtta
     1021 ttcaaatttt atttagatta agaaagtgta gggtagtatg tcttgttcta tcgatttatt
     1081 aaaacatcgg tatttgaaaa atattaaaga aaatcctgaa ttgtttgtcg gaattgagtt
     1141 ggagtatcct gttgcaagtt tagaagggga tgctacagat gttgaagtta taaaggatct
     1201 atttcattat ttagtttcta ctttggatct caccgtagca aaggtagatg attttggcaa
     1261 tctgatccag ttagtagatc cgataagtca ggatgctatt ttatttgaag tttcctatac
     1321 aacgattgag tttgcatttg gtaaggctga aacgattcaa gaggtcgaaa atcgtttcaa
     1381 taattatatg aatgtaattc agagaaagtt agctgaatca aatcatgcta ttgttggctg
     1441 tggtatccat cccaactggg ataaaaatga gaattgtcca gtggcttatc cacgctatca
     1501 gatgttgatg gattatttga atttgagtag aaatattatt aaatcagatt tacatcattt
     1561 ccctgaatat ggtactttta tctgtgggag ccaggttcag ctggatattt caaaaaccaa
     1621 ctacttacgg gtgattaatg cttttactca aattgaagcg gctaaggctt atttatttgc
     1681 aaactctgaa ttttcgggtg cggattggga tacgaaaatt tcaagggata ttttctggga
     1741 agaatctatg catggtatct atccagagaa tgttggggtc aatgctagac tccttaatga
     1801 tgaagctgat ttttttgact atctaaatca ttctgcgatt tttactgcgg aacgtgatgg
     1861 gcagacctat tatttttatc ctattcaggc tggggactat ttggctacgt ccgaaatcca
     1921 agcatttgct ctgaatgggg atgaggttat tatttacccc caagagaagg attttgaaac
     1981 tcatcgtagt taccagtacc aagatttaac gactcgagga acagttgagt ttcgtagtgt
     2041 gtgtacacag ccacttgata ggacttttgc ttctgcagct tttcacttgg gattattggt
     2101 taatttagac aagttagaag cttacttaga aacagcacct ttctttaaag tatttggtta
     2161 tgattacaag tctttaagga gacaattttc taagaaaaat cttacagatg aggaagaaac
     2221 tacgattatt gaattttcca aagacttact cctactagct gaggagggac tagtggtgag
     2281 aaataaggaa gaaatgacct atttacagcc tttgagagaa gaattgagcc tataatttct
     2341 cttataaagg gagaattttc tgaaaaatca tgatataatg gacgagacta tagataaagg
     2401 atagagagta atgacattag tttatcaatc aacgcgtgat gccaacaata cagtaactgc
     2461 cagccaagca attttgcaag gtttggcgac ggacggcggt ttgtttacac cggttactta
     2521 tccaaaggta gatttggact ttgacaaatt gaaagatgct tcttaccagg aagttgctaa
     2581 gctagttttg tcagcatttt tagatgactt tacagctgag gagttggact actgtatcaa
     2641 caatgcctac gatagcaaat ttgatactcc agctattgca ccattagtga aattagatgg
     2701 gcaatacaat ttggaacttt tccatggttc aacgattgcc tttaaggata tggccttgtc
     2761 tattttgcca tactttatga cgactgctgc taagaaacat ggtttggaga acaagattgt
     2821 tatcttgaca gcgacatctg gtgacacggg gaaagctgct atggcggggt ttgcggatgt
     2881 gcctggtact gagattatcg tcttttatcc aaagggtggt gtcagcaagg tacaagagtt
     2941 gcaaatgacc actcagaatg gtgacaatac tcatgttatt gctattgatg gtaattttga
     3001 cgatgcgcaa acaaatgtga agcacatgtt taacgacgtg gctcttcgtg aaaaattgac
     3061 taccaacaag ttgcaatttt catcagctaa ctctatgaac attggtcgtc tggtgccaca
     3121 aattgtttgt tatgtttatg cttacgctca attggttaag actggtgaaa ttgtagctgg
     3181 tgaaaaggtt aacttcacag taccaacagg aaactttgga aatatcttgg ctgcctttta
     3241 tgccaaacaa atcggcctac cagttggcaa gctaatctgt gcttcaaatg acaataatgt
     3301 cttgacagac ttctttaaaa cacgtgtcta tgacaaaaaa cgtgagttta aggtaacaac
     3361 cagcccatct atggatatct tggtatcttc aaacttggag cgcttgattt tccatctttt
     3421 gggaaataat gctgaaaaga cagctgaact tatgaatgcc ttgaacacgc aaggacaata
     3481 taagttgaca gactttgatg cagagatttt ggacctcttt gcagctgaat atgcgactga
     3541 ggaagaaaca gcggcagaaa tcaagcgtgt ttatgagtca gattcttata ttgaggatcc
     3601 acatacggcg gttgcctcag cagtttatag aaaataccaa gcggttactg gagatgtaac
     3661 taagacagtg attgcttcaa cagctagtcc atacaagttc ccagtagttg cagtagaagc
     3721 tgtaactgga aaagcaggtt tgacagactt tgaagccttg gctcaattac atgaaatctc
     3781 aggcgttgca gtgccaccag cagttgatgg gcttgaaata gctccaattc gtcacaagac
     3841 aacagtggca gctgctgaca tgcaagcagc ggttgaggct tatttaggac tttaagacag
     3901 agggagcaaa ctcggttggg aaaccaactg agtttctttt catcaggagg agagattgtt
     3961 taagaaaaat aaagacattc ttaatattgc attgccagct atgggtgaaa actttttgca
     4021 gatgctaatg ggaatggtgg acagttattt ggttgctcat ttaggattga tagctatttc
     4081 aggggtttca gtagctggta atattatcac catttatcag gcgattttca tcgctctggg
     4141 agctgctatt tccagtgtta tttcaaaaag catagggcag aaagaccagt cgaagttggc
     4201 ctatcatgtg actgaggcgt tgaagattac cttactatta agtttccttt taggattttt
     4261 gtccatcttc gctgggaaag agatgatagg acttttgggg acggagaggg atgtagctga
     4321 gagtggtgga ctgtatctat ctttggtagg cggatcgatt gttctcttag gtttaatgac
     4381 tagtttggga gccttgattc gtgcaacgca taatccacgt ctgcctctct atgttagttt
     4441 tttatccaat gccttgaata ttcttttttc aagtctagct atttttgttc tggatatggg
     4501 gatagctggt gttgcttggg ggacaattct gtctcgtttg gttggtcttg tgattttgtg
     4561 gtcacaatta aaactgcctt atgggaagct aacttttggt ttagataagg aactgttgac
     4621 cttggcttta ccagcagctg gagagcgact tatgatgaga gctggagatg tagtgatcat
     4681 tgccttggtc gtttcttttg ggacggaggc agttgctggg aatgcaatcg gagaagtctt
     4741 gacccagttt aactatatgc ctgcctttgg tgtcgctatg gcaacggtca tgctgttggc
     4801 ccgagcagtt ggagaggatg attggaaaag agttgctagt ttgagtaaac aaaccttttg
     4861 gctttctctg ttcctcatgt tgcccctgtc ctttagtata tatgtcttgg gtgtaccatt
     4921 aactcatctc tatacgactg attctctagc ggtggaggct agtgttctag tgacactgtt
     4981 ttcactactt ggtaccccta tgacgacagg aacagtcatc tatacggcag tctggcaggg
     5041 attaggaaat gcacgcctcc ctttttatgc gacaagtata ggcatgtggt gtatccgcat
     5101 tgggacagga tatctgatgg ggattgtgct tggttggggc ttgcctggta tttgggcagg
     5161 gtctctcttg gataatggtt ttcgctggtt atttctacgc tatcgttacc agcgctatat
     5221 gagcttgaaa ggataggaaa tgcaaaaaac agcttttatt tgggatttag acgggacttt
     5281 attggactct tacgaagcga ttttatcagg gattgaggag acttttgctc agttttctat
     5341 tccttatgat aaggagaagg tgagagagtt tatcttcaag tattcggtgc aaaatttgct
     5401 tgtgcgggtg gcagaagata gaaatctgga tgttgaggtg ctaaatcagg tgcgtgccca
     5461 gagtctggct gagaagaatg ctcaggtagt tttgatgcca ggtgcgcgtg aggtgctagc
     5521 ttgggcagac gaatcaggaa ttcagcagtt tatatatact cataagggga acaacgcttt
     5581 taccattctc aaggacttgg gggtggaatc ctattttaca gagattttaa ccagtcagag
     5641 tggctttgtg cggaagccaa gtccagaagc ggctacctat ctgctagata agtatcagtt
     5701 gaattctgat aatacttatt atatagggga tcggactctg gatgtggaat ttgcccagaa
     5761 tagtgggatt caaagtatca actttttaga gtctacttat gaagggaatc acaggattca
     5821 agcgttagca gatatttccc gtatttttga gactaagtga taaaaagatt gtgtcagttt
     5881 tgtgacagag acctaacaaa ctatttcaag taatctagtt tgttacaagg aatagacagt
     5941 tctgttaaat aggcccgaga gggctttttt tctacatttt ttgtgttatg atagacaggt
     6001 actcatttga aaggaatttg aaggaatgaa gaaaagaatg ttattagcgt caacagtagc
     6061 cttgtcattt gccccagtat tggcaactca agcagaagaa gttctttgga ctgcacgtag
     6121 tgttgagcaa atccaaaacg atttgactaa aacggacaac aaaacaagtt ataccgtaca
     6181 gtatggtgat actttgagca ccattgcaga agccttgggt gtagatgtca cagtgcttgc
     6241 gaatctgaac aaaatcacta atatggactt gattttccca gaaactgttt tgacaacgac
     6301 tgtcaatgaa gcagaagaag taacggaagt tgaaatccaa acacctcaag cagattctag
     6361 tgaagaagtg acaactgcga cagcagattt gacaaccaat caagtgaccg ttgatgatca
     6421 aactgttcaa gttgcagatc tttctcaacc aattgcagaa gctccaaaag aagtagcatc
     6481 aaattcagaa gttgcagaga cagtgactgc tgcagaagaa gtggcactat ctacagactc
     6541 tactacgcca gagggacaac cagccgaaac aactagtcca gttgaagaag tagctcctca
     6601 ggcaacgact ctagctgaga agcaggaaac acaagtgagc tctcaaaccg agtcagcagt
     6661 ggaagcaact acaatgccag tagaagaaaa agcaaccgaa gcaactacaa caagttcaga
     6721 agcaaaagaa gtagcatcat caaatggagc tacagcagca gtttctactt atcaaccaga
     6781 agagacgaaa ataatttcaa caacttacga ggctccagct gcgcccgatt atgctggact
     6841 tgcagtaaca aaatctgaaa atgcaggtct tcaaccacaa acagctgcct ttaaagaaga
     6901 aattgctaac ttgtttggca ttacatcctt tagtggttat cgtccaggag acagtggaga
     6961 tcacggaaaa ggtttggcta tcgattttat ggtaccagaa cgttcagaat taggggataa
     7021 gattgcggaa tatgctattc aaaatatggc cagccgtggc attagttaca tcatctggaa
     7081 acaacgtttc tatgctccat tcgatagcaa atatgggcca gctaacactt ggaatccaat
     7141 gccagaccgt ggtagtgtga cagaaaatca ctatgaccac gttcacgttt caatgaatgg
     7201 ataaacccga cttggtaaca tcattttgac gaatgagatc tagctttcgt gataggaagc
     7261 gattctcgtt cgttttttct ttgtcatact cttcgaaaat ctcttcaaac aacgtcagtt
     7321 ttatctgaaa cctcaaagct gtgctttgag caacctgcga ctagcttcct agtttgcttt
     7381 ttgattttca ttgagtatca atttgaatgg aaaatggaaa gttatcatct tgtaatgagt
     7441 taagcaacat tcttgcaatc tattttatag tagattgaaa ctagaatagt acacaactgc
     7501 ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct gctcttattt
     7561 catttcacta tactttatat tataattgac tggtcaaata ttgataaatc aataaaaaga
     7621 gaggggaaga aatgctagag attcaagatt tactgtatca actccgcttg tctgagcaag
     7681 tgagtacgca attgtttgaa aaagcttggg attagtttga cacggtatca gattttactg
     7741 tttttgctgg agcattctcc ttgtaaccaa atggcggttc aggagcgttt gaaaattgat
     7801 caggctgctt tgacacggaa tttcaagatt ttggaaacgg aaggtttggt ggagcgtcat
     7861 cgtaatcctg aaaatcagcg ggaagtattg gtagaggctg cgaagtatgc caaggagcag
     7921 ttagtggtga atccccctct gcagcatatc aaggttaagg aagagatgga aagtatctta
     7981 acagagtttg agagaacaga actcagccgt ttattaaata aattggtttt gggtattgaa
     8041 aatatagaaa tttaaggaga aatagatgtc aattattaca attattttaa caacgatcgt
     8101 tgctttggag catttttaca ttttttattt ggaaagtatt gccacgcaat cagatgcgac
     8161 tagtcgtgta tttaatatgg aaaaggaaga attggctcat ccgtcagtaa gttcattgtt
     8221 caaaaatcaa gggatttata aggctctgct aggagtcttt ctcttgtatg tcatttattt
     8281 ctcacagaat ttagaaattg tgactatttt tgtcttattt gtgattggtg ctgcgactta
     8341 cggctcttta acagcggata aaaaaattat tttgaagcaa ggtggatcag ctattttggc
     8401 cttgattagt attttactct ttaaatacac ttgaaggtcg attttaatct cgctaatcct
     8461 ttttaatcca gaataaggga aatatgttat acttgttttt aagaaaaaag tctcattgaa
     8521 ttggttttga ggagttagaa atgaaagtat tagtgacagg ttttgagccc tttggagggg
     8581 aaaagggcaa tccaactttg gaggccatta aaggtttacc agctgaaatc catggtgctg
     8641 aggtccgttg gctagaggtg ccgacagttt ttcacaaatc tgctcaagta ttggaagaag
     8701 agatgaatcg ttatcaacct gactttgtcc tttgtattgg gcaagctggt ggaagaacta
     8761 gtgtgacacc tgaacgagtg gccattaatc aagacgatgc acgcatttct gataacgaag
     8821 ataatcaacc gattgaccgt cccattcgcc cagatggtgc ttcggcctac tttagtagtt
     8881 tgccgattaa agcgatggtt caagctataa aaaaagaggg cttaccggcc tctgtttcca
     8941 atacggcagg gacttttgtc tgcagccatt tgatgtatca ggctctctat ttggtagaaa
     9001 agaaatttcc atatgttaag gcaggtttta tgcatattcc ttatatgatg gaacaggtgg
     9061 tgaacagacc gactactcca actatgagtt tagtggatat tcggcgaggg atagaagcag
     9121 caatcggcgc tatgatagaa catggagatc aggaactcaa gttggtaggc ggagaaactc
     9181 attgatagaa aaaagcttga ggggaaaaac cttcaagctt ttggacgttt tcgagccaat
     9241 actgctcggt aaaacataat tttagtgcat tggatataag gtaggagtga aaaactagca
     9301 atgccaaagg taatccaatt gaggaagtac caaggaagaa gctgtaaatc taggacaaag
     9361 tgctggaact tgtagccctt cataaaggaa cggctagttt ttaggattcg tcttggtggg
     9421 acctgtccta ggtctagact ataacagaga agaaattcca cctgtgaata ggcataatac
     9481 tgtggaatat agaggatatt tcctacaatg atcaagatga gacttgcaag aaagtagagt
     9541 ccaaagacca tgaggaaacg ctcggtttca actgatgaga gatctagatt tggaaactca
     9601 ggatgtaggg tgacgaattt tttggctaaa aagctactat aaaagaggag gtaaatccca
     9661 agtaaattag ggatactcca taaaaagaga tagaaacgtt tgagaagtag ggtcaaaaag
     9721 gtttgagaaa agcgctcctc atcaaagaga gctaggctgt tttttacaga tggctccgtt
     9781 ttagaatctt tcatgagtgt cagtgttgca tagacggaac tggtcaaaag aatagtcccg
     9841 ataaaggaga ctagtagagg aaagaggtag gtttgaagta tttggccaag tatgctgaaa
     9901 aatggctgtt ctaaaacagt cccgtggatc cgagataagg gattaagaaa accagataag
     9961 atgaccagca tactgggaag gatatagagg agaaagagac ggggggtgtc agcctgaaaa
    10021 tgttttgact cctgacgaat tgtttttaaa tcaatttttg gatagttcat tctcttatta
    10081 taccatagtt cttatacata gttcgtgaca gttcctactt tttttgataa aatcatacag
    10141 tgtgtccttg ggcacactgt atgaactggg actgtctttc ccagcttcgg aggtaaaaaa
    10201 tgtcagattc accaatcaaa tatcgtttga ttaagaaaga aaaacacaca ggagctcgtc
    10261 taggagaaat catcactccc cacggtacct ttccgacacc tatgtttatg ccagttggga
    10321 cacaagccac tgtcaaaact cagtcacctg aagaattgaa ggagatgggt tcgggaatta
    10381 tcctatcaaa cacctatcat ctctggcttc gccctggaga tgaactcatt gcacgcgctg
    10441 gtggtctcca caagttcatg aattgggacc agcctatctt gacagatagt ggtggttttc
    10501 aggtttattc tttagcagat agccgtaata tcacagaaga aggagtaacc tttaaaaatc
    10561 atctaaatgg ttctaagatg ctcctatccc cagaaaaagc catctctatt cagaataatc
    10621 tgggttcaga catcatgatg tcctttgatg aatgtcctca gttttatcaa ccttatgact
    10681 acgttaagaa atcgatcgag cgtaccagcc gttgggctga gcgtggtttg aaggctcacc
    10741 gtcgtccaca tgaccaaggt ttgtttggaa ttgtgcaagg tgcaggattt gaagaccttc
    10801 gccgccaatc agctcacgat cttgtcagca tggatttctc aggctactct atcggtggtt
    10861 tggcagtggg agaaacccat gaagagatga atgcggtctt ggactttaca actcaactgc
    10921 tgcctgaaaa taaacctcgt tatctgatgg gtgtgggagc gccagatagc ttgatcgatg
    10981 gggtcattcg tggggtggat atgtttgact gtgtcttacc gactcgaatt gctcgtaacg
    11041 ggacttgtat gaccagtcaa ggacgtttgg ttgtgaaaaa tgcccagttt gctgaggact
    11101 ttacgccact ggatcctgag tgtgattgct acacatgtaa taactataca cgcgcttacc
    11161 ttcgtcacct gctcaaggct gatgaaacct ttggtatccg cttgactagc taccacaatc
    11221 tttacttctt gcttaacctg atgaagcaag tgcgacaagc catcatggat gacaatctct
    11281 tggaattccg taagtatttt gtggaaaaat atggctataa taagtcagga cgtaatttct
    11341 aaaatggaat tgatataagc taaaaatcct aagttttctc ttaggatttt tcttcttttt
    11401 ttgatagaat aaagtgtaca atgaaaggaa gaataaactc gtatgcgcat taaatggttt
    11461 tccttgatta ggattatagg tttacttttg gtactcttgt atcacttctt tcagacgatc
    11521 tttcctggag gatttttcgg ggtagatgtc tttttcacat tttcaggttt cctgattaca
    11581 gctctactca ttgaagaatt ttctaagaac aatgagattg atttgatagg attttttaga
    11641 agacgctttt atcggattgt gccacctgtg gttttgatgg tcttggtgac catgcctttt
    11701 actttcttgg ttcgccaaga ctatgttgct ggaattggtg gccagattgc gggcgtctta
    11761 ggctttatga ccaacttcta tgaactctta acaggtggga gttatgaatc tcagttcatt
    11821 cctcatttgt ttgttcataa ttggagtttg gcagttgagg ttcactacta tattctttgg
    11881 ggattggcag tttggttctt atccaaacaa gctaaatcaa atggtcagtt gaaggggatg
    11941 atctttctct tatctgctac tgccttcttg atcagtttct tctccatgtt tattggtagt
    12001 tttctagtga cctcttattc ctctgtttat ttctccagtt taactcatgt ctatccattc
    12061 tttttgggaa gtatgttagc aactattgta ggcgttcgtc agacgacttc cctcgtcaag
    12121 cagttggata aaatctggga tttacgaaag actttagtag tttttggagg aggctttggt
    12181 ttcctagttc ttttgacttt ctttgtcaaa ttcacttatc tttttgccta tcttatcggc
    12241 ttcttgcttg ccagtcttgc agctcttgcc atgattctgg cggcgcgtgt cttacatgaa
    12301 aagacacatc atatacagga gccgaagatt atcagctttt tagcggatac tagctatgcg
    12361 gtttatcttt tccattggcc tttctatatc attttctcac agttgacatc aaatcttctt
    12421 gctgtattac tgactctgat ttgttcttat ggctttgcca gtctgtcatt ttatgtattg
    12481 gaaccttgga ttgcaggcaa gaacacacct attttacaaa ctcttcgtcc cctgccttat
    12541 attcacgcaa ttcttgcagc aggtacagga atcttgacct tcattgtctg catggtgacc
    12601 ttgttggcac cacaagtggg agcgtttgag acagacttga ctgtcaatgg cttgaagcaa
    12661 gctgcaacaa atattggcca gaccaaggtg atggcagaac gggcagatgc aaacagtttg
    12721 ggaattgctg atggcactat gttaattggt gactcagtgg ctttaagggc aaatacagca
    12781 ctacagacag ctcttcctgg agcacagatt aacgcgcagg tcagcgtaac aaccaagacc
    12841 gcaaatgaaa tcatgctaaa taatagccag aataaatttt tacctaagac ggtggtcatt
    12901 gcgactgggg taaataatcc tgagaattac aaggatgact gggacagtat cgtgaaaaat
    12961 cttcctaagg gacaccatat gattttggtg actccttatg agggtgataa gacaaaagag
    13021 acctatgcca tcgttgagaa ggctgctgcc tatatgagag aattggcaga gaagacacct
    13081 tacattacga tagcagattg gaatcaagtt gcgaaagagc atccagaaat ttgggctgga
    13141 acagaccagg ttcatttcgg gagtgagagt agcactatcg aagcaggagc aaaattgtat
    13201 gcagatacga ttgccacagc tttgcagaca gctcaagaca agccggttaa atcaaaataa
    13261 cttgtattaa aaaagagaag agttggagaa atccagctct tttaaaatat ctccaaaaaa
    13321 taggtctata ccatttacaa ataaaaaaga aaggtttata atgtaattga cataataaat
    13381 tgtagaatca atcttttaag gaggttaaca ttatgcctaa ctatattaaa gcggatcagt
    13441 ttttctaccc acacggagtt cgtcgaggtg gttacttgga acttgtggac ggcaagtttg
    13501 gaaaacatgt agagcagatt cctgaagggg ctgaggtgat tgactataca ggttatagca
    13561 ttgccccagg tcttgtggat actcatattc atggatatgc aggtgtagat gtgatggaca
    13621 acaacattga aggtacattg catactatga gtgaaggact tcttagtacc ggtgttacca
    13681 gtttcttacc cacaacttta acagccactt atgagcaatt gcttgcagtc actgaaaatc
    13741 ttggaaacca ttataaagaa gcaacaggtg ctaagattcg tgggatttat tatgaaggtc
    13801 catatttcac agaaactttt aagggggcac aaaatccaac ttatatgaga gacccgggtg
    13861 ttgaggagtt tcattcttgg caaaaagcgg caaatggctt gcttaataaa attgcccttg
    13921 caccagaacg tgatggggtg gaagactttg ttcgtacagt tacgggcgaa ggtgtgacgg
    13981 ttgctcttgg acattcaaac gcgacttttg atgaagccaa aaaagcagtc gatgctggag
    14041 cgagtgtttg ggtgcatgcc tacaatggaa tgcgtgggtt gactcaccgt gaattgggta
    14101 tggttggagc catgtaccaa ttgccacata cctatgcaga gttgatctgt gatggtcacc
    14161 acgtagatcc aaaggcttgc gaaattctta tcaaacaaaa aggaacagaa aacatcgctc
    14221 ttatcacaga ctgtatgaca gctgggggat tggaagacgg agattatatg ttgggagaat
    14281 tcccagttgt cgttgcaaat ggaactgcac gcctcaaatc gacaggtaac ttggcaggtt
    14341 ctatcctcaa actcaaagat ggtttgaaga atgtggtcga atggggaatt gcgaatccgc
    14401 atgaagcagt catgatggcc agcttcaacc cagctaaatc cgttcacatc gatgacgtct
    14461 gtggccaaat ccgtgaaggc tacgacgctg acttcatcgt attagataaa gatttggaat
    14521 tggtagcaac ctacctagat ggcgtgaaac gttatcaagc ataagagaga aggcagaagt
    14581 tagagactaa cttctgcttt tttatacagg gtactttact ggtaaataaa aagttaaaaa
    14641 aatcacaaaa aaagcttgaa gaaacaaaga aaaatgctta caattgaact ataaatatta
    14701 caaataaaaa aacggaggag tgctttatga aagcctatac ttatgttaaa ccaggacttg
    14761 cttcttttgt tgatgtagac aaaccagtta ttcgcaagcc aacagacgct attgtgcgta
    14821 ttgtaaaaac cactatttgt ggaacagacc tccatattat caaaggggat gttcctactt
    14881 gccaaagtgg taccattctt ggccacgaag ggattgggat tgttgaagaa gttggggaag
    14941 gagtttccaa cttcaaaaaa ggtgacaagg tcttgatttc ttgcgtctgt gcctgtggta
    15001 aatgctacta ctgtaaaaaa ggaatttatg cccactgtga agacgaaggg ggctggattt
    15061 tcggtcactt gattgatggt atgcaggctg aatatctacg tgtccctcat gcagataata
    15121 ctctttacca tactccagaa gacttgtcag atgaagcttt ggttatgctg tcagacattc
    15181 tgcctactgg atatgaaatt ggtgtcttaa aagggaaagt agaacctggt tgcagcgtag
    15241 ccattattgg ttcaggtcca gttggattgg ctgctctttt aacagcccaa ttctattcac
    15301 cagctaaatt gattatggta gacctagacg ataaccgctt ggaaactgcc ctatcattcg
    15361 gtgcgactca taaggttaat tcttcagacc ctaaaaaagc cattaaagaa atttatgatt
    15421 tgacagatgg tcgtggtgtg gatgtcgcta tcgaagctgt agggattcct gaaacatttg
    15481 atttctgtca aaagattatc ggtgtagacg gaacggttgc caactgtggt gtgcatggta
    15541 aaccagttga attcgattta gataaacttt ggattcgcaa catcaatgta acaactggtt
    15601 tggtatctac aaatacgact ccacaattgt tgaaagcact tgaaagtcat aagattgaac
    15661 cggaaaaatt ggtaactcac tatttcaaac tcagtgaaat tgaaaaagcc tacgaagtct
    15721 tcagtaaggc agcagaccac catgccatta aggtcattat cgaaaacgat atctcagaag
    15781 cctaagtagt aaaaatattt ttgtacataa gcaaatagaa attcagtcat ccatcagatg
    15841 gctggatttt ttatcaaaaa attaagaaat gagcatattt ctttccttgt ctggcggaat
    15901 tggttataat atacggtaca aaggaatgaa tgaatatgta tcgtgttata gaaatgtacg
    15961 gagattttga accgtggtgg ttcttagaag gttgggaaga agatattgta gcaagtagaa
    16021 aatttgacca gtattatgat gctctcaaat actacaaaac ttgctggttt agattggaac
    16081 aagaatcccc tctttataaa agtagaagcg acttgatgac cattttttgg gacccggaag
    16141 accaacgctg gtgtgatgaa tgtgatgagt atttacaaca ataccattct ttggctcttt
    16201 tgcaggatga gcaggttatc ccagacgaaa aactacgctc aggctatgaa aaacaaacca
    16261 gtcaggaaag gaatcgttct tgccgtatga aattaaaata gagaaaagta acttttttgg
    16321 agttgctttt tttatttttc taacgctttg cgaatagtat aggtgaggag gtaagtatgg
    16381 ttcaagaaat tgcacaagaa atcattcgtt cagctcggaa aaaagggacg caggatattt
    16441 attttgtccc taagttagac gcctatgagc ttcatatgag ggtaggagac gagcgctgta
    16501 aaattggtag ctatgatttt gaaaagtttg cagccgttat cagtcacttt aagtttgtgg
    16561 cgggtatgaa tgtgggagaa aaaagacgta gtcaactggg ttcctgtgat tatgcctatg
    16621 accagaagat ggcgtctcta cgtttatcta ctgtaggcga ttatcgggga catgagagtt
    16681 tggttatccg tttgttgcac gatgaggagc aggacttgca tttttggttt caggatattg
    16741 aagaattagg caagcagtac aggcaacggg gactctatct ttttgctggc ccggttggga
    16801 gtggtaagac gaccttgatg catgaattgt ccaagtcact ctttaaagga cagcaagtta
    16861 tgtccatcga agatcctgtc gaaatcaagc aggacgacat gcttcagttg cagttgaacg
    16921 aagcaatcgg cctaacctat gaaaatctaa tcaaactttc cttgcgtcat cgaccagatc
    16981 tcttgattat cggagaaatt cgtgacagcg agacggcgcg tgcagtggtc agagctagtt
    17041 tgacaggtgc gacagtcttt tcaaccattc acgccaagag tatccgaggt gtttatgagc
    17101 gtctgctgga gttgggtgtg agtgaagaag aattggcagt tgttctgcaa ggagtctgct
    17161 accagagatt aatcggggga ggaggaatcg ttgactttgc aaacagagat tatcaagaac
    17221 accaagcagc caagtggaat gagcaaattg accagcttct taaagatgga catatcacaa
    17281 gtcttcaggc tgagacggaa aaaattagct acagctaagc aaaaaaatat catcacccta
    17341 tttaacaatc tcttttctag cggttttcat ctggtggaga ctatctcctt tttagatagg
    17401 agtgctttgt tggacaagca gtgtgtgatc cagatgcgtg tgggcttgtc tcaggggaaa
    17461 tcattctcag aaatgatgga aagtttggga tgttcaagtg ctattgtcac tcagttatcc
    17521 ctagctgaag ttcatggcaa tctccacctg agtttgggaa agatagaaga atatctggac
    17581 aatctggcca aggtcaagaa aaaattgatt gaagtagcga cctatccctt gattttgctg
    17641 ttttttcttc tcttaatcat gctggggcta cggaattacc tgctcccaca actggatagt
    17701 agcaatattg ccacccgaat tatcggtaat ctgccccaaa tttttctagg catggcaggg
    17761 cttgtttccg tgcttgccct tttagcacta actttttata aaagaagttc taagatgaat
    17821 gtcttttcta tcttagcacg ccttcccttt attggaatct ttgtgcagac ctatttgaca
    17881 gcctattatg cacgtgaatg ggggaatatg atttcacagg gaatggagtt gacgcagatt
    17941 tttcaaatga tgcaggaaca aggttcccag ctctttaaag aaatcggtca agatctggct
    18001 caaaccctga aaaatggccg tgaattttct cagacgatag gaacctatcc tttctttagg
    18061 aaggaattga gtctcatcat agagtatggg gaagttaagt ccaagctggg tagtgagttg
    18121 gaaatctatg ctgaaaaaac ttgggaagcc ttttttaccc gagtcaaccg caccatgaat
    18181 ttggtgcagc cactggtttt tatctttgtg gcactgatta tcgttttact ttatgcggca
    18241 atgctcatgc ccatgtatca aaatatggag gtaaattttt aaaatgaaaa aaatgatgac
    18301 attcttgaaa aaagctaagg ttaaagcttt tacattggtg gagatgttgg tggtcttgct
    18361 gattatcagc gtgcttttct tgctctttgt acctaatctg accaagcaaa aagaagcagt
    18421 caatgacaaa ggaaaagcag ctgttgttaa ggtggtggaa agccaggcag aactttatag
    18481 cttggaaaag aatgaagatg ctagcctaag caagttaaaa gacgatgggc gaatcacgga
    18541 agaacaggtt aaagcttata aagaatacaa tgataaaaat gtaggagcaa atcgtaaagt
    18601 caatgattaa ggcctttacc atgctggaaa gtctcttggt tttgggtctt gtgagtatcc
    18661 ttgccttggg cttgtccggc tctgttcagt ccacttttgc ggcagtagag gaacagattt
    18721 tctttatgga atttgaagaa ctctatcggg aaacccaaaa acgcagtgta gccagtcagc
    18781 aaaagactag tctgaactta gatgggcaga cgattagcaa tggcagtcaa aagttgccag
    18841 tccctaaagg aattcaggtc ccatcaggcc aaagtattac atttgaccgt gctgggggca
    18901 attcgtccct ggctaaggtt gaatttcaga ccagtaaagg agcgattcgc tatcaattat
    18961 atctaggaaa tggaaaaatt aaacgcatta aggaaacaaa aaattagggc agtgatttta
    19021 ctggaagcag tagtcgctct agctatcttt gccagcattg cgaccctcct tttgggacaa
    19081 attcaaaaaa ataggcaaga ggaagcaaaa atcttgcaaa aggaagaagt cttgagggta
    19141 gctaagatgg ccttgcagac ggggcaaaat caggtaagca tcaacggagt tgagattcag
    19201 gtattttcta gtgaaaaagg attggaggtc taccatggtt cagaacagtt gttggcaatc
    19261 aaagagccat aaggtcaagg cttttacctt gttagaatcc ctgcttgccc tcattgtcat
    19321 cagtggggga ttactccttt ttcaagctat gagtcagctc ctcatttcag aagttcgcta
    19381 ccagcaacaa agcgagcaaa aggagtggct cttgtttgtg gaccaacttg aggtagaatt
    19441 agaccgttcg cagttcgaaa aagtagaagg caatcgccta tacatgaagc aagatggcaa
    19501 ggacatcgcc atcggtaagt caaagtcaga cgattttcgt aaaaccgatg ctagtggacg
    19561 ggggtatcag cctatggttt atggcctcaa atcagctcag attacagagg acaatcaact
    19621 ggttcatttt cgtttccagt ttcaaaaagg cttagaaagg gagttcatct atcgtgtgga
    19681 aaaagaagaa agttaaggca ggtgttctcc tctatgcagt caccatggca gctatcttta
    19741 gtcttttgtt gcaattttac ttgaaccgac aagtcgccca ctatcaagac tatgctttga
    19801 ataaagaaaa attggttgct tttgccatgg ctaaacgaac caaggataaa gccgagcaag
    19861 aaagtgggga acaggtcttt aatctaggtc aggtaagcta tcaaaacaag aaaacaagct
    19921 tggtgacgac tgttcgtacg tctaagagcc aatatgagtt tctgtttcct tcagtcaaaa
    19981 tcaaagaaga gaaaagagat aaaaaggaag aggtagcgac cgattcaagc gaaaaagtgg
    20041 agaagaaaaa atcagaagag aagcctgaaa agaaagagaa ttcctagtca attcaactat
    20101 aatgcgttga atcaagaata gtccactata gtttctagaa aattgctgga aatggatgtt
    20161 aagctccaat tcatttgttt atatcttatt tcagtttact atactttgtg ctaaattaaa
    20221 gatatgaaac atgattttaa ccacaaagca gaaactttcg attcccctaa aaatatcttc
    20281 ctcgcaaact tggtatgtca agcagccgag aaacagattg atcttctatc agacaaagaa
    20341 attttagatt tcggtggtga cacgggtcta ttagccttgc ccctagcccc tagccaagca
    20401 ggctaagtca gtcactcttg tagacatttc tgagaaaatg ttggagcaag ctcgtttgaa
    20461 agtggagcag caagcaatca agaatatcca gtttttggag caagatttac cgaaaaatcc
    20521 cttggagaaa gagtttgatt gccttgctgt tagtcgggtt cttcatcata tgcctgattt
    20581 ggatgcggct ctctcactgt ttcatcaaca tttgaagtaa gatgggaaac tcatcattgc
    20641 tgattttacc aagacagaag ctaatcatca tggatttgat ttagctgaac tggaaaacaa
    20701 gctaattgag catggttttt catctgtgca tagtcagatt ctctatagcg ctgaagactt
    20761 gtttcaagga aatcactcag aattcttttt aatagtagcc caaaaatcac tcgcctagtc
    20821 agggagtgat ttttctataa ggatggaaaa aagaagggaa atttgataag ataggaatat
    20881 ggattttgaa aaaattgaac aagcttatac ctatttacta gagaatgtcc aagtcatcca
    20941 aagtgatttg gcgaccaact tttatgacgc cttggtggag caaaacagca tctatctgga
    21001 tggtgaaact gagctaaacc aggtcaaaga caacaatcag gcccttaagc atttagcact
    21061 acgcaaagaa gaatggctca agacctacca gtttctcttg atgaaggctg ggcaaacaga
    21121 acccttgcag gccaatcacc agtttacacc ggatgctatt gctttacttt tggtgtttat
    21181 tgtggaagag ctgtttaaag aggaggaaat tactatcctc gaaatgggtt ctgggatggg
    21241 aattttgggc gctactttct tgacctcgct tactaaaaag gtggattatt tgggaatgga
    21301 agtggatgat ttgctgattg atttggcagc tagcatggca gatgtaattg gtttgcaggc
    21361 tggctttgtc caaggagatg ccgttcgtcc acaaatgctc aaagaaagtg atgtggtcat
    21421 cagcgacttg cctgttggct attatcctga tgatgccgtt gcgtcgcgcc atcaagttgc
    21481 ttctagtcaa gaacatactt acgcccatca cttgctcatg gaacaaggac ttaagtacct
    21541 caagtcagac ggatacgcta tttttctagc tccgagtgat ttgttgacca gtcctcaaag
    21601 taatttgttg aaagtctggt tgaaagagga ggcaagtctg gttgctatga ttagtttacc
    21661 tgaaaatctc tttgctaatg ctaaacaatc taagactatt tttatcctac agaagaaaag
    21721 tgaaatagca gtagagcctt ttgtttatcc acttgctagc ttgcaagatg caagtgtttt
    21781 aatgaaattt aaagaaaatt ttcaaaaatg gactcaaggt actgaaatat aaaatagatt
    21841 ttgttataat agttgaaaac gcttaaaaag gggtatcatg ttatgacaaa aacaattgca
    21901 atcaatgcag gaagttcaag tttgaaatgg caattatact taatgccaga agaaaaagta
    21961 ttggcgaaag gtttgattga acgtatcggt ttgaaagatt caatttcaac tgtaaaattt
    22021 gacggccgtt ctgaacaaca aattttggat attgaaaatc atacacaagc tgttaaaatt
    22081 ttattggatg acttgattcg tttcgatatt atcaaggctt atgacgagat tacaggtgtt
    22141 ggacatcgtg ttgttgctgg tggagaatat ttcaaagaat caacagttgt tgagggagat
    22201 gttttagaaa aagttgaaga gttgagtttg ttggctcctc tacacaaccc ggcaaatgca
    22261 gcaggtgttc gtgccttcaa ggaattgttg ccagacatta ccagtgtagt tgtttttgat
    22321 acttccttcc acacaagtat gccagagaaa gcttatcgct accctctacc aacaaaatat
    22381 tacacagaaa acaaggttcg taaatacggt gctcatggta caagtcacca gtttgtagca
    22441 ggagaagctg caaaactctt gggacgtcca ttagaagact tgaagttaat tacctgtcat
    22501 attggtaacg gaggctcaat tacagctgtg aaagccggca aatctgtaga cacttctatg
    22561 gggttcactc ctcttggtgg tattatgatg ggaacgcgta caggggatat tgatccagct
    22621 atcattcctt atttaatgca atatacagag gattttaaca caccagaaga tatcagtcgt
    22681 gttcttaacc gtgaatcagg tcttttggga gtttctgcta attctagcga tatgcgcgat
    22741 atagaagcag ctgtagcaga agggaatcac gaggctagct tggcttatga aatgtatgtt
    22801 gaccgtatcc aaaaacatat cggtcagtac cttgcagtgc taaatggagc agatgccatt
    22861 gttttcacag caggtgtcgg tgaaaatgca gagagtttcc gtcgtgatgt aatctcaggg
    22921 atttcgtggt ttggttgtga tgttgatgat gaaaagaatg tctttggcgt tacaggagac
    22981 atctcaacag aggcagctaa aatccgtgtc ttggttattc caacagatga agaattagtc
    23041 attgcccgtg acgttgaacg cttgaaaaaa taagtgaaac taaaaaaata ttcaatacaa
    23101 ggagttggga aagttatttt tccagcttct ttttctgatg aaattgtcca aaaccttgct
    23161 atgattggct tttttgaaaa atatggtata atagtagtaa tttaatagat ggagttgagt
    23221 tttgaagaaa aactttcgtg taaaaagaga gaaagatttt aaggcgattt tcaaggaggg
    23281 gacaagtttt gctaatcgca aatttgtggt ctaccaatta gaaaaccaga aaaaccattt
    23341 tcgagtaggt ctatcagtta gcaaaaaact ggggaatgcc gtcactagaa atcaaattaa
    23401 gcgacggatt cggcatatta tccagaatgc aaaagggagt ctggtagaag atgtcgactt
    23461 tgttgtcatt gctcgaaaag gagtcgaaac cttgggatac gcagagatgg agaaaaatct
    23521 actccatgta ttaaaattat caaagattta ccgggaagga aatgggagtg aaaaagaaac
    23581 taaagttgac tagtttgcta ggactgtctc tgttaatcat gacagcctgt gcgactaatg
    23641 gggtaactag cgatattaca gccgaatcgg ctgatttttg gagtaaattg gtttacttct
    23701 ttgcggaaat cattcgcttt ttatcgtttg atattagtat cggagtgggg attattctct
    23761 ttacggtctt gattcgtaca gtcctcttgc cagtctttca ggtgcaaatg gtggcttcta
    23821 ggaaaatgca ggaagctcag ccacgcatta aggcgcttcg agaacaatat ccaggtcgag
    23881 atatggaaag cagaaccaaa ctagagcagg aaatgcgtaa agtatttaaa gaaatgggtg
    23941 tcagacagtc agactctctt tggccgattt tgattcagat gccggttatt ttggccctgt
    24001 tccaagccct atcaagagtt gactttttaa agacaggtca tttcttatgg attaaccttg
    24061 gtagtgtgga tacaaccctt gttcttccga ttttagcagc agtattcacc tttttaagta
    24121 cttggttgtc caacaaagct ttgtctgagc gaaatggcgc tacgactgcg atgatgtatg
    24181 ggattccagt cttgattttt atctttgcag tttatgcgcc aggtggagtc gccctatact
    24241 ggacagtgtc taatgcttat caagtcttgc aaacctattt cttgaataat ccattcaaga
    24301 ttatcgcaga gcgcgaggcc gtagtacagg cacaaaaaga tttggaaaat agaaaaagaa
    24361 aagccaagaa aaaggctcag aaaacgaaat aaataaggag gaatctggta atggtagtat
    24421 ttacaggttc aactgttgaa gaagcaatcc agaaaggatt gaaagaatta gatattccaa
    24481 gaatgaaggc tcatatcaaa gtcatttcta gggagaaaaa aggctttctt ggtctatttg
    24541 gtaaaaaacc agcccaagtg gatattgaag cgattagtga aacgactgtt gtcaaagcaa
    24601 atcaacaggt agtaaaaggc gttccgaaaa aaatcaatga tttgaacgag cctgtgaaga
    24661 cggttagtga agaaaccgtt gaccttggtc atgtggttga tgctattaaa aaaatagagg
    24721 aagaaggtca aggtatttct gatgaagtca aggctgaaat cttaaaacat gaaagacatg
    24781 ccagcactat cttagaagaa actggtcaca ttgagatttt aaatgaactt caaatcgagg
    24841 aagcgatgag ggaagaagca ggcgctgatg accttgaaac tgagcaagat caaactgaaa
    24901 atcaagactt gaaagagatg ggcttgaagg tcgagcaaag ttatgatatt gcccaggtgg
    24961 ctacggatgt gactgcctat gttcaagcga ttgtggatga catggatgtt gaagctacac
    25021 tttcaaatga ttataaccgt cgtagcatca atctacaaat tgacaccaac gaaccaggtc
    25081 gtattatcgg ctaccatggt aaagtcttga aggccttgca actgttggct caaaattatc
    25141 tttacaaccg ctattccaga accttctacg ttacaatcaa tgtcaatgat tatgtcgaac
    25201 accgtgcaga agtcttgcag acctatgcgc aaaaattggc gactcgtgtt ttggaagaag
    25261 ggcgcagtca taaaacagat ccaatgtcaa atagcgaacg caagattatc catcgtatta
    25321 tttcacgtat ggatggcgtg actagttact ctgaaggtga tgagccaaat cgctatgttg
    25381 ttgtagatac agaataagta aaatcaggtt tatcctgatt ttttgctagt tagaggaggt
    25441 taaactgatg ttgaataaga taagagacta tttagacttt gctggtttgc agtaccgtaa
    25501 tcctgataaa gcgggagcag agcgagagaa gatgctggca ttccgccaca aaggacaaga
    25561 ggcccgaaag gcttttacag aactggccaa agcctttcaa gcaagccatc cagaatggca
    25621 actccaacag actagccagt ggatgaatca ggcccagcgt ttgagaccac atttttgggt
    25681 ttatctacag agagacggac aagtgacaga acctatgatg gccttacgtt tgtatgggac
    25741 atctactgac tttggaattt ctttggaagt cagtttcatc gaacgtaaga aggatgagca
    25801 aacactgggc aagcaggcca aagttttaga cattccaacc gttaaaggga tttattatct
    25861 aacctactct aatggtcaaa gtcaacggtg ggaggcgaat gaagaaaagc gtcgtacttt
    25921 acgcgagaag gtgagaagtc aagaagttcg aaaagtttta gtgaaggtag atgttcctat
    25981 gacagaaaat tcgtctgaag aagaaatcgt agaaggctta ttgaagtctt attctaaaat
    26041 tcttccctat tatctagcta cgagaaaata agataatttg taaaacatca taaatcatac
    26101 agtccaagag tgaacagtcc gctgtgtaat tcttggtctt tttgtttgcg ctttcgcatt
    26161 atataataaa cttacaaaaa caattcaaaa ggagaacaat tatggaagtc gtttcaagtg
    26221 ttctaaattg gttttctagc aatattttgc agaatcccgc atttttcgta ggtttattgg
    26281 tgttgatagg atatgcactt ttgaaaaaac ctgcccatga cgttttttca gggtttgtta
    26341 aagcaacagt agggtatatg ttgcttaacg tgggtgctgg tggtttggtt acaacctttc
    26401 gtccaatctt agcagctctt aactacaaat tccaaattgg tgcagcggtt atcgaccctt
    26461 actttggact tgctgcagca aacaacaaaa ttgcagcaga gtttccagat tttgttggaa
    26521 ctgcaactac agctctattg attggttttg gaataaatat cttgctcgta gctcttcgaa
    26581 agattacgaa ggtaagaacc ctctttatta ctggtcacat catggtacaa caagctgcaa
    26641 cagtatctct tatggttcta ttcttagtac cacaattgcg caatgcttac ggtacagcag
    26701 cgattggtat catctgtgga ctttactggg cagttagttc aaatatgact gttgaggcaa
    26761 ctcaacgctt gactggtggt ggcggatttg cgattggtca ccaacagcaa tttgcaatct
    26821 ggtttgtaga taaagtagca ggacgctttg gtaagaaaga agaaagttta gacaatctta
    26881 aattacctaa gttcctctca atcttccacg atacagttgt tgcatctgct accttgatgc
    26941 tcgtattctt cggagccatt cttttaatct tgggtccaga cattatgtct aataaagaag
    27001 tcatcacttc aggaactcta ttcaatcctg ctaaacaaga tttctttatg tacattatcc
    27061 aaacagcctt taccttctca gtttacttgt tcgttttgat gcaaggtgtc cgaatgttcg
    27121 tatctgagtt gacaaacgcc ttccaaggta tttcaaacaa attgttgcca ggttcattcc
    27181 cagcggttga cgttgcagct tcttatggat ttggttctcc aaatgctgtc ttgtcaggat
    27241 ttacctttgg tttgattggt caattgatta caattgtctt gctcatcgtc tttaaaaatc
    27301 cgattcttat tattacagga tttgtaccag tgttctttga caatgcagcc attgcggtct
    27361 acgctgataa acgcggcgga tggaaagcgg ctgttatcct ttcctttata tcaggtgtcc
    27421 ttcaagttgc tctaggagct ctttgtgtgg cccttctcga tttggcatct tatggtggct
    27481 accatggaaa tatcgacttt gaattcccat ggcttggatt tggatatatc ttcaaatacc
    27541 ttggtattgt tggttatgta cttgtgtgtc tcttcttgct tgttattcct caacttcaat
    27601 ttgccaaagc aaaagataaa gagaaatatt acaacggtga agttcaagaa gaagcttagt
    27661 atctagaaaa ggagaaataa aatggttaaa gtattagcag cgtgcggaaa tggaatgggt
    27721 tcatcaatgg ttatcaagat gaaggttgaa aatgctctcc gtaagcttaa tcaaacagat
    27781 tttacagtca attcatgcag tgtcggtgaa gctaaaggtt tagcagtagg atatgacatc
    27841 gtaatcgctt ctcttcattt gattcaagaa ttggaagggc gaactaatgg gaagttaatt
    27901 ggtcttgata acttgatgga tgataaagaa atcaccgaaa aactcagtca agcactacag
    27961 taaaaggttg gagggggctg gacagaaact gagagttatc gtttctgtcc ttctccctct
    28021 ttaaataaag gaggcagata tgaatttaaa acaagcttta attgacaatg actcgatccg
    28081 actaggttta gaggctaaca attggaaaga agcagtcaag gtagcagtag atcccctaat
    28141 tgaaagtggg gcaattttgc cagagtatta cgatgctatc attgaatcga ctgaagagta
    28201 tgggccttac tatatcttga tgccaggtat ggctatgccc cacgctagac ctgaagctgg
    28261 tgtgcaaagt gatgcctttt cattgattac cttacaaaat cctgttgtat tttcagatgg
    28321 gaaagaggta tctgttttgt tggcactagc agcaacaagt tcaaaaattc acacaagtgt
    28381 agccattcca caaattattg ccctgtttga attagaagat tctattgcac gtttacaggc
    28441 ttgccagact aaagaagatg tcttggctat gattgaagaa tctaaggata gcccttatct
    28501 cgaaggattg gatttggaaa gttagaaaga ggaataaaga aatgacaaaa agaataccta
    28561 atttacaagt tgcattagac cattcagact tgcaaggagc gattaaagca gctgtttctg
    28621 ttggtcagga agtagatatt atcgaagctg gaactgtttg cttgcttcaa gttggaagtg
    28681 aactggctga agtcttgcgt agccttttcc cagataagat tattgtggca gacacaaaat
    28741 gtgctgatgc tggtggaaca gttgctaaaa ataatgcggt tcgtggagca gactggatga
    28801 cttgtatctg ttgtgcaacc atccctacta tggaagcagc tctaaaggct atcaagactg
    28861 aacgaggaga acgaggcgaa atccagatcg agctttatgg cgattggact tttgaacaag
    28921 ctcagctttg gctagatgca ggtatctcac aagctattta tcaccaatct cgtgatgctc
    28981 ttcttgctgg tgaaacttgg ggtgaaaaag accttaataa ggttaaaaaa ctcattgaca
    29041 tgggcttccg tgtatctgta acaggtggtc tagatgtaga tactctcaaa ctctttgaag
    29101 gtgttgatgt ctttaccttt atcgcaggtc gtggaattac agaggctgcg gatccagcag
    29161 gagcagcgcg tgccttcaag gatgaaatca aacgaatttg ggggtaaatc atggtacgtc
    29221 caattggaat ttatgaaaag gcaaccccaa cacactttac ttggctagaa cgtttaaatt
    29281 ttgccaagga gttaggcttt gattttgtcg agatgtctat tgacgaacgt gacgagcgtt
    29341 tagcaagact tgactggagt aaggaagaac gcttggaagt tgtcaaagca atctatgaaa
    29401 ctggtgttcg tattccttct atctgttttt caggccatcg tcgctaccca ttgggttcaa
    29461 aagatccagt tctagaggaa aaatctctag aactcatgaa aaaatgtatc gaattagctc
    29521 aagacttggg agttcgtacg attcaattag ctggttacga tgtttactat gaggaaaagt
    29581 caccccagac acgccaacgt tttatcaaaa atttgagaaa agcctgtgac tgggctgaag
    29641 aagctcaggt ggtacttgct attgaaatta tggatgatcc tttcatcagt agcatcgaaa
    29701 aatatttggc tatagaaaaa gagattgact ctcccttcct ctttgtatat ccagatattg
    29761 gtaatgtgtc tgcatggcat aatgatatct atagtgagtt ttatcttggt catcatgcca
    29821 tcgcagctct ccatctcaag gatacttatg cagtgacaga aagttcaaag ggccagttcc
    29881 gagatgtacc tttcgggcaa ggttgtgtca aatgggaaga agctttcgat attttaaagg
    29941 aaaccaatta taatggacct ttcctaatcg aaatgtggtc tgaaaattgt gaaacagtag
    30001 aagaaacacg cgcagccgtt caagaggcgc aagcttttct ctatccactc attaagaaag
    30061 caggtttgat gtaagatgaa tcaagtaatc aatgctatgc gtaaacgagt ctgtgatgcc
    30121 aatcaatcat tgccaaaaca tggacttgtc aaatttacct gggggaatgt atctgaagtt
    30181 aatcgcgaac tcggtgtcat tgttatcaaa ccatcaggcg tggattatga cgaattgaca
    30241 cctgaaaaca tggtagtgac tgatctagat ggtaagatcc tagaagggga tttaagacca
    30301 tcttccgacc tcccaactca tgtgcaatta tataaggctt ggtcagaaat tggtagtgtg
    30361 gttcacaccc attcgacaga agctgttggt tgggctcagg caggtcgtga tattcctttc
    30421 tacggaacaa cccatgcaga ttatttctac ggttcaatcc cttgcgcccg tagtttgacc
    30481 aaggacgaag tagaagtggc ctatgaaaaa gatactggcc tggttatcgt agaagagttt
    30541 gaacatcgcg gacttaaccc ggttgaagta ccaggaattg ttgtacgcaa tcacggtcca
    30601 ttcacctggg gcaaaaatcc agagaatgct gtttatcact ctgtcgtact agaggaagta
    30661 tcaaagatga atcgctttac agaacaaatc aatccaagag ttggacctgc tccccagtac
    30721 atactagaaa aacactacca acgtaaacat ggaccaaatg cttattatgg tcaaaagtaa
    30781 gaacgatgaa ggaggagaaa aagataaatt tagctcctct ttttacattt gatttttatt
    30841 gagagtaaag ttggaattga agtaatttta aaagattttt tagaaatagc gcttgatata
    30901 tatatggtaa aataaaaaga attgctgtga tatcaataga tttgggggat tttttaatat
    30961 ggtactggat aaggcaagtt gtgatttgct tcaatatttg atggatcaag aaacgtccaa
    31021 aacgattatg gcgatttcga aagatttgaa agagtcaaga aggaaaattt attatcacat
    31081 tgacaaaatc aatgctgctc tgggtgacga ggcgcttcac atcattagta ttccacgaat
    31141 tggtattcac ttaacggaag agcagagaga tgcttgttgt aaactattat cggaagtaga
    31201 ttcgtacgat tatatcatga gtgcgcatga acgtatgatg ataatgttac tatggatagg
    31261 tatttctaaa gaacgtatta cgattgaaaa attgatagag ttaacagagg tatctaggaa
    31321 tactgttctc aatgatttga atagtattcg ttatcaacta actttggaac aatatcaggt
    31381 gatcttgcaa gtgagcaagt cacagggata ccaccttcat gcccaccctc ttaataaaat
    31441 tcagtatctt caatcgcttc tatatcatat ttttatggaa gaaaatgcca cttttgtatc
    31501 tattttagaa gataagatga aagagaggtt agatgatgag tgtttgcttt ctgttgaaat
    31561 gaaccaattt tttaaggaac aggttccttt agttgaacaa gatttaggga agaaaataaa
    31621 ccatcatgaa ataactttta tgttgcaggt tctaccttat ttgctgttaa gctgtcataa
    31681 tgttgaacag tatcaagaaa gacatcagga tatagagaaa gaattttctt tgataagaaa
    31741 aagaatagag tatcaggtgt ctaagaaatt aggagaacgg ttgtttcaaa agtttgaaat
    31801 ttctttgtca ggacttgaag tttctcttgt agctgttctc ctcctctcct atcgtaaaga
    31861 tttggatatt catgcagaaa gtgatgattt tcggcaatta aaacttgctt tagaagaatt
    31921 tatctggtat tttgaatcac aaatccgaat ggagattgag aacaaggatg atttgttacg
    31981 aaatttgatg atccactgta aagccttgtt atttagaaag acttacggta ttttttctaa
    32041 aaatcctcta acaaaacaaa ttcgatccaa gtatggagaa ttatttttag tcactagaaa
    32101 atctgcggaa attttagaag gagcatggtt tattcggcta acagacgatg atattgccta
    32161 tttgacgatt catattggag gatttttaaa atatacacca tcgtctcaaa aaaatatgaa
    32221 aaaagtttat ctcgtttgtg atgaaggtgt tgcggtttcg agacttttgc tgaaacaatg
    32281 caaactttat tttccaaatg agcaaattga cactgtattt acaacagaac aatttaagag
    32341 tgtggaagat attgcacaag ttgatgtagt gattactact aatgatgatt tggatagcag
    32401 atttccgatt ttaagggtta atcctatcct tgaagcagaa gatattttga aaatgctaga
    32461 ctatcttaaa cacaatatat ttcgtaataa gagcaaaagt ttcagtgaaa atctttctag
    32521 tcttatttcg tcttatattg tagatagcaa gttggctagt aagttccaag aagaggttca
    32581 aacacttata aatcaagaaa tagtagttca agcttttttg gaagatattt gaaggacagt
    32641 ccaatgatga acacaaacct gtgtttttct tggtcttttt tagtgttttg aagggtggta
    32701 tactaatctc aaagataaca attatatcca aaggaggcaa catatgccaa acgtcaaaga
    32761 aattacaaga gagtcatgga ttttagccac tttcccagag tggggaacat ggttgaacga
    32821 agaaatcgaa gaagaagtcg tacctgaagg caactttgcc atgtggtggc taggcaactg
    32881 tggtacttgg attaagacac cagctggtgc taacgttgtc atggaccttt ggtcaaaccg
    32941 tggaaaatca accaaaaaag tgaaagatat ggttcgtggg caccaaatgg caaatatggc
    33001 aggtgttcgt aagttgcaac caaacttgcg tgttcagcca atggttatcg atccatttgc
    33061 tatcaacgaa ctagactatt acttagtttc acacttccac agtgatcata tcgacccata
    33121 cacagctgca gcaattctca acaatcctaa gttagagcat gttaagttta tcggtcctta
    33181 ccactgtgga cgaatctggg aaggatgggg tgttccaaaa gaacgtatca tcgttgttaa
    33241 accaggtgac actatcgaat taaaagatat gaagattcat gcagtagaat catttgaccg
    33301 tacttgcttg gtaactctcc cagtgaacgg tgctgatgag acaggcggtg aacttgctgg
    33361 cttggctgtt acagatgaag aaatggctca aaaggctgtt aactatatct ttgaaacacc
    33421 aggtggaacc atctatcatg gtgcagattc tcacttctca aactattttg caaaacatgg
    33481 taaagacttt aaaattgatg ttgctttgaa taactatggt gaaaatccgg taggtatcca
    33541 agacaaaatg acatctatcg accttcttcg tatggcagaa aatctgcgta ccaaagtcat
    33601 tatcccagtt cactatgata tctggtctaa cttcatggct tctactaatg agattctaga
    33661 actttggaaa atgcgaaaag atcgcttgca atacgatttc catccattta tctgggaagt
    33721 tggcggtaag tacacttatc ctcaagatca acacttagta gaataccatc atccacgtgg
    33781 ttttgatgat tgttttgaac aagactctaa cattcaattt aaagctttgc tataatataa
    33841 aaatattctt tggaggttat ccgtatgttg catgatacgg ataattttca tataatagta
    33901 aaatagaatg tgtgattcaa taatcacctc aaatagaaag gaaattctat gtcaaatcta
    33961 tctgttaatg caattcgttt tctaggtatt gacgccatta ataaagccaa ctcaggtcat
    34021 ccaggtgtgg ttatgggagc ggctccgatg gcttacagcc tctttacaaa acaacttcat
    34081 atcaatccag ctcaaccaaa ctggattaac cgcgaccgct ttattctttc agcaggtcat
    34141 ggttcaatgc tcctttatgc tcttcttcac ctttctggtt ttgaagatgt cagcatggat
    34201 gagattaaga gtttccgtca atggggttca aaaacaccag gtcacccaga atttggtcat
    34261 acggcaggga ttgatgctac gacaggtcct ctagggcaag ggatttcaac tgctactggt
    34321 tttgcccaag cagaacgttt cttggcagcc aaatataacc gtgaaggcta caatatcttt
    34381 gaccactata cttacgttat ctgtggagac ggagacttga tggaaggtgt ctcaagcgag
    34441 gcagcttcat acgcaggttt gcaaaaactt gataagttgg ttgttcttta tgattcaaat
    34501 gatatcaact tggatggtga gacaaaggat tcctttacag aaagtgttcg tgaccgttac
    34561 aatgcctacg gttggcatac tgccttggtt gaaaatggaa cagacttgga agccatccat
    34621 gctgctatcg aaacagcaaa agcttcaggc aagccatctt tgattgaagt gaagacggtt
    34681 attggatacg gttctccaaa caaacaagga actaatgctg tacacggcgc ccctcttgga
    34741 gcagatgaaa ctgcatcaac tcgtcaagcc ctcggttggg actacgaacc atttgaaatt
    34801 ccagaacaag tatatgctga tttcaaagaa catgttgcag accgtggcgc atcagcttat
    34861 caagcttgga ctaaattagt tgcagattat aaagaagctc atccagaact ggctgcagaa
    34921 gtagaagcca tcatcgacgg acgtgatcca gtcgaagtga ctccagcaga cttcccagct
    34981 ttagaaaatg gtttttctca agcaactcgt aattcaagtc aagatgcctt gaatgttgtg
    35041 gcagctaaat taccaacctt cctaggtgga tcagctgacc ttgctcactc aaacatgact
    35101 tatatcaaga cggatggact tcaagacgat accaatcgct tgaatcgtaa cattcagttt
    35161 ggtgttcgtg aatttgcaat gggaacaatc ttgaacggga tggcccttca tggtggactt
    35221 cgtgtatacg gtggaacttt cttcgtcttc tctgactatg tgaaggcagc tgtccgtttg
    35281 tcagccttac aaggacttcc tgtgacttat gtctttaccc atgattcaat cgcagttggg
    35341 gaagatggtc cgactcacga accagttgag catttagcag gtcttcgtgc tatgccaaat
    35401 ctaaatgttt tccgtccagc agatgcgcgt gaaacgcaag cagcttggta ccttgcagtg
    35461 acaagtgaga aaacaccaac tgcccttgtc ttgacacgtc aaaacttgac tgttgaagat
    35521 ggaacagact tcgacaaggt tgctaaaggt gcttatgttg tatatgaaaa tgcagccgac
    35581 tttgatacca tcttgattgc gacaggttca gaggttaatc ttgctgtctc agctgctaaa
    35641 gaattggcta gtcaaggcga aaaaatccgc gtagtcagca tgccatctac agatgtcttt
    35701 gataaacaag atgcagctta caaggaagaa attcttccaa atgcagtccg ccgtcgtgtt
    35761 gcagtcgaaa tgggtgcaag tcaaaactgg tacaaatatg ttggtctcga tggtgccgtt
    35821 ctaggtattg ataccttcgg agcctctgcc ccagcaccaa aagtattggc agaatatggc
    35881 tttactgtcg aaaatcttgt aaaagttgtt cgaaatttga aataatccta aaaatcaggg
    35941 cgtaagctct ggtttttctt accagaaaag taaggtacaa tcttgtaaaa gtagctgaaa
    36001 tttgatatag tagtcctatg taaaagacaa aggagaaaac aatgaatcca aatattactt
    36061 ttttaatcat gcttgtaggt atgatggcct tgatgttctt tatgcaacgt tctcaaaaga
    36121 aacaagctca aaagcgtatg gaaagcttaa ataaactaca aaaaggctat gaagtgatta
    36181 caatcggtgg actttatgga acagtcgatg aagtagatac ggagaaggga acaatagttc
    36241 ttgacgtaga tggagtttac ttgacttttg aactagctgc tatcaagaca gtattaccgc
    36301 tgaaagaaac agcttcacta gaaggcgcaa ttgaaaaata agacgggatc acgaactccc
    36361 gttttctata aaagaaagga aatgggatga aaaaattagt ctttgtctgt ctgggaaata
    36421 tttgccgtag ccctatggcc gagtttgtta tgaaatcaat gacagataac tacgaaatcc
    36481 aaagtcgagc aacttcctct tgggaacatg gcaatccgat tcataagggg actcagggaa
    36541 tttttcaaga gtatgagatt ccttatgaca agaacaagac atcgcttcag attagtaagg
    36601 aagattttga agcctttgat tatattatcg gaatggacgc ttcaaatatt tctgacttac
    36661 gtcagatgtg tccagtagac tgtcaagata agatttactc attttcatct gaaagtgttc
    36721 cagacccttg gtatacagga gattttgaag aaacctatcg acgtgttcaa gagggctgtc
    36781 aagcttggtt agaacgttta gaaaaggaga gttaaggtgg aaaatcttac gaatttttac
    36841 gaaaagtatc gtgtctatct gactcgtcca cgtttagagc ttttggcagt agttaccatt
    36901 gttttctgtg ctgtactcgt cttttttcta aatattccag gaaaaggtgt cttaaaactc
    36961 gataatggaa cgattgttta tgatggcagt cttgtccgtg gtaaaatgaa tggccaaggt
    37021 accattacct tccaaaatgg agaccaatat acaggtggct tcaacaatgg agccttcaac
    37081 ggaaaaggta cctttcaatc taaagaaggc tggacctacg aaggtgattt tgtaaatggt
    37141 caggctgaag gaaaagggaa actaacaaca gaacaagaag tcgtttatga aggaactttt
    37201 aaacaaggcg tttttcaaca aaaataaagc ctcctatcaa aggaggtatt attagaatca
    37261 caaggtaagc gcttacctgt gaatcccttt ctttccaaat ccctcttcca agcaagtttg
    37321 tgaaataaaa aatatttgaa ataaatttca caaacttcaa agataaaact tgataagaaa
    37381 agaaaatgag aaaagtttca caagagttta aaaattcttt gtgaaatgtt tatgaaactg
    37441 tttacaaagt tgaaataatg cgttataata aacttgtgaa aaaattaaca aaggatatcg
    37501 ttccttgaaa gctatggagg aaaatatggc tgataaaaaa actgtgacac cagaggaaaa
    37561 gaaactcgtt gctgaaaaac acgtagatga gttggttcaa aaagctctag ttgcccttga
    37621 agaaatgcgt aaattggatc aagaacaagt tgactacatc gttgccaaag catcagtagc
    37681 agctttggat gcccacggag aattggcttt acatgccttt gaagaaacag gacgtggtgt
    37741 atttgaagac aaagcaacta agaacttgtt tgcttgtgaa cacgtagtaa acaacatgcg
    37801 ccacactaag acagttggcg ttatcgaaga agacgatgta acaggattga ctcttattgc
    37861 tgaaccagtt ggtgttgttt gtggtattac tccaacaaca aacccaacat caacagcaat
    37921 cttcaaatca ttgatttcat tgaagacacg taacccaatc gtctttgcct tccatccatc
    37981 agcacaagaa tcatctgctc atgcagctcg tatcgtccgc gatgcagcta tcgcagctgg
    38041 tgctcctgaa aactgtgtac agtggatcac tcaaccatct atggaagcaa ctagtgccct
    38101 tatgaaccac gaaggtattg caacaatcct tgcaacaggt ggtaatgcca tggttaaagc
    38161 cgcatactca tgtggtaaac cagctcttgg ggtaggtgcc ggaaacgttc cagcttatgt
    38221 tgaaaaatca gcaaacattc gtcaagcagc acacgatatc gtcatgtcta aatcatttga
    38281 taacggtatg gtctgtgcat ctgaacaagc agttatcatt gataaagaaa tttacgatga
    38341 atttgtagca gagttcaaat cttaccacac ttactttgta aacaaaaaag aaaaagctct
    38401 tcttgaagag ttctgcttcg gcgtcaaagc aaacagcaaa aactgtgctg gtgcaaaatt
    38461 gaacgctgac atcgttggta aaccagcaac ttggattgca gaacaagcag gatttacagt
    38521 tccagaagga acaaacattc ttgctgcaga atgtaaagaa gttggcgaaa atgagccatt
    38581 gactcgtgaa aaattgtcac cagttattgc agttttgaaa tctgaaagcc gtgaagatgg
    38641 tattactaag gctcgtcaaa tggttgaatt taacggtctt ggacactcag cagctatcca
    38701 cacagctgac gaagaattga ctaaagaatt tggtaaagct gttaaagcta ttcgtgttat
    38761 ctgtaactca ccttctactt ttggtggtat cggggacgtt tacaatgcct tcttgccatc
    38821 attgacactt ggatgtggtt cttacggacg caactcagtt ggggataacg ttagtgccat
    38881 taacctcttg aatatcaaaa aagtcggaag acggagaaat aacatgcaat ggatgaaact
    38941 tccttcaaaa acatactttg aacgtgattc aattcaatac cttcaaaaat gtcgtgacgt
    39001 tgaacgtgtc atgatcgtta ctgaccatgc catggtagag cttggtttcc ttgatcgtat
    39061 catcgaacaa ctggaccttc gtcgcaataa ggttgtttac caaatctttg cggatgtaga
    39121 accggatcca gatatcacaa ctgtaaaccg tggtactgag attatgcgtg ccttcaaacc
    39181 agataccatc atcgcactcg gtggtgggtc tccaatggat gctgccaaag taatgtggct
    39241 cttctacgag caaccagaag tggacttccg tgaccttgtc caaaaattca tggatatccg
    39301 taaacgtgcc ttcaagttcc cattgcttgg taagaagact aaattcatcg cgattccaac
    39361 tacatctggt acaggatctg aagtaacacc atttgccgtt atctctgata aagcaaacaa
    39421 ccgtaaatac ccaatcgctg actactcatt gacaccaact gtggcaatcg tagatcctgc
    39481 tttggtattg acagttccag gatttgttgc tgctgatact ggtatggacg tattgactca
    39541 cgcgacagaa gcatacgtat cacaaatggc tagtgactac actgatggtt tagcacttca
    39601 agccattaaa ttggtctttg aaaatctcga aagctcagtt aagaatgcag acttccactc
    39661 acgtgagaaa atgcataacg cttcaacaat cgctggtatg gcctttgcca atgccttcct
    39721 aggtatttct cactcaatgg cccataagat tggtgcgcaa ttccacacaa tccacggtcg
    39781 tacaaatgct atcttgcttc catacgttat ccgttacaac ggtacacgtc cagctaagac
    39841 agcaacatgg cctaagtaca actactaccg tgcagatgaa aaataccaag atatcgcacg
    39901 catgcttgga cttccagctt ctactccaga agaaggggtt gaatcttacg caaaagctgt
    39961 ctacgaactc ggtgaacgta ttgggatcca aatgaatttt agagaccaag gaattgacga
    40021 aaaagaatgg aaagaacatt ctcgtgaatt agccttcctg gcttatgaag accaatgttc
    40081 accagctaac ccacgtcttc caatggtaga ccatatgcaa gaaatcatcg aagatgcata
    40141 ctatggctac aaagaaagac caggacgccg taaataattg tttatcagtc tagaagcaag
    40201 acaaaaactc aatttgaggg aaagatccag tactttttct atgataaaag gcatcctatc
    40261 aaggtttttg aacacctgat aggatgcctt tttatgatat tgaggccttt ttgccctttt
    40321 tgaaaaacta gaatagaaac aaaatatata atagattgaa actggaatag tacacttctg
    40381 cttctaaaac attgttagaa ttcgatttga ctgtcctgat cgatttgtcc tgttcttatt
    40441 tcattttaat atataaaaaa tat
//
LOCUS       DAVBOU010000015        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBOU010000015 DAVBOU010000000
VERSION     DAVBOU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.015"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ879_000859"
     CDS             complement(56..1066)
                     /locus_tag="VQ879_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3143034.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ879_000860"
     CDS             1215..2384
                     /locus_tag="VQ879_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3143035.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ879_000861"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ879_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3143036.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ879_000862"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ879_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3143037.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ879_000863"
     CDS             4146..4379
                     /locus_tag="VQ879_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3143038.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VQ879_000864"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VQ879_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VQ879_000865"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VQ879_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3143039.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5863..8016
                     /locus_tag="VQ879_000866"
     CDS             5863..8016
                     /locus_tag="VQ879_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3143040.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8029..9378
                     /locus_tag="VQ879_000867"
     CDS             8029..9378
                     /locus_tag="VQ879_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3143041.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9548..10255
                     /locus_tag="VQ879_000868"
     CDS             9548..10255
                     /locus_tag="VQ879_000868"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3143042.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10457..14182
                     /locus_tag="VQ879_000869"
     CDS             10457..14182
                     /locus_tag="VQ879_000869"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3143043.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14275..15717
                     /locus_tag="VQ879_000870"
     CDS             14275..15717
                     /locus_tag="VQ879_000870"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3143044.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15754..16776
                     /locus_tag="VQ879_000871"
     CDS             15754..16776
                     /locus_tag="VQ879_000871"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3143045.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16773..17318
                     /gene="purN"
                     /locus_tag="VQ879_000872"
     CDS             16773..17318
                     /gene="purN"
                     /locus_tag="VQ879_000872"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3143046.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17402..17911
                     /locus_tag="VQ879_000873"
     CDS             17402..17911
                     /locus_tag="VQ879_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3143047.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17936..19483
                     /gene="purH"
                     /locus_tag="VQ879_000874"
     CDS             17936..19483
                     /gene="purH"
                     /locus_tag="VQ879_000874"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3143048.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19605..20867
                     /gene="purD"
                     /locus_tag="VQ879_000875"
     CDS             19605..20867
                     /gene="purD"
                     /locus_tag="VQ879_000875"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3143049.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21270..21758
                     /gene="purE"
                     /locus_tag="VQ879_000876"
     CDS             21270..21758
                     /gene="purE"
                     /locus_tag="VQ879_000876"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3143050.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21745..22836
                     /gene="purK"
                     /locus_tag="VQ879_000877"
     CDS             21745..22836
                     /gene="purK"
                     /locus_tag="VQ879_000877"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3143051.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22846..23073
                     /locus_tag="VQ879_000878"
     CDS             22846..23073
                     /locus_tag="VQ879_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3143052.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23136..24434
                     /gene="purB"
                     /locus_tag="VQ879_000879"
     CDS             23136..24434
                     /gene="purB"
                     /locus_tag="VQ879_000879"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3143053.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ879_000880"
     CDS             complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ879_000880"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3143054.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28740..29456)
                     /locus_tag="VQ879_000881"
     CDS             complement(28740..29456)
                     /locus_tag="VQ879_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3143055.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29804..31591
                     /locus_tag="VQ879_000882"
     CDS             29804..31591
                     /locus_tag="VQ879_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3143056.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31588..32064
                     /locus_tag="VQ879_000883"
     CDS             31588..32064
                     /locus_tag="VQ879_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3143057.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32092..32997
                     /locus_tag="VQ879_000884"
     CDS             32092..32997
                     /locus_tag="VQ879_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3143058.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32984..33799
                     /locus_tag="VQ879_000885"
     CDS             32984..33799
                     /locus_tag="VQ879_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3143059.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33806..34210
                     /locus_tag="VQ879_000886"
     CDS             33806..34210
                     /locus_tag="VQ879_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3143060.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34509..35675
                     /locus_tag="VQ879_000887"
     CDS             34509..35675
                     /locus_tag="VQ879_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3143061.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35791..36828
                     /locus_tag="VQ879_000888"
     CDS             35791..36828
                     /locus_tag="VQ879_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3143062.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37035..37889
                     /locus_tag="VQ879_000889"
     CDS             37035..37889
                     /locus_tag="VQ879_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3143063.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38039..38279
                     /locus_tag="VQ879_000890"
                     /pseudo
     CDS             38039..38279
                     /locus_tag="VQ879_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10751 a         7406 c         9115 g        11139 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagatagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggcattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaag aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ctagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggt ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga gaccttggca gctgttttac
     1801 gcaagtatga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccagac tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct gggcttatgt cgactttgcc gactgtagat
     3541 gggaagggat ttgacatgct agacctcggt gccaatgcgg aaaatacagc ccagcacctc
     3601 catcaatacg cggttctagg atccttctat gctaaaaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggct tgctcaataa cggaacagag agtagcaagg gcgatccgct tcgtaaggaa
     3721 acttatgaat tactagtggc tgatgaaagt ttgaacttta tcggaaatgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacaac tcaattattc agatattggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaatc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt ctatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaatagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgtctaggg
     5521 tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagt actcttgttc
     5581 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
     5641 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
     5701 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
     5761 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     5821 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     5881 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     5941 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     6001 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt tgagacgcga
     6061 gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc ttttgttgcc
     6121 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggat
     6181 agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc acgtgagcgt
     6241 tttgaggaag aatggacagg agtgactctt tttatggcac ctagtccaga ctataagcct
     6301 tataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     6361 ttgattgcca atatcgtttt ggcaacactc ttggtaaccg ggattaacat tgtgggttct
     6421 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacactaggg
     6481 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     6541 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     6601 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     6661 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     6721 ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca aaataccaat
     6781 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     6841 aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct gtcttcttct
     6901 atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     6961 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     7021 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     7081 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     7141 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     7201 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     7261 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgaccttc
     7321 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     7381 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     7441 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     7501 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     7561 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     7621 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     7681 atgccactga attaccagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     7741 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     7801 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     7861 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     7921 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     7981 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     8041 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     8101 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agagaaggag
     8161 atgagtttgt ccactagagc tactgtcgaa cctagtcgta ttcttgcaaa tatccagtca
     8221 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     8281 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     8341 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     8401 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     8461 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     8521 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     8581 gaggctaaaa ttcgcgatta ccagacagct aagtcagcta ttgaaacagg tgcttccttg
     8641 gccggtcaga atctagccta ctctttttac cagtcctaca agtctcaggg cgaggaaaat
     8701 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     8761 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     8821 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     8881 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     8941 cttttagaca aggggaaaat tacggcgagt gaggatgggg tgcttcatct taatcctgag
     9001 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     9061 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     9121 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca acttttccta
     9181 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     9241 aaaatcgagg cggagactaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     9301 gaaggccgct tgcagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     9361 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     9421 agattcttct tgcagttttt tctttacaat ttttgaaaaa tatctactat ttattcggtt
     9481 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     9541 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     9601 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca atggtgtcaa
     9661 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     9721 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     9781 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     9841 ttccttttca aaacgttttg gtgtggatga aggaatcgcc ttggagactc cgattgtcga
     9901 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     9961 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
    10021 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
    10081 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
    10141 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
    10201 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
    10261 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
    10321 ccttttcact ctgtagagaa ctaggtgaac taaccgatgt ttacgaaatt gtctaggaaa
    10381 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10441 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10501 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10561 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
    10621 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10681 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10741 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10801 caacacagcc caactttact tggtgaataa agatattgat gtgactgagt tggaagctgt
    10861 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
    10921 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
    10981 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    11041 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    11101 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11161 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11221 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11281 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11341 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11401 ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg agccatttgg
    11461 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11521 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11581 tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
    11641 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11701 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11761 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
    11821 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11881 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11941 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gcgtctgtgt
    12001 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    12061 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12121 ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12181 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgaactgga atggtgagac
    12241 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12301 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12361 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12421 gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12481 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12541 tactgcgtcg gtcattgctc aaggtttcaa ctcatatgta gctgaatggt ctccatacca
    12601 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12661 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12721 ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc aacttggctt
    12781 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12841 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12901 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12961 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    13021 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    13081 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13141 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13201 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13261 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13321 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
    13381 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13441 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13501 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13561 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13621 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13681 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13741 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13801 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
    13861 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13921 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13981 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    14041 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    14101 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14161 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14221 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14281 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14341 gctgctaagt tgacctactt tggactccac agtcttcaac accgtggtca ggagggggca
    14401 ggaatcctct ccaacgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14461 gaagttttca gaaatccatc taatttggat aaattgacag gagctggtgc gattgggcat
    14521 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
    14581 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
    14641 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14701 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14761 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14821 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14881 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    14941 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    15001 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    15061 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15121 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15181 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15241 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15301 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15361 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15421 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15481 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15541 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15601 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15661 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15721 acagattctc cattaaagaa aaggaaaaaa taaatgacaa ataaaaatgc atatgcccag
    15781 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15841 cgtacggaga gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgatctt
    15901 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15961 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    16021 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    16081 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16141 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16201 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16261 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16321 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16381 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16441 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16501 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16561 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16621 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16681 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16741 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16801 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16861 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16921 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    16981 aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt ggaccaacct
    17041 tattgtcggc ttatgaaggt cggattgtca atattcatcc agcctacttg ccagaatttc
    17101 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17161 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17221 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17281 tgtatctgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17341 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17401 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17461 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17521 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17581 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17641 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17701 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17761 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17821 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17881 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17941 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    18001 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    18061 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18121 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18181 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18241 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18301 tatcgatatt ggtgggccat ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18361 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18421 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18481 tgacgccttg attgcaaaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18541 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18601 ggacttttac cagaaagctt tgcctacaga ttactccatt gcttcagcca aacagctcaa
    18661 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18721 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18781 tcaagctgat gacatcgaga ctgcttggga atacgcttat gagtctgacc cagtgtctat
    18841 ctttggtgga attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18901 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    18961 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    19021 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    19081 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    19141 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggcattat
    19201 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19261 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    19321 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19381 catccagccc ggtggctcag tccgtgacca agaatctatc gaagccgctg acaagtatgg
    19441 cttgaccatg gtcttcacag gagtgagaca ttttagacat taagaagata aaagggaaga
    19501 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19561 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19621 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19681 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    19741 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    19801 ggacctttat cggcccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    19861 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    19921 ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19981 attttgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    20041 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    20101 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20161 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20221 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20281 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20341 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20401 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc atcgagttca
    20461 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20521 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    20581 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    20641 ttgagttgcc agtcaaaacc gatggtgaca tcattaccta ctatgcaggg gctaagtttg
    20701 cggaaaatag cagagcgctg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20761 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20821 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20881 acgcgacgca gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20941 tgttctggtc agggggaaac tttgagacct taggctcaaa gtttaggaat gaaaccgaag
    21001 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    21061 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatggagc aattaccgcc
    21121 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21181 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21241 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21301 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21361 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21421 aagaagcccg tagccgtggc atcaagatca tcatcgcagg tgctggtggc gcagcccatt
    21481 tgccaggtat ggtcgctgct aaaacaatcc ttccagtcat tggtgtgcca gtcaactctc
    21541 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21601 ttgcgaccat ggctatcggt gaagcaggtg cgacaaatgc ggccctcttc gctctccgtc
    21661 tcctctcagt agaggatcag tctatcgcga cagcattggc agatttcgca gaagaacaag
    21721 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21781 ggtcaactgg gtcagatgat ggccatttct gctatctaca tggggcacaa ggttatcgcg
    21841 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21901 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    21961 gaaaatgtcg acgctgacgg tttggatgtc gttatcaagg atggacaact ccctcaagga
    22021 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    22081 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22141 gacttgtcga aaaactatgt ccttaagatc gcaacaggtg gttatgatgg acacgggcaa
    22201 aatgtcattc gttcagcaga cgatttggaa gaagcctatg cattagccga ctcagcagct
    22261 tgtgtcttgg aagaatttgt caattttgac cttgagattt ctgtcatcgt gtcaggaaat
    22321 gggaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22381 aagaccatcg taccagcccg tatttctgaa agtctagcag acaaggctaa agctatggca
    22441 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgaca
    22501 gctgatgaca tcattgtcaa tgagattgct ccacgaccac acaactcagg ccactactct
    22561 attgaagcct gtgacttttc acaatttgac acgcatatat taggtgttct gggagcacca
    22621 ttgccagcca tcaaactaca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22681 gaggccgctg aaaaatatgt cacagaaaat ccaagcaccc acctccacat gtatggtaaa
    22741 atagaagcaa agcataatcg taagatggga catgtgactt tgtttagtga tgtaccggat
    22801 agtgtggaag agtttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    22861 gttaatgcat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgctagt
    22921 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    22981 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    23041 tctgtgttta ttggaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    23101 tcccaacagc ttaagaagaa aggaaagatt aacacatgat caaccgttac tctcgccctg
    23161 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    23221 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    23281 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    23341 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    23401 actatgggtt aacttctacc gacgtggtgg atactgccta tggttacctc tacaagcagg
    23461 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    23521 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    23581 cttttggtct taaattggca acttggtata gcgaaatgaa acgcaatatc gagcgcttcg
    23641 agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    23701 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    23761 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    23821 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    23881 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    23941 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    24001 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    24061 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    24121 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    24181 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    24241 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    24301 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    24361 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    24421 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    24481 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    24541 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    24601 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    24661 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    24721 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    24781 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    24841 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    24901 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    24961 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    25021 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    25081 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    25141 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    25201 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    25261 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    25321 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    25381 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    25441 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    25501 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    25561 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    25621 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    25681 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    25741 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    25801 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    25861 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    25921 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    25981 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    26041 gttttacctg caaagaagtc catgtattta ccgataaggg cttttacaaa gttcatcgct
    26101 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    26161 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    26221 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    26281 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    26341 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    26401 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    26461 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    26521 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttcttttaga
    26581 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    26641 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    26701 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    26761 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    26821 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    26881 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    26941 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    27001 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    27061 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    27121 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    27181 ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    27241 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    27301 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    27361 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    27421 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    27481 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    27541 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    27601 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    27661 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    27721 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    27781 tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga gaaatattta
    27841 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    27901 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    27961 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    28021 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    28081 gtttgagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    28141 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    28201 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    28261 tgaggggaat cagaaactgt atggatggtc ggttggtttt ctgtagtagt agtaactcca
    28321 tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc tgctcctaca
    28381 gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa acctcctgat
    28441 tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt tcttatatta
    28501 acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata taaaatttaa
    28561 gcttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata atttttggtt
    28621 ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta agcgctacct
    28681 ttttggtgtg gtataataag catagaaaaa gcccgagcga ttaggctcag gctttcttct
    28741 tagtgatcac ggtcacatga gatgaattta atcttgtagt aatcagatcg tttgtaagtt
    28801 tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt ttgtaggaca
    28861 gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt tggaaagact
    28921 atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa
    28981 cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat atattgttct
    29041 gggatgtagg atgtatggta gatataaacg acaccgtttg attcgcggat acgttcaatc
    29101 ttgtagtaga attgatcgcc gcgtagaccc aatttttcca ggtaaacaag cttgtttccg
    29161 cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc aatatctgaa
    29221 aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg
    29281 acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat agagctgaca
    29341 tcgtacattg aaatgagttc tgcttcagta taaaatttat ctccactgct aaactgccca
    29401 gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat tgccatattt
    29461 ttacctctat tttccttctc catagaaaat tttaccataa aagcgaaaaa aatagtagtc
    29521 ttttgaataa aaaattagaa taatagtttg aaaaattaag ctatataggg attgatcata
    29581 ttttataaat gtattctata caaaattatt ttaggtccta tattccaaat ttaaagagcg
    29641 tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata gtaaaaatgc
    29701 agtaaatatc ccgacaattt ctattgacag ttcaaacaga ttggtttata attaatataa
    29761 caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac gatttgagat
    29821 acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg ccattcatta
    29881 ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg ctcttggttt
    29941 taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag gtgagtttca
    30001 ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt tgggtctcta
    30061 cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg gcttaccagc
    30121 ttggctcttg accaagaaca tgcgaattcg ctcatctgac ccagcatata tcgaggcagt
    30181 tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg acaatggtgg
    30241 caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag ataaggctta
    30301 cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc tctttacatc
    30361 agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg acctctttgt
    30421 aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg aattctttga
    30481 tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt ggttcaatcg
    30541 ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag ttcgagaggt
    30601 tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact ttggtttcat
    30661 gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt atgattacga
    30721 tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca agaagatgat
    30781 ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga gtatggagtt
    30841 ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata gcttgtcaag
    30901 tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt atggctacct
    30961 actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta tcattgatgg
    31021 tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat atcagacaga
    31081 gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt tagatatctt
    31141 gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata cgcaacgtaa
    31201 gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga aacactatcc
    31261 actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc aaggacaacc
    31321 agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc tagacttgtc
    31381 tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt tttggaacgt
    31441 tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg ccaaccgcat
    31501 cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc gtaaacctac
    31561 actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat tgatggacgt
    31621 ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc acgcattatg
    31681 gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa acttgcgaca
    31741 ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa tattcttgct
    31801 ggcaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg cttccttggt
    31861 ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc tcaaacacca
    31921 gaaactcgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga agacttccac
    31981 aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga tccaatttca
    32041 gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt tatgatacaa
    32101 tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga tgagttgacg
    32161 atcgtttcat ctgcaggttc ccctgtattt gctggtttca ttactggttt aatcatggga
    32221 gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct tggggttggt
    32281 accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc gacagccttc
    32341 tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt accagtagca
    32401 gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt cgctcaccgt
    32461 gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta cttgcttggt
    32521 gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc ttttggtggt
    32581 gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc agatggcttg
    32641 acacttgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg ttaccttcca
    32701 gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat gttgactgtt
    32761 ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg tactcttcct
    32821 gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc tatgattggt
    32881 atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca aaaagtagct
    32941 gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga attctaatta
    33001 caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta ctttccaatt
    33061 aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct tgcctcagtt
    33121 gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag ttcatactca
    33181 attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc ttgccatgga
    33241 agaaaaagat ggtgtaggtt caaaagacgc cgttaacggt atcaagacag gtttgatggg
    33301 accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta tcatggggtc
    33361 agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt ggattgcagt
    33421 tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca aagaaggggt
    33481 taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg catctgtact
    33541 tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa tttcttacaa
    33601 gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa tcttcccacg
    33661 tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaga aaggtatgaa
    33721 ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg cccttggtca
    33781 ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga gccatggtcg
    33841 cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag acaacattta
    33901 cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat ttgaagctgt
    33961 tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga caccttgtaa
    34021 tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag ggatgaatct
    34081 tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg actacaagag
    34141 ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg atgatgacga
    34201 agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct tgccgtaggt
    34261 atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt tgagctgact
    34321 tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg ttagagcatt
    34441 ttatatagaa tatacatggg aatgtagctt actcccattc ccatatttaa tagaaaaaga
    34501 ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca gaaatcacta
    34561 cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt tatcaagcaa
    34621 aacgtgaaga aattgcagcc ttcctacaag aaatcgctga taaacatgac tatattaagg
    34681 ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta ccttatttta
    34741 aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca gatatcgttg
    34801 ccaatccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct tttgctcgta
    34861 gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg gtggatgagc
    34921 tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa gctcacggtg
    34981 atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga tttgccatga
    35041 cttctagctt tacgtctatg atgttgacag ctctcttggt ctttgatcct acagaatttg
    35101 ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt ttagacaagg
    35161 cagaagatgt caaagagctt gttgatttag actttaaccg tgtcatctat ctaggcgctg
    35221 gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta actgctggtc
    35281 aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa tctcttatca
    35341 acgacaatac agttgttttg gtctttggta caacgacaga ctacactcgt aagtatgact
    35401 tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg cttttgagtg
    35461 atcaagcttt tggtcttgaa aatgtcaaag aagtggccct tggttgtggc ggtgtcttga
    35521 atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc ctattgactt
    35581 cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta aaccgtgtag
    35641 tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa ttcttgacaa
    35701 gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta tggtttgttt
    35761 gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg tgtatttgga
    35821 aatgttgagg gcgaggatgt cttggcctat cgatttgaga cagacggtgg ctaccaactt
    35881 gaggttatga cttatggcgc gaccatcttg cgctatgtcg cacctgacaa ggctggaaat
    35941 tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa tagtcccaag
    36001 catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt tgagctcaat
    36061 ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag tggttcaact
    36121 ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt gactctctac
    36181 acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg gatcagttat
    36241 cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga tcaggatacg
    36301 ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac gcagacgatt
    36361 gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc tgacggtgtt
    36421 cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acgtctacaa tggtaccttg
    36481 ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg tttggatcat
    36541 ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca aaattcaggt
    36601 cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc aaactttgtg
    36661 gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat tgctcttgaa
    36721 gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat tcttaaggct
    36781 ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa aagctggtca
    36841 aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt gatactatgc
    36901 gttttgttat gaaatgattt actttatctt atcctgaaat ggtgttattt ttgagttatc
    36961 tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat tacaacgaga
    37021 aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca gagacagttt
    37081 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    37141 tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc ttggtacagc
    37201 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    37261 ttctcttacc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    37321 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    37381 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    37441 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    37501 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttcag
    37561 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    37621 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    37681 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    37741 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    37801 ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac tcagatggca
    37861 tcgtgacctg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    37921 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    37981 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    38041 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    38101 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    38161 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    38221 ctgaagctca aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa
    38281 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag
    38341 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat
    38401 gtactgaccc c
//
LOCUS       DAVBOU010000016        37863 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBOU010000016 DAVBOU010000000
VERSION     DAVBOU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.016"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..381
                     /locus_tag="VQ879_000891"
     CDS             <1..381
                     /locus_tag="VQ879_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3143064.1"
                     /translation="NLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHR
                     FLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIIDYIDY
                     YNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(426..1067)
                     /gene="plsY"
                     /locus_tag="VQ879_000892"
     CDS             complement(426..1067)
                     /gene="plsY"
                     /locus_tag="VQ879_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3143065.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1203..3146
                     /gene="parE"
                     /locus_tag="VQ879_000893"
     CDS             1203..3146
                     /gene="parE"
                     /locus_tag="VQ879_000893"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3143066.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3566..6037
                     /gene="parC"
                     /locus_tag="VQ879_000894"
     CDS             3566..6037
                     /gene="parC"
                     /locus_tag="VQ879_000894"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3143067.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEITKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6169..7191
                     /locus_tag="VQ879_000895"
     CDS             6169..7191
                     /locus_tag="VQ879_000895"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3143068.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7247..7951
                     /locus_tag="VQ879_000896"
     CDS             7247..7951
                     /locus_tag="VQ879_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3143069.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8016..8705
                     /locus_tag="VQ879_000897"
     CDS             8016..8705
                     /locus_tag="VQ879_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3143070.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8702..9625
                     /locus_tag="VQ879_000898"
     CDS             8702..9625
                     /locus_tag="VQ879_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3143071.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9640..10284
                     /gene="pcp"
                     /locus_tag="VQ879_000899"
     CDS             9640..10284
                     /gene="pcp"
                     /locus_tag="VQ879_000899"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3143072.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10452..10682
                     /locus_tag="VQ879_000900"
     CDS             10452..10682
                     /locus_tag="VQ879_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3143073.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10732..10812
                     /locus_tag="VQ879_000901"
     tRNA            10732..10812
                     /locus_tag="VQ879_000901"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10766..10768,aa:Tyr,seq:gta)
     gene            10822..10893
                     /locus_tag="VQ879_000902"
     tRNA            10822..10893
                     /locus_tag="VQ879_000902"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10854..10856,aa:Gln,seq:ttg)
     gene            11055..12257
                     /gene="rpsA"
                     /locus_tag="VQ879_000903"
     CDS             11055..12257
                     /gene="rpsA"
                     /locus_tag="VQ879_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3143074.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12343..12840
                     /locus_tag="VQ879_000904"
     CDS             12343..12840
                     /locus_tag="VQ879_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3143075.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12840..14495
                     /gene="dnaX"
                     /locus_tag="VQ879_000905"
     CDS             12840..14495
                     /gene="dnaX"
                     /locus_tag="VQ879_000905"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3143076.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14523..14717
                     /locus_tag="VQ879_000906"
     CDS             14523..14717
                     /locus_tag="VQ879_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3143077.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14867..15637
                     /gene="sufC"
                     /locus_tag="VQ879_000907"
     CDS             14867..15637
                     /gene="sufC"
                     /locus_tag="VQ879_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3143078.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15665..16927
                     /gene="sufD"
                     /locus_tag="VQ879_000908"
     CDS             15665..16927
                     /gene="sufD"
                     /locus_tag="VQ879_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3143079.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16938..18164
                     /locus_tag="VQ879_000909"
     CDS             16938..18164
                     /locus_tag="VQ879_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3143080.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18151..18591
                     /locus_tag="VQ879_000910"
     CDS             18151..18591
                     /locus_tag="VQ879_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3143081.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18645..20057
                     /gene="sufB"
                     /locus_tag="VQ879_000911"
     CDS             18645..20057
                     /gene="sufB"
                     /locus_tag="VQ879_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3143082.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20256..21497)
                     /locus_tag="VQ879_000912"
     CDS             complement(20256..21497)
                     /locus_tag="VQ879_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3143083.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21600..22709
                     /locus_tag="VQ879_000913"
     CDS             21600..22709
                     /locus_tag="VQ879_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3143084.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23355..23702
                     /gene="ssrA"
                     /locus_tag="VQ879_000914"
     tmRNA           23355..23702
                     /gene="ssrA"
                     /locus_tag="VQ879_000914"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23885..23972)
                     /locus_tag="VQ879_000915"
     tRNA            complement(23885..23972)
                     /locus_tag="VQ879_000915"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23936..23938),aa:Ser,seq:gga)
     gene            24134..24874
                     /locus_tag="VQ879_000916"
     CDS             24134..24874
                     /locus_tag="VQ879_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3143085.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24871..25782
                     /gene="pfkB"
                     /locus_tag="VQ879_000917"
     CDS             24871..25782
                     /gene="pfkB"
                     /locus_tag="VQ879_000917"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3143086.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25779..27731
                     /locus_tag="VQ879_000918"
     CDS             25779..27731
                     /locus_tag="VQ879_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3143087.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27895..30120
                     /locus_tag="VQ879_000919"
     CDS             27895..30120
                     /locus_tag="VQ879_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3143088.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30273..30701)
                     /locus_tag="VQ879_000920"
     CDS             complement(30273..30701)
                     /locus_tag="VQ879_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143089.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30839..31981
                     /locus_tag="VQ879_000921"
     CDS             30839..31981
                     /locus_tag="VQ879_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3143090.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31990..33204
                     /gene="thiI"
                     /locus_tag="VQ879_000922"
     CDS             31990..33204
                     /gene="thiI"
                     /locus_tag="VQ879_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3143091.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33339..34163
                     /locus_tag="VQ879_000923"
     CDS             33339..34163
                     /locus_tag="VQ879_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3143092.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34176..35342
                     /locus_tag="VQ879_000924"
     CDS             34176..35342
                     /locus_tag="VQ879_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3143093.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            35850..37343
                     /locus_tag="VQ879_000925"
     CDS             35850..37343
                     /locus_tag="VQ879_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3143094.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37356..>37863
                     /locus_tag="VQ879_000926"
     CDS             37356..>37863
                     /locus_tag="VQ879_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3143095.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT        11455 a         6886 c         8388 g        11134 t
ORIGIN      
        1 aatctttcaa cttcacccaa cttagaacaa gtacaaacaa tgttggaaca ggcattcaca
       61 gagaagcact acgagaatac gattctccat agtgaccaag gctggcaata tcaacacgat
      121 tcttatcatc ggttcttaga gagtaaggga attcaagcat ccatgtcacg caagggaaac
      181 agccaagaca atggtatgat ggagtccttc tttgggattc tgaaatcgga aatgttttac
      241 ggttatgaga agtcgtttca gtcgcttaag caattggaac aagccattat agactatatt
      301 gattactaca acaacaagag aattaaggta aaactaaaag gacttagccc tgtgcaatac
      361 agaactaaat ccttcggata aattaattgt ctaacttttg gggggcagtt cacagaactg
      421 gcattttatt ttttaggatc ttgatgggtt aggttcaatc cccaagggac caaattttca
      481 gttttatttt tgatacgagc tatattgtcc ttatgacgaa tgataatcaa actagcaagt
      541 gctaagataa tagcgatgaa gagagagtca tagttactca ggataaaacc aaaaagtgga
      601 aagagcagaa ccccgataac agccgcgatc gatgctgtga cactagacag tgaaatcata
      661 ctgccaagat agagagctcc aaagaagata atcgcaaggt agagacagaa gataggcgca
      721 aatccgaaaa ttactccagc actggttgcg acagccttac cacctttaaa tcctgcaaag
      781 atagggaagg tatggccgat aacagccaaa agtccaaaga tgagaggaga aacgccttgt
      841 agatgaaaaa taatcggaag cagcgttgct agggttcctt tgaaaaagtc aatcacaaag
      901 gttgccatac cagctttctt acctaaaatg cggaaggtat tggtcgttcc agtgttacca
      961 gaaccatgct cgcgtagatt gatttgaaag aatacttgtc caatccagag accagatgga
     1021 atcgaaccca gcagataggc taggattaat aaaactattg taatcatact cctattatat
     1081 catgaattgg gaaagaaaag cagagaatct ctgctaaaat tgtcacatcg gagaaagaaa
     1141 aattttgcaa aatccttgga aaacctgtag aatagtaaag atgaacgaat aggaggttcc
     1201 ttgtgtcaaa aaaggaaatc aatattaaca attataatga tgatgctatt caggtgctag
     1261 aagggttgga tgcggtccga aaacgtccag ggatgtatat tggatcgacc gatggcgctg
     1321 gtcttcatca cctagtttgg gaaatcgttg ataatgcagt cgatgaagcc ttgtctgggt
     1381 ttggtgatcg tatcgatgta accatcaata aagacggtag tctaacggtt caagaccatg
     1441 gacgtgggat gccgacaggt atgcacgcta tgggaattcc aactgttgag gttatcttta
     1501 ccattcttca tgccggaggg aaattcggtc aaggtggcta taagacatca ggtggacttc
     1561 acggagtggg ttcttccgtt gttaacgccc tttctagctg gttagaagtt gaaattaccc
     1621 gtgatggcgc agtttacaag caacgtttcg aaaatggtgg aaaacctgtc acgactttga
     1681 agaaaatcgg tacagcaccc aagtctaaaa caggcaccaa agttactttt atgcctgacg
     1741 cgactatatt ttctacgaca gatttcaagt acaataccat ttcagagcgc cttaatgaat
     1801 cagcctttct cttgaaaaat gtgaccttgt ctttaacgga caagcgaaca gatgaagcga
     1861 ttgagttcca ctatgagaat ggagtacaag attttgtttc ttatctcaac gaagataagg
     1921 aaatcttgac gccagttctt tactttgaag gggaagacaa tggttttcaa gtggaagtag
     1981 ccctccagta caatgacgga ttctcagata acattctatc ctttgtcaat aacgttcgca
     2041 ccaaggacgg tggaacgcac gagacaggac tcaagtctgc cattaccaag gtcatgaatg
     2101 actatgcacg taaaacaggt cttctcaagg aaaaagataa aaaccttgaa ggttcagact
     2161 atcgtgaggg actagcggcc gttctttcta tcttagttcc tgaagaacac ttgcagtttg
     2221 aaggacagac caaggataaa ctaggaagcc ccctagctcg cccagttgtg gatggaatag
     2281 tggctgataa gttgaccttt ttccttatgg aaaatgggga attagcttct aacctcatcc
     2341 gcaaggctat caaggcccgt gatgctcgtg aagcagcacg taaggcgcgt gatgagagcc
     2401 gaaatgggaa gaaaaacaag aaagataagg gcttgttgtc tgggaaattg accccagccc
     2461 aatctaagaa tcctgctaag aatgaactct atctagttga gggggactct gccggtggtt
     2521 ctgccaaaca aggtcgtgac cgcaagttcc aggctattct acctcttcgt ggtaaggtta
     2581 tcaatacagc caaggccaag atggcggata tcctcaaaaa tgaagagatc aataccatga
     2641 tttataccat tggtgcgggt gttggagcag acttctctat tgaagatgcc aactatgata
     2701 agatcattat catgaccgat gcggataccg acggtgccca tatccagacc ttgctcttga
     2761 catttttcta ccgttacatg cgtccgctag tcgaggcagg tcatgtctat attgccctcc
     2821 cacctcttta caagatgtcc aaaggtaaag gaaagaaaga agaagtggcc tacgcttgga
     2881 cggacggaga actagaagaa ctccgtaaac agttcggtaa aggcgctacc ctccaacgat
     2941 acaaaggact tggtgagatg aatgcggacc agctctggga aacaaccatg aacccagaaa
     3001 cacgtaccct catccgtgtc acaattgaag atttagcgcg cgccgaacgc cgcgtcaatg
     3061 ttctcatggg agataaggta gaaccacgcc gtaaatggat tgaagataat gtcaagttta
     3121 cgctagaaga agcgacagtg ttttaatgaa agaaaataat atgttagtaa actggaaatt
     3181 agagtcggat gtgaatgact atgtgaaaaa gcagtttgaa aatcttggtt tgaaaaaatt
     3241 gcaggattat taatgaagaa tctgctatga gtgcttatct caaagaggcg cttaagggag
     3301 cggctaagac acaaactaag actaattttg gaaaaccaga ttttcatatt gaaaaataca
     3361 aacaggatag tttggttact tatcgtaact gaacacggga ggaattcccg taaaatatct
     3421 tttactgcat aaaaacctac tctacattct ttgaaaggag ttgaacacgc cctagatact
     3481 gtgtgaaaaa gataaattct cttgtgagtt tgcttacttc aagaattttc tattttcact
     3541 tggtatttta tgggctttgt atcttatgtc taacattcaa aacatgtccc tggaggacat
     3601 catgggagag cgctttggtc gctactccaa gtacattatt caagaccggg ctttgccaga
     3661 tattcgtgat gggttgaagc cggttcagcg ccgtattctt tattctatga ataaggatag
     3721 caatactttt gacaagagct accgtaagtc ggccaagtca gtcgggaaca tcatggggaa
     3781 tttccaccca cacggggatt cttctatcta tgatgccatg gttcgtatgt cacagaactg
     3841 gaaaaatcgt gagattctag ttgaaatgca cggtaataac ggttctatgg acggagatcc
     3901 tcctgcggct atgcgttata ctgaggcacg tttgtctgaa attgcaggtt accttcttca
     3961 ggatatcgag aaaaatacag ttccttttgc atggaacttt gacgatacgg agaaagaacc
     4021 aacggtcttg ccagcagcct ttccaaacct cttggtcaat ggttcgactg ggatttcggc
     4081 tggttatgcc acagacattc ctccccataa tttagctgag gtcatagatg ctgcagttta
     4141 catgattgac cacccaactg caaagattga taaactcatg gaattcttgc ctggaccaga
     4201 cttccctaca ggggctatta ttcagggtcg tgatgaaatc aagaaagctt atgagactgg
     4261 gaaagggcgc gtggttgttc gttccaagac tgaaattgaa aagctaaaag gtggtaagga
     4321 acaaatcgtt attactgaga ttccttatga aatcactaag gccaatctag tcaagaaaat
     4381 cgatgatgtt cgtgttaata acaaggtagc tgggattgct gaggttcgtg atgagtctga
     4441 ccgtgatggt cttcgtatcg ctatcgaact taagaaagac gctaatactg agcttgttct
     4501 caactactta tttaagtaca ccgacctaca aatcaactac aactttaata tggtggcgat
     4561 tgacaatttc acacctcgtc aggttgggat tgttccaatc ctgtctagct acatcgctca
     4621 ccgtcgagaa gtgattttgg cgcgttcacg ctttgacaaa gaaaaggctg agaaacgtct
     4681 ccatatcgtc gaaggtttga ttcgtgtgat ttcgattttg gatgaagtca ttgctcttat
     4741 ccgtgcttct gagaataagg cggacgccaa ggaaaacctc aaagttagct atgattttac
     4801 ggaagaacag gctgaggcta tcgtaacttt gcaactgtac cgtttgacca ataccgatgt
     4861 ggttgtcttg caggaagaag aagcagagct tcgtgagaag attgctatgc tggcggctat
     4921 tatcggtgat gaaaggacta tgtacaatct catgaagaaa gaacttcgtg aggtcaagaa
     4981 gaaatttgca actcctcgtt tgagttcttt agaagacact gcgaaagcaa ttgagattga
     5041 tacagctagt cttatcgctg aggaagatac ctacgtcagc gtgaccaagg caggttacat
     5101 caagcgtacc agtccacgtt cctttgcggc ttccaccttg gaagaaattg gcaagcgtga
     5161 tgatgaccgt ttgatttttg ttcaatctgc caagacaacc cagcacctct tgatgttcac
     5221 aagtcttgga aatgtcatct acagaccaat ccatgagttg gcagatattc gttggaagga
     5281 catcggagag catctgagcc aaaccatcac aaactttgaa acgaatgaag aaatccttta
     5341 tgtggaagta ctggatcagt ttgacgatgc gacaacctac tttgcagtga ctcgccttgg
     5401 tcaaatcaaa cgggtagagc gaaaagaatt cactccatgg cggacctata gatctaagtc
     5461 tgtcaagtat gctaagctca aagacgatac agatcagatt gtagcagtgg ctccgattaa
     5521 actagatgat gttgtcttgg ttagtcaaaa tggttatgcc ctgcgtttca atatcgaaga
     5581 ggttccggtt gtcggtgcta aggcagcagg tgtcaaggct atgaatttga aagaagatga
     5641 tgtcctccaa tctggcttta tctgtaatac ttcgtccttc tacctcttga cccagcgtgg
     5701 aagcttgaaa cgtgtttcta ttgaggaaat tctagcaacc agccgtgcca aacgaggatt
     5761 acaagtcttg cgtgagttga aaaacaaacc gcatcgtgtc ttcttggcag gagcagttgc
     5821 agagcaagga tttgttggcg atttcttcag tacggaagtg gatgtgaacg accaaactct
     5881 gcttgtccaa tccaataaag gaacaatcta tgaaagccga ttgcaagact tgaacttgtc
     5941 agaacgcact agcaatggaa gcttcatttc tgacacgatt tcagatgaag aagtttttga
     6001 cgcttatctt caggaagtag ttactgaaga taaataagtg aaatgaagaa tcagttctaa
     6061 gagctggttt ttattggaga aattttctga aaattacaaa atatacttgc tattttagaa
     6121 aaatagtgta gaatataaga aataggtttt tagaataagg agtggaatat gacagtaacg
     6181 attgattggg aaaacctcgg tttttcctat atgaaattac cttatcgcta tcttgctcat
     6241 ttcaaaaatg gacaatggga tcaaggagag cttacagagg atgcaacttt gcatatttca
     6301 gagtcttctc caagtcttca ctatggacaa caagcatttg aaggtttgaa agcttatcgt
     6361 actaaggatg gcagtgttca actgttccgt cctgatgaaa atgctaaacg tctgcaacgt
     6421 acatgtgacc gtctcttgat gccacaagtt ccgacagaca tgtttgtaga agcttgtaaa
     6481 gcagttgtcc gtgcgaatga agaatacgta ccaccatacg gaacaggtgg aaccttatat
     6541 cttcgccctc ttttgattgg tgtcggagat attatcgggg taaaaccggc agaagagtac
     6601 attttcacca tctttgctat gccagttgga aattacttta aaggtggttt ggtcccaacc
     6661 aacttcttga ttcaggatga gtacgaccgt gcagcaccaa atggtacagg tgcggctaag
     6721 gttggtggaa actatgctgc aagtctctta ccaggaaaaa tggccaagtc acgtcatttc
     6781 tcagatgtta tctatctgga cccatcaact catacaaaga ttgaagaagt cggatcagct
     6841 aacttctttg gaattacagc tgataatgaa tttgtaacac cattgagtcc atctatcttg
     6901 ccatctatta ccaagtattc cttgctttat ttggcagaac atcgcttggg attaactcct
     6961 attgagggtg atgttccaat tgataatctt gaccgttttg tagaggcagg tgcctgtggt
     7021 acagcagcgg ttatttctcc aattggaggt attcaacatg gtgatgattt ccatgtattc
     7081 tatagtgaaa cagaagtagg tcctgtgacg cgtaaattat ataatgaatt gacgggtatt
     7141 cagtttggcg atattgaagc gccagaaggt tggattgtaa aagtagatta aaataaacca
     7201 aaggagattt tttatgaaat agaaaaagtg gctcttaaca gcaggagtgg tcctgagcac
     7261 gtcagctatt ttagtggctt gtggaaaaac tgataaagaa gcagatgcac cgacaacatt
     7321 ttcttatgtc tatgcagtag atccagcatc attgggctac agtatagcga ctcgaacatc
     7381 gaggacagac gttattggaa atgttattga tggtttgatg gaaaatgata aatacggcaa
     7441 tgttgctcct tctcaaaaag actatgattt gaacggtaca ggatgggctc caagctatca
     7501 agatccagcg tcttacttga atattatgga tccaaaatct ggttctgcca tgaaacacct
     7561 tggcattacg aaaggaaaag ataaggatgt tgtagctaaa cctggtttgg ataaatataa
     7621 gaaattgtta gaagatgctg tttctgagac cactgaccta gagaagagat atgaaaaata
     7681 tgccaaagct caagcttggt cgacagatag ttcattattg atgccaacag cttcatctgg
     7741 tggttttcca gttgtaagta acgtagtacc attctcaaaa ccatactcac aagttggtat
     7801 taagggggaa ccatatatct ttaaaggaat gaaattgcaa aaagatattg ttacaacaaa
     7861 agaatataac gaggttttta aaaaatggca aaaagaaaaa ttggaatcca atagcaaata
     7921 ccaaaaagaa ctagaaaaat acattaaata aggaatggta ttgatcttga taaaattttt
     7981 aaaatactgt cattttgaat ataaaggagt ttgatatgga gtggattaga ttaataggaa
     8041 tagcaatcat tgttgtgggt tttattttaa aatttgatac aattgcaaca gtagtcttag
     8101 ctggtttggt tacagcttta gtttcaggtg tttctctcgt tgaatttttg gagattttgg
     8161 gaaaagaatt tagcaatcag cgagtgctca cgatttttat ggttaccttg cctcttgtgg
     8221 ggctgtcaga aacctttgga ctcaagcaac gatcaatcga tttgattcga aagattaaag
     8281 gtctgacagt tggaaacttc tatacagttt atttctttat tcgagagtta gctggtttct
     8341 tttcaattcg tctaggagga caccctcagt ttgtcagacc tttggttcaa cctatgggag
     8401 aagcagctgc agagtctcaa ttaggtagaa agttaacaga ggttgaagat gagacaataa
     8461 aagcgcgtgc ggctgcgaat gaaaattttg gaaatttctt tgctcaaaat acgtttgtag
     8521 gtgctggggg agtcctcttg atagggggaa cattagatca gttaggctat gaaagcaatt
     8581 atgcagggat tgcttctaca tctattattg ttgctgttat aacacttatt gtagtgggga
     8641 tttacaatta tttatttgat aaaaaattga tatcaaaaaa gactagggga ggagaacaaa
     8701 aatgacagag ttggcaaagc aactattaga gttgacctat attgtgattg gttgtcaatt
     8761 tctccataca gcctattgta gttataaaga taaaacaaac ccagttcgac ttgggacatc
     8821 tgcattttgg actctattgt ctattacgtt tataggtggt tcctatatgc caaatatgag
     8881 tattggtatt attgtaatcc tattatcgct gttaacattg tttaagcaag tccgtatcgg
     8941 aaccttgcca tccttagatg aaatgaaagc caatattgaa tctaacaggt tgaaaaataa
     9001 aatttttatt ccagttatgc tgatggcaat acttgcgttg gtcttagcgc aaatgattcc
     9061 agaatttagc aagatttcga ttagccttgc cgccttgttt gctacaattt ctgttcttgt
     9121 gattaccaat agtcacccta agagtctgtt atcagaaaat aatcgaatga ctcagcaagt
     9181 ttcaacaagt ggtattgttc ctcaattatt aggggctttg ggggctattt ttactgtagc
     9241 aggtgttggt gatgttatct ctcatctgat tagcggtatt gttccttcag atagtcgctt
     9301 tataggagtt ttggcttatg ttcttggaat ggttctattc acaatgatta tgggaaatgc
     9361 ttttgcagca ttcaccgtta ttacagcagg tgttggagtt ccctttgtat ttgctctggg
     9421 agctaatcca attgtggctg gtgctcttgc catgacagca ggttattgtg ggaccttatt
     9481 gaccccaatg gctgctaatt ttaacgctct accagcagca ttgatggata tgaaagatca
     9541 gaatggcgtt ataaaggctc aagcaggtgt tgctctagta atgattgtta ttcacatatt
     9601 cttaatgtac tttctcgcat tttagtaaag gaaaataaaa tgaaaatatt ggttacaggt
     9661 tttaatcctt ttggaggtga aaagattaat ccagctttgg aggctgtaaa attattacca
     9721 tctgagatta atggggctga agttcgctgg gtagaaattc caacggtttt ttataagtcg
     9781 tcagaagttt tagaggcaga aatattacga tatcaaccag atgctgtact ttgtattgga
     9841 caagcaggcg gcaggaccgg cttaacacct gaacgagtgg ctattaatca agatgatgct
     9901 cgcatacctg ataacgaagg caatcaacca attgatacac cgattcgtat tgatggagca
     9961 tcggcctatt ttagtagttt acctatcaaa gcgatggtac aagctatcaa aaaacaggga
    10021 cttccggcag ttgtatccaa tagtgcagga acctttgttt gcaatcattt gatgtaccaa
    10081 gctctttatt tagtggataa aaaattccct aatatgagag caggtttcat gcatattcca
    10141 tatatgatgg aacaagtagt aaataagccg aatactgcag gaatgagtct atgtgatatt
    10201 gtaagaggca tagaggtagc tattgaagct attgtagact acaaagataa ggatttgcag
    10261 ttagtaggcg gtgagactca ctgataacct aaaaaggata gtcaattatg cttgtttact
    10321 aactattaac tatgctaaat caattgaggt tgtttacata aaactctata tcagagaagc
    10381 ctgatataga gttttttctt gctagtttta ggattttctt gtaaaataga aaaagtgaag
    10441 agaggtatga aatgagcaag aaagataaaa aaatcgaaat tcaagtagcg gatgccaaag
    10501 ttaatgttgg taaagacagt tttgaaggtt atacattgac tatcggtaaa aaagttatcg
    10561 gagaaattgc cgaattagac ggacaatttg ccattataaa gaatgggaat gtcgatagtt
    10621 tttataaaaa attggaaaaa gctgtggaaa ttttgattga aaattataat ttagcaaaat
    10681 aagtcttgtt tttttgaaat tttcatgata taatagtcca tgttgattgt aggagagata
    10741 gcgaagaggc taaacgcggc ggactgtaaa tccgctcctt cgggttcggg ggttcgaatc
    10801 cctctctctc catttcatta atggggtata gccaagcggt aaggcaaggg actttgactc
    10861 cctcatgcgt tggttcgaat ccagctaccc cagttcttag gtaataatca agataaaaag
    10921 caaaatatct tagggtattt tatttttata attgaaagac gtgaatgata tgaacatgtc
    10981 cttgcgggtg cttaggaaaa aaattataag tatgtcaagt ttaagaaaaa cttgattgtt
    11041 ggaggatttt ttagatgaac gaatttgaag atttgctaaa tagcgttagt caagttgaga
    11101 ctggtgatgt tgttagtgct gaagtattga cagttgatgc gactcaagct aacgttgcaa
    11161 tctctggaac tggtgttgaa ggtgtcttga ctcttcgcga attgacaaac gatcgtgatg
    11221 cagatatcaa tgactttgtt aaagtaggag aagtattgga tgttcttgta cttcgtcaag
    11281 tagttggtaa agatactgat acagttacat accttgtatc taaaaaacgc cttgaagctc
    11341 gcaaagcatg ggacaaactt gttggtcgcg aagaagaagt tgttactgtt aaaggaacgc
    11401 gtgccgttaa aggtggactt tcagtagaat ttgaaggtgt tcgtggattt atcccagctt
    11461 caatgttgga tactcgtttc gtacgtaacg ctgagcgttt tgtaggtcaa gaatttgata
    11521 ctaaaatcaa agaagttaac gctaaagaaa accgcttcat cctttcacgt cgtgaagttg
    11581 ttgaagcagc tactgcagca gctcgcgctg aagtattcgg taaattggct gttggtgatg
    11641 ttgtaactgg taaagttgct cgtatcacaa gcttcggcgc tttcatcgac cttggtggtg
    11701 ttgacggatt ggttcacttg actgaattgt cacatgaacg taacgtatca ccaaaatcag
    11761 ttgtaactgt tggtgaagaa attgaagtga aaatccttga tcttaacgaa gaagaaggac
    11821 gtgtatcact ttcacttaaa gcaacagtac caggaccatg ggatggcgtt gagcaaaaat
    11881 tggctaaagg tgatgtagta gaaggaacag ttaaacgttt gactgacttc ggtgcatttg
    11941 ttgaagtatt gccaggtatc gatggacttg ttcacgtatc acaaatttca cacaagcgga
    12001 ttgaaaatcc aaaagaagct cttaaagttg gtcaagaagt tcaagttaaa gttcttgaag
    12061 ttaacgcaga tgcagaacgc gtgtcacttt ctattaaagc tcttgaagaa cgtccagccc
    12121 aagaagaagg acaaaaagaa gaaaaacgtg ctgctcgtcc acgtcgtcca agacgtcaag
    12181 aaaagcgtga tttcgaactt ccagaaacac aaacaggatt ttcaatggct gatttgtttg
    12241 gtgatatcga actttaatca aattgaaaat tcacaaaatc ctttgtttac taaacaaggg
    12301 atttttcttt tgtctctgct ccttttttga tataatagtt ctatgttaaa atcagaaaaa
    12361 caatcacgtt atcaaatgtt aaatgaagaa ttgtccttcc tattggaagg cgaaaccaat
    12421 gttttggcta atctttccaa cgccagtgct cttataaaat cacgttttcc taataccgta
    12481 tttgcaggct tttatttgtt cgatggaaag gaattggttt taggtccctt ccaaggaggt
    12541 gtttcctgca tccgtattgc actaggcaag ggtgtttgtg gtgaggcagc tcactttcag
    12601 gaaactgtta ttgttggaga tgtgacgacc tatctcaact atatttcttg tgatagtcta
    12661 gctaaaagtg aaattgtggt gccgatgatg aagaatggtc agttacttgg agttctggat
    12721 ctggattctt cagagattga ggattacgat gctatggatc gagattattt ggaacaattt
    12781 gtcgctattt tgcttgaaaa gacaacatgg gactttacga tgtttgagga aaaatcttaa
    12841 tgtatcaagc actttatcga aaatatagaa gtcaaaactt ctcccagtta gttggtcaag
    12901 aagttgtggc taagactctt aaacaagcgg tggagcaaga gaaaataagt cacgcttatc
    12961 ttttttctgg tcctcgtgga acgggaaaaa ccagtgttgc taaaatcttt gccaaggcta
    13021 tgaactgtcc caatcaagtg ggtggcgaac cttgcaataa ctgctatatt tgtcaagcag
    13081 tgacggacgg tagtttagaa gatgtcattg aaatggatgc agcttctaat aatggggtag
    13141 atgaaattcg cgaaattcgt gataaatcta cctatgcgcc tagccttgct cgttataagg
    13201 tttatatcat agatgaggtt cacatgctgt ctacaggggc ttttaatgcc ctcctaaaga
    13261 cgctggaaga accaacacag aatgtagtct ttattttggc cactactgaa ttgcacaaga
    13321 ttcctgctac tattctatcc cgtgtgcaac gttttgagtt taaatcaatt aagacacagg
    13381 atattaagga acatattcac tatatcttag aaaaagaaaa tatcagttct gaaccagagg
    13441 ctgtggaaat cattgccaga cgggcggaag gtggaatgcg ggacgccttg tctattttgg
    13501 atcaagccct gagtttgaca cagggaaatg agctgacgac tgctatctct gaagaaatta
    13561 ctggcaccat tagcctatca gccttggatg attatgtggc ggccttgtct caacaggatg
    13621 ttcccaaagc tttgtcttgc ttgaatcttc tttttgacaa tggtaagagc atgactcgtt
    13681 ttgtgaccga tcttttgcac tatttaagag acttgttaat tgttcaaaca gggggagaaa
    13741 atactcatca tagttcagtc tttgtagaaa atttggcact tcctcaaaaa aatctgtttg
    13801 aaatgattcg cttagcaaca gtgaatttag cagatattaa gtctagtttg cagcccaaga
    13861 tttatgctga aatgatgacc gtccgtttgg cggaaatcaa gcccgaacca gctctatcag
    13921 gagcggttga aaatgaaatt gctacgctga gacaggaagt tgcccgtctc aaacaagagc
    13981 tttctaatgc aggtgcggtt cctaaacaag ttgcaccagc tcctagtcga ccagctacgg
    14041 gcaaaacagt ctatcgtgtc gatcgcaata aagtgcaatc tatcttacaa gaggccgtcg
    14101 aaaatcctga tttagcacgt caaaatctaa ttcgtttgca gaatgcctgg ggagaggtaa
    14161 ttgaaagtct aggtgggccg gacaaggctc tgctagttgg ttctcaaccg gttgctgcca
    14221 atgaacacca tgctattctt gcttttgagt ctaacttcaa tgctggtcaa actatgaaac
    14281 gagacaatct caataccatg tttggtaata tcctcagtca ggcggcaggt ttttcacctg
    14341 agattttagc tatttccatg gaggaatgga aagaagttcg cgcagccttt tcagccaaag
    14401 ccaaatcttc tcaaactgaa aaagaagtag aagaaagcct gattccagaa ggatttgaat
    14461 ttttggctga taaagtgaag gtagaggaag actaaagaaa gatttcatga tacaataagt
    14521 ttatgaataa acaacaattt attattatgg cgctatttac agctgctgag acctattttt
    14581 tcaatgaagc ctggatgact ggccgctata ttatggcagc cttttgggca attttactct
    14641 ttagaaattt ccgagtcagt tatgtgatgg gtaaaattgt tgatgtcatc gatcagcatt
    14701 ttaataggaa agactagccc tcagcttcca gacaaaatca aagcctttta ggcttttttt
    14761 tgttatacta gaaaagtata tttatagaat ttttgctcta tttctgggga aatcagacgt
    14821 ttttctagta agtactgtaa aagttttgaa aaagaaagga actatcatgt cagtaataga
    14881 gatcaaagat cttcacgttg agattgaagg aaaagaaatt ttaaaagggg ttaacctgac
    14941 cctgaaaaca ggagaaattg ccgctatcat gggaccaaat ggtacaggta aatcgactct
    15001 ttctgccgct atcatgggaa atccaaacta tgaagtaact aaaggtgaag ttttgtttga
    15061 tggcgtaaac atccttgagt tggaagtgga tgagcgtgcg cgtatgggac ttttccttgc
    15121 tatgcaatac ccatcagaaa tccctggaat taccaatgct gagtttcttc gtgccgctat
    15181 gaatgcgggt aaagaagatg atgagaagat ttcagttcgt gagtttatta ctaagctaga
    15241 tgaaaaaatg gaattgctca acatgaaaga agaaatggca gagcgttacc tcaacgaagg
    15301 cttctctggt ggtgagaaaa aacgcaatga aattcttcaa cttttgatgt tggagccaac
    15361 atttgctctt ttggacgaga ttgactcagg tcttgatatt gacgctctta aagttgtgtc
    15421 taaaggtgtc aatgccatgc gtggtgaagg ttttggtgct atgatcatca ctcactacca
    15481 acgtcttttg aactatatca cacctgatgt ggtacacgtg atgatggaag gtcgtgttgt
    15541 cctttctggt ggtccagaat tggctgcgcg tttggaacgt gaaggatacg caaaattagc
    15601 tgaagaactt ggctacgact acaaggaaga attgtaattt cctcgtatct tttaggagaa
    15661 gtaaatgact agagaaaata ttaaactttt ttcagaaatg cacgctgaac caagctggtt
    15721 ggctgatctc cgtcaaaaag cttttgacaa gattgagact ttggaattac cagttattga
    15781 gcgtgtcaaa ttccaccgtt ggaatctggg tgatggaacg attacagaaa atgagccatc
    15841 agcaaatgtt ccagatttca cagctttaga tcatcacttg aagttggtgc aagtaggaac
    15901 tcaaactgtt ttcgaacaaa ctccagttga gttagctgaa cagggtgttg tcttcacaga
    15961 ctttcactca gctttagaag aaattccaga gctgatcgaa gaattcttca tgtcatctgt
    16021 taagtatgat gatgacaagt tggcggctta ccacacagct tactttaaca gtggtgctgt
    16081 actctatatt ccagataacg tagaaatcac agagccaatt gaaggaattt tctaccaaga
    16141 tagcgatagc aatgtgccgt ttaacaagca tattatgatt atcgctggta aaaattctaa
    16201 gattagttat ctggagcgtt tagagtcacg cggtgaagga agtgacaaag caactgccaa
    16261 tatcacagtg gaagtgattg cacattctgg tgcgcaagtc aagtttgctg ctatcgaccg
    16321 tctaggtgaa aacgtcactg cctacattag ccgtcgtggt aaattaggca acgatgcaag
    16381 tattgactgg gctatcggtg tcatgaacga aggaaatgtc gttgctgatt ttgatagtga
    16441 cttgattggt aatggtagct atgctgacct caaggttgta gctctttcaa gtggtcgtca
    16501 ggtacaaggg attgatactc gtgtaactaa ctatggctgc aactctatcg gaaatatcct
    16561 acaacatggg gttatccttg aaaaagcaac tttgactttc aatggtatcg gccacatcat
    16621 caagggtgct aagggagcag atgcccaaca agagagccgt gttctcatgc tttcagacca
    16681 agcgcgttca gatgctaacc caattctttt gattgatgaa aatgatgtca ctgcaggaca
    16741 cgcagcgtct atcggacaag ttgatccaga agacatgtat tacctcatga gtcgtggatt
    16801 ggataaggca actgcagagc gtttggttgt tcgtggtttc cttggatctg ttatcgtgga
    16861 gattccagtc aaggaagttc gtgatgaaat gattgcaact atcgaagaga aattgtcaaa
    16921 acgctaaggg gaagcctatg ttagatgtag aagcgattcg caaggatttt ccaattttag
    16981 atcagattgt caatgatgaa cctctggtct atctggacaa tgctgcgacg acacaaaaac
    17041 cactagtagt tctgaaagct attaacagtt actatgagca ggacaatgcc aatgttcacc
    17101 gtggtgtcca taccttagcg gaacgagcga cagcttctta tgaagctgct cgtgaaacca
    17161 ttcgtaagtt tattaatgca ggctctacaa aggaagttct ctttaccaga ggaacgacaa
    17221 ccagccttaa ctgggtggca cgctttgctg aggaaattct cactgaggga gaccaggtct
    17281 tgatttcagt aatggaacac cattctaata tcattccatg gcaggaagct tgtcgaaaga
    17341 ctggagcaga gcttgtctat gtctatctta aagacggtgc cttggatatg gaggatttgc
    17401 gagctaaatt gactgataag gttaaatttg tttccctagc tcatgcctcc aatgttcttg
    17461 gtgtggtcaa tccgatcaag gaaatcactc aattagccca ccaagttggg gcaatcatgg
    17521 tagtggatgg tgctcaatct acacctcata tgaagattga tgtccaggac ttggatctgg
    17581 actttttcgc cttttcgggt cacaagatgg ctggtccgac tggtatcggt gtcctttacg
    17641 gcaaagaaaa gtatcttgag caaatgtctc cagtagaatt tggcggcgag atgattgatt
    17701 ttgtctacga gcaatccgct agttggaagg aattgccttg gaaatttgag gctggaacgc
    17761 caaatatggc aggagctatt ggacttgcga ctgcagttga ttatctggaa aagattggta
    17821 tggatgccgt tgaagctcat gaacaggaat tgattgcgta cgtctatcca aaactgcagg
    17881 caattgaggg attgaccatt tacggttctc aggatttggc tcaacgttcg ggtgttattg
    17941 cctttaacct aggtgatctc catcctcacg atcttgcgac ggctctggat tatgaaggag
    18001 tggctgttcg tgctggtcac cattgtgcgc aacccttgct tcagtatttg gaagtctcag
    18061 caacagctcg tgcaagtttt tatatctata ataccaaggc agattgcgac aaactagtcg
    18121 atgccctaca aaagacaaag gagtttttca atggcacttt ctaaactaga tagcctttat
    18181 atggcagtgg tagcagacca ttcgaaaaat ccacatcacc aagggaagtt agaagacgct
    18241 gagcaaatca gtctcaacaa tccgacttgt ggagatgtca tcaatctctc tgtcaagttt
    18301 gatgcagagg accgtttgga agatattgct tttctaaatt caggatgcac gatttcaact
    18361 gcttctgcta gtatgatgac agatgccgtt ttaggaaaaa ccaaacaaga aattttagaa
    18421 ctggcgacta ttttttctga aatggttcaa gggcaaaaag atgagcgtca agaccaactt
    18481 ggagacgcgg cattcttgtc aggtgttgcc aaattccctc aaagaatcaa gtgtgcaacc
    18541 ctagcttgga atgcccttaa gaaaacaatt gaaaatcaag aaaaacagta agacaagttt
    18601 cttttgtctt atgaattatt agaaatgaag aaagaaagga tattatggct gaagaaagag
    18661 tagaaccaaa accaattgac cttggtgaat ataaatttgg tttccatgac gatgtagagc
    18721 ctgtcttatc gacaggaaaa ggactcaacg aaggtgttat tcgtgaatta tctgctgcta
    18781 agggtgagcc tgagtggatg ttggagttcc gtttgaagtc ttatgaaacc ttcaaaaaaa
    18841 tgcccatgca aacttgggga gcagacttgt cagagattga ctttgatgac ttaatctact
    18901 accaaaaacc atctgacaaa ccagcccgtt cttgggatga tgtacctgaa aagattaaag
    18961 aaacctttga acgtatcggg attccagaag ctgaacgtgc ttatttagca ggggcttctg
    19021 cccagtacga gtcagaagtg gtttaccaca acatgaagga agagttccaa aaattaggta
    19081 ttatctttac agatacagat tccgcactca aggaataccc agacttattt aatcaatact
    19141 ttgcgaagtt ggtaccgccg acagataaca agttggcagc cctcaactca gcagtatggt
    19201 cgggtggaac ttttatctac gtgccaaaag gtgtcaaggt agatattcca cttcaaactt
    19261 atttccgtat caataacgaa aatataggtc agttcgaacg taccttgatt atcgttgatg
    19321 agggagcaag cgtccactac gtagaaggat gtacagcacc aacatattca agcaatagct
    19381 tacacgctgc cattgtagaa atttttgctt tggacggagc ttatatgcgt tatacaacta
    19441 tccaaaactg gtctgataac gtctataact tggtaacaaa gcgtgctaag gctcaaaagg
    19501 atgccactgt tgagtggatt gatggaaact tgggtgccaa aacgactatg aaatatccat
    19561 ctgtttacct tgatggagaa ggagcgcgtg gtaccatgct ctctatcgcc tttgctaatg
    19621 cagggcaaca ccaagacacg ggtgctaaga tgattcacaa tgctccacat accagctcgt
    19681 ctattgtgtc taaatccatc gctaaaggtg gaggaaaggt tgactaccgt ggacaagtca
    19741 cctttaacaa gaactctaag aaatctgttt cccacattga atgtgatacc attatcatgg
    19801 atgacttgtc agcatcagat actattccat ttaatgaaat tcacaactcg caagtggctt
    19861 tggaacacga agccaaagta tctaagattt cagaagagca attgtattat ctcatgagcc
    19921 gtggattgtc agaatctgag gcaactgaaa tgattgtcat gggatttgta gaacccttta
    19981 caaaagaact tccaatggaa tacgcagttg agctgaaccg cttgattagc tatgaaatgg
    20041 agggatcagt tggataaaat ttgattttat actcttcgaa aatctcttca aaccacgtca
    20101 gcatcgcctt atcgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac
    20161 agtgttttga gcaacctgcg gctagcttcc tagtttgttc tttgattttg aagatgaact
    20221 tgtatcaaaa aatcgcggtt taaaatcgcg attttttata atttctcgtt aacaaagcgg
    20281 acaaactgat tccaccaaac ttttaagaag aaggcttttt caattttctt gtctgctacc
    20341 atttcgaaac tagggcgctc tgtggtgatg taaccttgac caatcaagtc cttgtcttca
    20401 taagtcaaat ggccaaccac tgttccagct tcaagtggtg ctgggattgc tttggaatca
    20461 ggtgtgaatt gaacagattg agaagattga ttcccaacac gttcgattag atagatatcc
    20521 tctggagcca ctgcagttac tgtatcttct tttccatctt gtacaggggc tttgctatct
    20581 tgataggcat cgccttgttg aacgattttg cgaagtgtaa atgtagaaga aatataatcc
    20641 attagggaag atgtagctgt aaatcgagcg taaggattat tgtcttgatg atctgcattt
    20701 aaaacaactg tgatgactct catgcctttt tcgacagtag taccaacaaa agactctcca
    20761 gccttatctg ttgttcctgt ttttagccca tcaaaaccac cacggtaagc aggcatacct
    20821 tctaacatgt agttggttga agtgattgtc atcccagcaa aagtagaaga aggttttttg
    20881 gtgatttcta agacttgtgg gtattttttg atgaggttgc gagcaacgat agcgacatca
    20941 taagcactaa gcttattttc ctcatctttt ttagaacctg ggtaaatgtt atcccctaga
    21001 gtttcattgt taagacctgt cgtattgaca acagtggcat cctgaattcc ccattccaag
    21061 agttttgccc gcatcatatc gacgaaatct ttttctgagc cagcaatttt ctcagctagg
    21121 gcaatagcgg cgctgttggc actagatacc agagttgctt caagcaactc ttcgacagta
    21181 taattacggg cctccatagg aatattactg gcttcagaat ttgtcgtcaa ttgataagga
    21241 taatcagaaa tatctacagg agtggagagg gtaatacttc cgttttccaa agcttcatag
    21301 actagataaa cagtaatcaa ttttgttatg gaagcaattt cgacaggttg cgttgcatcc
    21361 ttctcataga gaattttacc agtatttgcc tcaacagcaa tcgcatgttt agcggcaatg
    21421 gtaaaatctt gagcaacagc agtagaaaca ccccctaaaa gagagacagt taacaaagtt
    21481 aaaaatattt ttttcatagt agtcttattc tatcataaag aaaaaaaata ttcttgcttt
    21541 aataattcat ctgttaagct ttttgaaaat atggtaaaat aaagtgaggg aggtaactca
    21601 tgtttcgtag aaataaatta tttttttgga ccacagaaat tttactctta accatcatct
    21661 tttacctatg gagacagatg ggatctttga ttaacccttt tgttagcgtg cttaatacaa
    21721 ttatgattcc atttttatta gggggctttc tttattattt gacaaaccct attgttactt
    21781 tcttaaataa agtctgtaaa ctcaatcgtt tgcttggtat tttaattacc ttgtgtactt
    21841 tggtctgggg aatggtcata ggtgttgtct atctcttacc tattttgatt aatcagttat
    21901 ctagtttgat tatatctagt caaactattt atagtcgagt acaagactta atcatagact
    21961 tatctaatta tcctgcgctc cagaatttgg atgtagaagc tacaattcag cagttaaact
    22021 tatcctatgt tgatattctt caaaatatcc taaatagcgt atcaaatagt gtggggagcg
    22081 tcttgtcagc tcttatcagt actgttttga ttttgattat gactccagtt tttttggttt
    22141 atttcttatt agatggacat aaattcttgc ccatgcttga aagaacgatt ctaaagaggg
    22201 atcgcttgca tattgcaggc ttattaaaga atttaaatgc gacgattgct cgctatatta
    22261 gtggagtttc gattgacgca atcattatag gttgtttggc ttatattggc tatagtatta
    22321 ttggtttaaa atatgcttta gtttttgcca ttttttctgg tgtagccaat ttaattcctt
    22381 atgtggggcc aagtattggt ttgattccta tgatcatcgc aaatatattc actgatcccc
    22441 atagactgct gattgcagtg atttatatgc ttgttgttca gcaggtagat ggcaatatct
    22501 tatatcctcg aattgtagga agtgttatga aggttcatcc aatcacgatt ttagttttac
    22561 ttttgttgtc aagcaatatc tatggtgtag ttggaatgat tgtcgcagtg ccaacctatt
    22621 ctatcttgaa agaaatttct aagttcttat cccgtttgta tgaaaatcat aaaataatga
    22681 aagaacgaga aagagaatta gctaagtaaa agtcaggaga accctgattt ttctttactg
    22741 gaagtggcct ttagattaga agactgaaaa taagttaaag tcttaaacta attttcacag
    22801 ctaagaatag tagaagttaa tctgataaaa atcgaaaaaa ccagtggaat tccgtgtcag
    22861 ggtaagttcc actggttttc atagtctatt aaagttcgaa tgaaacctat ttatagtata
    22921 ttgaaactag aatagtacac ctctaattct aaaacattgt tagaaatcga tttgactgtc
    22981 ctgatctatt cgtcctattc ttatttcatt ttactatatt ttggtgcaat aagtgaaaag
    23041 tagtccgaat aatataagga ttgattttat agtttttaaa ctcaaatgaa ttaaaataaa
    23101 gagagtacga aaattctcat ctgaaagtat tttagaataa ttctcttcgt gaatttcttc
    23161 aaaacagata gcttcatctt aggtatgtgt taattggatt tcgtaagctc tatttacaat
    23221 cgtaaagtta tgcactgaaa aagttgtagt tagtcttcca gtttgctaaa tttctcgaat
    23281 agtatctttt ttaggtatgt gatttctttt tgcatttttg agttagataa ggtataatgg
    23341 ttttattgtc ttttggggtc gttacggatt cgacaggcat tatgaggcat attttgcgac
    23401 tcgtgtggcg acgtaaacgc tcagttaaat ataactgcaa aaaataacac ttcttacgct
    23461 ctagctgcct aaaaaccagc aggcgtgacc cgatttggat tgctcgtgtt caatgacagg
    23521 tcttattatt agcgagatac gattaagcct tgtctagcgg cttgataaga gattgataga
    23581 ctcgcagttt ctagacttga gttatgtgtc gaggggctgt taaaataata cataacctat
    23641 ggttgtagac aaatatgttg gcaggtgttt ggacgtgggt tcgactccca ccggctccat
    23701 tattcctttg cattcttttg cattccttgg taaaacgttg ttaaatcaac gttttttatt
    23761 tttatctttg gtattccttt gcattctttt gctaaaaagg gagtcacaaa cagaccctat
    23821 tttaaaaaaa ggatagaaaa aaggatacaa catttgtcgc atcctaaaaa taatcttttt
    23881 tcgacggaag acatgggatt cgaacccacg cacgctatta cacgcctacc gcgtttccaa
    23941 cacggcctct taagcctctt gagtaatctt ccaatactta ctcaaatagt ctaccataaa
    24001 ggctcttatc ttgcaataaa aattctagaa ataagaaaaa tgatagattt tgaaagaaaa
    24061 tgataaaaaa tgcttgactt caaaagaaag tatgatagaa tgaatagtgt aaacgataac
    24121 aggaggtgat tcggtgttaa aaacagagcg gaagcaactg attttagagg agttaaatca
    24181 acatcatgta gtttctctag aaaaattagt tagtttgcta gaaacgtcag aatcaacggt
    24241 tcgaagagac ttggatgagt tggaagcgga aaacaagctt cgtcgtgtgc atggtggagc
    24301 agaactcccc cactccttac aggaagaaga aaccattcaa gaaaaatcgg tcaaaaacct
    24361 tcaagaaaag aagttgctgg ctcagaaagc agcctctctc attaaagaaa aagatgtcat
    24421 ctttatcgat gctggaacaa caactgcttt tttgattcat gaattggtca ataagaatgt
    24481 tacagttgtg accaactcca ttcaccatgc cgctcagttg gttgaaaagc agattccaac
    24541 tgtcatggtt ggaggaaacg tcaagacggc gacagatgct agtatcgggg gcgttgctct
    24601 taaccagatt aaccaattgc actttgaccg tgcctttatc ggaatgaatg gtgttgacga
    24661 tggctattat acgactcctg atatggagga gggagctgtg aaaagagcta ttttggagaa
    24721 tgccaagcag acctacgtct tggtggattc gtcaaaaatt ggacaaactt gctttgccaa
    24781 ggtagcacca ctcaaacgcg ctatcgttat cactagtcaa gggcatgagc tcttgcaggt
    24841 tattaaggag aaaacggagg taatagaagt atgatttata cagtcacact caatccatcc
    24901 attgactata tcgttcgttt ggaccaagtc aaagttggta gtgtaaatcg tatggacagt
    24961 gatgataagt ttgctggtgg gaaaggaatc aatgtcagcc gtgtcttgaa acgtttgaat
    25021 ataccaaata cagcgacggg atttatcggt ggctttactg gtaaatttat cacagatact
    25081 ttagcagagg aagaaatcga gacacgtttt gtccaggtgg cagaagatac tcgtatcaat
    25141 gttaaaatca aagcagacca agaaacagaa atcaacggaa cgggtccaac tgttgaaccg
    25201 gttcagctag aagaattgaa agctatttta tctagtctga cagcagaaga tacagttgtc
    25261 tttgcaggtt caagtgctaa aaatctaggc aatgttatct ataaggattt gatttccttg
    25321 acgcgccaga ctggtgcgca agtggtctgt gactttgaag gacagacctt aattgatagt
    25381 ttggactacc agcctcttct tgtaaaacca aacaatcatg aacttggagc gatttttggg
    25441 gttaaactcg aaagtttaga tgaaattgag aaatacgctc gtgagttact ggctaagggt
    25501 gctcaaaatg ttattatctc tatggctggt gatggcgccc ttcttgtcac atctgaggga
    25561 gcttacttcg ctaaaccaat caaaggaaca gtcaaaaatt cagttggagc tggtgattct
    25621 atggttgctg gattcacagg tgaatttgtc aaatcaaaag acgcagtaga agccttcaaa
    25681 tggggagtgg cttgcggaac ggcaactacc ttctcagatg acttggcaac ggcggaattt
    25741 attaaagaaa catatggaaa agttgaggta gaaaaaagat gaaaattcaa gacctattga
    25801 gaaaagatgt catgttgcta gatttgcagg caactgaaaa aacagctgtc atcgacgaga
    25861 tgattaaaaa tttgacagag cacggttatg taacagattt tgaaacattt aaagaaggaa
    25921 ttttggcgcg tgaagctttg acttctactg gtttgggtga tggaatcgca atgcctcaca
    25981 gcaaaaacgc tgctgtcaaa gaagcgacag ttctatttgc taagtcaaat aagggtgttg
    26041 actacgagag cttggatgga caagcaactg acctcttctt catgattgca gctccagaag
    26101 gtgccaatga tactcacttg gcagccttgg cagaattgtc tcaatacttg atgaaagacg
    26161 gttttgcaga caaacttcgt caagcaacat ctgcagacca agttatcgaa ctttttgacc
    26221 aagcttcaga aaaaactgag gaacttgttc aagcacctgc taatgactct ggtgacttta
    26281 tcgtagctgt tacagcttgt acaacaggta ttgcccacac ttacatggcc caagaagccc
    26341 ttcaaaaagt agctgctgaa atgggggttg gtatcaaggt cgaaaccaac ggtgctagcg
    26401 gtgttggaaa tcaactaact gcagaagata tccgtaaggc taaagctatt atcattgcag
    26461 cagacaaggc cgttgaaatg gatcgatttg atggaaaacc attgatcaat cgtccagttg
    26521 ctgacggtat ccgtaagaca gaagagctaa ttaacttggc tctttcagga gatactgaag
    26581 tctaccgtgc cgctaatggt gccaaagctg caacagcctc taacgaaaaa caaagccttg
    26641 gtggtgcctt gtacaaacac ttgatgagtg gtgtatctca aatgttacca ttcgttatcg
    26701 gtggtggtat catgattgcc cttgccttct tgattgacgg tgctttgggt gttccaaatg
    26761 aaaaccttgg caatcttggt tcttaccatg agttagcttc tatgttcatg aaaattggtg
    26821 gagctgcctt tggtttgatg cttccagtct ttgcgggtta tgttgcctac tctattgctg
    26881 aaaaaccggg tttggtagca ggtttcgtgg ctggtgctat tgccaaagaa ggttttgcct
    26941 ttggtaaaat tccttatgcc gcaggtggtg aagcaacttc aactcttgca ggtgtctcat
    27001 ctggtttcct aggtgccctt gttggtggat ttatcgcagg tgccttggtt cttgccatca
    27061 agaaatacgt taaagttcct cgttcactcg aaggtgctaa atcaatcctt ctattgccac
    27121 ttcttggaac aatcttgaca ggatttgtta tgctagctgt gaatatccca atggctgcaa
    27181 tcaacactgc tatgaatgac ttcctaggcg gtcttggagg aggttcagct gtccttcttg
    27241 gtatcgtcct tggtggaatg atggctgttg acatgggtgg accagttaat aaagcagctt
    27301 atgtctttgg tacaggtacg cttgcagcaa ctgtttcttc aggtggttct gtagccatgg
    27361 cagcagttat ggctggagga atggtgccac cacttgcaat ctttgtcgca actcttcttt
    27421 tcaaagataa atttactaag gaagaacgta actctggttt gacaaacatc atcatgggct
    27481 tgtcatttat cactgaggga gcgattccat ttggtgccgc tgacccagct cgtgcgattc
    27541 caagcttcat ccttggttca gcagtagcag gtggactcgt tggtcttact ggtatcaaac
    27601 tcatggcgcc acacggagga atcttcgtta tcgcccttac ttcaaatgct ctcctttacc
    27661 tcgtttctgt cttggtagga gcaatcgtaa gtggtgtggt ttatggttac ctacgcaaac
    27721 cacaagcata aaaaatagaa aaatgaaaag attggaccgt ttggtgcagt ctttttctct
    27781 tcccgaaatg cctgtgaaat atggtataat agaagaatgg caaacaagaa tacaagtaca
    27841 acaagacgga gaccgtctaa agcagaactg gaaagaaaag aagcgattca acgaatgttg
    27901 atttcgttag gaattgcgat tttattgatt ttcgcagcct tcaaattagg ggctgcaggt
    27961 ataacccttt ataatttaat tcgcttgcta gtgggtagcc tagcttatct ggcgatattc
    28021 ggcctattaa tctatctctt ctttttcaag tggatacgaa aacaggaagg actcttatct
    28081 ggctttttca ccatatttgc tggcttactc ttgatttttg aggcctactt ggtttggaaa
    28141 tatggtttgg acaagtccgt tctaaaaggg accatggctc aggttgtgac agatctgact
    28201 ggttttcgaa cgactagctt tgctggaggg ggcttgatcg gggtcgctct ttatattcca
    28261 acagcctttc tcttttcaaa tatcggaact tactttattg gttctatctt gattttagtg
    28321 ggttctctcc tagtcagccc ttggtctgtt tacgatattg ctgaattttt cagtagaggc
    28381 tttgccaaat ggtgggaagg gcacgagcgt cgaaaagagg aacgctttgt caaacaagaa
    28441 gaaaaagctc gccaaaaggc tgagaaagag gctagattag aacaagaaga gactgaaaaa
    28501 gccttactcg atttgcctcc tgttgatatg gaaacgggtg aaattctgac agaggaagct
    28561 gttcaaaatc ttccacctat tccagaagaa aagtgggtgg aaccagaaat catcctgcct
    28621 caagctgaac ttaaattccc tgaacaggaa gatgactcag atgacgaaga tgttcaggtc
    28681 gatttttcag ccaaagaagc ccttgaatac aaacttccaa gcttacaact ctttgcacca
    28741 gataaaccaa aagatcagtc taaagagaag aaaattgtca gagaaaatat caaaatctta
    28801 gaagcaacct ttgctagctt tggtattaag gtaacagttg aacgggccga aattgggcca
    28861 tcagtgacca agtatgaagt caagccggct gttggtgtaa gggtcaaccg catttccaat
    28921 ctatcagatg acctcgctct agccttggct gccaaagatg tccggattga agcaccaatc
    28981 cctgggaaat ccctaatcgg aattgaagtg cccaactccg atattgccac tgtatctttc
    29041 cgagaactat gggaacaatc gcaaacgaaa gcagaaaatt tcttggaaat tcctttaggg
    29101 aaggctgtta atggaaccgc aagagctttt gacctttcta aaatgcccca cttgctagtt
    29161 gcaggttcaa cgggttcagg gaagtcagta gcagttaacg gcattattgc tagcattctc
    29221 atgaaggcga gaccagatca agttaaattt atgatggtcg atcccaagat ggttgagtta
    29281 tctgtttaca atgatattcc ccacctcttg attccagtcg tgaccaatcc acgcaaagcc
    29341 agcaaggctc tgcaaaaggt tgtggatgaa atggaaaacc gttatgaact ctttgccaag
    29401 gtgggagttc ggaatattgc aggttttaat gccaaggtag aagagttcaa ttcccagtct
    29461 gagtacaagc aaattccgct accattcatt gtcgtgattg tggatgagtt ggctgacctc
    29521 atgatggtgg ccagcaagga agtggaagat gctatcatcc gtcttgggca gaaggcgcgt
    29581 gctgcaggta tccacatgat tcttgcaact cagcgtccat ctgttgatgt catctctggt
    29641 ttgattaagg ccaatgttcc atctcgtgta gcatttgcgg tttcatcagg aacagactcc
    29701 cgtacgattt tggatgaaaa tggagcagaa aaacttcttg gtcgaggaga catgctcttt
    29761 aaaccgattg atgaaaatca tccagttcgt ctccaaggct cctttatctc ggatgacgat
    29821 gttgagcgca ttgtgaactt catcaagact caggcagatg cagactacga tgagagtttt
    29881 gatccaggtg aggtttctga aaatgaagga gaattttcgg atggagatgc tggtggtgat
    29941 ccgctttttg aagaagctaa gtctttggtt atcgaaacac agaaagccag tgcgtctatg
    30001 attcagcgtc gtttatcagt tggatttaac cgtgcgaccc gtctcatgga agaactggag
    30061 atagcaggtg tcatcggtcc agctgaaggt accaaacctc gaaaagtgtt acaacaataa
    30121 aaaaatagct tctttccaag tttggaggga agctattttt ctggctattg attactttta
    30181 tactcttcgc aaatctcttc aaaccacgtc agcttcgcct tgccgtactc aagtactgtc
    30241 tacggctagc ttcctagttt gctctttgat tttcattgag tattattttc tgaagttgga
    30301 gtattgggct gtttttcatt ttcagtggca ggtttacttg tagcaggtgt agtagagtcc
    30361 tgagttgctg ttttctgatc ttcttttttc tcttccttga cgctagattt tggcgtttct
    30421 tcttgttgtg ttttttcttg agaagtgtta ttttccttat ttggagtagt attttcctga
    30481 ggggattctt tttgaatttc tttgacaaag gttgtcgtct ggcttgtcgt aggttctttt
    30541 ttagtatttt tattattatt atccaaggcg ttcatgatcg tgatacccgc ggtaatcaaa
    30601 ccaaggatac taccgatagt agtaatggtt ttttgaaaaa cagtaaagcc ttttttgata
    30661 tgttctgttt tcggttttga agttctacga tagttagaca tacattctct cctttgatta
    30721 tgatttatta tactctgttt ctttaaaaaa atcttaaaaa aagagaaatt gccctttctt
    30781 gtcgcaggct ccgtttcatg atacaataga aggagtgatt ttagaaagcg tgagaaacat
    30841 gatttacttt gataattcgg cgacgaccag gccctatcca gaagcccttg aaacctatat
    30901 gcaggtggct tcaaaaattt taggaaatcc atctagtctc catcgtttgg gagaccaggc
    30961 aacacgaatt ttagatgctt cccgtcaaca gattgcagat ttaatcggta agaaaagtga
    31021 tgaaatcttc tttacatctg gtgggacaga aggggataac tggatcatca agggagtagc
    31081 atttgaaaaa gcccagtttg gcaagcacat catcgtatca gccattgaac atccagcagt
    31141 taaggaatca gccctctggt tgaaagctca aggttttgaa gtggattttg ctccagttga
    31201 taacaaagga tttgtggatg ttgaggcgct agaagatttg ataagacctg atacgaccct
    31261 cgtttccatc atggctgtga acaatgaaat cggctctatc caacctattg aggctatttc
    31321 agaattcttg gcagacaagc caactatttc cttccacgtt gatgcggttc aggcgcttgc
    31381 caagattccg actgaaaagt atctgacaga acgagtggat ttcgcgactt tctctggtca
    31441 caagttccac ggaatccgtg gtgttggttt tatctatatc aagtctggca agaagattac
    31501 gcctctttta acaggtggtg gtcaggaacg tgattaccgt tcgacaactg aaaatgtggc
    31561 aggaattgca gcgaccgcta aggctctccg tttatctatg gaaaagctag atatctttag
    31621 gagcaagact gggcagatga aggcagtgat tcgtcaagca cttctggact atccggatat
    31681 atttgtcttt tcagatgagg aagacttcgc ccctcatatt ctgacttttg gaatcaaggg
    31741 tgttcgtggt gaggtcattg ttcacgcctt tgaagactat gatattttca tctcaacgac
    31801 ctcggcttgt tcgtccaagg ctgggaaacc agccggaacc ctgattgcta tgggagtgga
    31861 caaggataag gctcagtcag ctgtgcgtct tagtctagac cttgaaaatg atatgagtca
    31921 ggtcgagcag ttcttgacca agctaaaatt aatttacaat caaactagaa aagtaagata
    31981 ggagcattca tgcagtattc agaaattatg attcgctacg gtgagctgtc aaccaagggc
    32041 aaaaatcgta tgcgtttcat caataaactt cgcaataata tttcagacgt tttgtctatc
    32101 tatccccaag ttaaggtaac agcagatcgc gaccgtgccc acgcttacct caatggagca
    32161 gattacacag cagtagcaga atcgctcaaa caagtatttg gaattcaaaa cttttcccct
    32221 gtttataagg ttgaaaaatc tgtagaagtt ctgaagtctg ctgtccaaga gattatgcag
    32281 gacatctaca aggaaggcat gacctttaaa atctctagca agcgtagcga ccacaccttt
    32341 gaattggaca gtcgtgaact caaccaaacg cttggagggg ctgtattcga agccattcca
    32401 aacgtacaag ctcaaatgaa aagtcctgac atcaatcttc aggtggagat acgtgaagaa
    32461 gcagcctatc tttcttatga aaccgttcga ggggcaggtg gattaccagt gggaacttct
    32521 ggtaagggca tgctcatgtt gtcaggggga atcgattccc ctgtagctgg ctatctagcg
    32581 cttaaacgag gggtagatat agaggcagtt cactttgcca gcccacctta cacgagtcct
    32641 ggtgctctta aaaaagccca agatttgacc cgtaaattaa ccaaatttgg gggaaatatc
    32701 cagtttatcg aagttccttt tacagagatt caagaggaaa tcaaagccaa agcgccagaa
    32761 gcctacctta tgaccttgac gcgtcgtttt atgatgcgta ttactgaccg tattcgtgag
    32821 gtacgaaatg gtttagttat catcaatggg gaaagtctag gtcaagtagc cagccaaacc
    32881 cttgaaagta tgaaggctat caatgctgtt accaacactc ccatcattcg tcctgtggtt
    32941 accatggaca agttggaaat cattgacatc gcccaggaaa tcgatacctt tgacatttca
    33001 atccaaccgt ttgaagactg ttgtactatt tttgcaccag atcgtccaaa aacaaatcct
    33061 aaaattaaga atgcggagca gtacgaagcg cgtatggatg ttgaaggctt ggttgagcga
    33121 gcagtggctg gaatcatgat tactgaaatc acacctcaag ccgaaaaaga tgaagttgat
    33181 gacttgattg acaatctgct ctaattcaga aaatccaaaa gaatagcgaa aatcagtaaa
    33241 aaaagttagt tttttctcta aaaacaggta aaaaactaac tttttttatt tttatgatat
    33301 aatgatataa aattttgaat atagagagtt ttctgacaat gaatcaatcc tacttttatc
    33361 taaaaatgaa agaacacaaa ctcaaggttc cttatacagg taaggagcgc cgtgtacgta
    33421 ttcttcttcc taaagattat gagaaagata cagaccgttc ctatcctgtt gtatactttc
    33481 atgacgggca aaatgttttt aatagcaaag agtctttcat tggacattca tggaagatta
    33541 tcccagctat caaacgaaat ccggatatca gtcgcatgat tgtcgttgct attgacaatg
    33601 atggtatggg gaggatgaat gagtatgcgg cttggaagtt ccaagaatct cctatcccag
    33661 agcagcagtt tggtggtaag ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc
    33721 cttttatcaa gcacaaaaca ggttggtttg atggcatgat gacgacaggt tgctctatgg
    33781 gagcctatca tgcactcaat ttcttcctcc agcatccaga tgtctttacc aaagtgattg
    33841 ctctcagtgg tgtttacgac gcacgtttct ttgtcggcga ttactacaac gatgatgcta
    33901 tttaccaaaa ctcgccagta gattatattt ggaaccaaaa cgatggctgg tttattgacc
    33961 gttaccgtca ggcagagatt gtgctgtgta cggggcttgg agcctgggaa caagatggtt
    34021 taccatcctt ttacaagctc aaagaagcct ttgaccagaa acaaattcca gcctggtttg
    34081 ctgaatgggg acatgatgtc gcccacgact gggaatggtg gcgtaaacaa atgccttatt
    34141 tcctcggtaa tctctattta taaaaggagt tacctatgaa ttaccttgtt atttctccct
    34201 actatccaca aaactttcaa cagtttacca tcgaactagc taataaaggc atcacagtct
    34261 tgggaattgg tcaagagtct tacgagcaat tggatgagcc cttgcgcaat agcttgaccg
    34321 agtattttcg tgttgataat cttgagaaca tagatgaagt caaacgtgca gttgcttttc
    34381 tcttttataa acatggtcca attgaccgca tcgagtctca caatgaatac tggcttgagc
    34441 tagacgcaac actcagagaa caattcaatg tttttggtgc caaaccagag gatctcaaaa
    34501 agacgaaata taagtctgaa atgaagaaac ttttcaaaaa agcaggtgtt cctgtggtac
    34561 ctggagctgt tatcaagacg gaagcagatg ttgatcaagc agtgaaagaa atcggtcttc
    34621 caatgattgc caaacctgat aatggagtgg gagcagccgc aacctttaaa cttgagacag
    34681 aagacgatat caatcacttc aagcaagaat gggaccattc aaccctttat ttctttgaaa
    34741 aatttgtcac ttccagcgaa atctgtacct ttgacgggct cgtggacaag gatggaaaga
    34801 ttgtcttctc aacaaccttt gactacgcct atacaccgct tgacctcatg atttataaga
    34861 tggacaattc ttattatgtg ctcaaggata tggatcctaa actgcgcaag tatggggaag
    34921 caattgtcaa agaatttggt atgaaagaac ggtttttcca tattgagttc ttccgtgagg
    34981 gggacgatta tattaccatc gagtacaata accgccctgc aggtggtttt accattgatg
    35041 tttataactt tgctcattcc ttggaccttt atcgtggcta tgcagctatt gtcgcaggag
    35101 aggagttccc ggcgtcagac tttgaaactc agtattgttt ggctacttct cgccgtgcaa
    35161 atgctcacta tgtttattca gaagaggatt tgcttgccaa atatagccag cagttcaagg
    35221 ttaaaaaagt catgccagct gccttcgcgg aacttcaagg agattacctg tatatgctga
    35281 caactccgag tcgacaagaa atggatcaga tgattgctga tttcggacaa cgtcaagaat
    35341 aagaactatc ggattaagga aattcactcc cttaatcctt ttgttttgtc tggtaaaaaa
    35401 taagagcatc ctaacaaggt agctatcata aaacttgttc gataactatt tgaagcagga
    35461 ttaggtggct agaaattgaa ttttaacatt tcaatttagt catagtattg tgttttcgta
    35521 tccttaaatc agctaaaagg atccatgacg acacctatac gatatagttt tcaggatacc
    35581 aaaccagtct attaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
    35641 tgctcaaaac actgttttga ggttgtggat agaactgaca gagtcagtat catataccta
    35701 cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa gagtataaaa tattcaggtg
    35761 acgcatagat atagttaatt gaagctttgt ttgaaatctg ataaaataat gatattacta
    35821 agttttaaaa actaaagaaa agggaagata tgattacagg cgaattaaaa aataaaatcg
    35881 atcagctgtg ggaaattctt tggacagaag gaaacgcaaa tcctttaaca aatattgaac
    35941 agttgactta tctcttattt atgaaagatt tggatagtgt cgagcttgga cgtgaaagtg
    36001 atgctgaatt tctagggatt ccttatgagg gagtttttcc aaaagataaa cctgaatacc
    36061 gttggtcaac ttttaaaaat ataggagatg ctcaggaagt ttatcgttta atgactcagg
    36121 agatttttcc gtttattaaa aatctcaagg gggatacaga tgatacagcc ttttcacgat
    36181 atatgcgaga agctattttt caaataaata aacctgctac gcttcaaaag gcaatttcta
    36241 tcttagatgt ttttccaact aggggattag atgtagattt tgataatgac aaacaaagta
    36301 ttactgatat cggagatatc tatgaatatc tgttatcaaa attgtcgacc gcaggtaaaa
    36361 atggacagtt ccgtacacct cgtcacatca tcgatatgat ggttgagttg atgcaaccga
    36421 ctatcaaaga tatcatctca gatcccgcta tgggttctgc tggcttctta gtatctgcta
    36481 gccgttactt aaagcgtaag aaagatgaat gggaaaccaa tacagataat atcaatcatt
    36541 ttcataatca gatgtttcat ggaaatgata cggatacgac tatgttgaga cttggggcga
    36601 tgaacatgat gctacatgga gtagaaaatc cacaaatcag ttaccttgac tcgctgtctc
    36661 aagataatga agaagccgat aaatatactt tggttttagc aaatcctcct tttaagggct
    36721 cacttgacta caattcaacc tctaatgacc ttcttgcaac cgtaaaaacc aaaaaaacag
    36781 aattactctt tctttctctt ttcttgcgaa ctttaaaacc aggtggacga gcagcagtta
    36841 tcgtacctga tggtgtcctt tttggttcgt ctaaagctca taaaggaatt cgtcaggaaa
    36901 ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc tagtggtgtg ttcaagcctt
    36961 atgctggagt ttcaactgcc attctcatct ttacaaaaac tggtaatggt ggtactgaca
    37021 aagtctggtt ttacgatatg aaagcggatg gtttaagttt ggatgataag cgacaaccga
    37081 ttagcgacaa tgatattcca gatattatcg aacgctttca tcatcttgaa aaagaagcag
    37141 aacgtcagag aacggatcaa tctttctttg ttccagttgc tgagataaag gaaaatgatt
    37201 atgatttgtc tatcaataaa tataaagaga ttgagtatga aaaagttgag tatgaaccaa
    37261 cagaggtcat cttaaagaaa atcaatgatt tagaaaaaga aattcaagct ggcttggctg
    37321 aattagaaaa attactcaag tagggaggtg gctgtatgaa aaaagtgaag ttgggggaag
    37381 tcttatctct aaaaaaaggc aagaaagcca ctgtacttgc tgaacaaaca actctaagcc
    37441 aacgttatat tcaaatagat gatttaagaa ataataataa tttaaaattc actgaaagtt
    37501 taaatatgac tgaagcactc ccagatgata ttctgatagc atgggatgga gctaatgcag
    37561 gaacagttgg ttatggatta tcgggagctg ttggtagtac aattacggtc ttaaaaaaga
    37621 atgagcgata caaagaaaaa attatatcag attacttggg agtctttttg gaaagtaaat
    37681 cgcagtattt acgagaacat tcaacaggtg caacaattcc tcatttaaac aagaatatat
    37741 tacttgattt acaattagaa ttgctaggta tcgaagaaca agagaacatt atctgtattc
    37801 ttaatacgat taaagggctt attactaaaa gaaaattgca gttagatgaa ctaaacttgc
    37861 tcg
//
LOCUS       DAVBOU010000017        35498 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBOU010000017 DAVBOU010000000
VERSION     DAVBOU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35498
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.017"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..175)
                     /locus_tag="VQ879_000927"
                     /pseudo
     CDS             complement(1..175)
                     /locus_tag="VQ879_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            161..646
                     /locus_tag="VQ879_000928"
     CDS             161..646
                     /locus_tag="VQ879_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3143096.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            730..1437
                     /locus_tag="VQ879_000929"
     CDS             730..1437
                     /locus_tag="VQ879_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143097.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1438..2769
                     /locus_tag="VQ879_000930"
     CDS             1438..2769
                     /locus_tag="VQ879_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3143098.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2936..3811
                     /locus_tag="VQ879_000931"
     CDS             2936..3811
                     /locus_tag="VQ879_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3143099.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3929..4792
                     /gene="pstC"
                     /locus_tag="VQ879_000932"
     CDS             3929..4792
                     /gene="pstC"
                     /locus_tag="VQ879_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3143100.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4785..5600
                     /gene="pstA"
                     /locus_tag="VQ879_000933"
     CDS             4785..5600
                     /gene="pstA"
                     /locus_tag="VQ879_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3143101.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5602..6354
                     /gene="pstB"
                     /locus_tag="VQ879_000934"
     CDS             5602..6354
                     /gene="pstB"
                     /locus_tag="VQ879_000934"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3143102.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6369..7019
                     /gene="phoU"
                     /locus_tag="VQ879_000935"
     CDS             6369..7019
                     /gene="phoU"
                     /locus_tag="VQ879_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3143103.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7087..7512
                     /locus_tag="VQ879_000936"
     CDS             7087..7512
                     /locus_tag="VQ879_000936"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143104.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7686..8066)
                     /locus_tag="VQ879_000937"
     CDS             complement(7686..8066)
                     /locus_tag="VQ879_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3143105.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8278..9294
                     /locus_tag="VQ879_000938"
     CDS             8278..9294
                     /locus_tag="VQ879_000938"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3143106.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9316..10215
                     /gene="galU"
                     /locus_tag="VQ879_000939"
     CDS             9316..10215
                     /gene="galU"
                     /locus_tag="VQ879_000939"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3143107.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10633..11565
                     /locus_tag="VQ879_000940"
     CDS             10633..11565
                     /locus_tag="VQ879_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143108.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(11668..12345)
                     /locus_tag="VQ879_000941"
     CDS             complement(11668..12345)
                     /locus_tag="VQ879_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3143109.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(12329..12868)
                     /locus_tag="VQ879_000942"
     CDS             complement(12329..12868)
                     /locus_tag="VQ879_000942"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3143110.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(12880..14010)
                     /locus_tag="VQ879_000943"
     CDS             complement(12880..14010)
                     /locus_tag="VQ879_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3143111.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFVGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITETAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(14078..14776)
                     /gene="dapD"
                     /locus_tag="VQ879_000944"
     CDS             complement(14078..14776)
                     /gene="dapD"
                     /locus_tag="VQ879_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3143112.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(15006..15917)
                     /locus_tag="VQ879_000945"
     CDS             complement(15006..15917)
                     /locus_tag="VQ879_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3143113.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(15982..18447)
                     /locus_tag="VQ879_000946"
     CDS             complement(15982..18447)
                     /locus_tag="VQ879_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3143114.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYSLLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            18589..19845
                     /locus_tag="VQ879_000947"
     CDS             18589..19845
                     /locus_tag="VQ879_000947"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3143115.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(19923..21986)
                     /locus_tag="VQ879_000948"
     CDS             complement(19923..21986)
                     /locus_tag="VQ879_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3143116.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGSGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21988..22266)
                     /locus_tag="VQ879_000949"
     CDS             complement(21988..22266)
                     /locus_tag="VQ879_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143117.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22418..23266
                     /locus_tag="VQ879_000950"
     CDS             22418..23266
                     /locus_tag="VQ879_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3143118.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23888..24460
                     /locus_tag="VQ879_000951"
     CDS             23888..24460
                     /locus_tag="VQ879_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143119.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(25504..27762)
                     /gene="glgP"
                     /locus_tag="VQ879_000952"
     CDS             complement(25504..27762)
                     /gene="glgP"
                     /locus_tag="VQ879_000952"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3143120.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(27788..29305)
                     /gene="malQ"
                     /locus_tag="VQ879_000953"
     CDS             complement(27788..29305)
                     /gene="malQ"
                     /locus_tag="VQ879_000953"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3143121.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGYVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            29855..31126
                     /locus_tag="VQ879_000954"
     CDS             29855..31126
                     /locus_tag="VQ879_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3143122.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            31237..32529
                     /locus_tag="VQ879_000955"
     CDS             31237..32529
                     /locus_tag="VQ879_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3143123.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            32531..33373
                     /locus_tag="VQ879_000956"
     CDS             32531..33373
                     /locus_tag="VQ879_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3143124.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            33626..34426
                     /locus_tag="VQ879_000957"
     CDS             33626..34426
                     /locus_tag="VQ879_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3143125.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            34436..35422
                     /locus_tag="VQ879_000958"
     CDS             34436..35422
                     /locus_tag="VQ879_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3143126.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT        10858 a         7491 c         6675 g        10474 t
ORIGIN      
        1 cttcatagcg tggcatttct ttttaccaga atcattcgct aattcttctt ttagggcgat
       61 tgatttgtac ttccgtcgca tcaatcatta ccgtgtcctc agaactgaga ggagttcttg
      121 aaatcgtaaa accactttga acaagagtta cttcaaccca ttggctccga cggataaaga
      181 agacttgata agaactctag agttagctcc ccatgttgaa ggtggctatt ttagacaaac
      241 aaaaaaagct tcagacacta taaaccttgc tggtaaggga agggcgcttt ataccagtat
      301 ttatttctta ttagaagaaa cgaatccttc acattttcac cgattgacag cagatgaaat
      361 ctggtatttt catgcagaat ccccacttac tgttcacatg attacagcag atggtcacta
      421 cgaagcagtc actttaggcc tggacatatc caaagggcaa caacttcact actgtgttcc
      481 taagggcact atttggggat caacagttga taaggatgat gctctggttt cttgtcttgt
      541 tgctcctggt tttgaatttg aggattttga attatttgaa agggtagatc tactggcgac
      601 ctatccagag cacaaggaga tgattgagcg tttgaccaga tactagtctt tataagcaaa
      661 tttaatctga tttagcaatg ttaggatttc tgataattgt gttataatgt taccaatagg
      721 agataataga tgacaaaaca agtcttatta gtggatgatg aagaacacat tctgaaattg
      781 cttgactacc atttaagtaa ggaaggcttt tctactcaat tggtaacaaa tggacggaag
      841 gccttagctt tggcagaaac agaacccttt gattttatct tgcttgatat catgttacca
      901 caattagatg gcatagaagt ttgtaagcgg ctgagagcca aaggcgtcaa aactccaatt
      961 atgatggttt ctgcgaaaag tgatgaattt gataaggttt tggccttgga attaggggct
     1021 gatgactacc tgaccaagcc ttttagccct agagaattac tggcgcgtgt caaggctgtc
     1081 ctcaggcgaa ctaaaggaaa acaagaagga gatgattcag ataatatcgc tgacaattct
     1141 tggctatttg ggaccttgaa agtataccct gagcgtcatg aagtctacaa ggcgaataag
     1201 ttactgagtt tgaccccaaa agaatttgaa ctcttgctct atcttatgaa acatcccaac
     1261 atgacactga ctagagagcg tcttttggaa cgtatctggg ggtatgactt tgggcaggaa
     1321 acacgtttgg tggacgttca tattggtaag ttgagggaaa aaattgaaga caatcctaaa
     1381 gcccctcaat ttattcgaac cattcggggt tatggttata agttcaagga gttatagatg
     1441 aaacgctacc ttcaattttg gctagtcaat ctaagtgtta gcctcattct gattgcaggg
     1501 atggcattaa cttggatcag taaaggcatc ggtctctttc ttctagccct ttctttggga
     1561 ctaggtggct actggctctt ttgcctttgg aaatgggaag ttgcttttga gaccttgcac
     1621 caacctctct tgaccagtag tgaatacttt ttagaaaaag ggcaagaaga cttaaagtct
     1681 ttggctcagt atgtgtctgg cctaaaaacc aaagtctccc aacaggatca gcaatacaag
     1741 gacctagccg aaacaatgga ggttcttctg tcgcacctaa ccatggggac gtttttagtt
     1801 tccgctcaag gtcagatgtt attatccagt cgctctctgc ctcattattt tcccgatgtg
     1861 gacggcgaca taagttcact tgatgacctc aaacggatgg atattcggaa tttagttcac
     1921 caagcctttg atcaaaaaac aaggttaaaa caagaagtaa gtgggtttca tgagggtgac
     1981 ttgattttag aagtgacagc agttcccgtt tttagcccca cccaatctgt ggaagctgtg
     2041 ctcgtcttgc tatatgattt aacaacgatt agaacttatg aaaagttaaa tttagccttt
     2101 gtctcaaatg cctcccatga attgaggaca ccagttactt cgattaaggg ctttgctgaa
     2161 accattaagg ggatgtcagc tgaagaagaa gcgctcaagg atgactttct agacattatt
     2221 tacaaagaaa gcttgcgtct tgagcatatt gttgagcatc ttcttacctt atctaaggct
     2281 caacaaatgc ctatacaatg gacgaccctt tctttggcag aatttgtaca ggatttgact
     2341 caaagcttgc aacctcagct caagaagaag gatttacagc taaaggtgca ggtgccagat
     2401 gatgtcaccc tcgtatcaga tagtcaatta ctttcccaaa tcttactcaa tcttttatcc
     2461 aatgccatcc gttacactga acaaggggga aaaattgagg tcaagaccca aaaggtgaac
     2521 gaaggcatta agatttctgt atcagataca gggattggta ttagtcaatt agagcaggat
     2581 cgtatttttg aacgttttta ccgagttaat aaaggtcgaa gcagacaaac tggtggcact
     2641 ggtcttggcc ttgccattgt caaagaactc agtcaattat taggtggcca agtcacggtg
     2701 acgagtcagc ttggcagagg cagttgcttc acgatttttc ttcctaacca atctttcgca
     2761 caggactaat aatttttaaa gctattttta ggagcagcca tttttcaaaa gtggcttttt
     2821 ttgattcttt acacaatctt tacatgaatc agggataaac ctttacaaag acttgttaga
     2881 ctataaatgt agtaagccta cacaagaaaa atacatagag ataaaggtga ttattatgaa
     2941 attcaaaaaa atacttactc ttgcagccat tggcttatca ggatttgggc ttgttgcctg
     3001 tggcaatcag tcatctactt ccaaacagtc agcttcagga acgattgagg tgatttcacg
     3061 agaaaatggc tctgggacac ggggtgcctt cacagaaatc acagggattc tcaaaaaaga
     3121 cggtgataaa aaaattgaca acactgccaa aacagctgtg attcaaaata gtacagaagg
     3181 tgttctctca gcagttcaag ggaatgctaa tgctatcggc tacatctcct tgggatcttt
     3241 aacgaaatct gtcaaggctt tagagattga tggtgtcaag gctagtcgag acacagtttt
     3301 agatggtgaa taccctcttc aacgtccctt caacattgtt tggtcttcta atctttccaa
     3361 gctaggtcaa gattttatca gctttatcca ctccaaacaa ggtcaacaag tggtcacaga
     3421 taataaattt attgaagcta aaactgaaac cacagaatat acaagccaac acttatcagg
     3481 caagttgtct gttgtaggtt ccacttcagt atcttcttta atggaaaaat tagcagaagc
     3541 ttataaaaaa gaaaatccag aagttacgat tgatattacc tctaatgggt cttcagcagg
     3601 tattaccgct gttaaggaga aaaccgctga tattggtatg gtttctaggg aattaactcc
     3661 tgaagaaggt aagagtctca cccatgatgc tattgcttta gacggtattg ctgttgtggt
     3721 caataatgac aataaggcaa gccaagtcag tatggctgaa cttgcagacg tttttagtgg
     3781 caaattaacc acctgggaca agattaaata aaatgtttgc tccataaatc tctaaagaga
     3841 tgcagacgtt tcatcgtaca ataagataaa gaaggcaagt agggaggtgt cgtatctccc
     3901 ttactttctt cactagaaag gacaagatgt gacaaaacaa gccttcaaag aagcagtttt
     3961 tagggcaatt tttttcatga gtgcaacagt agctgttgta gctattttgc taatctgttt
     4021 ctttattttt agtaatggct tacctttcat ggctaactac ggctttgccc gttttttatt
     4081 aggcagtgat tggtcgccaa cgaacattcc ggcaagctat ggtattttac caatgatcgt
     4141 tggttcctta ttaattacct taggagcgat tgtgattggg gtgccaacag gcatcttgac
     4201 atcggtgttt atggtttatt attgtccaaa gcccgtctat ggcttcttaa aatcagctat
     4261 caacttgatg gcagccattc catctattgt ttatggtttt ttcggcctac aattattggt
     4321 gccttggatt agaacctttt taggaaatgg catgagtgtc ctaaccgctt cgttactatt
     4381 aggaataatg attttgccaa ccattatcag tttgtcagaa tctgctatcc gaacagttcc
     4441 caaaacgtat tattctggta gcttggctct aggagctagt catgaacgga gtatttttag
     4501 tgtcatcttg ccagctgcga gatctggtat tttatcagca gttattttag gaatcggtcg
     4561 cgcagtaggt gaaaccatgg cagttatttt ggtggcaggc aaccagccaa ttattccaag
     4621 tggactcttt tcaggaacca gaaccttaac aaccaatatt gttctggaaa tggcttacgc
     4681 atcaggtcag catagggaag cccttattgc aacctcagca gttctctttt tccttattct
     4741 cttgattaat gcctactttg cctacttgaa aggaaaatca tcttatgagt aaatacctgc
     4801 taaaacttct cgtttattgt ttttcagctt taacctttgg ctctctcttt ttaatcattg
     4861 gttttatcct catcaaaggc ttacctcatc taagtctatc cctcttttct tggacttata
     4921 cttctgagaa catttccctt atgccagcga ttatttccac cgttattctg gtttttggtg
     4981 ctcttctttt agctttgccc atagggattt ttgctggttt ttatcttgtg gaatatacaa
     5041 aaaaagattc cctttgtgtt aaaatcatgc gattggcctc agataccttg tctgggattc
     5101 cttccattgt ttttggtctg tttggcatgc tcttctttgt agtcttctta ggttttcaat
     5161 actctctgtt atcaggaatc ttaacctcag ttatcatggt gttgccagtc attattcgct
     5221 caacagaaga agccctttta tctgttagtg atagcatgcg tcaagcaagt tatggacttg
     5281 gggcaggtaa gttacggact gtttttagaa ttgttctacc agttgccatg ccaggtattt
     5341 tagctggagt gatactagct attggccgta tcgttggtga aacagctgcc ctcatgtata
     5401 cattaggtac ctctaccaat acgccaagta gtctcatgtc ttcaggccgt tctctagccc
     5461 tacatatgta tatgctgtca agtgaggggc tacatgtcaa tgaagcctat gctaccggcg
     5521 tgattttaat tattactgtt ttaatgataa atactctatc aagcttatta tctcggaaac
     5581 ttgtgaaagg agcttcctag tatgggaaca ttttcagtca gacacctaga cttattttac
     5641 ggggattttc aagccttaaa aaatatttcg attcaattac cagaaagaca gattactgcc
     5701 ttgataggcc catctggttg tggcaaatca acttttctaa aaacccttaa ccggatgaac
     5761 gatttggttc cttcttgcca tattgaaggc caagtcctct tagatgagca agatatttat
     5821 agtagcaaat tcaaccttaa tcagctacgt aagcgtgtag ggatggtttt tcaacagcct
     5881 aatccctttg ccatgtctat ctatgataac gtggcttatg gcccaaggac acatggtatt
     5941 cgagacaaaa aacaattaga tgccttagtg gagaaatctt taaaaggggc agccatttgg
     6001 gaagaagtca aagatgatct taaaaagagt gccatgtcct tatctggcgg tcagcagcaa
     6061 cgcctttgca ttgcgcgagc tttagcagta gaacctgata ttctgttaat ggatgagccg
     6121 acttcagcct tagaccctat ctccacttta aaaattgaag acctcattca gcaactaaaa
     6181 aaagattata cgattatcat tgttacccat aacatgcaac aagcttcacg tatttcagat
     6241 aaaactgctt ttttcttaac aggagaaatt tgcgaatttg gagataccgt tgacgtgttt
     6301 accaatccaa aagatcagcg cacagaagac tatatttcag gacggttcgg ataaggaagg
     6361 aaaaacctat gagaaatcaa tttgacttag aattgcatga attagaacaa tcctttttag
     6421 gactagggca acttgtcctt gaaacagctt caaaagcctt actggcctta gcctccaaag
     6481 acaaggagat ggcagagcta attatcaata aggatcatgc tatcaaccaa ggtcaaagcg
     6541 ctatcgaatt gacctgtgcc cgtttgttgg ccttgcagca gccacaagtg tctgaccttc
     6601 gatttgtgat tagcatcatg tcttcttgtt cagaccttga acgtatggga gaccatatgg
     6661 caggcattgc caaagctgtt ttgcaactaa aagaaaatca actagcccct gacgaagaac
     6721 agttacacca aatgggtaaa ttatccctca gcatgctatc cgatttattg gttgcctttc
     6781 ctttgcacca agcctcaaaa gctattagta ttgctcaaaa agatgaacag attgaccaat
     6841 attattatgc cttatcaaag gaaatcattg gacttatgaa agaccaagaa acctcaattc
     6901 ccaatggaac acaatacctt tatatcatag ggcatctgga acgcttcgct gattacattg
     6961 ctaacatttg tgaacgccta gtctacctag aaacaggaga actagtggat ttgaattaat
     7021 tcaactaatc cttaaaagag aagagtacga ttaagtgctc ttttttatgg ttgtaaaaaa
     7081 gttcatttga ccaatttaag cagtgtagat agtgaggagc tgtttcaatt ctatcgtgaa
     7141 cgagggaatg ctgaaaactt tatcaaagaa aggaaagcag gattctttgg ggataagaca
     7201 gatagttcga ccatgattaa gaatgaagta cgtatgatga tgggctgtct ggcttataat
     7261 ctctacctct ttttaaagca gctagctggt gatgaagtaa aggccttgac tatcaagcgt
     7321 tttcgacgtc tcttccttca tattgccgga aaatatgtct ctactgctag acgacatatt
     7381 ctcaaattct caagtctata tgcctattca aaacagtttc aagccttatt tgatacaatc
     7441 tgccagataa atctgatact ccctgttcca tatagagcta gagggcaggg gaaaacatgc
     7501 ctaacagaat aagtcacctt attttaaaaa tcgagcatca aaccaaggga ggagtctgcc
     7561 cttttttagg aaaaaatcaa gacaaatctc ctcaattatg tctctaacat cagaaattaa
     7621 gcaaaatcac cagaaggaca gtatttcaac tagcttttct ggtaattttt gaactgtgta
     7681 gttcgttagt gccagatatg aataatttgg gatgataaat ctttcttcct caggtagcct
     7741 atcataatac tcttcaaaaa tcttatcaaa acactctctt tcttttgggc gatagtttca
     7801 tcttcgtatg taggagtcct catcaagaaa tacttcaatt ctaggtattc cttatccaac
     7861 tctatataac ttggcatcaa cttgtaatcc tcaaccccca aacgttcagc gatatatttt
     7921 aactttgtta gtgttggtct ggattctcca ttttcaattc taattaattg acggatactt
     7981 aattcagact catcaccaca aaattctgaa cgactgattt ttttagccaa acgtaatctt
     8041 ttaatttttt cgccaaactc tcgcaaccta caagaacctc ctgagttgtt tacctctatt
     8101 ataagcatat actgaatcaa actatctatc agatttcttc tcactttaac taaagactaa
     8161 gagtttatcc cttcatctcg gtctttgtgt atttttccac cataccccag taatgcaagt
     8221 gcaaaatcct ctagaatatg atagaataat ggaaagaact ctatcaagga ggaaatcatg
     8281 gaaaaacaaa ccgtcgccgt cttggggcct ggttcttggg gaactgccct ttcacaagtc
     8341 ttaaatgaca atggacacga ggtacgtatt tggggaaatc ttcccgagca aatcaatgaa
     8401 attaatacct atcatactaa caagcactac tttaaagatg tcgttctaga tgaaaatatc
     8461 attgcctaca ccgacttagc agaaacattg aaagatgtgg atgcgatttt gtttgttgtc
     8521 ccaacaaaag tgacacgact tgttgcccaa caagttgcac aaaccttgga ccataaggct
     8581 atcatcatgc acgcttcaaa gggattagaa cctgatagcc ataaacgatt atcaactatc
     8641 cttgaagaag aaattcctga acagctccgc agtgatattg tcgttgtttc agggcctagt
     8701 catgcggaag aaaccattgt gcgtgaccta actttaatca ctgctgcttc taaagattta
     8761 caaacagctc aatacgttca ggagctattt agtaatcact acttccgact ttataccaat
     8821 acggatgtta tcggggttga aactgctggt gctcttaaaa atattattgc tgtcggtgct
     8881 ggagctttac atggtcttgg atttggtgat aatgctaagg cagccatcat cgctcgaggt
     8941 ttagcagaaa tcacccgcct aggggtagca ctcggggcca gtccattgac ctatagcggc
     9001 ttatctggtg tgggagattt gatcgtaacg ggaacttcca tccactctcg taactggaga
     9061 gctggagatg ctctcggacg aggagaatcc ctagctgata tagaagctaa tatgggcatg
     9121 gtaatcgaag gaatttcaac gactcgagca gcctatgaac tagcccaaga acttggagtc
     9181 tatatgccca ttacacaggc tatttaccaa gttatttatc acggaaccaa tatcaaagat
     9241 gccatttatg acatcatgaa caatgaattt aaagcagaaa atgagtggtc ttaaccctct
     9301 atagaaagga tttttatgac atcaaaagtt agaaaggcag tcatccctgc tgctggacta
     9361 ggaactcgat ttttaccagc aaccaaggcc cttgccaaag aaatgttgcc aatcgtagac
     9421 aaaccaacta tccagtttat cgtggaagag gctctcaaat caggtattga agatattcta
     9481 gttgtcactg gtaaatcaaa acgttctatt gaggaccact ttgattcaaa cttcgaattg
     9541 gaatataacc tcaaagaaaa agggaaaaca gatcttttga agctagttga tgaaacaact
     9601 ggcatgcgtc tgcattttat ccgccaaact catccacgcg gtctcggaga tgctgttttg
     9661 caagccaagg ctttcgtcgg aaatgaacct tttgtcgtta tgcttggtga tgacttgatg
     9721 gatatcacag acgaaaaggc tgttccactt accaaacaac tcatggatga ctacgagcgt
     9781 acccacgcgt ctactatcgc tgtcatgcca gtccctcatg acgaagtatc tgcttacggg
     9841 gttattgctc cgcaaggcga aggaaaagat ggtctttaca gtgttgaaac ctttgttgaa
     9901 aaaccagctc cagaggacgc tcctagcgac cttgctatta tcggacgcta cctcctcacg
     9961 cctgaaattt ttgagattct cgaaaagcaa gctccaggtg caggaaatga aattcagctg
    10021 acagatgcaa tcgacaccct caataaaaca caacgtgtat ttgctcgtga gttcaaaggg
    10081 gctcgttacg atgtcggaga caagtttggc ttcatgaaaa catccatcga ctacgccctc
    10141 aaacacccac aagtcaaaga tgatttgaag aattacctca tccaacttgg aaaagaattg
    10201 actgagaagg aataacaaaa tcatttatat aaagattagc cacacataaa ttaagtaaat
    10261 tctctacttg aatctaccta tttaataaaa actaatgaaa acgctatact tgtatttgtt
    10321 ttttcattaa aataagagta gaataaatta gtatagtaaa acaaaaaagc accgaatcgg
    10381 tgcgcacttt ttcaagttgt gtacggacaa agccttattt taactttgct atgttgtttc
    10441 gaatggttcc aaaataataa ataattttaa atttgactta actgttggag tagtcatggt
    10501 taaattaaat caaccgagcc gaacataagt tgtttaattt tgtggaagct attaataaaa
    10561 atataataag ggagaaagat aggtgtaatt ttaattttaa agtaattgcg gacactatca
    10621 aagtaaaaga ttatggagaa caaatttgta gaatttatcg aaaacaataa aaaagtaatc
    10681 atttcatcag ttgcagttgg tgttgtattg gtattagggt ttggatggta ttcatataac
    10741 caacaacaag cagaacaaca agcaaaaatt gtacaattag aaaaagatag caaatcagac
    10801 aaagaacaag ttgataaact atttgaatca tttgatgcat cttcagatga atctatttct
    10861 aaattaaaag aactatctga aacttcactt aaaaccgatg caggtaaaga ctatcttaat
    10921 aacaaagtca aagaatcatc taaagcaatt gtagattttc atttgcaaaa aggtttggct
    10981 tatgatgtta aagattcaga tgacaaattt aaagataaag caaccttaga aaataatgta
    11041 aaagaaatca ataaacaaat tgattttatc aagaaagttg atgaaacttt caaacaaaaa
    11101 aaattggatg aaactgtaaa atctcttaca gatattgcag acaaattcca aaaacaaatt
    11161 gatgttctga agaaagaaga agaacaaaaa gcatctgaca aagctaaaga agataagaag
    11221 aaagaagaat caacttcatc tcaatcttca aatagttcat ctcaagcatc aagcagttct
    11281 tttagttcat attctggtaa ttcagattat gctccagaac aaacatacac agctgataat
    11341 agccaatctt attcaggttc aactggtgga gacaatagta actataaagc accagctgct
    11401 acagacaacg gaggaaatga tggctatatt cttgggcacg taactggtgc agatggatcg
    11461 caaagagatt tttattttaa ccgttcaaac ggagatgttc gtgatacaag cggcaatcac
    11521 gtaggaaact ttggaggggg cattacagat tttagacaac gttaataact attttagggc
    11581 tgtgttgttt cgaatggttc caaaacacat taaaagctac tcatttttta agtagctttt
    11641 ttcttattca agtttacata ttagttgtca caaccccatt cccttgtaga aaagcaaaat
    11701 ggcgagtcct acgaacaaga ctaccgctcc taatctctgg ctggtattat acatccgttt
    11761 ttctcctcta actggaaaga taactgctag aaatgcgcca ccaactgcac caccgatatg
    11821 gcctgctagg ctgattcctg gaatcagaac acttccaata atgttaacca caaaaagtgt
    11881 cagataggat tgccctagct gttggatata aggattgcga gttgcatagc gaagaacaat
    11941 aatcgcggca aatagcccat aaagagaggt agaggcgcct gctgctaagg atttaggact
    12001 aaatacaaaa acaaagagat tgcccatcat tcctgataag agatagagaa aaaagaactg
    12061 cttagagccg aaaatctcct ctacctgcct tccaagataa taaagtgaaa gcatattaac
    12121 aatgaaatgt tcccacccaa tatgaacaaa aatggcagac aagagacgcc aaacctgctc
    12181 gggaaagagg cgaatagctg gcccatacat ggctccaaat cgaaataatg tatctgccct
    12241 gtcaaagttt ccgcctgcag tgaccaacat tagtaaaaat accaaggccg tcactaagag
    12301 gaagaaactc gtcacagggt aacgtctatc aaagatttcc ttcatcaatt aatacctcct
    12361 gaacaggaat atcatggttt tcaggtataa agtcctgaat ttgacaagga tatatcgtac
    12421 tcaaagtacg accagaaaaa tgttccaaat agcggtcata atagcctcca ccgtatccta
    12481 tccgatatcc tttcgtcgta aaagccagac caggaacatg aatcaaatca atctgagatg
    12541 catccaccac ttccacatct ccctgtggct ccagtaaggc aaaggcagtt tttaccaact
    12601 gttgcggatc atagaccaca aactccatgc gccccttggg ataagttttg ggtattaaaa
    12661 ccttcttgcc gtccttcagc gcctgctcaa tcagttcccg cgtttgaaac tcatgagaaa
    12721 aagagaggta ggttgcgatg accttggctt cttggtagaa gggatggtgt aaaagccgct
    12781 cggttaaagc ttggtctata gcctgttttt gctcttgaga tatagccttc atttcatgca
    12841 agacttgctt gcgtaattcc gatttcatag acaagccctc tattctgctg ccttcttttt
    12901 caggaaacta gacaccgcag ccaccccaat agctaagact tcttccttag gactcatttg
    12961 agggtgatga agagcgtagg gactatcgat acccagccaa aacatcacgc catcaacctt
    13021 tgaaaggaga taaccaaagt cctcgcctgt catagcaggt tcgatatcaa tcaactcgat
    13081 tccgtctttt tcgtcaaaga agtccatcag ttcacgcgcc aaggctggat tgttctcaac
    13141 aggtaggtat ccaccttgtt tgagttccac ttcgacttcc atatcaaagg cagctgcaac
    13201 cccttctgca actgttttta ccctcttttg caccaagaga ctcatgtcct gtgtcaaggc
    13261 acgaatagtt ccatgtaaaa aagctgtttc tgtgatgaca ttgttggtgg ttccagcttg
    13321 aaaaacgccg aaggtcacca ctgctccctc gattgggttg acattgcggc taacaactga
    13381 ctgcacttgg gtcacaaagt aactagccgc taccaaggcg tcattggctt catgaggaaa
    13441 agctgcgtgg ccacctttgc ctttgaaacg gatcttcacc tcgcaagttc ctacaaagag
    13501 tgtatgagta ttagtcgcaa tctggccgac tttcaaatct ggacgaacat ggagaccata
    13561 gaattggttt ggcaaccaat ctccaaaagc accgtcctca tacatgagca taccaccagc
    13621 ttcattttct tcagcaggct gaaatagaaa gagcagatta ttcttgggtt gctcctcaag
    13681 ggcgcgctca agacagccta aggcaatggt catatgaaaa tcatgaccac aggcatgcat
    13741 gcgaccttgg tgttgagaag caaaaggtag acctgtttgt tcgacgatag gcaggccatc
    13801 aatatctgtc cgccaaccaa tggttcgctc cggctgactt ccctgcaggt agaccaaaat
    13861 ccctgtccgc caagtacgaa tttgaacaaa atccttgccc gtagtcaatt tctcaatcac
    13921 atccagcaaa taagcctgag tcttgaactc ctccaagcca atctctggta tctggtgtaa
    13981 atctcgtcta gtctgaatca aatctaacat ctatctgtcc tccgatatag cagaaagagg
    14041 ctggaaaaag ggttccgcct cttttttact tttacaatta caaggtacga agcgcatcct
    14101 ctagcgctgt tttttgttgg gtttgggcat caatttcttt gatgatacga gctggaacac
    14161 ctgctactac cacgttttct gggacatctt gggtaacgat agctcctgca gcgacaactg
    14221 aaccactacc gatttggact ccttcgataa ccactgcatt agcaccgata agaacattgt
    14281 ctccgacacg gactggttca gcactagctg gctcaatcac acctgccaaa actgcacctg
    14341 caccaacgtg gctatttttt ccaacgatgg cacggccacc aaggatggca cccatgtcaa
    14401 tcatggttcc agcaccgatt tcagcaccga tattgataac agatcccatc atgataacag
    14461 cattgtcacc aatttccacc tggtcacgga taatagcacc tggctcgata cgagcgttga
    14521 tagcacgctt atctagcaaa ggaactgcag aattacgagc atcttgctcg acaacataat
    14581 cttgattttc taccaaacct tcaagaagcg gagccacgtc cttccagtct ccgaatagga
    14641 catttcctag tttgacaaca gagctaggca cagcagttgc gagttgcccc tcaaaggtta
    14701 ctttgacact ggttttcttt tcagcattgg cgataaattg gataatttct tgagcgttca
    14761 tttttgtagc agtcataggt gcctcctggt tcgttataat gatacctatt ctaccaaaaa
    14821 aggcctcaaa tttgaaacct ttttgtctgt ttttaggtat gattttttag ggatgtgaga
    14881 taaaacgtgc tgtcggtaaa agcaagcccc taccgataca acctaaaaac actcttcaca
    14941 actatctccc cgtgttttat tgactattct agtatagcac acttttagaa ttaagaaaag
    15001 actttttatc tactttcttt cgcttcttct atagacaaaa atatcatggg taaaataatc
    15061 aaggctatag ctagaaggag ggaccaatcc actactaatc ctaagaacaa aacactcaag
    15121 agagcagaag agagaggttc actggcactg ataacggcaa ccaccaaagg agaaaccaag
    15181 gacacagcct tcatggaaat gaaaaaagca aaagccgttc caaagaaagc gataatgagg
    15241 caaatcaaga tactccaaat atcaagagta aaggaaagct gataaaccgg cgagaggaca
    15301 ttgctaaaca aacctgccaa aatcatcccc cacccaaccg taggaacaaa accataacgc
    15361 ttagcaaaag gttggggcaa gataacatta aacataacac ccatggcact cagcaaacct
    15421 gttataagag ctagcggcgt catggataac tgagagagat ctccctttgt cgccatcaag
    15481 caaacaccca gcatggcaac caaaacatag aaaacagcgc tttttgacgc tcgtttttga
    15541 taaaccaagc gattgtaaaa gaggataaag acagggctaa taaactgtaa aatagttgct
    15601 gtcgtagcat ttgagtattc tacacagaga tagaaaaaat actggactga aaaaatcccc
    15661 aaaatagcat aggctaaaaa gggcaggtaa tttttcttgt ctcgccaaat atctagcact
    15721 tgcgatttta attgtattgc agaccaaatg agtacaatac tccctgccag tgtcaaacgc
    15781 atagaggtaa tccagcccga agacacctga taatgagtaa agaagtactc tcctaaaatt
    15841 ccacagattc cccatattaa gccggatagg agcgaataaa tttttccgtt aacaatcttt
    15901 ttctgatact gattcatacc cttattgtaa cacgaaagga aaaaagtggc aatccattga
    15961 ttggccactt catttagaga attatcgtct cgcccttgaa gaagaaggtc gtgtagtact
    16021 tgagttactg ctatcgctag aactactact tgaactgctg gagctggatg gagttggtag
    16081 actccccaca atactagacc aagcattctg ataatccgca tcacttccgc caatagcaaa
    16141 gcgataactt gtcgctggcg ctcctgactt attagcccaa tagctggtaa cagtcgaacc
    16201 tgtgacctct acctcttttc cttcaacaga aaccttccct ggtttttgac ctgttgattt
    16261 caagacttcc gatttcacta cactaggatc taaagcaaag cgctcgttcc cccaaatgct
    16321 tggggaagct tgctgaatcg catttactag atgagccatg taattagagt tattagaata
    16381 acctgctcta cgtgacaatg aatgattatc atcatgccca atccagccac ctagggttaa
    16441 tctaggtgtc gaaagcatga gccacatatt ttcgtcttgg ttggttgtac cagtcttccc
    16501 aatccaatct gcattagcca gagtaggatt taaagaagtc aggttagact tgaaggttgt
    16561 tgtcacacga gaggatagaa cttctcgtag caatccctgc ataatcgtcg cagtagcttt
    16621 tgaatagact tgaaccggtt tatcctgata ctcatacacc actctaccat ctgctgcttc
    16681 aatctttgaa atcacatgct tctgatgata aactccatta ttagctaagg tctgatagcc
    16741 attggtatgc tgggcaactg tgacttcaat accaccaccc attggcaagc tctcaatacc
    16801 gtactcagga atctcgtaac ccatcttttc catataaccc ttgacatcaa caccattttc
    16861 acggagcaga ctataggtcc agtaagcagg gatattccat gagtagttca gagcttctcc
    16921 caaggtcatc attcctgttc ccttgctatt agcatacata atcggattgc cattagcaaa
    16981 gtttgttgga tagttagata gaatcgtttc acttcccatc aagccctggt caatagcaat
    17041 accgtaggcc agcaagggct tggtagtaga agctggcgaa cgtttggtat caaaggcatg
    17101 attattttga ttttcttgat aattacgacc acctacaaag cctagaatag cacctgtttg
    17161 gttgtccatc aagacattcc ctacttctac acgacctgtt ccatcgtcta aaagatagcc
    17221 ataatcagca accgcacttt gcatggcaga atgaattttc tgatctatgg tagtagtaat
    17281 cttataacca ccattttcaa tttccttggc tgccaaatct cgataaaact tctgagttgc
    17341 ctcatttttc aactccttag cggagacatt gtctctctga gctagatagt catacatacg
    17401 ttcttgagct tctgccaaag ttgtaaagta taaatagtct cgtgaaattc ctgtaaccgt
    17461 gcccgatggt aaaaagtcct gtttaaggtc ataatccttg tactgagaat actcgtcttt
    17521 gcttaatgca cctgtacgat acatactgta aagaactgcc ttagcccgtc ttaagccaat
    17581 ttctaggtct tcatcactct tcaactcccc agtattttca taaggagagt aagtaatggg
    17641 actctgtgga agtcctgcta aaaatgctgc ttgaggaaca gtcaactgac tggcatctac
    17701 accgaaaatt ccctcagctg cttgccgagc ccctgcaata ttctgtccct tattatttcg
    17761 gccaaaggga gccacattga gataggtcgt taaaatctca tctttattca tggcgcgttc
    17821 caaggcaaga gcatccacaa tctctgccgc cttacgagcc aaggtcggcg catccccaac
    17881 cacctgctgt ttaattagtt gctgggtcaa ggttgaaccc ccactagagg aacccaaacc
    17941 tacaaatttc cccaaggtcg cacgaatcac cgccttgggt actacaccct tatgttcttt
    18001 aaagtgttca tcttctgtcg caatgatagc cttcttcaga ttttccgaaa tttgctcaga
    18061 tgagatagaa gtgcgcaaca aatcactctc tatggaagca atcaccgtcc cgtccgaata
    18121 ggtaatctct gaaatagaag agatgtcctt gacctgattc accaattctt ctgtctgagg
    18181 cacccgaacc ttgtcaaata aggccactcc gtaccccaaa gcaatcccag ctcccaacat
    18241 tcctcctaga aaaccgagta caaagagtaa gttaaataag gcttttatac tcagtaaaat
    18301 agctgggaaa atggctgact tatctaaggt tttagatttt ttggtacttg aacctttctt
    18361 gccaggtcta gctgattttt tatttttttg tttttgctgg aaaaattcca gcatttttcg
    18421 ttttaattca tttaattgat tttgcatgga tttcctcact ttatctatta taccacaaaa
    18481 gggaaatttt caataaaata gccactttct tccctattct gctaggctat tgcccaagtt
    18541 tgtgatacaa taggtagaaa caataatttt aaaaaggaga aaaaacacat gcacattttt
    18601 gatgagctaa aagagcgtgg tttgatattt caaacgactg atgaagaagc tttgcgtaaa
    18661 gccctagaag aaggtcaagt ttcttattat actggctacg atccaactgc tgacagcctt
    18721 cacctaggcc accttgtcgc aatcttgaca agtcgtcgct tgcaactagc aggtcacaaa
    18781 ccttatgcgc tcgttggcgg tgctacaggt ctcatcggag atccgtcctt caaagatgct
    18841 gaacgtagtc tccaaacaaa agacacagta gatggctggg tcaagtctat ccaaggacaa
    18901 ctttctcgtt ttcttgactt tgaaaatggc gaaaacaagg ctgtcatggt caacaactac
    18961 gactggtttg gcagcatcag cttcattgac ttcctccgtg atattggaaa atacttcacg
    19021 gtcaactaca tgatgagtaa ggaatctgta aaaaaacgaa tcgaaacagg aatttcttac
    19081 actgagttcg cttaccaaat catgcaaggg tacgacttct tcgtccttaa ccaagaccat
    19141 aatgtcactc ttcaaatcgg tggttctgac cagtggggaa atatgacagc tggtaccgaa
    19201 ttgcttcgtc gtaaagcgga caagactggt cacgttatca ctgttccact aatcacagat
    19261 gcaactggta agaaatttgg taaatcagaa ggaaatgccg tctggctcaa tcccgaaaag
    19321 acttctccat acgaaatgta ccaattctgg atgaacgtga tggacgctga cgctgttcgc
    19381 ttcttgaaaa tctttacttt cttgtcactt gatgagattg aagatattcg taaacaattt
    19441 gaagcagcgc cacacgaacg cttggctcaa aaagtcttgg ctcgtgaagt tgttacactt
    19501 gttcacggag aagaagccta caaagaagca cttaacatca ctgagcaact ctttgcagga
    19561 aacatcaaaa acctttctgt caaagagctc aaacaaggac ttcgtggtgt gccaaactac
    19621 caagtacagg cagacgaaaa caacaatatc gtggaactgc tcgtctcatc tggtatagtt
    19681 aactcaaaac gccaagcccg tgaagacgtc caaaacggag ccatctacgt aaacggcgac
    19741 cgcatccaag agcttgacta tgtcttgagt gacgctgata agttagagaa tgaactgact
    19801 gttatccgtc gtgggaagaa aaaatacttt gtattgactt actaaactat tcaacattta
    19861 tctataaaca aaggagttag cctcgagaaa ggtaactcct ttttgctgtt aataactctc
    19921 atctatctat ttttaataga caggctacgc aggacaatgc gcaaggttgt tagattatgt
    19981 aagatagaga gatttgaagg actgagccaa ttaaataagc cgaagccaat caaactacta
    20041 tttacgacaa cggtatcttg aatatttttc ttgatgagtg tttgcaaaga tgatgataac
    20101 gaatccaact cttggaagaa atccaaacga ttatctaaca ataagatatc actcatctgc
    20161 ttagaaatat ctgcactctc attcatcacc acaccgatat ctgatagagt taaagccgct
    20221 gagtcattca atccatctcc aaccatcaaa atagtgtgac ctgctttctg cagtttctct
    20281 actaactcaa atttcccatc aggtttcaag tctgtataga cctgatcaaa gggcaaatct
    20341 ttgactaatt cctctgtcct agtcaaggtg tctcctgttg ccagaatcaa ttttttcccc
    20401 tgtgccttaa gtttatccaa ggctgttttt gcttcttttc tcaaaggagt atgaatgcag
    20461 aacattccaa tcaattcatt ttgataagcc aagaataaga gattgtagtg actcttgtac
    20521 tcttcaatta aagcattttg ttctgaactg atatgaatct gctcatcctg catcaagaca
    20581 taattcccaa taagaactgg ttggccatct atatgagatt tgatcccctt gcttgcgata
    20641 tattggagtt tcccatgcat ttcctcatgt tcaattccct ctatctcagc ttgcttgacg
    20701 atggcattag caataggatg ataaatgtgt tcctcaagac aggcactgat tctgagaata
    20761 tcttcctcac tatagtctcc aaaaggtaac accttttcaa ctataggata actagttgtg
    20821 attgttcctg tcttatcaaa caagaaagta tcaacttcca gatatttctc cagaacatct
    20881 ccatccttaa tcaccatttc acggttcaac ccttccttga taactgtcaa ataagctaca
    20941 ggagtagaga ttttcaaagc gcaggagaaa tcgaccaata ggaaagaaat agccttagaa
    21001 aaagaacctg tcaataggta agtcagccca gaccccaaga aattatattt gacgacttta
    21061 tccgccatct tgatgaaata gcgttgtttc gttttcttgt tttcttcaga tttcttcatc
    21121 aactcaatca gctgtaaaat acggctgttc atctgattat ctgttacacg aatgcgtaac
    21181 tctccagttt ctaatactgt atttgcacaa accaaatcag actctctttt ttcaactgga
    21241 aaactctctc ctgtcaagga actttcgttg accataccta aacctgaaac tacttgtcca
    21301 tcaaacagaa tttcatttcc ttgagataag atcaagacat ctcctatttg aacatcggaa
    21361 ctcttgatac taacaaccgt atcgccctgt actaggaata catcgctctc ttttgcaaga
    21421 agactctgtt ctaaatctgt tgcagttttt ttcaaggacc actgatctaa atgattcccc
    21481 aaatcaagca taaacatgat attgctagct gtcttggatt ggttcataaa caaggacaat
    21541 aaaatagccg aacagtccaa gacttccatc gttagttcct tacgcgctag tgtttgatag
    21601 gcttctctaa tataacccaa agcctgataa caagtccata tatagcgaat aggatacggc
    21661 acaaaactac gaaaaagtac acgcttaacc gctgcacctg aaacaataga ataagcactc
    21721 tcttctctac gaatgggaag agtcatcaac tcagaaactt tccctttatc aattcttttt
    21781 aaaaaggctt ctgcattatc taatacagaa aagccttctt ttatgcgtag agtaaagtgc
    21841 tgttgatcca tgtaaaactg gatagactca atcccctttt catctctcgc caaggaacga
    21901 agatagtctt gaatatccaa ggtaagtgaa aaagaagatg atagtcggat atgttggtat
    21961 cctctatgta gcactttaaa agacatatta ttcacctata aggctatcta attgctcttc
    22021 ttttttctct tgctcgtaca aatatttggc atcttgcaag acatcgtctc catgttgctt
    22081 cacaacagaa acagatgcat ctagctcgtc tttcaacttg taagccttag ccaaagcttt
    22141 agaataacct tttttagctt ccttacttgc taagattttc aaaccaaggg taccaaatgc
    22201 gacaccaccc aaaaataatg aagatttttt cgcaactttt gcaacggtta atacttcttt
    22261 taacatactt atttcctcct tatcattatt atatagcaat ttagatataa aagcaatttc
    22321 attctataaa ttggagaatt agttttattt ctactgaatc tcccatctac ttattcctaa
    22381 agttgctttc atttgcctct tttgatacac ttaaactatg aatacaaatc tcaagcccaa
    22441 acttcagcgt tttgcttctg cgactgcctt tgcctgtcct atctgtcaag aaaatctgac
    22501 tctgttagag actaatttca agtgctgcaa ccgtcattct tttgacttgg cgaaatttgg
    22561 ctatgtcaat ctagcacctc aaatcaagca atctgctaac tatgacaagg aaaattttca
    22621 aaaccgtcaa caaatcctag aagccggctt ttaccaagct atcttagatg ctgtatctga
    22681 cttgcttgca agctcaaaaa ctaccacaac aattttggat atcggttgtg gtgaaggatt
    22741 ctattctcgc aaactacaag aaagtcactc tgaaaaaact ttctatgcct ttgacatctc
    22801 caaagattca gtccaaatcg ctgctaaaag tgaacccaac tgggcagtca attggttcgt
    22861 tggcgacttg gcacgacttc ctataaaaga cgctaacatg gatattctgc ttgatatctt
    22921 ctcacctgcc aactatggag aatttcgtcg cgttttatcc aaagacggta tcttgataaa
    22981 ggttatccca actgaaaatc acctcaaaga aatccgtcaa agagtacagg accagctgac
    23041 aaacaaggag tattctaacc aagatatcaa ggagcatttc caggaacact ttaccatcct
    23101 atctagtcaa actgcctctc tgactaagac tatcacagca gaacaactcc aagccctact
    23161 cagtatgact cctctcctct ttcacgttga ccagagcaag attgactgga gccaactgac
    23221 agagattacc atcgaagcag agattttggt tgggaaagca ttctaaacta gacttcccaa
    23281 aggtataaaa cttaccgaaa atcttcaata ttataaaaac gcataagaac aggtacacaa
    23341 accttaatct tatgcgtttt gttatagttt ccatacacat taaggggaaa tagttgaaat
    23401 cagttctctt aataaccatt gaataccata tactacattt accccaaata tgatataggc
    23461 cgtataaatc aagtatttcg atttttcccg cctcaaagaa tagatcttat acaaaataaa
    23521 taaatttaaa ataataaata atagagacaa aatcttcctc caaaatcaat attaaaagta
    23581 gccagtcaat catagttcta atctttattt tcgattcgaa attacaaact tatcaatgaa
    23641 caataagtga tataaggcca gtaccagacc ccaaacgcta ccacgaaaag agaattcttg
    23701 atgattgaga gtaaacaaat catggttacc aatatagagg caggtcaaaa taacaaataa
    23761 aatccaaaat aaatccgtcc atttatattt tgaaaaatat ttttttaaca taatagcata
    23821 tttttttgac tataataaca gtatatgata aaatgtaagc agatacaaat aaaaaggaga
    23881 aaagctcatg aacaaattaa tgaaatttat ttcggttttt ttgacgtcaa ttgtgttaat
    23941 tgtatcagcg attccaagtg tttcagctgt atacgcttct gaacaagtat cacaaattga
    24001 aacaaatatg gaacttcaac ctgtcacttc tctaacagaa gaacaaatca atacacttgc
    24061 aaacgaaatc caatcttttc atccagacgt ctcacaacaa tggatcaaag aagtaattaa
    24121 ccgacaatta caaggcgatt atacaatccc acctacatac tctccattta gagcagcttg
    24181 gcaaggtatt acagttaatc aaatgggtgc tctattagat actgcaatag ctttagcatt
    24241 aggaggaact actgcaggcc ttgcaaatct aattaaagta aaaggaaaac atgcagcaaa
    24301 aagtgctatt cgttcagcaa tttctagata tctaggtagt tggtttgtaa atgatgttgc
    24361 tttagaattc gctatgaatt tattatcacc ggggacttat ttagcacaat tatgggataa
    24421 aaatgatgcc attcctaaca acggaaggat taacttttaa tcatgagata tacaataaaa
    24481 ttaattgggt ataacgtatt ttcgttgttt atattcttta tcttatcaat gttgtttaaa
    24541 gttcccttta ggtggtggat cagcattgca atgacgactt cgtcgtacat tgtatataat
    24601 tacttaaaga aaaagagaga aaaggaatga tcttatacca gatcattcct tttctgcttt
    24661 ctgtaaatcc ctcggagtgt gtttggcgct ttgatacgaa gtgtcaaagc tgtataaacg
    24721 ttactatttc caaaaaagta acagaaaatt cctgctttgt aggactgctt tgggtgagta
    24781 atagacatgt cgactcaccc tatctcctga tggcgaaaag aatttagcaa tggtgcaagt
    24841 tgttctgaac tcgagaaaaa acatgccgaa atcgaagaaa agcgtgcaga acttgaagcg
    24901 aagaagcaag aaatgttgaa tcgcttggat aaatagaatt tagaaaacag aaaaactaaa
    24961 aagaatgtag ggtttatttc cctacattct taaaataact tagtacataa atgacaatgc
    25021 tgccactgcc gtcaatattg caaaaactat tttccaaatt tttttatttt ttccaaaaat
    25081 cttatcaggt aacaagctta ttacaagaaa ggtaataaac aacaccaatt taagtgtgta
    25141 tatcataaaa acaccttctt tcctacaatt atattataat actttatgta agcgaataca
    25201 agagatgtga ggtaaccaac tacgaaaaaa tataaggctg aagacagtaa aaaccagcat
    25261 ttaaagcctt cactgtatct aggatttccc tatttttaga caagattgac ccaaatccac
    25321 agcatttaaa aaagcgaatt tcaatcgaaa ctcgcttttt tacaaaatgt attagtataa
    25381 atttgtatct tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc
    25441 tcaaagcacc gctttgaggt tgcagataaa gctgacgtgg tttgaagaga ttttcgaaga
    25501 gtattagttc aagtgccaga tgtcttcatt atactgagcg attgtacggt cagatgagaa
    25561 gaatcctgct ttagaaatgt taacgatgac tttatccaac catgcgtcac ggtcttcgta
    25621 gtcagcaagc atttgctctt tgactttgat gtagtcttcc aagtcaagaa gagtcatgaa
    25681 ccagtctttg ttgatcaatt cattgtaaag acgttccaag cgctctttgt ttccagctgc
    25741 aagaactgca tcactaacga tgaagtcaac caatggtttg atagcttcac gagcgtagaa
    25801 ttcgcttgat ttgtaagctg cttttgcgta aaggtcgata acagtttctg aatcttcacc
    25861 gaagatgtag atgttttctt ctccaaccaa ctcagcgatt tccacgttag caccgtccat
    25921 agtaccaagt gtcaaagctc cgttcaacat gaatttcatg ttaccagtac ctgaagcttc
    25981 tttagaagca agtgaaattt gttctgagat atcacatgct gggataagga aacttgctgc
    26041 agtaacgttg tagttttcaa ccataactac ttgcaagtgt ggagctactg ctggatcgtt
    26101 agcaataact tctgacatgc aaaggattaa atggataatg tcttgagcga ttgtgtaggc
    26161 tggagctgct ttaccaccaa agaagattgt gattggacga gcagggatgt taccagcttt
    26221 gatgtcaagg tatttgtgga tcacgtacaa agcgttcatt tgttggcgtt tgtactcgtg
    26281 aagacgtttg atttggatat caaagataga atttgaattg atttccacac cttggtgttc
    26341 tttcaagtga cgagccaatt tacgtttgtt gtgagccttg atgctttcca atttttcttt
    26401 gacagctgct ttgtcttcat aagacaaaag tttttcaagc tcatctgctt catggtgcca
    26461 accatctcca agaatctcat ctaagtagtg agacaatctt gggttagcat gcataagcca
    26521 acgacggaaa gtgataccgt ttgttttgtt gttgaacttt tctgggtaaa ggtcgtagaa
    26581 ggctttcaac tcagaatttt tcaagatttc agtatggagt gctgcaaccc cgttaacact
    26641 gtatccgtag tggatatcca tgtgagccat gtgaacacgt ccgctctcat cgatgatttg
    26701 aacagctgga tctttgtact ctgccttcac acgacggtcc aattcttcga tgattggtac
    26761 caagtgagga accacttctt gcaagaattc aagaggccat ttttcaagcg cttcagcaag
    26821 gattgtgtgg ttagtgtagg cagtcatgct acgaacaatt gagattgctt cgtcaagctc
    26881 gataccacgt gcagttaaaa gacgaatcaa ttcaggaatc accattgatg ggtgagtatc
    26941 gttgatttgg acaactgcgt agtcagcaag gtcatgcaag ttgcttcctt tttcgattgc
    27001 ttcgtcgatg atcaattgcg caccgtttga aaccatgaag tattgttgga agatacggag
    27061 caattcacct tgacggtcac tatcatctgg gtaaaggaag agagtcaagt tgcgagcgat
    27121 atctgtcttg tcaaagttga taccatcttt aataatagaa gaatcaactg aatccaagtc
    27181 aaacaaacgc aagcggtttt tagtcgctgt ttcataacca gtaacatcaa tatcgtaaag
    27241 agttgatgtc aaagtaaagt ctgcaaatgg tacttggtag ctacggcttg agcaaaccaa
    27301 ccagttttgc tctgtcaacc atgcatttgg aattgtttct tgttggttgt ttttaagaac
    27361 ttgttggaaa agaccaaagt ggtagttaag accaacaccg tcaccattca aaccaagagt
    27421 agcaattgag tcgataaagc aggcagccaa acgtcccaaa ccaccattac caagagatgg
    27481 ttccaattca acttcttcaa cttcgatcaa gtctttacct gcagctgcaa gttctttttt
    27541 aacatcgtcg taaagaccaa ggttaatcaa gttgtttgac aagagtttac caatcaagaa
    27601 ctcagctgag atgtagtaaa cttttttctt accagtgttg actggttttt ggctgcttgc
    27661 aagcttgctg tagttaagaa gagcaaggta aagctcttca ttgctacatt ctgcaatggt
    27721 tttattgtaa cgattttgta caaattcttg tagtgataac atgtttagtt gtctcctgat
    27781 tattgtctta tttctttaaa tctaccaaat tttcattaat tcggcgataa attgttgtca
    27841 agtcaagcaa accttcctcg acagctggtg tcaattgatc ttcagtcata cgccaagacc
    27901 agtttccacc aagggtagat gggaagttca tacgagctgc ctcatccaat tctagtaaat
    27961 cttgcatagt cgcaattgcc ataaagctaa ctgatgaaaa tactgtacga agcatagcgt
    28021 gtaccactgt ttcgtattct ttacggttcg tgtaacgagc catgtactca cgagtcgcat
    28081 catcaatctc attacggtac caaccaagaa ccgtattgtt atcgtgtgtt cctgtgtaca
    28141 taactgagtt agcaggtgcc aagtgtgggc tatcaatgct ttcgtcttct gggttgaagg
    28201 caaattgaag aatcttcatt cctgggaagc cagtacgttc acgcaattcg atcacttcat
    28261 ctgtcatgaa gccaaggtct tctgcgatga tgtttagctc accaagttct tccttaacgg
    28321 ctgcaaaaag cttgtagcct ggacctttca cccactcacc aggtgctgct gtatcggaac
    28381 cagcagggat ttcccaataa gattcgaagc cacggaagtg gtcgatacga acgatatcgt
    28441 agattttgaa gctttcacgc aagcgttcaa tccaccattt gtagccgtct ttgtccattg
    28501 cttcccagtc atagattggg ttaccccaaa gctgaccagt tacagaaaac tcatctggtg
    28561 gacatcctgc gatacaagta gccttaccat tgacatctgt tttgaagaga tgtggatttg
    28621 cccacatatc acttgaatct tccgctacgt agattggcat gtccccaacg atttcgatgt
    28681 ggttgtcgtt agcgtaagct ttcaatttca accattgttg gaagaagaag tattgagtca
    28741 cacggtggta aaccaacttg tctgccaatt gctcacgata gctttcaagt gctgaagctt
    28801 tacgagcacg agcatctgca tctggccatt cagtccaagc aagattgtca aaatgctctt
    28861 tgatagccat atactcagca aagagctcaa gccatgattg gttgtcttga gcaaatttct
    28921 caaaatcttt aacatatccg acttcaaaga aacgcttcac cgctttttct aaaagaggac
    28981 gacgtgcata gtagatttta gcatagtcaa cttcagacgc atcgctacca aagtcaactc
    29041 cttcaaggtc acttgcttcc aacaaacctt gctccaccaa gatatctaaa tcgataaaat
    29101 gagtgtttcc tgcgaaggct gagaaagatt ggtaaggaga atccccgtaa ctagttgctc
    29161 ctaatggaag gatttgccag taacgttgtt ttgtacggac caagaaatca acgaagtcgt
    29221 aagcactttg accaaatgat ccgattccgt aagctcctgg aagagaagag atgtgcatca
    29281 acacaccact ttgacgtttt ttcataatag cacctcgtgt gttaaaataa tggaacgttg
    29341 cgtatttttc agacgcaaac gtttgcgtta cttataagta tactcctttt caagcataat
    29401 tgcaagcgtt tttaaaaaac ttttttgatt atttttaagg agactaactc attttagcaa
    29461 agataactta aaactatcta atcctaaggt ttgactctca cgagacagta tacaaagtac
    29521 aaaacctcct tagggagctt gaatttatat gcaacaaagc acaaacgtct atagaaaata
    29581 gatatagatt agaaataggg aggtagcccc tcctgatttc cctctttaga cagattccat
    29641 atatttttat taaaaatact gtattcttat ctatttcata cttttcttct attaaaatgc
    29701 aaaattatgc tatcaaatca agcttaaaaa ttttttaaaa tttttacaaa aaatacttgc
    29761 aaccgttttc tatttatgct atactaagct cataaaggaa aacgtttgcg tttccttatc
    29821 aataaaactt gctattcttt gggaggaata cactatgtca tctaaattta tgaagagcac
    29881 tgcggtgctt ggaactgtta cacttgctag cttgctcttg gtagcttgcg gaagcaaaac
    29941 tgctgataag cctgctgatt ctggttcatc tgaagtcaaa gaactcactg tatatgtaga
    30001 cgagggatat aagagctata ttgaagaggt tgctaaagct tatgaaaaag aagctggagt
    30061 aaaaatcact cttaaaactg gtgatgctct aggaggtctt gataaacttt ctcttgacaa
    30121 ccaatctggt aatgtccctg atgttatgat ggctccatac gaccgtgtag gtagccttgg
    30181 ttctgacgga caactttcag aagtgaaatt gagcgatggt gctaaaacag acgacacaac
    30241 taaatctctt gtaacagctg ctaatggtaa agtttacggt gctcctgccg ttatcgagtc
    30301 acttgttatg tactacaaca aagacttggt gaaagatgct ccaaaaacat ttgctgactt
    30361 ggaaaacctt gctaaagata gcaaatacgc attcgctggt gaagatggta aaactactgc
    30421 cttcctagct gactggacaa acttctacta tacatatgga cttcttgccg gtaacggtgc
    30481 ttacgtcttt ggccaaaacg gtaaagacgc taaagacatc ggtcttgcaa acgacggttc
    30541 tatcgcaggt atcaactacg ctaaatcttg gtacgaaaaa tggcctaaag gtatgcaaga
    30601 tacagaaggt gctggaaact taatccaaac tcaattccaa gaaggtaaaa cagctgctat
    30661 catcgacgga ccttggaaag ctcaagcctt taaagatgct aaagtaaact acggagttgc
    30721 aactatccca actcttccaa atggaaaaga atatgctgca ttcggtggtg gtaaagcttg
    30781 ggtcattcct caagccgtta agaaccttga agcttctcaa aaatttgtag acttccttgt
    30841 tgcaactgaa caacaaaaag tattatatga taagactaac gaaatcccag ctaatactga
    30901 ggctcgttca tacgctgaag gtaaaaacga tgagttgaca acagctgtta tcaaacagtt
    30961 caagaacact caaccactgc caaacatctc tcaaatgtct gcagtttggg atccagcgaa
    31021 aaatatgctc tttgatgctg taagtggtca aaaagatgct aaaacagctg ctaacgatgc
    31081 tgtaacattg atcaaagaaa caatcaaaca aaaatttggt gaataaaaaa tttgttcaag
    31141 gggggtggaa atcaaatccc cctttgaatt tatcaataga gacacaaata atttagcttt
    31201 cttataaaaa agtagtatcc tatgaaagga gttaatatgg aaaagcaaca acctagtaaa
    31261 gcagccctgc tgtctatcat tcctgggtta ggacagattt acaataaaca aaaagccaaa
    31321 ggttttatct tccttggtgt aaccatcgta tttgtccttt acttcctagc acttgcaacc
    31381 cctgaattga gcaacctcat cactcttggt gacaaaccag gtcgtgataa ttccctcttt
    31441 atgctgattc gtggtgcctt ccatctaatc tttgtaatcg tttatgtact cttttatttc
    31501 tcaaatatca aagatgcaca tacgattgca aaacgcatta acaatggaat tccagttcca
    31561 cgcacactca aagacatgat caaagggatt tatgaaaatg gcttccctta cctcttgatc
    31621 attccatctt atgttgccat gaccttcgcg attatcttcc cagttatcgt aaccttgatg
    31681 atcgccttta ccaactacga cttccaacac ttgccaccaa acaagttgtt ggactgggtt
    31741 ggtttgacca actttacaaa catttggagc ttgagtacct tccgttctgc ctttggttct
    31801 gttctttctt ggactatcat ttgggctttg gcagcttcta ctttacaaat cgtaattggt
    31861 atcttcacag ctatcattgc caaccaacca tttatcaaag gaaaacgtat ctttggtgtt
    31921 attttccttc ttccttgggc tgtcccagcc ttcatcacta tcttgacatt ctcaaacatg
    31981 tttaacgata gtgtcggtgc tatcaacact caagtattgc caatcttggc taaattcctt
    32041 cctttccttg atggagctct tattccttgg aaaacagacc caacttggac taagattgcc
    32101 ttgattatga tgcaaggttg gctcggattc ccatacatct acgttttgac tttgggtatc
    32161 ttgcaatcta ttcctaacga cctttacgaa gcagcttata ttgacggtgc caacgcttgg
    32221 caaaaattcc gcaacatcac tttcccaatg attttggctg ttgcggcacc tactttgatt
    32281 agccaataca ccttcaactt taacaacttc tctatcatgt acctcttcaa tggtggagga
    32341 cctggtagtg tcggaggtgg agctggttca accgatatct tgatctcatg gatctaccgt
    32401 ttgacaacag gtacatctcc tcaatactca atggcggcag ctgttacctt gattatctct
    32461 atcattgtca tctcaatctc tatgatcgca ttcaagaaac tacacgcatt tgatatggag
    32521 gacgtctaag atgaataact caattaaact caaacgtaga ctgactcaaa gccttactta
    32581 cctttacctg attggtctat caattgtaat tatctatcca ctgttgatta ccattatgtc
    32641 agcctttaaa gcaggtaacg tctcagcctt taaactagat actaatatcg acctcaattt
    32701 tgataacttt aaaggcctct tcactgaaac cttgtacggt acttggtacc tcaacacttt
    32761 gattatcgcc ttaattacca tggctgttca aacaagtatc atcgtacttg ctggttatgc
    32821 ttacagccgt tacaacttct tggctcgtaa acaaagtttg gtcttcttct tgatcatcca
    32881 aatggtgcca actatggccg ctttgacagc cttcttcgtt atggcgctta tgttgaacgc
    32941 ccttaaccac aactggttcc tcatcttcct ctacgttggt ggtggtatcc cgatgaatgc
    33001 ttggctcatg aaaggctact tcgatacagt gccaatgtct ttagacgaat ctgcaaaact
    33061 agacggtgca ggacacttcc gccgcttctg gcaaattgtt ctaccacttg ttcgcccaat
    33121 ggttgccgta caagctctct gggccttcat gggacctttc ggggactaca tcctctctag
    33181 tttcttgctt cgtgagaaag aatactttac tgttgccgta ggtctccaaa ccttcgttaa
    33241 caatgcgaaa aacttgaaga ttgcctactt ctcagcaggt gctatcctca tcgcccttcc
    33301 aatctgtatt ctcttcttct tcctacaaaa gaactttgtt tcaggactta caagtggtgg
    33361 cgacaaggga taatttatcc ccgccaccct ttttcatttt atactcttcg aaaatctctt
    33421 caaaccacgt cagctttatc tccaacctca aagttgtgct ttgagcaacc tgtggctagt
    33481 ttgcactttg attttcattg attattagca attgtcactg taaataatat ccttgtagca
    33541 agcaattttt ctcctagact tgaaataaag cgcatttctc tatataataa tactcatata
    33601 gaaaacacct tttagaaaga tacctatgct tccatatcca ttttcctatt tttcaagtat
    33661 ttgggggttt cgtaagcccc tgtccaaacg tttcgagctc aactggtttc aacttctctt
    33721 taccagtatc ttccttatca gcttgtctat ggtacccatt gctatccaaa acagctccca
    33781 ggagacctat ccgctagaaa cttttatcga taatgtctat gaacctctga caaatgaggt
    33841 tgtccaggat ctctctgaac atgctacaat tgtcgatggc acattaactt atactggaac
    33901 agctagtcaa accccttctg ttgtgattgg tccaagtcaa atcaaggaat tacctaagga
    33961 cttgcaactg catttcgata caaatgagct agtcatcagc aaggaaagca aggagctgac
    34021 ccgcatctct taccgagcca ttcagactga gagtttcaaa agcaaagaca gcttgaccca
    34081 agcaatttct aaagactggt accaacaaaa tcgtgtctat atcagcctct tcctagttct
    34141 cggtgcgagc ttcctctttg gtttgaattt ctttatcgtc tctctaggag ctagtcttct
    34201 cctttatatc actaagaaat cacgcctctt ttcatttaga acctttaaag agtgctatca
    34261 ctttatcttg aactgtttag gattgccgac tctgattaca cttattttgg gattatttgg
    34321 ccaaaatatg acaaccctga ttactgtaca aaatattctt tttgttctgt atctggtcac
    34381 tatcttttat aaaacacatt tccgtgatcc aaattaccat aaataggaga tttttatgcc
    34441 cgttacgatt aaagacgtgg ccaaggctgc tggtgtttcg ccttcaaccg taacccgtgt
    34501 tattcaaaat aaatcaacca ttagcgacga aacaaaaaaa cgcgttcgca aagctatgaa
    34561 ggaactcaac taccacccaa acctcaacgc tcgtagcttg gtaagcagct atactcaggt
    34621 tatcggatta gttcttcctg atgactcaga cgccttctac cagaatcctt tctttccatc
    34681 ggttctacgt ggcatctctc aagtcgcatc tgaaaaccac tatgccattc agatagcaac
    34741 agggaaagat gagaaggagc gtctcaacgc tatttcacaa atggtctacg gcaagcgtgt
    34801 agatgggcta atctttctct atgcccaaga agaagaccct cttgtaaaac tcgtcgcaga
    34861 agaacagttc cccttcctta tcttaggtaa atctctatct cctttcatcc cacttgtcga
    34921 caacggcaat gttcaagctg gttttgatgc gactgaatat ttcatcaaaa aaggctgcaa
    34981 acgcattgcc tttatcggag gaagtaaaaa gctcttcgtg accaaagacc gtttaacagg
    35041 ctatgaacag gcgcttaaac attacaaact taccactgac aacaatcgca tctactttgc
    35101 cgacgagttt ctggaagaaa agggctataa atttagcaag cgattattca agcacgatcc
    35161 acaaattgat gctatcatca caaccgatag cctcctagct gaaggtgttt gtaactatat
    35221 tgccaaacac cagctggatg tccctgttct cagctttgac tcggttaatc ccaagctcaa
    35281 cttggcagcc tatgtcgata tcaatagttt agagcttggt cgtgtttccc ttgaaactat
    35341 tctccagatt attaatgata ataaaaacaa taaacaaatt tgttaccgtc aattgatcgc
    35401 ccacaaaatt atcgaaaaat aagagactgg gcaaagagtc gttaaaagca aaaacgcata
    35461 ctatcaggta ttgaaaaaac ttgatactat gcgtttta
//
LOCUS       DAVBOU010000018        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBOU010000018 DAVBOU010000000
VERSION     DAVBOU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.018"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ879_000959"
     CDS             complement(21..833)
                     /locus_tag="VQ879_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3143127.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ879_000960"
     CDS             1023..2441
                     /locus_tag="VQ879_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3143128.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ879_000961"
     CDS             2494..3201
                     /locus_tag="VQ879_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143129.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ879_000962"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ879_000962"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3143130.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ879_000963"
     CDS             4279..5601
                     /locus_tag="VQ879_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3143131.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ879_000964"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ879_000964"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3143132.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ879_000965"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ879_000965"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3143133.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ879_000966"
     CDS             complement(7036..7353)
                     /locus_tag="VQ879_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3143134.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ879_000967"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ879_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3143135.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ879_000968"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ879_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3143136.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ879_000969"
     CDS             complement(8829..9251)
                     /locus_tag="VQ879_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3143137.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ879_000970"
     CDS             9398..9574
                     /locus_tag="VQ879_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143138.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ879_000971"
     CDS             9976..12189
                     /locus_tag="VQ879_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3143139.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ879_000972"
     CDS             complement(12411..12887)
                     /locus_tag="VQ879_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3143140.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ879_000973"
     CDS             13110..16313
                     /locus_tag="VQ879_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3143141.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ879_000974"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ879_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ879_000975"
     CDS             complement(17456..18085)
                     /locus_tag="VQ879_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3143142.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ879_000976"
     CDS             complement(18095..19096)
                     /locus_tag="VQ879_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3143143.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ879_000977"
     CDS             complement(19127..19768)
                     /locus_tag="VQ879_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3143144.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ879_000978"
     CDS             complement(19787..20602)
                     /locus_tag="VQ879_000978"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3143145.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ879_000979"
     CDS             20873..21307
                     /locus_tag="VQ879_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3143146.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ879_000980"
     CDS             21319..22509
                     /locus_tag="VQ879_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3143147.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ879_000981"
     CDS             22520..23011
                     /locus_tag="VQ879_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3143148.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ879_000982"
     CDS             23026..23805
                     /locus_tag="VQ879_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3143149.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ879_000983"
     CDS             23792..24610
                     /locus_tag="VQ879_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3143150.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ879_000984"
     CDS             24610..24903
                     /locus_tag="VQ879_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3143151.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ879_000985"
     CDS             24925..26826
                     /locus_tag="VQ879_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3143152.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ879_000986"
     CDS             26886..27887
                     /locus_tag="VQ879_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3143153.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ879_000987"
     CDS             complement(27997..28332)
                     /locus_tag="VQ879_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143154.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ879_000988"
     CDS             complement(28343..28585)
                     /locus_tag="VQ879_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143155.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ879_000989"
     CDS             complement(28596..29138)
                     /locus_tag="VQ879_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3143156.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ879_000990"
     CDS             complement(29154..29348)
                     /locus_tag="VQ879_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143157.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ879_000991"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ879_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3143158.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ879_000992"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ879_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3143159.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ879_000993"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ879_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3143160.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ879_000994"
     CDS             33051..34031
                     /locus_tag="VQ879_000994"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3143161.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6070 c         7607 g        10141 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBOU010000019        34102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBOU010000019 DAVBOU010000000
VERSION     DAVBOU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.019"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ879_000995"
     CDS             85..366
                     /locus_tag="VQ879_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3143162.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ879_000996"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ879_000996"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3143163.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ879_000997"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ879_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ879_000998"
     CDS             3042..3782
                     /locus_tag="VQ879_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3143164.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ879_000999"
     CDS             complement(3811..4266)
                     /locus_tag="VQ879_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3143165.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ879_001000"
     CDS             complement(4286..5461)
                     /locus_tag="VQ879_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3143166.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ879_001001"
     CDS             complement(5520..6365)
                     /locus_tag="VQ879_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3143167.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ879_001002"
     CDS             6490..7047
                     /locus_tag="VQ879_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3143168.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ879_001003"
     CDS             7066..7533
                     /locus_tag="VQ879_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3143169.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ879_001004"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ879_001004"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3143170.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ879_001005"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ879_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3143171.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ879_001006"
     CDS             9094..9342
                     /locus_tag="VQ879_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3143172.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ879_001007"
     CDS             9443..10603
                     /locus_tag="VQ879_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3143173.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
     gene            10871..11740
                     /locus_tag="VQ879_001008"
     CDS             10871..11740
                     /locus_tag="VQ879_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3143174.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11744..12700
                     /locus_tag="VQ879_001009"
     CDS             11744..12700
                     /locus_tag="VQ879_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3143175.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12700..13464
                     /locus_tag="VQ879_001010"
     CDS             12700..13464
                     /locus_tag="VQ879_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143176.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13464..14174
                     /locus_tag="VQ879_001011"
     CDS             13464..14174
                     /locus_tag="VQ879_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143177.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14482..15138
                     /locus_tag="VQ879_001012"
     CDS             14482..15138
                     /locus_tag="VQ879_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3143178.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15246..16341
                     /gene="prfB"
                     /locus_tag="VQ879_001013"
     CDS             join(15246..15317,15319..16341)
                     /gene="prfB"
                     /locus_tag="VQ879_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3143179.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ879_001014"
     CDS             16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ879_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3143180.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17044..17970
                     /locus_tag="VQ879_001015"
     CDS             17044..17970
                     /locus_tag="VQ879_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143181.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18256..20436
                     /locus_tag="VQ879_001016"
     CDS             18256..20436
                     /locus_tag="VQ879_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3143182.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20488..21303
                     /locus_tag="VQ879_001017"
     CDS             20488..21303
                     /locus_tag="VQ879_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3143183.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21443..22786
                     /locus_tag="VQ879_001018"
     CDS             21443..22786
                     /locus_tag="VQ879_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3143184.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23163..24353
                     /locus_tag="VQ879_001019"
     CDS             23163..24353
                     /locus_tag="VQ879_001019"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3143185.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24906..25841
                     /locus_tag="VQ879_001020"
     CDS             24906..25841
                     /locus_tag="VQ879_001020"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3143186.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25875..26912
                     /locus_tag="VQ879_001021"
     CDS             25875..26912
                     /locus_tag="VQ879_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3143187.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27085..27690
                     /locus_tag="VQ879_001022"
     CDS             27085..27690
                     /locus_tag="VQ879_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3143188.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27846..28376
                     /locus_tag="VQ879_001023"
     CDS             27846..28376
                     /locus_tag="VQ879_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3143189.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ879_001024"
     CDS             28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ879_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3143190.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            29482..29964
                     /locus_tag="VQ879_001025"
     CDS             29482..29964
                     /locus_tag="VQ879_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3143191.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29966..31507
                     /locus_tag="VQ879_001026"
     CDS             29966..31507
                     /locus_tag="VQ879_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3143192.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31563..32366)
                     /locus_tag="VQ879_001027"
     CDS             complement(31563..32366)
                     /locus_tag="VQ879_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3143193.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32449..32670)
                     /locus_tag="VQ879_001028"
     CDS             complement(32449..32670)
                     /locus_tag="VQ879_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143194.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33149..33358)
                     /locus_tag="VQ879_001029"
     CDS             complement(33149..33358)
                     /locus_tag="VQ879_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143195.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ879_001030"
     CDS             33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ879_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3143196.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33820..34059
                     /locus_tag="VQ879_001031"
     CDS             33820..34059
                     /locus_tag="VQ879_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3143197.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT        10381 a         6358 c         7395 g         9968 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcaaaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtc agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggtaatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaactgcgt caacgtcgcc ttggattata tatgtgactg acttcgtcag tcttatctac
    10741 aacctcaaag cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt
    10801 cattgagtat aagaacctat caaaaagtga gggaaacccc tcggaattat aaatagaaag
    10861 agtgaatctt atgctccaac aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct
    10921 gttagcccta ggatatacca tggtttacgg aattatcaag ctcatcaact tcgcccatgg
    10981 tgatatttat atgatgggag cctttatcgg ttatttcttg atcaattctt tccaaatgaa
    11041 tttctttgta gcgcttattg tagctatgct agcgacagct attcttggtg tcgtgattga
    11101 gtttcttgct taccgacctt tgcgccactc tactcgtatt gctgttttga ttacggctat
    11161 tggggtttct ttcctattgg agtatggaat ggtctatctg gttggtgcca atacccgtgc
    11221 cttccctcaa gcgattcaaa cagttcgata tgatttggga ccaattagct taacaaatgt
    11281 gcagttaatg attttgggca tttccttgat tttgatgatt ttgttacaag tcattgtcca
    11341 aaagactaag atggggaaag ccatgcgtgc agtatcagta gatagcgacg cggcgcaatt
    11401 gatggggatc aatgtaaacc gtacgattag ctttaccttc gctttgggtt ctgctcttgc
    11461 gggtgcggct ggtgttctga ttgctcttta ttataactct cttgagcctt tgatgggggt
    11521 tactccaggt cttaaatctt tcgttgccgc agtacttggt ggtatcggaa ttattcctgg
    11581 tgcggctctt ggtggctttg tgattggtct attggaaacc tttgcgactg cctttgggat
    11641 gtcagatttc cgtgatgcca ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc
    11701 agctggtatc cttggtaaga atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa
    11761 agttaatatt ctatggttac tccttttgtt agctggctat agcttgatta gtgtactggt
    11821 ttcagtcgga gtacttaatc tattctatgt acagatttta caacaaattg gaattaatat
    11881 tattttggct gttggtctca acttaatcgt tggtttttca ggacaatttt cacttggtca
    11941 tgctggtttc atggcgattg gtgcctatgc agcagctatt attggttcta aatcaccaac
    12001 ctacggtgcc ttctttggag ctatgcttgt aggggctttg ctttcaggag cagttgcctt
    12061 acttgtcggc attccaacct tgcgcttgaa gggggactat cttgcggtag caactctagg
    12121 tgtttctgaa attatccgta tctttatcat caatggtgga agccttacaa atggtgcggc
    12181 aggtatttta gggattccta actttacaac ttggcaaatg gtttacttct ttgtcgtgat
    12241 tacaaccatt gcaaccttga acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt
    12301 tcgtgaagat gaaatcgctg ctgagtcagt tggggttaat acgactaaaa ttaaaatcat
    12361 cgcttttgtc tttggtgcca ttactgcaag tattgctggg tcacttcagg caggatttat
    12421 cgggtctgtt gtaccgaaag attacacctt catcaactca atcaacgttt tgattattgt
    12481 tgtatttggt ggactcggtt ccattacagg tgcgattgtt tcggctattg ttctgggaat
    12541 tttaaatatg cttctccaag atgttgctag tgtgcgtatg attatttacg ctttggcctt
    12601 ggtattggta atgattttca gaccaggtgg actccttgga acgtgggaac tgagcctatc
    12661 acgtttcttt aaaaaatcta agaaggagga acaaaactaa tggcattact tgaagtaaaa
    12721 cagttaacca aacattttgg tggtctaaca gctgttggag atgtgactct tgaattgaac
    12781 gaaggggaac tggttggatt aatcggtcca aacggagctg ggaaaaccac ccttttcaac
    12841 cttttgaccg gtgtttatga accaagcgag ggaacagtaa ccctagatgg tcaccttttg
    12901 aatgggaaat caccttataa gattgcctct ttgggacttg gacgtacttt ccaaaatatc
    12961 cgtctcttta aagatttaac agttttagat aatgttttga ttgcttttgg aaaccatcac
    13021 aaacagcatg tttttactag tttcttacgc ttaccagctt tttacaagag tgaaaaagaa
    13081 ttaaaggcta aagctttgga attgttgaaa atctttgatt tagatggtga tgcagagact
    13141 cttgctaaaa atctttccta cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct
    13201 acggaaccta aaattctctt cttagatgaa ccagcagcag gtatgaaccc acaggaaaca
    13261 gccgaattga ctgagttaat tcgtcgtatc aaagatgaat ttaagattac aatcatgttg
    13321 attgaacacg atatgaatct ggtcatggaa gtaacagaac gtatctacgt acttgaatat
    13381 ggccgtttaa ttgctcaagg aactccagac gaaattaaga ccaataaacg cgttatcgaa
    13441 gcttatctag gaggtgaagc ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt
    13501 acggtatgat ccaagcagtc cgtgatgtaa gctttgaagt taatgaagga gaagttgttt
    13561 cccttatcgg tgccaacggt gcaggtaaga caactattct tcgcaccttg tcaggtttgg
    13621 ttcgaccaag ttcaggaaag attgaatttt taggtcaaga aatccaaaaa atgccagctc
    13681 agaaaatcgt ggcaggtggt ctttcacaag ttccagaagg acgccacgtc tttcctggct
    13741 tgactgttat ggaaaatctt gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc
    13801 aagcaaactt gaagaaggtt ttctcacgct ttcctcgtct tgaagaacgt aagaaccaag
    13861 atgcagctac tctttcagga ggggaacaac aaatgcttgc catgggacgc gctcttatgt
    13921 caacaccaaa acttcttctt ttagatgaac catcaatggg acttgcccca atcttcatcc
    13981 aagagatttt tgatatcatt caagatattc agaagcaaga aacaaccgtc ctcttgattg
    14041 aacaaaatgc caataaagca ctcgcaatct ctgaccgagg atatgtattg gaaacaggaa
    14101 aaatcgtcct atcagggaca ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat
    14161 atctaggtgg ctaaaacaat ccagtggatt gttttagtcg gcagatgaag attacgaagt
    14221 aatcatcaat atagtccggg ggaccttttt agtcggtaga ttgagattgc aaacaaatat
    14281 gcatctacat tgaaagctta atttctaata attgaaaaaa tcgaatgaaa aatttcttac
    14341 cttcattcac agagctctat ttcagagctc tttttgctag cttattcata cttttctgaa
    14401 tttcgaaaaa gaaatgtaag cgtttgatag atttacaaaa agattgtata atagggataa
    14461 gaatagaaaa ggagaagtct catggcagtt aaagatttta tgacccgcaa ggtagtttat
    14521 attagtccag atacaacagt atctcatgca gcagatttga tgagagagca aggtttgcac
    14581 cgtctgcctg ttatcgaaaa tgatcaatta gttggtttgg tgactgaggg aaccattgca
    14641 caagcaagtc catctaaagc aacaagtctt tctatctatg agatgaatta tcttctgaat
    14701 aagacaaaag taaaagatgt catgattcgc gatgttgtca ctgtctcagg ctatgctagt
    14761 ctagaagatg caacttatct gatgttgaaa aataagatta gtattctccc tgtcgtagat
    14821 aaccatcaag tatacggagt tattactgac cgtgacgttt tccaagcctt tcttgaaatt
    14881 gcaggttatg gcgaagaagg gattcgtgta cgctttgtta cagaagatga agttggtgtt
    14941 cttggaaaaa ttgtttcttt gattgtagaa gaaaatttga atatctccca tacagtcaat
    15001 attccgcgta aggatggtaa ggtgattatc gaagtgcaaa tcgatggatc aattgattta
    15061 ccagccttga aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat cgctcgcact
    15121 tcagcaaaag tcttgtaaga agggaagccc aaaggcttct tttttcatga aaaggggatt
    15181 agagcaaaag atggaaagaa atgataaaat atgctataat gaaataatgt aaaaaaggag
    15241 tatttatgga catttcagta attcgtcaga aaattgacgc aaatcgtgaa aaattagctt
    15301 ctttcagggg gtctctttga cctcgaaggg ctagaggaag agattgccat cttggaaaac
    15361 aagatgacag aacctgattt ttggaacgat aatattgcgg cccaaaaaac gtcgcaagaa
    15421 ttgaatgaat taaaaaacac ttacaatacc ttccataaga tggaagagtt gcaggatgaa
    15481 gtcgaaattt tattggattt tttggctgaa gacgagtcag tgcatgatga actggtagcg
    15541 cagttagccg aacttgataa gataatgacc agctacgaga tgactctact attgtcagaa
    15601 ccttatgacc acaacaatgc catcttggaa atccatccag gttctggtgg tactgaggcg
    15661 caggactggg gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc taaaggcttt
    15721 aaagtggaag tgttggatta ccaagcaggt gatgaggctg gtattaagtc ggtaacttta
    15781 tcatttgaag ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt tcatcgctta
    15841 gtgcgaatct caccatttga ctctgccaaa cgtcgccata cctctttcac atctgtagaa
    15901 gtgatgccag aattggatga tactattgaa gtggaaatcc gtgaagatga tatcaagatg
    15961 gataccttcc gttcaggtgg tgccggtgga caaaacgtca ataaggtttc aacaggtgta
    16021 cgtttaaccc acattccaac tggaattgtt gtccaatcaa cagtggatcg tacccagtat
    16081 ggaaatagag atcgtgccat gaagatgttg caggctaagc tctatcaaat ggagcaagat
    16141 aagaaggctg cggaggtaga ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc
    16201 caaatccgtt cttatgtctt cacgccttat actatggtaa aagatcaccg aactagcttt
    16261 gaggttgctc aggtagataa ggttatggat ggggacctag atggttttat cgatgcttat
    16321 ctcaagtggc gaattagcta agatagaaag gaactcacat gtcaattatt gaaatgagag
    16381 atgtcgttaa aaaatacgac aacggaacga ctgctctacg cggtgtttcg gttagcgttc
    16441 aaccggggga atttgcttac atcgtaggac cttcaggagc agggaagtca acttttattc
    16501 gttctctgta tcgtgaagta aaaatcgata aaggaagtct atcagttgct ggttttaatc
    16561 tggttaagat caaaaagaaa gatgtcccgc ttctacgtcg tagtgttggg gttgtcttcc
    16621 aagattataa attgttacca aagaaaactg tctatgaaaa tattgcttac gctatggaag
    16681 taatcgggga aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg gacttggttg
    16741 gattgaagca taaggttcgt tctttcccaa atgaactctc aggtggggag cagcagcgaa
    16801 ttgcgattgc gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat gagccaacag
    16861 gaaatctgga tccggataat tcatgggaaa ttatgaatct cttggaacgg attaacctac
    16921 aagggacaac tattttgatg gcgactcata atagccagat tgtaaatacc ttgcgccacc
    16981 gtgtcattgc cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat
    17041 acgatgatta gtagattttt tcgccattta tttgaagcct taaaaagttt gaaacgaaat
    17101 ggttggatga cagtagctgc tgtcagttca gtcatgatta ctttgacctt ggtggcaata
    17161 tttgcatctg ttattttcaa tacagcgaaa ttagctacag atattgaaaa taatgtccgt
    17221 gtagtagttt atatccgaaa ggatgtggaa gataatagtc agacaattga aaaagaaggt
    17281 caaactgtta caaataatga ctaccacaag gtatatgatt ctttgaagaa catgtctacg
    17341 gttaaaagtg ttaccttttc aagtaaagaa gaacaatatg aaaaattaac cgagataatg
    17401 ggagataact ggaaaatctt tgaaggagat gccaatcctc tctatgatgc ctatattgta
    17461 gaggcaaaca ctccaaatga tgtaaaaact atagccgaag atgctaaaaa aattgaaggt
    17521 gtctctgagg ttcaagatgg cggtgccaat acagaaagac tcttcaagtt agcttcattt
    17581 atccgtgttt ggggactagg gattgctgct ttgttaattt ttatcgcagt tttcttgatt
    17641 tcaaatacca ttcgtattac cattatttcc cgcagtcgcg aaattcaaat catgcgcttg
    17701 gttggagcta aaaacagtta tatccgtgga ccgttcttgt tagaaggagc ctttatcggt
    17761 ttattgggag ctatcgcacc atctgttttg gtctttattg tttatcaaat tgtttaccaa
    17821 tctgtcaaca aatcgttggt agggcaaaat ctatccatga ttagtccaga tttatttagt
    17881 ccgttgatga ttgccctact atttgtgatt ggggttttca ttggttcatt gggatcagga
    17941 atatccatgc gccgattctt gaagatttag gtaaaatagc tgcttttatg aggagattgt
    18001 aaaatctcct tttttgctac aagagttttt gaaaagagat gcgtagaaga aaagagcttc
    18061 caaagaagtc ccccagagaa gacttcttga tggctaattt gaacttgaaa tttggcgcac
    18121 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
    18181 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
    18241 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
    18301 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
    18361 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
    18421 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
    18481 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
    18541 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
    18601 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
    18661 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
    18721 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
    18781 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
    18841 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
    18901 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
    18961 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
    19021 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
    19081 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
    19141 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
    19201 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
    19261 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
    19321 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
    19381 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
    19441 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
    19501 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
    19561 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
    19621 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
    19681 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
    19741 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
    19801 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
    19861 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
    19921 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
    19981 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
    20041 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
    20101 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
    20161 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
    20221 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
    20281 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
    20341 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
    20401 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
    20461 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
    20521 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
    20581 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
    20641 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
    20701 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
    20761 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
    20821 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
    20881 gccctagctg aaactgtagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
    20941 tggtgggata aaggttttca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
    21001 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
    21061 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
    21121 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
    21181 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
    21241 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatatt aaactggaaa
    21301 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
    21361 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
    21421 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
    21481 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagaca agttgattcc
    21541 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
    21601 tactttcttg ttaccgattt ttcagcaatt agatgaagct agcgatagtg tacaagcagt
    21661 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
    21721 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
    21781 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
    21841 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
    21901 tgaagcagat atgaccttgg atatgggatt cttggaaact gttgataaga ttgctgacag
    21961 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
    22021 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacca aaacggttat
    22081 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
    22141 ttaccagttg actcagtcga tgcagccgta tttggcaatg atttttgtta acactaaaac
    22201 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
    22261 tggcgatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
    22321 tgagtatatt gtcgcaacag atttggcagc acgtgggatt gacattgaag gtgtcagcca
    22381 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
    22441 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
    22501 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagacgggga
    22561 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
    22621 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
    22681 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg
    22741 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
    22801 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
    22861 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
    22921 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
    22981 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
    23041 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
    23101 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
    23161 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
    23221 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
    23281 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
    23341 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
    23401 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
    23461 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
    23521 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
    23581 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
    23641 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
    23701 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
    23761 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
    23821 tcaaagaagt tattccatct tcttatcttg atgataaggc aaaattcttt atcaatccga
    23881 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
    23941 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
    24001 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
    24061 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
    24121 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
    24181 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
    24241 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
    24301 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
    24361 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
    24421 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
    24481 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
    24541 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
    24601 taatcatggg gatatttcaa gccaaagttt tattcgttat cacttgacta ttgcaaggtt
    24661 ttctagatca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
    24721 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
    24781 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
    24841 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
    24901 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
    24961 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
    25021 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
    25081 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
    25141 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
    25201 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
    25261 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
    25321 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
    25381 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gatcaagcgg
    25441 cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct atcggaaacg
    25501 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
    25561 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
    25621 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
    25681 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
    25741 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
    25801 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatca aaaaatctga
    25861 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
    25921 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaaa
    25981 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
    26041 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
    26101 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
    26161 atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca accaagttga
    26221 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
    26281 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
    26341 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
    26401 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
    26461 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
    26521 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
    26581 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
    26641 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
    26701 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
    26761 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
    26821 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
    26881 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
    26941 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
    27001 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
    27061 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
    27121 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
    27181 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
    27241 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
    27301 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
    27361 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
    27421 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
    27481 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
    27541 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
    27601 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
    27661 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
    27721 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
    27781 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
    27841 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
    27901 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
    27961 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
    28021 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
    28081 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    28141 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    28201 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    28261 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    28321 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    28381 agaataagga gaagaaatga aaccctcaat tcatagtttg acacatcaaa ccatgcagga
    28441 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    28501 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    28561 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    28621 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    28681 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    28741 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    28801 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    28861 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    28921 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    28981 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    29041 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    29101 tgcctttccg attgaaaaac tctttgctgc tattgaatac tacattgaga caacaaaccg
    29161 tcgtgtaacc tttgaatata tcatgcttaa tgaagtcaac gacggtgtgg aacaagcctt
    29221 ggaattggct gaattgctca agaacatcaa gaaatcgtct tatgtaaact tgattcctta
    29281 taacccagtt agtgagcatg accaatatag ccgtagtccc aaagagcgcg tgttggcttt
    29341 ctatgatacg cttaagaaaa aagggggcaa ctgtgtggtt cgtcaagagc atggtacaga
    29401 tattgacgca gcttgtggac aattgctctt taacacaatg aaacgtgacc gccagaaggc
    29461 agtcgcagcg gtaaatcctt aatgatgaag aagacttata atcatatttt ggtctgggga
    29521 gtcattttct atagcatttg cattgtctat ttttgcttta ctcctcaaga acaatctacc
    29581 gtgggagtgg gaactccaga tattcagcat cttggacgcc tggtttttct tttgactcct
    29641 ttcaattctc tctggaaact gggcgaagtg agtgacattg gacaattatg ttggattttt
    29701 ttacaaaata tcctcaatgt cttcttgttt tttcctctga ttttccaact cctttatcta
    29761 tttccaaatt tgcggaaaac aaaaaaggtc cttcttttta gttttcttgt gagtcttgga
    29821 atcgagtgta cgcaattaat cttggacttt ttctttgatt tcaatcgcgt ctttgagatt
    29881 gatgatttgt ggaccaacac tttgggtggc tatctggctt ggctccttta taaacgatta
    29941 cataaaaaca agataaggaa ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg
    30001 ttttggtgac cgtgcaattt ttgaagatgt gtccttccgt ctcctcaagg gggaacatat
    30061 cggcctggtc ggtgccaatg gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa
    30121 aatgctgcca gatgaaggaa aggttgagtg gtccaaatat gtgacggctg gttacttgga
    30181 tcagcactct gtccttgctg aaagacagtc ggtgcgtgat gttctccgta cggcttttga
    30241 tgagcttttc aaagctgaag ctcgtatcaa tgacctctat atggaaatgg ctgaagacgg
    30301 tgcggatgtt gatgctctca tggaagaagt aggagaactt caagaccgtc tggagagtcg
    30361 tgatttctat accttggatg ctaagattga cgaagtagcg cgtgctcttg gtgttatgga
    30421 ctttggcatg gatacggatg taacttcttt gtcaggtggg caaagaacca aggtgctttt
    30481 ggcaaaactt ctccttgaaa agcctgatat cttgctgttg gacgagccga ccaactactt
    30541 ggatgctgag catattgatt ggctcaagcg ctatctccaa aactatgaga atgcctttgt
    30601 tctcatttcg cacgatattc cattcctcaa tgacgttatc aatattgtct atcatgtgga
    30661 aaatcaacag ctgacgcgtt actctggtga ctactaccag ttccaagaag tttatgctat
    30721 gaagaaatct cagctagagg cagcctacga acgccagcag aaagagattg cagacctcaa
    30781 ggactttgtg gctcgtaata aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca
    30841 aaagaaattg gataagatgg atattatcga actccaaagt gagaaaccaa aaccatcctt
    30901 tgatttcaaa ccagctcgta caccagggcg ctttatcttc caaaccaaga acttgcaaat
    30961 tggttacgac cttcctctta ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt
    31021 tgcgattatt ggtgctaatg gtattggaaa aacaactctc ttgaagagtc tcttgggcat
    31081 tatctcgcca atcgctgggg aagtggagcg tggagattat ttagaacttg gttattttga
    31141 gcaggaagta gaaggcggta atcgccaaac tcctcttgaa gctgtctgga atgcctttcc
    31201 tgcccttaat caagcagaag tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca
    31261 tattgaaagc cagattcaag tattatcagg gggagagcaa gccaaggttc gtttctgtct
    31321 cttgatgaat cgtgaaaaca acgttttagt gctggacgag ccgaccaacc atttggatgt
    31381 ggatgcaaag gatgagctca aacgcgctct caaagaatat aggggatcta tccttatggt
    31441 ctgccacgag ccagactttt atgaaggctg gatagaccaa atatgggatt ttaataattt
    31501 aacttaagaa tgagagtaaa agaaatacag taccgaatgt ggatactgta tttttttggt
    31561 ttttaagatt taaaatcgta gtctttcacc acttcgatgc tgtcgattgt gatagcagta
    31621 gttggcttgt ctttttcatc tttttcggcc ttagcaatct tatccacaac atccataccg
    31681 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
    31741 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
    31801 gagctttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
    31861 gcaagagcac cacggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
    31921 ttgtctttag tcttatcctt gtcatgccag atggactgac cacctgtacc gtcccctttt
    31981 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
    32041 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
    32101 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
    32161 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
    32221 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
    32281 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
    32341 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataccattgt
    32401 accctaaaaa gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32461 tgggatttca tcatcatctt gaaaatcttc aacttcttca acttcttccc cagtaaatgg
    32521 tttctgaaaa gaacttagta taaaacgggc aattggttca acaattagga aatttagagg
    32581 aagagctgca ataaagttta cgaaccaggc gcttagatag gtattgggtg tgatagcaat
    32641 gccattgtaa aaaagtccat agaaggacat gaaagtgacc agctaattct tcttctgaaa
    32701 aatgctcatg aagggcttga tccaggtcgc aagatttcat tttagaaagt ccagtaactc
    32761 ccttcttctt caggatattc tttttcatgg tattatttag atggtcaagt gagtcaaaag
    32821 aagtttcgac aagagcatac cctttttcta tcagagtttt tagatgttta ggggcatcaa
    32881 taccataagt gtactcaaag tattttggaa accagatctt aagaaagctc gtaaagctag
    32941 ccagttctct aaacgctaag aactagctac aacacagcat ttacaacact tcatggttca
    33001 caccatgggg tgctttttaa tgattttaag caaaattcac acttaattga aagttattta
    33061 aattagatga aaatttattt tttgaaaaag cgggaaaaca ttgattctaa gcgaattttg
    33121 aatcatattc gaatgggagt ttttaaaatc atgtttcagt ggtaaaagta ccaaactgga
    33181 ttctccatag taaaatgata tctcctgcta gtgaatcatc tactaataag tccatatttc
    33241 gcttgggaac gggcttggga cttagaagcc aagtatccaa ctctcgttca ggcgatatga
    33301 agggtttgac ttggtgttct ttataaaatt tttctaaaat agtattcacg gatagcatct
    33361 ttcaaacatt tatttcctat tctaacaaat ttctaaatac tttaagaaat ttatagtctg
    33421 tcaagttttt ttcttgacac atgccagaaa tctgctataa tagaacatgt gctaaatagc
    33481 tcagctattt caccgaaata aaaaattaaa gaaatgagac tttaaaaatg gcagttaaaa
    33541 tccgtttgac tcgtatgggt tctaagaaaa aacctttcta ccgtatcaac gtagcagatt
    33601 cacgttcacc acgtgacgga cgtttcatcg aaacagttgg aacttacaac ccacttgttg
    33661 ctgaaaacca agtaactttg aaagaagacc gcgttcttgc atggttggct aatggagctc
    33721 aaccttcaga cacagtacgt aacatccttt caaaagaagg cgtattgaaa aaattccacg
    33781 attctaaatt ctcaaaataa gtttaaagta ggttgacaga tggatacgat tgaaaatctc
    33841 attattgcga ttgtgaaacc cttaatttca caaccagatg ccttaactat caagattgag
    33901 gatacaccag aatttttgga atatcatttg aatcttgatc aaagcgatgt gggtcgtgta
    33961 atcggtcgta agggtcgcac tatttctgcg ataagaacga ttgtctactc tgtcccaact
    34021 gaatacaaaa aagtaagaat cgttattgac gaaaaataag aagggcggga cggatgtctc
    34081 gcttttttgt gtggaataga ag
//
LOCUS       DAVBOU010000020        33674 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBOU010000020 DAVBOU010000000
VERSION     DAVBOU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33674
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.020"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            426..686
                     /locus_tag="VQ879_001032"
     CDS             426..686
                     /locus_tag="VQ879_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143198.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            640..860
                     /locus_tag="VQ879_001033"
                     /pseudo
     CDS             640..860
                     /locus_tag="VQ879_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1179..2108
                     /locus_tag="VQ879_001034"
     CDS             1179..2108
                     /locus_tag="VQ879_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3143199.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            2122..3045
                     /locus_tag="VQ879_001035"
     CDS             2122..3045
                     /locus_tag="VQ879_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3143200.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            3129..4604
                     /locus_tag="VQ879_001036"
     CDS             3129..4604
                     /locus_tag="VQ879_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3143201.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            4876..5862
                     /locus_tag="VQ879_001037"
     CDS             4876..5862
                     /locus_tag="VQ879_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3143202.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            5984..6844
                     /locus_tag="VQ879_001038"
     CDS             5984..6844
                     /locus_tag="VQ879_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3143203.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(7021..8085)
                     /locus_tag="VQ879_001039"
     CDS             complement(7021..8085)
                     /locus_tag="VQ879_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143204.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(8148..9059)
                     /locus_tag="VQ879_001040"
     CDS             complement(8148..9059)
                     /locus_tag="VQ879_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3143205.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(9052..9645)
                     /locus_tag="VQ879_001041"
     CDS             complement(9052..9645)
                     /locus_tag="VQ879_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3143206.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(9632..9958)
                     /locus_tag="VQ879_001042"
     CDS             complement(9632..9958)
                     /locus_tag="VQ879_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3143207.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(10097..11260)
                     /locus_tag="VQ879_001043"
     CDS             complement(10097..11260)
                     /locus_tag="VQ879_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3143208.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYT
                     AMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSL
                     AGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLS
                     QTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            11318..12457
                     /locus_tag="VQ879_001044"
     CDS             11318..12457
                     /locus_tag="VQ879_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3143209.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            12525..14375
                     /locus_tag="VQ879_001045"
     CDS             12525..14375
                     /locus_tag="VQ879_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3143210.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(14554..14652)
                     /locus_tag="VQ879_001046"
                     /pseudo
     CDS             complement(14554..14652)
                     /locus_tag="VQ879_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14678..15310)
                     /locus_tag="VQ879_001047"
     CDS             complement(14678..15310)
                     /locus_tag="VQ879_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3143211.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(15332..16204)
                     /gene="sdaAA"
                     /locus_tag="VQ879_001048"
     CDS             complement(15332..16204)
                     /gene="sdaAA"
                     /locus_tag="VQ879_001048"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3143212.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(16213..16884)
                     /gene="sdaAB"
                     /locus_tag="VQ879_001049"
     CDS             complement(16213..16884)
                     /gene="sdaAB"
                     /locus_tag="VQ879_001049"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3143213.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            17126..17698
                     /locus_tag="VQ879_001050"
     CDS             17126..17698
                     /locus_tag="VQ879_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3143214.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(17750..18070)
                     /locus_tag="VQ879_001051"
     CDS             complement(17750..18070)
                     /locus_tag="VQ879_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3143215.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            18495..18779
                     /locus_tag="VQ879_001052"
     CDS             18495..18779
                     /locus_tag="VQ879_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3143216.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            18834..20942
                     /locus_tag="VQ879_001053"
     CDS             18834..20942
                     /locus_tag="VQ879_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3143217.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            20939..21580
                     /locus_tag="VQ879_001054"
     CDS             20939..21580
                     /locus_tag="VQ879_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143218.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            21787..22593
                     /locus_tag="VQ879_001055"
     CDS             21787..22593
                     /locus_tag="VQ879_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3143219.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            22559..23029
                     /locus_tag="VQ879_001056"
     CDS             22559..23029
                     /locus_tag="VQ879_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3143220.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(23319..23639)
                     /locus_tag="VQ879_001057"
     CDS             complement(23319..23639)
                     /locus_tag="VQ879_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3143221.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            24403..24783
                     /locus_tag="VQ879_001058"
     CDS             24403..24783
                     /locus_tag="VQ879_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3143222.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            25157..26215
                     /locus_tag="VQ879_001059"
     CDS             25157..26215
                     /locus_tag="VQ879_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143223.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            26530..27506
                     /locus_tag="VQ879_001060"
                     /pseudo
     CDS             26530..27506
                     /locus_tag="VQ879_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            27883..28257
                     /locus_tag="VQ879_001061"
     CDS             27883..28257
                     /locus_tag="VQ879_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3143224.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            28465..29367
                     /locus_tag="VQ879_001062"
     CDS             28465..29367
                     /locus_tag="VQ879_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143225.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            29423..29776
                     /locus_tag="VQ879_001063"
     CDS             29423..29776
                     /locus_tag="VQ879_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3143226.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            29773..30501
                     /locus_tag="VQ879_001064"
     CDS             29773..30501
                     /locus_tag="VQ879_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143227.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            31633..31872
                     /locus_tag="VQ879_001065"
     CDS             31633..31872
                     /locus_tag="VQ879_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143228.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            32422..>33674
                     /locus_tag="VQ879_001066"
     CDS             32422..>33674
                     /locus_tag="VQ879_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3143229.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATGWL"
BASE COUNT        10569 a         5597 c         6981 g        10527 t
ORIGIN      
        1 agtgtattga atttataaca gtacaccttg gctgctaaaa tatttctata aattaatttg
       61 actttcctga tagagttgtt cacatcttat ttcaaatcac tataaaagct ctataatctc
      121 tttattaaga tttgcccatc agacgaaata taatggattg aaactagaat agtacacatc
      181 tacttctaaa acattgttag aaatcgattt gactgtcctg atcgatttgt cctgttcttg
      241 tttcatttta ctatagaacg atttgaaggc gtttatgata tttagctgta cgagagtctt
      301 ttaaaagtgt tttgatagtt tggatttctt ctttagttga tttcatatca ctgttatata
      361 atgctttttg attttagtct agtattagta agcagactca aaccttagaa aatcttttga
      421 gatcattgac aggtgtatcg aatcctacca cagattcagc acgtctggtt ttggcagagg
      481 ctaagaaagc ttttgcagat gatagtttga cagagcaagg tttacgtgat attttgcaaa
      541 cagtcaaaga tgccattgct tccctagagt ccattaagga aagccagtca gcaactaagg
      601 atggaggaca aacagcgggc aaagaaacag caggagaaga tgagtctgca aatcaaactc
      661 aagaaattag ccaaggaatt aagtaaactt cttaaagact caaaccttga aacagtagat
      721 aaggatgtcc ttgaaaactc tcaaaaagaa cttcaaaaag cagttttgtt cttggcagat
      781 gaaaaagctc tgagcatact gaagcagagg tgattgataa tcttaaagag gttattgcta
      841 agttgaaagc aaacgcctaa taacatatta aaaatctcca gattaggaac tatctctgag
      901 ttccctagtc tggagatttt tcagtatacc ccgttgttgg atgcttataa cagagtgacg
      961 ccatcactgg gctaatagag ataaaataaa caattgattt aggacatttg tttgatagtg
     1021 gtgataaagt tttaaatctg ctacataatt tgtggagttt tttctataat taggagttta
     1081 acctaacctg caaataggag tatactaata atgtaatcgt tatcaaaagt ctaaaaaaga
     1141 atttttagat ggatatcaaa ataaaaaggg aggaaattat gaaaaagttt tcaaaaacat
     1201 tgagagacaa ctggatcttt ctcttgatgg ttttgccagg gacactctgg ttgattctat
     1261 tcttttacat tccagtattt gggaacgtgg ttgccttcaa agactaccac atgaccagta
     1321 atggtttcat agatagtatc ataaatagta aatgggtcgg actcgataat ttcagattct
     1381 tatttagttc aagagacgcc tttattatca cacgaaatac tgtcctctac aatcttggct
     1441 ttatctttct aggtttagtt gtatctgtag ggattgccat tatcctcagc gagctccgtt
     1501 ctaagagaat ggtgaagatt ttccaaactt ctatgttgtt cccttacttc ttgtcttggg
     1561 ttatcatcag tttctttaca gatgccttcc taaatattga taaaggggtg ttcaatcatc
     1621 tattggaaag tcttggtctc aaagaagtca atttttacgc tgacctgggc atctggccct
     1681 atctcctact tttcctaggt atttggaaag gctttggata tagcagtgtc atgtactatg
     1741 cgacgatcat gggaattgat ccaacctact acgaagcagc gacagtggac ggagctagca
     1801 agtggcaacg tattcgcaac gtaaccattc ctcagttgac tccgcttgta actgtattga
     1861 ccatccttgc agtcggaaat atcttccgcg cagactttgg tctcttctat caaatcccac
     1921 acaatgctgg tcagctttac aatgtaacca acgttttgga cgtatatgtc tttaatggtt
     1981 tgactcagac agcagatatc ggtatggctg cagcagccgg tctttaccaa tccgttgttg
     2041 gtttgattct ggttatccta tcaaacttgc ttgcaagacg agtcgatcca aactcagctt
     2101 tgttctagaa aggaggagaa tatggcaaaa aagaaaatta aaaaagaaaa aattgataat
     2161 gtcggcattc actccttcag taagaaagca gatatcttct tcagtatcat ttcgggtttg
     2221 attgccctct cttgtatcct accttttgta ttcgttatca ttatttcagt gacagacgag
     2281 aaaagcctcc tccaatacgg ctatagcttc ttcccatccc aatttggctt agacggtttt
     2341 gagtttttgg cacagtttaa ggataaaatc ctacaagccc tcttcatctc tgtctttgta
     2401 accgtagttg ggacattgac aaatgtcttt atcacaacaa cctatgccta cgctatttca
     2461 cggacaacct ttaagtatcg cagatttttt accatcttcg tccttctcag tatgttgttc
     2521 aacgctggtt tggtaccagg ttatatcatg gtgacccgtg tacttcagct tggtgacact
     2581 gtttgggcct tgattgttcc aatgcttctc tcaccattca atatcatctt gatgcgttcc
     2641 ttcttcaaga agaccattcc agaagccatt ctcgaatcgg ctcgtatcga tggtgccagt
     2701 gaggcccgga ttttcttcca aatctgtttg ccattgtcac taccaggtat cgcaaccatc
     2761 acgcttttga cagctcttgg tttctggaat gactggttca acgcccttct ttacatcaag
     2821 agtgataact tgtatccatt gcaatatttg ctcatgcaaa tccaacaaaa tatggactac
     2881 attgccaaag cggtcggctt gactggtcaa ctgggagttg ctctaccgaa agaaacaggt
     2941 cgtatggcca tggttgtggt agcaaccctt ccaatcgcga ttttgtatcc attcttccaa
     3001 cgctactttg taaaaggttt gactatcggt ggtgtgaaag aatagcactt gtttccaaac
     3061 ttcccttgcg tgaagttaag atcattacat tgtttataag tttaaaaata aaaaaaggag
     3121 tttttatcat gaaaaactgg aaaaaatatg cttttgcatc tgctagtgta gttgctttgg
     3181 ctgcaggtct tgctgcttgt ggcaacttga caggtaacag caaaaaagct gctgattcag
     3241 gtgacaaacc tgttatcaaa atgtaccaaa tcggtgacaa accagataac ttggatgaat
     3301 tgttagcaaa tgccaacaaa atcatcgaag aaaaagttgg tgctaaattg gatatccaat
     3361 accttggctg gggtgactat ggtaagaaaa tgtcagttat cacatcatct ggtgaaaact
     3421 atgatatcgc ctttgcagat aactatattg taaatgctca aaaaggtgct tatgctgact
     3481 tgacagaatt gtacaaaaaa gaaggtaaag acctttacaa ggcacttgat ccagcttata
     3541 tcaagggtaa tactgtaaat ggtaagattt acgctgtacc agttgcagcc aacgtagcat
     3601 catctcaaaa ctttgccttc aacggaactc tccttgccaa atatggtatc gatatttcag
     3661 gtgttacttc ttacgaaact cttgagccag tcttgaaaca aatcaaagaa aaagctccag
     3721 acgtagtacc atttgctatt ggtaaagttt tcatcccatc tgataacttt gactacccag
     3781 tagcaaacgg tcttccattc gttattgacc ttgaaggcga tactactaaa gttgtaaacc
     3841 gttacgaagt acctcgtttc aaagaacact tgaagactct tcacaaattc tatgaagctg
     3901 gctacattcc aaaagacgtc gcaacaagcg atacttcctt tgaccttcaa caagatactt
     3961 ggttcgttcg tgaagaaaca gtaggaccag ctgactacgg taacagcttg ctttcacgtg
     4021 ttgccaacaa agatatccaa atcaaaccaa ttactaactt catcaagaaa aaccaaacaa
     4081 cacaagttgc taactttgtc atctcaaaca actctaagaa caaagaaaaa tcaatggaaa
     4141 tcttgaacct cttgaatacg aatccagaac tcttgaacgg tcttgtttac ggtccagaag
     4201 gcaagaactg ggaaaaaatt gaaggtaaag aaaaccgtgt tcgcgttctt gatggctaca
     4261 aaggaaacac tcacatgggt ggatggaaca ctggtaacaa ctggatcctt tacatcaacg
     4321 aaaacgttac agaccaacaa atcgaaaatt ctaagaaaga attggcagaa gctaaagaat
     4381 ctccagcgct tggatttatc ttcaatactg acaatgtgaa atctgaaatc tcagctattg
     4441 ctaacacaat gcaacaattt gatacagcta tcaacactgg tactgtagac ccagataaag
     4501 cgattccaga attgatggaa aaattgaaat ctgaaggtgc ctacgaaaaa gtattgaacg
     4561 aaatgcaaaa acaatacgat gaattcttga aaaacaaaaa ataatcagct aaattgattt
     4621 cgtgtattca ttcctaactc ctaaaataag aatcactgct ttcctcaggt tggtctgggg
     4681 gagacagtgg tttttttggc acaaggatat agatatccat gttttctctt gtccttattt
     4741 taaccattca ggaaatttcg agaaccctct acaatttcca gtcaaataaa ttgcattcgt
     4801 tttctcaagc aggtatacta gtgtagataa ataaaaaatt tagaaaattt aagaatagaa
     4861 aagagaacaa atcttatggc aaaagatatt cgtgtcttac tttactacct ttatactcca
     4921 attgaaaatg cagagcaatt tgctgcagac cacttggctt tctgtaaatc aatcggtctt
     4981 aaaggccgta tcctagtcgc tgacgaggga attaacggaa cagtttcagg tgactatgaa
     5041 acaactcaaa aatacatgga ctacgttcac agccttccag gaatggaaga actctggttc
     5101 aagattgacg aagaaagtga acaagccttc aagaagatgt ttgttcgcta caagaaagaa
     5161 attgtccacc ttggtttgga agacaacgac tttgacaatg acatcaaccc acttgaaaca
     5221 acaggtgctt acttgtctcc aaaagagttc aaagaagcgc ttcttgataa agataccgtt
     5281 gtccttgaca cacgtaatga ttatgagtat gacctaggac atttccgtgg ggctattcgc
     5341 ccagatattc gcaacttccg tgagttacca caatgggtcc gtgataacaa ggaaaaattc
     5401 atggacaagc gtgtcgtggt ttactgtaca ggtggcgttc gctgtgagaa attctcaggc
     5461 tggatggttc gtgaaggtta caaagatgtc ggccaattgc acggaggaat cgcaacttac
     5521 ggtaaagacc cagaagttca aggtgagctt tgggatggga aaatgtacgt ctttgacgag
     5581 cgtattgccg ttgatgtcaa ccatgtcaac ccaactatcg tagggaaaga ctggtttgat
     5641 ggaacaccat gtgaacgtta tgtcaactgt ggaaatccat tctgtaaccg tcgtatcttg
     5701 acatcagaag aaaatgaaga caagtacctt cgtggatgct cacacgagtg ccgtgttcac
     5761 ccacgtaacc gctatgtttc aaaaaatgaa ttgacacaag ctgaagtgat tgagcgccta
     5821 gccgctatcg gtgaaagctt ggatcaagca gctactgtat aagatcaaac agtcctcagg
     5881 ggctgttttt ctatgctttg tactcaaaaa tctaaagttt gtttctgtat ctttcagaaa
     5941 aataaggtat actgtatgta aacgatttca aaggagtcca gttatggcaa aaacattttt
     6001 tattccaaat aaacagagca ttttaggaga acaagagatt ttgaatgcca agtcgatctt
     6061 ggccttgcta gacggtttgg agtcacatag ctatgatgta gtctatctcc gtcagcctct
     6121 taatcgtctc gagtatattg agtgtgcgat agtggggcaa tcacaatttc tttttaaggt
     6181 cagttatgct gatggtcaaa aggcttaccg tgtcgatctt cctgacctac taacaaagac
     6241 agactggcag attatcaagt catttttaga tgctttgctt gcttatacag ggactgatat
     6301 tgaagggcta gatggttttg attttgaagc ttatttccaa gcaagtattc aagcctatct
     6361 agcagaccct gtagctcgtt ttacgatttg ccaaggaatt tttaatccta ttttctttag
     6421 tcgtgagaac ttgaaaagct ttttagaggc agatggcttg gctcagtttg aagcgcgtgt
     6481 gcgtgcggtt caagagacag atgcctactt tgcgagagtt tccttctatc aggatggaga
     6541 aggaaaagtg catggcgttt accatctagc tcaaggagtc aagacagttt taccgagaga
     6601 accgtttgtt cctgcagcct atattgagca attggtggat aaggaagtgc agtgggagat
     6661 tgacttggtt caaatcacag gagatggctc taaaccagaa gactatgaag ccattgcccg
     6721 cttggactat gcaaaattct tagaggtatt acccctatct ttttaccacc aactagacgc
     6781 caatcaaata gaagtgcaac ccatattaga caaagatttt aaagcattag cacaagaaga
     6841 gtaaagcaga agcaggtcaa tcgacttgct tttttgaaat agaaaaatcc tgccatgaaa
     6901 gacaggattg ctactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggctgta
     6961 cttgagtacg gtaaggcgaa gctgacgtgg tttgaatttg attttcgaag agtatgaagt
     7021 ttaaagaaag gccaagatac gaagataatc tccaatcagt gccacttcag ctacaaagaa
     7081 gaggaggata ataactccgt tcacaaggac agacaagaat aattgataga aggagtcggt
     7141 ttcacttgct tgacttggtc ttgtaatgat atggagactg gcaagcagaa tgattccaat
     7201 gctaatcaca cacaagaggg ctgtaaatcg taggctatca aagaaagcaa agaaactagc
     7261 aatagcagtg aggaagattg gaattgctaa gagttgacta tattgttgga gaaccttgtc
     7321 tagcgtccag tccttttcct ggtggataaa tcgtctcaca acgaaactac ccaagaggaa
     7381 tgaaaagaag aagagtgttg tcgctactag gatagagatg atagaaaaaa gagttaaagg
     7441 agctagctgc tcagggaagc gactgttaat gcttgctata tgtccatagt aagcatgttt
     7501 gatgtgatag atactaaaga aaaaggaaga tgcagaaaac agaatgagca agagaaaggc
     7561 tgtgtaactg tgtgtgatac ttgtttccaa cttacttgta ggagatttga tcgcttccac
     7621 tagccaagac caaaaatcaa gcacttgctc tttccattta tccctagatt ttggagcttg
     7681 gtcggggata taaggacttt ctaaagattt actgataaga agtggctctt tcgtggttgc
     7741 tttttgctga ggaagagctt cttggctctc ttcagctata gtgacttttt ctgtttcttt
     7801 agaaaggtct ggctcttctt cagtagaatt agatgccttc ttttcttcta tttctgttct
     7861 cgcttcactg tcttcaggag cttcaatttt ctcttcttgc tggctttcca attcgacttc
     7921 agcttgaggg acttcctcct ctaactgagt atttttttca attggtgtat cgagatcggc
     7981 tatcgtttct tcagccttgt ctgcaacctc ttgagcttgc tcttcaggct tgttcttgct
     8041 tgttgttttt acaaaatcat tactttcaaa ccattcttgt ttcatggtag aacctccttt
     8101 ttagttagat aaatatgctt ccatagtagc agatgtaagc gtttttgtca acgtctgctt
     8161 ggtgtggata ttagatcaat attatcatca gatctcgcaa tgagttgatc cttgacatcg
     8221 gttttttcag ttttgtaagg gttgcttaat tccgtacctc ttgattcagg cttttctctt
     8281 gtgaattgga agatagaacc atagttgctt gagatgtccc agttaattcg ttggctttct
     8341 ttctggttta ggatgattct gagataatct ttggcagtca gttcaacctt gccatggact
     8401 tggatatttt cagcgtggaa gtgattctct gttgactcta gctgactatc tgtaagaact
     8461 gtatcaaaga tattaacgat attgggcgtt gtgagtttac tgtttttgat acgacttcct
     8521 tcaattcgga ggatatagct gtttgtattg agggtcgcat tttcaaggct agcatttatg
     8581 atggtggttt gtccgcgatt ggctgagatg ttgatccctt ttagagttct cccttttggt
     8641 agctggagaa taacttcttc aaaacgacta gagtagctac ttgcgatatg aagaatccca
     8701 ccaattccag aagagagaaa cggagtttca gacagtttct tatcagtgag actcagagtt
     8761 ctatcgttct gattggtgat aagatcatgg tgagcagaaa gagatggatg gtaagaaatg
     8821 tggatttgat catcgaaaga gtctgtgatg gtgagcgcgt gttggtggag agtaatttct
     8881 aggttttcga cttccttgcc aaaggttagc ttttccgtac ggctatcata gataggttct
     8941 ttggacatgg aaagtaggct tttaatcccg tcagattgga tacctacaaa aagaaggata
     9001 aagccgataa cggtagtcac cacaccaaag atgagaaatc cttttgtcca tttacgcatg
     9061 ctggttacct ctctttcttt ttttaagaac aaattgtacc aggcgaacaa tgagtagacc
     9121 gaagaagcga gctacatagg aaatgcctag taaaactagc gaagaagcac cgatagccag
     9181 taaaccagaa ccaaaaatca agataaaggc tgatttggct tgggcgagga cagtgaaact
     9241 ttcaactaaa aataggaatc cgccgatgat acccagtatg gaaactgcaa agaaagccag
     9301 aatgacagtc aaagcggcta caaggattgc gaacagggtc acgaggatgg cgattcccag
     9361 aggaatgccg ataggtgctg caaggagggc taacaaggcg atatgtaaaa tttgtcggtt
     9421 atttttttga gcgggtgctt cattgatttt tttatcgaga agattggata gaacttcgtg
     9481 ggccgcttct ttgggagttc ccaaactagc gatgagttct tcttctcctt cgactccagc
     9541 atcgtcaaag agctctctga aatagtccat ggcttcgata cggtcagctt caggtagttt
     9601 cttgagatag agttctagct gagtcaggta ttcagttctt gtcatggcgg atactccctt
     9661 ctatgatgcc attgatggtg tctgtataga gtgcccattc atcttttagg gtcaagagct
     9721 gctctatacc accgtttgtc aaggagtagt atttgcgcat gcgaccttgg aactctctag
     9781 aataggttgt cagaaagcta ttgccttcca attttttgag aatgggatag agtgtggatt
     9841 ctttgatatt agcgatcagc ttaatggttt ggctaatctc ataaccataa gaatcaccct
     9901 gctccagtac ggccaagatg agaaattcaa tcaaggcaga ggatgttgga aagtacatgg
     9961 gaaacctcct tttctaatgt gtaagatttt tatatataat ttttctacac atacattgta
    10021 catctaaaag aaagccctgt caagagaaat gtgtaaaatt tttatatata aaaaacttct
    10081 agctaaaact agaagtttaa aggatcttat ccgctctgtc cactgtaaag agggccacag
    10141 tcatcaggat atcgatgagc aagagggcag ctacagctgg tacccaagag tggaataggt
    10201 caaaactgta accaaagagg gttggcccaa aggctgctag gatatagcct cctgtttgag
    10261 ataggccgga caattgggct gtcttttcag gggcgcttgt cttgagtgaa aagttgacca
    10321 tgagataagg gaagagggcg ctggttgcgg ttccgatgag gagatggatg gcaagccagt
    10381 aaatgaaatt attgattggg aaaaagagca tggaaatgcc gaccacacca gctagtgaaa
    10441 ccagagtgag catgagctga cggttgcgag tagataaact ggttgtcagg cttgggatgg
    10501 tcattgaaaa aggaatgcta atcagagata agatagaagt cagcaagcca gcttcgtgac
    10561 tggatagacc tgcatggata gacatggtag gtaaccaggt catggcggtg taaaagatca
    10621 aggattgaaa acctgaaaag ataataattg cccaaacctg tttattacgc atgaccttta
    10681 tttgactttt ttgtttggtt tgtggagcta gtctatgatt atagcggtga tttgggagcc
    10741 agaccaaaaa agttgctaga cagagtaacg tgaggaggat aagtcctttc caagaactgg
    10801 cttgtgtaat gggcacagct agataggaag ccagagccgt tgcaatcccc atagacgtta
    10861 catataaggt ggtcagaaaa ccaattttct ttggttgatt ggcttggata agactaggaa
    10921 gcaggacatt gatgactgcg acacttgccc caaccatcaa ggttcctaga tagagcaggg
    10981 gcagattgat tagtcgaata agtgagccga tggtcaagaa gaagaggctg taggtgaaga
    11041 gatgctccaa gccgattttc tgagccagtc gggtagaaaa tggtgaaaag agggtaaaca
    11101 taaggagagg caggctggtc aagacaccaa gcgaactaac ttctacctcc agaccttgcg
    11161 aaatatttcc caaaataatg ggtaaaacag taaaaggagt tcgcaaggaa acaccaatca
    11221 ggataatacc tggaacaaaa aagagtgatt gctttttcat ataatatctc ttctagctga
    11281 ttttaataac agcttatttt aaggcttttt cactataatg tcaagtaagg tttctggctt
    11341 tcaagataaa aatggaaaag tcttgaaaat tatgatagaa tggtggaagg gaaaattcag
    11401 gagagtagta gtgactcaaa atgttgaaag tcttctcgta tccattgtaa tcagtgcata
    11461 caatgaagaa aaatatctgc ctggtctaat tgaagactta aaaaatcaaa cctatcctaa
    11521 agagaatatt gaaattctat ttataaatgc tatgtccaca gatgggacca cagctatcat
    11581 tcagcaattt ataaaagaag atgcagagtt taactcaatt agattgtata acaatcctaa
    11641 gaaaaatcaa gctagtggtt ttaacctggg agttaagcat tctgtagggg gccttatttt
    11701 aaaaattgat gctcattcaa aagttactga gagttttgta atgaacaatg tggctgttat
    11761 tcaacaaggt gaatttgtct gtggagggcc tagaccgacg attgtcaaag gaaaaggaaa
    11821 atgggcagag accttgcatc ttgttgagga aaatatgttt ggcagtagca ttgccaatta
    11881 tcgaaatagt tccgaggata gatatgtttc ttctattttt catgggatgt ataaacgaga
    11941 ggttttccag aaggttggtt tagtaaatga gcaacttggc cgaactgaag ataatgatat
    12001 tcattataga attcgagaac atggttataa aatccgctat agcccaagta ttctatctta
    12061 tcagtatatt cgaccaacat tcaagaaaat gctgcatcaa aagtattcaa atggtttgtg
    12121 gattggcttg acaagtcatg ttcagtttaa gtgtttatca ttatttcatt atgttccttg
    12181 tttatttgtt ttgagtcttg tgtttagtct agcattgtta ccgatcacat tcgtattcat
    12241 aactttacta ttaggtgcct attttctact tttatcatta ctgtcattac tcactttgct
    12301 gactttatta aaacataaaa atggatttct aattgtgatg ccctttcttt tattttccat
    12361 tcactttgct tatggccttg ggacgattgt aggtttaatt agaggattta aatggaagaa
    12421 ggagtacaag ggaacagtaa tttatttgga aaaataagcc aaataaatta aaatgtgcta
    12481 taataacaat atagtagaac tattttaagg aggagtaaat ttctatgaat aaaaaactca
    12541 cagattatgt gattgatctg gtggaaattt taaataaaca acaaaagcag gttttctggg
    12601 gaatatttga tattttcagt atggtggttt ccatcattgt atcttatatt ttattttatg
    12661 ggctgattaa tccagcacct gttgactaca ttatctatac gagtttggcc ttcctgttct
    12721 atcaattgat ggttgatttt tggggcttga gcgcgagtat tagtcgttac agcaagatta
    12781 cggatttcat gaaaatcttt tttggtgtga ctgctagcag tgtcttgtca tatagtatct
    12841 gttatgcctt cttgccactc ttctccatcc gttttatcat tctctttatc ttgttgagtg
    12901 ccttcttgat tttattgcca cggattactt ggcagttaat ctactccaga cgcaaaaaag
    12961 gtagtggtga tggagaacac cgtcggacct tcttgattgg tgccggtgat ggtggggctc
    13021 tctttatgga tagttaccaa catccaacca gtgaattaga actggtcggt attttggata
    13081 aggattctaa gaaaaagggt caaaaacttg gtggtattcc tgttttgggc tcttatgaca
    13141 atctgcctga attagccaaa cgccatcaaa tcgagcgtgt catcgttgcg attccgtcgc
    13201 tggatccgtc agaatatgag cgtatcttgc agatgtgtaa taagctgggt gtcaaatgtt
    13261 acaagatgcc taaggttgaa actgttgttc agggccttca ccaagcaggt actggcttcc
    13321 aaaaaattga tattacggac cttttgggtc gtcaggaaat ccgtcttgac gaatcgcgtc
    13381 tgggtgcaga actgacaggt aagaccatct tagtcacagg agctggaggt tcaatcggtt
    13441 ctgaaatctg tcgtcaagtt agtcgcttca atcctgaacg cattgtcttg ctcggtcatg
    13501 gggaaaactc aatctacctt gtttatcatg aattgattcg taagttccaa gggattgatt
    13561 atgtacctgt gattgcggac attcaagact atgatcgttt gttgcaagtc tttgagcagt
    13621 acaaacctgc tattgtttat catgcggcag cccacaagca tgttcctatg atggagcgca
    13681 atccaaaaga agccttcaaa aacaatatcc gtggaactta caatgttgct agagccgttg
    13741 atgaagccaa ggtgcctaag atggttatga tttcgacaga taaggcagtc aatccaccaa
    13801 atgttatggg agcaaccaag cgcgtggcgg agttgattgt cactggcttt aaccaacgta
    13861 gccaatcaac ctactgtgca gttcgttttg ggaatgttct tggtagccgt ggtagtgtca
    13921 ttccagtctt tgaacgtcag attgctgaag gtgggcctgt aacggtgaca gacttccgca
    13981 tgacccgtta ctttatgacc attccagaag ctagccgtct ggttatccat gctggtgctt
    14041 atgccaaaga tggggaagtc tttatccttg atatgggcaa accagtcaag atttatgact
    14101 tggccaagaa gatggtgctt ctaagtggcc acactgaaag tgaaattcca atcgttgaag
    14161 ttggaatccg cccaggtgaa aaactctacg aagaactctt ggtatcaacc gaactcgttg
    14221 ataatcaagt tatggataag attttcgttg gtaaggttaa tgtcatgcct ttagaatcca
    14281 tcaatcaaaa gattggagag ttccgcactc tcagtggaga tgagttgaag caagctatta
    14341 tcgcctttgc taatcaaaca acccacattg aataaaaaag aaaaacgcat attatcaagt
    14401 taaataacct tggtaatatg cgttttatta tgtagagact tatactcttc gaaaatctct
    14461 tcaaatcacg tcaacgtcgc cttgccgtat atggttactg acttcgtcag ttctatccac
    14521 aacctcaaaa cagtgttttg agctgacttc gtcagttcca tctacaacct taaaacagtg
    14581 ttttgagcag cccgcagcta gtttcctagt ttgctctttg attttcattg agtattactt
    14641 cattttcttc tgaaatagag ttgtcgccca gtctatgcta ttgaaaatac gccaaaactt
    14701 ctaagggttt gtgagcgata taatcaggtt gatagtttag tagatctgct tgctctccaa
    14761 atccccaagt gacggccaat ttctgaatac ctgtttctcg agctcccagc atatcaaact
    14821 tggtatctcc gatgatgatg gcttgttctg gtgctagttg atgtgtctgt aaggcttggt
    14881 gaatgacatc tgccttatgg ggtgcttcag ggctagaacc ataaatacca tcaaagaaat
    14941 gatggatttc caagtttttg gccatgtctt gagcagtaga tgtattcttt gtcgtggtga
    15001 tgtagagtgg ataactgctc gataactcct caagcaagtc tataatctga ggaaagagtt
    15061 gagcttcata gatgcctttt gccttatagt aagaacgata tatctgcatg gcttcagaaa
    15121 tttggtcttt ggacaggcag gtcgcaaaac tactttcgag aggtggtccc ataaaaccac
    15181 gaatagtttt ggcatcaggg ctaggcaccc ccagctcttt aaaagtatag gtaaaggcat
    15241 tgtgaatccc gatagaacta tcaacgaggg ttccatccaa atcgaaaaaa atcgctgtga
    15301 tagaggtcat ggtttctcct atttgataag cttattctcc gaaaatctct ttttggaggc
    15361 gacgaccagt aggggtggta gcgagtccac cttcagctgt ttcacgaaag gcagttggca
    15421 tgcttgctcc tacttggtac atggcatcga tcacttcatc cacagggatt ttagattcga
    15481 tacctgccaa ggccatgtct gctgcgatga aagcaaagct agctcccatg gcattacgtt
    15541 tgacacaggg aacttcgacc aaacctgcaa cagggtcaca gatgaggcct agcatatttt
    15601 taatgacaaa ggcaatagct tgactggcct gataaggtgt tccacctgca gccagagtca
    15661 aggcggcagc actcatagca gaggctgaac caacttcagc ttgacaccca ccctcagcac
    15721 ctgagatgga ggcattgttt gcgatgacta gtccaaaggc accagcagca aagaggaaat
    15781 ccaattgttg ctcgtggctg aggtctaatt tttcaatagc agcagtgaga acggaaggga
    15841 gacaaccggc acttcctgcg gtaggagtag cgcagaccaa gcccatttta gcattgtgtt
    15901 cattgactgc gatagcattt cgggcagcag agagaatcgt gtaatctgat aaagtttttt
    15961 cgtttttgat gtagtgatcc aatttggcag catctccacc tgtcaggcca ctacgagatt
    16021 tattttcatt gaggccaagt tggacagagg ctttcataac ttccagattg cgttccatga
    16081 gaaggaagac ttcttcacgt tcgcgaccgg tcaattcaaa ctctgttgta atcatgagtt
    16141 ctgcgacatt tccttgaaag tccagatctg cttgctcgac caattctttg atagaataaa
    16201 acatgcttcc tcctatttaa agaaattgac attgtggaga tgagggattt ttcgaatttc
    16261 ttcgatagcc tcatcacagt tgcgactgtc aacttcgata atcataatgg ctttttcacc
    16321 agctttttca cgagtgacat tcatctgggc gatattgata ccatagcggg aaagcgcctc
    16381 tgtaacaagg gcaatcatac ctggaatatc ttgatgaacg atgatgatag tcggtgtatt
    16441 catattgaga gagacggcaa aaccattgag ttcggttacc tgaatatttc ctccaccgat
    16501 agaaatacca gtcacgctga tggtcttgtg ggcattttta acagtaattt tagtggtgtt
    16561 agggtgaggg gcattgctgt ctttctgaat ggtccagaca atcttgatac cacgcttgtg
    16621 ggcaatttcc agactatttg gaatttcagg atcatctgta tccattccta aaatacctgc
    16681 aacaagggct aggtctgttc cgtgaccacg ataggtcttg gcaaatgagt taaaaagttg
    16741 gaattcaact tctgtcggag tatcatcaaa aatggaagag acaatcttcc caatacgaac
    16801 agcaccagcg gtatggctac tagatgggcc aatcataact ggtccgatga tatcaaagac
    16861 agattgaaaa cgaagtgatt tcatcagttt ccccttataa aaattcttat ctctattata
    16921 tcaaagaatg aggggcttgg ctttaattgt ggatgaaaac ctttctaata cctcaaatag
    16981 cataaaaata gtatctttta tgacaaaaaa caccttattt agggaaataa aaaataattt
    17041 tgtaatattt ctacataaaa gtgtcaagaa acggtaatat ttaaagggta tgatagaact
    17101 atagaaagaa ggagaatttt cgaatatgaa atcaataact aaaaagatta aagcaactct
    17161 tgcaggagta gctgccttgt ttgcagtatt ttctccatca tttgtatctg ctcaagaatc
    17221 atcaacttac actgttaaag aaggtgatac actttcagaa atcgctgaaa ctcacaacac
    17281 aacagttgaa aaattggcag aaaacaacca cattgataac attcatttga tttatgttga
    17341 tcaagagttg gttatcgatg gccctgtagc gcctgttgca acaccagcgc cagctactta
    17401 tgcggcacca gccgctcaag atgaaactgt ttcagctcca gtagtaagtg aaacagttgt
    17461 ttcaactgta agcggatctg aagcagaagc caaagaatgg atcgctcaaa aagaatcagg
    17521 tggtagctat acagctacaa atggacgtta tatcggacgt taccaattaa cagattcata
    17581 cctgaacggt gactactcag ctgaaaacca agaacgtgta gcagatgcct acgttgcagg
    17641 acgttacggt tcatggactg ctgctaaaaa cttctggctt aacaatggct ggtattaaga
    17701 actaacgaac aaataatatg taaagagtcg aggaaatccc tcggcttttt tatctttcct
    17761 tcgcttggta atagatctct acttcttttt tgagatgaga cagcatagaa gtttcctcgg
    17821 ttagctccag aagggagaac cctttttgga taagtttaga atcgtctgta caaatcccaa
    17881 tacggacata gcagatagcc agcctatcgt agcttttctt attcttggcg tcctctagta
    17941 aagtgtagca gatttgctta cacatgtttt tatcttgatt gtatagatag agtgtggaaa
    18001 ggttgagcag gattgctatt tgcaagtcat ataaatgttg atagttttta tagacttcta
    18061 agcgttgcaa gattttctcg gattattgac aaataaacgg acattctgat agacgattgc
    18121 cctagcggct tagtgtaaac tttacaaatt tggcttgtaa tttttttata aaattcactt
    18181 cagttacttg acagttatta tattttcact tattatatag ataaaaggat gagatgggag
    18241 tttaaaaatt tgaaagcgct atccatattg tttattggac tgattcttga gtaatagtta
    18301 gagtgtgctt aatactactc tggttgttca aggacctgat acagaagcgc accattctct
    18361 cggttaagag taagttcgtt gttaaaaaat gaaatgagat agaaggaagg tgagtccaat
    18421 ggactacgat acttgttgat aaattactat agctgttttt acggaagagc tctcgataat
    18481 aggagaaata aatcatgaga aaattagtta aaattggtgt tgcatcttta atggtatgta
    18541 gtatacttgc ttctacaagt gttttggcag tatgggttga tggtggtcaa tggaactatg
    18601 gagtaggatg gtcaggaaat tttggttatt ctgattattt acattctact cgctctcata
    18661 cagcaactgt taaagatgga aataaattct ctaaggatcg tgcagaagct gaggcatggg
    18721 ctcgggcttc aatcttcaaa ttcccaccaa cgggaatgga atatttctat ggattttaat
    18781 taaaattctc cctccccttt tggagaggga gtttcttcac gggaggtatc tctatgaaaa
    18841 aaatcagtca tctttgtatg ttactcctgc ttctgtgtac cacttttttt gtttttaatg
    18901 taaactatac acgagaagtg gttcggattc aagaaatggg aaagactgta gattctttgg
    18961 atttgtattt gaaagatatt aacgaacctg cagcgtctgt tcttcgattt tttgaggatg
    19021 tatcaaagga gtataaagtc tccatcatca aaacagacag tggtgatgag gtggtcaagt
    19081 ctggtgtttt tgataaagat accttcccct accaagagtt tgggatttct tctcttgatt
    19141 ttaccacaga tggtgaagga gtctatagta ataaagaaat ttccaataaa cttggtacga
    19201 ttccgacctt tctaaaagcc aaacctattc agcttatgac ttttcaaacc tatatcaagg
    19261 atacatctcg tagtttaaat ggtcgctata cgataacttc tacacaagag atggacaagg
    19321 ataggattgt acagaaatgg agcgattttt tcaagataga ccaggctacc ttgctagagc
    19381 cgacctacaa aagtgcagtg gaagtcataa atcgagattt gcttttatct gccattgttt
    19441 ttgtcttggc tattttgctt cttgtgttag tgacagtgta tcaaccgatg atggagatga
    19501 aaagagttgg ggtacaaaaa ttacttggtt ttcaagatag ggctgtttta gctgatgttg
    19561 taaaaggcaa cctttacctc ctcctaggtg gggctcttgt gatcaatcta ggcgtgtttt
    19621 tcttgcttga ttataagcca aaagatttgt ttcctatgct gtggttgtct cattttttgc
    19681 tgttgcagct ttatctcttt atcagttggt tgacttacct cttaatccaa aaaatgacaa
    19741 tcagctctct gctgaaaggt ttttcatctt tcaaatttgg tctactcttt aattatttga
    19801 tgaaaattgg aactaccatt ttactgacag tcttgctagt tggggtagga aaaagtttgg
    19861 agcaagaaaa caaagagttg gattaccaga aacagtggat cagccaagga aattatctga
    19921 ccttagaaac tttccaactc aatgataact tgtggcaaga gcagttggca ggctcaggga
    19981 aggcattgga ttatttctat cgattttatc aggatttggt agaaaaaacg caggcgggct
    20041 atgtgcagag tagcagtctt cctgtaaaaa attttgtcca atcagaacag attcagcaat
    20101 atcagttaac agatacggtg gatgtttact atgccaatcg caattttcta aagagcaagg
    20161 gattcaagct accagatacc ggtattaaaa aagttatttt gatgccagca agtacgaaag
    20221 gtgaagaaga taaaaatcag ctcttgggga agttaattgc ctttcattcg atgaagtatg
    20281 aagagcagca aaaacgaacg atagaggaga tggatgtcga gattgcctat tatgaaggag
    20341 attggtcatt tttcccatat agtgataagc gaaaggaaaa tctctccaat ccaattatta
    20401 gcttggtcaa tgattctgat atgatgtggg atgagaaagc ctccctgtca acaactggct
    20461 taaataatcc gattaaaatt gaaaatacgg ttcaacatca aaaagagatt acagagttag
    20521 ttgagaaatt gtcagatgga aattatttaa aattttcatc tattcaagcc attcaacaag
    20581 agaaagtgga ttcttatcga gatgctgttc ggaattttaa cctactcttt gctttgtttg
    20641 gtctccttag catgatgatt tcctacttct tactagtaat aactttctta ttgaagcgca
    20701 gggatatcat taccaagaag tttatggggt ggaaactggt cgatcgctac cgtcctctcc
    20761 tcgttctgct cttgctgggc tatagtttcc ctcttctagt cttgattttc tttgcccatg
    20821 cgttcttgcc acttctgctg tttgcaggct ttacatgttt ggatatacta tttgtgctag
    20881 tcttggcttc taggatggag aaaagaagtc tagtagagtt attgaaaggg ggcatcttat
    20941 gattgagttg gaaaatatta ccaaaaccat tgggggaaaa gtgattttgg atcacttgtc
    21001 tctcaggatt gatcaggggg atttggtagc tattgttgga aaaagtggta gtgggaagtc
    21061 gaccttgtta aatttattag gtttgataga tggtgattat agtggacggt atgagatttt
    21121 tggtcagaca aatctagcgg tcaattctgc taagtcgcaa acaataatcc gtgaacatat
    21181 ctcttatctg tttcaaaatt ttgccctgat tgatgatgaa acggtcgagt acaatctcat
    21241 gctggcgctg aaatatgtga aattgtctaa gaaagacaag ctcaaaaagg tggaagagat
    21301 tttagagaga gtaggtttgt catctacttt gcatcaaaag gtttccgagt tgtctggtgg
    21361 cgaacaacaa cgaattgcag ttgctagagc catcttaaaa cccagccagc tgattttagc
    21421 cgatgaacca acaggttcgc tagatcctga aaatagagat ttggtcttga agtttctctt
    21481 agagatgaat cgcgagggga aaacagtcat tattgtgacc cacgatgctt atgtagccca
    21541 acaatgtcat cggatcattg aattgggcga ggggaaatga gtttgttcag ctctttttga
    21601 ctgactgaat actcatgttt ttcagagagg aatagcataa atacgcctag aaatgacatt
    21661 tttatgtagt atttctaggt ttttttgttt caaattgaaa atttttccaa tttaggcttg
    21721 acaaaggatg aagataggtg tattatttat acaaccaaaa agaataaaca taaaggagac
    21781 tttgttatga ataagatgaa gaaggtgttg atgacgatgt ttggtttagt gatgctcccc
    21841 ctactatttg cttgtagcaa caatcaatcg gctggaattg aagccatcaa gtccaaagga
    21901 aaattggttg tagccctcaa tccagatttt gctccatttg aataccaaaa agtggttgat
    21961 gggaaaaatc agattgtggg ttcagatatc gaattagcca aggctatcgc aacagaacta
    22021 ggtgtcgaat tggaactatc tcccatgagt tttgataatg tactggctag tgttcaatca
    22081 ggaaaagccg accttgccat atcaggtgtt tctaagacag atgaacggag caaggtgttt
    22141 gacttttcca ttccctacta tactgcaaaa aataaactca ttgtcaaaaa atctgacttg
    22201 actacttatc agtctgtaaa cgacttggcg cagaaaaagg ttggagcgca gaaaggttcg
    22261 attcaagaga cgatggcgaa agatttgcta caaaattctt ccctcgtatc tctgcctaaa
    22321 aatgggaatt taatcacaga tttaaaatca ggacaagtgg atgccgttat ctttgaagaa
    22381 cctgtttcca agggatttgt ggaaaataat cctgatttag caatcgcaga cctcaatttt
    22441 gaaaaagagc aagatgattc ctacgcggta gccatgaaaa aagatagcaa ggaattgaaa
    22501 gaggcagtcg ataaaaccat tcaaaagttg aaggagtctg gggaattaga caaactcatt
    22561 gaggatgcct ttaaagcatc cattgaaaaa tagaaagaag gaaaagaaca tgagtaaaga
    22621 aaaagtaatt ttggcctatt ctggcggttt ggacacatca gttgctatta cctggttaaa
    22681 gaaagactat gatgttgttt cagtttgtat ggatgtgggt gaagggaaag acttagactt
    22741 catccatgat aaggctctca aggttggggc agtcgaatct tatgtcattg atgtcaagga
    22801 cgaatttgct acagattatg tgctagtggc tcttcagtca catgcctatt atgaacaaaa
    22861 gtaccccttg gtatctgcct tgagccgccc tcttatttct aaaaaattag ttgaaatagc
    22921 gcatcagaca ggagcgacta caattgctca tggctgtacc ggtaagggga atgaccaagt
    22981 cgaataccag attgcagtcg ctaagaaagc gaatgaagct aaaaagtgat ggagtgatgg
    23041 gttcagaata agaggttggt cgattggtag cctctttctt gtcgttgaaa aagtgagata
    23101 tattgacttt tgaaaaaaat gtcataattg agttgggata aacgtaaaag tcatactttc
    23161 tcgttaaatc gttcggcgat tcatggtgac atggacacat agtagtaaac acactatgtg
    23221 gcttggcaga gctaaaaact tctggcttaa caatggctgg tattaagaac taacgaacaa
    23281 ataatatgta aagagtcgag gaaatccctc gacttttttt ataatttctt tggttgataa
    23341 tgggtctcta cttctttttt gagatgagac agcatagaag tttcctcggt cagctctagg
    23401 agtgagaacc ctttttggat aagtttagaa tcgtctgtac aaatcccaat acggacatag
    23461 cagatagcca gcctatcgta gcttttctta ttcttggcgt cctctagtaa agtgtagcag
    23521 atttgcttac acatgttttt atcttgattg tatagataga gtgtggaaag gttgagcagg
    23581 attgctattc gcaagtcata taaatgttga tagtttttat agacttctaa gcgttgcaag
    23641 attttctcgg attattgaca aataaacgga cattctgata gacgattgcc ctagcggctt
    23701 agtgtaaact ttacaaattt ggcttgtaat ttttttataa aattcacttc agatacttga
    23761 cagttattat attttcgctt atgcttatta tatagataaa aggacgggat aggagtttaa
    23821 aaatttgaaa gcgctatcca taataataac gcataatttt ctccttttcg tgaaaaaagt
    23881 taacgtaatt ttaaaatgag cttaataaga ggtactatgt aggtagaaaa taaagatagg
    23941 agaaaaagta tgaataaaaa aatattttgt attctggtat gtattatatc attgattagt
    24001 ctagctataa tctttccatg gggctggtcg atataatgta agggagcttg agttgttagt
    24061 ggaggataaa atgttaagag taatagtagt tattcaatct ttagtaataa tactgcttgc
    24121 tgttgcttta ttattatctc ggaaaaactt tgattcgtta aatgttgttc ttataatgat
    24181 gatcgtatca caattgttgt tattagtata tttgataaaa tcagggaatc agtgattagc
    24241 tgttatttga attaagtaaa ctgttaagct tcaagcagta actggtttta aatatttaaa
    24301 ataagataaa ggaaggaagt ctaatttagg taactaaaca aagcctgcga tcacttgtta
    24361 ggaaactatc ctaaccatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
    24421 aataattatg ttgctcttga gcaagaagag atgatgtatc ttgatggggg tggtgttggt
    24481 cgtaactggt ggaatagtag aggtagtttt gcaacagttt tggatgtagg tttggccatc
    24541 tatagtggtg gtgcaacaat ttattctgct tatgcgataa aaaaagctat ctcagctaat
    24601 agaggggcta ttacgagaac attacgtagt ttaataatta aacatgtagg tagtgcagct
    24661 ggccatttag tcaatactgc actaaacgtt gcactaactg ttactggatt ttcactaggt
    24721 ggagcaatcg catatggggc tgattgggct gacggtagct tagatggtta tatttttgct
    24781 taaaatgaaa catttttttg caggaattgg tgaaattcat tttttgttat ttttattata
    24841 tctaagcatg tctgctagtc caattattgg actagtgatt ggatatacta aaataaatct
    24901 aataaattct attattatag ctcttggtat gatattggca ttaattttgg tattatcaag
    24961 agtgtataga aaatattttt atagagacga tgatgactaa agtttttatc aataatttgg
    25021 gctccttgtc aactgtagtg ggttgaagaa aagctaacgt ctggggaagg ggttaaagct
    25081 ttgctttatc aaatattgac ttacagagtt gctctattgt attgatgtat tcttagtaaa
    25141 taatatggtg ttttgaatga aagatgatca gaaatattta ttagcgggac tttattcgct
    25201 tctagttgca atattttatt ttccattgat tgagtccaag gggatttttg taagtatatt
    25261 gatggcggtt ttacttttat atttaatata cttcattgga acagtcattc atattgtgat
    25321 aattaagttt ataagaaaaa aatcttttaa gtatttggtt ctatatccat ttacttatga
    25381 tgggagctgg agatttcaac ctataaactt actctacttt ccagaaatgg tgagagatgt
    25441 cattccgatt aatttagttc aagaatattg ccaaggacaa ccttacgggc tgttaaaaaa
    25501 gatgctgaaa agaattcgat tgtcacgaga gatagcttta ctcctggcta ccattatcgt
    25561 ctattttttt acgcatagaa ttctacctct ttcagtattt acgttcatgt tttcttacat
    25621 attgatattt gcacaatctt atttgggtgg taatactgct tggattggaa atagaagatt
    25681 aataatagat gatgaatttg aaaaaatctt gctttcaaaa agttatataa aagaaatatc
    25741 atctgcacga tactcggaat acttgacatg tgaatacaaa aaccttacac caatcatatt
    25801 gttagctatt tttgaaaatt tacttgactc ctacttgctt cagaatcaga gtgaggttga
    25861 cttagatatt ttttataaag ttttaccttt gctttataaa gaaaaatata ctatgggatt
    25921 caattacttt gtaagtttaa attatttact atataaggtt ggatttttgg gaatcattta
    25981 cgataatgaa gcattaggag atttgtcaaa acaatattta aacagaaata tttcggaatt
    26041 acaagatggt tctttcgagg gcggtataca agatgctgtt gcctctaaac aaatagtagt
    26101 tataaatgaa tttatagctt gtttaaattc cagatgcatg ccatcccaat atgatagatt
    26161 tttttataaa gatagacctt atattttttc cagaaagagt cctattaaga ggtgaaaatt
    26221 tgttacattt ggattaacaa gtgtcctagg gattagaaat aactctagta tagctagata
    26281 tttttgagta actagaaata tcattaggct acccatatga ttgccagaaa agatggctga
    26341 tgaatcttat ttatactgtt gcagtaggcg ttgtctagga taaataagct atcttgatgg
    26401 gggagattgg aataatttta gtagaaacat taaaggatta tgggcaagta gcacaggatt
    26461 aggtgatgca atgtgctaag ttggcttggt gttagcagta gtattattta acaatggaaa
    26521 gtagactaaa tgaaaaataa acgttatttt tttgacacaa ttttaatgat tttactactt
    26581 ataagcacga tattttgtgt cagcccagta tttataaaat tggacatctt aggaactccc
    26641 tctcatgcca tcttaacctt tgtattggcg ataccgttat tctatatttt gtctcaatgc
    26701 ttacatactt tgctattact agtttcctca atcttttgta aattaagacc aatttatttt
    26761 tattttatat ttgtgatcat tataggagct aggaaatact atcgaattct ctttcaccaa
    26821 ctaatgggat ttagtccagg aatagcagtg ttttataagg agagtcaaac aactaagaat
    26881 ctgtttaaat tttactactt cttgtacttt acaacactaa tttcatacta ttttttcttt
    26941 acttttgtgt atgacaaacc gttgcttttg cctcttattc cattttctat tatcatagca
    27001 ttagtacaaa aactttatag aattgagaat cagcaattat ttctgttaaa atcaaaggta
    27061 ctaacaatac tggaatctaa gaagaattgt gagtttaatc ttcaggatta tcatgaaatt
    27121 tggaaattgc aatcaaaatc tgagttgcca tgcgtggctt tatcttatat cagtttgatc
    27181 aagccatatc tttcagagag cgtgcgtgaa caaattgatt tattagaagt taagcgattt
    27241 aaaaaaataa atcatccaat atcactttat ggtatgttgg atgttataaa attaaatcta
    27301 tatttacggc attataatga aaaaataaat atgaatcaat gttaaagaaa attttagagg
    27361 taagaccaga ctttgtttta atcgagcaga atattgatga tagtttaaat agctcgcaac
    27421 cattatcttt atctttagct atttcagaaa tccaactttt gcttgaagtg tatataggga
    27481 tcaaacatgt ttcaattagg agataaaact agaataacat ttgctattat aggggcaagt
    27541 tgcatattag tcagtatgta tcttatacct ctcattaaca cggataataa attttgggaa
    27601 atacttttat ttataatagg tgtattgcta attggaattg cgttactaag tcaaaaaaaa
    27661 taaattttga aatagtatta gtgagttcgc aatcatttat tgctagtggt ttagaactgt
    27721 taagtttcaa gcaataattg gttttaaacc ttaggtaacc tataaaaaca aataaggtag
    27781 agaaaggata tcttatttag gtaactaagt actataaaca cagtcgacaa tcacttgtta
    27841 ggaaaccatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact cgtattacca
    27901 aataattatg ttgctcttga gcaagaagag atgatgtatt ttgatggggg attttctatt
    27961 ccgagatggc ctgttgcaac agccattaat atagctttta atgatgtctt aggtggagga
    28021 gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt tacaagcgca
    28081 attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt agcaggattt
    28141 gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcaatgc tattacaaca
    28201 atctgggcca ataatgatgt aaataggaga gacccaaatt taaacgcctt gtggtaacta
    28261 gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg tctatttata
    28321 tcatccataa cttttttagc ctatgatttt gttagcgaag aaataaaaaa gttgattatt
    28381 tggatgaatg tcgttttttt gattttaatc atagcaatga taatttatcc aaaattaaga
    28441 aaatgataag gacactgtaa aattatgata cgtaaactaa tcattttttt attaatgctc
    28501 cctctttttg tcttgtggct agagttgcat gtcctagtga ataacttact attgaatcta
    28561 gaatctcccc ttgattttgt gattagtatg agtcttgctt tctgtagttt gattttatca
    28621 aaaatagttt tagacatact atacgcattg aaagatttgt acaagaaaga agctcttatt
    28681 acgatttttc cttttatttt tataggcagg aagaaagtaa atgtgaggtt ctcgccctat
    28741 ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat tatatggagt
    28801 tttattcttg aaattgctat tatcctagta tttattttaa aaattccttt tgcaatcatc
    28861 atgcttacta caatattttt ctggactata atggatatca atcatctcgt ttttaataag
    28921 acggaatttc tttttaatca aaacaaatgg caaaaagaag attcgtttga aagtgatttg
    28981 acgaaaacgt taaaggataa gatacaaaaa tcagagctaa gttattctga cttaatgtct
    29041 cttcagctgt atgatgcgat gaaccaatcc acctttttaa cggatagtga actttttgag
    29101 gatattttga aaaaaatcga agattctcat aacacccttc tgtgtacagg tcttgtcgag
    29161 ttactgctgt atgaaatttc tattagtaac aataacaact ggcaagaaaa ggttgataaa
    29221 attagaatac agctcatcag aatcaatcaa ttagattttt tctattatac aagttggtta
    29281 aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc tcggaaatta
    29341 ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa tgaaacaatt
    29401 tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg ttgtgattga
    29461 tgaagaagaa atgatgtatc ttgatgggga agcttattta agcaagcgtg cttgtcaagg
    29521 aatttgcgca gctttagcta tgagttcagg aacttttata gcattagctg gagctgcagt
    29581 tttaaccaaa aaactaataa actatattaa ggttggaggt cttggaggct ggcttattgg
    29641 tgcagcagca ggtgtattgg ctacagcagc agggaaaata gcttactata ttggatatgg
    29701 tgttcttaat agaggttgtg atattaacgg gaacccttat ccttgggatg gattcatatc
    29761 tgcgacagta aaatgagtaa tgtagataag attcgaaaaa tacacattat cgtatgttgg
    29821 atgtatatat ttttatcatt cagggcgatt ataaatgaca cggagtattt tttgcttatt
    29881 tttttagctt ttatctactc aatagtatca ctacctctat attctgtgaa aaataaaata
    29941 gtatctatct gtctagccat aaattcgatt ctgttaatga gtttccccat tttaatcaat
    30001 aagtttttcc cagaaagttt tttgacttat accgtattaa taagtgtttt tattacagag
    30061 ttgataattt ttcatttaat tgggaaagat tttgatatta aattgactaa cgaatataag
    30121 aaaattagtc agtttagaag caaggtgtct caatctcctt ggataaaata tttagagatt
    30181 tctagtttta tattaactat atttccatct attctttatg gtacagttga taatcatgta
    30241 ctgactctta tctttttgat aaaaatttgt gcagatacca cgataaaatt tttattcatc
    30301 agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt cgcattggat
    30361 gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg ctatttgttt
    30421 tcggttttac ttcttttttc taatttttca gttccattta tcaaagaaaa ggaattcgaa
    30481 ttatttaaaa atagcaagta atagaaacat aggttaaatc ttagaacggc ttaaaatcag
    30541 atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac aatcgaggat
    30601 cacttgttag gattacattt taatcatgct taataagaat ggagaattcc tatggggatt
    30661 gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctatt ctaggtttag
    30721 aatccttcag aatgtaaaat tttaagcagt caaagactta gaatagcccg aaaacattta
    30781 ttttatagca attctaggct tagaattgct catatatatg tatttgagct gctcgatagt
    30841 taggatagct ctattctgag aaatctgagc tatcaatgct tcagaatagt attcgccaat
    30901 ggtttttatt gaagaggtga ttgttttatg atagtctaaa ataaaactga tttaatagag
    30961 taaatggaga atcgttacat gaaacatttt tttgcaggaa ttggtgagat aaaacttgtt
    31021 ggctacttat tgtatatatg tgtaggacta gctcctcttt ttcatatata tgtcataggt
    31081 tcggaactga gttttgtgaa aatagtgtta tctattttgg gagttatatt tgtaagtatg
    31141 ttaactattg ctcgaattta tcggactttt ctataaagaa tagtttggac ttgaactgta
    31201 tctaaaaaca gaggttggtc gattatcagc ctctttcttg tcgttgaaaa gagtgagata
    31261 tattgacttt tgaaaaaaga tgtcataatt gagttgggat aaatctaaaa ataatatagt
    31321 agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat taatttgact
    31381 ttcctaatcg atttgttcat atcttgtttc aatctactat actttctcgt taaaccgttc
    31441 ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt ggcagatcta
    31501 aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga gaagccgact
    31561 ctaatcaacc actttgggca gtagtgagaa ctgccccgtg ctttttattt tgagaaaata
    31621 tggagtttgt cgttgaaatt acttgattgt attttggatt atcaagaaag attcaatgga
    31681 aaaacatgtc aagtatcaac gaattataag tatttagaga ctttcaaagt gaatttttgc
    31741 ttgactgatt tacatcattt atttgactta cacaaaatca cacgagatta tgctagtcaa
    31801 acaaaacctg ctattcaagc tggtgttttt attttagaag attttagaaa tatcctatgt
    31861 acaatgatgt aatcgaaagg atatctttat gtgagtttat cggcgatatc ttctatatct
    31921 aagctagcaa gttgttgcat cgtagctaag gatttatcta aaaatactat gaaattggac
    31981 gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg aagagacaaa
    32041 agcggagtat ttaaaccagt tactctacat tttacaagcg ctaagaaata tgctaaagtt
    32101 cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg cttaagcttg
    32161 cgttttttgt tgtttaacga aattaaaaaa caagctctct catcggaaat gtttttatag
    32221 gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa agtagtgtct
    32281 ttatcttttt ggagtagaag cttatgatat agaaatttgt aataaaaatg taatataaaa
    32341 catttgacaa atatttacgg ggggagtata cttaatataa gtatagtcta aaaatgacta
    32401 tcagaaaaga ggtaaattta gatgaataag aaaaaaatga ttttaacaag tctagccagc
    32461 gtcgctatct taggggctgg ttttgttgcg tctcagccta ctgttgtaag agcagaagaa
    32521 gcccccgtag ctagtcagtc taaagctgaa aaagactatg atgcagcgaa gagagacgct
    32581 gagaatgcga aaaaagcttt agaagaagca aaacgtgcgc agaaaaaata tgaggatgat
    32641 cagaagaaaa ctgaggagaa agcgaaaaaa gagaaagaag cttctaaaga ggaacaagct
    32701 gcaaatctga aatatcaaca agagttggtt aaatatgcta gtgaaaaaga ttcagtaaaa
    32761 aaagctaaaa ttctgaaaga agtggaggaa gctgagaaag agcataagaa aaaacgagca
    32821 gaatttgaga aagttagatc agaggtaatt cctagcgcgg aagagttaaa aaagactaga
    32881 caaaaagcag aagaggctaa agcaaaagaa gcagaactta ttaaaaaagt agaagaagct
    32941 gagaaaaaag ttactgaagc caaacaaaaa ttggatgctg aacgtgctaa agaagttgct
    33001 cttcaagcca aaatcgctga gttggaaaat gaagtttata gactagaaac agaactcaaa
    33061 gggattgatg aatctgactc agaagattat gttaaagaag gtctccgtgc tcctcttcaa
    33121 tctgaattgg atgccaaacg aactaaacta tcaacacttg aagagttgag tgataagatt
    33181 gatgagttag acgctgaaat tgcaaaactt gaaaaaaatg tagaatattt caaaaaaacc
    33241 gatgctgagc aaactgaaca ataccttgct gcagctgaaa aagacttagc tgataaaaaa
    33301 gctgaattgg agaaaactga agctgacctt aagaaagcag ttaatgagcc agaaaaacca
    33361 gctgaagaaa ctccagctcc agcaccaaaa ccagagcaac cagctgaaca accaaaacca
    33421 gcgccggctc ctcaaccagc tccagcacca aaaccagaaa aaacagatga tcaacaagct
    33481 gaagaagact atgctcgtag atcagaagaa gaatataacc gcttgcccca acagcaaccg
    33541 ccaaaagcag aaaaaccagc tccagcacca aaaccagagc aaccagttcc tgcaccaaaa
    33601 acaggctgga aacaagaaaa cggtatgtgg tacttctaca atactgatgg ttcaatggcg
    33661 acaggatggc tcca
//
LOCUS       DAVBOU010000021        33134 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBOU010000021 DAVBOU010000000
VERSION     DAVBOU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.021"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(271..558)
                     /locus_tag="VQ879_001067"
     CDS             complement(271..558)
                     /locus_tag="VQ879_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143230.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(568..978)
                     /locus_tag="VQ879_001068"
     CDS             complement(568..978)
                     /locus_tag="VQ879_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3143231.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1046..1777
                     /locus_tag="VQ879_001069"
     CDS             1046..1777
                     /locus_tag="VQ879_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143232.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1774..2823
                     /locus_tag="VQ879_001070"
     CDS             1774..2823
                     /locus_tag="VQ879_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143233.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPMDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(2991..3320)
                     /locus_tag="VQ879_001071"
     CDS             complement(2991..3320)
                     /locus_tag="VQ879_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3143234.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3597..3935
                     /locus_tag="VQ879_001072"
     CDS             3597..3935
                     /locus_tag="VQ879_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143235.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3940..4677
                     /locus_tag="VQ879_001073"
     CDS             3940..4677
                     /locus_tag="VQ879_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143236.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4691..6031
                     /locus_tag="VQ879_001074"
     CDS             4691..6031
                     /locus_tag="VQ879_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3143237.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6075..6230)
                     /gene="blpC"
                     /locus_tag="VQ879_001075"
     CDS             complement(6075..6230)
                     /gene="blpC"
                     /locus_tag="VQ879_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3143238.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6287..7648)
                     /locus_tag="VQ879_001076"
     CDS             complement(6287..7648)
                     /locus_tag="VQ879_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3143239.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7659..9812)
                     /gene="blpA"
                     /locus_tag="VQ879_001077"
     CDS             complement(7659..9812)
                     /gene="blpA"
                     /locus_tag="VQ879_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3143240.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10094..10348
                     /gene="blpM"
                     /locus_tag="VQ879_001078"
     CDS             10094..10348
                     /gene="blpM"
                     /locus_tag="VQ879_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3143241.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10364..10567
                     /gene="blpN"
                     /locus_tag="VQ879_001079"
     CDS             10364..10567
                     /gene="blpN"
                     /locus_tag="VQ879_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3143242.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10811..10960
                     /gene="blpO"
                     /locus_tag="VQ879_001080"
     CDS             10811..10960
                     /gene="blpO"
                     /locus_tag="VQ879_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3143243.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11064..11183
                     /locus_tag="VQ879_001081"
     CDS             11064..11183
                     /locus_tag="VQ879_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3143244.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11651..12022
                     /locus_tag="VQ879_001082"
     CDS             11651..12022
                     /locus_tag="VQ879_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143245.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12651..13034
                     /locus_tag="VQ879_001083"
     CDS             12651..13034
                     /locus_tag="VQ879_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3143246.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13086..13775
                     /locus_tag="VQ879_001084"
     CDS             13086..13775
                     /locus_tag="VQ879_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143247.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13817..14050
                     /locus_tag="VQ879_001085"
     CDS             13817..14050
                     /locus_tag="VQ879_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143248.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14201..14812
                     /locus_tag="VQ879_001086"
     CDS             14201..14812
                     /locus_tag="VQ879_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143249.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            14973..15767
                     /locus_tag="VQ879_001087"
     CDS             14973..15767
                     /locus_tag="VQ879_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3143250.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15764..16399
                     /gene="trmB"
                     /locus_tag="VQ879_001088"
     CDS             15764..16399
                     /gene="trmB"
                     /locus_tag="VQ879_001088"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3143251.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16525..17004
                     /gene="rimP"
                     /locus_tag="VQ879_001089"
     CDS             16525..17004
                     /gene="rimP"
                     /locus_tag="VQ879_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3143252.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17048..18184
                     /gene="nusA"
                     /locus_tag="VQ879_001090"
     CDS             17048..18184
                     /gene="nusA"
                     /locus_tag="VQ879_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3143253.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18206..18499
                     /locus_tag="VQ879_001091"
     CDS             18206..18499
                     /locus_tag="VQ879_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3143254.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18492..18791
                     /locus_tag="VQ879_001092"
     CDS             18492..18791
                     /locus_tag="VQ879_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3143255.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18808..21600
                     /gene="infB"
                     /locus_tag="VQ879_001093"
     CDS             18808..21600
                     /gene="infB"
                     /locus_tag="VQ879_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3143256.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21851..22201
                     /gene="rbfA"
                     /locus_tag="VQ879_001094"
     CDS             21851..22201
                     /gene="rbfA"
                     /locus_tag="VQ879_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3143257.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            22480..23259
                     /locus_tag="VQ879_001095"
     CDS             22480..23259
                     /locus_tag="VQ879_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143258.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
     gene            23261..23443
                     /locus_tag="VQ879_001096"
     CDS             23261..23443
                     /locus_tag="VQ879_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143259.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            23440..23580
                     /locus_tag="VQ879_001097"
     CDS             23440..23580
                     /locus_tag="VQ879_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143260.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            23893..24126
                     /locus_tag="VQ879_001098"
     CDS             23893..24126
                     /locus_tag="VQ879_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3143261.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            24126..25460
                     /locus_tag="VQ879_001099"
     CDS             24126..25460
                     /locus_tag="VQ879_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3143262.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            25470..25724
                     /locus_tag="VQ879_001100"
     CDS             25470..25724
                     /locus_tag="VQ879_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3143263.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            25820..26215
                     /locus_tag="VQ879_001101"
     CDS             25820..26215
                     /locus_tag="VQ879_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3143264.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            26628..27077
                     /locus_tag="VQ879_001102"
     CDS             26628..27077
                     /locus_tag="VQ879_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3143265.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            27064..27624
                     /locus_tag="VQ879_001103"
     CDS             27064..27624
                     /locus_tag="VQ879_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143266.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            27624..28202
                     /locus_tag="VQ879_001104"
     CDS             27624..28202
                     /locus_tag="VQ879_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3143267.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            28195..30846
                     /locus_tag="VQ879_001105"
     CDS             28195..30846
                     /locus_tag="VQ879_001105"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3143268.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            30916..31671
                     /locus_tag="VQ879_001106"
     CDS             30916..31671
                     /locus_tag="VQ879_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3143269.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            31946..32749
                     /locus_tag="VQ879_001107"
     CDS             31946..32749
                     /locus_tag="VQ879_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3143270.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(32865..>33134)
                     /locus_tag="VQ879_001108"
     CDS             complement(32865..>33134)
                     /locus_tag="VQ879_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143271.1"
                     /translation="QHDSYHRFLESKGIQASMSRKGNSQDNGRMESFFGILKSEMFYG
                     YEKTFKSLNQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT         9829 a         5879 c         7287 g        10139 t
ORIGIN      
        1 cgtcagttct atccacaacc ttaaaacggt gttttgagca gtctgtgcct agctttctag
       61 tttgcttttt gatttttatt gagtatgagt tacctaaatt atgatgcata gttgatggga
      121 tatatataat agattgaaat agaatatgaa caaattgata agaggatttt aaagtaatct
      181 ctaacaatgc tttagaaact atagtgtgct attctaaatt caattcacta taacttgttt
      241 acgttttaaa aaagagccgg ggggctcttt ttacttatct tcagttccct gcatttcttt
      301 tatcacagct agtctagtct ggatatcctt ttccaagacc ttaaacttgt aagtcaagtc
      361 ttcttggtat tccttgataa gttctttttg ctggttaatg atttgcaggc tgttttggat
      421 aatatccaca tcgtccttga tagcttgaac gcggtcagtg gtattcaaga cttcatctgt
      481 gatggtttgg cgattttttg taaccagata acttccggct gcagctcctg caaatagcag
      541 taggttggat aatttcatag caactcctta agcgtttttg atggtttcag cgacttgagc
      601 aagtttgtca aagtctggtt cgtgggcgat aaaatcaatc ttgaggtcat cgtcagcact
      661 gtagcgaggc acaaggtgaa cgtgagtatg aaaaactgtt tgaccagcga cttcttcaca
      721 gttggaaatg atattcatac cagcagcctt agtgactttc atgacttttt gagctacttt
      781 tggtacttgg gcaaagagtt ggctggcgct cgtagcatcc atctccaaaa gattgcgata
      841 gtgttctttt ggcacgacca aggtgtgtcc tagtgttact tgagagatat caagaaaggc
      901 aaggacctgc tcatcttcat atacttttga agcaggaatt tcccctgcga tgattttaca
      961 aaaaatgcaa tctgacataa aatctacctc tactgtactg aattttgata taatatagct
     1021 acattatacc agatttggag aaaatatgtt agaaattaaa aacctgacag gtggctatgt
     1081 tcatgttcct gttttgaaag atgtgtcctt tactgttgaa agtgggcagt tggtcggttt
     1141 gattggtctc aatggtgctg ggaaatcaac gacgatcaat gagattatcg gtctgttggc
     1201 accttatagt ggctccatca atatcaatgg cctgactctg caaggagatg cgactagcta
     1261 ccgcaagcag attggctaca ttcctgagac gcctagtctg tatgaggaat tgaccctcag
     1321 agagcatatc gaaacggttg ctatggctta cggtattgag caaaaagtgg ctttcgaacg
     1381 agtagagccc ttgttaaaaa tgttccgttt ggaacagaaa ttagactggt tccctgttca
     1441 tttttcaaaa gggatgaagc agaaggtcat gattatctgt gcttttgtgg tggatccaag
     1501 tcttttcatc gtggatgagc ctttccttgg tcttgatccg ctggctattt ctgatttgat
     1561 tcagcttttg gaagtggaga agcaaaaggg caagtctatt ctcatgagta cccacgtgct
     1621 ggattcggcg gagaagatgt gtgatgcctt tgtcattctt cacaagggag aggtgcgtgc
     1681 caaaggcaat ctcctgcaac tacgtgaagc ctttgatatg cctgaggcta gtttgaatga
     1741 tatttacttg gctctgacca aagaggagga tctatgaaag acttgttttt aaagagaaag
     1801 caggcctttc gtaaggagtg tcttggttat ctgcgctatg tgctcaatga ccactttgtc
     1861 ttgttcctgc ttgtcctgtt gggctttcta gcctaccagt acagtcaact cttacaacat
     1921 tttcctgaaa atcattggcc tatccttttg tttgtaggaa ttacgtctgt tttactttta
     1981 ctttggggag gaattgccac ctatatggag gctccagaca agctctttct cttagttgga
     2041 gaagaggaaa tcaagctcca tctcaagcgt caaactggca tttccctagt cttttggctc
     2101 tttgtacaga cccttttctt gctgttattt gcgcccttgt ttttagcaat gggttatggc
     2161 ttgccagttt ttctgctcta tgtgctttta ttgggggtag gaaaatattt ccactttcgt
     2221 caaaaggcca gcaaattttt cactgaaact ggactggact gggactatct tatttctcaa
     2281 gaaagcaagc gtaagcaagt cttgcttcgt ttctttgccc tctttacgca ggtcaaggga
     2341 atttcaaaca gtgtcaagcg tcgtgcctat ctggacttta tcttaaaggc tgttcagaag
     2401 gtgcctggga agatttggca aaatctctat ctgcgttctt atctgcgaaa tggcgacctc
     2461 tttgctctca gtcttcgtct tctcttactt tccgtactgg cgcaggtttt tatcgagcaa
     2521 gcttggattg cgacagcagt ggtagttctc tttaactacc tcttgctctt ccagttgctg
     2581 gccctctatc atgcctttga ctaccagtat ttgacccaac tctttccgat ggacaagggg
     2641 caaaaggaaa aaggcttaca ggaggtagtt cgaggattga ccagttttgt tttacttgtg
     2701 gaagtagttg ttgggttgat taccttccaa gaaaaactag cccttctagc cttactagga
     2761 gctggtttgg ttttactagt cttgtatttg ccttatcagg taaaacgtca gatgcaggac
     2821 taacattgct gatacgacac taaaaaagaa gttgagttca gtctgtctca acttcttttt
     2881 tgttactaca ggataatggt tggtccgtag agacttatac tcttcgaaaa tctcttcaaa
     2941 ccacgtcagc gtcgtcttac cgtactcaag tacagcttgc ggctagcttc ctagtttgct
     3001 ctttgattct cattgagtat taacttggtc ttgacttggt caaagtggaa gcggtcatag
     3061 gcccgccaag cggcgcgagt tggagcatct ggatcaagag cgctgagtcc catgagaaga
     3121 ctggaagtct ggtaaaattt ttccaattca atcaagaatc gattatccac tgtttcagcc
     3181 ttggctagaa aaccaagaat agagtttaat tgctcctgaa agcggacgtc gtcagcggtt
     3241 gcctgtttgc atgcttgata ggctttgttt aagtcagtaa tcaaagtctg agctcttttg
     3301 atagggtctg tatctgtcat gagaattcct cctctaatct gggtgccagt cttgattcta
     3361 gcaactgtgt tttgatactg tcagtctatc acttttatct cctttttcgc ctttaaatct
     3421 ttaattgtca ttgaaatgtc ttgaattgcg ctgagtgaat tttatgataa aatagtggta
     3481 agctcatcat gatattgtag aaaaataatt cttttaggag ctttcaaaga ctgtttagga
     3541 ttgggtgtgc ttgtgttaga ttttttctgt tattcttttc ttaggaggag aatccaatga
     3601 aacatatgat tattcagaca cagaaaacag tctataaagt aaacgtcgac gatgtctact
     3661 atatccaaac acatccaact aaagcccata ctgtaaagat tgttacagaa gaggctagtt
     3721 ttaatatggt tcaaaattta agtaatcttg agaaccaata tggggaaacc ttgatgagat
     3781 gtcatcgaaa ttgtttggtc aatcttgata aagtaaaatc gattgatttt caagaaagaa
     3841 tcctttttct tggagaagaa ggtcaatacg ctgtcaagta tgccagacgt cgctatagag
     3901 aaattcgtca aaaatggttg aaagaaggag agtaagaaga tgagaatatt tgttttagaa
     3961 gatgattttt cccaacagac tagaattgaa acgacgattg agaaactctt gaaggaacat
     4021 catatcactc tgagttcttt tgaagttttt ggtaagccag atcaattgct ggcagaggtg
     4081 catgagaagg gggcccatca gctattcttt ttggatattg agattcgaaa tgaggagatg
     4141 aagggtctgg aagtggctag aaagattcgg gatcgggatc cgtatgccct gattgtcttt
     4201 gtgacgactc actcggagtt tatgcccctg tcctttcgct accaagtgtc tgctctggat
     4261 tatattgata aggccctttc ggcagaggag tttgaatctc gtatcgagac agccctcctc
     4321 tatgccaatg gtcaagacag taaaagtcta gcggaagatt gcttttactt taaatcaaaa
     4381 tttgctcaat tccagtatcc ttttaaagag gtttactatc tcgaaacgtc cacaagaccc
     4441 catcgtgtta ttctctatac caagacagac aggctggaat ttacagcgag tctagaggag
     4501 gttctcaagc aggagcctcg tctcttgcag tgccatcgct cttttctcat caatcctgcc
     4561 aatgtggtgc atttagataa gaaagaaaaa ctgcttttct ttcccaatgg tggaagttgt
     4621 ctaatcgcgc gttataaggt cagggaagtg tctgaggcta ttaataactt acactgagct
     4681 aggagagttt atgaatgttg cttggatatt gttgtataca cttgttactc acggattaaa
     4741 aattgtcata ttctttaagg tagatggaat tagtctcact tttgagagga tttttaaggc
     4801 ctttcttttt aagatactgt tggccgttgt ttttggaatg cttggctata tggtaggaaa
     4861 tgtttaccta tcttatttta tggaaccctt gtacggcata ggcttatctt tcttattgtt
     4921 aagagaactt cctaaaaaac tccttctctt ttatggtctc tttccaatga tattagtgaa
     4981 tctcttttat agaggtgttt cctattttgt gcttccattt ttgggacaag ggcaagtata
     5041 tgatgactac tcatttattt ggttatgtat aataattttc aatttcttca tttctctagc
     5101 ttttttgaaa tggttggact atgatttcac tagcttgaga aaggggattc tcgataaaga
     5161 ttttcaaaag tccctgactc agattaactg gataatgggg gcttactatt tggtgataca
     5221 aaatctgtct tactttgaat atgaacaggg gattcaatca acgactgttc gccatctcat
     5281 cctagtcttt tacctgctct tttttatggg gattatcaag aaattggata cctatttgaa
     5341 ggacaaactc catgagagac tgaaccaaga gcaggacttg cgctacagag agatggagcg
     5401 gtatagtcgg catatagagg agctttataa ggaagtacgg agttttcgcc atgactacac
     5461 caacctcttg actagcttac gtctgggcat tgaagaggag gatatggagc agataaaaga
     5521 gatctacgac tcggtcttaa aggattctag tgaaaaattg caggacaata aatatgacct
     5581 tggccgattg gtgaatgttc gggatcgtgc cctcaaaagt ctcctagctg gaaaatttat
     5641 aaaagctaga gataagaaca ttgtctttaa tgtcgaagtt ccagaggaga ttcaggtaga
     5701 gggggtgagt ctacttgatt ttctaaccgt tgtgtctatc ctttgtgaca acgctattga
     5761 agctagtgta gaagcctgtc aacctcatgt ttcaattgcc ttttttaaaa atggagcaca
     5821 ggagaccttt atcattgaaa attccatcaa agaagaggga atcgatattt ctgaaatctt
     5881 ctcctttgga gcaagttcta aaggggagga gagaggagtt ggtctctata ccgttatgaa
     5941 aattgtggaa agtcatccca ataccagtct caataccacc tgccaagatc acgtttttcg
     6001 tcaggtactt actgtaatac atatagaatg aagaaaaaat aagaccgaga gtgcgttctc
     6061 ttggtcttgt ttttttatag ttgtattggc tgataaaatc cttttgtatt tttttgttca
     6121 attatattaa atctatataa gaaatcttcc caccatcctc cacctataat ttggttgagt
     6181 tcggtagttg ttagttcttg aaatgaagtt aggttttgtt tcttatccat gttatgattc
     6241 tcctttttga taagataata aatagttata gagtgttatc tgaaaattaa tcagaatggg
     6301 ttaaaatttt atctttgaaa taatcaaaat atgttttctt tgtagttaca ctagtgacgc
     6361 gaccttgtaa gccatattgg atgagtttac tatcctcgtt agatagtttt gcaagagcgg
     6421 ttaatttaaa gagattgcct tgctctgttc tggtaggagt ttgatcaata ctctgaagtt
     6481 ggccgatgat ggtggtgccg tgatttccaa tcttctccag ttttaatctt acagtttgtc
     6541 ctttatctag taaggggaga tagtcagatg atacgtagta agtgattagt acttctcttg
     6601 tatctgtgat gacagggaat atttgagcaa tttctgtacc agttggaatt ctatttttac
     6661 cttcaaattc gctgttcaga tgaacgatac ctttacttgg agcggttaag gtattatttt
     6721 ctaagcgctg tgtcgcttga tctagttgta cttttaattc tgttaattga ttctccacgg
     6781 ttagttgttg ctgtgaggct gtttgtaaaa actgagtgcg gagtacttca attttggttg
     6841 ctaaactatt atcataagtt gctacacttc cgataccagc ttgctgaatt ttgatgcttg
     6901 cgatagatga ttcaagactt gcaatacttt gattaatttg agataaaaat ggctcctctg
     6961 ccgttccttg tgtttgtcct tgagaggcta taagataacg atttaaaatt gactggtgcg
     7021 gattgccagt tggtaagcgt gctctgttat ttatgatagc atctctcaac tcttgatatt
     7081 ctccaatttg ttgttgaact tttgtaattt cttgttcgat ggctgatgaa ctgctattgg
     7141 taagattagc ttgatttgaa acttcagtgt tagtctttga gatacccagt tcaatatcat
     7201 gggattgttt agtaaaattc ataaaggtat tatggtagcc aaactcatcc tcgctagaaa
     7261 aaagatcagt cgctttttct aagctttgtt tcaagattcc aagtccttct ttttgcttct
     7321 caagtctttg taattgagtt gctaaggcag ttttctgact ttcttccatt gtttcagagt
     7381 atttgatgag taagtcacct ttctcaacta cttgatttgc cactaaatga ttagcaagga
     7441 taggattatc actggtcgac tgaatagatg caatgacact tgtaggggcg atttctcctt
     7501 gggaagtaac agtaatttct tttgtggcaa caagggagaa aatcaagatg aaagtaaata
     7561 gtaatgaaag aggtataatg aacactgtcg catagttatg gtaacgtctc tgataaaact
     7621 cgacacttct aaaaagatta ggattcatga cattctcctt atttattgaa tagatgatgg
     7681 tagaagcctt gcgcctgcat taactcttgg tgactaccaa cttcaatgat tttcccctgg
     7741 tcaagaacaa tgacacggtt agttcgttcg gctatactga gacgatgggc tacaaagaga
     7801 atggttttat cagttaggga tataagatta tctataacct ttttctcagt caagacatca
     7861 agaccgctag tagcttcatc tagtattaaa acaggagctt tagttaaaag agcacgagcg
     7921 agagcgattc gttgcttttg tcctcctgat agaccagctc catcagagag ctgagtttga
     7981 tagcccatag gcattctttc aatgtcttga cggatttcag ctaattcaca agctcttaga
     8041 atatcttctt ggctaatcat atgattaccg cccaaggtta aattttccaa gatagagcca
     8101 ttaaagatat aggcttgttg gggtaggtaa ttaatatgac ggcgcaagac ttttttatca
     8161 atgtttttaa tatcctgata attgatggaa atatgccctt tgtagggttc aaagaaattg
     8221 acaatcattt tggctaaagt tgttttacca gaaccactaa ctccaactag gctaacctta
     8281 tctccttgtt taatcgtgag attaatatct gttaaggtat ctcgtccaaa accatactta
     8341 taagaaaggt catcaaattc aatatcgccc atcaaaaaat gtgaatgaac agggttttct
     8401 tgaacttgaa attcagattc gactagatag acttcgttca aacggttatt agcgaccttc
     8461 gcagattgga gtttggtttg gaggttgata atattttcca taggagttgt aaagtaagaa
     8521 aaaagtgtgt taaaggtaat cagctgaccg atagaaattt tactcgacat gactaattga
     8581 gcgccaaacc ataggataag gatattcaga actaattttg ttccctgctt taaactcgtt
     8641 tgtaaaatag aatatttact gagcttaaag gatttttcca aataatctac aaattcgctg
     8701 tctatatttt gatagcgatt ttcttcactc gtgagcgact ttatagtttc aatcccgttg
     8761 atatcttcga taatggcaga gctaaccata gaattacttt gcatgacatc atggttcatt
     8821 ttttcgaaag gtttcataaa agaaaagatg atgaacatgt atataggaat ggaaagaaga
     8881 gaaaggagga agagattagg gttttgtgcc agtaagacgc cccctacaag aatcagaata
     8941 gaaacatcca gaaaaagaga aagaatggta gaagccaagg catctataat agagttagca
     9001 tctgtgaacc gtgaaatgat ttctcctgta cgacgtgtcg caaagaaaga catgggaagt
     9061 tcaaaaatat ggcgaatata ggataaaatc acatcaatgc ttaatctctg gctcagaacg
     9121 gttaggagat aatctctgga aaagctcatg acttgttgga ggatataggt gataaccaga
     9181 ccaactgaga tgattcctaa agttgatttc atctgatttg ggatgtattc atccaagatt
     9241 ccttggagat aataagaacc accgatattg ataatagtga ccaataagct tgagagaaca
     9301 atgtaagcaa tgagagattt ttgtttgaaa atcagaggaa ggaagcttag tagaccattc
     9361 tttttatctt tatggggttg atagctgggt ttgggagcta gaaaaatagc tactccagtc
     9421 cattcagaga aaaagcgttc ttttgacatt ttagtgattt ttacagaagg gtcaggatca
     9481 ccaataatca gatagtcttt ctttgtttga tagacaacat agtaatgttg gagttttcct
     9541 tctttgttaa cgtgaacgat aaatggatag gggacatcac tcatgtcaaa gagagtttta
     9601 tctgcttgaa caggccttgt ttcaaagccc atttcatcag cggcttttac aatgccaaga
     9661 gcagtcgtcc cttctttatt ggtctttgca agttctctca agtgagctag agaaaaatct
     9721 gaaccataga atttagcaat cgaggctaag gcagcaacac cgcagtctct agcatctatt
     9781 tgaggaacaa atgtacgttt ataagaagtc attggcaatt cctttcatat agtggatagc
     9841 tctattatga cataaaaaca atttcgtgct ttataaaatc ttgaatagtc attgaaattt
     9901 cctgaatggt aaaaaagtga ttagaaatta tcttttaaaa aaaatttaga ggtagtttta
     9961 aataaaaaag ctaatttaag acgtttcgat gacaattcaa gatttggatg aaaaacttta
    10021 acaaatagtg ctatactaaa cttgtcaaag ttgcaacaag acaaaaatta aaaataaaaa
    10081 aggagtattt gttatgaata caaaaatgat ggaacaattt catgaaatgg atatagctat
    10141 gttatctagt attgaaggag gcaagaataa ttggcaaact aatgttttcg aaggtggtag
    10201 tgctgctttt ggtggctggg ggttagggac agctatttgt gctgcgagtg gtgttggagc
    10261 gccatttatg ggagcatgtg gatacatagg agctaaattt ggtgtggctc tttgggcagg
    10321 agtaacaggg gcaacgggtg gattttaaca aaaggagact tgtatgaata cttattgtaa
    10381 tataaatgaa acaatgctga gtgaggttta cggaggtaat tccggaggag cagctgtagt
    10441 tgctgcttta ggttgtgcag cgggtggagt gaaatatggg aaaattctag gaccatgggg
    10501 cgctgcaata ggaggaattg gaggagcagt ggtttgtgga tatttagcct ataccgctac
    10561 atcataaaaa tgaaagctaa attttatgaa ggctatattc tttattattc tcttcgcttt
    10621 tcaaacctat cttatttatc tatccataag tatctctgat aaaaaacaaa agactattga
    10681 attaacatca ttgaattgtt ttgtcatatt atttctaatc tatgataaat taatttttct
    10741 ctttattgcc tatgtttttt tgataatttt tatattaaac ttgttccgta actgaaaagt
    10801 gacatactat atgaatacaa aaatgatgtc acaattttct gttatggata atgaaatgct
    10861 tgcttgcgtt gaaggtggag atattgattg gggaagaaaa attagttgtg cagcaggggt
    10921 tgcatatggc gcaattgatg ggtgtgcaac aacggtttga catttctatt gggaccattt
    10981 gctataggaa taggtgtaac tggtgctgca ggtggagcta tacttggagg tgtagcctat
    11041 gcagcaacat gttggtggta attatggatt ttaaaagttt tattattggt ttagtagttg
    11101 gtatatttgg tccttatatg gatgacttaa ttagaaaaat attttcaaaa tcttccaaaa
    11161 aggatacgga tagtactctc taaaaaataa atttctcccc tgtatttgct agcttaattt
    11221 acaggggagt ttctttaata ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa
    11281 aagtctacaa acaagttggt atcaatacaa tataaagagg aaagtatgtt tttcatgctt
    11341 gcttttttaa tttttacaat tcaagaggtt ttgatgacca tttatgattt gagtgatcca
    11401 aggtcaaaat aagtgctata ctagcagtgt aaatgttctt gctcaactaa gataaatcgc
    11461 acatttagga ggaaatctta tgaagaaaaa aatactgatt attttcgttc tgtatctgat
    11521 catgtccatc tttctttatc cgcttaggga gagtatttgg tataatctat tttataccat
    11581 agcctatatg attgcggtta tgatctattt ttctttaatt aaaaagaaag aaaagaaatg
    11641 aaagattttc ttgattaaaa agaatcatat tctttgtgag attgttcctg ggtcagttgc
    11701 ctttgcttgt ttctacttat ctatttctat ttcgtcagtt ttccaatttc ttttagtggt
    11761 tattaactta gcttctattt tggtcactgt ttacctcact agggaaatgc ggataaaaga
    11821 gtttgaagat gatgatttgg ttagtcctag aaccaatcaa cttatgttca tcggcttgac
    11881 aggctttatg tctattattt gtttgtatag agggatcaca gcaggagaat cctaccaaca
    11941 aataatcgct tatattggcg ctattctctg cttgaccatc atgcttctgc tcatttgggg
    12001 attgaagtat tataaaaagt agaggctaat gcagtttttg caatttaaga tgtcttgatg
    12061 acaattcaag atttggatga aaaactttga caaatagtgc tatactgaaa ttgtcaaagt
    12121 tgcaacgggt gctgctacat tatgttaaaa atcgctcttg attgataagt tggatttgtt
    12181 aggaaaggag taaataatta tggataagaa aaagatagtt tcgactataa tatgtatagt
    12241 atttcttgta gtgtcagtag ataatttttt tagagactta accccgttac tgttcatttt
    12301 aaatattatt ggcctgtctt gcttttcagt gctaacatac attaacataa aagagatact
    12361 cttaaatata agtaaatgat gatttggtta gtcctagaac caatcaactt atgtttatcg
    12421 gcttggcaga ttttatgttt gtcatttgtt tgtatagagg tatttcagaa acagaattct
    12481 atcaacaact aatcgcttat ataggtgtat tctctgcttg tttatcacgc ttctgctcat
    12541 gtggggcttg aagtattata aaaagtagct ttctatcctt ttctgacagg atatttgagt
    12601 agaaggctct attaaattgt tagtgaaata aatgaatgga ggtatttaat atgaaataca
    12661 gattattttt tgttattttc ttgagtagtg tgttggatat tcttttaggg acatttttac
    12721 aaatctctat cgtatctatt gggtggcttg ttctttacag tggtttgttt gaagcaggag
    12781 ttttccttct tgctaataaa ggggtggcgg taaaaatcaa ggaagtagat attcgaaatc
    12841 gctttaaatt tatttttgga aaaaccttat ggtttcaaat tcttttgctc atctttttga
    12901 taatcaaact ttatcttggt ttggatgcga ggttgatttt attctatgga catattttca
    12961 ttgtctttaa tgccttaatg tatctattat ctagtagtca ggttagcctt aaaaaaaaca
    13021 aactgtcttc ttaatcttac agcagtagag cctgacaagg tgaggtcata gtagggagga
    13081 tttctatgaa aaagtatcaa cttctattca aaataagtgc agttttctct tacttatttt
    13141 tcgtatttgg tctttctcag atgacgctta ttattcaaaa ttattggcaa ttttcttccc
    13201 agattggcaa tttcgtctgg attcaaaatt tcttgagttt gctatttagc ggagtcatga
    13261 tttggattct ggttaagaca ggtcatggtt atctctttca cattccaaga aaaaaatggc
    13321 tttggtattc gattttgaca gtattagtgg tagtgctcca gatctctttt aacgttcaga
    13381 cagctaaaca tgttcagtca actgctgaag gttgggctgt attgatcggt tatagtggga
    13441 ccaactttgc tgagctaggt atctatataa ctttgttctt tctgactcca cttatggaag
    13501 agctaatcta tagaggatta ctgcaacacg ccttttttaa gcattcgaga tttggccttg
    13561 atttgcttct tccgtcaatt ttatttgctc ttcctcattt ttcaagcctg cctagtttgt
    13621 tagatatctt catctttgca acatctggca tcatctttgc tagtttgacc cgctatacca
    13681 agagcattta tccttcctat gcggtgcatg tgatcaataa tattttcgca acattaccat
    13741 ttttgctgac ttttttacat agggtcttgg ggtaaaaaaa caaaaggctt gcttttcagc
    13801 catagaggag attatcatgt ataaacactt atttttccta gattccaaaa ctttagatcg
    13861 gttgacaccc tatattctag tcttggcttc tgacaccatt gcttttaatg tttttgtgct
    13921 aacctttgta tctgcggtgg tttttaattt cctaaattcc atgctagctt taatggctat
    13981 attcataggg gctggctatg tggtcggatt ttggttacta atactcaatg aaaatcaaag
    14041 agcaaactag gaaactagcc gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg
    14101 tttgaatttg attttcgaag agtataaaat ggtttgtttt ggaaaggcta gaactaaaga
    14161 atgacgcgta ggaagtctgt ttggtgagga ggatagtttt atggagtttt ttgataaatt
    14221 tcatgccttg tgttttggat ttttagtact aataattgtc attacagttc cttatacgat
    14281 taaccatggg gttttttttc aaaatgaatc tgcattgatt cttgtaagtc ttcttgtaac
    14341 ctcgctgagt gttgcttatg ctagaaagtt tgaaatgatt tcttttggga tgttaagcaa
    14401 gaaacaactt ttgcttttca ttgcaatctt tcttctaagt gtacttgaga cgctggttta
    14461 tattcatttc ttcgctgttt cttctggctc aggggtccaa cacttggcgg aagtcagcag
    14521 aggaatttcc ctgtctttga ttttgactac ctcagttttt ggccccatcc aggaggaact
    14581 cattttcaga ggacttcttc aaggtgcggt ttttgacaat tcttggttag ggcttgtgct
    14641 aacttcctct ctcttttctt tcatgcatgg accttctaat gtcccttcgt ttatttttta
    14701 tctacttggg ggtttgttgc tgggctttgc ttataaaaag agtcaaaacc tatgggtttc
    14761 tactctagtc cacatgtttt acaacagttg gccactccta tattatttat aaaaattatg
    14821 aaaaggtaag cagaagatgg tgcttacctt tttcaagcta taatgatacc caagccaatc
    14881 cagaggcttt tctttgagaa tcgggttaga gtggttgacg aataggccaa aaactagtag
    14941 aatagtaagg aaactttata cggaggaaag aaatggattt gggtgataat gagctaacac
    15001 tgactcccat acctgggaaa agtggcaagg cttatatggg tagctatcct gacgggaagc
    15061 gcatctttgt aaaaatgaac acctctccaa tcctacctgg tctagctaga gaacaaattg
    15121 ctccacaatt attatggagt cgtcgtttgg cagatgggcg tgatatgtgt gctcaagaat
    15181 ggttgacagg caagatattg accccctatg atatgaatcg taagcaaatc gtcaatattt
    15241 taacccgtct tcatcgctca cgtccgttga tgacacaatt gagtcgtttg ggctatgcca
    15301 tggaaacacc tgtagattta ctacagtctt ggcaggaaac ggctccagat gctttgcgta
    15361 aaaatcattt tatcagtgaa gtgatggctg atttacgtca gactattcca ggatttagag
    15421 aggaccatgc gaccattgtc catggagatg tacgacatag taattggatt gagacagata
    15481 gtggcttgat ttatttagta gattgggatt cggttcgctt gaccgatcgc atgtttgatg
    15541 tggcccatat gctctgccat tatatttcag aacatcagtg gaaggaatgg ttgacctact
    15601 acggttacaa gtacaatcaa acggtattaa gtaaattgta ttggtatggt caattgtctt
    15661 atttgagtca gatttccaag tattatatga accaagattt agaaaatgtc aatcgggaga
    15721 ttcatggttt gcgtcatttc cgagacaagt atggaaagag aagatgagag ttagaaatcg
    15781 taaaggggca acagaattac tagaggcaaa tccccagtat gtggtcctca atcccttgga
    15841 agccaaggca aaatggcggg acttgtttgg caatgataat cccattcatg tggaagttgg
    15901 aagtggaaag ggtgcctttg tttcaggtat ggccaagcaa aaccctgaca tcaactatat
    15961 cgggattgat attcaaaagt ctgttttgag ctacgctttg gacaaggtgc ttgaagttgg
    16021 agtgcctaac atcaagctct tgtgggtaga tggttctgac ttaactgact actttgaaga
    16081 cggtgagatt gatcgcttgt atctgaactt ttcagatcca tggccgaaaa aacgccatga
    16141 aaagcgtcgt ttgacctaca agaccttctt ggataccttc aaacgtatct tgcctgaaaa
    16201 tggagaaatt catttcaaga cggataaccg tggcttgttt gagtacagtt tagtgagctt
    16261 ttctcaatat ggcatgaaac tcaatggtgt ctggttagat ttgcatgcca gtgattttga
    16321 aggcaatgtc atgacagaat acgagcaaaa attctcaaac aaggggcaag ttatctaccg
    16381 agttgaggca gaattttaag agatagccta aaattaggct gtacaagtgc ttttgcttta
    16441 cataagttgg caaacgtgct atactgatag taagaatatg aaaagtgagg cggggaaata
    16501 tcttcgcctc ttgcttatga ggaggtggac gcaatcgcaa caatcgtaga attagtcaga
    16561 gaagttgtag aacctgtcat agaagctcct tttgaactcg tggatatcga gtatggaaag
    16621 attggcagtg acatgattct cagtattttt gtagataaac ccgaaggaat taccttgaac
    16681 gacacggcag acttgacaga aatgatcagt cctgtcctag acaccatcaa gccagatccc
    16741 ttcccagaac aatatttcct agaaattacc agtccaggtt tggaacgtcc tttgaaaacc
    16801 aaggatgccg tcgctggagc ggttggaaaa tacatccatg tcgggctcta ccaagccatc
    16861 gataagcaaa aggtctttga aggaaccttg ttggccttcg aagaggacga gttgactatg
    16921 gaatatatgg acaagacgcg taagaaaacc gtccaaattc catacagttt agtatcaaaa
    16981 gcacgtttag cagttaaatt atagaaaaag aaaggatagc ttttgaggat tcaaaagtga
    17041 agaaaacatg agtaaagaaa tgctagaggc cttccgcatt ttggaagaag acaagggaat
    17101 caaaaaagaa gatatcatcg acgcagtagt agagtcgctt cgttccgctt atcgcagacg
    17161 ctatggtcag tcagacagcg tagctattga cttcaacgaa aaaacaggtg actttacagt
    17221 ttatactgtc cgtgaagttg ttgatgaagt atttgatagc cgtttggaaa tcagcttgaa
    17281 agatgctctt gccattaatt cagcttatga acttggagac aaaatcaagt ttgaagaagc
    17341 accagctgag tttggtcgtg tagcagccca atctgccaaa caaaccatca tggaaaaaat
    17401 gcgcaagcaa acacgtgcca tcacttacaa tacttacaaa gaacatgagc aagaaatcat
    17461 gtctggtaca gtagaacgct ttgacaaccg ctttatctat gtcaaccttg gtagcatcga
    17521 agcccaattg tcaaaacaag accaaattcc tggagaagtt tttgcttctc atgatcgtat
    17581 cgaagtttat gtttacaagg ttgaagacaa ccctcgtggt gtgaacgtct ttgttagccg
    17641 tagccatcca gaaatgatca aacgtttgat ggagcaagaa attccagaag tttatgatgg
    17701 aactgttgaa atcatgagcg tggctcgtga agcaggtgac cgtacgaagg ttgctgttcg
    17761 tagccacaat ccaaacgtgg atgctatcgg tacaatcgtt ggacgtggtg gtgctaatat
    17821 caagaagatt actagcaaat tccacccagc tcgttacgat gctaaaaatg accgcatggt
    17881 accaatcgaa gaaaatatcg atgttatcga gtgggtagca gatccagctg aatttatcta
    17941 caatgccatc gctcctgctg aggttgacca agttatcttt gatgaaaacg acagcaaacg
    18001 tgccttggtg gttgttccag ataacaagct ttctcttgcc attggtcgtc gtggacaaaa
    18061 cgtgcgcttg gcggctcact tgactggtta ccgtatcgat atcaagtctg ctagcgaatt
    18121 tgaagccatg gaagacgctg cttcagtaga gttggaagta gaaaacgata ctgtagaaga
    18181 ataaaagctg ctagaggagg gaaagatgaa aacaagaaaa atccctttgc gcaagtctgt
    18241 tgtgtctaac gaagtgattg ataagcgtga tttgctccgc attgtcaaga acaaggaagg
    18301 acaagtcttt attgatccta cgggcaaggc caatggccgc ggcgcttata tcaaactaga
    18361 caatgcagaa gccctagagg cgaaaaagaa gaaggtcttt aaccgcagtt ttagcatgga
    18421 agtggaagaa agcttttatg acgagttgat cgcttatgtg gatcacaaag tgaaaagaag
    18481 agagttggga cttgaataag caaaagataa gtaatctctt ggggcttgct cagcgagcag
    18541 ggcgcatcat atcgggtgaa gaattggtgg tcaaggccat tcaagacggc aaggccaagt
    18601 tggtctttct agctcatgat gctggaccca atctgaccaa gaagattcaa gataaaagtc
    18661 attattatca agtagaaatt gtaaccgtgt tttcaacact ggaattaagc atagcagtcg
    18721 ggaaatcgag aaaggttttg gctgtaacag atgctggatt tacaaagaaa atgaggtctc
    18781 ttatggaata gaagaggagg acatgatttg tctaagaaaa gattgtacga aatcgcaaaa
    18841 gaacttggaa aagaaagtaa agaagttgta gcgcgtgcaa aagagttggg cttggatgtg
    18901 aaaagccact catcaagtgt ggaagaagct gtcgctgcaa aaattgctgc cagctttaag
    18961 cctgcagctg ctccgaaagt agaagcaaaa cctgcagcac caaaagtaag tgcagaaaag
    19021 aaagccgaaa aatctgagcc agctaaacca gctgtagcta aggaagaggc aaaaccggct
    19081 gagccagttg ctccgaaaac agaaaaagta gcagcgaaac cgcaaagccg taatttcaag
    19141 gctgagcgtg aagcccgtgc taaagagcag gcagaacgac gcaagcaaaa taagggcaat
    19201 aaccgtgacc aacaacaaaa cggaaaccgt cagaaaaacg acggccgtaa tggtggaaaa
    19261 caaggtcaaa gcaaccgcga caatcgtcgc tttaatgacc aagctaagaa gcagcaaggt
    19321 cagcaaaaac gtagaaatga gcgccgtcag caagaggaca aacgttcaaa tcaagtggct
    19381 ccacgtattg actttaaagc ccgtgcagca gccctaaaag cagagcaaaa tgcagagtac
    19441 gctcgttcaa gtgaggaacg cttcaagcag tatcaggctg ctaaagaagc cttggctcaa
    19501 gctaacaaac gcaaggaacc agaggaaatc tttgaagaag cggctaagtt agctgaacaa
    19561 gcacagcaag ttcaagcagt ggttgaagtc gtccctgaga aaaaagaacc tgcagtggat
    19621 acacgtcgta aaaaacaagc tcgaccagac aaaaatcgtg acgattatga tcatgaagaa
    19681 gatggtccta gaaaacaaca aaagaatcga agtagtcaaa atcaagtgag aaatcaaaag
    19741 aatagtaact ggaataacaa caaaaagaac aaaaaaggca ataacaagaa caaccgtaat
    19801 cagactccaa aacctgttac ggagcgtaaa ttccatgaat tgccaacaga atttgaatat
    19861 acagatggta tgaccgttgc ggaaatcgca aaacgtatca aacgtgaacc agctgaaatc
    19921 gttaagaaac ttttcatgat gggtgtcatg gccacacaaa accaatcctt ggatggggaa
    19981 acaattgaac tcctcatggt ggattacggt atcgaagcca aacaaaaggt tgaagtggat
    20041 aatgctgaca tcgaacgttt ctttgtcgaa gatggttatc tcaatgaaga tgaattggtt
    20101 gagcgtccac cagttgttac tatcatggga cacgttgacc acggtaaaac aacccttttg
    20161 gatactcttc gtaactcacg tgttgcgaca ggtgaagcag gtggtattac tcagcatatc
    20221 ggtgcctacc aaatcgtgga aaatggtaag aagattacct tccttgatac accaggacac
    20281 gcggccttta catcaatgcg tgcgcgtggt gcttctgtta ccgatattac gatcttggtc
    20341 gtagcggcag atgacggggt tatgcctcag actattgaag ccatcaacca ctcaaaagca
    20401 gctaacgttc caatcatcgt agccattaac aagattgata aaccaggtgc taacccagaa
    20461 cgcgttatcg gtgaattggc agagcatggt gtgatgtcaa ccgcttgggg tggagattct
    20521 gaatttgttg aaatctcagc taaattcaac caaaatatcg aagaattgtt ggaaacagtc
    20581 cttcttgtag ctgaaatcca agaactcaag gcagacccaa cagtgcgtgc aatcggtacg
    20641 gttatcgaag cgcgcttgga taaaggaaaa ggtgcggtcg caacccttct tgtacaacaa
    20701 ggtaccttga atgttcaaga cccaatcgtt gtcggaaata ccttcggtcg tgtccgtgct
    20761 atgaccaacg accttggtcg tcgtgttaaa gttgctggac catcaacacc agtctctatc
    20821 acaggtttga acgaagcacc gatggcgggt gaccactttg ccgtttacga ggatgaaaaa
    20881 tctgcgcgtg cagcaggtga agagcgtgcc aaacgtgccc tcatgaaaca acgtcaagct
    20941 acccaacgtg ttagccttga aaacctcttt gataccctta aagctgggga actcaaatct
    21001 gttaatgtta tcatcaaggc tgatgtacaa ggttctgttg aagccctttc tgcctcactt
    21061 caaaagattg acgtggaagg tgtcaaagtg actatcgtcc actcagcggt cggtgctatc
    21121 aacgaatcag acgtgaccct tgccgaagct tcaaatgcct ttatcgttgg tttcaacgta
    21181 cgccctacac cacaagctcg tcaacaagca gaagctgacg atgtggaaat ccgtcttcac
    21241 agcattatct acaaggttat cgaagagatg gaagaagcta tgaaagggat gcttgatcca
    21301 gaatttgaag aaaaagttat tggtgaagcg gttatccgtg aaaccttcaa ggtgtctaaa
    21361 gtgggaacta tcggtggatt tatggttatc aacggtaagg ttgcccgtga ctctaaagtc
    21421 cgtgttatcc gtgatggtgt cgttatctat gatggtgaac tcgcaagctt gaaacactat
    21481 aaagacgacg ttaaggaagt tacaaacggc cgtgaaggtg gattgatgat cgactgctac
    21541 aatgatatta agatggatga tgtgattgag gcgtatgtca tggaagaaat caagagataa
    21601 gattttttgc tcctttctta ggtggtgagg gacgcaagca aaccgatggt ttcattgctt
    21661 atttttgagc ctagggtctc aaaaatcccc tgtgatggga ctgataaatc agttccatca
    21721 ctttcaccac ggcgaaagaa gcagatgact tcaaattgaa cttcgtttca atttaaactg
    21781 aaaatcaaga agtttaaaat agctaggtct gctggcctag cttttggttc aaagtagaga
    21841 aaggaatatc atggcaaatc atttccgtac agatcgtgtg ggcatggaaa tcaagcgtga
    21901 agtcaatgag attttgcaaa agaaagtccg tgatccacgt gtccaaggtg tgaccatcac
    21961 agatgttcag atgctgggtg acttgtctgt tgccaaggtt tattacacca ttttgagtaa
    22021 ccttgcttcg gataaccaaa aagcccaaat cgggcttgaa aaagcaactg gtaccatcaa
    22081 acgtgaactt ggtcgcaatt tgaaattgta caaaatccca gatttgacct tcgtcaaaga
    22141 cgagtccatc gagtatggaa acaagattga cgagatgcta cgcaatctgg ataagaacta
    22201 aagaagaggg gttgcccctc ttttttggtg gaggaaaata ggttgaattt gaaatggaaa
    22261 aatattcttt tataatagtt tgaaactaga atagtacgcc tctacttcta aaatattgtt
    22321 agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tgtttcattt tactataaaa
    22381 aaggggttct gtatttttta atgttatcta attagaaaat gctttttttg taggaaatat
    22441 aatatgataa ggtgcaaaaa agaaataagg agtttgtata tggctgaaca agacttagct
    22501 atgcaagtat tgcaacaagt ggtgaaacta cctgttgtta aggttgatcg ttcgaaattt
    22561 ttagtggata agttttccaa agaattgggt ccacaggaca ttcctacctt attggaacaa
    22621 ggtccaacgt ctctcttatc tcaagaaatc ttagatcgag tggctaatgc ctgtattagg
    22681 gataatgttt tattagcgag tgggacttct gttttggcag gattacctgg agggcttgct
    22741 atggcaatta ccattccagc tgatgtggct caattttatg gtttctctct gaaattggcc
    22801 caagaattag gttatattta tggttatgag gatctttggg cttcacgcga tgagttgagt
    22861 gaagatgctc aaaataccct tttgctttat ctaggcgtca tgttgggggt gaatggaact
    22921 gctgctttgc tacgtgctgg tggtataaca attgccaaac aggtaatgaa aacagtacct
    22981 aataaagctt taacaaagac gctttggtat cctattttga agaaagtctt aagaatattt
    23041 ggtgtgaatc ttaccaaggg agggctggcc aaaggaatgg ggaaatttat tcctatcttg
    23101 ggtggtatca tttcaggtgg tttaaccttt gcaactatga aaccaatggg ggaaagcttg
    23161 cagaaagaat tatccaagct agtcaactat agtgaagttc aatatcaaga agatgttgaa
    23221 acaatccgaa aagaggctga aatcatcaaa ggagagtaat atgaatccta tcaaagcttt
    23281 tgctaaaatt tatggtaatt actttttgac cgtgcaaggt gtaaaagtaa tgaaaacgat
    23341 aaagaaagat gataatgccg ttgtcggtct ggggaaactt tttattgccg acaagttaat
    23401 ggatacggct cggtggctca ttaagccaga ggataaaaaa tgaaattttt ctggggactt
    23461 cttgccatta tttttatcaa accgattatt gggattgtga aattcttttg gatgatcatc
    23521 tcttttgcag tccaattgct gttttacaag atattggatt ggttctttaa acttatctag
    23581 atggtaatcc aagtcgcaga gaactagcag gaactccact gctagttttt tattctcttt
    23641 ccatatggta taatataagc agtaaaatca ttttatactc ttcgaaaatc tcttcaaacc
    23701 acgtcagctt caccttgctg tatatatgtt actgacttcg tcagttctat ccgcaacctc
    23761 aaaacggtgt tttgagctga cttcgtcagt tctatctaca atctcaaagc actgttttga
    23821 gcaacctgcg gctagcttcc tagtttgctc tttgattttc attgagtatt agaacatata
    23881 atggaggtcg tcatggacaa tatcatcgat gtgtcaattc ctgttgcaga agtggtggac
    23941 aagcatccag aagtcttgga aattctagtg gagttgggtt ttaaacccct tgccaatccc
    24001 ttaatgcgca atacagttgg tcgtaaagta tcacttaaac agggttctaa gctagcagga
    24061 actcctatgg acaagattgt acgcacactg gaagcgaatg gctacgaagt gattggatta
    24121 gactaatggc agatgaacgg attcatgtcc tacgggatat tttattagaa ttgcataatg
    24181 gcgcctctcc tgagtcggtt caggagcgtt ttgatgcgac ctttgcgggt gtctcagcca
    24241 ttgagatttc ccttatggag cacgagctga tgaactcgga ttcgggcgtc acttttgaag
    24301 atgttatgga actctgtgat gtccatgcca atctttttaa aaatgctatc aaaggtgtcg
    24361 aagtttcaga tactgagcat ccaggtcacc cagttcgtgt cttcaaagaa gaaaatctgg
    24421 ctctccgtgc ggccttgatt cgcattcgta gattgttaga tacctatgag tctatggaag
    24481 acgaggaaat gctggcggag atgcgtaagg gtttggtgcg tcagatggga cttgtgggtc
    24541 aatttgacat ccattaccaa cgtaaggaag aactcttctt tcctatcatg gagcgctatg
    24601 gacacgattc acctcccaaa gttatgtggg gagtggatga tcagattagg gaactctttc
    24661 aaacagctct aacgacagcc aagtcactac cagaagtgtc aattagcagt gtaaaggaag
    24721 cttttgaagc ttttgcgaca gagtttgaaa gtatgatttt caaggaagag tccatcctgc
    24781 tcatgattct ccttgagtct tttactcagg atgactggct tcagattgcg gaggagagtg
    24841 atgcctatgg ctatgccatc atccgtccgt cagagaaatg ggtgccagaa cgacagatct
    24901 ttattgagga aaagattgca gaggagcctg tacaactaga tacggcagaa ggtcaagttc
    24961 aacaagtcat agatacgcca gaaggccatt ttaccattac ctttacccct aaggaaaagg
    25021 aagctgtgct ggaccgccat agtcaacagg cttttggtaa tggctatctt tcagtcgagc
    25081 aggccaatct catcctcaat catctcccta tggagattac ctttgtcaat aaagaagata
    25141 ttttccagta ttacaatgac aatacgccag ctgatgagat gattttcaaa cggacgccgt
    25201 cccaagtcgg gcgcaatgtc gaactctgtc atccgcctaa gtatttggac aaggtcaagg
    25261 ctatcatgaa gggacttcgt gaggggacca aggacaagta tgaaatgtgg ttcaagtctg
    25321 agtcgcgagg taagtttgtc cacatcacct atgctgcagt acacgatgaa gacggagaat
    25381 tccaaggagt gttggagtat gttcaggata tccagcccta ccgtgagatt gatacggact
    25441 attttcgtgg attagaataa ggagaaaaaa tgagttacga acaagaattt atgaaggaat
    25501 ttgaagcttg ggtcaatacc caaatcatga ttaacgatat ggcgcacaag gaaagtcaaa
    25561 aagtttacga agaagaccag gacgagcgtg ccaaagatgc catgattcgc tacgagagtc
    25621 gcttggatgc ttatcagttc ttgcttggta agtttgaaaa cttcaaagta ggcaagggat
    25681 tccatgattt gccagaaggc ttgtttggtg agcgaaatta ttaaacgaga aagattcttg
    25741 atttttcact aaaatcttga tagaatgttt atgttaaatc cttgtcagag cagggatttt
    25801 ttattgaaag gattttatca tgtcaaagaa actcaatcgt aaaaaacaat tacgaaatgg
    25861 cctccgtcgc gcaggtgcct tttcaagtac tgtgactaag gttgtagatg agacaaaaaa
    25921 agtcgtgaag cgtgcagaac agacagcaag cgcagctggt aaggctgttt ctaaaaaagt
    25981 tgaacaagca gtagaagcta ccaaagagca agctcaaaaa gtagctaatt ctgtagaaga
    26041 ttttgcagca aatttgggtg gacttccact tgatcgtgcc aagactttct atgatgaagg
    26101 aatcaagtct gcttcacatt tcaaaaactg gactgaaaaa gaactccttg acttgaaagg
    26161 aatcggccca gctaccatca agaaattgaa agaaaatggc atcaagttca agtaattttt
    26221 cttgagcctt gcatttccga aaaaatcttg ctacaataga gccattagag gtgttttgaa
    26281 tcccacattt tacagaaagt ggcggcgctg agaagtccac aaatgtgtca aaactggttg
    26341 ctaatggatg aaaaattgaa ataaaagtgt ctttttgctt taaagacgag agttgcgggc
    26401 aactgcccga aattgggtgg taccgcggat aaacacattc gtccctgtca tgtagatggc
    26461 agggcttttc ttttacgtct tagtcaaagg gggttgttat gaagcaatct tttaacacaa
    26521 gtaaactata ttatggtttt cctgttttta ttttaggata tcaagattag aattttggct
    26581 ataacatcac gacctgtagt tcctcttata gtctaggaga ttgggttgtg attggagtcg
    26641 ttgcgagaga gaatgccgca gagcagatca aacagtatca aaaatttact gtgaatattt
    26701 ctgatgaaac ttctatgctt gcgatggagc aggctggttt tatcagtcat caggagaaat
    26761 tggaacgttt gggagtgcat tatgaaattt ctgaacgaac tcagactcct attttagacg
    26821 cctgtccact tgttttagat tgtcgggtag ataggattgt tgaggaagac ggtatttgcc
    26881 acatctttgc caagattctt gagcgacttg ttgccccaga actcctggat gaaaagggac
    26941 attttaaaaa tcaactgttt gccccaacct atttcatggg agatggatat cagcgcgttt
    27001 atcgctatct ggacaagcgt gtagatatga agggcagttt catcaaaaaa gcgaggaaga
    27061 aggatggcaa gaactgagct gccagataaa atcgaaacag aacgtctcgt tttacgagtc
    27121 cgtactgtgg cggatgctga ggatatcttt gactatgcta gtttgccaga ggtcgcctat
    27181 ccagcaggtt ttcctccagt caagaccttg gaagatgaga tttattatct ggagcacatt
    27241 cttccggagc gtaatcaaaa ggaaaatctc ccagcaggct acgggattgt cgtcaaagga
    27301 acggataaga tcgttggctc tatctatttc aaccatcgcc atgaagatga tgtgatggaa
    27361 atcggctata ccttacactc agactattgg gggcgaggtt atgtgccaga agctgcgcgt
    27421 gccttgattg acttagcctt taaagatttg ggtcttcaca agattgaact aacttgcttt
    27481 ggatataacc ttcaaagtca acgagtcgcg gaaaagcttg gctttaccct cgaagctcgc
    27541 ataagagacc gtaaagatgc tcaaggcaac tgctgtgatg atttgagata tgccttgctg
    27601 aagagtgagt ggggggtgat ttgatgcatc ttttcatcat tggtgctcca gcatcaggaa
    27661 aaatgaccat tggtcaagaa ttatctcgac tgacggatgc taccctattt tataaccatc
    27721 aagccattga ttttgcacta gaaatctatc aggactatac agaggaaatg tgggaatttg
    27781 ttcgtggaat cactttttca ttccttggag caagtgcaag aaatcagcga tcagtaattt
    27841 taacagatgt aattgatttt tcaaatcagt atcatctgat atatttaaag caaattcaga
    27901 atttgttgga tgattatcat caagagattc tttttgttga gttggaaaca agtcttgaag
    27961 agtgcatacg tcgaaatcga acggagaatc gattaaagca caaaccctta aaacgacata
    28021 ttgaggtatc tgaaagagaa attttagaga ccgctgaaac acttcaatta aattcccaat
    28081 atcaaccgaa tgagttgcac cactacttta aaataaataa tacgaatttg tctgcagaag
    28141 aagctgctaa gcaaattcaa aataaaataa acaaaataga gaaaggacac acacatgtct
    28201 aaagaacttt catctaaata caatccagcc gaggttgagg ctggtcgtta ccaaaaatgg
    28261 cttgatgctg atgttttcaa gccttcaggc gatcaaaagg ctaagcctta ttcaatcgtt
    28321 attccaccac caaacgttac aggtaaactt caccttggtc acgcttggga tacaactttg
    28381 caagatatta tcatccgtca aaaacgcatg caaggttttg ataccctttg gcttcctggg
    28441 atggaccacg cagggattgc cactcaggct aaggtagagg agcgcttgcg tggtgagggc
    28501 atttcccgct atgaccttgg tcgtgagtct ttcttgacga aagtctggga atggaaagac
    28561 gaatatgcca ctactatcaa ggaacaatgg ggcaagatgg ggctctctgt agactactct
    28621 cgtgagcgtt tcactcttga cgaaggtttg tcaaaagctg ttcgtaaggt ctttgtggac
    28681 ctttacaaga aaggctggat ctaccgtggt gagtttatca tcaactggga cccagcagct
    28741 cgcacagccc tttctgatat tgaggtgatt cacaaggatg tcgaaggtgc cttctaccac
    28801 atgaactaca tgctggaaga tggttcacgc gcccttgaag ttgctacaac tcgtcctgag
    28861 actatgtttg gggacgttgc ggttgcggtt aatccagaag acccgcgcta caaggacttg
    28921 attggtaaaa acgtcatcct tccaatcgct aataaactca tcccaatcgt tggagatgag
    28981 cacgcagatc ctgagtttgg tactggtgtc gtgaaaatca cacctgccca cgatccaaat
    29041 gacttcttgg ttggccaacg tcataacttg ccacaagtca acgtcatgaa cgacgacgga
    29101 actatgaatg agcttgcctt tgaattttca ggcatggatc gttttgaagc tcgtaaggca
    29161 gtcgttgcta agttggaaga aatcggtgcc cttgtcaaaa tcgaaaaacg tgtccattca
    29221 gtcggtcact cagaacggac aggtgtcgta gttgagccac gcttgtctac tcaatggttc
    29281 gtcaagatgg accaattggc taagaacgcc attgccaacc aagacacaga ggacaaggtc
    29341 gaattctacc cacctcgttt caacgatacc ttccttcaat ggatggaaaa tgtccacgac
    29401 tgggttatct ctcgtcagct ttggtggggt caccaaatcc ctgcctggta caatgctgat
    29461 ggtgaaatgt atgtcggcga agaagctcca gaaggtgacg gatggactca ggacgaagac
    29521 gtcttggata cttggttcag ttctgccctc tggccatttt caaccatggg ctggcctgaa
    29581 gttgactcag aagactttaa acgttatttc ccaacttcaa ccttggtaac aggttacgac
    29641 atcatcttct tctgggtgtc tcgtatgatc ttccagtcat tggaattcac aggccgtcaa
    29701 ccattccaaa acgtccttat ccatggtcta attcgtgatg aagaaggacg taagatgtct
    29761 aaatctcttg gaaatggcat tgacccaatg gatgttattg ataaatatgg tacagatagt
    29821 cttcgttggt tcttgtcaaa cggctcagct cctggtcaag acgttcgttt ctcttacgag
    29881 aaaatggatg cttcatggaa ctttattaac aaaatttgga acatttctcg ctatatcctc
    29941 atgaacaatg aaggtttgac gctggatgtg gcgcatgaca atgtcacaaa agttgcaaca
    30001 ggtgaggctg gtaatgtgac ggaccgctgg attctccaca atctcaacga aaccattgca
    30061 aaagttactg aaaactttga taagttcgag tttggtgtgg ctggtcatat cctttacaac
    30121 ttcatttggg aagaatttgc caactggtat gttgaattga ccaaggaagt cctttacagc
    30181 gacaatgaag acgataaggt cattactcga tctgttctcc tttacactct ggacaagatc
    30241 cttcgtctcc ttcacccaat catgccattc gtgacagagg aaatctttgg acaaatctca
    30301 gaaggttcta tcgtgacagc tgcataccca actgttaatc tagcctttga agaccttgcg
    30361 gctcatactg gtgtagaaag tctcaaagac ttgatccgtg ccgttcgtaa tgcgcgtgcg
    30421 gaagtaaacg tagcaccaag caagcctatc accatccttg ttaagacaag cgatagcgac
    30481 ttggaagcct tctttaacag caatgtcaac tatatcaaac gctttacaaa tccagaacac
    30541 ttggaaatcg catcaaccat ccctgcacct gaactggcta tgtcaagcgt cattacagga
    30601 gcagaaatct acctgccatt ggctgacctc ctcaatgtcg aagaagaact ggctcgtctt
    30661 gacaaggaac ttgctaaatg gcaaaaagaa ctggacatgg tcggtaagaa gctctctaac
    30721 gaacgcttcg tagccaacgc caaaccagaa gtcgtccaaa aagaacgcga caaacaagct
    30781 gactaccaag ccaagtatga tgcgaccgta gcacgtattg atgagatgaa gaagttggtg
    30841 aaataaacac agaaacatgg tgtaatgccg tgttttttgg gataatgaaa ttactatcta
    30901 ttgatggaga aagtgatgtc taaacacccg cattatgaat tgttaaattt aattggctac
    30961 ggtcttgcca agtttgccaa gctttttata aaagaatttc aatattctag taagtcggag
    31021 ttttatcgct atgtggtttc tttgggaatt gctgaaacaa ctggagttgt aaaaaataga
    31081 atggatttat ttgatcctta ttttgacaat agtcgaaaag gttggtggca gaaagctgaa
    31141 gtttaccgtt ttcgtaaaga tttaattgat atgatgtttg gaaatgaaga tgttcatagt
    31201 tatgttgaaa ttgttaaaat gttacttgct agtgaaggaa agcaaacagg cattactata
    31261 attgaaaaac caattattcg aactaaattc aaacgtctac aggaaacggg gatggaggca
    31321 gagaattatt ttatccttca ttttgataaa gaagaaaaat ttcaaggtgg acagttaacc
    31381 gatgcatgtc tttatggtga tggatatgat ttccaagtag atattcaaga acattcctac
    31441 cttgccgaag ttaaagggat tcgaaaacct aagggtcgtg tccgtttaac tgcctacgaa
    31501 tttgagaaag ctaaagagtt tcaatcagat tttattttat ctctggtcac caacctagat
    31561 gatattccaa agttagtatt agttgataat cctctaaaac attttgagtt taaaaagaat
    31621 attataaaaa atgaaatcat tgaatataga agcgtagagg atttgtatta gttccccctt
    31681 aacttttcca gttgaaggaa cgagaagtct tgacaggtca acgacttaat gaactggaaa
    31741 tcaacggtat tcgtttgact aagttttaag atggcgaaat cggtattgaa tttatcagta
    31801 gtgctgatta taactctttt attatttaca tgaagtatat atatatcata gaacctattg
    31861 tgaggacttt ttatagttta agccagtttc caaccaattt cgtgatttac tggtaatgaa
    31921 gaaaaacaat tgaaaggata tttctatgca atcaacttac aacattgaca atccaaactt
    31981 gtcttatgaa gcgaagcgtg atttatggcg gataggtttt ggtctgcaga aagttgacaa
    32041 tctagtgcca tcagcgtata tggaatcttt ggctgagaaa cagtcccggg gagaactgac
    32101 ttatgagcag gtttatgagg atgcaacggc ttatcaccat actattgatg caagtacgga
    32161 agaggcagac ttggtttctc tacgtattgt agaactattg tctcgaagag gctttagctt
    32221 tagtcctgcg accttacttg ctattcataa ggagttgttt caagatatat ttgaaccctc
    32281 tattccggtg gggcaatttc gtcagaccaa tatcacaaag aatgaacctg ttttgaatgg
    32341 tgaaagtgtt gtgtactctg attactccat gattcaaatg accttagatt atgattttaa
    32401 tcaggaaaaa caagttgcat atgcgacact aactcaggcg gatgtggtta aacaaatcca
    32461 gcattttatt tcaggaatct ggcagattca tccatttcgc gaaggaaaca ctcggacagt
    32521 aacggtcttt ttgattcagt atcttcgtga gtttggtttt gatattgata atataccatt
    32581 tcagcaacat tccaagtatt ttcgtgatgc cttggtatta gataatgcaa agattttaca
    32641 gcgacgtcct gagtttttaa cagctttttt tgaaaatctc ttgctcggtg gtcaaaatga
    32701 tttgtcttca gaaaaaatgt atctagattt agacctcgat ttttcataat ccaaatactg
    32761 agtaaacatt gaattttagg aaaaaatgaa gtaaacattc ccacaataaa acgcatagta
    32821 tcaagtgtta aaatgtactg accccaaaca gttagacaat taatttatcc gaaggattta
    32881 gttctgtatt gcacagggct aagtcctttt agttttacct taattcgttt gttgttgtaa
    32941 taatcaatat agtctataat ggcttgttcc aattgattaa gtgatttaaa tgttttctca
    33001 tagccataaa acatttcgga ttttaaaatg ccaaagaaag attccatcct accgttgtct
    33061 tggctgttgc ccttacgtga catggatgct tgaattccct tactctctag gaaccgatga
    33121 taagaatcgt gttg
//
LOCUS       DAVBOU010000022        33061 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBOU010000022 DAVBOU010000000
VERSION     DAVBOU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33061
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.022"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ879_001109"
     CDS             complement(339..1319)
                     /locus_tag="VQ879_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3143272.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ879_001110"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ879_001110"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3143273.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ879_001111"
     CDS             complement(3669..4772)
                     /locus_tag="VQ879_001111"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3143274.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ879_001112"
     CDS             complement(4762..5130)
                     /locus_tag="VQ879_001112"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3143275.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ879_001113"
     CDS             complement(5169..6200)
                     /locus_tag="VQ879_001113"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3143276.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ879_001114"
     CDS             complement(6202..7233)
                     /locus_tag="VQ879_001114"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3143277.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ879_001115"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ879_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3143278.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10262)
                     /locus_tag="VQ879_001116"
                     /pseudo
     CDS             complement(9973..10262)
                     /locus_tag="VQ879_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10290..10922)
                     /locus_tag="VQ879_001117"
     CDS             complement(10290..10922)
                     /locus_tag="VQ879_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3143279.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10926..11567)
                     /locus_tag="VQ879_001118"
     CDS             complement(10926..11567)
                     /locus_tag="VQ879_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143280.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11560..12351)
                     /locus_tag="VQ879_001119"
     CDS             complement(11560..12351)
                     /locus_tag="VQ879_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143281.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12536..12871)
                     /locus_tag="VQ879_001120"
     CDS             complement(12536..12871)
                     /locus_tag="VQ879_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143282.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13011..13346)
                     /locus_tag="VQ879_001121"
     CDS             complement(13011..13346)
                     /locus_tag="VQ879_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143283.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ879_001122"
     CDS             complement(13437..14747)
                     /gene="der"
                     /locus_tag="VQ879_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3143284.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14761..15474)
                     /locus_tag="VQ879_001123"
     CDS             complement(14761..15474)
                     /locus_tag="VQ879_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET3143285.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDVKPRLPLENVVFEEEYQEQSTETIQAYDRVQADYAGGRATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ879_001124"
     CDS             complement(15471..16367)
                     /gene="dnaI"
                     /locus_tag="VQ879_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3143286.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16368..17537)
                     /locus_tag="VQ879_001125"
     CDS             complement(16368..17537)
                     /locus_tag="VQ879_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3143287.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ879_001126"
     CDS             complement(17538..18011)
                     /gene="nrdR"
                     /locus_tag="VQ879_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3143288.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18151..18516
                     /locus_tag="VQ879_001127"
     CDS             18151..18516
                     /locus_tag="VQ879_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3143289.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18521..19216
                     /locus_tag="VQ879_001128"
     CDS             18521..19216
                     /locus_tag="VQ879_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143290.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19233..20000
                     /locus_tag="VQ879_001129"
     CDS             19233..20000
                     /locus_tag="VQ879_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143291.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20353..21552)
                     /locus_tag="VQ879_001130"
     CDS             complement(20353..21552)
                     /locus_tag="VQ879_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143292.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21549..22442)
                     /locus_tag="VQ879_001131"
     CDS             complement(21549..22442)
                     /locus_tag="VQ879_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143293.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22565..22756
                     /locus_tag="VQ879_001132"
     CDS             22565..22756
                     /locus_tag="VQ879_001132"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143294.1"
                     /translation="MKIKEQTRKPAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23149..23337
                     /locus_tag="VQ879_001133"
                     /pseudo
     CDS             23149..23337
                     /locus_tag="VQ879_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23752..24369
                     /locus_tag="VQ879_001134"
     CDS             23752..24369
                     /locus_tag="VQ879_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3143295.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24412..25299)
                     /locus_tag="VQ879_001135"
     CDS             complement(24412..25299)
                     /locus_tag="VQ879_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3143296.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25448..27331)
                     /locus_tag="VQ879_001136"
     CDS             complement(25448..27331)
                     /locus_tag="VQ879_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3143297.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            27707..29161
                     /locus_tag="VQ879_001137"
     CDS             27707..29161
                     /locus_tag="VQ879_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3143298.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29142..30107
                     /locus_tag="VQ879_001138"
     CDS             29142..30107
                     /locus_tag="VQ879_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3143299.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30142..31416)
                     /locus_tag="VQ879_001139"
     CDS             complement(30142..31416)
                     /locus_tag="VQ879_001139"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3143300.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31416..32588)
                     /locus_tag="VQ879_001140"
     CDS             complement(31416..32588)
                     /locus_tag="VQ879_001140"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3143301.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32719..32967)
                     /locus_tag="VQ879_001141"
     CDS             complement(32719..32967)
                     /locus_tag="VQ879_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143302.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9693 a         7422 c         6236 g         9710 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatactttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctgg ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc cccccagaat cggactgccc caaggaagaa agaagaaagc aatccagatc
    10201 aacagaacta aaccaatata gaccttagaa tagcgtgtaa taaatgattt tagatgtgcc
    10261 ataagccatc tcctaggatt gtatatcctt tacatttgta tatgtccatt ttcgacaact
    10321 aatacatctg tacaaaggtc tgaaatatct tccgatatgt gcgacgtcag gataaccaga
    10381 ccattttctt ttttcaggta agataaaatg acctgtttgg ttaacctcac acttttctca
    10441 tccaaagcat tcataggttc atcgagaaag agtatagaag gagaggaaat aaaggcttga
    10501 atcaaggcca ttttttgctt tgttcccaag gataaatgcc ggtattcaac gtcttcaaat
    10561 tcctgtaaat catagtattg aatccaatag gcaattcttt tttccgtaac tttagatgaa
    10621 aaatacctta acagttccaa attttctctc agggataaat gagataaaaa ctcgactttt
    10681 tcaattaaaa ttcctgcatc ctgaatataa tgatttttta tcccgtaaac tttaccatct
    10741 tgaagaactt ttcctttgtc aagcttaata taaccagcaa gtatctttaa aagaaccgtc
    10801 ttgccagatc cattatcacc tttaagtcca taaatttttc ctgattgaaa caccaaattc
    10861 aactgattta aaataggtct tttcccataa attttctgtc catttataat ttcaagtctc
    10921 atcgtttatc ctttcttaaa tttctcttcc aagcgactaa gaatcaacat aactaataag
    10981 cttaagagta ctaaatacac tgttacaata tgatccatca tccattcttg tcccacaaat
    11041 gccaaaaaat agagaaaaaa agaaaaacca gcgcccgcac taatcagtgc tatcagataa
    11101 gacagtagta agtacaacat cattaactga gcaagtaaaa agaaaagtgc gactgttttg
    11161 aaatgaattc ctagcggaag taaaccaaga aaccagacaa acaaatcttg agtaaaaaat
    11221 ttagaaatga caaccaatcg tttccttgta taatcgaaaa aggagcttga ttgatagcga
    11281 atcaagtgat ggtaatggtc tgccaaatca ctttcaagta aaatgacaga gagccatcct
    11341 accatgaaaa gcgaaaggtt taacaagagt ttggggattt ctaaattcgc ttcagaatag
    11401 tcattatagg aaaaaattga aatcaattct ctcttgaaaa agataacagc atcctgcttt
    11461 tgaaccgctg ttgacaatag atagtttatc aaaatcatca tcagaactat acgaagtagt
    11521 aaaacgatct ttctctttag ccaaatattg ttaaaattct taaacattat cttcatattt
    11581 tttaagtacc atataaggga caacataaag gatataagga gtaaagagtt tcatcaaact
    11641 tacatcccca tagctagctt gcatcaaact cgtcatagga accatatagt aaggcaaggc
    11701 actatagagc agcatagaac caagccaaag aaacatcaaa taggtgattg ccgaacgagt
    11761 cacattcccc acataatcaa ctatttgtaa aaaatagatt gcattgatga aaataccgat
    11821 tagtaggaca caagtaaaga acaaatagct ttttatctct ccatctagga gtctttgtaa
    11881 accactccca tcagaaaata gagaattcca ttcaagagga gaaaaagtcc caaagaaata
    11941 ggttataatt gcaattatca gcacagtcac taaatatatc aaacaaggga tacttgcaac
    12001 ttgcaaagtc aactttcttt ttaacccttg atagctcact tctcttccaa tactcaatcg
    12061 taaaacttta tttttcagct caatatattg aaaacctagc aaaacaatga tgattggaat
    12121 aataaatgat tgataaaaac ctagattgaa ctggagaata cgaaaatcta atgctgattt
    12181 taataagtca tttttaattg cttgtccatc gaatttagct agatcgggcg catgaatatc
    12241 aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa gcaagaaaaa gcaaagtaag
    12301 caagacataa acaaatttat gccttgccaa agttaagaga ggaatcttca taagccacct
    12361 cctacaaata gaaagtaata taatactcaa tgaaaatcaa agagcaaact aggaaactag
    12421 ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa gactgacgaa gtcagttaca
    12481 tatataatcc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaatcaat
    12541 gccttccgcc tttagacttc cctagttccc gtctcaagtc aagcattttt ttgaaacaga
    12601 tatagtctaa ccagtcacta gcaaaagcga taagtagtaa taatagccaa ataccccata
    12661 acttgatatc tgtcaaattt ctcaagacga tattgaaaaa cagaactgaa aaaactgtcc
    12721 aagcaaggct aaaaagagca tagagggtga tgtaaatcca gtaaaaatag taaaaaattg
    12781 ggaaaatctt actatctctg tttgcctttt caatccagct gaaaaagtaa aaacagggca
    12841 ataagattat cattttaaac aagtattcca tcacaaacct cctcttttaa attgttttct
    12901 ttagtttcgt tctattaaat gttattacca atataaacct tggaatagcg tgtaataaat
    12961 gattttagag gtaccataag ccacctccta caaatagaaa ccgatataaa tcaatgcctt
    13021 ccacccttag acttccctag ttcctgtctc aagcgaaaca tttctttgaa acaggaataa
    13081 gttaaccaat tcataccaat agctagcaga ataaaaagaa accaaatgcc ccataacttg
    13141 atatctgtca catttctcaa gacggtattg aaaaacagaa ctgaaacaac tgtccaagca
    13201 aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa aataataaaa aattggaaaa
    13261 aacttactat ttctgttggc cttctcaatc cagttatcaa aataaaagta cggtgctaaa
    13321 agtaagaatt taaacaaatg ttccatcacc gacatcaccc tccttctttt gatagcgttt
    13381 tctattattt tattatatca aaaaaatccg gaactgtcat tccagattct acttttttat
    13441 ttgcgttttc ttgcgatgag atgaatcggt gttccctcaa aaacaaaggc cttgcggatt
    13501 tgattttcca agaaacgcag gtaagaaaag tgcatgagtt cttcttcatt gacaaagatg
    13561 acaaaggttg gtggtttggt tgccacttgg gtcgcataga aaatcttgag acgttttcct
    13621 ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga tgacatcgtt caagacagct
    13681 gatggaatac gtgtattttg actttcgctg atttgcttaa tcatctcagg aagtttgtgg
    13741 agacgttgct tagtcaaagc tgatacaaaa ataatcggtg cataaggcag gtattggaac
    13801 tgctcacgga tatcttcttc ccagtttttc atggtatggt tgtctttttc aagcgtatcc
    13861 cacttgttga ctacgataat cattccttta ccagcttcat gggcaaatcc tgcgatacgc
    13921 ttgtcgtact cacgaatgcc ttcttccgca ttgatgacca tcaagaccac atctgaacgg
    13981 tcaatagcac gcatggcacg cataacagag tatttctcag tattttcata aaccttacca
    14041 gacttacgca taccagccgt atcaatcatg gtaaactctt gaccatctgt atctgtaaag
    14101 tgggtatcaa tagcgtcacg agttgttcca gcaacaggac tggcaatgac acggtcttct
    14161 cccaagatag cattaatcaa gcttgatttt ccaacgttag gacgaccaat caagctaaac
    14221 ttaatgacat ctggattttc ttcttcatat tcatttggaa ggttttccac aatcgcatct
    14281 agtacatccc ctgtaccgat accatggaca gatgagatag gcagtggttc acccaaaccg
    14341 agagcataga aatcatagat atcatttctc atctcagggt tatccacctt gttgactgcg
    14401 aggataactg gtttgtgggt cttataaagc ttgcgggcta cgtattcgtc tgcatcggta
    14461 attccttcct taccggacac gacaaagacg ataacatctg cttcttccat ggcaatttct
    14521 gcctggtgct tgatttgttc catgaaagga gcatcgacat catcaattcc tcctgtatca
    14581 atcatgctaa aagaacgatt gagccactca cccgttgcat aaatacggtc acgtgtcact
    14641 ccttcgacat cttctacaat ggagattcgc tcaccagcga tccgattaaa tagggttgat
    14701 ttcccaacat tgggacgtcc tacaatggca atagttggta gggccataat ttctcacttt
    14761 ctacaataat ttcttctgtt caagattttt tctagttgag cttggttcag cttgaccaaa
    14821 ctgttctgct aggcgctgac tccagcttgt ggtcgcacgc cccccagcat agtcagcctg
    14881 cacacggtca taagcttgga ttgtctcagt tgactgttct tggtattctt cctcaaagac
    14941 aacattctct agtggcagtc tcggtttcac atcatgatgt tgatttggca cacccagtgc
    15001 catcccaaag acagaatagg tgtagtcagg taggttaaag agctctgcca cttcttcaga
    15061 cttgtatcga accaaaccga taatcacacc accatagccc aagctttcag ctgccaacaa
    15121 ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc aagagacctt ccacaccttg
    15181 gggttggaag gtgtcggtat gaagtcgggc tcccttttct gctcggttca aatctccgac
    15241 aaagagaagg aaaacagcag actggcgaat ggcttcttga ggtaccaatt catacaaggc
    15301 atctttcttc tcttgacttc gtaccacaat cacagagtag gattggaaat tcttccaaga
    15361 tgatgccatc tgggctgctg tcaaaatctc atttaagtct acttggggaa tttcttgctc
    15421 tttaaacctg cgcactgaag tatgagcctt catcaattta atggtttctg tcatcgacgg
    15481 tttactcctt ctaaacgagt ctcctcagcc aaataacgga tgcgttccat gacccgtctg
    15541 gcttcccagg tttcgtcatt tccatgtttc actttcgcaa aatgcttctc caaatcttca
    15601 aagttgaagt tggatgtgaa aaaggtcggt aaattttcct gcatccgata ttggagaatg
    15661 acctgcagga tttcgtcacg tacccaaacg gttgattgct cggcgccaat atcatctaaa
    15721 atcaggacct cagacagctt aatctcatcc accaaggtct taacattgcc atcactgata
    15781 gcatttttga catcaatgac aaagctagga tagtggagga gagttgatga aacaccacgt
    15841 ttttctgata aatcatgagc taaggccgcc accatgaaac ttttacccac accaaagtct
    15901 ccatataagt aaagaccttt tcgaatagct ggatattgct ccacgaaggc tagtagcttt
    15961 tcaaaaactg gtaagcgccc caaatcatcc aagtcaactt gagccaaact agctttcttg
    16021 agactggctg gtagattgat taacttgaga cggttcttaa tagccgcttc tttttcagcc
    16081 gcgattagct caggagtttc ttcatatgaa acatctgcat agccatgatt cttaaccaaa
    16141 atcggcttgt agcctttggc aatataatcc gtatccccac ggagaaactt gtcacgctcg
    16201 gtgatgtact gattaaactt ggagatactg cgatttaatt cctctggagt caaggattct
    16261 tgctggataa aagccgcaac atcagggtcc ttcatgattt tctggaccaa atcttgataa
    16321 taaaaacggc tgggttgacg tttgagtacg tctccgacac tttccatcta atctcctcct
    16381 ttttctaatc gagctaatag ttcttgcttc ttacgttcta gttccagacg agtttcctcg
    16441 ctggtttcat tcttatattc aggattactc catttaggaa cattggtttt tactggggca
    16501 gtctgattct gtttttgtgt ttttgctttc tgtcctcgct cacggatgcg caagactgcc
    16561 ttttctgccg aatgaatctt ttgataggca tagtcattgg ctaccttcat ggcatatttc
    16621 tcattgatat ttgccgaatc gaccttatta aaggtcaata aaagaatgat attgatgact
    16681 tcgtccagca agcccaagcc agccatctgt tgcaagagtt ctctttctgt ttgggtaatg
    16741 gttcccttgc gtgtttgctt gatttctgcc aagaactgca gggcagtttt acttttggct
    16801 tctttgataa tggttgtttc cttaagacta aagtcagagg aaactggttt ttgagcaatt
    16861 ttttcacgca tgcgtttggt tgaaataacc tgagaaacag ctgttgactt ggccaattga
    16921 taggtttcaa accaagtcca tttcttctcc tcggcaatag caaagaggtt taagacatcg
    16981 gactgctcat ccgcaaaacg aagtccatct cgagccatca gctggcgaaa atgttccaag
    17041 tcaaaatcat tggccacttt cttcttgaga ccaaggtctt cttgactgcc tagttctgcc
    17101 aattctggaa agacttgatt gagtgagaca ggtatttctt caccatcagc actttcaact
    17161 ttcaaatcct ccacagcaga gtcgccaatc tttttctcta agagtctgcg ataaacagga
    17221 tgctccaaga agtcttgact agatagagga gcatggaggg ctagctgata aacatccccc
    17281 ttttgataga gggtcaagag attaaaagca gataagattt tcaatgattt tatcagtcta
    17341 tccatcccaa agttgagatg attgaggata cttgaaaaaa gatattcctt tctaccatta
    17401 tcccaaaaac tgattgtata aagataaagg ctcagtgcct cctgaccgat aatcgggagg
    17461 tagcactgta ccagagatga ggtatcttgc gacacccgat tattctttag ataagaaaaa
    17521 cggtcaattg gcttcattta tctttccttt ttctttttag aggactgggt gatttgttgg
    17581 agcaagctct ctaactcact gacatcctta aaactacgat agacactagc aaaacgtaca
    17641 taggtaatct cgtccaattc agccaactcc tccatgacga gtgaaccaat gtcctcactt
    17701 tgaatttcat tttcatttcg accacggagt ttctgttcga tacgattgac taccatgttg
    17761 atttcatcac ttgacacagg acgtttctgg gctgagcgga taatcccatt aaagatttta
    17821 tctctggaga attgttcccg tgtaccatct tttttaacaa ccactaaggt tctttcttct
    17881 actcgttcgt aggttgtaaa acggtgttgg cattcgtcgc actcacgtct tctacgaatg
    17941 gtgttccctt cttctgcttg gcgactatcg ataacacttg acttggtagc cccacatttt
    18001 ggacaacgca tcctttccct ccttatcgtt ttcttttcat tataccattt tttaagcgat
    18061 tcccaaaaca attcttcttt ttgcttgaca agttttttgt tttgttgtat tatttaatta
    18121 atacaaaagg ataagagaaa ggagactaag atgtcctgga catttgacaa caaaaaaccc
    18181 atctatttac agattatgga gaaaatcaag cttcagattg tttcccatac actggaaccc
    18241 aatcaacaac ttccaaccgt gagggagcta gctagcgagg ctggtgtcaa tcccaatacc
    18301 atccaaagag ccttatcaga ccttgaacga gaaggatttg tctacagcaa gcgaacaact
    18361 ggacgatttg tgactaagga taaggagcta atcgcccagt cacgcaaaca attatcagaa
    18421 gaagaattgg aacacttcgt ttcctccatg acccattttg gctatgaaaa agaagaacta
    18481 ccaggcgtag tcagtgatta tattaaagga gtttaagcct atgtcattac tagtatttga
    18541 aaatgtatcc aaatcatatg gagcaacacc agcccttgaa aatgtttctc ttgacattcc
    18601 agctggaaaa attgtcggcc ttcttgggcc aaacggctca ggaaaaacaa ccctgattaa
    18661 actaattaat ggcctcttac aaccagatca aggacgtgtc ctcatcaacg acatggaccc
    18721 aagcccagca accaaggccg ttgtagctta tttgcctgat acgacctatc tcaatgagca
    18781 aatgaaggtc aaagaagccc taacctactt caagaccttc tataaagatt tcaatcttga
    18841 acgcgcccat catctacttg cagacctggg cattgatgaa aatagtcgtc tcaagaaact
    18901 atcaaaagga aacaaagaaa aggttcaact gattttggtt atgagccgtg atgctcgtct
    18961 ctatgttttg gacgaaccca ttggtggggt ggatccagca gcccgtgctt atatcctcaa
    19021 taccattatc aacaactact caccaacttc taccgttttg atttctaccc acttgatttc
    19081 tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa gacggaaaag tcgtccgtca
    19141 aggaaatgta gatgatattc gctacgagtc aggtgaatcc attgaccaac tcttccgtca
    19201 ggaatttaag gcctaagcaa aggagattat ttatgttttg gaatttagtt cgctacgaat
    19261 ttaaaaatgt taacaagtgg tatttagccc tctacgcagc cgtgctagtc ctttctgccc
    19321 tcatcggaat acagacacaa ggctttaaaa atctacctta ccaagaaagt caggctacta
    19381 tgctactttt tctagctaca gtctttggtg gcttgatgct tacacttggg atttcaacca
    19441 ttttcttgat tattaaacgc ttcaaaggta gtgtctacga ccgacaaggc tatctgactt
    19501 tgaccttgcc agtttctgaa caccatatca tcacagccaa actaatcggt gcctttatct
    19561 ggtcattgat tagcaccgct gtattggctc taagtgctgt tattattctg gctttaacag
    19621 ctccagaatg gattcctctt tcttatgtga ttacatttgt agaaacacat cttcctcaga
    19681 tctttcttac aggtatatcc ttcctactaa atactatttc aggaatcctc tgcatctacc
    19741 tggctatttc cattggacag cttttcaatg aataccgtac agcactcgct gttgcagtct
    19801 acattggtat ccaaatcgtc attggattta ttgaactttt cttcaatctt agttctaatt
    19861 tctatgtcaa ttcactggta ggactcaatg accatttcta tatgggagca ggtatagcca
    19921 ttgttgaaga actcatattc atagctatct tttatctcgg aacctactac atcttgagaa
    19981 ataaggttaa tttgctttaa ataattttta cctagatatg taacatactc atagaacaaa
    20041 agagaccagg caaaaagtct ttacaattag aaaacgcata gtatcaagtg ttaaaaatcc
    20101 ttgatattat gcgttttttg tgagctgact tatttccttt cactatatcg caaaatgaaa
    20161 taagaacgga acgatgggat tttggaattc aaatcaattt ataagaatgt tttagaagta
    20221 atattatcct attccagatt cagttcacta tacaattgag ttttcaagca acctgtttac
    20281 ataatgtgta cataattagg ttcgtgattc cacccttttc acctttaaaa acctcgcttt
    20341 cgcaaggctc ttctatttat aagataaggc acgtttaaag gttttccaaa tccctaaatc
    20401 atccgtttga agaacgagac tagcatacat gcgtccgata aatcctgttg ctaccaccgc
    20461 aaaaatcact gtaatagcaa gtgaaatcca tgcttccgct ccctccgcat agccattaat
    20521 cgttcgaaac ggcataaaga aggtcgaaat aaagggaata taagaaccaa tcttcaagag
    20581 gagattgtca ccagctgcac ctagagctgt cactccaaaa aaaccaccca taatcaaaat
    20641 catcaaaggc gacaaggctt tccctgagtc ttcaggacga gaaaccatag atcctaggaa
    20701 ggctgccaag actacgtaca tgaaaagact gatcaaaata aagagcaagg tattcagtga
    20761 gatagcatct cccaagtgat ccaaaatacc agactgagcc aagaatggca aatctttaaa
    20821 gagcaaaacg gcagccagac cacctacaac atagatccca atatgcgtta aaatcactag
    20881 aaacagagcc atcatccgcg catagaaata gtgacttgcc cttatgctag aaaagacgac
    20941 ttccataatt ttggtgcctt tttcactggc aacttcctga gctgttacac ccgcataggt
    21001 aatcagaatc atataaagaa agaatcctaa ggcacctgct gcaattgttt gaataaactt
    21061 tttattttcc ttggcttcat caatcttttc tgtgaattga attgtctgcg ctaagcgttt
    21121 ttcctgctct tgagacaagg aagcagttga acgattaagc tgattttgca gttcattgag
    21181 tgtacctgta acctcaaatt taattccatt ttcaagcgat gtttcgccat gataaactgc
    21241 ctttagaaca ctatcttctt gatcaatggt caaataacct tttaattttt cttctttaat
    21301 tgcttctttg gcacttgctt cgtctttata gtcgaagtta acaccattta cattcttcag
    21361 tccttctgct acagatggca ctgttgtcac tactgccact ttattatttt tagccataga
    21421 agaaccttgg agatgcccaa ttcctacaga gattcctaaa aagaggaacg gcgaaatcac
    21481 cataaagaag aaactccatg actcgacatg tcgaagatag gtttccttga ttacaaccca
    21541 catatttctc atacttccac tcctgattct agtttaaaga tttcatcgat agttggcgct
    21601 tgttggtcaa atgttgcgat atattgacct tgagtcaaga ttgggaagag ttcccttcca
    21661 gcgctctcat cctccaaaat caatttccaa ctgccttgtt tggtcaagct cacctgtttg
    21721 acatgaggaa gattttccaa ttcttccttg cttcgttcac ttgaaacaaa gagacgcgtt
    21781 ttcccgtatt gattgcggac atcctgaact ggtccgtgca agaccacacg gccatctcga
    21841 atcatcagaa tatcgtcaca aagttcctca acattggtca tgacatggtc agaaaagata
    21901 atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt tgagcaattc tgtattaact
    21961 gggtccaatc cactaaaagg ctcatccaag ataatcaggt ctggttcatg aatcagagta
    22021 ataatgagct gaatcttctg ctgatttcct tttgacagac tcttgatttt atctgtcagc
    22081 tttcctttta cttccaacct cttcatccat tgagggagtt tttctttgac ttctttggca
    22141 tccatgcctt ttagagtcgc caagtagcga acttgttcaa gaactgtcaa tttaggcatg
    22201 agactgcgtt cttcaggcag ataaccaatc cgagcataga tctcctgacg aatatcctga
    22261 ccatccagac cgatttctcc ctgatattct aggaatttta aaatactatg gaaaatcgtt
    22321 gtttttccag caccattttt tccgactagt cccaaaatac gacctggtcg cgcttgaaag
    22381 tcaataccaa acaaaacttg cttggatcca aaacttttct ctagacttct tacttctagc
    22441 atctttcacc tccgaaattt cttgcactca ttatactcct ttttgatagc ctttacaatg
    22501 ttttttgtcc atttttagaa gactattgct gtgtaaaata tggcctggag cacttttata
    22561 ctcaatgaaa atcaaagagc aaactaggaa gccagccgta gactgctcaa agtacagctt
    22621 tgaggttgca gataaaactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag
    22681 aactgacgaa gtcagtaact atatctacgg caaggcgaag ctgacgtggt ttgaagagat
    22741 tttcgaagag tattagtgat aaatccatta tacagcagca aacttaattt ataccttccg
    22801 ctcctcaact gtctattttt aatcctgaat tgttatttga gtaactcctt tttcctcgta
    22861 aagttttctt cctctaaaac ttctggaaaa aggctaatag tttcagacaa catttttata
    22921 agaaacaagt tcatctgtca tttcaagaag gagtaatcct ttatctacta atggacggaa
    22981 cagaattcaa ccgcttgtcc catatgtttt ctaaggatta tatagtaaaa tgaaataaga
    23041 acaggacaaa ttgatcagga cagtcaaatt gatttctaac aatgttttag aagtagatgt
    23101 atactattct agtttcaatc tgctatatct attatgcaca cccctatagg atctaatgaa
    23161 aatcacaaca ggctcattca tagatagtta cctcaggaaa ctaagaaaac gactacaaag
    23221 gaagtcgcat tcatcgaaaa gtggattaac aactatccta aaaaatgctt gaactacaag
    23281 tcccccagag aagacttctg gatgactaac ttgaacttga aatttagcaa taattaattc
    23341 accatctaac tatatttagt aattatttca gaactgatta atattaaaat taactaacaa
    23401 ttcaaaggat tcatactagc cataaattac gtccatcaga gagagactct tactactttt
    23461 agattttagt ctttctagct tcagaataca tctaaacttt agggaaaatg actattcgaa
    23521 agcgcgaatg cctcaaaatt atctcagata agctattcga aacttagaat gcttttaaat
    23581 ttatggaatt gcgattattt gaaacctaga atgcatataa cctttagttg acagacctat
    23641 tctaagtctc gaagggctat ttactttcta ttccttatca aaaaagactc attccccctt
    23701 tctcctccaa aatatggtat agtagaaata tactatctat gaggagttta catgtcacag
    23761 gataaacaaa tgaaagctgt ttctcccctt ttgcagcgag ttatcaatat ctcatcgatt
    23821 gtcggtgggg ttgggagttt gattttctgt atttgggctt atcaggctgg gattttacaa
    23881 tccaaggaaa ccctctctgc ctttatccag caggcaggca tctggggtcc acctctcttt
    23941 atctttttac agattttaca gactgtcgtc cctatcattc caggggcctt gacctcggtg
    24001 gctggggtct ttatctacgg gcacatcatc gggactatct acaactatat cggcatcgtg
    24061 attggctgtg ccattatctt ttatctagtg cgcctatacg gagctgcctt tgtccagtct
    24121 gtcgtcagca agcgcaccta cgacaagtac atcggctggc tagataaggg caatcgtttt
    24181 gaccgcttct ttatttttat gatgatttgg cccattagcc cagctgactt tctctgtatg
    24241 ctggctgccc tgaccaagat gagtttcaag cgctacatga ccatcatcat tctgaccaaa
    24301 ccctttaccc tcgtggttta tacctacggt ctgacctata ttattgactt tttctggcaa
    24361 atgctttgac acgtaaaaaa tccgtttggt ttcccaagcg gattttgtgc tttattttga
    24421 aacttctttt gcaagaacaa agttcccaag tgtggcagaa ccatttcctg cgactgctgg
    24481 cgtcacgata tagtcacgca catctggtac tggtaggtaa ccattaagaa gagatgtaaa
    24541 tttctcacgg acacggtcca gcatatgttg ttgagccatg acccctccac caaagacaat
    24601 cacgtctggg cggaaagtca ctgtcgcatt aaccgcagct tgagcgatat agtaggcttg
    24661 aacatcccaa acagggttgt tgagttcaat agtttcccca cgtacacctg tacgagcttc
    24721 caaacttgga ccagctgcat agccttccag acatccctta tggaaaggac aaacaccctt
    24781 aaactctttt tcaatatcca ttgggtgtct agcaacataa taatgaccca tttcagggtg
    24841 acccacacca ccgataaact caccacgttg gatgacgcct gcaccgatac ctgtaccgat
    24901 tgtgtagtaa accaagtttt cgatacgacc accagcattg ttacgggcaa ccacttcacc
    24961 gtaagcagag ctgtttacgt ctgttgtgaa gtacattggc acgtttaggg cgcgacgaag
    25021 ggcaccaagc aagtccacat ttgcccagtt tggttttgga gtcgtcgtga taaagccata
    25081 agtttttgag tttttgtcaa tatcaatcgg cccaaatgaa ccaactgcaa gaccagcaag
    25141 gttatcgaat tttgagaaga actcaatggt tttatcgatt gtttcgattg gagttgttgt
    25201 tggaaattgt gttttttcta caacgttaaa gttttcatca ccaacagcac agacaaactt
    25261 tgtaccgcca gcttccaagc ttccatataa ttttgtcatg ataaacctct tgtttttatt
    25321 ttctttatta tagcatactt cgaaagtcta aatgtctcta ttttttagat tttcctctgt
    25381 aaatcttact atctaataaa aacgaacaaa catgtcattt gttcgttttc acattagaga
    25441 ggattgatta gattttcact tcgatcacag catccccctt cgcaactgaa cctgttgcga
    25501 ctggagctac tgaagcgtag tcagctgtat ttgtaacgat aaccattgtt gtatcatcaa
    25561 gtccagctgt agcgatttta tttgagtcaa atgttccaag aacatcgcca actttcacct
    25621 tatcaccttg agcaactttt gcttcaaaac cgtcaccgtt catagataca gtgtcaatac
    25681 caacatgaat caaaacttca gcaccatttc ttgttttcaa accaaaagcg tgccctgttg
    25741 gaaaggcaat tgaaacttca gcatcagctg gtgcatagac cacgccttgg cttggtttca
    25801 cagcgatacc ttgtcccata gctccacttg agaagactgg gtcattgaca tcagcaagag
    25861 cgacaacatc accgacgata ggagttacaa gtgtttcatt ttgaagagct gctggcgcaa
    25921 cttcttcttt ttcttcagcc acttcagctt gttttgcagc tgcagttgcg tctacttcat
    25981 cttcgtaacc aaacatgtaa gtaagagcaa aaccaagggc aaatgataca gctaccataa
    26041 gaaggtattg tggaagttgt ccgttaccaa cataaagcat tgtaccaggg atgatggtga
    26101 taccattacc agtaccagca agtccaagga tagaagccaa tccaccaccg attgcaccag
    26161 caatcaatga aaggaagaat ggtttacgga agcgcaagtt caccccgaag atagcaggct
    26221 ctgtaatacc taggaaggca gaaagagcag ccgggaaagc aagtgttttc agttttggat
    26281 tttttgtttt aacaccaacc gcaacagtag cagcaccttg agctgtcata gcagctgtga
    26341 tgatagcgtt gaatgggtta gcatggtcag cagcaagtaa ttgcacttca agcaagttga
    26401 agatgtggtg cacacctgac acgacgatca attggtgaac cccaccaatc aagaaaccac
    26461 caagaccaaa tggcatgcta agaatcgctt ttgtagcaat aaggatgtag ttttcaacaa
    26521 cgtggaaaac tggtccaatg acaaagagtc caaggataga catgaccaaa agtgtcacga
    26581 atggtgttac caagaggtca atgacatctg gaacaacctt gcggacagct ttttcaaatt
    26641 tagctccgac aaccccgatg atgaaggctg gaagaacgga accttgcaaa ccaacaacag
    26701 ggatgaaacc aaaaaagttc atcgctgtta cttcaccacc ttgagcaact gcccaagcgt
    26761 ttggaagtga gccagagaca agcatcatac caagaacgat accaacggca ggatttccac
    26821 caaatacacg gaaggttgac cacacaacca aacctggcaa gatgatgaag gctgtatctg
    26881 tcaagatttg tgtgtaagtt gcaaagtcac ctggaagtgg catttcaaga gcgttgaaaa
    26941 gaccacgcac acccatgaag agacctgtcg ctacgataac tgggatgatt ggaacgaaaa
    27001 catcaccaaa agtacggata gcacgttgga accagttccc ttgtttagca acttctgctt
    27061 tcatgtcatc cttagatgat gttggtaatc caagtacaac aacttcatcg tacattttgt
    27121 taactgtacc tgtaccaaag ataatttggt attgccctga gttaaagaaa gcaccttgaa
    27181 ctttttccaa gttctcaatc acttctttat tgattttctc ttcatctttg accatgacac
    27241 gtagacgagt cgcacagtgg gcaacactat tgacattttc acgtccgccc aaggcatcga
    27301 tgactttttt tgcaatttcc tgattgttca tttgcaaaaa tctccttata taacattttg
    27361 ttcttgtttg aaagcgattt tattcgccct tacgactatt attttatcat gttttaaaaa
    27421 tatgtcaagc gttttgcata aaaatattct atccacttag tgggcaagct ttagattgat
    27481 tgtttttgac tgtttcatca ggaattcctt gaaaaataag tttgaaacct tggttaaaaa
    27541 gtattttatt tcattatctt tcacattttc gtaaaaattt gattgatttc ctgtatttat
    27601 tttatgataa tcgtttgaca gtttttcctc ttttttaaca taaaaggctt gcatttttta
    27661 tcgaaaacag ttactattaa aagtgataag atttttggag gaatgaatgg aatggacaac
    27721 tgagcgtcgt tacagacttt atcaagattg gacgcaagaa gaaattcaac atataaagga
    27781 aaatatggca caatctccat ggcatactca ttaccatgtt gagccaaaaa caggacttct
    27841 caacgaccca aatggctttt cttactttga tggcaagtgg atcctctttt accagaattt
    27901 tccttttggt gcagcccacg gtttgaaatc ttgggcacag ctagaaagtg atgatttggt
    27961 tcactttaaa gaaactggaa tcaaagtttt accagatact ccattagata gccacggtgc
    28021 ctactctggt tctgccatgc aatttggcga taacttattc ctattttata caggaaatgt
    28081 tcgcgatgaa aactggatcc gtcacccata ccagatcggt gctttgatgg acaaggaggg
    28141 taagattaca aagattgaca agatcttgat tgaccagcca gcagactcta ctgaccactt
    28201 ccgcgatcca caaattttta actttaaagg tcaatactat gctgtcgtcg gtggacagga
    28261 cttggagaaa aaaggcttcg tccgtctcta caaggctgtc aataacgact acacaaactg
    28321 gcaagcagtt ggcgaccttg actttgctaa cgaccgtact gcctacatga tggaatgtcc
    28381 taatctgatc tttgtagagg aacagcctgt ccttctctac tgtccacaag gattggataa
    28441 gaaagttcta gactacgata atatctttcc aaatatgtat aagattgggg cttcctttga
    28501 ccctaaaaat gccaaaatgg tagatgtgtc tcaacttcaa aacatggatt acggtttcga
    28561 agcctatgca actcaagcct tcaacgctcc tgatgggcgt gctctagcag ttagctggct
    28621 tggtttgcca gatgtttctt acccatctga ctgttttgat caccaaggaa ccttctcttt
    28681 ggtcaaggaa ctcactatca aagacgacaa gctctaccag tatccagtcg ctgctattaa
    28741 ggaccttcgt gcttctgaag aagccttctc aaaccgttcc caaaccaaga acacttacga
    28801 acttgaactc aacttggaag ctaatagcca gagcgagatt gtcttacttg ctgataaaga
    28861 aggtaaggga ctttcaatca actttgacct tgtaaacggt caagtgacag tggatcgtag
    28921 ccaggctgga gaacagtatg cccaagaatt tgggacaact cgttcttgcc ctatcgagaa
    28981 tcaggctact actgctacaa tcttcatcga taactctgtc tttgaaattt tcatcaataa
    29041 aggagaaaaa gtattttctg gtcgtgtctt cccacatgcg gaccaaaatg gtatcctgat
    29101 caaatctgga aacccaactg gaacttacta tgaattagat tatggtcgca aaactaactg
    29161 atgtcgccaa acttgcaggc gtcagtccta ctaccgtttc tcgggttatc aataaaaaag
    29221 ggtatctatc tgagaaaacc atccaaaaag tcaatgaagc catgagagaa ttaagctata
    29281 aacccaacaa cctggctcgt agtctgcaag gaaaatcagc taagttaatc ggcttgattt
    29341 tccccaatat ttccaatgtt ttctatgcag aattgattga taaattggaa caccaactct
    29401 tcaaaaatgg ttacaagacc atcatctgca acagtgaaca tgattctgag aaggaacgcg
    29461 aatacatcga aatgttggaa gccaatcagg tagacggcat catttctggt agtcacaacc
    29521 taggaatcga agactacaat cgtgtgacag cgccgattat ttcctttgac cgaaacctat
    29581 cgccagacat ccctgttgtc tcctctgaca actatgctgg tggggttctt gctgcccaaa
    29641 ccttggtcaa gacaggtgcc cagtctatca tcatgattac agggaatgac aattccaatt
    29701 cgccaaccgg actgcgccac gctggttttg catccgtact cccaaaagct cctattatca
    29761 atgtttccag tgacttttct cccgtcagaa aagaaatgga aatcaagaat atcttgaccc
    29821 gggaaaaacc agatgccatt tttgcttcgg atgatttgac agctattctg atcattaaaa
    29881 tcgctcaaga attgggcatt tctgtcccaa aagagctcaa ggttatcggc tatgatggga
    29941 cctactttat cgaaaattac taccctcaat tggctactat caagcaacct ttggaagaga
    30001 ttgcttgtct cactattgat cttctcttgc aaaagattga aggcaaggaa gtcgccacaa
    30061 ctggttactt cttaccagtt acactattac caggaaaaag tatttaaaca caagaaaact
    30121 cagaccgatt cgtctgagtt tttatgatct taaattttcg agatagcgct gggctgtctc
    30181 taggttaaag gttttatctg agatgaggcg ctctactagg ggagcaactt cagattcact
    30241 agccccagct aggagagcta gggatttggc ctgtagtttc atgtggcctt gctggatgcc
    30301 cgtacttacc aaggctttga gggctgcaaa attttgggca agaccgatgg acacgataat
    30361 ctgggctaat tctctggcag aaggatttcc tagtagatca tgactgagag ctacacgtgg
    30421 gttgaggccg atagagccac ccttagtcgc tacaggcatg ggcagggtca tctcaccgac
    30481 caattcttct ctttcaaggt ccagcgtcca gcaactaaga ccttgatagc gtccatctcg
    30541 actggcaaag gcatgggccc cagcttcgat ggcacgccag tcattaccag tggcaatcaa
    30601 aatcgcatca ataccattaa aaattccttt attatgagta gcagctcggt aaggatcagc
    30661 ctgcgcaaac tgactagcca acgcaatttt ctccgcaatc tctcgtcctt gatccttttg
    30721 gcggctcaag tagcgaaagg cgatgcgaca gcttgcagtc accagagaat cggtcgcgta
    30781 gttggacagg attcccatga gactctgtcc ctgactgagt tcttctaaga ctggtttcaa
    30841 ggcttccagc atggtgttga gcatattggc acccatggct tcctgggtat cgacatgaat
    30901 ataaacaacg agaaagtctg gttcgccttt tatctgctcg acatgcagat cacgcgcccc
    30961 acctccacgt ttaacgatag aaggataggc ttgattggca agctccaaga gctccgcttt
    31021 cttgctggca atcttctctt gcgctagttt aggattagca acttgataaa gggctacctg
    31081 cccaatcatc tgtcgctgat ggacttgtgc agtaaaacca cctgcacgct tgatgatttt
    31141 gctggcatag ctggccgccg caaccacaga gggttcttct gtcacatagg gaacggtgta
    31201 ttcctgaccg ttgacaagta cctccggaac cagtgaataa ggcagagaaa aagttcccac
    31261 tacattctca ctcagctggt ctgccacagt cacgctcatc tgttcatcct tctccagact
    31321 agcttgtctc tcaggactaa ggagcgcctg agcttttaac agctcgaggc gctcttggta
    31381 tgatttttta gaaaatccat tccaacttat cttcattatt tttcaacctt gctataacgg
    31441 cgttggtggt cgagaatttc aaccaaggca aaatcttgat tttcatagcc agcaaactgg
    31501 gcagagtttg tttcatccaa gtttacttcc tcaaaaaaga ccttttcata gtctgcaacg
    31561 gataagacag ttcgttggtt gagcttgttc aagcggtctt tatccaaata agcttcatat
    31621 ccttcaacca attcaccact gaagaactca gccacagctc cacttccgta actataaagg
    31681 gcgattttat ccccagcttt caagctatct gtattttcca agagagacaa aagtccaagg
    31741 aaaagtgaac ctgtgtagat attccccacc ttttgactgt agagaataga ctggtcaaaa
    31801 tgcttttgta agaggtcttt tttctcttga ggcaggctct tatccatgat ttttttcaag
    31861 ccttttagcg ctaatttagg ataaggcaag tggaaacaaa cagccgcaaa atcatccaaa
    31921 gtaagctggt agcgtttttg atattcaagc caagtcgttt tcaaactatc caagtattgt
    31981 tgggtagaat agacaccatt tacataagga gttgtcgagt aatttggtcg ccagaaatcc
    32041 atgatgtcac gggtctgagc tacattgtca ttattaaagg ccatcatgcg tggattttgt
    32101 gtaatcaaca tagccacact tccggcaccc tgagtgggtt ctcccggagt ttcaataccg
    32161 tatttggcaa tatcacttgc aatgaccaag accttggact ccggagaatt ttccacatgc
    32221 aatttggcat aatggagggc agcagtcgcc ccatagcagg cttctttaat ctcgaaacta
    32281 cgagcaaagg gctggatgcc cagcaagcca tgcacaaaga cggccgcagc cttactctgg
    32341 tcaattcctg actcggtcgc cacaatgacc atgtcaactt cttgtctttc ttgctcagtt
    32401 aaaatagagt cactagcact ggccgccaag gtcacgatgt cctcagttag gggcgcaata
    32461 ctcaattcct tgagtaagag tcctttactt aatttttcag ggtcaattcc cctcgcttct
    32521 gctaagtctt gtaatttcaa gacatattga ctggtcgcaa aaccaatctt atcaataccg
    32581 attgtcatat ttacctctgt tttatcattc atgtaaaaaa tcgttctata ctattttatc
    32641 acaaatggca gtaaaagaga gaaaaaagac ttgattcacc aaatcaagcc tcttattggt
    32701 catcatttta aagaatgatt agttgctaga gagttcaccg atataagtag ctttataagc
    32761 tccattcaca gttatcagct cctggaggat caaatttcct gagtaagtcc ttcccatctc
    32821 atctacaaat ttttgataaa actgactggt cggaatttct ctgacatcct tatcaaatgt
    32881 cttatcaagt gttttactaa ccttctcagc aatcaattga tgctcttgcc atccactttg
    32941 aaactctgag cccgaactag aaaccatgac tgggataaac aacaaggtca gtagatttac
    33001 agacaataag gaaagtagta gacttcctgc aaaactagaa tcctagttca tgattgataa
    33061 t
//
LOCUS       DAVBOU010000023        31445 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBOU010000023 DAVBOU010000000
VERSION     DAVBOU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.023"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..114
                     /locus_tag="VQ879_001142"
     CDS             <1..114
                     /locus_tag="VQ879_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3143303.1"
                     /translation="IQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            114..875
                     /locus_tag="VQ879_001143"
     CDS             114..875
                     /locus_tag="VQ879_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3143304.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            903..2060
                     /locus_tag="VQ879_001144"
     CDS             903..2060
                     /locus_tag="VQ879_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143305.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            2879..3238
                     /locus_tag="VQ879_001145"
     CDS             2879..3238
                     /locus_tag="VQ879_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143306.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            3314..3612
                     /locus_tag="VQ879_001146"
                     /pseudo
     CDS             3314..3612
                     /locus_tag="VQ879_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            3599..5463
                     /locus_tag="VQ879_001147"
                     /pseudo
     CDS             3599..5463
                     /locus_tag="VQ879_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5508..6360)
                     /locus_tag="VQ879_001148"
                     /pseudo
     CDS             complement(5508..6360)
                     /locus_tag="VQ879_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            6442..6513
                     /locus_tag="VQ879_001149"
     CDS             6442..6513
                     /locus_tag="VQ879_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3143307.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            6617..7486
                     /locus_tag="VQ879_001150"
     CDS             6617..7486
                     /locus_tag="VQ879_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3143308.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            7473..8195
                     /locus_tag="VQ879_001151"
     CDS             7473..8195
                     /locus_tag="VQ879_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3143309.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            8192..8722
                     /locus_tag="VQ879_001152"
     CDS             8192..8722
                     /locus_tag="VQ879_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143310.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            8726..9820
                     /locus_tag="VQ879_001153"
     CDS             8726..9820
                     /locus_tag="VQ879_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143311.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            9823..10494
                     /locus_tag="VQ879_001154"
     CDS             9823..10494
                     /locus_tag="VQ879_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143312.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            10496..11524
                     /gene="galE"
                     /locus_tag="VQ879_001155"
     CDS             10496..11524
                     /gene="galE"
                     /locus_tag="VQ879_001155"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3143313.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            11548..12792
                     /locus_tag="VQ879_001156"
     CDS             11548..12792
                     /locus_tag="VQ879_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3143314.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            12842..13201
                     /locus_tag="VQ879_001157"
     CDS             12842..13201
                     /locus_tag="VQ879_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3143315.1"
                     /translation="MISRIGDIMFDFANNTFLAGLNPTSLSVVAIYQSLESMIGVLFN
                     LFGGVIADSFKRKKIIITTNILCGIACITLSFISQEKWLVYAIVITNVILAFMSAFSG
                     PSYKAFTKEIVKKDSIS"
     gene            13253..14005
                     /locus_tag="VQ879_001158"
     CDS             13253..14005
                     /locus_tag="VQ879_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3143316.1"
                     /translation="MIAIFLYKLLGIHGVLLLDGLSFLIAASLIFFITPVNEEVDTKE
                     NMTIRGIFDDLKIGFTYVYSHKQILTIIALSALVNFFLAAYNLLLPYSNQMFGSISSG
                     LYGTFLTAEAIGGFIGAILSGFINKSLSSKRLMLFLAYSGLMLMLTAPIYYMFRNVII
                     LAFTPALFSLFLSIFNIQFFSIVQRDVDNEFLGRVFGIIFTVAILFMPLGTVFFSVVL
                     NPNNTFNFFIIGVSITILSLIFSTLLKRYDRS"
     gene            14685..14906
                     /locus_tag="VQ879_001159"
     CDS             14685..14906
                     /locus_tag="VQ879_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143317.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15354..15656
                     /locus_tag="VQ879_001160"
                     /pseudo
     CDS             15354..15656
                     /locus_tag="VQ879_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            15812..17041
                     /locus_tag="VQ879_001161"
     CDS             15812..17041
                     /locus_tag="VQ879_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3143318.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            17061..19757
                     /gene="ppc"
                     /locus_tag="VQ879_001162"
     CDS             17061..19757
                     /gene="ppc"
                     /locus_tag="VQ879_001162"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3143319.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNISFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    19840..20057
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20170..21174
                     /locus_tag="VQ879_001163"
     CDS             20170..21174
                     /locus_tag="VQ879_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3143320.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            21243..22109
                     /locus_tag="VQ879_001164"
     CDS             21243..22109
                     /locus_tag="VQ879_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143321.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            22106..22864
                     /locus_tag="VQ879_001165"
     CDS             22106..22864
                     /locus_tag="VQ879_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143322.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            22954..24714
                     /gene="dnaG"
                     /locus_tag="VQ879_001166"
     CDS             22954..24714
                     /gene="dnaG"
                     /locus_tag="VQ879_001166"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3143323.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            24717..25826
                     /gene="rpoD"
                     /locus_tag="VQ879_001167"
     CDS             24717..25826
                     /gene="rpoD"
                     /locus_tag="VQ879_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3143324.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            25840..26169
                     /locus_tag="VQ879_001168"
     CDS             25840..26169
                     /locus_tag="VQ879_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3143325.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            26284..27327
                     /gene="cpoA"
                     /locus_tag="VQ879_001169"
     CDS             26284..27327
                     /gene="cpoA"
                     /locus_tag="VQ879_001169"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3143326.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            27343..28668
                     /locus_tag="VQ879_001170"
     CDS             27343..28668
                     /locus_tag="VQ879_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3143327.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            28699..28875
                     /locus_tag="VQ879_001171"
     CDS             28699..28875
                     /locus_tag="VQ879_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3143328.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            28934..29068
                     /locus_tag="VQ879_001172"
     CDS             28934..29068
                     /locus_tag="VQ879_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3143329.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            29132..30442
                     /gene="obgE"
                     /locus_tag="VQ879_001173"
     CDS             29132..30442
                     /gene="obgE"
                     /locus_tag="VQ879_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3143330.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            30452..30610
                     /locus_tag="VQ879_001174"
     CDS             30452..30610
                     /locus_tag="VQ879_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143331.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT        10504 a         4776 c         6355 g         9810 t
ORIGIN      
        1 attcagacaa atatctattt agtagaaaat tttgatgaaa tagagagata tagcggctat
       61 ttggatggaa ttgaacgtat gttagagata tctgaaaaac ggatggtagc ctagtggaaa
      121 tccaagatta tactgacagt gaattcaaac atgctctagc acggaatctt cgttcactga
      181 caagaggaaa aaagtccagt aagcaaccta tagcgatttt gctcggaggg caaagtggtg
      241 ccggtaagac tacaattcat cgtattaaac agaaagaatt tcaaggaaat attgttatca
      301 tagatggaga tagttttcgt tctcagcatc cacactattt agaactgcag caagaatatg
      361 gcaaagatag tgtagaatac accaaagatt ttgcaggtaa aatggtagag tctttagtaa
      421 cagaattgag tcatttggga tacaatcttt tgatagaggg aactttacga acagttgatg
      481 ttccaaagaa aacagcacaa ctcttgaaaa ataagggata tgaagtacaa ttagccttga
      541 ttgcgacaaa gcctaagctg tcctatctga gcactcttat tcgatacgaa gaactgtacg
      601 ctatcaatcc aaatcaagca cgcgcaacac caaaagaaca tcatgatttc attgtaaatc
      661 atctagttga taatacacga caattggaag aactagctat ttttgaaaga attcaaattt
      721 accaacgaga tagaagttgt gtatatgatt caaaagaaaa tacaacttca gcagcagatg
      781 ttcttcatga gttattgttt ggagagtgga gtcaggtaga aaaggagatg ttgagggtag
      841 gggaaaagag acttaatgaa ttacttgaaa aataaacaat tgatattttt aggagagtag
      901 aaatgagagg gtttaataac aagataaagt ctgtttatca agaactaaca aattccaaag
      961 agaaattcgg tagctttcac aagactttaa ttcatttgca tacacctgtt tcttatgatt
     1021 acaagctatt ttctaattgg actgcaacga aatatagaaa aattactgaa gatgaactat
     1081 atgatatatt ttttgaaaat aagaaaataa aagttgataa gacaattttt tttagtaatt
     1141 ttgataaggt tgttttttct agttcaaaag aatatattag ttttcttatg ttagcagagg
     1201 caatcataaa aaatggaata gaaatagttg tagtaactga tcataatact accaaaggta
     1261 ttaaaaagtt acaaatggca gtctcaatca taatgaaaaa ttatccgatt tatgatatac
     1321 atcctcatat tttacatgga gtagaaatta gtgcagcaga taaattgcat attgtatgta
     1381 tatatgatta tgaacaagaa tcatgggtta atcaatggtt aagtgaaaat attataagta
     1441 agaaagatgg aagttatcaa cattcactga ctataatgaa ggatttcaat aatcaaaaaa
     1501 tagttaacta tattgctcat ttcaatagtt atgacatttt gaaaaaaggt tctcacttat
     1561 caggtgcata taaacgaaaa attttttcta aagaaaatac acgatttttg gagtttaata
     1621 ttaactcgaa agaatcttcg caacaacttg atattctcta taaagaagtt ggtgtattaa
     1681 gtttgggaca aaaagttgta gccatgcttg attttttatt agcatatagt gactattcta
     1741 aagacttcag accattgatt attgatcagc ctgaagacaa tctagacaat cgttatattt
     1801 acaggcattt agttcagcag tttagagatg tgaaagctca acgtcaaatt attttagcaa
     1861 cacataatgc tacaattgta acaaattcta tgacagatca agttgttatt atggagtcag
     1921 atggagttaa cggatggatt gaatcacagg gatatgttag tgaaaaatat ataaaaaatc
     1981 atatcatcaa tcaattagag ggaggaaaag attccttcaa gcataaaatg tctatatatg
     2041 agacggcttt atcagagtag agtcagaaaa agtaggttag aaatttagcc tacttttttc
     2101 tttgttcgac aggcatagtg tacatctgag gtccaagtcc tctgtggata tttgctgcag
     2161 atgaaaccaa tagcgactcc taagcctgaa tatcgtgatg taggggggat aggaaggaat
     2221 tagcgaaatc aaggttctac aaacagaatc gtgacttgaa gccatatata gcggatgagg
     2281 aactctaaaa tccaaatagg tgtcgtaacc tatatacgta aattacgaga gtaaactagg
     2341 aaagatgtac ggcttattcc gtgagcgttt aggacgtagt acaacgaatc atgggagtca
     2401 gctgaacaca tagtattgaa gaaatttctg taatggaaat ggagcgaaga agtgaacaat
     2461 taaatgaata cctctctaat taaatttgtc aattctaatt cctggtatga aaagacagtg
     2521 acctaaaaat gtaaacgatg ggagctgatc ataaatatag gacggtacat gcagtggtgt
     2581 tagagattag tccctacttg atttgtgata acttccccaa ctttcttctg ctatactttt
     2641 ctcaactttt aaaaatccaa ctaagaattt tacctgggag tttgggggcg tagccaccaa
     2701 gttatcttat ggttagctgt caaaactgga aggttttggt tagctggcga tatgattttt
     2761 tgggtattgt gaccacaatg cctgagctcg caaagaccga acaaggactt taagaaattt
     2821 cccgtatgac acacggggtc ggggtttacc cgagaaagga tgaaagtgag gaaaagagat
     2881 gtctgaacag taccgtgaca ttcgaaaaga ggtaaatcta accgcagatg agctaaaaca
     2941 gattgaaaaa atgatggagg ttgataatta tcgtcacttt tcaccattcg tcagggataa
     3001 aattttgatg actgatgaca aacagttagc tgccaaagaa tggttttccc tttggcagtc
     3061 tcaaaagttt gaacagatca gtcgagatgt gcatttggtt ttgattatcg caagagagaa
     3121 tcatcaagtg actcaagagc acgtctcaat cttattgact tgtgttcaag aattaattgt
     3181 agaagtcaat caagctcagc cactcagtcg tgaattctgt gaaaaatata tgggatagga
     3241 gactgctatg gtttatcgtt atcgtactaa tctaaaaaaa tatttctaac tgattcagaa
     3301 ttgaattaat taaatgatcg tattactaag agtcactgtc aaaatttctc agtctacgcc
     3361 agaaaagttt tgcttaatcc caatatgtca tttgtcacga ttaacactga tacttatgaa
     3421 cagttagtgt ttgaattgag gaggattgga aataacatca atcaaattgc gcgtgcgatt
     3481 aatcaaagcc atctgatttc tcaggaccaa ttacaagaat tgagtaaagg agtcggagag
     3541 ttaattaagg aagtggacaa agaatttcaa gtggaggtga aaagactgaa ggagtttcat
     3601 ggtagttact aaatactttg cgacgcacgg aaaaaaatat cgtaggcgtt tgattaaata
     3661 tatcctcaat ccagataaaa cagataatct aaaattagta tctgattttg gcatgagtaa
     3721 ttacttagat tttcctagcc atgcagaaat ggtagaaatg tacaatgtta actttactaa
     3781 taacgacaag ttgtacgagt ccagaaatga ccgacaagaa aaacaccaac aaactattca
     3841 tgcccatcat ctcatccaat cattttctcc tgaagataat ctgacacctg aagaaattaa
     3901 ccgcattggt tatgagacca tgatggaatt gacaggaggt cgttttaagt ttatcgtagc
     3961 aactcacaca gacaaagatc atgttcataa tcacatccta attaacgcta ttgaccgcaa
     4021 ttcagataaa aagttgatat ggaactatgc cttggaacga aacctccgta tgatttcaga
     4081 ccgtatttct aaaatggctg gtgcaaaaat tattgagaaa cgttattcct atcgagatta
     4141 taaaaaatat aaggaatcta gtcataaatt tgaattgaaa caacgtcttt attttttgct
     4201 tcagcaatct aaatcgtttg atgatttttt agagaaagca aagcagttgc atgttcagat
     4261 tgattttagt caaaagcata gccgtttttt gatgacagat agaacgatga taaaaccaat
     4321 tcgaggtcgc caacttagta aacgagattt atatgatgaa gactttttta aaacatattt
     4381 tgccaaacaa gagattgaaa gtcatttaga atttttgttg aaccgtgtca attctttaga
     4441 agagttaata acaaaagcaa aagaattgaa tctaaccatt gacttaaaac aaaaaaatgt
     4501 aacttttatc ctggaagaag ataatcaaaa gataagtttg ggtcataaaa aataagtgat
     4561 aagaaattat atgatgtcaa attttttcaa gattatttta aaaataagga agtcgttgct
     4621 tcagaaggat tagagaattt ataggaacag taccatgctt tccaagaaga acgagataag
     4681 gataaagtat ccactgaaga gattgaggaa gcctttgaga tatttaagga aaagagagat
     4741 gctgttcgtg aatttgaagt ggaacttgca gagaaccaaa tagagaagct agttgatgag
     4801 ggaatttata tcaaagtgtc ttttggtatt aagcagagtg gtcttatttt cattcccaat
     4861 tatcaattgg atactatgga agaagacaat cagaaaaaat ataaagtcta cattcgagaa
     4921 acgtcttctt actttgtcta taataaagaa aacatggata ataattgttt catcaagggt
     4981 aggaccttaa tcagacaatt gagcaacgat agccaaaaac tcccctatag acgaccaact
     5041 ttaaaaagtc ttcaagagaa gatttctaaa attaatctta tgattgaact atctaacacg
     5101 aacaaacaat accaagaaat caaagatgag cttgtattag aaattgcaga gattgatatg
     5161 cagctagaag aaacccaaga aaaaatcgcc accttaaaca agatggcgga agtccttatc
     5221 aatttgaaga gtgaagatca tgagactaga aaattagcta agtatgattt tgaccaaatg
     5281 aacatgacgg aatcaataat gttagatcga ctcaatacgg atattttaaa attacaacag
     5341 gaacttggta atgaaattaa taaatatgag gagatagcta gaagattgga tttgtttgtg
     5401 aaaattatta ataccaataa atttacagtt ctaaaatttc acgagaatgc cttactagaa
     5461 taatattatt tacgactaat tagttaaaag atagagaata atttcattta ttttttattt
     5521 actagtttat taaaatggtc agtatagtgt aattttaact tgtattctcc taaaatatcg
     5581 agaacttgta tagcttgttt cattgtttca ataccactac ttaattgacg tttaaattca
     5641 tagtaaccgg ttgcatagag aaaaactgtc tgttcataaa agtttaattc attctctaac
     5701 aatcccttta tctcattaat taaataagag caattagaaa attcttcttt atctatgctg
     5761 agaatgaaac aatttatagc tagctgagtg acaatccgct tatttgtttt atttagagat
     5821 gagtaaatat aattatttaa catttcttta gttaagtaag aagtaggagt tgtagttaat
     5881 tgttcgtaca cagttaccta ataaaataat ctcataataa ccccattttt caactttaaa
     5941 gagataatct gctagttgaa gtaattcatc atctgatgga atgattcttg aatccattgt
     6001 gtgtaaaatg gattttacca ttgttttttc aaaagaatct aaagtgtaat ttgaggaatc
     6061 cgaaagtaga gattgtatat tattgatgtt ttgtaatgaa tattgtttac ggatatactg
     6121 tattaagttg gcaaatgact cagtttttgt atagtcttca tcgtgtaaaa taagaaactc
     6181 atccaaagta atgtgtaatt tgtctaaaat attgatcagt cggatacatg atatctctga
     6241 ctctccacgt tcaaatcggg atatttgcga ttttgaaaga tgctcatcag caacagagca
     6301 tagactgatt tgtttgcctt tacgaacttt tctaagtgtg atgccaagtt ttgatttcat
     6361 agtttttccc attttcccaa caaaaagtta acttagtttt atttattgta caataaataa
     6421 aaattgaaag gaagtctaaa tatgaagaaa atttcaaaat ttttcccaat tttgatgcta
     6481 gtgatggaca ttatcattat tgttggtggt taaatcactt aggtgtacac ctaagtcttt
     6541 agagtatcta aagactatac ttactagcta aaacatattt aagttaaatc gtaaaatttt
     6601 agagagtggt gagactttga aacataaaaa agtattaatt atagggtatg gtataatgac
     6661 tcggggtata ttaaaaatcc tgaaacagtc gaaaaaatat aatatatacc tatatagtag
     6721 gcatctaaat tcaacaataa atggaataat atttattaga gaagatgaat tacctgatgc
     6781 tataaatcag gttgatttta taatcacttg ttttagtaat catattgaaa cggataattt
     6841 cattaatgag tttttattaa atatacaatc acttcgtaaa accatagtaa ttgattttac
     6901 aacctccagg attgattgcg ttgaaaaatt taaaaaaact gttgaaatta aagggggata
     6961 ctatatagag gctcctttca caggaggtaa gttaggaagt aatagtggtc aactatcaat
     7021 ttttttacat attgatgaag gtgtaaacta taataaaaag gagttaatgg aattattaaa
     7081 attaatttca aaaaaaatat acttttttga aaagagtacg gaaccaacaa aattcaagtt
     7141 aatttataac tcgtggggag cgtatttgct ttactctatt aagctattca accctttaca
     7201 gtatgatttt tcaccaaagt ctctagaggt agcgaataca atcgtatgta atgatggttg
     7261 gatgagttta gtatgcaact ccaaattaga acagatcaat gatcaagatt ttgatgacat
     7321 acactttaga gtagaatata tggtaaaaga tttagaatat gctaattttt cagtctttca
     7381 tgatgaagtg aaagaaataa attatttatt acagcaatat agggattgct tagtaactga
     7441 tagtggaaaa gattatacgg taataggaaa gtatgataac ttataggaat gacttgctgt
     7501 ctaaagaatt agatatacta atttcatttt ttaaaaaatg cgaggtagga aaaatttcac
     7561 tcgttattac tggttccttg gcaagaggta atccaagaat caaggatggg aaattagaat
     7621 cggatattga tattctagtt atagtagaca gtattcagca attaattagt ataaaaaaga
     7681 ctttagaggg aaggtttcac tttgtacata aaatttcttt gattttttgt ttgaaggaaa
     7741 gaataaatcg aagtcgttat cgtggaatta ttaatagtat tagaagtgta gataatcttt
     7801 tagtagataa tctgcatata aaaaatcaaa taatagaagc tttagactca cctaccaata
     7861 ttgtggagca gactcgctct atgattcagg aattttgtta ttattcatca aaatatttaa
     7921 tttcaaagaa taattatttg gaattaaaac tagaaaagta ttggaaggag attgcaacat
     7981 taaatcatat cgataaaaag ataaaacacc tagattttga aagaatattt gctgttttaa
     8041 aagaacacaa aatacaaatt ttggattcaa gtgaatattt tttccaaaat gtaaaaactt
     8101 ctgagaatat ttatttagag atgagggatt tagtatcttt ggaaaatcaa ggattagact
     8161 ttgaacattg tattttgagc ttgggggaaa gatgataata aatacattag gaccaactgc
     8221 aacagattgt ttttatgcaa taaatcgtat aaaattaaaa gtagatgtga ttgtactgta
     8281 tgatagtttt gatagtatag ttaattgctt tgataaatta aaagggcaat atatattatt
     8341 acctgtagct ttcgagagta gtattaaaaa ttatagttgg aaagatttca actttgaata
     8401 tcataagcgg attgaaattg tggattcttt tcactctttt actaagggaa tggttctaat
     8461 cgagaattgt aattataaaa ttaatagggc gattatccaa cctgcaactg agattttgat
     8521 gttaaactat ttaaagaaaa aaagtatgga tctgaggata gattttaccc atagtaaagt
     8581 tatggcaaat aaaaaatttc tggaagaagg ttatcgtttt tcaatagtaa gccaagaaac
     8641 gataattaat aatgatgata ttattatttg tgaaactttc tctccagaaa tgatttggtg
     8701 cttatataga gtgaaaggat agaaaatgtt ttctgaaatt attaagaaat atgatattgt
     8761 tacactgaaa gatagtggtt ttttgagagg tgattggttc ataggttcag cgttaatggc
     8821 tcatgactat gaaagcctta aggaagggat atatttctat ccccaggaaa caatttggac
     8881 aagaatcttg gatttagaat atataaatcc gtattgggaa atatataatc aaacttataa
     8941 tttcttatta gttaataaac aagattcatt agcaatgaat tttttaacta gtcttctaag
     9001 agaaatagaa gttatttcgt ctaaaacatt agattttgtt gttattactt caaacgaaca
     9061 cctaattagg aatttaattg atagagacta ttatattatt acaaaagaga ttccattttt
     9121 tattgaaaac tcaaaagttg gaaattattt taaaattttt gtgaaaaatg gaggacagtt
     9181 tattcctata attgactgta cggaatttaa gattcagtct aagaaatatt ttgagataaa
     9241 tattaataaa ttctacctga aacttttgga ttactttctt catggagaga ttccagaaaa
     9301 atttaaattt tttggaaata cctctaattt caatatagaa agcttgtttc tagaatttat
     9361 tgatagccaa gaaaatattc gagtagtttc cttgttggat tgtcttattc aattatcctc
     9421 taaaaatatt gaaatttcag gaaattataa agggcacaca gtgaaaaaaa tactaaaaaa
     9481 attcgcttta tactcagtaa ttaccaaact tgatataacg aaagtaaatc atttattgag
     9541 aaatgattat atctactttt taatgaagga aattgacaat attactaaaa aatatccaaa
     9601 gttaattcaa aagtacccta gagatatctt gagtgatagg tatggaataa caaatgaagt
     9661 atatagatac ttaatcggag agaatttaca tataaaaatt aatcataaat tagatgaggt
     9721 tagatatttt acagatattc catttattga tacttcactt tctattgaag agtttgacaa
     9781 aatagtttct aaaatattaa aaattaaagt gggagggtaa ctatgataag attaccaaat
     9841 aaatttaaag gtaataatat aactctagaa gttaaactaa ataaagcagt tgatgctagt
     9901 gtattatacc cagatgttaa gtctctagat caagaattgt atcgacaact acaatcagta
     9961 gaatcattct atcttacctt ttctgatatg tattcagaaa ttaatgaaaa taatgaaatc
    10021 ttatatacag aaataatctt taagatacct ctttgtattg gagaagatta ttttaatttt
    10081 ccggttgtat catatgtttc aaatccctat tcgttaataa gaggatttta tctaggtttt
    10141 cataaggaat tggactgtaa ctatgtattt gatgatgtag agcttcattt ttttagggaa
    10201 gggatttgtg aatttaactt cgaatttaaa aatcaaaatt caatcattac agcagaatta
    10261 ccaagggagt ataactatcc cttgatcttg tttaataatt ccaatctggt taatcaatat
    10321 ggaaaatata ctttgttaga catagacaaa tataaattag agtctagaaa gatttttgaa
    10381 tttccagaaa tttctatcgg taactttctt ggaagtgaag caaaatcaaa tagggtaatt
    10441 tttagccaag ataaatttca aattaatggc ataaagaata tggaggtaaa ttagcatgaa
    10501 atcattatta ataacaggtg gagcaggata cataggatca catacggttt tggacttgtt
    10561 agataataat tatgaagtaa caatcattga tgatttgagt aactctaaga aaaaagttat
    10621 tgagtctatt aagcagatat ccaagaagag tagaaatctt catttttata aaattgattt
    10681 aaaaaatgaa gaaaaattgg aaaatgtttt taagagacat aattttgatg gagtaattca
    10741 ttttgcaggg tataaagctg ttggagaatc cgtggttgaa ccattgaagt attatgaaaa
    10801 taatttatta tcaactataa atattttaaa actaatgaaa aaatataagg tatttaattt
    10861 tgtgtttagt tcatcagcta ctgtatacga aagtactcct atcatgccat tctatgagac
    10921 taatccatta aaagcttcaa acccgtatgg gagaacaaaa cagtatatag aagtactttt
    10981 aaatgatttg tttatttcga attcaaattg gaaaattgtt tgtctgaggt attttaatcc
    11041 attgggtgca catgaaagtg gtgatttagg agaggatcca aatggaattc cgaataatct
    11101 tgttccttac attacacaag ttgcaattgg aaaattacca tatttaaata tattcggagt
    11161 tgattacagt actcctgatg ggacttgtat aagggactat gttcacgtta acgatttagc
    11221 agacggacac agaaaagcat tagagtatat ttttaataca gatgaaggtt tatatgaagt
    11281 aatcaattta ggaagtggtg ttggttttag tgtatttgaa atcctacaca gcttagagag
    11341 tgtcataggc tcgtatattc catataagat aacttcaagg agagcaggag atatggacgt
    11401 ttcaattgca gatatttcaa aagcagaaga gctactggga tggaagccaa ggtatgatat
    11461 tatgaaaatg tgccaagata cgtggaaatg gcaacagaaa catccaaatg gatatgatga
    11521 ctaataattg aaaggattgg gattaacatg catatagtat tatttagata ttctgcacgg
    11581 gttgttaaac taaaatatct gtataacaga aatgtagtaa ttattgcacc tgaggttcaa
    11641 agaaaaaaat atgaagatta tctagctgaa ggaaataatc tacctaaggt cattttttta
    11701 gaagatttta ttctaccaaa tatcatctta gaaattagaa ggataagtca aaatacagaa
    11761 gttgagagta ttacaacctt gagtgaggaa gacatggata tagtaggttt tttgaatgat
    11821 cattttgtag aaaaaaatac tcactctgtg tctaatttat tatttaaaga caaatacttc
    11881 atgcgttcat ttttagttgg agtagtaaat caaccgtatt ttaggctttt agaatcagaa
    11941 aatgatttac gtgttttttg gaataattgt aaatcttctg ctgcaatttt aaaacctaga
    12001 aatgaagcag gaagtaatgg aataaaaaaa gtttacccta acgagaaaat tgattcagtg
    12061 tattttgaaa aaaactatat tatagaggaa tacattgata tcgataacat gataacatgt
    12121 gatggttatt caattggaag tgagattaag cgattttatg ttcacgaata tgaggaacta
    12181 ttgttcaata ccttaagttc tagtggatat tatcttgtaa ggactagttc gttatataat
    12241 gatagtgaaa aaattgaata catagaaaaa gcattggaag aatgtcgcaa agttttgaat
    12301 gttttttcta tcaattctga aataacccct tttcattttg aatggttcct tgaattatca
    12361 actggtaaaa tagtcttttg tgaagttgga aaaagatttg gagggggaga tattccccag
    12421 ttaattgagg atagtcatgg agttgatgta attaaagaat attgggatat tttgactaat
    12481 tcacaagtat tgaaaaaaat aaatttttct aaagtgattt ctagacctgc taatatctca
    12541 gcaacgtttg ctttatatag aaagcaaggt aaggttatcg aggtacctga tgaaaaagaa
    12601 ttggcttggg caaaaaaagt gtacatattt attaaaccaa atacttacta taaagtatct
    12661 gaaaatgtag tcgaaaattc aatgtttgtc caatttaatt gcaaaaatag ttgtgaattt
    12721 gagaaaaggt tagatgaact taagcacata tcacaaaagt ttaaatatgt gattactgat
    12781 tcgggagaat aaaatgatta gagaagaaca tcacaatatt ctatccattg tagctagtag
    12841 gatgatatct cgaatcggag atatcatgtt tgatttcgcc aataatacct ttcttgctgg
    12901 tcttaatcca acatctctat cagtggttgc aatttatcaa tcattagaaa gtatgatagg
    12961 tgttctattt aatttatttg gtggagttat tgcagatagt ttcaagcgga aaaaaattat
    13021 tattactaca aatatcttat gtggtattgc ttgcataact ctttcattta tatcccaaga
    13081 aaaatggttg gtttatgcga tagtcataac aaatgtcatt ttggctttta tgagtgcttt
    13141 ttcagggcca tcatacaaag cttttacgaa agaaattgta aaaaaggaca gtatatcata
    13201 acttaattca ttgctagaaa caacaagtac tgtgattaaa gtaacaattc ctatgattgc
    13261 aattttctta tataagttac ttggaataca tggtgtgtta ttactagatg gattatcgtt
    13321 tttaattgct gcctcactaa ttttcttcat tactcctgta aatgaggagg tggatacaaa
    13381 agagaatatg acgataagag gaatctttga tgatttaaaa ataggattta cgtatgtata
    13441 tagtcataaa caaattctca ctataattgc cctttcagca cttgttaact ttttcctagc
    13501 agcctataat ttgttgctgc catacagtaa tcaaatgttt ggaagtattt caagtgggct
    13561 atatggaacc tttttaacag ccgaagcgat tggtggcttt attggtgcga tattaagtgg
    13621 atttatcaat aaatccttgt caagcaaacg tttaatgctc tttttagcat attcaggttt
    13681 gatgttaatg ctaacagcgc cgatctatta tatgttccgc aacgtcatta ttttagcctt
    13741 tactccagca ttatttagtc tatttctttc catttttaat atccaatttt tctctattgt
    13801 tcaaagagac gtagataatg agtttcttgg cagagtattt ggaatcatct ttacggtagc
    13861 tattcttttt atgccactag gtactgtttt tttctcagta gttttaaatc ctaacaatac
    13921 ttttaatttt tttattattg gtgtatctat tacgatatta tcgctaatat ttagcacgct
    13981 attgaagagg tatgatagaa gttgatagat gataaaaaat agctgatata gagaatttag
    14041 agcgcctttg gaatatattt ttggaattta atcaatcaca gttgaatgtg aagggcaatc
    14101 ctttttagaa gaatacaatc aagataccat tatgctattt ctttagttca gttaaaatat
    14161 tgagaagtat tacttttatt gaaaaagcat cacaaaggac tccaattaat ttttaatgat
    14221 ttttctaatc taattttgtg gttattgaca aataaagtct agttaattgc tttgaaatcc
    14281 atggagtggt ctatatacat ctgttaatgc aacggaaaat tttattgata agtagggggt
    14341 ggctattatt cagcttttag gttctgaaag taagagattc acattagaaa tatcatgttg
    14401 accatttttc aatttgctgg ttagtagtaa tctggacatc attaatccct tccttaacaa
    14461 aattatgtga cttttgttac cggattactg ctgatttttt aatagcttat aacatcttta
    14521 gacggttaat agattttgac cgtctttctt aatattgtct tacctataat agatatgctt
    14581 atgagatatg tttaataaat taattttagt tcaaaatgtc cagtttggac actttgaatg
    14641 atttcttagt tttatatatt atacttttct caggagaaag ctagatgtac agacgtttga
    14701 gagatttgag ggaagatcac gatttgaccc aaaaacaaat agctaaaata ctttcgttta
    14761 cagactcagc ttatgctaaa attgaacggg gtgagcatac gttaacagca gatatattgg
    14821 taactctctc aaacttttac gatgtcagta cagactacct attgggattg acggattttc
    14881 ctgataaaat tcgctttaga aaataatctc ctcaatttca tagagtgtga aaatgcgaag
    14941 atttttttta tttgttcttt gacaattgaa tagtccaaaa tggtactttc ctcatttgtg
    15001 gagcagattt gaatggttcg ccatgataag agcgatatta aaaccatcaa taaaatagag
    15061 cgatacttta tatgccatga tacaaatgat atacaatgat acttctgacc gttcaggctg
    15121 ccaccgtaaa agagcagcaa gtgaaattct tatgatgact tcatcagtca tgccatgttg
    15181 aatgtgtgag tttgttagat aaacgcaatt aatcctcaaa aggttccccg aaccttttga
    15241 gttctacaga cgcatcacgt ggagtgtgta agcttgttgc taaaagcgta aaaaccttgg
    15301 aacgaaagga ataatagact tcctgcgaaa caaaaatata atacaataaa actatgaatg
    15361 atgaagcaag taaacaattg agcgatagcc gtttcaagat ccttgtaggt gttcagcgca
    15421 cgacttttga agagatgtta gcggtgttaa aaacagctta tcaacgtaaa cgcgcaaaag
    15481 gtggacgaaa aagcaaatta agcctagacg atctccttat ggtaactatt caatacatgc
    15541 gagaatagcg cacttatgaa caaattgcgg ctgattttgg cattcacgaa agcaacataa
    15601 ttagtcggag tcaatggatt gaagcaactc ttattcaaaa tggttttacg atttcaaatt
    15661 ctgccttaat tctgtaaaaa cagtaaaatt cgaaggattg taaggtaaga gtttttttct
    15721 ttctgaaaaa atggtataat agcaatcaaa actagaaaat aaaacggaat ttggaacaga
    15781 tttgtctgta tcctagtaga gtggtgatac tatgaagatt agtaagaggc acttattaaa
    15841 ttattccatc ttgattccct acttgctttt atctattttg ggcttgattg tggtctattc
    15901 gaccaccagt gctattttaa ttgaagaagg caagagcgcc ttgcagttgg ttcgaaacca
    15961 aggaatcttt tggattgtta gtttgatact gattgcctta atttataaat tgagactaga
    16021 ttttttgaga aatgagcgac taatcatttt agttatatta atagaaatgc ttttattgtt
    16081 cttggctcgt tttattggta tttcagtaaa cggggcatac ggttggattt cggttgcagg
    16141 agtaactatt cagccagctg agtacttaaa aatcattatt atttggtatt tagctcaccg
    16201 attctccaaa cagcaagaag aaatagctac ttatgatttt caagttttga ctcaaaatca
    16261 atggcttccc cgtgctttta atgattggcg attcgttctc ctagttctga ttggaagttt
    16321 gggaattttc cctgatttag gaaatgcgac tattttagtc ttggtttcct tgattatgta
    16381 tacagttagt ggaatcgctt atcgctggtt ttcaaccatt ctggcgctcg tatctgccac
    16441 ttctgtcttt gtcttgacca ctatcagcct aatcggtgtt gagacctttt caaaaattcc
    16501 agtatttggc tatgtagcca agcgctttag tgcctttttt aatccttttg ccgatcgtgc
    16561 tgatgcaggt caccagttag ctaattctta ttttgccatg gtcaatggcg gttggtttgg
    16621 tctaggtctt ggaaactcga ttgaaaaacg aggttatttg ccagaagctc atacagactt
    16681 tgtcttttct atcgtgattg aagaatttgg ctttgttggt gccagtctta ttttagctct
    16741 cttgtttttc atgattttgc ggattatctt ggtcggtatc cgagcggaga atcctttcaa
    16801 tgccatggtt gcactcggtg tcggagggat gatgttggtt caggtatttg tcaatatcgg
    16861 agggatttcg ggcttgattc catctacagg agtgactttc cccttcttat cccagggtgg
    16921 aaatagtctt ctagtcttat cagtggcagt agcctttgtc ttaaatattg atgccagtga
    16981 aaaacgcgct aaattgtacc gagaattgga aaatcaacca atgaaccttc tgttgaagta
    17041 ggataaagaa aggatagttt atgtctcttc aaaaattaga aaattatagt aataaaagtg
    17101 ttgtgcaaga agaagtcttg attctaacag aattactgga agatattact aaaaatatgc
    17161 ttgccccaga gacctttgaa aaaataatac agttgaaaga attatcaacg caggaagatt
    17221 atcaaggtct aaaccgtcta gtgactagct tatcaaatga tgaaatggtc tatatttcac
    17281 gctatttctc tatcttgcct cttttgatta atatttcaga ggatgtggat ttagcttatg
    17341 aaatcaatca tcaaaataat attgatcagg actatttagg taaattatct acaacgatta
    17401 aattggtagc agaaaaggaa aatgccgttg agatcctaga acacttgaat gttgtccctg
    17461 ttttgacagc ccatccaaca caagtgcaac gcaaaagtat gttggattta acaaatcata
    17521 ttcatagtct tttgcgtaaa taccgtgatg ttaagttggg gttgatcaat aaagataaat
    17581 ggtacaatga tttgcgtcgt tacatcgaaa ttatcatgca gacagacatg attcgtgaga
    17641 aaaaattaaa agtgactaac gaaatcacga atgctatgga atattataac atctcctttt
    17701 tgaaagctgt acctcatttg acgacggagt ataagcgctt agcgcaagcg catggtctga
    17761 atttaaaaca ggctaaacca atcaccatgg gtatgtggat aggtggtgac cgtgatggaa
    17821 atccatttgt tacagcaaag accttgaagc agtctgcact cactcagtgt gaagtcatca
    17881 tgaactacta tgataaaaag atttaccaac tttatcgtga attttctctt tcaactagca
    17941 ttgtcaacgt cagcaagcaa gtcagagaaa tggctcgtca atccaaggat aactcgattt
    18001 accgcgaaaa agagctttac cgtcgtgcct tgtttgatat tcaatcaaaa attcaggcaa
    18061 ctaaaaccta tctgattgag gatgaagaag ttgggactcg ttatgaaacc gccaatgatt
    18121 tctacaagga tttgattgcc attcgagatt ctctactaga aaataagggc gagtccttga
    18181 tttcaggtga ttttgtggaa ttattgcagg cagtagagat atttggtttt tacttagcat
    18241 caattgatat gcgacaagac tctagcgtct atgaagcctg tgtggcagaa ctcttgaaat
    18301 cagcaggaat tcattctcgt tatagcgagt tgagcgaaga agaaaagtgt gaccttctct
    18361 tgaaagaatt agaagaagat ccccgaattc tttctgcgac tcacgcagaa aaatcagaat
    18421 tattagcaaa agaattagct atttttaaga cggctcgtgt tttgaaagat aagttgggag
    18481 atgatgtcat ccgtcagacc atcatttcac atgcaaccaa cctttctgat atgctagaat
    18541 tagctattct gttaaaagaa gtaggactgg tggatacgga aagggcgcgt gttcagattg
    18601 ttcccctttt tgaaacaatt gaagacttgg atcattcaga ggaaacaatg agaaaatatc
    18661 tttctcttag ccttgccaaa aaatggattg actcacgaaa taactaccaa gaaatcatgc
    18721 ttggctactc tgacagtaat aaagatggcg gttacttgtc atcatgttgg accctctaca
    18781 aggctcaaca acaattgact gctattggag atgaatttgg cgttaaggtt accttcttcc
    18841 atggtcgtgg tggtactgtc ggtcgtggtg gtgggccaac ctatgaagcc attacatctc
    18901 aaccgctcaa gtctatcaag gatcgtatcc gtttgacgga gcagggtgaa gtaattggga
    18961 ataaatacgg taacaaagac gccgcttact ataaccttga aatgctagta tcggcagcta
    19021 ttaaccgtat gattactcag aagaagagcg ataccaatac cccaaatcgt tatgaagcca
    19081 ttatggatca agtagtggac cgtagttacg atatctaccg tgatttggtc tttggtaatg
    19141 agcatttcta tgattatttc ttcgagtcaa gtccaatcaa ggctatttca agttttaata
    19201 ttggttctcg tccagccgct cgtaagacta ttactgaaat cggtggtttg cgtgccatcc
    19261 cttgggtatt ctcatggtca cagagtcgtg ttatgttccc tggatggtac ggggttggtt
    19321 caagcttcaa ggaatttatc aataaaaatc cagagaatat tgctatctta cgagatatgt
    19381 accaaaattg gcctttcttc caatcgcttc tttcaaatgt tgatatggtt ttgtcaaaat
    19441 caaatatgaa tattgctttt gaatatgcta aactttgtga agacgagcaa gttaaggcca
    19501 tctatgagat tattttaaat gaatggcaag ttactaagaa cgttatcttg gctattgaag
    19561 gacatgacga actcttagct gacaatccat atctaaaagc tagtctggat taccgtatgc
    19621 cttactttaa tattctcaac tatattcagt tagagttgat taaacgccaa cgtcgtggag
    19681 aattgtccag tgatcaagaa cgattgattc atatcaccat caacggaatt gcgacaggat
    19741 tgcgtaattc aggttgataa ttttcaagag tgaatgctaa aagtgaatat caaaaaaatt
    19801 ctaatagact attgacaagt agtttaaaaa tgatataatt taaccattca gaaaagtaat
    19861 catacaaact ttttagagag tctgtggtag ctgaaaacag ataagtggcg atgatgaaaa
    19921 ttgggctgaa tgctatttag aatttgaaat tataaaaatt cggtaagcac accttacagt
    19981 gcatctcgtt attgcgagac tgagcgatag ggaaattccc tataattgag gtggtaccgc
    20041 gcatcgacgt cctcacacaa gttttttgtg tgaggatttt tttgatggag gttagtatgg
    20101 aaagaaaacg atggcgtcgc ttgtttagat aagtgaaata tgttaaagga aataaaaagg
    20161 agaaacagaa tgaaaaataa acgtttaatt ggaattattg ctgcattagc agtcttagta
    20221 gcaggaagct tgatttattc ttcaatgaat aaatcagaag ctcagaataa taaggatgag
    20281 aagaaaataa ctaagattgg tgtgcttcaa tttgtgagcc atccatccct tgatttgatt
    20341 tataaaggga tccaagatgg acttgcagaa gaaggatata aagatgatca agttaaaatt
    20401 gattttatga actcagaagg tgaccaaagt aaggttgcga caatgagtaa acaattggtt
    20461 gcaaatggga atgaccttgt ggttggtatc gcaacaccag cagcccaagg gttggctagt
    20521 gcaacaaaag acctaccggt tatcatggcc gctattacag acccaattgg tgctaacttg
    20581 gttaaagatt tgaaaaaacc aggtggcaac attacagggg tatctgacca caatccagct
    20641 caacaacaag ttgaactcat caaggctctg acaccgaatg tgaaaacaat cggagctctt
    20701 tactcaagta gcgaagacaa ttcaaaaaca caggtcgaag aatttaaggc ttatgctgaa
    20761 aaagcaggtc tgacagtgga aacatttgca gttccttcaa caaatgaaat tgcctcaact
    20821 gtcactgtta tgactagcaa ggtagatgct atttgggttc caattgataa caccattgca
    20881 tcaggatttc caacggttgt ctctagcaat caaagttcta agaaaccaat ttatcccagt
    20941 gcgacagcta tggtagaagt aggtggtttg gcatcagttg taattgacca acatgacctt
    21001 ggtgtggcaa caggtaaaat gattgtgcaa gtcttgaaag gtgcaaaacc agccgatacc
    21061 ccagtcaatg tcttttcaac tggtaagtca gtcatcaata aaaaaatagc acaagaacta
    21121 ggtattacta tccctgagtc tgttctcaaa gaagcaggac aagtcatcga ataaataagg
    21181 tagggaggag gagactcttc ccatttttta aaaagatgaa tatagaaagg attaaataaa
    21241 atatgattgt ttccattatt tctcaaggat ttgtctgggc tattctaggt ctgggaatct
    21301 ttatgacatt taggatttta aactttccag atatgacgac agaaggttcc ttccctcttg
    21361 ggggagctgt tgctgtcact ttgataacca aaggcgtgaa cccattttta gcgacacttg
    21421 ttgctgtagg agcaggttgt ttggctggaa tggcagcagg ccttctttat acaaaaggga
    21481 agatcccaac cttgctctca gggattttgg tgatgacttc ttgtcactca atcatgctct
    21541 tgattatggg acgtgcgaat ttaggcctgc ttggaaccaa gcaaattcag gatgttttgc
    21601 cttttgattc ggatttgaat caactcttga caggtctcat ctttgtgagt attgttattg
    21661 ctctcatgct ctttttcttg gacactaaac tcggacaagc ctatattgct acaggggata
    21721 atcctgatat ggctagaagt ttcgggattc atactggacg catggagctc atgggcttgg
    21781 tcttatcaaa tggtgtgatt gcccttgcag gtgccctcat tgctcagcaa gaaggttatg
    21841 ccgatgtgtc tcgagggatc ggggttatcg ttgtggggct tgcaagtttg attattggag
    21901 aagttatttt caagagtttg agcttggcag agcgtttggt tactatcgtt gtaggttcta
    21961 tcgcttatca atttttagtg tgggcagtta tcgcacttgg ctttaataca agttaccttc
    22021 gtttatacag tgccttgatt ttagcagtct gcctcatgat tccaacattt aagcaaacaa
    22081 tcttgaaagg agccaagtta agcaaatgac agcaattgta gaattaaaaa atgcaaccaa
    22141 aatcgttaaa aatggctttg atgaagaaaa gattatttta aatgatgttt ccttagaaat
    22201 ttttgaacgg gactttatca cgattttggg cggaaatggt gctggaaaat caaccctctt
    22261 taacactata gcagggacct tatcactaac tagtggaact atccgtattt taggtgaaga
    22321 tctcactaag ttttcacccg agaagcgtgc caagtacctg tctcgtgtct tccaagatcc
    22381 aaagatgggg acagctcccc gtatgacggt cgctgaaaat cttttaatcg ccaagtttcg
    22441 tggtgaaaag cgtggattgt taccacgacg cttgactagc tataaggatg aatttcaggt
    22501 aaccattgaa aaagtaggaa atggtcttga gaaacacttg aatacaccga ttgagttctt
    22561 atcaggtgga caaagacagg ctttgagtct cttgatggca accttgaagc gacctgaatt
    22621 actcctgtta gatgagcata ctgctgccct ggatccaaag actagtgttg ctttgatgga
    22681 attgacagat gaatttgtta agaaagatca gctaacagcc cttatgatta ctcatcatat
    22741 ggaagatgct ctcaaatacg gcaatcgctt gattgtcatg aaagaaggac ggattatcca
    22801 agatttaaac caagaagaaa aagcaaaaat gaaaatctct gattattatc aactctttga
    22861 ataaagtagg gaaaatgagt gaaatagttt actttttttc tgaaataaag tatactatat
    22921 atagtatact atgataacat ggaggtattg tgtatggttg acaaacaagt cattgaagaa
    22981 atcaaaaaca atgccaacat tgtggaagtc ataggagatg tgatttcttt acaaaaggca
    23041 ggacggaact atctagggct ctgtcctttt catggcgaaa aaacaccatc tttcaacgtt
    23101 gtagaggata agcagtttta tcactgtttc ggttgtggtc gctcaggtga tgtctttaag
    23161 ttcatcgagg agtaccaagg ggttcccttt atagaggcag tccaaatctt aggtcagcgt
    23221 gttggaattg aggttgaaaa accgctttat agtgagcaga agtcagcctc acctcaccaa
    23281 gctctttatg atatgcacga agatgcagcc aaattttacc atgctattct catgacaacg
    23341 actatgggag aagaggccag aaattacctt tatcagcggg gtttgacaga tgaagtgctt
    23401 aaacattttt ggattggttt agcacctcca gaacgaaact atctctatca acgtttgtct
    23461 gatcagtatc gtgaagagga tttactggat tcaggcctgt tttatctctc ggatgccaat
    23521 caatttgtag acacctttca caatcgcatt atgtttcccc tgacaaatga ccaaggaaag
    23581 atcattgcct tctcaggtcg tatctggcaa aaaacggatt cacaaacttc taagtataaa
    23641 aacagccgat cgactgcaat ttttaacaaa agttacgaat tatatcatat ggatagggca
    23701 aaaaaatctt ctggaaaagc tagtgagatt tacctgatgg aaggattcat ggatgttatt
    23761 gcagcctatc gggttggaat cgaaaatgct gtggcgtcga tgggaacggc cttgagtcga
    23821 gagcatgttg agcatctgaa aaggttaacc aagaaattgg ttcttgttta cgatggagat
    23881 aaggctgggc aagccgcgat attgaaagca ttggatgaaa ttggtgatat gcctgtgcaa
    23941 atcgtcagca tgcctgataa cttggatcct gatgagtatc tacaaaaaaa tggtccagaa
    24001 gacttggcct atctattaac gaaaactcgt attagtccga ttgagttcta cattcatcag
    24061 tacaaacctg aaaacagtga aaatctgcag gctcagattg agtttattga aaaaatagct
    24121 cccttgattg ttaaagaaaa gtccatcgct gctcaaaaca gctatattca tattttagct
    24181 gacagtctgg cgtcctttga ttatgcccag attgagcaga ttgttaatga gagtcgtcag
    24241 gtgcaaaggc agaatcgcat ggaaagaatt tccagaccga cgccaatcac catgcctgtc
    24301 accaagcagt tatcggctat tatgagggca gaagcccatc tactctatcg gatgatggaa
    24361 tcccctcttg ttttgaacga ttaccgtttg cgagaagact ttgcatttgc tacacctgaa
    24421 tttcaggtct tatatgactt gcttggccag tatggaaatc ttcctccaga agttttagca
    24481 gagcagacag aggaagttga aagagcttgg taccaagttt tagctcagga tttgcctgct
    24541 gagatatcgc cgcaggaact tagtgaagta gagatgactc gaaacaaggc tctcttgaat
    24601 caggacaata tgagaatcaa aaagaaggtg caggaagcta gccatgtagg agatacagat
    24661 acagccctag aagaattgga acgtttaatt tcccaaaaga gaagaatgga gtaataatgg
    24721 caacaaaaca aaaagaagta acaacatttg acgtacaggt agcagaattt atccgtaatc
    24781 ataagcaaaa agggacagca acagatgatg aaatcaatgc aagtttggtt attcctttta
    24841 ccttggacgc tgatgggatt gaagatctct tgcaacggat tcaggatgca ggaatttcta
    24901 tcacagataa cgaaggaaat ccaagtgcgc gtgttcttag caatgaagaa gaaccagaac
    24961 tcagcgatga ggacttgatt gggtcaactt ctgctaaggt caatgaccct gtccgtatgt
    25021 acttgaaaga aataggggtc gttcctctct tgaccaatga agaggagaaa gagttggcac
    25081 tggctgttga agctggtgat atcgaagcca aacaacgtct tgcggaagcc aatcttcgtt
    25141 tggttgtttc cattgccaaa cgctatgtcg gtcgtggtat gcagttcctt gacttgattc
    25201 aagaaggaaa tatgggcttg atgaaggcgg ttgacaagtt tgactattct aaagggttca
    25261 agttttcaac ttatgcaact tggtggattc gtcaggctat cactcgtgct attgcggacc
    25321 aagctcgtac catccgtatc ccagttcaca tggttgaaac tatcaataaa ttggttcgtg
    25381 aacagcggaa tctccttcaa gaattggggc aagatccgac accagaacag attgctgaac
    25441 gaatggatat gacacctgat aaggttcgtg aaatcttgaa gattgcccaa gaaccagtat
    25501 ctcttgaaac tcctatcggt gaagaggacg atagccacct cggagacttt atcgaagatg
    25561 aagtgattga aaatccagtg gattatacga ctcgtatcgt cttgcgtgag caattggatg
    25621 aaatcttaga tactcttaca gaccgtgaag aaaatgttct gcgtctacgt tttggactag
    25681 atgatggaaa aatgcgcaca cttgaagatg tggggaaagt ctttaacgta actcgtgagc
    25741 gtatccgtca gattgaagca aaggctttga gaaaactacg ccaaccaagt cgtagcaaac
    25801 cgcttcgtga ttttattgaa gactaagagt gaggaaaata tggcttatac agaagagcaa
    25861 attgaaaaca tcaaaacacg gattttaaca gccttggaag aagtcatcga ccctgagttg
    25921 ggaatcgata ttgtcaatct tggtttgatc tatgagattc gttttgacgg tgacacaggg
    25981 caaacagaga ttgacatgac tttgacaact atgggttgtc ccttagcaga ccttttgaca
    26041 gaccagattt atgatgctat gatagaggtt ccagaagtaa cggatactga ggttaaatta
    26101 gtctggtatc cagcctggac agttgaaaaa atgagtcgct atgcccgcat tgccctaggc
    26161 attaagtaaa catataaaag catgtgagag actgttggaa aagcgaggaa atttcccctc
    26221 ttttcctcta gtctctcctt tcttttgctg attttattca aagaaaatga tataatagta
    26281 gttatggaga aaaagaaatt acgcatcaat atgttgagtt caagtgagaa agtagcagga
    26341 cagggagttt caggtgctta ccgtgaatta gttcgtcttc ttcaccgtgc tgccaaggac
    26401 caattgattg ttacagaaaa tcttccaatc gaggcagatg tgactcactt tcatacgatt
    26461 gattttccct attatttatc aaccttccaa aagaaacgct cagggagaaa gattggctat
    26521 gtgcatttct tgccagctac acttgaggga agtttgaaaa ttccattttt cttaaaggga
    26581 attgtgaaac gctatgtatt ttctttttac aaccggatgg agcacttggt tgtggtcaat
    26641 cctatgttta ttgaggattt ggtagcagct ggtattccac gtgaaaaagt gacctatatt
    26701 cctaactttg tcaacaagga aaaatggcat cctctaccac aagaagaggt agttagactg
    26761 cgcacagatc ttggtcttag tgacaatcag tttatcgtag taggtgctgg gcaagttcag
    26821 aaacgtaaag ggattgatga ctttatccgt ctggctgagg aattgcctca gattaccttt
    26881 atctgggctg gtggcttctc ttttggtggt atgacagatg gttatgaaca ctataagaaa
    26941 attatggaaa atccccctaa aaatttgatt tttccaggca ttgtatcgcc agagcggatg
    27001 cgcgaattgt atgctctagc ggatcttttc ttgttgccta gttacaatga gctctttcct
    27061 atgactattt tagaagctgc gagttgtgag gctcctatta tgttgcgtga tttagatctc
    27121 tataaggtga ttttggaggg aaattatcgg gcgacagcgg gtagagaaga gatgaaagag
    27181 gctattttgg aatatcaagc aaatcctgct accttaaaag atctcaaaga aaaggctaag
    27241 aatatttcca gagagtattc tgaagagcat ctgttacaaa tctggttgga cttttatgag
    27301 aaacaagccg ctttagggag aaagtaaaaa gtgaggtaat ctatgcgaat tggtttattt
    27361 acagatacct attttcctca ggtttctggt gttgcgacca gtattcgaac cttgaaaaca
    27421 gaacttgaaa agcagggaca tgctgttttt atctttacga cgacagataa ggatgtcaat
    27481 cgctacgaag attggcaaat tatccgcatt ccaagtgttc ctttctttgc ttttaaggat
    27541 cgtcgctttg cctaccgagg ttttagcaag gcacttgaaa ttgctaaaca gtatcagcta
    27601 gatattatcc atactcagac agaattttct cttggcctgt tggggatttg gattgcgcgt
    27661 gaattgaaaa ttccagtcat ccatacctat cacacccagt atgaagacta tgtccattat
    27721 attgctaagg ggatgttgat ccggccgagt atggtcaagt atctggttag aggtttcctg
    27781 catgatgtgg atggggttat ttgccctagt gagattgtcc gtgacttgct atctgattat
    27841 aaggtcaagg ttgaaaaacg ggtcattcct actggaattg aattagccaa gtttgagcgt
    27901 ccggaaatca agcaggaaaa tttgaaagaa ctgcgtagta aactagggat tcaagatggt
    27961 gaaaagacgt tgcttagtct ttcgagaatc tcctatgaaa aaaatattca agcagtttta
    28021 gtagcctttg ctgatgttct gaaagaggaa gacaaggtta aactggtagt agctggggat
    28081 ggcccttatc tgaatgacct caaagagcaa gcccagaacc tagagattca agactcagtc
    28141 atctttacag ggatgattgc tcctagtgag acggctcttt actataaagc ggcggatttc
    28201 ttcatttcgg catcgacaag cgaaacgcaa ggtttgacct acttggaaag cttagccagt
    28261 ggaacacctg tcattgctca cggaaatcct tatttgaaca acctcatcag tgataaaatg
    28321 tttggaacct tgtactatgg agaacatgat ttggctggtg ctatttcgga agccctgatt
    28381 gcaacaccag acatgaatga gcatacctta tcagagaaat tgtatgagat ttcagctgag
    28441 aactttggga aacgagtgca tgagttttat ctggatgcca ttatttcaaa taacttccag
    28501 aaagatttgg ctaaagatga tacggtcagt cagcgtatct ttaagacagt tttgtatctt
    28561 ccgcaacagg tggttgctgt acctgtaaaa ggatctagac gcatgttgaa ggcttcaaaa
    28621 acacagttga tcagtatgag agactattgg aaagaccatg aagaatagaa agaggaacag
    28681 ctatgaaaaa aacaattaat gagaagcggt cgtgataaaa agattgcggg tgtttgtgct
    28741 ggggtggccc attatctgga tatggatccg actatcgttc aagtcatttg gggtgttctt
    28801 acttgctgtt acggagctgg aattgtagct tacattattt tatggattat cgcaccagta
    28861 gcaactgact attgaaaact agctcaattc atgctaagat aatagaaaat agaatgtaac
    28921 gaaggagaga aaaatggcat ttggagataa tggaaatcgt aaaaaaacta tgtttgagaa
    28981 aataaccttg tttatcgtga ttatcatgct agtagcaagt ttattgggaa tttttgcaac
    29041 tgcaattggt gccctcagta atctataaaa tagattcaag aaaatttagt gactgggatt
    29101 tcccagccct tttttaaagt gagaagaaat aatgagtatg tttttagata cagctaagat
    29161 taaggtcaag gctggtaatg gtggcgatgg tatggttgcc tttcgtcgtg aaaaatatgt
    29221 ccctaatgga ggcccttggg gtggtgatgg tggtcgtgga ggcaatgtgg tcttcgttgt
    29281 agacgaagga ctacgtacct tgatggattt tcgctacaat cgtcatttca aggctgattc
    29341 tggtgaaaaa gggatgacca aagggatgca tggtcgtggt gctgaggacc ttagagttcg
    29401 agtaccacaa ggtacgactg ttcgtgatgc ggagactggc aaggttttaa cagatttgat
    29461 tgaacatggg caagaattta tcgttgccca cggtggtcgt ggtggacgtg gaaatattcg
    29521 tttcgcgaca ccaaaaaatc ctgcaccgga aatctctgaa aatggagaac caggtcagga
    29581 acgtgagtta caattggaac taaaaatctt ggcagatgtc ggtttagtag gattcccatc
    29641 tgtagggaag tcaacacttt taagtgttat tacctcagct aagcctaaaa ttggtgccta
    29701 ccactttacc actattgtac caaatttagg tatggttcgc acccaatcag gtgaatcctt
    29761 tgcagtagcc gacttgccag gtttgattga aggggctagt caaggtgttg gtttgggaac
    29821 tcagttcctc cgtcacatcg agcgtacacg tgttatcctt cacatcattg atatgtcagc
    29881 tagcgaaggc cgtgatccat atgaggatta cttagctatc aataaagagc tggagtctta
    29941 caatcttcgc ctcatggagc gtccacagat tattgtagct aataagatgg acatgcctga
    30001 gagtcaggaa aatcttgaag aatttaagaa aaaattggct gaaaattatg atgaatttga
    30061 agagttacca gctatcttcc caatttctgg attgaccaag caaggtctgg caacactttt
    30121 agatgctaca gctgaattgt tagacaagac accagaattt ttgctctacg acgagtccga
    30181 tatggaagaa gaaacttact atggatttga cgaagaagaa aaagcctttg aaattagtcg
    30241 tgatgacgat gcgacatggg tactttctgg tgaaaaactc atgaaactct ttaatatgac
    30301 caactttgat cgtgatgaat ctgtcatgaa atttgcccgt cagcttcgtg gtatgggggt
    30361 tgatgaagcc cttcgtgcgc gtggagctaa agatggggat ttggtccgca ttggtaaatt
    30421 tgagtttgaa tttgtagact aggagactgg tatgggagat aaaccgatat ctttccgaga
    30481 tgcggatggt aattttgttt ccgccgcaga cgtttggaat gaaaagaaat tggaagaact
    30541 atttaatcgt ctcaatccaa atcgtgcctt gagattggca cgaactaaaa aggaaaatcc
    30601 atctcagtaa agaagctaaa aaatcccgtg cctcatcaga cacgggattt tgtggtacga
    30661 caggcatgta tagcaaactg aatctggaat agcacagcat atcttctaaa atattgttat
    30721 aaattgattt gaatttcaaa attaaattgt ttgattctta tttcaatttg ttatagtata
    30781 tctgatgtca aagttctcgg cgagtcaaat agcgattccc aagcctgact atcgtgaggt
    30841 agcggattaa aatggtctgg ggatagaccg ttttaagtct gacgctggaa ataagaattg
    30901 tcagaagaag ggatagcgaa atcgtggctc tacgaacagg aacgttataa taaggcgtat
    30961 atagcggata agagggcctc aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg
    31021 taaatcacga gagtaattga attcgtacta agattttcta ttttcactgt aaccttttaa
    31081 cgtccttata tcttgtatac acgaggaaag atgtacgact tatcccgtga ggtctatcac
    31141 tataaagaga aaacgacaga tagaagtgat cctgagtcac ggttatcttt aaaatagatt
    31201 gtctgatagg acggtatgta taaaacgctt ctgtgaactg agagaagggg gagaagttct
    31261 tgctaaaatt tagttgaaca gccgtattcc gatacttaga taagagatct agtcttagct
    31321 cctactcggt ttcaggggat aaaaaagggg caatagcgat tcgagaaaga ttatactctt
    31381 cgaaaatctc ttcaaatcac gtcaatatcg ccttgccgta cgtgtaggat actgactacg
    31441 tcagt
//
LOCUS       DAVBOU010000024        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBOU010000024 DAVBOU010000000
VERSION     DAVBOU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.024"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ879_001175"
     CDS             289..2790
                     /locus_tag="VQ879_001175"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3143332.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ879_001176"
     CDS             2984..3679
                     /locus_tag="VQ879_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143333.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ879_001177"
     CDS             3691..4107
                     /locus_tag="VQ879_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143334.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ879_001178"
     CDS             complement(4922..5014)
                     /locus_tag="VQ879_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3143335.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ879_001179"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ879_001179"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3143336.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ879_001180"
     CDS             6127..6699
                     /locus_tag="VQ879_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3143337.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ879_001181"
     CDS             6930..7688
                     /locus_tag="VQ879_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3143338.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ879_001182"
     CDS             7697..8500
                     /locus_tag="VQ879_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3143339.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ879_001183"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ879_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3143340.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ879_001184"
     CDS             9794..11647
                     /locus_tag="VQ879_001184"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3143341.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ879_001185"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ879_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3143342.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRIAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFSQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ879_001186"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ879_001186"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3143343.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(15264..15341)
                     /locus_tag="VQ879_001187"
                     /pseudo
     CDS             complement(15264..15341)
                     /locus_tag="VQ879_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15398..16447
                     /locus_tag="VQ879_001188"
     CDS             15398..16447
                     /locus_tag="VQ879_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3143344.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ879_001189"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ879_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3143345.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ879_001190"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ879_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3143346.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ879_001191"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ879_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3143347.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ879_001192"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ879_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3143348.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ879_001193"
     CDS             24247..28638
                     /locus_tag="VQ879_001193"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3143349.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ879_001194"
     CDS             28740..29003
                     /locus_tag="VQ879_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3143350.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ879_001195"
     CDS             28996..29274
                     /locus_tag="VQ879_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3143351.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ879_001196"
     CDS             29295..29447
                     /locus_tag="VQ879_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143352.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ879_001197"
     CDS             29469..30710
                     /locus_tag="VQ879_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3143353.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ879_001198"
     CDS             30720..30950
                     /locus_tag="VQ879_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3143354.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8795 a         5923 c         7248 g         8996 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgttgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgaattgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc agtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagagtta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBOU010000025        27949 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBOU010000025 DAVBOU010000000
VERSION     DAVBOU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27949
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.025"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ879_001199"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ879_001199"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3143355.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ879_001200"
     CDS             complement(1995..2927)
                     /locus_tag="VQ879_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3143356.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ879_001201"
     CDS             complement(2924..3781)
                     /locus_tag="VQ879_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3143357.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ879_001202"
     CDS             complement(3785..5131)
                     /locus_tag="VQ879_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3143358.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ879_001203"
     CDS             complement(5144..5428)
                     /locus_tag="VQ879_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3143359.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ879_001204"
     CDS             complement(5432..7462)
                     /locus_tag="VQ879_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3143360.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ879_001205"
     CDS             7653..8660
                     /locus_tag="VQ879_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3143361.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ879_001206"
     CDS             8663..8863
                     /locus_tag="VQ879_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3143362.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ879_001207"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ879_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3143363.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ879_001208"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ879_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3143364.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ879_001209"
     CDS             complement(9784..11664)
                     /locus_tag="VQ879_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3143365.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ879_001210"
     CDS             complement(11658..12527)
                     /locus_tag="VQ879_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3143366.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ879_001211"
     CDS             complement(12611..15256)
                     /locus_tag="VQ879_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3143367.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ879_001212"
     CDS             complement(15347..16627)
                     /locus_tag="VQ879_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3143368.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ879_001213"
     CDS             16798..18882
                     /locus_tag="VQ879_001213"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3143369.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ879_001214"
     CDS             complement(18922..20601)
                     /locus_tag="VQ879_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3143370.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ879_001215"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ879_001215"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3143371.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ879_001216"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ879_001216"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3143372.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ879_001217"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ879_001217"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3143373.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ879_001218"
     CDS             24983..26494
                     /locus_tag="VQ879_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3143374.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ879_001219"
     CDS             26516..27847
                     /locus_tag="VQ879_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3143375.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
BASE COUNT         8235 a         6218 c         5365 g         8131 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaatt
//
LOCUS       DAVBOU010000026        27935 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBOU010000026 DAVBOU010000000
VERSION     DAVBOU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27935
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.026"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            393..1571
                     /locus_tag="VQ879_001220"
     CDS             393..1571
                     /locus_tag="VQ879_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3143376.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1885..2016
                     /locus_tag="VQ879_001221"
     CDS             1885..2016
                     /locus_tag="VQ879_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3143377.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2037..3587
                     /gene="dltA"
                     /locus_tag="VQ879_001222"
     CDS             2037..3587
                     /gene="dltA"
                     /locus_tag="VQ879_001222"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3143378.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3584..4828
                     /gene="dltB"
                     /locus_tag="VQ879_001223"
     CDS             3584..4828
                     /gene="dltB"
                     /locus_tag="VQ879_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3143379.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4842..5081
                     /gene="dltC"
                     /locus_tag="VQ879_001224"
     CDS             4842..5081
                     /gene="dltC"
                     /locus_tag="VQ879_001224"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3143380.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5074..6342
                     /gene="dltD"
                     /locus_tag="VQ879_001225"
     CDS             5074..6342
                     /gene="dltD"
                     /locus_tag="VQ879_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3143381.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6497..6937
                     /gene="adcR"
                     /locus_tag="VQ879_001226"
     CDS             6497..6937
                     /gene="adcR"
                     /locus_tag="VQ879_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3143382.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6937..7641
                     /locus_tag="VQ879_001227"
     CDS             6937..7641
                     /locus_tag="VQ879_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3143383.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7634..8440
                     /locus_tag="VQ879_001228"
     CDS             7634..8440
                     /locus_tag="VQ879_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3143384.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8450..9955
                     /gene="adcA"
                     /locus_tag="VQ879_001229"
     CDS             8450..9955
                     /gene="adcA"
                     /locus_tag="VQ879_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3143385.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(11117..11890)
                     /locus_tag="VQ879_001230"
     CDS             complement(11117..11890)
                     /locus_tag="VQ879_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3143386.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            12066..13469
                     /locus_tag="VQ879_001231"
     CDS             12066..13469
                     /locus_tag="VQ879_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3143387.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13584..14222
                     /locus_tag="VQ879_001232"
     CDS             13584..14222
                     /locus_tag="VQ879_001232"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3143388.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14234..14674
                     /locus_tag="VQ879_001233"
     CDS             14234..14674
                     /locus_tag="VQ879_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3143389.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14667..15098
                     /locus_tag="VQ879_001234"
     CDS             14667..15098
                     /locus_tag="VQ879_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3143390.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            15089..15559
                     /locus_tag="VQ879_001235"
     CDS             15089..15559
                     /locus_tag="VQ879_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3143391.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15584..16357
                     /locus_tag="VQ879_001236"
     CDS             15584..16357
                     /locus_tag="VQ879_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3143392.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16354..17154
                     /locus_tag="VQ879_001237"
     CDS             16354..17154
                     /locus_tag="VQ879_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3143393.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17213..19507
                     /locus_tag="VQ879_001238"
     CDS             17213..19507
                     /locus_tag="VQ879_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3143394.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19517..22633
                     /locus_tag="VQ879_001239"
     CDS             19517..22633
                     /locus_tag="VQ879_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3143395.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            22690..24456
                     /locus_tag="VQ879_001240"
     CDS             22690..24456
                     /locus_tag="VQ879_001240"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3143396.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            24602..25753
                     /locus_tag="VQ879_001241"
     CDS             24602..25753
                     /locus_tag="VQ879_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3143397.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            25898..26782
                     /locus_tag="VQ879_001242"
     CDS             25898..26782
                     /locus_tag="VQ879_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3143398.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(26900..26977)
                     /locus_tag="VQ879_001243"
                     /pseudo
     CDS             complement(26900..26977)
                     /locus_tag="VQ879_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            27181..27433
                     /locus_tag="VQ879_001244"
                     /pseudo
     CDS             27181..27433
                     /locus_tag="VQ879_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            27421..27711
                     /locus_tag="VQ879_001245"
     CDS             27421..27711
                     /locus_tag="VQ879_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143399.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
BASE COUNT         8791 a         4580 c         5912 g         8652 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aactaacttc ttagtactag ccaacaacga
      241 taatcataat tcctcctaaa attaggaata ataaaggcaa tagtttttgt tttttcatgt
      301 aaaaaacctc acttttgttt tctgctattt tatgctaaaa tattaaaaat caaatttaat
      361 tccaaagttt gtaactaaag ggggagcgct acatgtctaa ttcatttgtc aagttgttag
      421 tctctcaatt atttgcaaat ttagcagata ttttctttag agtaacaatc attgctaaca
      481 tatacattat ttcaaaatca gtaattgcca catcactagt tcctatctta ataggaatat
      541 cctcttttgt tgcgagtctt ttagttccgt tggttactaa aaggttagcg ctaaataggg
      601 ttttatcttt atctcaattt ggaaagacta tattattggc gatactggta ggaatgttta
      661 ccgtaatgca atccgtagcg cctttggtga cctatctatt tgttgttgca atttccatac
      721 tagatggttt tgcagcaccc gtttcctatg ctattgtgcc acgctatgcg accgatttgg
      781 gtaaggctaa ttcagcctta tcaatgactg gtgaagctgt tcaattgata ggttggggat
      841 taggtggact cttgtttgca acaattggtc tgttacctac cacgtttatc attttagtct
      901 tgtatatcat ttctagcttt ctgatgttat ttcttcctaa cgctgaagtg gaggtgttag
      961 agtcagaaac taatcttgaa attttgctca aaggttggaa gttagttgct agaaatccta
     1021 gattaagact ttttgtatca gcaaatttat tggaaatttt ttcaaatacg atttgggttt
     1081 cttccattat acttgttttt gtaacggagt tattaaataa aacggaaagt tactggggat
     1141 attctaatac agcatactct attggtatta taattagtgg cttaattgct tttaggctat
     1201 ctgaaaagtt ccttgctgct aaatgggaaa gtattctttt tcctcttgta gctatggcaa
     1261 tagtgacact gactattcta tattttccaa acgcacagat gtttttatta ttttcagctt
     1321 tagttggtat gttatcgcaa ctaaaagaag ttcctgaaag tgtatttctt caggaaacag
     1381 tagaggaaaa tcatttagtt aatgtctatt ccgttcttga agtgatttct acattagcat
     1441 tttcagtatt tgttttgcta atgagctata ttactgagag ttttggtatt agcatcagtt
     1501 tttggctatc agccatttgt ctgatgatag aagctatttt aatttatatc agacgagatt
     1561 attttaaatg agagagtggt taaaaagtct ttaaaaatca gaaaagcgca tagtatcagg
     1621 tgttgaaaaa acttgatatt gtgtgtttta ttatgggaag atttacttca ttgtctcctg
     1681 aaatggagtt ttgaggcagg atcactctat ttgaaaatat acatagaaaa actgtataat
     1741 ccttaaaata agctgaaatc tattggaaac atacggtaaa caattgaaaa gatactatat
     1801 aaagtggtac aatggtagaa aaataagcta gtaagaatca ctcttatttt agcgaaaaat
     1861 tacagaaatg aatggttttt cttgatgaaa cagagaaaag aattgtacct ctttcttggt
     1921 cggacagcct tgtattttct tatctttcta gggctgcttt acttctttag ctatcttggt
     1981 cagggtcaag gaagctttat ctataatgaa ttttaacttg aaggagaatc cctattgtgt
     2041 caaataaacc aatagcagat atgattgaaa ccattgagca ttttgctcag acacagccta
     2101 gctatcctgt ctataatgtt ttggggcagg aacacactta tggcgattta aaggctgatt
     2161 cggatagttt ggctgcagtc attgaccaac taggcttgcc tgagaagtct cctgtggttg
     2221 tttttggtgg ccaagaatat gaaatgttgg caacctttgt agcgctgact aagtcaggtc
     2281 atgcctacat tccaattgat agccattcgg ccttggagcg agtttcagct attttagaag
     2341 tagcagagcc aagcttgatt attgccattt cagcctttcc cttggagcag gtttctacac
     2401 caatgataaa tctagctcag gttcaagaag cctttgccca agggaataac tatgaaatca
     2461 cgcatccagt caagggagat gataattact acattatctt tacttctggt acgactggta
     2521 agcctaaggg agtgcagatt tcacatgata atctcctcag ctttacaaac tggatgatta
     2581 cggataagga atttgcgaca ccgagtcgtc cgcaaatgct ggcacagcca ccttattctt
     2641 ttgacttgtc tgtcatgtat tgggcaccga ccttggcact tggtggtacg cttttcactc
     2701 ttccttcagt catcactcag gactttaagc aactctttgc ggctatcttt tcattgccaa
     2761 tcgctatctg gacatcaaca ccatcctttg cagatatggc catgttgtct gaatacttca
     2821 acagtgagaa aatgcctgga atcacgcatt tctactttga tggtgaagaa ttgacggtca
     2881 aaacagctca aaaactgcgc gagcgtttcc caaatgcccg tatcatcaat gcttacggcc
     2941 caacagaagc gacagtagct ctgtcagcag ttgccgtgac agacgagatg ttagcgactc
     3001 tcaaacgcct accaatcggc tataccaagg ctgattctcc aacctttatc attgacgagg
     3061 aaggaaataa actgccaaat ggtgagcagg gagaaatcat tgtttctggg ccagctgttt
     3121 caaaaggtta tatgaacaat cctgaaaaaa cagcagaagc cttctttgag tttgaagatc
     3181 tgccagccta tcacacaggc gatgtgggaa ccatgacaga tgagggcttg cttctctacg
     3241 gcggacgcat ggacttccag attaagttta acggttaccg cattgagtta gaagatgtct
     3301 ctcaaaacct caacaagtct cgctttatcg aatctgctgt cgcagtaccg cgctataaca
     3361 aggaccacaa ggtacaaaat ctattggctt atgtcatctt aaaagacggt gttcgtgagc
     3421 agtttgagcg agatatcgat attaccaagg ccatcaagga agacctgaca gacatcatga
     3481 tgtcctatat gatgccatct aaattccttt accgagacag tttgccacta actccaaatg
     3541 gaaagattga catcaaagga ttgattaacg aggtgaataa gagatgatgg agttttttca
     3601 acagcttcct catttagagc catatggcaa tcctcagtat tttgtttatg tgattgctgc
     3661 aaccttgccc atctttatag gtctcttttt caagaaacgc tttgcctggt atgaagtgtt
     3721 ggtaagtctc ttctttattg tcaccatgtt ggtgggtgga aagaccaatc aactagctgc
     3781 cttgggtatt tacctttgct gggaaatatt gctcctgctt ttctacaagc attatcgaaa
     3841 aagcaaggat ggcaagtggg tcttctactt agttagtttt ctgtccctac ttccgattat
     3901 ctttgtcaag gtgcaaccag ctatcaatgg aacgcagtct ttgcttgggt tcttgggaat
     3961 ttcttacctt acctttcgtt cggttgggat tgtcatcgag ctgagagatg gagtgattaa
     4021 ggattttacc ctctgggaat tcctccgttt ccttctcttc atgccaactt tctcgagtgg
     4081 tccaatcgat cgctttaagc gatttaatga aaattatcag gctattcctg agcgagatga
     4141 gttgatggat atgctggatg aatctgtccg ctatatcatg tggggctttt tgtataagtt
     4201 tatcctagct catgttttag gagagacctt actacctcct ctgaagaatt tagccttgca
     4261 gtcaggtggc ttctttaatc tctatgcctt ggcagttatg tatacttttg gtctggaact
     4321 cttctttgac tttgcaggtt attctatgtt tgctttggcc atctcaaact tgatgggaat
     4381 ccgtagccct atcaacttta acaagccctt tttatcaagg gatttaaagg agttttggaa
     4441 tcgctggcat atgagtctgt ccttctggtt ccgtgacttt gtctttatgc gaatggtgat
     4501 ggtgttaacc agaaagaaag tctttaaaaa tcgtaatgta acctcaagca tggcctacat
     4561 tgtaaatatg ctgattatgg gattttggca tggtgtgacc tggtactata tcgcctatgg
     4621 actctttcat ggactaggct tggtcatcaa tgatgcctgg gttcgcaaga aaaaaacgct
     4681 caataaggaa cggaaaaaag cagggaaggc tgccctacct gagaatcgct ggattcagtt
     4741 gcttggcatg gttgtcactt tccatgttgt catgttgtca ttcttaatct tttctggatt
     4801 cttgaataat ctatggttta aaaaataaaa ggaaataaaa tatggatatc aaatcagaag
     4861 ttattgaaat tattgatgag ttgtttatgg aagatgtttc tgacatgatg gatgaagatc
     4921 tttttgatgc aggtgtcttg gatagtatgg gaacggttga gttgattgtg gagattgaga
     4981 accgttttga cattcgtgtc cctgtaacag agtttggtcg tgacgactgg aatacagcta
     5041 ataaaatcat agctggtatt gtggagctac aaaatgctta aacgcttatg gatgatcttc
     5101 ggaccggtct tgatcgctgg tttgttggtt tttctgctca ttttctttta tcctactgag
     5161 atgcatcata atctaggagc tgaaaagcgt tcagcagtgg ctactactat cgatagtttt
     5221 aaggagcgaa gtcaaaaagt cagagcacta tctgatccaa atgtgcgttt tgttcccttc
     5281 tttggctcta gtgaatggct tcgttttgac ggtgctcatc ctgcggtatt agctgagaaa
     5341 tacaatcgtt cctaccgtcc ttatctttta ggacaggggg gagctgcatc gcttaaccaa
     5401 tattttggaa tgcaacagat gttaccacag ctggagaata aacaagttgt gtatgttatc
     5461 tcacctcagt ggttcagtaa aaatggctat gatccagcag ccttccagca gtattttaat
     5521 ggagaccagt tgactagttt tctgaaacat caatctgggg atcaggctag tcaatatgca
     5581 gcgactcgct tactgcaaca gttcccaaac gtagctatga aggacctggt tcagaagttg
     5641 gcaagtaaag aagaattgtc gacagcagac aatgaaatga ttgaattatt ggctcgtttt
     5701 aatgaacgcc aagcttcctt ttttggtcag ttttcggtta gaggctatgt taactacgat
     5761 aagcatgtag ctaagtattt aaaaatcttg ccagaccagt tttcttatca ggcaatagaa
     5821 gatgttgtca aagcagatgc tgaaaaaaat acttccaata atgagatggg aatggaaaat
     5881 tatttctata atgagcagat caagaaggat ttgaagaaat taaaggattc tcagaaaagc
     5941 tttacctatc tcaagtcgcc agagtataat gacttgcagt tggttttaac acagttttct
     6001 aaatctaagg taaacccgat ttttatcatt ccacctgtta ataaaaaatg gatggactat
     6061 gctggtctac gagaggatat gtaccaacaa acggtgcaga agattcgcta ccagttggaa
     6121 agtcaaggtt ttaccaatat agcagatttt tctaaggacg gcggggagcc tttctttatg
     6181 aaggacacca ttcaccttgg ttggttgggt tggttggctt ttgacaaggc agttgatcct
     6241 ttcctatcca atcccacacc agctccgact taccatctga atgagcgctt tttcagcaaa
     6301 gattgggcga cttatgatgg agatgtcaaa gaatttcaat agataatata atatagaaga
     6361 gttcaagaat gaaactagtt ttcacgtttt ttcttgactc tttttttgct tgtgatataa
     6421 ttaactggta aacaaaatgt caaagaatag tatttttctc ttaaaaaaga gaagtctaaa
     6481 aggaaaggag tcagatatga gacagctagc aaaggatatc gatgcttttt tgaatgaggt
     6541 gattttgcag gcggaaaatc agcatgaaat cctaataggt cattgcacta gcgaggtggc
     6601 cctgaccaat actcaggagc atatccttat gctcttgtca gaggaatctt taacaaattc
     6661 agaattggcc cgtcgtctca atgtcagtca ggcggcagtt accaaggcca ttaagtcttt
     6721 ggtcaaggaa gggatgttgg aaacatctaa agattctaaa gatgcgcgtg tgatttttta
     6781 tcagttgact gacttggctc gtccaatcgc tgaggagcac caccatcacc atgagcatac
     6841 acttttaacc tatgaacaag tggcgactca gtttactcca aatgaacaaa aagtgattca
     6901 gcggtttttg actgctttag taggagaaat caaataatga gatatattac ggtagaggat
     6961 ttgtccttct attatgataa ggagcctgtt cttgaacata tcaattattg tgttgatagt
     7021 ggggaatttg ttaccttgac tggggaaaat ggagcggcta agacgacgct catcaaggct
     7081 agtcttggaa ttctgcaacc acgcattgga aaggtggcta tttcaaagac aaatacgcaa
     7141 ggtaagaaat tgagaatagc ctatcttcct caacaaattg ccagttttaa tgctggtttt
     7201 ccaagtacgg tctatgaatt tgtcaagtcg ggtcgctatc cgagaaaagg ctggttccgt
     7261 cgtttgaatg ctcatgatga ggagcatatc aaggctagtc tggactcagt tggcatgtgg
     7321 gaacatcgag acaaacgctt ggggtctcta tctgggggac aaaagcagcg agcggtgatt
     7381 gcgcgtatgt ttgcttctga ccctgatgtg tttatcctag acgagccgac aacggggatg
     7441 gatgcaggaa gtaaaaatga attttacgaa ctcatgcacc acagcgccca tcatcatggc
     7501 aaggctgttt tgatgattac ccatgaccct gaagaagtta aggattatgc ggatcgcaat
     7561 attcatctag tccgtaacca agactcgcca tggcgttgtt tcaatgttca tgagaatggc
     7621 caggaggtgg gccatgctta gtttattatc ttacgacttt atacaacgcg cctttttggc
     7681 ggttattgct atgagtcttt tctcaccggt attgggaacc ttcctcatct tgcgtcgtca
     7741 gagtttgatg agtgataccc ttagccacgt ctcactttca ggtgtagcct ttggtctggt
     7801 tttggggatt tctccaactg tttctactat tgccattgtc ttgattgcgg cggtctttct
     7861 ggagtatctc cgtacggttt acaagagctt tatggaaatc gggacagcta tcctcatgtc
     7921 aacaggtctg gctgtttctc tgattgtcat gagcaagggt aaaagctcga gttcaatgag
     7981 tttggaccaa tatctctttg gttcgatcgt gactatcagt gaagaacagg tcatttccct
     8041 ctttgtcatt gcggcggttg ttttgatttt gacctttctc tttcttcgtc ctatgtatat
     8101 cttaactttt gacgaagata cggcctttgt ggatggcttg ccagttcgta ccatgtccat
     8161 tctttttaac atggtgacag gggtggctat tgcccttatg attcctgcag caggagctct
     8221 tctggtatcg accattatgg tcttgccagc tagtattgcc ctgcgtctgg ggaaaaactt
     8281 taaatcggtt atgctgcttg ccagtgcgat tggctttttg ggaatggtag caggacttta
     8341 catttcctac tatgcagaaa cacctgcaag tgcaagtatt accattattt ttgtaactgt
     8401 ctttatacta atcagtttag taagacgttt tatcaaatag gagacgaacg tgaaaaaaat
     8461 tagcttatta ctagccagtc tatgtgcctt gtttttagtg gcttgttcca atcaaaaaca
     8521 ggcagatggt aaactcaata tcgtgacaac cttttaccct gtctatgaat ttaccaagca
     8581 agtcgcagga gatacggcta atgtagaact cctaatcggt gctgggacag aacctcatga
     8641 atacgaacca tctgccaagg cagttgccaa aatccaagat gcagatacct tcgtttatga
     8701 aaatgaaaac atggaaacat gggtacctaa attgctagat accttggata agaaaaaagt
     8761 gaaaaccatc aaggcgacag gcgatatgtt gctcttgcca ggtggcaagg aagaagaggg
     8821 agaccatgac catggagaag aaggtcatca ccatgagttt gacccccatg tttggttatc
     8881 accagttcgt gccattaaac tagtagagca catccgcgac agcttgtcag cagattatcc
     8941 tgataaaaaa gagacctttg agaagaatgc agctgcctat atcgaaaaat tgcaagcctt
     9001 ggataaggct tacgcagaag gcttgtctca agcaaaacaa aagagctttg tgactcaaca
     9061 cgcagccttt aactatcttg ccttggacta tggactcaaa caagtcgcaa tctcaggact
     9121 ttctccagat gcagagccat cagctgctcg cttggcagaa ttgacagagt atgtcaagaa
     9181 aaataaaatc gcctatatct attttgaaga aaatgcctca caagcccttg ctaacacact
     9241 ttcaaaagaa gcaggtgtca aaactgatgt cctcaatcct ttagaaagtc tgacagaaga
     9301 ggacaccaag gctggagaaa actacatttc cgtgatggag aaaaacctca aggctttgaa
     9361 acaaacaaca gaccaagaag gcccagcaat cgaacctgaa aaggcagagg ataccaagac
     9421 agtccaaaat ggttacttcg aggatgcagc tgtcaaggac cgcaccttga gtgactatgc
     9481 aggtaactgg caatcagttt atcctttcct tgaagacggc acgtttgacc aagtctttga
     9541 ctacaaggct aagttgactg gtaagatgac ccaggctgag tacaaggctt actatacaaa
     9601 aggctatcag acagatgtga ctaagattaa cattactgat aatactatgg aatttgttca
     9661 aggtggacaa agcaagaaat acacttacaa gtatgtcggt aagaaaattt tgacttacaa
     9721 gaaaggcaat cgtggcgtgc gtttcctctt tgaagccaca gatgctgacg ctggacaatt
     9781 caagtatgtt cagtttagtg accacaatgt tgccccagtt aaggcagaac atttccatat
     9841 cttctttgga ggcacaagcc aagaagccct ctttgaagaa atggacaact ggccaaccta
     9901 ctacccagat aacctatctg gccaagaaat cgcccaagaa atgttggcgc attgatgaga
     9961 aatcgactag ttcataagag ctagtcggtt ttttgatact agatggctaa cttcattata
    10021 gacctttcag aactttaaac aataaataaa actcttgaaa tatctgggct tatatgctag
    10081 aatgtagtta gtgtataagg ttcattagaa caccaaagcc cctaactagt gccatagtta
    10141 agggcttttt tgacgtatct tagcgattta acgggtgttt ataggctagt cagtcggtct
    10201 acttcttacc atctagccat ttgcagacga aatacaagat aattccagct ataacatctg
    10261 ctataatagt aagagcaagc tctggtataa ggctcattag tttcacctcc tctcacgaac
    10321 ccataggaac gtaatcggta accgatgaca aaagtattat atcacactaa atttagatca
    10381 tcaacctcac ttaatgcttg aactattgta gattatatgc taaaatgtag ttaattgata
    10441 aggttcatta gaacaccaaa gcccctaact atggccgtag ttaagggctt ttttgacgta
    10501 tcttagcgat ttaacgggtg tttataggct agtcactcgg tctacttctt actatctagc
    10561 catctgcaga cgaaatacaa gataattcca gctataacat ccgctataat agtaagagcg
    10621 agctctatga taaggctcat tagtttcacc tcctctcacg aacccatagg aacgtaatcg
    10681 gtaaccgatg acaaaaatag tataccacaa tacatttaga tcatcaaggt cacttaattc
    10741 ttgaaatata gggtctaggc gacaaagtct ttaaaatcag aaaaacgcat aatatcaggt
    10801 gtgcaaaaac ttgatactat gcgttttatt gtgggaaggt ttactccatt ttctcctgaa
    10861 attgagtttt tgtccagcct ctgtttttag ggttgctgag aaaataatgt catgtggtga
    10921 atatttgtaa atcagtcagc agacagaacg aatactcttc gaaaatctct tcacatcatg
    10981 tcagcttcgt ctttccgtat atatgtgact gacttcatca gttctatcta caacctcaaa
    11041 acagtgtttc gagctgactt catcagtttt caaatctgta ctttgagcaa gctgagacta
    11101 gcttcctatt tgattttcat tgaatatcag aaacccattc tccatcaaat aattcgactg
    11161 cgtctaataa tttttgatct ggcacggtgt ctgaaataaa ggttgtgtat ttggagaggg
    11221 gattaatttt aaaaaatcca gtcttgtaaa atttagaact atcaatcagt aagatggttt
    11281 catgggcttt gtcaataata ttcttttttg aaatagcttg gctgagagaa gcttcataaa
    11341 catattggtc atcaatacct cttgctgaac aaaatgctaa atcgatatta aaatgatcta
    11401 ataaagaatt ttccttatca tagttgacca cggaacagga ttgatgtttg acctcgccag
    11461 atgtgataaa gattttggag ctatctttaa cagtttcaga tagggtttgt gcagtatgta
    11521 aaccatttgt aaaaataatc aaattatcaa gttcagaaag atagggacaa agttcgtaga
    11581 cagtagtact ggaatccaga taaacacaca taccagaccg aataaagtct ttagcgagac
    11641 tagcgattag tcttttttgc ctagtacttt ctccttcccg tatttgatga gaaagttcaa
    11701 ttgtgttcat agaggacagg gtcacgtatc cgtgctttct tttgataaga ccttgatttt
    11761 ctaagaaaat taaatcacga cgtaaggtac ttgtgctgga gaaagtgatt tctgccagct
    11821 cttttacggc aattcttttt ttctttttaa taatttcaat caattcaagt acacgttcat
    11881 cttttatcat aagctcctcc taatttatca tttcaactat attatagcac aaattggagg
    11941 aatttgaatt atttttatga atattgggtt aacatttgaa cattattcaa gtaagcgttc
    12001 acatattgaa aaaataaaac gtggggatta taataaagtt aatcaaggac gaagagagaa
    12061 gaaaaatgga agcggtttta gcaatagatt taggtgcgac ttctggaaga gcaatcgttg
    12121 gttacctttc tgaaaataaa ctagtaatgg aagaaataaa tcgcttttct aatctaccta
    12181 ttagagtaaa agggcattta tcttgggata ttgactttct actagctaaa attcttgaaa
    12241 gtatccgctt ggctaatact agttacaaga ttttatctat cggtattgac acatggggag
    12301 ttgattttgg actgattgat aatgaaggta agctgttatt acaacctgtt cattatcgtg
    12361 atgaaagaac aaagggagtg ttaaaggaaa tatctgaaat gactgaatta gaaaaactgt
    12421 attcagagac aggaaatcag attatggaga taaatacctt gtttcaactc tttaaggcac
    12481 gtcaagaatc tcctgactct ttctataaga ccaataagat tcttttaatg ccagatttgt
    12541 ttaattatct cttgacaggt aagtttgcta cagaaaaaag cattgcttca acaactcaat
    12601 tatttgatcc taggagtcaa aactggaatc agaatatctt aaaactattt gaattggatt
    12661 catctttact tcctgagatt gtttcagagg gaaatgttct tggaaggata aaaaaggagt
    12721 atggtttagg cgatattcct gttgtgaatg tttgtagtca tgatacagca agcgcgattg
    12781 tctcagtacc taagacagaa ggtagtttat ttatttcatc aggtacttgg tctttggttg
    12841 gagtggaact tacttcaccg cttcttacta ccgaatcctt cagttatgga tttacaaatg
    12901 aagtcggtaa agatggagtg attacatttc tgaagaattg tacagggttg tggatcatag
    12961 aggaactaag acgttcattt gaacgaagag ggaaagccta ttcttttgat gatattagga
    13021 caatggtgga gaaagaaaaa gaaaatcttc ctctgattga tactgaatca actgaatttg
    13081 caacagaatc tgatatgcac aagactttga cagaatatct agcttatcat catgaaacta
    13141 gagagtggac agatggacaa ctatttaaga ttgtttatga aagcctagct gaaacgtata
    13201 ggaaagcgat agagttacta gaagaactaa ctcataaggt ttataagagg atatatgtga
    13261 ttggaggagg tgctagagcc agttacttta accaaatgat tgctgataga actggtaaag
    13321 aggttcttac aggtttgact gaggctacag ctgtggggaa tattgttgtg cagctcatag
    13381 ctatgggaca attaaaaggg atggaagagg ctcaccatgt tattgaggag tttctacaat
    13441 tagagagtta ttactcccaa aagaattaaa aagattgaga gtttgtaaat ttgcctccct
    13501 cccccttctt agcttttgtg caggaagggg ggataattgg tgaattgaaa aatatttagt
    13561 gttttgatat gaggaggaca aggatgtcag atgtaaaaca agaattaatt aaatatggta
    13621 agaagctagt agaaacagat ttgacgaaag gaacaggtgg gaatctcagc gttttcgatc
    13681 gtgaaaaaca attgatggca attaccccgt cgggtattga tttctttgaa atcaaagaat
    13741 ccgatattgt agtgatggat attaatggaa atgttgtaga gggagaacgc ttgccatcta
    13801 gcgaatggta tatgcatttg attcaatatc aaactcgtga tgatatcgat gcaattatcc
    13861 atgctcatac aacttatgca acagtattag cttgtctcag agaaccactt ccagcgagtc
    13921 attatatgat tgcagtggca gggaaagatg ttcgggtagc tgagtatgca acatatggca
    13981 cgaaagaatt ggctgtgaat gcagctaaag caatggaagg tcgtagagca gttttactag
    14041 cgaatcatgg aattttagca ggtgcacaaa atttattgaa tgcatttaat attgttgaag
    14101 aagttgaata ttgtgcaaaa atttattgtt tagctaagaa ttttggagag ccagtagttc
    14161 ttcctgatga ggagatggaa ttgatggcag aaaaatttaa aacatacggt cagagaaaat
    14221 agggaggata ttaatgttaa aacatatacc gaaaaatatt tctccagatt tattgaagac
    14281 tttaatggaa atgggacatg gagatgaaat agtattagct gacgcgaatt atccttctgc
    14341 ctcatgtgca aataagctaa ttcgttgtga tggtgtaaat attccagaat tattagattc
    14401 cattctgtat ttaatgccat tagatagtta cgtcgatagt tcaattcagt ttatgaacgt
    14461 tgtttcgggt gatgatattc ctaagatatg gggtacctat agacagatga ttgaaggtca
    14521 tggtacagat cttaaaacga ttacttatct tagaagagaa gacttttatg aacgtagtaa
    14581 gaaagcttat gctattgttg ctacaggaga aacttcactt tatgctaata ttatccttaa
    14641 gaaaggagta gttgttgaaa gagaaaatgt ttaatagagg aattttagtt gccagtcatg
    14701 gtaattttgc tagcggagct ctcatgaccg cagaaatgtt tgttggtgag acaacaaatg
    14761 atagagttag gacattaggt ttgatgcctg gagagaatat tgtagagttt gaacattatt
    14821 ttaaaaatca agtaaatgaa ctgttagact caaatcaaga ggttatcgtt ttgactgact
    14881 tgattggagg aagtcctaat aatgtggctt tgtcacggtt tttaaatttg gattcagttg
    14941 atattgtaac agggtttaat atccctctcc tagtggaatt aatatcaagt tatgattcaa
    15001 aaatcaattt agaagaaatt gttcaaaatg ctcaaaatag tttgtttaat gttaaacaac
    15061 aacttaacgt agaggaggaa gaggatttat gtctatagag tttgttcgta ttgatgaccg
    15121 tctggtacat ggtcaagttg tcactacgtg gctaaaaaag tatgatattg agcaagttat
    15181 cattgttaat gatcgcatct cagaagataa aacacgacaa tctattttaa agatttctgc
    15241 accggtaggt ttaaaaattg ttttctttag tgtaaaacgg tttgtggaag ttttaaactc
    15301 tgtgccaata aaaaagagaa caatgctgat atatacaaat ccaaaagatg tgtatgattc
    15361 tattgaagga aatttaaaat tggagtacct caatgtagga cagatgagta aaacggagga
    15421 aaatgaaaag gtaacgggag gtgtagctct aggtgaagaa gacaaatatt attttaagaa
    15481 aatagttgat aagggaacga gagttgaaat tcaaatggtt cctaatgata aagttacaat
    15541 gttggaaaaa tttttataaa aataatttaa ggaggtacag tatatgctat tcacacaagc
    15601 attactggtg acattagttg ggattattgc cactattgac tataatggac cgttatttat
    15661 gattcaccgt cccttagtta caagtgcaat ggttggctta gtcttaggag atttcaccca
    15721 aggtgttctt attggttcag ctcttgaatt aacttggctc ggtgtaacag gtattggagg
    15781 ttacactcca ccagatacta tttcaggtgc gattattggt actgcatttg gtattttatc
    15841 tggtcaagga gaaactgctg gtatcgctat agcagttcca attgcagttg ctacccaaca
    15901 gttggatgtt cttgcaaaaa ctttagatgt ttattttgtg aaaaaagctg ataatgatgc
    15961 taaaaacgga gattattcaa agatcggttt ttatcattat tcaagtttgg ttttaatcac
    16021 gttatttaaa attgtaccaa ttttcctagc tattatgctt ggaggggaat atgtggcaga
    16081 cttgtttgct aaggttccac caatcgttat gcagggactt aactctgcag gtgctttact
    16141 accttcaatt ggttttggta tgcttttaaa tatgatgctc aagaaaaata tgtgggtatt
    16201 cttgttgatt ggattcattt gttctgtgta tggaggaatg tcaaccattg ggatctcact
    16261 agttggtatt gcggtagcat acttctacga tatgattgga agtaaaccac aagaaacaac
    16321 ttcaagtagt gatgttgagg aggatcttga tctatgatga ataataaagt aactaaagtt
    16381 gaacttaaaa aagttttcaa acgaagtttt atgtatggtt cttcatggaa ctatgagaga
    16441 atgcagaacc taggttttct atatacaatt cttccagtat tgaaaaaact atacccagac
    16501 aaagattcag cttctcctgc aatgaaacgt caccttgagt ttttcaatac tcatcaaaca
    16561 gcggcaccat ttattcttgg agttacttcc gctatggaag aacaagaagg aaatgaaggt
    16621 gcagcttcaa ttactggtat taaagttggc ttgatggggc cactggctgg tctaggagat
    16681 agtttgttct ggctgacact agttcctatc tgttttagta ttggtgcgtc ttattctaaa
    16741 gacggcggtg ctttaggtat ctttatcgcc ttaatattgt ttaatattat taatattcct
    16801 gttaaatatt tcggtttgaa atatgggtat actaagggtt ctagtcttat ccaagaaaat
    16861 aatacaaaag gaacattgaa tcgcgttacg agtatggcga cagcattagg gctagtacta
    16921 gtgggtggtt tgattccatc aatggttggt attaattttg gattagaatt taagcagggg
    16981 gaacttgtta tttctgttca agaaatgatt acaaaattaa ttccaggatt tatccctatg
    17041 gctttgactt tattaatgtg taaattaatt agaaaaggaa agaatccggt tgtactaatc
    17101 tttagtgtta tggctattgg agttatccta gttgttttag gaattttgaa gtagtagaaa
    17161 gtgtggaggt ggtatttggg atatcacctc cattttggaa gagaggtaaa gagtgaaatt
    17221 atggtataag aaagctgccg caaattggaa tgaagccttg ccgattggga acggtcattt
    17281 aggtggtatg atttatggtt cagctacaaa agaatgtatt caactaaacg atgagactat
    17341 ttggtataga ggaaagtcag atagaaataa tccagactca ctattgcatc ttaaaaaaat
    17401 tcgggaatat cttttagatg gagaaattca gaaagccgaa gaattgataa agttaacaat
    17461 gtttgctacc ccaagagatc aaagccacta tgaattactt ggggaacttt acattgagca
    17521 tatagatatt cagtcttgtg ctctttcatt gtatgaaaga gagctagatt tagatacagc
    17581 tatttctaat gttgtgtttg agcctaatag ttgtaattta caaataaaaa gagaatattt
    17641 tacgagtttt aataagaata ttttatgttg ccgtatagtg tcatcagttc aaaacacatt
    17701 aaatttaaac attaatttgg gtagaaataa acggtttaat gacgaagtat ctaaactgga
    17761 ttcaagtaca attttaatgt cggcctctgc tggaggtaga aaaggtgttc agtttaaagt
    17821 agtatgtcat tctaaggtta cggatggtga agtaagtgta ttgggagaga caatagttat
    17881 tcggaatgct acagaggtat ttctttatct caaatcaatg acggattatt ggggaaatat
    17941 agatatttct tctcttcagg gagaatttag tagtattgat tactttacag aaaaagatga
    18001 acatgtaaaa aaatatcagg agcaatttaa tagagttgat tttaaactag actatagtaa
    18061 aggttgtctt agcattccaa cgaatctact tcttgaaaac actaaaaagt atagtaacta
    18121 cttgactaac ttgttatttc attatggaag atatctgtta atatcgtcta gtcaaccgaa
    18181 tggtttacct gccaatcttc aaggaatatg gtgtgatgaa ttaaatccaa tttggggttc
    18241 taaatatacg attaatatta atactcaaat gaattattgg atggtaggtc catgtgattt
    18301 accagaagta gaatatccat tatttgatat gctcgaaaga atgagagaac cgggaagact
    18361 aaccgctaag aaaatgtatg gagctagagg ttttacagca catcataata cggatggttt
    18421 tggcgatacg gctccccaat ctcatgccat gggggctgca atttgggtat taactattcc
    18481 atggttatgt actcatattt gggaacacta tttatatttc caagatgagc gtattcttac
    18541 ggaacatttt gaaatgataa aagaagcatt tcttttcttt gaagattatt tatttgaggt
    18601 ggatggctac ttgatgacag gtccaagtgt ctcaccggaa aataaatatc gcttaaaaaa
    18661 tggtattgaa ggaaatgctt gtctatcatc tacaattgat aatcaaattt taagatattt
    18721 ttgtgattca tgcattggaa ttgcaaaaca attaggagac aattcggatt ttattagtcg
    18781 tgtgaaggag ttaaaaaaga aactacctaa aacaaaaata ggtagtaatg ggcaaatcca
    18841 agaatggtta gaagattatg aagaagtaga gcctgggcat agacacattt cacctctatt
    18901 tgggctttat ccttataatg agattgatat tcataaaact ccggaattag cagaagcagc
    18961 taaaatcact atcaatagga gattatcaaa cgctaacttt ttatcttcac aggagaggga
    19021 gcaagcgatt aataattggt tagtaagtgg tttgcatgct agtacacaaa caggttggag
    19081 tgctgcatgg ctgattcatt tttttgcgag actatatcaa ggtgaacctg cttataacca
    19141 gattaatggt ttgttaaata atgcgactct tggcaattta tttcttgacc atccaccatt
    19201 tcaaattgat ggtaatttag gtttggtgag tggaatttgt gaattattag tacagagcca
    19261 tcataattgg ttatcactaa ttccagcttt accttctgct tggtcagaag gagaagtgaa
    19321 aggtttcaga gtaagaggag gatataaggt atcgtttgct tggaaaaatg gggatataac
    19381 attcctaaaa ttggaaggag gaaacaaaga tcaaaaagta agagtaagaa tatatggcaa
    19441 aaatactgat gtacaaaata ttgaattggt atttaattca gaaaaaatta ttgagttaaa
    19501 tttttaggta taagtcatga ataaagaaaa aataaaaaga aaattaatca caatactgtt
    19561 tgtatgtatt gggatgttat gttttggatt gttagcagga gttaaggctg ataatcgtgt
    19621 tcaaatgaga acgacgatta ataatgaatc gccattgttg ctttctccgt tgtatggcaa
    19681 tgataatggt aacggattat ggtgggggaa cacattgaag ggagcatggg aagctattcc
    19741 tgaagatgta aaaccatatg cagcgattga acttcatcct gcaaaagtct gtaaaccaac
    19801 aagttgtatt ccacgagata cgaaagaatt gagagaatgg tatgtcaaga tgttggagga
    19861 agctcaaagt ctaaacattc cagttttctt ggttattatg tcggctggag agcgtaatac
    19921 agttcctcca gagtggttag atgaacaatt ccaaaagtat agtgtgttaa aaggtgtttt
    19981 aaatattgag aattattgga tttacaataa ccagttagct ccgcatagtg ctaaatattt
    20041 ggaagtttgt gccaaatatg gagcgcattt tatctggcat gatcatgaaa aatggttctg
    20101 ggaaactatt atgaatgatc cgacattctt tgaagcgagt caaaaatatc ataaaaattt
    20161 ggtgttggca actaaaaata cgccaataag agatgatgcg ggtacagatt ctatcgttag
    20221 tggattttgg ttgagtggct tatgtgataa ctggggctca tcaacagata catggaaatg
    20281 gtgggaaaaa cattatacaa acacatttga aactggaaga gctagggata tgagatccta
    20341 tgcatcggaa ccagaatcaa tgattgctat ggaaatgatg aatgtatata ctgggggagg
    20401 cacagtttat aattttgaat gtgccgcgta tacatttatg acaaatgatg taccaactcc
    20461 agcatttact aaaggtatta ttcctttctt tagacatgct atacaaaatc cagctccaag
    20521 taaggaagaa gttgtaaata gaacaaaagc tgtattttgg aatggagaag gtaggattag
    20581 ttcattaaac ggattttatc aaggacttta ttcgaatgat gaaacaatgc ctttatataa
    20641 taatgggaga tatcatattc ttcctgtaat acatgagaaa attgataagg aaaagatttc
    20701 atctatattc cctaatgcaa aaattttgac taaaaatagt gaggaattgt ctagtaaagt
    20761 caactattta aactcgcttt atccaaaact ttatgaagga gatgggtatg ctcagcgtgt
    20821 aggtaattcc tggtatattt ataatagtaa tgctaatatc aataaaaatc agcaagtaat
    20881 gttgcctatg tatactaata atacaaagtc gttatcgtta gatttgacgc cacatactta
    20941 cgctgttgtt aaagaaaatc caaataattt acatatttta ttgaacaatt acaggacaga
    21001 taagacagct atgtgggcat tatcaggaaa ttttgatgca tcaaaaagtt ggaagaaaga
    21061 agaattagag ttagcgaact ggataagcaa aaattattcc atcaatcctg tagataatga
    21121 ctttaggaca acaacactta cattaaaagg gcatactggt cataaacctc agataaatat
    21181 aagtggcgat aaaaatcatt atacttatac agaaaattgg gatgagaata cccatgttta
    21241 taccattacg gttaatcata atggaatggt agagatgtct ataaatactg aagggacagg
    21301 cccagtccct ttcccaacac cagataaatt taatgatggt aatttgaata tagcatatgc
    21361 aaaaccaaca acacaaagtt ctgtagatta caatggagac cctaatagag ctgtggatgg
    21421 taacagaaat ggtaatttta actctggttc ggtaacacac actagggcag ataatccctc
    21481 ttggtgggaa gtcgatttga aaaaaatgga taaagttggg cttgttaaaa tttataatcg
    21541 cacagatgct gagactcaac gtctatctaa ttttgatgtg attctatatg acaataatag
    21601 aaacgaagtt gctaagaaac atgttaataa tttgtcgggt gaatctgtta gtctagattt
    21661 caaagaaaaa ggagcaaggt atattaaagt taaattacta acgagtggag tgcctttgag
    21721 tttagcagaa gtagaggttt ttagagaatc agatggtaag caatctgaag aggatataga
    21781 taaaataaca gaagataaag tagtctctac aaataaggta gctactcaaa gttcaaccaa
    21841 ttatgagggt gtagctgctt tagcagttga tggtaataaa gatggagatt acggacatca
    21901 ttcggtgact catactaagg cagattctaa cgcttggtgg caggtcgatc tgggagaaga
    21961 gtttacggtt tctaaagttg atatttataa tagaacagat gccgaacctc agcgtttatc
    22021 taattttgat gttatttttc tatcttcatc aggagaagaa gtttttagaa gacattttga
    22081 taaagtagtt gatggtttgt tatctttaaa agtaccttct gtaggggcta agctagtcaa
    22141 aatagaatta aaatcagcag ctattccgtt aagtttagcg gaagttgaag tctatggttc
    22201 aaagagaact ccgaagaaac tttctaatat tgcattaacc aaagaaactc gacagagttc
    22261 aacggattac aatggttttt ctcgtctagc agttgatgga aataaaaacg gagattatgg
    22321 tcatcattca gtgactcata ccaaaggaga ttctccttca tggtgggaga tagatttagc
    22381 acaaaccgaa gaattagaaa agttaattat ttataataga acagatgctg aaattcagag
    22441 attatcaaat tttgatatta ttatatatga ttcaaataat catgaagttt ttaaacaaca
    22501 tattgacagt ttagaaagca ataatctatc catagactta aaagggctga agggaaaaaa
    22561 ggttagaatt tctttgagaa acgcaggaat tcctttaagt ttggcagagg tagaggttta
    22621 tacttataag taattttaaa aattatcatc ggtagtatga aagaaacaga aaaataagag
    22681 gaaaatagta tgattcaaca tccacgtatt gggattcgtc cgactattga tggtcgtcgt
    22741 caaggtgtac gcgaatcact tgaagtacaa acaatgaaca tggctaaaag tgtggcagat
    22801 ttgatttcaa gcacattgaa atatccagat ggggaacctg tggaatgcgt gatttctcca
    22861 tctactattg gccgtgtacc agaggctgca gcttcccatg agttgttcaa aaaatcaaat
    22921 gtttgcgcaa caattacagt tacaccatgc tggtgttatg gtagtgaaac tatggatatg
    22981 tctccagata ttcctcatgc tatttgggga tttaatggga cagaacgccc aggagctgtc
    23041 tatcttgcag ctgtactagc ttcacatact caaaaaggga ttccagcctt tgggatttat
    23101 ggtagagatg ttcaggaagc taatgataca gctattccag aagatgtcaa agaaaaactt
    23161 ttacgttatg cgcgggcagc tcttgcaact ggcttgatga gagacactgc ttacctatca
    23221 atgggtagtg tttcgatggg gattggtggt tctattgtaa atccggattt cttccaagaa
    23281 tacttaggaa tgcgaaatga atcggtagat atgacggagt tcacacgccg tatggaccgt
    23341 ggtatttacg accctgaaga gttcgaacgt gcgctcaaat gggtgaaaga aaacgtaaaa
    23401 gaaggattcg accataaccg tgaagacctt gttttaagcc gtgaagaaaa agatagacaa
    23461 tgggaatttg ttattaagat gttcatgatt ggacgtgact taatggttgg taacccaaga
    23521 cttgctgaac ttggttttga ggaagaagca gttggtcacc atgctttagt agctggtttc
    23581 caaggtcaac gtcagtggac agaccatttt ccaaatggag attttatgga aactttcctc
    23641 aatactcagt ttgactggaa tggtattcga aaaccatttg tatttgcgac agagaatgat
    23701 tcactaaatg gtgtgtctat gctctttaat tatctattaa caaatactcc acaaatcttt
    23761 gctgatgtgc gtacttattg gagtccagag gctgttgaac gtgtaacagg atatacttta
    23821 gagggtcgtg ctgcagctgg cttcttacat ctaatcaact ctggttcttg tacattagat
    23881 ggtacaggtc aagctactcg agatggcaaa cctgttatga aaccattctg ggagttggat
    23941 gaaagtgaag tgcaggctat gcttgaaaat acagacttcc caccagcaaa ccgcgaatac
    24001 ttccgtggag gaggattctc aactcgtttc ttgacgaagg gggatatgcc agtaacaatg
    24061 gtacgtctca atcttctaaa aggggttggt ccagtgctac aaattgcaga aggttataca
    24121 cttgaacttc ctgaagatgt tcaccatact ttagataatc gtacagatcc aggatggcca
    24181 actacttggt ttgctccacg tttgacagga aaaggtgctt tcaagtctgt ctatgacgtc
    24241 atgaataatt ggggagctaa tcacggagcc ataacatatg gacacattgg agcagacttg
    24301 attaccttgg cttctatgtt gagaattcct gtcaatatgc ataatgtacc tgaggaagat
    24361 atctttagac ctaaaaattg gtccttattt ggaacagaag atctagaatc agcagactat
    24421 cgtgcatgtc agttgttggg accactacat aaataaaact tgtttatata ggaggtgaac
    24481 ttacgtccct cctatccttt taaaaagatt tgttaaacaa ttcacaaata attgaaaacg
    24541 aatacaaaaa gtaatataat gatgttaaat agatagcgcg gaggcgcagg aggaaaatta
    24601 tatggctaca ttttatgttc cggcagtcaa ccttattgga aaaggtgttg taaatgaagt
    24661 gggtccttat atcaaggaac ttggctataa aaaggcactt ttggtgacag ataagtacat
    24721 cgaaggcagt gatattttac ctaagacttt aaaaccactg gatacagaag gaatcgaata
    24781 tgtcatcttt agcgatgtag agccaaaccc tacttgtaag aatgtcacag atggggtagc
    24841 tgctttgcaa gaacatggat gtgattttat catcagtctt ggcgggggtt ctccacagga
    24901 tgcagctagt tgtatttcta tcatggctac aaatggtgga aaaccacagg attatgaagg
    24961 gcttcataag tctgctaaaa aaggcttgcc agttgtggct atcaatacaa cggcaggaac
    25021 ttctgcagaa atcactatta actatgtgat tactgatgaa gaacgcaagg ttaagatggt
    25081 aatggttgac aagaatagcc ttgctcttat ctctgttaat gacccggaac tcatgctttc
    25141 caaacctaaa ggtctgactg ctgctactgg tatggatgct ctgactcacg ctgttgaagc
    25201 tttggtaaca cctggtgctt atgatgtaac caagaaactg tctattggtg ctattgagct
    25261 tatcaaggaa tatcttcctc gtgctgtaga aaatggacat gatattgaag cgcgtgaagg
    25321 tatggtcaat gccatcttcc ttggtggtat gagctttaat aatgctggtc ttggttatgt
    25381 tcactcaatg gctcaccaac tcggtgcagt atataatttg ccacatggtg tttgctgtgc
    25441 catgttgcta ccagttatag aacgtgaaaa tgctaaacgt gtaccagaag ctttccgcaa
    25501 tgttgccaaa gccttgggcc ttcatgtgga aggtaaatca gatcaagagt gtgccgatta
    25561 tgcgattgct gagattgaga agctttctga gacagtaggt attcctaaga aattgactga
    25621 acttggtatt gaagaaaaag atttcgactt tgaatacctt tctaagaatg ccttgattga
    25681 tgcctgcgca ccaggaaatc catttatgcc aaccttagaa gaaacgattg ccttttataa
    25741 agagttattt tagcaagaga ttagacgaca ataggacaat tcacctctaa ttattgacat
    25801 ttcaggaaaa atcgcagtaa aaacggcaca gccttcttta aatgtgctat aatactagaa
    25861 aaatacttgt ggaggttcca ttatggcaat atttttcatg atttttctga ttgtttgtgt
    25921 gctcctattg gtgatagtca cactgagtac agtttatgtg gttcgtcagc agtcggtggc
    25981 gattattgaa cgctttggga aataccaaaa ggttgctaat agcggtattc atattcgctt
    26041 gccttttggg attgactcga ttgcagcacg gattcagttg cgcttgttgc aaagtgatat
    26101 tgtggttgag actaagacca aggacaatgt gttcgttatg atgaatgtag cgactcagta
    26161 ccgtgtcaac gagcagagcg tgacagatgc ttactataaa ctcatacgtc cagaatctca
    26221 gattaaatct tatatcgaag atgctcttcg ctcttctgtt ccaaaattaa ccttggatga
    26281 attgtttgag aaaaaagatg agattgccct tgaggttcaa caccaagtag cagaagaaat
    26341 gaccacttac ggctacatta tcgtgaaaac cttgattacc aaggtcgaac cagatgcaga
    26401 agttaagcaa tctatgaatg aaatcaatgc ggcgcaacgt aagcgggtcg cagcacaaga
    26461 attggcggaa gctgacaaga ttaaaattgt cactgcagct gaagccgaag cagaaaaaga
    26521 ccgccttcat ggtgtgggga ttgcccaaca acgtaaggcg attgtggatg gattggcaga
    26581 gtctatcacc gaactcaagg aagccaatgt tggcatgaca gaagaacaaa tcatgtctat
    26641 cctcttgacc aaccagtatt tggatacctt gaataccttt gcctctaaag gaaatcaaac
    26701 catcttttta ccaaatactc caaatggtgt ggatgatatc cgtacacaaa tcttgtcagc
    26761 ccttcgcgct gagaagaaat aatagactaa tactcttcga aaatctcttc aaactacgtc
    26821 agcgtcgtct tgccgtatag atgttactga cttcgtcagt tctatctgca acctcaaaac
    26881 agtgttttga gctgacttcg tcagtcttat ctactacctc aaaacggtgt tttgagcaac
    26941 ctgtggctag tttcctagtt tgctctttga ttttcattga gtataaagag cttggcaaca
    27001 ggctcttttt gtattgcgtt tattaagaaa aacaaaaaac atcgatatac atttaactaa
    27061 aaattattgt atgttatctc ccttaattag gaatgataag ggaataacta gaaagatttg
    27121 tgaatacaaa ctatttctga tatacaaaat atacagtaat aatgaatgat gggagatggg
    27181 atgaaagaat ttcaatttga gagaaagcag cgtttttctt tgaggaaata tgcaatagga
    27241 gcttgttcgg tcttgctagg aacgagttta tttttttgct ggtatgggtg ctcagcctgt
    27301 acaggataca gaaacgagtt cagcactaat ttcaagtcat tatttggatg agcaggattt
    27361 atctgaaaag ctgaaatctg agttgcaatg gtttgaatta gaaaacaagc ttttgaactt
    27421 atgggagcat taggttacta tgaaggattt gttccttatg tttcaaatca atacaaaaac
    27481 caagctgaag aagaaggcaa accgctatct gataaatata ttttcgaaaa aatcttagga
    27541 aaaacatatg cagccttcaa aaaagatcaa atttctgagc gtgtcgagaa attaggtaag
    27601 ttaaaaccta ttacaataaa ttacaacgga aaatcagaag taattgatag taaagaaaaa
    27661 ttacaagagc ttatgaataa agccgttaaa gacgaagtgg ctcaaatata gtaaaatgaa
    27721 ataagaacag gacaaatcga tcaggacagt caaatcgatt tctaaaaatg ttttagaagt
    27781 agaggtgtac tattctagtt tcaatatact ataaaatcag gcaataccac ggctaaaaag
    27841 tttgagttta tcgaaacacc agtgcaaaaa ctgaaaaaag cgatttataa agctcatctc
    27901 aaagattcag atgactttag accagaaaca tccac
//
LOCUS       DAVBOU010000027        27612 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBOU010000027 DAVBOU010000000
VERSION     DAVBOU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27612
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.027"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(101..642)
                     /locus_tag="VQ879_001246"
                     /pseudo
     CDS             complement(101..642)
                     /locus_tag="VQ879_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(718..1494)
                     /locus_tag="VQ879_001247"
                     /pseudo
     CDS             complement(718..1494)
                     /locus_tag="VQ879_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1418..1612)
                     /locus_tag="VQ879_001248"
     CDS             complement(1418..1612)
                     /locus_tag="VQ879_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143400.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
     gene            complement(1782..2132)
                     /gene="tnpB"
                     /locus_tag="VQ879_001249"
                     /pseudo
     CDS             complement(1782..2132)
                     /gene="tnpB"
                     /locus_tag="VQ879_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(2113..2298)
                     /locus_tag="VQ879_001250"
     CDS             complement(2113..2298)
                     /locus_tag="VQ879_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143401.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(2602..4164)
                     /gene="guaA"
                     /locus_tag="VQ879_001251"
     CDS             complement(2602..4164)
                     /gene="guaA"
                     /locus_tag="VQ879_001251"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3143402.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4306..5004
                     /locus_tag="VQ879_001252"
     CDS             4306..5004
                     /locus_tag="VQ879_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3143403.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5047..5943)
                     /locus_tag="VQ879_001253"
     CDS             complement(5047..5943)
                     /locus_tag="VQ879_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3143404.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5952..6887)
                     /locus_tag="VQ879_001254"
     CDS             complement(5952..6887)
                     /locus_tag="VQ879_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3143405.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6884..7609)
                     /locus_tag="VQ879_001255"
     CDS             complement(6884..7609)
                     /locus_tag="VQ879_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3143406.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(7693..8328)
                     /locus_tag="VQ879_001256"
     CDS             complement(7693..8328)
                     /locus_tag="VQ879_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3143407.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8330..9157)
                     /locus_tag="VQ879_001257"
     CDS             complement(8330..9157)
                     /locus_tag="VQ879_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3143408.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9179..9514)
                     /locus_tag="VQ879_001258"
     CDS             complement(9179..9514)
                     /locus_tag="VQ879_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3143409.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(9515..10046)
                     /locus_tag="VQ879_001259"
                     /pseudo
     CDS             complement(9515..10046)
                     /locus_tag="VQ879_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10677..11288
                     /locus_tag="VQ879_001260"
     CDS             10677..11288
                     /locus_tag="VQ879_001260"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3143410.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11333..12061
                     /gene="rlmB"
                     /locus_tag="VQ879_001261"
     CDS             11333..12061
                     /gene="rlmB"
                     /locus_tag="VQ879_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3143411.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(12100..13011)
                     /gene="trxB"
                     /locus_tag="VQ879_001262"
     CDS             complement(12100..13011)
                     /gene="trxB"
                     /locus_tag="VQ879_001262"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3143412.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13077..13301)
                     /locus_tag="VQ879_001263"
     CDS             complement(13077..13301)
                     /locus_tag="VQ879_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3143413.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13379..14122)
                     /locus_tag="VQ879_001264"
     CDS             complement(13379..14122)
                     /locus_tag="VQ879_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3143414.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRRALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(14122..14922)
                     /locus_tag="VQ879_001265"
     CDS             complement(14122..14922)
                     /locus_tag="VQ879_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3143415.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15080..15436)
                     /locus_tag="VQ879_001266"
     CDS             complement(15080..15436)
                     /locus_tag="VQ879_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3143416.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15449..15961)
                     /locus_tag="VQ879_001267"
     CDS             complement(15449..15961)
                     /locus_tag="VQ879_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3143417.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15961..16455)
                     /locus_tag="VQ879_001268"
     CDS             complement(15961..16455)
                     /locus_tag="VQ879_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143418.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16590..17036
                     /locus_tag="VQ879_001269"
     CDS             16590..17036
                     /locus_tag="VQ879_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3143419.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17033..17680
                     /locus_tag="VQ879_001270"
     CDS             17033..17680
                     /locus_tag="VQ879_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3143420.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17701..18282)
                     /gene="pdxT"
                     /locus_tag="VQ879_001271"
     CDS             complement(17701..18282)
                     /gene="pdxT"
                     /locus_tag="VQ879_001271"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3143421.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18283..19158)
                     /gene="pdxS"
                     /locus_tag="VQ879_001272"
     CDS             complement(18283..19158)
                     /gene="pdxS"
                     /locus_tag="VQ879_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3143422.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19310..20689)
                     /locus_tag="VQ879_001273"
     CDS             complement(19310..20689)
                     /locus_tag="VQ879_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3143423.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20983..21906
                     /locus_tag="VQ879_001274"
     CDS             20983..21906
                     /locus_tag="VQ879_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3143424.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21966..22571
                     /locus_tag="VQ879_001275"
     CDS             21966..22571
                     /locus_tag="VQ879_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3143425.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22590..23834
                     /locus_tag="VQ879_001276"
     CDS             22590..23834
                     /locus_tag="VQ879_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3143426.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(24057..24314)
                     /locus_tag="VQ879_001277"
     CDS             complement(24057..24314)
                     /locus_tag="VQ879_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3143427.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24356..26392)
                     /locus_tag="VQ879_001278"
     CDS             complement(24356..26392)
                     /locus_tag="VQ879_001278"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3143428.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26652..27569)
                     /gene="glyQ"
                     /locus_tag="VQ879_001279"
     CDS             complement(26652..27569)
                     /gene="glyQ"
                     /locus_tag="VQ879_001279"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3143429.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         8150 a         6184 c         5033 g         8245 t
ORIGIN      
        1 tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt atagaaatat
       61 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
      121 tttccaacaa actcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
      181 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
      241 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
      301 ccgtctttta aaatggtctt aaaggtttct ttatacttga ggctgtattc aattgccctt
      361 cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa gtcttccatt
      421 aggggctgga cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa
      481 ggcaaataac tggtcacgat aggctaaacc tttagctcct aaggatgatt tatctgcttg
      541 cttgggggtc gcttcaaaaa atttccttct cacatgcgcc caacatccaa caagttcagc
      601 ttcttccagt tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
      661 gctcctaaac cttagactgc tatcgcatag gcagaactag aggactaaag ttctaagtta
      721 ctgccgcaac atatcacaat gcatatagcc agaataattt cctaggaatt cttgcactac
      781 cgaaccactc cgacgctgat catggtggta cagcgtaatc ccttgtttct cagctttccc
      841 agacaaaaaa gtccaatagt aagtcagctg actatcactt tctaagaccc gataagaggt
      901 ttcatctgca tgaagaagag cttgttctaa caacttttct cgtaaaaggt tataaaggga
      961 ctctaaatag tattgactcg ccttgatatg ccaattagca atttccttac gtgtgattgg
     1021 taaacccatc ttagcccaat cttcttctta gcgataattg ggtaccttca gaataaactt
     1081 ctgatggatg gtgtgagcga taatagaagc tgagccaagg ctatgcgcca aaggggcttt
     1141 aggaatagga gctttcacga ttttatcact tggattattc ttactgcatg tttggcattt
     1201 gtaagcgtgt tggatatgat tcactctttt taattgcgca agaataaaga ccaattcttg
     1261 tcgttgaagg ctcgctccaa tctcttttag ctctccctga cagtcagggc aaatgcagtt
     1321 ctctaagcga tgatgaactt cttctgaatc aaattgggca agaatagctt gacgtttccc
     1381 tttagctttc ttacgtttat aggtgatttc ttctctttca actgggtaag tcagagtctt
     1441 cttccatatt ttgttcctct tcaaaaagac tgagttgtcc agatgggcaa acacttttct
     1501 cagaggattt tccatagagc ttttgcgtta gataagccac ttgttcacga agaagggcaa
     1561 gttcattggt gagactatca attgtagcac tctgttgttg aatgattttc aatcttctcc
     1621 catagacttt cctccttatt tcctaacttt attatatagt gtattgaatc tataacagta
     1681 caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcat
     1741 atcttatttc aattcactat actaaaaaga aagtcctcat ttcaatagaa atcacgactt
     1801 tctgatgaat ttatttttgg agtgatagaa aagcccttca taagccagtc tacttgttca
     1861 ggtgtgagag ctttgacatc cttttctgta ctgggtcaag tcagtctgcc gttctcaaag
     1921 cgtttatata gtagccaaaa tccttgacca tcccagtaaa gggctttaaa gcggtcttta
     1981 cgtccaccac aaaagagaaa aacttgaccg gagaaaggat ctaattcaaa gtgggtttta
     2041 accagataag ccagtgaatc aatgccttgc ctcatatccg ttttcccaca tacgagatag
     2101 acctgcccta ggctagatag atgaattgtc atagagcaac accttatcca aaagctgttc
     2161 taccatttcg agattgagag attgaaaaaa acttacttca agcttgccaa tacgaatttt
     2221 aagcagaata tcatttctct ttttagaatc aaaaggacga gattgtggaa tctctacagg
     2281 aacaataggt tgtggcatta aaatatcctc caatagtttt actttactaa tagtatacag
     2341 gaggagctcc atgaatgata gataccttgt tatgacgcgc ttaccatatt agaaagttgg
     2401 ctctctaatt aaattaattc tcattatata tatcaaaaga ccgcagtttg aaaactacgg
     2461 tctaattttt tgtccaaatg taaaccactt ggaactatta ttcaatttat tctttttagc
     2521 aaatgttccc gttttaatcc cagttacagt ttttaatcct ttgtaaccgt tgattttaca
     2581 aagcttttaa tttttttgcg attactccca ctcaactgtt gcaggtggtt tacttgtaat
     2641 atcgtagacg atacggttaa catgatccac ttcatttacg atacgtactg agattttttg
     2701 aagtacttcc catggaattt tggcaaaatc agcagtcata ccatcgatag aagtgatagc
     2761 acggattgca atcgtgtagt catacgtacg accgtcaccc ataacaccga ctgaacgaac
     2821 gcctgtgtta acagtgaagt attgccaaat atcgcggtca agtccagctt tagcgatttc
     2881 ttcacgaaga atagcgtctg attcacgaac ggtttcaagt ttctcttcag tgatttcacc
     2941 catgacacgg atagcaagtc ctggtcctgg gaatggttgg cgccatacga tatggtctgg
     3001 cataccaagc tctgtaccaa gagcacgaac ttcatccttg taaagagtat tgagtggttc
     3061 aatcaattca aactgcatat cttctggaag accacccacg ttgtggtgtg acttgatagt
     3121 ttgagctgta tccgtaccag actcgataac atctgtatat aaagtacctt gagcaaggaa
     3181 tttcacatct ttgagcttgc ttgcttcgtc atcgaataca tagacaaact cgttaccgat
     3241 gattttacgt ttttgttcag gatcagaaac gccagcaagt ttgtcaagga aacgtttagc
     3301 agcgtctgct ttgacgatat tcaaaccaaa cttaccaccg agcatgtcca taacttgatc
     3361 agcttcgcct ttacgaagaa gaccgtggtc cacgaagata cagatcaatt gatcgccaat
     3421 cgctttttgg agaagaaccc caacgacaga tgagtcaaca ccacctgata gaccaagaag
     3481 gacacgttta tcaccgacgg tttcacgaat ttttttgatc tgcatgtcaa tgaaattatc
     3541 cattgaccag tcacctttag ccttacaaat gttaagggca aagttacgaa ggatatcatt
     3601 tccgtataca gaatgacgaa cttctgggtg gaattggata ccgtaaatgt gtttatctgg
     3661 gttttcgatg gctgcgtatg ggcagtcagc tgatgtacct gtacgaacaa agtcagcagg
     3721 aatctcagta accgcatcac catggctcat caaaacagtc tgttcatcag gtgttgattc
     3781 aaaaagcgct gatggtgtgt gagttagggt tgattgaccg tattcacgat ttccagcatc
     3841 acctgcagga acaacttttc ctccaagttt atgggtcaat aactgcatac cataacagat
     3901 tcccaaaatt ggaattccga gttcgaagat ttctgggtca atatcaaatg aaccatcttc
     3961 atatacagaa tttggaccac ctgatagaat aattcctaca ggattgactt cacgaacttc
     4021 agcagctgaa attttatggc tttttagttc tgaaaaaaca ccaatatcac ggatacggcg
     4081 tgaaatcagc tggttgtact ggctaccata gtccaatacg atgatttttt ctacatcttg
     4141 caaatcagtt gaaatgttgc tcatcttttt cctttctcaa aagaaatatc ttttctcaat
     4201 attctatcac aaataagggc gaattaccaa ctaaacaagg cgaagtttga ctttttctag
     4261 tttattgggg tacaatagag aaaagataga aatgaagtga aaaatatgct acctgcttat
     4321 atgaaaatcc atgatcagat aaaaaaggat attgacgagc accgttgggc tattggtgag
     4381 aggcttccca gtgaaagaga tttagctgag cagtttgcgg tcagtcgcat gaccctccgc
     4441 caagccgtat ctctattagt cgaagaaggc gtcttagagc gccatgtagg aagcggcacc
     4501 tttgtttcca gtactcgagt acaagaaaag atgcgaggga caaccagttt tactgaaatt
     4561 gtcaaatccc aaggtaaagt tccctctagc cagctcattt cctacaaaaa aaccattccc
     4621 aatgagcaag aagttgccaa gctaggaatt tttccaacgg acaatattat ccgaatggag
     4681 cgggtccgct atgccgacca agttccccta gtttatgaag ttgcttctat tcctgaaaaa
     4741 ttcattaagg actttaaaaa agaagaaatc accagtcatt tcttccaaac cttgcaaaaa
     4801 catggctatc gtatcggcaa atctcaacag accatctatg ctcgccttgc taaagaaaag
     4861 attgcccact atttggaagt tgaaaaagga catgctattc ttggattgac ccaggtttcc
     4921 tacctagaag atggtactgc ttttgaatac gtaaaaagtc aatatgtagg cgaacgcttt
     4981 gaattttatc ttgaaaataa ttagattacc acgcaaaaac tctctgtcac ggacaaagag
     5041 tcttttttat ttttctaaga ataaatcttt caaagaaatc aaagttacag caaacaatat
     5101 cattgccata ccaagaaaat caatgggata aaattgttca ttcattatta agaaggcaaa
     5161 gaaaatcgcc gatattggct caattgaagc caacaagctt gacttgaccg gtcctatcag
     5221 actggctcct ttaaggaaag ctgtataggc aaagacagtc ccgataagga taatgcctgc
     5281 aaacgcaagg agaaaatcaa gactagtcgg gatatcggcc tgtagaaccc ctgtaaaagg
     5341 aagagcgacc aaacctgcta tgaccattcc cacaccaatg accaagctgc tcccccactt
     5401 tttaatcaag gctatgggta aaatgatata cagagcataa gtaaaggcag aaaagagacc
     5461 ccagaacaga ccagcaggtg tcatggataa ctggtccaac tgcccatgtg ttgcgatcag
     5521 gaaggttcct ccgatggcga atatgatgga aactatctct cccagtgtcg gtgccaccct
     5581 atccttgata cagctataaa ttaaaattcc gacaggacaa acatactgaa gcaccgtcgc
     5641 tgttcccgca ttggtctcct gaatagcaga cagataggcg aattggttga gaaaaagacc
     5701 aatcagagca aaaataagaa gagacagcaa actctttcta tcctttaaaa agaccagtat
     5761 tttatccttt gcagtagcat aagccaagag catgagaatt ccaccagcga ttaaaagacg
     5821 caagttggtc aagaccagag ccgaaattcc gtgtgccatt aggtattggc cactcgttcc
     5881 tgacaacccc caagcaatac cagccacaac tgttagtaaa gtccctttta aactatttga
     5941 catgtctctc cttactcttc tttgcgaatc aagttcatca cttgattgcg gtctaatatc
     6001 cattgagctc tctcgtcctt ttcataggta cgattcgata ggaaaatagt ggcttcttgc
     6061 ttctgacgat tccacatgat aaaggtacct gtatagcccg tatggtctag ccaatctcct
     6121 tccaaattcc atgctaaaga acgttccttg tcatccaaag gagaaaaatt ttgacttaag
     6181 tctcttgcaa aatcatctgc taaatagtgt tctaaaaaga tttgtaaatc ctttatagtc
     6241 gaaaataaac cagcactccc agcatgtcta cccaggagac gagccttggg atcatgcact
     6301 atgcctgcct ctacacctct aactgttgga acagcaagct caactgaccc aaacttggtt
     6361 tccgtcattc cccaaggttt ccagacttga tcctttaaaa tcacatccaa atcttgatta
     6421 aaaattcttt ccaaaataaa gcccaacagc aaaaaatgga catccgaata aagaaaggct
     6481 ggctgacttc gtctgttgag atgaaacatc gcttccttta attcaggggc tgttaaaaga
     6541 tcacgattag gaataaaagg atcaaggtct gttgcatgag tcaagagctg gcgaatagtg
     6601 atgtctggat aatcactctc aggtaaaaaa tctattacca gtctatcaat atctaattga
     6661 cctatttccc acaagaaggt acaaactgtg ccaaccccaa caaccttgct gacactagct
     6721 aggtcataaa ctagtcctgc ctcagtctgc aagccatgct ctgggtcact ctggcctaaa
     6781 tagaactctg tccattgatt gtccttaaaa tacgcaaaag aggctccggg ataaattcct
     6841 gcctcgattt gttcttctat ttttttaata atcttggtcc acttcatact tcttcaaacc
     6901 acaattcaac attatttcta tctttacaaa ggaagaattt ttcagactta ggaataaaat
     6961 attcagtaga ctcaaacttc tggcgaagac ttgctatgtc taattcattg accaagaact
     7021 tgagcataga taagtcccag gtaaccgtat tgtccacagt caaatcctgc ccctgagctg
     7081 gaataaaatc aagggatgcc ccaatttcag atgattccaa gaaactttcg atatcagttg
     7141 ggagatgtaa ttccatagaa atctcaaatt tacttaaaga aattgatacc aaatctgttt
     7201 gaaattcagg cttttctcct acttctacta gacttgctct gtcatcttcc gcatgaatca
     7261 aaatcaaatc atcttctggt gagaaaattt caaaagcgta gccattttga cctttatata
     7321 atcgatgaat cgaatctgtt ttagataaga ttccttcaat ttctaaggga ttttccacct
     7381 tgacaatcaa tctagctagt ttttttcttc cctctacctt acgagtacgc atactgggag
     7441 cttcttctaa aaccagcttt tcaagacccg tttggtcacc tagtgacaga aaggccgatt
     7501 cttctaacaa ggccttcatt ccaagggttt caatataaaa tgtttcattt aattttctat
     7561 tattagcttt taaagtagga ataatccgta caatctgatt tacattcata aattcctccg
     7621 tcacttttta ttttaaagga ttttagaatt ttttacaaga tattatgctc aaatttaaca
     7681 ttatttagct atttagtaaa gatagtcttt caaggctttt gacaaagcct gataaccagc
     7741 aatactgagg tgcagtccat cagttgtata ttcttttttg agttggcctg cttggtctgt
     7801 caaacaatca aatactggca caaattccac ctgcatatag gcagatgcaa gctcttgata
     7861 ggcttgattc cagttctgaa ttttttcatt cgagcggata tagactgcct gctggtactc
     7921 ctctccctca ttgacaggca aaatggaaag caatttaatc tctgtcaatg gataatcgcg
     7981 agcaacggat tgaatgatag cttcgagatt attgagagcc tcattcacag gaacatcctt
     8041 tccgatatca tttgtcccaa tcagaagaaa aattttatct actgctccac catatagatg
     8101 agcatcaagg ttctctagta acagtcctgt ctgatagcca cgaattcctc gattgacaat
     8161 cgtctttgaa gtcccaaata gctcctgtag aggataatac tcgacaatgg aatccccaat
     8221 aaaaagaatg tttggttcta caacagaaat gtgatttagg tgacgatact tagtttgaat
     8281 tttttcttgt tcctttagga gccaattttc taataactgt actgccactt cattctcctt
     8341 tttctaacca gttttccaag acttgataaa ctcctccttg gctgttggct ggtgctagag
     8401 cagtcgccac agctttggct ttctcatcag cattttccat cgcataggca attccagcca
     8461 tttcaagcat ttcaacatca ttttcactat caccaaaagc catgatttct tgggatttca
     8521 agtcccagcg cttgagtaat tcctccaagc cccatgcttt atgaatccca gcttggagga
     8581 tatcaatgca accatagcca ctggatacag ctcggacacg gccatcaaag agagcattga
     8641 tttcttccaa aaccgaactc aaacgttcct caccaacaac catgctcatc ttgagcacac
     8701 caccaaagag gtcagatgtt aattcatcca caaattgcat ccgttggtag aatttttcaa
     8761 tcatttctgg agtcataaaa ctttcaagat ctgtaaaaat cgtaccttcc ttgacaaaat
     8821 cacccttcat ccccgttaca acaaactggt cctgacacgc tcgacccttg aaatgagtca
     8881 aagccttgtt gacaatggcg tcatcccatg tctgagcctg aatcaattca ttgttttcaa
     8941 aaatacgagc gccattagca acaaccagaa ccactcgatc caccaaggga ctcagtagtt
     9001 gtctcatgcg gtgaatttca ttgcccgtcg caatgacaaa acgaatgccc ctttgatcca
     9061 actgatctaa aatcttttcc aatcgtggga gatcaagctg acctctagca tccagcaagg
     9121 tcccatccat atctgtcgca attaccttaa tcatcattta ctttcctctg gattcaagct
     9181 aataccactt caatcccaca tgttcattca tttctttata ggctgtatca attcgttcct
     9241 tagtcgcttc atctaactgg tcacgatgac tgccatcctc tataaaatct tccaaaatat
     9301 aagtttggta atgatacaag ggatatcctt ctggtgaaaa ggttcccttt ggtgttcgat
     9361 tgacccaagt aggatgagct ttagctgttc cgatagttgt ttttccatcc ttcttcttga
     9421 tggtgacatc catgagaaca ccacgttcag tccacttagc attctcttca tctcccatag
     9481 attcaatccg ttgattggaa atgaagttcc ccatttaata gacaatgagc ttcttatctc
     9541 catctttttc caccgtttca gatggttcaa caacgtgagg atgccctcca aagataatat
     9601 ccgctcccca atcgatcatc ttgtgataaa gagctttttg ttcttcagtt ggttccaatc
     9661 gatactcaac acccatctga agcatgataa tggtgatatc tgcttccttc tctgcccgtt
     9721 caatttcaac cttcatctta tcttcgttta aatctgaaag ataacgatta tagtcttcct
     9781 gagaaatata ctgctcaatt ccattgaaac cataggaata ggctaacaat gcaaccttga
     9841 taccattcac ttccttaatg accagcggag cctgaacacg tggttcgtgc gtataaactc
     9901 cgattggagt gattccagct ttctcaataa tatcggccgt tgaaataact ccctcaagtt
     9961 gaaataactc cctcaagttg cgaatccaaa atatgattat gagctaaatc cagcacatga
    10021 taacctgcct ccttaatagc atccataact tcagcaggag cattaaagag aagataaccc
    10081 gctaaataat gatccttatt aatggttcct tcaaaatcac caatagctaa atctgcttgc
    10141 ttgagccaag gagtcacata ctcaaaattt tcatgaaagt cataggtacc gtcttctttt
    10201 ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc cgtgggccat aattctggca
    10261 gttttttcct cttcctactc ctgagacttt tgcttagtcc cctcttgaga aatagtatct
    10321 cgtttttgac tagtcaaggg attccttgga agctttcaaa caacaagacc aagcccttca
    10381 taaaacgaaa agctaaacca ccctgatttc gattttatct tctttgtatc ttcattctcc
    10441 ctactttctt atgcaagcct tttcttttta ttatatcaca gataagtatt tctttcacaa
    10501 ttgaattgaa cttcccatct attttctata aatcctaaat gccataatgc tttcaattct
    10561 tgtcattttg tgatatcatg tagaggaaat gaactaatcc acagtggctt atttcaagta
    10621 taccacttgg gctttggcag tagctaactg cactaaatat aatataagga gagaaaatgt
    10681 ctgcaataga acgtattaca aaagctgctc acttaattga tatgaacgat attatccgtg
    10741 aagggaatcc tactctacgc gcgattgctg aggaagtcac tttcccccta tctgaccagg
    10801 aaatcatcct aggcgaaaag atgatgcaat tccttaaaca ttcccaagac cctgtcatgg
    10861 ctgaaaaaat gggactccgc ggtggtgttg gactggctgc tccccagtta gatatctcaa
    10921 aacgcattat cgctgttttg gtacctaata ttgttgaaga aggcgaaact ccacaggaag
    10981 cctacgattt ggaagccatt atgtacaatc caaaaatcgt ctctcactct gttcaagatg
    11041 ctgctcttgg cgaaggagaa ggttgcctgt ctgttgaccg taacgtgcct ggctatgttg
    11101 ttcgccatgc ccgcgttact gttgactact ttgacaaaga tggagaaaaa caccgtatca
    11161 aactcaaagg ctacaactcc attgttgttc agcatgaaat tgaccacatt aacggtatca
    11221 tgttttacga tcgcatcaat gaaaaagacc catttgcagt taaagatggt ttactgattc
    11281 ttgaataaag aaaatcccgt tgcaagacgg ggttttgtgt tataatagag gcatgaaaac
    11341 aaatgatatt gtctatggcg tccacgccgt taccgaagcc ctccttgcaa atacaggaaa
    11401 caaactctac ctccaagaag atctccgagg taagaatgtt gagaaagtca aggaactagc
    11461 tacagaaaag aaggtgtcca tttcttggac atcaaaaaaa tctctctctg agattactga
    11521 aggtgctgtt catcaaggtt ttgttctacg agtgtctgaa tttgcctata gcgagctaga
    11581 ttacatcctt gcaaaaacac gccaagaaga aaatccactt ctattgattc tagatggtct
    11641 aaccgatccc cataatctgg gttctatctt gcgaacagcc gatgcgacca atgtttcagg
    11701 tgtcatcatt cccaagcacc gtgctgtcgg agtaactcct gtcgttgcca aaacagccac
    11761 aggtgctatt gaacacgttc caattgcccg agtgacaaac ctcagtcaaa ccttagataa
    11821 actcaaggat gaaggcttct ggacctttgg aacggatatg aacggtactc cttgccacaa
    11881 gtggaataca aaagggaaaa tcgccctcat catcggaaat gaaggaaaag gcatctctag
    11941 caacatcaaa aaacaggtcg atgaaatgat taccattccg atgaatggac atgttcaaag
    12001 cctcaatgcc agtgttgctg cggccattct catgtacgaa gtttttctaa atagactata
    12061 aaaaagtttc cagtcatctg attggaaact tttttataat taactatgtt ctgtgataaa
    12121 cttgtaggct tcttgaccag cgatagctcc atctccaact gctgttgtta cttggcgaag
    12181 gtctttcaag cgaacatctc caactgcaaa gataccgtcg actgcagtct tcatgtggct
    12241 atctgtcaca atccagcctg cctgatcttg gatattcaat tctttaacaa aatcgctaag
    12301 agggtccaaa ccaacataga taaagacacc accgaaggct tgctctgtca cttgacctgt
    12361 tttcacattt tcaaaaacga cagattctac tctgttttca cccttgattt ccttcactac
    12421 agaatcccag ataaagctga ttttttcatt cgcaaaggcg cgatcttgta aaaccttttg
    12481 ggcacgaagt tggtcacgac ggtgaacaat ggtaacagtc ttagcaaaac gagtcaagaa
    12541 gagggcttct tcaacagctg aatctccacc accaactacc aataaatctt ggtcacggaa
    12601 gaaagcacca tcacacacag cacagtaaga aacaccacga ctgttcagtt cttcttctcc
    12661 aggcactccc aaaggacggt gtttagaacc agttgctacg ataactgtac gtgtttcata
    12721 tgtttggtca tcagtcatca ctttcttaaa atcaccatgg tcttcgacat tttcaacata
    12781 accataaatg tgctcaacac caagattttc aagtggttca aacatctttt cagccaattc
    12841 aggtccacta atattagcgt atcctgggta attttcgata tcagatgtat tattcatctg
    12901 accacctggc agaccacctt caatcaaagc tacttttaga ttgcttcgag cagcatacaa
    12961 ggccgcagtc atccctgcag gtccagcacc gataataata gtatcgtaca tatagattcc
    13021 ttctttcttg ttgtaactat ctttattcta actctttctt gtcaatcacg caaggattat
    13081 gccttgaaaa caagaattaa actcataacc gcaaaggata atactgggac aaccaagact
    13141 ccaatcataa tcatatcata gagatgggct tggcgagccc tggctgtctt atcaactccc
    13201 gacatggctc tcagaccaat ccaaatccct aaaaaaatca gaacaaggat ggtggtcaag
    13261 atcaaactct cgaaatataa agaaaatagt tgcagtagca tgatttctct catttctatc
    13321 ttttttaaag agtaaactca gctagtccaa ctaactgagt tttcctttat ctattatatc
    13381 aaatataagt ccgtttgtaa ctagcgaaga attcttttgt ccgctcttct ttaggggtgt
    13441 ggataatctc atccggagtt ccagactcga tgattttccc cttatctaag aagagaattt
    13501 tatccgcaac ttgggctaca aaggacatgt catgactgac caaaatcatg gtctgacctg
    13561 acttagcagc atctgcaata gacttttcta cttcaccgac caattctggg tcaagggctg
    13621 aagttggttc gtctaagagc aaaacatctg gtttcatagc aagcgcacgc gctagggcaa
    13681 cccgttgctt ctgtccacct gataaatggc gaggataatg gttttcacgg tccgaaagcc
    13741 caaccttagc caactcttcc ttggcaatct tagtcgcttc ttggtcagat aatttcttga
    13801 caacaaccaa gccttctttc acattatcaa gtgctcttcg acgttcaaat aaattaaact
    13861 gttggaaaac catagacaac ttacggcgta gggcaaggat ttcttcttga gtgattttag
    13921 aaaaatcaac tgaaaaacca tcaatctgaa tagagccact gtcaggtgtt tcaagataat
    13981 tgagactgcg aagaaaggtt gattttccag ctcctgaaga accaatcaag gctacaactt
    14041 cccctttttg aatatccaag ttcagatgat ccaagacagt ctgtcctgaa aaggatttgc
    14101 ttaaattcga aatcttaatc attaacgaag gtctcctttc acatctgttt gcactgtatc
    14161 aggtgcagaa atagccattt ttctctcgat gaaacgaccg aggctttcaa ttccgatatt
    14221 gactacccaa taaacaaggg caacagagat gaagcgttca aaatagcgat aatcagctcc
    14281 acctagaatc tgagcttggg caaagacttc cacaacaccc gcactaaaag ctagagatgt
    14341 tcccttggtc aaaccgatga gggaattaat caaggttgga gtagctacca ccgctgcatt
    14401 aggaataatc actcgtcgat aaacttgcgc tcgggtcata cccagactgc gcgccgcctc
    14461 aatctcacca ggattaactg agagaatggc tgcacgaatg gtttcactag cataagctgc
    14521 ctcattaaag gcaaaagcga caatcgcaaa agctgcagct ggaatcgcat tgatattgag
    14581 accagttccc cattgctgat tgagggcttt caaagccaaa ggaattccgt agtaggtcaa
    14641 catgagttgc accaaaatcg gtgtcccttt taagaaacta acaaagaagg cctgcaaggg
    14701 atataaaatc ttgacacgat tgatcttcac aatggcaaaa agaagcgcca aaaccaagcc
    14761 aaaaagggca ccaccaattg tcaacataat tgttgttgga agttgttgga caattctagg
    14821 gattccatca aagaccgaac gtaggctaaa cagcttgcca tccggaatca attgcatcaa
    14881 gttttggtac caatctgatg ctaaaatcgt tgtaacattc ataaaaacat cctcttctga
    14941 taatgattca ttctaccatg cttctgccgt caatgaaatt atttgctacg gtcagataca
    15001 gactttgtct acctactagt ttatcatact ttgaaacagg gaagttatat attttatcta
    15061 tcaaagagat agataaaaac tatttcagtc ccagttcttc ataagatttt cgataaccga
    15121 tttgcttaac agttccattt tctactaaaa tgggccgttt taacaacata ccgtcacttg
    15181 ctagcaactc agccgcttct tggtttgaca aacttcctac cttatctttt agccctaatt
    15241 cacggtattt gataccactg gtgttgaaaa attgcttcaa ttcaaatcct gaggtttcta
    15301 gccaattcaa aatgacttct tggctaggtg tttcttccac gatatggacg gctttatagt
    15361 ccacacctaa ttgatttaat tcttgttttg cttttttaca agttgaacat ttggggtatt
    15421 cgataaattc taacatgtgc ttctccttct atttgtttat atctttaaaa tctacgcctt
    15481 catgctccaa gagccaagct ttcttttcca ctcctgcagc atagcctgtc agacgcttgc
    15541 ctgctcccaa cacacgatga caaggtacta ggatagacca aggattgcgt cccactgctc
    15601 caccaattgc ttgagcagaa gccacttgca ggtcttgagc aatttgtcca taggtcactg
    15661 tctgaccata aggaatgccc tgtaaatagt cccaaactct cttttcaaaa ttcgttccga
    15721 ttggcgccaa gagcaagttg gataaatcct gaggcttgcc tttaaagtaa tcatctaagc
    15781 aagcaataac tgggtctaaa ataggatgac taacaacttc ttctatcgtt tcatctccta
    15841 gtcccctctc aaaatgcttc tgctcctgaa cccaaattcc atacaaataa tggtcatcag
    15901 ctacaagtga tagaatacca attggtgagg agtagaggat ttttacatac ttcttttgca
    15961 ttatttcttt aatttttgat aggccaagcg ttcgccatct actggcacct taccaacttg
    16021 tttaaaacca agtttttcaa aaatatgttg cataaccttg ttttcagcat gcgtatctga
    16081 gcgaaaatca agataatcaa aaccttcaat caagccctct aagaaggttt gagcaactcc
    16141 ttttccctgc acatctgctg ccacagcaat acggtgaaag actagatact ctgactctcc
    16201 agcttgccag tttccctcat aaatagcttc ataggcctcc tctggactct tggtcacagc
    16261 agcataggct agcagttctc cctcttccaa ggctacgtag gcttgccctg agatgatatc
    16321 atcgataata acatctgcat ttggatagcc attttgccac tggttactac cagcatctgc
    16381 taaacatttt ttggcatcct ctatcacctg catgatggca tctacttcat ttggaaaagc
    16441 taaacgaatt tccatctttt ttcctcattt ctgactagtt tctcccatca tagcataatt
    16501 taagtctttc tacaagcagt taaaacttga ctttgtattt ttgttatttt ataatctagt
    16561 tatcaaaact atataaaaag gagttgaaaa tgaaaactac cttttcctac ccaaaatggg
    16621 cagaaattcc aaacattaac ctctatctgg accaggtttt gctctatgtc aatcaggtct
    16681 gcgcccctat ctctcctaat aaagacaaag gcctaacagc atctatggtc aacaattatg
    16741 tgaaaaatgg ttacctgaca aagcctgaca aaaaaaaata ccaacgccaa cagattgccc
    16801 gtttgattgc tatcacaacc ctcaagtctg tattttctat tcaagaaata gcccagacac
    16861 ttaatactct acaaactcaa gcaagttcag accaactcta cgatgctttt gtggactaca
    16921 tgaaccaagg aattgaccca gctaacccta ttatccaaac cagctgccaa accgttaaac
    16981 tctatcatca aactctagac ttaatcgatc atactcaaga ggaggtaatc caatgaacac
    17041 tagtcttaaa ctcagcaaac aactcagttt tggagaggag attgctaata gcgtgaccca
    17101 tgctgtgggt gcagtcatca tgcttatctt gctgcctatt tcatccatct atagttatga
    17161 agcacacgga tttttatcct ctatcggcgt ttccattttc gtcatcagtc tctttctcat
    17221 gttcctatca tccaccattt atcactctat ggcctatggt tcgacccaca aatatgtttt
    17281 gcgaatcatt gaccattcta tgatttacgt tgccattgcc ggctcataca cgcccgttgt
    17341 cttgaccttg atgaataact ggtttggcta tctgattatt gtcatccaat ggggaacgac
    17401 catctttggt attctctata aaatctttgc taaaaaggtc aatgagaaat ttagccttgc
    17461 tctttacctg attatgggct ggttggttct ggctatcatt cctgccatta tcagtcaaac
    17521 gacacccgtt ttctggagtc tcatggtaac tggcgggctc tgttatacag ttggagctgg
    17581 attttatgcc aagaaaaaac cttatttcca catgatttgg catctcttta tcctagctgc
    17641 gtccgcactt caatacatcg ctattgttta ttacatgtaa aaaagttgag aaattcaatc
    17701 tcaacttttt tctttacaca tattgataaa gtactggtgc aagcgcacat catcagtcaa
    17761 ttctggatga aaagaactta ccaacatatt tttttcttgg gctgcaacaa tttgattgtt
    17821 cactgttgct aaaatttcta caccctcacc aacactactg ataatcggac cacggataaa
    17881 ggtcattgga atcttgccaa ctcccttaca ttctgcttcc gtgtagaaac ttcctaattg
    17941 gcgcccataa gcattacgct cgaccaccat atccatagtt cctagatgac tctctttctg
    18001 agaagtgatt tccttagcca gcaaaattaa gcccgcacag gtcccaaaca ctggtaagcc
    18061 agatagaatg gcttctcgga tgggaagtag catgttctgg tcacgtaaga gcttgcccat
    18121 ggttgtagac tcaccaccag gcaaaatcaa acccgacaag tcactctgat cttgctgaaa
    18181 atcatctaga tttctgagtt ctacactctc gacacctaat tgatctagca cttttgcatg
    18241 ttctgcaaag gccccttgca aggccaatat tccgattttc atctattttc ctcgttcagc
    18301 catgagaatt tggatttcat tttcattaat accaaccatg gcttctccta aatcttcaga
    18361 gatttgagct aggatttgag gattacggaa gttagtcaca gccttaacaa tggcactcgc
    18421 tcgtttaaca ggatctcctg acttgaaaat acctgaaccg acaaagaccc cctctgcccc
    18481 taattgcatc attaacgcag catctgctgg cgttgcaaca cctccagcag cgaaatttac
    18541 aactggcaat tttccatgtt catgaacata ttggaccaat tctacaggga cttgcaaatc
    18601 cttggcagca acataaagct cgtcctcacg taagttttga atgcggcgaa tttcctgatt
    18661 catcatacgc atatgacgaa cagcttggac tatatcccct gtccctggtt ctcctttggt
    18721 acgaatcatg gaagcacctt cagcgatacg acgcaaggct tcacccaaat ccttagcacc
    18781 acagacaaaa ggaacttgga attctttctt gtccacatgg aaacggtcat cagctggaga
    18841 tagaacttca ctctcgtcga tataatcaat ttcaatagcc tctaaaatct gagcttcaac
    18901 aaaatgcccg attctgacct tagccattac tggaatacta accgcttctt ggatttcctt
    18961 aatcatcttt gggtcgctca tgcgggaaac tcctccagct gcacgaatat cagccggaat
    19021 tcgttccaag gccatcacag ctgccgcacc agcagcttct gcgatacgag cctgttcagg
    19081 attctgcaca tccataataa caccaccctt gagcatctgt gccaagtttt tatttagttc
    19141 ataacgattt tcagtcattt gttttatcct catcatttgt attggtagct accttttcat
    19201 tttaagtcag aacagaatga agcacaagat aaaaaaacta taattgtatg gggacagatt
    19261 agctaaaaac tatctgacct taacttaagg ccagatagct cattcatttt tatttttcag
    19321 ccgtaagggc agccattgtg atgtagttgt atggtttgtt gaagtgtggc aagaagaaga
    19381 ggtctgtcaa tgccaattta tcaattgtca catgctcttg gatagcaagt gagaacatgt
    19441 ggattcccat gctaattgca atatcatgtg aaaccatttg ggcaccaaga atttcacggc
    19501 tatctttgtc aaagacaatc ttaattgcta cttcatggtt gtcatgtttc atgaattctg
    19561 gtttttgaag atcgttaaag cctgtttcag ttgcgttgta accagcagct ttcgcttttt
    19621 caagagtcaa accagttgaa accatgtgaa gaccgtagat tgagatacca tttgaacctt
    19681 gaacaccgat tccttccaat tcatgtccac aagcattgta ggcaccaacg ataccagtgc
    19741 gaacagcatt tgaagcaaga gcgatatagc ttgtatcttt acgagcattg tcataaacag
    19801 tcgcacagtc accaacagcg taaacgcctg ggatagatgt ttcttgtttc ttgtctacaa
    19861 ggaaggcacc gttgcggaag agttcgatct taccatctgc aagggctgtg tttggacgga
    19921 aaccaactgc aaggataacc atatccacgt caaagctttc tttgtcagta atcaagcgtt
    19981 caactttacc gtcaccttcg attgctttaa cagtttgacc tagagccaag cggatgttgt
    20041 gatcttccaa gttcttcgcc atcatttgtg tgaagtcttt gtcatagtaa ccgttcaaga
    20101 cagtatcaac gatatcaaca aggacaactt cttttccaag acgttcaaag gcttcagcaa
    20161 gttcaacacc gatgtaacca ccaccaacaa cggcgatacg gtcgaggtgt tggctcttgt
    20221 cagaaagttt attgataact tcttcagcat tttggtacaa tttcacgaat tgtacgtttt
    20281 caagagttgc tttaaattcg cggtttcctt taacaatttc aacaccttcg attggtggca
    20341 agattggtgt agaacctgta gcgaaaatca atttttcgta tgattctttg tgctcttttc
    20401 cttcaacttc cgctgtaact actttgttat catagtcgat tgaaagaaca ggtgagttca
    20461 tgtaaacttt agcaccttta gcttccaatt tttctttatc agaatagaac aagccttcag
    20521 caccgtcaat ttgttcacca atccaaagag ccattccaca tcctaggaaa gagatgttag
    20581 agttttggtc aaatacaaca atttcgttct catttccaaa attatccaac atggtattga
    20641 tacatgctgt accagcgtgg ttagcaccga ctacaacgat tttactcata aaaatttcct
    20701 gccttcattc taaatttacc ttactagtat accatttacc gttagcgttt acaagggggg
    20761 tactattatt tcagcatttt ttatcaaaaa taattcccca tttatcctgt tttcaagcct
    20821 catgaatttt atgagcatat ttcttgactt tttccaaatt ttgtttgtga aaattctaac
    20881 tttatggtat tataataaca tgaaaatgaa atgtaagggc ttcaatttag atgattattt
    20941 gatattacaa cttattttct ataagagaaa ggagttggta gcttgactct tcgttcacat
    21001 tctgaacggc taatggggac tactatcact atttcattag tggatgagca agccgatatc
    21061 tttctccaaa aatcctttga cttgctcaaa gaacttgaat accgcttcaa cgccaatagt
    21121 caagaatctg agttgatgga aatcaattat caagcaggaa tagcccccgt cacggttcat
    21181 ccagacctgt ttgagctgat ttcacttggg ttagagcata gcctagcgct ctctagccac
    21241 ctcaatatca gcattggtcc cttaattcaa acctggcgta tcggtttttc agatgccaag
    21301 gtcgcccagc ctcaagaaat tgaatcggtg ctgcctctaa tcaatcctca tggtatcgag
    21361 ttagattctt ctacttctac tgtgttttta aaacagaaag gaatgaagat cgatctaggt
    21421 tgtttagcca aaggatacag tgcggataag gttgcccaat ttcttaggaa agagggggtg
    21481 acttctgcct tgatcaatct gggagggaat atcctgacca ttggaaaaaa tcaggcaaga
    21541 ggggataacc catggcaaat cgggattcaa gacccagcca atcctagggg aaatcattta
    21601 atgaccatcc ctgttgtcaa taaatctgtc gtgacttcag gcatttatga acgtcacctg
    21661 accgtcgatg gacaagatta ccatcacatt tttgacagtc aaacaggata tcctgttgaa
    21721 acggaactag cgagtctaac aatcatctct gataaatcag tcgatggcga aatctggacg
    21781 actcgactct ttggagaaag acctgcttct atcctctggc aagtcgaaag tttggagggc
    21841 atcgaagtca tcctcatcga taaagaaggc cacctaagct gttcttcagg aattcctact
    21901 ctatagagac aactgtttca atggaatttt aaaattgtat tatgtaaaaa gagaaaggaa
    21961 atctcatgtt aaaacttatt gctattgttg gaacaaattc aaaacgttct acaaaccgtc
    22021 aattgcttca atacatgcaa aaacactttt ctgacaaagc tgaaattgag cttgttgaaa
    22081 tcaaggccat tcctgtcttc aacaaaccag ctgacaagca agtacctgct gaaatattgg
    22141 aaattgctgc taaaatcgaa gaggcagatg gcgttattat cggtactcct gagtatgatc
    22201 actctattcc agctgttttg atgagcgctc ttgcttggtt gtcttatggt atttacccac
    22261 ttttgaacaa accaatcatg attacaggtg cttcttacgg tacgcttggt tcatctcgtg
    22321 cccaattgca acttcgtcaa atcttgaatg ctcctgaaat caaggcaaat gttcttccag
    22381 atgaattctt gctctcacac tctcttcaag catttaaccc aagtggcgac ttggttgacc
    22441 ttgatgttat caagaaattg gatgccatct ttgatgactt ccgtatcttt gtaaaaatca
    22501 cagaaaaatt acgtaatgca caagaattac ttcgcaaaga tgctgaagac tttgactggg
    22561 aaaatttgta agataggaga ccaaaaagaa tgaaatttgt tggacttgtt ggatcaaact
    22621 acgatcaatc atataaccgt aagctcttgg aatttatccg tcgctacttc aaactcaaat
    22681 ttgaattaga agttcttgaa attgacgaag ttccaatgtt taaccaagat gaaaaatggg
    22741 atgaaagttt ccaattacgt tatttatata acaaaattac tcgtgcagat ggtgttatca
    22801 ttgctactcc tgagcataac cacactatct cagcttcact caaatctgta cttgaatggc
    22861 tttcatacga agttcatcca tttgaaaaca agcctgttat gattgtgggt gcatcatact
    22921 atgaccaagg aacatcacgt gctcaagttc accttcgtaa aatccttgat gctccaggtg
    22981 ttaatgccta cacgcttcca ggtaacgaat tccttcttgg taaagctaag gaagcttttg
    23041 ataacaacgg aaatatcacc aacgaaggca ctgttaaatt ccttgaaact tgcttagata
    23101 actttgttaa atacgtagga gtcgtttcga aattgaaaaa accaaaacca atcgaatcag
    23161 aagacttgga ttgtggaaaa ccaatcgcta caaccatcac agaagttgac cctgacgatc
    23221 cagaatgggt agaaaaagtt gcagcaatca ctggtgctgt ttctggtgat acctatgtca
    23281 aattggacca cggtatccta acagttaacc aaattgatat gttcttgaaa gctatgccat
    23341 ttgaattgac atacgctgac gacaacaacc aattcctcta ctacaacaac gctcaccaag
    23401 atccagacac tatgttcgct aaacgtgtac cacctcaatc aggtagccgt atgtcgactg
    23461 ttcatggttc tcttccacca gcacgtatga agaacgtaga gtgggttatc ggaacacttc
    23521 gcaacggaaa ccaagaatac gtccgtacga tcgttccagg ttctcctgca ggtgttatca
    23581 acactcacaa ctaccaagca atgtactatc ctgatggatc atacgctggt atcaatgaaa
    23641 tcgtctttaa cttccaacca tggcttgact ggtacctaaa agagactggt caacgtttgg
    23701 tgggtggtag cggaccattt gctcctgctg ccggaggtca tggagacgcc gatgctactt
    23761 ctggcgcttc tgattcaggg gatgctggag gccacggtgg tgacgcagac gctacagccg
    23821 gtgcaagtta ctaatgatag tttttaggaa ccattatggt tcctttttta gcgaaaaaag
    23881 actagcaaac acaaactgct agtctctttg ttatcgtttc atctatcttt gttaaaagaa
    23941 agagtactta tactcaatga aaatcaaaga gcaaactagg aagctagccg caggctgtac
    24001 ttaagtacgg caaggtgaag ctgacgtggt ttgaatttga ttttcgaaga gtattattat
    24061 gaatttgggt catcaagact acggccatgt aatccttttt cacgttgtac ttggcgtagt
    24121 ttttctggtg taacatcgtt tccttcttcg tccacaattt tgattccttc aatgtggtga
    24181 cgaacagcgc ggcgataacc ttcgatgtac tcctcacgta gtttggcttg ttccactttt
    24241 tcttctgatg ttaagccttc tgtttttttc tttttagcaa gctcattgat acgagcaatt
    24301 tttttcggat ccatttcttc tcctttgtaa taagataaag tccgtttatc aaattttatt
    24361 tagtgttaat ttggttaaaa caagcaaact tagctgcttt cttggttagt tgtgacaaga
    24421 ttgccaaacg attttgacgg acagcctgat cttcagccat taccatagta ttttcaaaga
    24481 aagcatcaat gactgggcta agcgcaaaga gttgtttcaa ttgctgactt gcaggtcctg
    24541 ataaaacgag tgtttctact gcttctgcca aagctttttc ttggtcattc tcaaatagtg
    24601 ctgaatcaac tgtagcaacc ccttctgcct tctcagccag gttaaaggca cgagaaagtg
    24661 attcaacaga tggtttaaaa tattcttcct tgcttacttc tacgagagca cttgctgctt
    24721 ccaacatatc tgccacaaca aagtttgaac ctgcaagaac tgcttccttg atatcttttg
    24781 gagtagagcc catcatctta tcaacacgag ccttgataaa gtccataacc tctgctttat
    24841 tttcataagt caaactgtca aatttcaatg cataaaggct atcaatcagc tcatccatag
    24901 caatgtgcca accaaaggca tccaagatac gaaccacacc ttgagttgca cgacgaaggg
    24961 cataagggtc attagaacct gatggaatca atcctactga gaagaaactc aaaatcgtat
    25021 ccaatttgtc tgcaatggct agaactgcgc cgaccttgct ctctggaagt tctccttcag
    25081 ctgatgtagg catgtagtgt tcacgaatag cagctgccac cgctggagtt tcaccagcaa
    25141 gaagggtgta tttttcaccc ataattcctt ggagttcgtc aaattcacca accatacctg
    25201 tcaataagtc aaacttgtaa atggctgctg cacgagcaag gtcaactgtt tcatccactg
    25261 acaaaccagc tttttctgcc aaaagtacag tgatttgacc cgtacgaatc atgtgttcac
    25321 gaagggaacc aatcttctca tggaaggtga cattgtttaa tttttcaaca agatctgaaa
    25381 tcaccaattt ttggtcttca cgccagaaga attctccgtc ttccaagcgg gctaccaaga
    25441 ctttttcatt tcctttaatg acatttttca aacgctctgc gtttccgtta cgaacagaaa
    25501 tgaagtttgg caagagtttt ccatcttgat cacgaacaac aaagtaacgc tggtgttcct
    25561 tcatagaagt caccaagact tcttctggaa cttcaaggta tttagcatca aaacttccca
    25621 tgaaggcagt tgggtattca accaaattca agacttcatt cagcaaatcc gcatcaattt
    25681 cgatacgtac accatgtttt gcctcaattt ccttgatttg gtcaacaatc atttgctcac
    25741 gttcacatgg atctgcgatt acaaactgct tacgaaggtc ttcttcatag ctcaatgctg
    25801 actgaatttt ggtttctttc cccaagaaac gatggccacg gctcacacga cttcccttga
    25861 tatcaaggaa atccaagtca aactcttgct catccaagag aacagttaaa gtgtggacag
    25921 gacgaatgta ttcaaagcta tttccagccc agtgcatgct gacagggaaa gtcaatgact
    25981 tcaagacatc tacaacacca ggaacaatgg cttcaactgc ttgaccaact tcttccttag
    26041 tgacatagac atattcttca cccttgattt cacggaattc gatatcttca acagtcaagc
    26101 cttttccacg gacaaatcct tgagctgctt tggtaaagtt tccatcacta tccaaggcaa
    26161 ttttctttgc tggtcccttg aaatcttctg tcaaatcaga ctgtttgtct gataaaccag
    26221 tcacacgaac agccaaacga cgtggtgttg agaaggtttg aatggcttca aaagacaggc
    26281 ggttttcctt gaggaaggct gccatttttt cgcctagttg tttttcactt ggtgtgacaa
    26341 cataggctgg taattcttca agaccgagtt ctactaataa gttttttgtc atgttttttc
    26401 ctttacattt tcttcaatct tttttgatat gcaccttagg tactggggac gtcgctaact
    26461 aactctgtga gtctgtatgg aaatccaatg ctaaatttat caagatttcc aacaatctca
    26521 tcaaagtgga tttagctgac tgatttttga acctaaggtt tcaaaaatcc ccacataaca
    26581 gtacggcggt gcatatccct ctagcaagtc ttcgacttgc ctctaacgat tttagagtac
    26641 agtattactc actattctgc gtcttctgct aaaagtttaa ctcgtgtttc ttcatccaaa
    26701 agtgggtaac ctaggcgttt gcgttctgca acaaaggttt tggctacaac acgggccaag
    26761 ttacggatac gagcgatata gcctgcacgc tctgttacag atacggcacc acgcgcgtca
    26821 agcagattaa aggtatgtga acatttgaga acatagtcat aggcagggtg taccaagcct
    26881 tcttctaatg cacgaccagc ttctttttca aacttatcaa agttttcaag caaaatttct
    26941 tggtccgaaa tttcaaatga atattttgag tgctcatact caggctggat aaagatttct
    27001 ccgtatttta caccatcagc ccactcgata tcatagacag agtctacttc ttgaatgtaa
    27061 gaagccaagc gctccaaacc ataggtaact tccgcagtca cagggccagt tgccaatcca
    27121 ccgacttgtt ggaaataagt gaactgagtg atttccattc cgtcaagcca aacttcccaa
    27181 ccaagaccag ctgaaccagt tgatgggttt tcccagttgt cctcaacaaa acgaatatcg
    27241 tgctccaaag gattgattcc caatttttcc aaagactcaa ggtaaagttc ttggatattt
    27301 gatggagaag gcttcatgac cacctggaat tggtggtgtt ggtagagacg gttagggttt
    27361 tccccataac gaccgtcagc aggacgacgt gatggctcta cataagctgc attccatggc
    27421 tcaggtccga tagcacgaag gaaagtgtaa ggactcattg tccccgcacc tttttcattg
    27481 tcataagcct gcataagcat acaaccttgg tcattccaaa attgttgcaa agtcaaaata
    27541 atttcttgaa atgttaattt cttagacatt gtttactcct taataaaaaa tgatttcttg
    27601 cgacacgagt ct
//
LOCUS       DAVBOU010000028        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBOU010000028 DAVBOU010000000
VERSION     DAVBOU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.028"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ879_001280"
     CDS             complement(15..311)
                     /locus_tag="VQ879_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143430.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ879_001281"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ879_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3143431.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ879_001282"
     CDS             complement(3584..4810)
                     /locus_tag="VQ879_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3143432.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ879_001283"
     CDS             complement(4853..5545)
                     /locus_tag="VQ879_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3143433.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ879_001284"
     CDS             complement(5731..7482)
                     /locus_tag="VQ879_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143434.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ879_001285"
     CDS             complement(7472..9217)
                     /locus_tag="VQ879_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3143435.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMLSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ879_001286"
     CDS             complement(9423..9719)
                     /locus_tag="VQ879_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3143436.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ879_001287"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ879_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ879_001288"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ879_001288"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3143437.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ879_001289"
     CDS             11300..11443
                     /locus_tag="VQ879_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3143438.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ879_001290"
     CDS             11443..11682
                     /locus_tag="VQ879_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3143439.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ879_001291"
     CDS             12560..13141
                     /locus_tag="VQ879_001291"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3143440.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ879_001292"
     CDS             13141..14403
                     /locus_tag="VQ879_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3143441.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ879_001293"
     CDS             complement(14490..15356)
                     /locus_tag="VQ879_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3143442.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ879_001294"
     CDS             complement(15343..16113)
                     /locus_tag="VQ879_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3143443.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ879_001295"
     CDS             complement(16139..16993)
                     /locus_tag="VQ879_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3143444.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ879_001296"
     CDS             complement(17150..17554)
                     /locus_tag="VQ879_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3143445.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ879_001297"
     CDS             complement(17624..19105)
                     /locus_tag="VQ879_001297"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3143446.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ879_001298"
     CDS             complement(19124..20302)
                     /locus_tag="VQ879_001298"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3143447.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ879_001299"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ879_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3143448.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ879_001300"
     CDS             complement(21519..22556)
                     /locus_tag="VQ879_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3143449.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ879_001301"
     CDS             complement(22557..22910)
                     /locus_tag="VQ879_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3143450.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ879_001302"
     CDS             complement(23154..24044)
                     /locus_tag="VQ879_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3143451.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ879_001303"
     CDS             24177..24713
                     /locus_tag="VQ879_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3143452.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ879_001304"
     CDS             complement(24879..25685)
                     /locus_tag="VQ879_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3143453.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7805 a         5737 c         4613 g         7859 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa atgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtagt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagaca
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaacgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgagc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBOU010000029        25830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBOU010000029 DAVBOU010000000
VERSION     DAVBOU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.029"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ879_001305"
     CDS             59..772
                     /locus_tag="VQ879_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3143454.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ879_001306"
     CDS             786..1433
                     /locus_tag="VQ879_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143455.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ879_001307"
     CDS             1571..2224
                     /locus_tag="VQ879_001307"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3143456.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ879_001308"
     CDS             2234..2698
                     /locus_tag="VQ879_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3143457.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ879_001309"
     CDS             2711..3979
                     /locus_tag="VQ879_001309"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3143458.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ879_001310"
     CDS             3993..4253
                     /locus_tag="VQ879_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143459.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ879_001311"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ879_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3143460.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ879_001312"
     CDS             5779..6747
                     /locus_tag="VQ879_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3143461.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ879_001313"
     CDS             6763..7755
                     /locus_tag="VQ879_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3143462.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ879_001314"
     CDS             7973..9016
                     /locus_tag="VQ879_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3143463.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ879_001315"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ879_001315"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3143464.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ879_001316"
     CDS             10829..11818
                     /locus_tag="VQ879_001316"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3143465.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ879_001317"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ879_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3143466.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ879_001318"
     CDS             complement(13455..15005)
                     /locus_tag="VQ879_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3143467.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ879_001319"
     CDS             complement(15021..15800)
                     /locus_tag="VQ879_001319"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3143468.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ879_001320"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ879_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3143469.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16720..18228)
                     /locus_tag="VQ879_001321"
     CDS             complement(16720..18228)
                     /locus_tag="VQ879_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3143470.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18313..18546)
                     /locus_tag="VQ879_001322"
     CDS             complement(18313..18546)
                     /locus_tag="VQ879_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3143471.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDGLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18816..19040)
                     /locus_tag="VQ879_001323"
     CDS             complement(18816..19040)
                     /locus_tag="VQ879_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143472.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19144..20973)
                     /locus_tag="VQ879_001324"
     CDS             complement(19144..20973)
                     /locus_tag="VQ879_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3143473.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKVFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ879_001325"
     CDS             complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ879_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3143474.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21330..21686)
                     /locus_tag="VQ879_001326"
     CDS             complement(21330..21686)
                     /locus_tag="VQ879_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143475.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21982..22272)
                     /locus_tag="VQ879_001327"
     CDS             complement(21982..22272)
                     /locus_tag="VQ879_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143476.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22262..22627)
                     /locus_tag="VQ879_001328"
     CDS             complement(22262..22627)
                     /locus_tag="VQ879_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143477.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22624..24039)
                     /locus_tag="VQ879_001329"
     CDS             complement(22624..24039)
                     /locus_tag="VQ879_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3143478.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24042..24725)
                     /locus_tag="VQ879_001330"
     CDS             complement(24042..24725)
                     /locus_tag="VQ879_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143479.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24953..25723)
                     /locus_tag="VQ879_001331"
     CDS             complement(24953..25723)
                     /locus_tag="VQ879_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3143480.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEE
                     LYSINPNQARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
     gene            complement(25723..>25830)
                     /locus_tag="VQ879_001332"
     CDS             complement(25723..>25830)
                     /locus_tag="VQ879_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3143481.1"
                     /translation="TNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT         7820 a         4828 c         4813 g         8369 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agtttttttc ctttcatagc aagggtttag agcccctatt
    16681 ttattttact attgtctaaa caccaagcga acaccaaaac taccatgcaa tggaaaaacc
    16741 tctgatttga ttctcacttg atttcacaat ctttatatca aactgtgggt ggtatttgac
    16801 aatatctttt ttgattttta atagtaaatt cgaaataata tttttaggtg agtaacgtgg
    16861 actaagatgt aacaagtctt tgaactcatc gacactaaat tctactttat tgctattatc
    16921 actagtttca atgaattttt caattattct ggaatattta caggtataac ttttcaattc
    16981 ttcaaaatgg aaattgtgat tttctacaaa ttgatttaag gcttttacag tattttcttg
    17041 tgaacgattt atattatgtg tatagcccat tgttgtctca aagttagcgt gtcctactct
    17101 agtcataata tctttcactg ctatgtgcat ctcattactt tgaaggtaac taatatgcat
    17161 atgcctaaac gaatggggag taacatgttt tacccactta aaaccatagt cacttaaaca
    17221 atttgtcaat aattttcctt ctattcgttt caaaatttga cgaaaagtgc ttgatgttat
    17281 tggagagccg tattctgttc taaatacact ttcagaatgt gtaaaagcag gacagggatg
    17341 tttctccata taagcatcaa actctttatt tctctgtatt gtccttttaa tagcttcgct
    17401 tgcagcttca ggcaaagcta cttctctaat tgaattgagt gttttagttg tatcaaagtg
    17461 aaattgttca acttttaaac aatgatattg aagtgcctta tcaatatgca agattccttt
    17521 ttcaaaatca atatctgatg gtaaaaatgc tgcttcacta attcgaatac ctgtaagcaa
    17581 caatactata gcaagatcat aatagtttgc atttctgcat tggcttaata catcaaaaaa
    17641 tgcgtgtaat tcatggattt ctagaaattt agaatcatgt ctttcttttg ctttacgcct
    17701 tttctctagt gaaatatcta gttttaccgc agtcatagga gagaacttaa tgacattata
    17761 taacacacca tgattaaaaa tcttattaca agtacttttt atatgagtca ttgttgaagg
    17821 tgatgcatca tatatttcta aatatttatt gagacttttt ttcatcagaa gtggagtaat
    17881 cctgtctaat aaaaaatcat ctcctataat tttcccaaga cgcttcatca ccagtagttc
    17941 tctctgaatt gtttgtggtt taacagagac acaccaagtc tgaaaccaat tttcttttaa
    18001 ctctccaaat gttgtaatca gttcagggct aaactgactt tcaaatgaag tagttagtct
    18061 atctatctta tcaagaacct ctctttcagc ttgtttcctc gccctactag tattcttagt
    18121 ataacttaca gttactgatt tccactttcc tgttagtgga tctttgtact tttcaaccac
    18181 ttgatataag ggttgccctt ttgaatttgt tttagttaca taatacataa tttaattcct
    18241 cttaactctt aaaaagaaat aaatcattgt tgtatagaat aaataactac cctatattat
    18301 accatgactt ccttattttg tccgcttttg cttccatctt aagaaacttt caaatccttc
    18361 tagattaatg aaaacaagtt tatgggttgg gttaattaca tacatggaaa atgttctgtt
    18421 ttctcgcatt tctttaatcc atctgttcaa tgtatattga tttaaaccat cccatctttt
    18481 tagaattcct ttcttatcgg cccattctgc aatggaattt tcgacagata tatattttat
    18541 attcatgtca tcatccttcc taaaaaatat tttcacctcc atggcatgac tgatgaagtc
    18601 atcataagaa tttcacttgc tgctctttta cggtggcagc ctgaacggtc agaagtatca
    18661 ttgtatatca tttgtatcat ggcatataaa gtatcgctct attttattga tggttttaat
    18721 atcgctctta tcatggcgag ccattcaaaa ctgctccaca aatgaggaaa gtaccatttt
    18781 ggactattca attgtcaatg tgctttctta acctactact ttttggagta atggtcttct
    18841 ttattatcca ctcgacctac aaggtagtct agactcacct tataaaaatc tgcaagtttg
    18901 ataaggtcat ttatagagat tagcctgcta ccagcttcca ttttagaata agatgatctt
    18961 gtacaattca aaacgatttt cgcaatatat tcttgtgtca aatcatcatc ttcacgtaaa
    19021 tctctaatcc ttttcaacat ttgttgtctc ctaaaacaag tataatatag ttattttctt
    19081 atttttaaat atgtgacaaa ttggcacatg aaactattct atatatactt tttaggaaac
    19141 tgtttactct aaatgtatct cattttcctt aatagatttc gtattttgtt ttttcttata
    19201 tttctttatt gttttattaa acatttcaaa taaatttatt gcttctctat gttgttcctt
    19261 cagtgtttca atctttcctt tatatatgta taaatccttc tctattgtat ctactgaact
    19321 tttaccttga atactatttt ctaaattgct agaactattt gtcgcatcat tcaacaatac
    19381 ttcttctaaa ttactcaaat catcaatttt attttgaacg tggtcaatca tattctctag
    19441 atatgatatt tgggcaatga aatccttggt tatatcttca aaagcattct gactattttc
    19501 tgcagataca agaaaatcta attgttctat tttttcttta attttgctaa gaggaattct
    19561 tctatacata tactgcggtt catactgaag attaaattgc ctaatcaaag ttttaccttt
    19621 cataaagcga tttttttctg ttgaatcttt atgatataca tagtaagaac tagtttctct
    19681 gagaaatact ttaacttttt cttcttccat attgatttga atatttggta caaaaataag
    19741 tccttcttgt cggataccaa actgtacctt aatgtaaatt ccatcgtcta ctacttcttc
    19801 tatttgatta agattcaact ctacttcaaa ctcatgaact gcatccctat ttctcttgaa
    19861 atcttgatag gatttccata ccacctcttc tgtcggcaac tctttttctt taattagctt
    19921 ttcttcattg taaagttcaa ctaaattttt attatctaag acaacagttt catttttgtt
    19981 attaaaatag ttttgaaaat aactaacact ataccgatta gcttttacca attcctgctc
    20041 tgaaatctta atctcatcaa attcaaattg aacatgtttt tctttcggaa ttatttttaa
    20101 tccaaaaaat tctgctcgtt gaatcaattc attcatattc ttcattttcg gaagtaaaaa
    20161 ttctaagata tttatgattt ccctttgaac aaactttttc ttaaaataag tttcattata
    20221 aggttgtttt ctactcaatt tactatcacg tacgacttgt ttcatatttg aatcagtcat
    20281 aaaaaaagta acatgcttgt gtctaaaatc aattttcaaa tgtaaagctt ttgctttttt
    20341 cttgaaatct tcaaaatttt tcgagttctc gattagaaaa tatactcgtt gttttatttc
    20401 atatttgtaa tttgttttgc gataaacttc atactgacga tgcgaataac gattttctat
    20461 aatttttgcc cctgcaattt ttgaaagacg atcagaaacc attcgtagat tacgttctga
    20521 cttataatcc catagaaact ttttatcaga attctgatca attgaattta ggatgatgtg
    20581 attgtggata tgatctttat ccatatgagt tgctacgata aaacgaaatc tacctcctgt
    20641 caactcttta actgtctcat aaccaatctg attgatttgt tcgggagtga ggtggtcatc
    20701 tggagaaaag gactgaatga tgtgatgaga atgaattttt cgttgattta cttctcgcct
    20761 atcatgacga aattcataaa gagtatcatt acttaaaaaa ttatcattgt acatcttcac
    20821 tagttcttca taactaggaa aatctaaata atttctcatt ccaaaatctg aaactagtgt
    20881 taggtttttt gttttacttg gattcaaaat atatttgatt agtttactac gataattttt
    20941 tccatgaatc gcaaagtgtt tagtgatgac cataaaattt cctcaatttt tcagattgaa
    21001 taagaaaatc tttctccact tctactatta actcttctat accttttctc aactcattta
    21061 attcaacttc cgttattaaa ttagaataat ttatgctcct agctatttga ttaatattat
    21121 ttcctattcg ttttaattca aaaatcaaat cttgataact atttgtatca atggtgataa
    21181 aattcatacc aggatctagt agagttcgtc tagcatattc tgagaacgat aagcagttac
    21241 tttttgagat attttcattc aatttgacta attctaggtc agataaaaag acctttttta
    21301 aatttgttct atatcggtgc tccactctac tacctcatgt atttgttacg aaaatcttca
    21361 ctaagaggac ctgttttttc tacctcttta attaattcct gaatacaagt taacaaaata
    21421 gaaacatgtt cgtgagtaac ctgatgattt gttttagcaa ttatgaatac ttcatgaaca
    21481 tcacggctaa tttgttccaa cttttgtttt ttccaaaggt tgaaccattt ttccatctgt
    21541 ttttgtccat cagataatag taagctttta cggagaaaat cagaaaaatt atcctctcct
    21601 ttctctctca ttaaatctag tatttgtttt tcttccgttt ctgttaagcg aaattgtttc
    21661 cgaatactac gtatatctct tttcatatga tttatcctct ctcatagata cttgtactga
    21721 caatgtaagc ttacagacac tgtcagtacg ttttacaaaa tagattcaac atttttgtaa
    21781 ggctttgcga gctcagatat tgtgtccaca atatcccaaa aatcatatcg cctgccattt
    21841 caaacctcac ggttcaaaaa acaaacgata tgacaatgtg gtggctccgc ccccaaaccc
    21901 ccaagataaa tctaaattaa aaaaagtata acaaatactt tttgataaaa ttatcacaga
    21961 aaaaagagcc ctgtcggact cttacaaatt aaaacaatgt ctctgatatt catactgtct
    22021 aataccacta ctgtctttgt tcatcttgat agaaaaaaca aagtaatgat cacgaccgtc
    22081 taaagattta cttttgttaa gtttaaaata atgtttttga gacatagcca ttgtgcgtaa
    22141 aatatcatct gtgataaatg ttaatggtat atctaaagct gaatacttgt aaaaatctga
    22201 ctcaaactgt aaataagaat ctgaaaaata atctagctgt aatttatcat catataattc
    22261 tttacgattc atgtaattcc tccccttcta tctgtatatc gagtatatct tcccatttta
    22321 atcgaagaaa accagtgtct gattttatag atataaactc ttttccaatc tctttaacaa
    22381 tacctgatac tacttttctt tgattagaaa acttaaaaac aaaagttgca gggaatacat
    22441 tcgtataaag ttgacgaaca aatagaactt tctcttccaa tgatagggaa atggagatat
    22501 cttctttatt tttttctgcc caaagagaac tggaatgttc tgataaaaag aagcccatcc
    22561 acttagccat gccacgatcc tgatatactc gggcagactc aaaaggtaaa taagaacgat
    22621 tcatcatttt agtccatcta atcctccagc tgaatgacca ccaatgagtt tgcttctagc
    22681 aattgttcta gaagcttgat ctagggcatt acctttcaat agtgaagtga atccaaattc
    22741 tgttcgaata gcatcgattg cggactggag cctttcttct ttttctattt tctcaatatc
    22801 atcaaataat gaaatcaatc caaaggattc atccactaaa ccagaatagt taaccgcaac
    22861 attcctgata gctcctgaag tatatttagt gtgaaataac tttaaaacgt agtttgtcag
    22921 tagtgctgtt tgattagttg gttcaatttt catttgagta ttgatagaac gcttttgttc
    22981 cactttagag tagcctagat gtatagaaac tactgttgct tttttaccag atcttctcaa
    23041 tctaactgca acttgttctg ccatctcacg aagtatgatc tcaatatctc tttgtttaat
    23101 ataatctttt ggtaaaactt gagagttccc tatccctttt gactttggct tataaggttt
    23161 atgaacgttg ctttcgtcaa tcccattggc atgaaaccat aactctagtc ccataatccc
    23221 aagctctttt ttaatcaagt caggattagc ctgagccaat tctttaatcg aaaagatacc
    23281 taaattatgt aatcttttct ccgtgcgatt tccaattccc cagaaatctg tcattttagg
    23341 aatagtccat actttctttt cgacatcctc ataggaccaa ttggctctca ttgtcggagt
    23401 ctttttagct tcattatcaa gtgccaactt agctaataag ggattggcat tagacatacc
    23461 taccgttgaa tagattcctg tttttctcca aatctttttt tgaatggccg ccgaaataat
    23521 atctaactta tcttttcgac taatcctttt atcaggcaca aaataattta atgaactggt
    23581 taaatcaata aatccttcat caattgaata gggataaata tcgtctggag ccgcaaattc
    23641 ttgaaaaatt ttttgaatct ccatattgac tgcaatataa gtatccattc tcggaggaac
    23701 aatcacagtt gattttgccc attcctctat ataacgaaca taatctatcg ttgtcggtaa
    23761 accttgcttt ctagcattat aataagagaa tttgcgagtc tttacatcaa aaggtaaatc
    23821 ataggaacgt ccaacgttcg actttccaaa gaccttttta aacataggag aggaagcaag
    23881 aattaaacca gcagaattat ctgcacgact cataacacaa agcgaagtct taagtgggtg
    23941 taatcctcta tctacacatt ctacacttgc gtaaaaagat ttcatatcaa taaaggcaat
    24001 gtcactttga ggttcgagac tataatcaaa ccaactcata cttagtcctc taaaggcata
    24061 aagttcccaa ctattttccc tataatgcga ggattctcat cataaggcgc aaacttatct
    24121 ggatagttcc gattgagtga aactaatcta agcccatttt cttcacgata aactttcttg
    24181 ataaaggttt gactgtccca atctatcgca tagatagccc cgtcatagtc aaatcctgtt
    24241 tgcttaataa gggctacaga accattttta taagttggtt ccatagaaac accagatacc
    24301 cacgatgcaa agtcataatc aaattgacga ttaaaataaa ctgtatcgta attaccatca
    24361 tcaaagtaag ctgttcccgt accagctgat aatttttcat aaaccttata agcaaaacgc
    24421 tcaggaattt ctacaacctt cgcattctgt ttgttcaaca attctgtagc ataatgaagt
    24481 gttgcttttt gattcttttt agttagcttg agataggttt ctactatttc aaactctgat
    24541 tcaaaatatc gagggtctac attaaaaatc tcactcaatt tgcttagatt attttgattc
    24601 ggttttgttt tacctgattc ccaattaaag tatgaagctc tactaattcc taaactagaa
    24661 gcaagttgag attgagataa gccttgactc tctctttttt cttttaattt agtaggtgaa
    24721 aacatctctt ctcctttgta agtttattaa ctaacaaaag agtaccatag cttcttgaaa
    24781 aaatcaagag tttaataaca ccctggattt aaaataatca taaactacaa gaaatcatca
    24841 ctgaagaatg ctaaaacttt tgaaaaaatt tgaagaagaa aatagagaat ataaaaaagg
    24901 atcgttattt tttaattgac gatccaatag actttatttt aaaaatctaa ctctacaaac
    24961 catttcgatt agttaaatct ttcaatcttt cttctccaga tttaagcatc tctttctcca
    25021 cttgattcca ttctccaaat agtaaatcat gaagaacggt tgctgctgaa gttgtatttt
    25081 cttttgaatc atatacacaa cttctatctc gttgataaat ttgaattctt tcaaaaatag
    25141 ctagttcttc caattgccgt gtattatcaa ctagatgatt tacaatgaaa tcatgatgtt
    25201 cttttgaagt tgcgcgtgct tgatttggat tgatagagta cagttcttcg tatcggataa
    25261 gagtactcag ataggacaat tcgggcttgg ttgcgattaa agctaattgt acttcatatc
    25321 ccttactttt caagagttgt gctgttttct ttggaacatc aatcgttcgt aaagttccct
    25381 ctatcaaaag attgtatccc aaatgactca attctgttac taaagactct accattttac
    25441 ctgcaaaatc tttggtgtat tctacactat ctttgccata ttcttgctgc agttctaaat
    25501 agcgtggatg ctgagaacga aaactatcac catctatgat aacaatattt ccttgaaatt
    25561 ctttctgttt aatccgatga attgtagttt taccggcacc actttgccct ccaagcaaaa
    25621 tcgctatagg ttgcttactg gacttttttc ctcttgtcag tgaacgaaga ttccgtgtta
    25681 gagcatgttt gaattcacta tcagtataat cttggatttc cattaggcta ccatccgttt
    25741 ttcagatatc tctaacatac gttcaattcc atccaaatag ccgctatacc tctctatttc
    25801 atcaaaagtt tctactaaat agatattcgt
//
LOCUS       DAVBOU010000030        25372 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBOU010000030 DAVBOU010000000
VERSION     DAVBOU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25372
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.030"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..218)
                     /locus_tag="VQ879_001333"
     CDS             complement(<1..218)
                     /locus_tag="VQ879_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143482.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
     gene            complement(437..736)
                     /locus_tag="VQ879_001334"
     CDS             complement(437..736)
                     /locus_tag="VQ879_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3143483.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            1206..1805
                     /locus_tag="VQ879_001335"
     CDS             1206..1805
                     /locus_tag="VQ879_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3143484.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     misc_feature    1900..1987
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            2023..2337
                     /gene="rplU"
                     /locus_tag="VQ879_001336"
     CDS             2023..2337
                     /gene="rplU"
                     /locus_tag="VQ879_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3143485.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            2353..2697
                     /locus_tag="VQ879_001337"
     CDS             2353..2697
                     /locus_tag="VQ879_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3143486.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            2714..3007
                     /gene="rpmA"
                     /locus_tag="VQ879_001338"
     CDS             2714..3007
                     /gene="rpmA"
                     /locus_tag="VQ879_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3143487.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(3318..3523)
                     /locus_tag="VQ879_001339"
                     /pseudo
     CDS             complement(3318..3523)
                     /locus_tag="VQ879_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            3960..4877
                     /locus_tag="VQ879_001340"
     CDS             3960..4877
                     /locus_tag="VQ879_001340"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3143488.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(4970..5818)
                     /locus_tag="VQ879_001341"
     CDS             complement(4970..5818)
                     /locus_tag="VQ879_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3143489.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            5960..6799
                     /locus_tag="VQ879_001342"
     CDS             5960..6799
                     /locus_tag="VQ879_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3143490.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            6906..7181
                     /locus_tag="VQ879_001343"
     CDS             6906..7181
                     /locus_tag="VQ879_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3143491.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            7712..8758
                     /gene="pheS"
                     /locus_tag="VQ879_001344"
     CDS             7712..8758
                     /gene="pheS"
                     /locus_tag="VQ879_001344"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3143492.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFVEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            8758..9267
                     /locus_tag="VQ879_001345"
     CDS             8758..9267
                     /locus_tag="VQ879_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143493.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            9344..11746
                     /locus_tag="VQ879_001346"
     CDS             9344..11746
                     /locus_tag="VQ879_001346"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3143494.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(11814..12815)
                     /locus_tag="VQ879_001347"
     CDS             complement(11814..12815)
                     /locus_tag="VQ879_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3143495.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            12971..13418
                     /locus_tag="VQ879_001348"
                     /pseudo
     CDS             12971..13418
                     /locus_tag="VQ879_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            13544..13810
                     /locus_tag="VQ879_001349"
     CDS             13544..13810
                     /locus_tag="VQ879_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143496.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            14070..16319
                     /gene="metE"
                     /locus_tag="VQ879_001350"
     CDS             14070..16319
                     /gene="metE"
                     /locus_tag="VQ879_001350"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3143497.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            16383..17249
                     /gene="metF"
                     /locus_tag="VQ879_001351"
     CDS             16383..17249
                     /gene="metF"
                     /locus_tag="VQ879_001351"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3143498.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            17808..20021
                     /gene="pnp"
                     /locus_tag="VQ879_001352"
     CDS             17808..20021
                     /gene="pnp"
                     /locus_tag="VQ879_001352"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3143499.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            20037..20654
                     /gene="cysE"
                     /locus_tag="VQ879_001353"
     CDS             20037..20654
                     /gene="cysE"
                     /locus_tag="VQ879_001353"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3143500.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            20666..21550
                     /locus_tag="VQ879_001354"
     CDS             20666..21550
                     /locus_tag="VQ879_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143501.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            21632..22975
                     /locus_tag="VQ879_001355"
     CDS             21632..22975
                     /locus_tag="VQ879_001355"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3143502.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            22968..23354
                     /locus_tag="VQ879_001356"
     CDS             22968..23354
                     /locus_tag="VQ879_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3143503.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            23358..24242
                     /locus_tag="VQ879_001357"
     CDS             23358..24242
                     /locus_tag="VQ879_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3143504.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            24379..24813
                     /locus_tag="VQ879_001358"
                     /pseudo
     CDS             24379..24813
                     /locus_tag="VQ879_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25121..25291
                     /locus_tag="VQ879_001359"
                     /pseudo
     CDS             25121..25291
                     /locus_tag="VQ879_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         7753 a         4650 c         5571 g         7398 t
ORIGIN      
        1 attctagtag gcataccagt tgtctcaagg taaggaatct tagacggttt ttgaaagtca
       61 tatttcttca tttgacttcc gcactcaggg caagatgggg cgtcgtagtc cagtttggcg
      121 atgatttcct tgtgtgtatc cttattgatg atgtctaaaa tctggatatt agggtcttta
      181 atgtctagta attttgtgat aaaatgtaat tgtcccatat gaatctttct aatgagttgt
      241 ttggtcgctt ttcattatag atcttatggg atttttttct acaataaaat aggctccata
      301 atatctatag tggatttacc cactacaaat attatagagc ccaaagtttt aggttgcttg
      361 atactatgcg ttttttataa tttttgcacc tttcttagcc tttgttatcg acaagtattg
      421 ttctagctcc ttgtttttag aatggcaatt tcccagcgaa agcacccagt tttttcttag
      481 tagtttcatc gatttgttca agagcagagt tgatggcttg aacggtcata tcagaaagag
      541 tctcaaggtc ctctgggtca acgacagctg gattgaaatc aatgctgaca actttcttat
      601 cgccagttaa ggtcgcttgg acaagatctt gagcagattt gccaacaaat tgcatagcag
      661 caagttcagc ttggctttgt tccatttgtt tttgaagttt ttgtgcttga cgcatcatgt
      721 tttgcatgtt catcataaga tttctaaagt tcctttcatc tcaaggggat aatccttgtt
      781 gttaacaagt gcctgatttt ctctcctaat tgttattagt agcatagcca tcaagcccag
      841 gtattgattt tattatacca tttttttaag acatagtctt ttattggtga gagttattta
      901 tgtcaaggag tgattagaaa taaattaaaa taatgatttt tgctaagagg ggctctattc
      961 tagtttcatg gaaatgattt tactaaaggt tcgtatgctt tgtttgcaaa catgttacct
     1021 ctatctattt ttggataaat agttgtctat tattattttt atgctaatag taaaatctaa
     1081 atggtagtct acgatttttt agaaagaaat ggtacaatat ttctaagaga aaatacaatg
     1141 ggagggaaaa tgaggttatt acctataaga aaaatatcac gtcagtctaa aaggttagca
     1201 cttttttgac attttgtgct ggatatgtgg atgcttacac ttttattgtt cgagggaata
     1261 cccttgtagc tggacaagct ggaaatgttg tctttctttc ggtagagcta atacaaaata
     1321 atgtttcgga tgttagggat aagcttttaa ccttaataac gtttataatg ggagtctttt
     1381 tattaacgat ttataaggaa aaattgagaa ttgtgaaaaa acctattctg tccttgattc
     1441 ctttagcaat cctatcaata attattggtt ttgtgccaca aactgtagat aatatctatc
     1501 tagtgcagcc cttggccttc tgtatgggac tggtgacaac tgcttttggt gaggtttcgg
     1561 gtattgccta caataatgcc tttatgacag ggaatatcaa acgaacaatg ctagcttttg
     1621 gagattattt ccgaactaag cacactcctt ttttgcgtga agggttcata tttgttagcc
     1681 tgtttagtag ttttgtcctt ggcgttgtct tttcagccta tttgacgatt ttctatcatg
     1741 aaaagaccat tcttggtgtt cctattatga tgagcatttt ttatctcagt atgctttttg
     1801 cctagtggca gaaaaaagta aaagaaaaag cttgatttta ggtgttatta cttgtaagaa
     1861 aataggagat atgctatact tgaagagttg actatgcacg atcctgtgca accgcacgaa
     1921 catcgttgct tgattattca agtttaagtg gtttgtccca cgatgctagg cgagtcttca
     1981 caaaaaatcg gggaaaccca taaaaatcat aggaggtgca taatgagcac atacgcaatt
     2041 atcaaaactg gcggaaaaca agttaaagtt gaagttggtc aagcagttta cattgaaaaa
     2101 ttgaacgttg aagctggtca agaagttact tttaacgaag ttgttcttgt tggtggtgaa
     2161 aacactgttg tcggaactcc acttgttgct ggagctactg tagttggaac tgttgaaaaa
     2221 caaggaaaac aaaagaaagt tgttacttac aagtacaaac ctaaaaaagg tagccaccgt
     2281 aaacaaggtc accgtcaacc atatacaaaa gttgtcatca acgcaattaa cgcttaattt
     2341 taaggagaac acatgataca agcagtcttt gagagagccg aagatggcga gctgaggggt
     2401 gcggaaatta ctggacacgc cgagagtggc gaatacggct tagatgtcgt gtgtgcatcg
     2461 gtttctacgc ttgccattaa ctttatcaat tctattgaga aatttgcagg ctatgaacca
     2521 atcctagaat taaacgaaga tgaaggtggc tatctgatgg ttgaaatacc aaaagatctt
     2581 ccttcacacc agagagaaat gacccagtta ttctttgaat catttttctt aggtatggca
     2641 aacttatcgg agaactattc tgagttcgtc caaaccagag ttatcacaga aaactaacac
     2701 ggaggaaaac attatgttaa aaatgactct taacaacttg caacttttcg cccacaaaaa
     2761 aggtggaggt tctacatcaa acggacgtga ttcacaagca aaacgtcttg gagctaaagc
     2821 agctgacgga caaactgtaa caggtggatc aatcctttac cgtcaacgtg gtacacacat
     2881 ctatccaggt gtaaacgttg gtcgtggtgg agacgatact ttgttcgcta aagttgaagg
     2941 cgtagtacgc tttgaacgta aaggacgcga taaaaaacaa gtttctgttt acccaatcgc
     3001 taaataaaaa ggtccattga accttttatc ccgaaccttg aaatgtaaag gtgaggaagc
     3061 tagaaacagc ttaaaataag gctttccgag ttttcggaga gcctgttttt ttgttttgat
     3121 atccatactt tttaatatgt atagtggatt gatactcttc gaaaatcaaa ttcaaaccac
     3181 gtcagtttca ccttgccgta ctcaagtaca gcctgcggct aacttcctag tttgcacttt
     3241 aattttcatt gagtatgaat ctggaataga acactgttaa aaattgatat gagtttccta
     3301 ctcgatttct tcagatttta tttcaattga ctataagaac tgctatctgg tttcaaatat
     3361 tggcttgtcg tcccttcact tgtctgaatg gtttgagccg ttccttctga taagggaaaa
     3421 gatattcttt agctgaaacg gtctgagaat ccaagctaac agatggagag aaaaatagcc
     3481 cagtctgaag cacactagat gggagttgtt ggaaagcagt catctagttt ttctttgctg
     3541 ttttggcttt tttctttgtc atcagggaaa gtgacttgct tcaaatcagg gagtttagga
     3601 aattcttcaa acatcttgcc caagttgtct cattttgtaa attttacagc cataggtgta
     3661 cctcgattct aaattctacc ttttcggcac caattagtaa tttaaagttc tcaggagtta
     3721 gttgcattgc tttttcatac ataacatagt atgacacttt atggttaccg aacaagtcta
     3781 atcactcctt gcaaaatttt gaagatgtcc tacaagtttt tgagaagaat attgcaaagt
     3841 tcatagttaa gcaacgatag aataaagtgc tttttgaaaa caggtacact tcatgtgaaa
     3901 aaaacaacat ttcagatttt ctgttccaga aatagctatc gctatgatat aattatttta
     3961 tgattattac tattcctata aaaaaccaaa aagatattgg cacaccatct gattcagtcg
     4021 ttgttctcgg ctattttgat ggcatacata aggggcatca agaattattt cgtgttgcca
     4081 acaaggctgc gagaaaggat ttattaccta tcgtcgttat gacctttaat gaatctccaa
     4141 agatcgcttt agagccttat catccggatt tgtttttgca tattttgaac cctgctgaac
     4201 gtgaaagaaa attaaagcgc gaaggtgtag aagaattata tctccttgat tttagtagtc
     4261 aattcgctag tctcactgca caagaattct ttgcaactta tatcaaggct atgaatgcca
     4321 aaattattgt tgcaggtttt gattatacat ttggttctga caaaaaaaca gcagaagatt
     4381 taaaggatta ctttgatgga gaagttatca ttgttccacc tgtagaagat gagaaaggaa
     4441 agattagttc aactcgtatc cgtcaagcta ttttagatgg aaatgtgaaa gaagcaggaa
     4501 aacttttggg ggcaccgctt ccatcaagag gtatggtggt tcatggtaat gctcgtggtc
     4561 gtataattgg ttatccgaca gcgaatttag tgcttttaga ccgtacttat atgccagcag
     4621 atggcgttta tgtcgttgat gttgagattc aaagacagaa gtatcgtgct atggctagtg
     4681 tcgggaaaaa tgtgaccttt gatggagaag aagcacgttt tgaagtcaat atttttgatt
     4741 ttaatcaaga tatttatggg gaaaccgtca tggtttattg gcttgatcgc attcgtgata
     4801 tgaccaaatt tgactcagtt gaccaattag tggatcagtt aaaggctgat gaagaagtaa
     4861 ctcggaattg gtcttaagag cttgagtaaa taaaacaaaa aagaggttgt ctgtaaccca
     4921 aaagatagat gatttagtct aacttttgag gtcacgacat tacctctttt tattcttttt
     4981 caaaggtgaa gccttctcct aggatttcat gggcttctgt aatagttata aaggcttgag
     5041 gatcgattcg atgaatcatt tccttcgttt tcacaatttc atttcttccg acaatacagt
     5101 agatgatttt caaattttct ttactatagt agccttgacc agaaataaaa gtaacacctc
     5161 ttccgaggtc atcattaatc gccttagcaa gttggtcagg acgttttgtg ataatcataa
     5221 agcctttgcc ggcatatcct ccttcaccaa tcaaatcaat aacacgagaa acaataaaat
     5281 caaacaaaag cgtgtaggaa accaatctca aatccttgaa gattaggaga atcaacatga
     5341 gaatacaaaa atctaagata aagagcagtt ttcctatgga tatatgagtg tatttgttga
     5401 gaatacgagc tagaatatca gttccaccag ttgtacctcc agcattaaaa ataattccaa
     5461 ggccaattcc caataggatt cccgctataa gggctgtgat tagtaaatca ccttgaagat
     5521 caatatgaag gggaatatgc tcaaaaaaag ctaaccagcc ggacaaagct aaggttccta
     5581 gtaaactaga atagagggat ttggctccaa agattttcca agctaggatg aaaaggggaa
     5641 tattaatcag caggttcatg agggaaacag ggattttaaa aagataaaat gtgatgaggg
     5701 taatacctgt cgcccctcct tcaaagagat gatggggaac tacaaaataa gtcagtccaa
     5761 aagcataaat agcagcacct agtaaaatgg taaaaatggg gtaaattttt ttaatcatag
     5821 gacacctctt ttcttataag ttgattatat caaattttac ggaaaatttg attgactcca
     5881 ttaggatttt taatcttttt tttgatataa ttagaagtaa ggaaaccaat ctgaatccta
     5941 aaatagaaag attgatacta tgacaaaaat taagattgta accgattcat ctgttactat
     6001 tgaacctgaa ctagtaaagc aattagatat tacaattgtt ccattatctg taatgattga
     6061 taatgttgtt tattctgatg cggatttgaa agaagaaggt aaatttcttc agttgatgca
     6121 agaaagtaag aatcttccga aaacaagtca gccacctgta ggtgtctttg ctgagatttt
     6181 tgaagaccta tgcaaagatg gtggccagat tcttgctatt catatgtccc atgctctttc
     6241 gggtacggta gaagcagcac gccaaggtgc tagcctatct actgcagatg tgactgttgt
     6301 tgatagttcc ttcactgacc aagccctgaa attccaagtt gttgaggctg cgaagttagc
     6361 tcaagaaggt aaagatatgg aggcaatttt atgtcatgta gaagaggtta aaaaccatac
     6421 agagctttat attggtgttt caactttgga aaatcttgtc aaaggtggac gaattagccg
     6481 tgtaactggc ttgttgagct ctcttctcaa tatccgtgtt gtcatgcaaa tgaaagacca
     6541 tgaattgcag ccaatggtta aaggtcgtgg aactaaaaca tttaaaaaat ggttagatga
     6601 gttgataaca tcgctttctg aacgtgctgt agcagagatt ggaatttcat attctggtag
     6661 tgatgattgg gcaaaagaga tgaaagaaag cttacaagct tatgttgaaa agccaatttc
     6721 tgttttggaa acgggttcca ttattcaaac tcacacgggt gagaacgctt gggctatttt
     6781 gatacgttac cactcctaaa aaaataaata aaatgggaag aaatagcgtt tttaacttga
     6841 cctaaaaggg attttaggat atgattatat ttgttaatta gaaattattt ggaggaatca
     6901 ttaacatggc aaacaaacaa gatttgatcg ctaaagtagc agaagctaca gaattgacta
     6961 agaaagactc agcagcagca gttgaagctg tatttgcagc agtagctgac tatcttgcag
     7021 ctggtgaaaa agttcagttg atcggttttg gtaactttga agttcgtgag cgcgcagaac
     7081 gtaaaggtcg caacccacaa actggtaaag aaatgacaat tgcagcttct aaagtaccag
     7141 cattcaaagc tggtaaagct cttaaagacg ctgttaaata atcagtcttt aaaaagccta
     7201 ttgtatcaag ctttctagct tggtcagtag gctttttaat tatgaaatct agtaataaat
     7261 agagttaaaa agttgaatgt tccgaaaata ttgtatatat agtagactga atctaaaata
     7321 gtacgaaaca attgctaaaa catttataga aattaatttt actttcccaa tcgatttgtt
     7381 ttcatcttat ttcaatccgc tataaagtta gataagaata agctaacaag cagaagtaag
     7441 ataggtcttg caagaatggt aaaaatctga taaactaagt ggtaattgaa tagaaatctg
     7501 aaagactagt agcccaaggg aagtatatca gggaggagag ccgtgactgc aagctctcta
     7561 tatgaaagct gggtgaattc acttgcgcat ggatttagaa atgaaggtct gacttgtcag
     7621 atgaaaacgg atggtaccgc gtgtcaacgc tccgagtgga gtttttggca tgtggttttc
     7681 tttttatcta cgagagactg atggaggaaa tatgtcaact attgaagaac aattaaaagc
     7741 gcttcgcgaa gaaacgctga ctagcttgaa gcagattact gctggaaatg aaaaagagat
     7801 gcaagatttg cgtgtctctg tccttggtaa aaagggttcg ctcactgaaa tcctcaaagg
     7861 gatgaaagat gtttctgctg agatgcgtcc aatcatcggg aaacacgtca atgaagctcg
     7921 tgatgtcttg acagctgctt ttgaagaaac agctaagctc ttggaagaaa agaaagtcgc
     7981 ggctcaactg gctagcgaga gtatcgatgt gacgcttcca ggtcgtccag ttgcgactgg
     8041 tcaccgtcac gttttgacac aaaccagtga agaaatcgaa gatatcttca tcggtatggg
     8101 ttatcaagtc gtggatggtt ttgaagtgga gcaagactac tataactttg aacgtatgaa
     8161 ccttccaaaa gaccacccag ctcgtgatat gcaggatact ttctatatca ctgaagaaat
     8221 cttgctccgt acccacacgt ctccagttca ggcgcgtgct atggatgccc atgatttttc
     8281 taaaggtcct ttgaagatga tctcgccagg gcgtgtcttc cgtcgcgata cggacgatgc
     8341 gacccacagt caccaattcc accaaatcga aggcttggta gttgggaaaa atatctctat
     8401 ggctgatctt caaggaacgc ttcagttgat tgtccaaaaa atgtttgttg aagagcgtca
     8461 aattcgtttg cgtccatctt acttcccatt cacagagcca tctgttgagg tggatgtttc
     8521 ttgcttcaag tgtggtggag aaggctgtaa cgtatgtaag aaaacaggtt ggatcgaaat
     8581 tatgggagcc ggtatggttc acccacgtgt ccttgaaatg agtggtatcg atgcgactgt
     8641 atactctggt tttgcctttg gtcttggaca agagcgtgta gctatgctcc gttatggaat
     8701 caacgatatc cgtggattct accaaggaga tgtccgcttc tcagaacagt ttaaataatg
     8761 attagaaaag tagaaatggc agatgttgag gtgttggcta aaattgccaa acaagccttt
     8821 cgtgaaacct ttgcgtatga taatacggaa gagcagttac aggaatactt tgaagaggct
     8881 tatagtctga aaactttgtc aactgagttg ggaaatcctg actctgaaac ctatttcatt
     8941 atgcatgagg aggagatagc tggttttctc aaagtcaact ggggaagtgc tcaaactgag
     9001 agagaattag aggacgcttt tgaaattcaa cgcctctatg tgctacaaaa attccaagga
     9061 tttggactag gtaagcaact gtttgaattc gcacttgaac ttgctacaaa aaatagtttt
     9121 tcttgggctt ggctaggtgt ttgggagcat aatacaaaag ctcaagcgtt ttataatcga
     9181 tatggttttg aaaaatttag ccaacatcat tttatggttg gtcaaaaagt agatacggat
     9241 tggttactga gaaagaaatt aaggtaagaa gaggattctt ctattgaaat gataggaaag
     9301 gaaaagaacc agtgtggcaa tggtcattct ggagaactaa attatgctta tatcttataa
     9361 atggttaaaa gaattggtgg acattgatgt gccatcacaa gagttggctg aaaaaatgtc
     9421 aactacagga atcgaggtcg aaggtgtcga atcaccagct gctggtctct caaaaattgt
     9481 cgtcggtgag gtcttgtctt gcgaagatgt gccagagact cacctccatg tttgtcaggt
     9541 taacgttggc gaagaagagc gtcagatcgt ttgtggtgcc ccaaatgtgc gtgctgggat
     9601 caaggtcatg gtggctcttc caggagctcg tatcgctgat aactacaaaa tcaaaaaagg
     9661 aaaaatccgt ggtttggagt cacttggaat gatctgttca cttggtgaat tgggaatttc
     9721 tgactcagtt gtgcctaagg aattcgcaga tggcatccaa atcttgcctg aagatgccgt
     9781 gccaggtgag gaagtctttt cttacctaga cttggatgat gaaatcatcg aactttccat
     9841 cacaccaaac cgtgcagatg ccctttctat gtgtggagtg gctcacgaag tggcagccat
     9901 ctatgacaag gcagtcaact ttaaagaatt tactctaaca gaaactaatg aagctgcggc
     9961 agatgccctt tctgtcagca ttgagacaga caaggcgcct tactatgcag ctcgtatctt
    10021 ggacaatgtg accatcgcac caagtccaca atggttgcaa aaccttctca tgaacgaagg
    10081 aatccgtccc atcaataacg tagtggacgt gaccaactac atcctgctct attttggtca
    10141 accaatgcat gcctttgact tggataactt tgaagggact gacatccgtg tgcgtgaagc
    10201 gcgtgctggt gaaaaattgg tgaccttgga cggtgaagaa cgtgacttgg acgtgaatga
    10261 cctagtcatc actgtcgcag acaagccagt agcccttgca ggtgtcatgg gtggtcaagc
    10321 aacagaaatc tctgaaaaat ctagtcgtgt tgtccttgaa gctgctgttt tcaatggcaa
    10381 atctatccgt aagacaagtg gtcgcctgaa ccttcgttct gagtcatctt ctcgctttga
    10441 aaaaggaatt aatgtggcaa cagttaatga agcccttgat gcggcagcta gcctgattgc
    10501 ggaacttgca ggtgcgacgg tgcgtaaggg catcgtttca gcgggtgagc ttgatacttc
    10561 agatgtagaa gtttcttcaa cccttgctga tgttaaccgt gtcctcggaa ctgagctgtc
    10621 ttatgctgat gtagaagacg tcttccgtcg tcttggcttt ggtctttctg gaaatgcaga
    10681 cagctttaca gtcagagtcc cacgtcgtcg ttgggatatc acaatcgaag ctgacctctt
    10741 tgaagaaatt gctcgtatct atggttatga ccgcttgcca actagtctac caaaagacga
    10801 tggtacagca ggtgaattga cagccacaca aaaactccgc cgtcaagttc gtactattgc
    10861 tgaaggagca ggtttgacag aaatcatcac ctatactcta acaactcctg aaaaagcagt
    10921 tgagtttacg gctcaaccaa gtaaccttac ggaactcatg tggccaatga ctgtggatcg
    10981 ttcagtcctc cgtcaaaata tgatttcagg tatccttgat accgttgcct acaacgtggc
    11041 tcgtaagaat aaaaacttgg ccctttacga gattggaaaa gtctttgaac aaacaggtaa
    11101 tccaaaagaa gaacttccaa atgaaatcaa cagttttgcc tttgccttga caggcttggt
    11161 tgctgaaaaa gatttccaaa cagcagcagt tccagttgat ttcttctatg ctaagggaat
    11221 ccttgaagcc ctatttactc gtttgggact ccaagtaacc tatacagcaa catctgaaat
    11281 cgctagcctt catccaggtc gtacagccgt gatttcactc ggtgaccaag ttcttggttt
    11341 ccttggccaa gtgcatccag tcactgccaa ggcttacgat attccagaaa cgtatgtggc
    11401 tgagcttaac ctttcagcta tcgaagctgc gcttcagcca gcgactccat ttgtagaaat
    11461 caccaaattc ccggcagtca gccgtgacgt tgcccttctc ctcaaggcag aagtgactca
    11521 tcaagaagtt gtagatgcta tccaagctgc cggcgtgaaa cgtttgacag atatcaaact
    11581 ctttgacgtc ttctcaggtg agaaattggg acttggtatg aagtcaatgg cttatagctt
    11641 gaccttccaa aatccagaag atagcttaac ggacgaagaa gtcgcacgct atatggaaaa
    11701 aatccaagca tcgctcgaag aaaaagtcaa tgcagaagtg cgttaaacga tagtatgata
    11761 caaattcccc ctctagttta tgaacactag aggggtgatt ttatataaaa taattaaaat
    11821 gtgatttctg taaaaataca tctatgatca gagttttgaa aacttacaat gtctaaatct
    11881 ttaacatagt agtggttttt aggcaataaa atatgatcta ttgttgcatt aaaaagtttt
    11941 ggactttggc tattccaagt tcctctttca aaaggtggca gtacatttaa tgcgtcccta
    12001 tgagagctta tttttgcaag tgctccatga cgcatagttg cattaaaatc acctgcaata
    12061 atagcctttg gatattttga agccaattga ttatgaatga tgtttaagtc ttgcttccag
    12121 atttccatta aacctggcag aggaggagca gtatgcaagg caatgatatc tggtatattt
    12181 tgttttctcg aatgtaatac aattgtcccg aaccgtgttg tatgaaaagt tttagcttct
    12241 gtatagaaac cataactttt cttgacaatc acagtcacag gagctattcc actattggta
    12301 ggtggagaag tgaaaatatc atagttggcc atagaaagtc caacttgatg aaacaatagt
    12361 ttgattctct ggttttcttg ctcacctctg atattggtag ctagttcagg gaatatagcc
    12421 atatcggcgt caaaatggct aaaaattcgc tcaatatgtt gtgcttctat ttgattagcg
    12481 acgttccaag ttactaattt taaggtttta gtcttatttg atgcagaaga aagggtttta
    12541 tctgttccga ataatagtaa tatgagcgat agtaagagca aaatgccaga gtaaaaccgt
    12601 atttgtttat ttttcttgta aaaagatagg aaaaaaaata agaaacttaa aatagcagcc
    12661 atagttgcag tagctaaggg gaaggcataa atctgtgcca agataggttg ggtagatagc
    12721 caaatgttaa gattagaaga tgggaaaaaa gaataagtta tgatagggat aacaaagaga
    12781 atgaccgaaa gggcagagag aaatgtttta atcattgtgt gagtacctca atttgcaatg
    12841 gttgctcgga gctaatgtga ctttgtgact ttacttgatt gatattcttt ttcttgtctt
    12901 cctcatagat taagtacaac ccaagtaaaa aaagtccaat ttaagattga aatgattaaa
    12961 aggcacagag atgcaagaca attatactac aaaaggtaaa catttgacaa tcgatagccg
    13021 tcgcttaatc gaaagatgga aaaaagaagg aaaatcaaat agagaagttg cctctctact
    13081 tggaaaagct cctcaaacta tccacactga aatcaagcgt gggacagtcc gaaaatgtct
    13141 tggaaaaggg cgcttcaaag aggtttattc tgccgactac gctcaacagt cttatgaaaa
    13201 caatcgcaag cgctcggtca agaaatcaag cttgaccaag gaactaaagg aaaagattct
    13261 ccactataca taaccaaaaa ttttcgcctg aaatgatggt tatggctaaa ggggttaacg
    13321 tgggaatttc aaccatttac tattggattc atcgtggaaa attggggtta agcaagcagg
    13381 atctgcttta tcctagaaaa ggaaaatcgc ttaagaaata ggctagcacc aactttaaac
    13441 ccgctggtca atctatcgaa tcataattcg ctcatttttt taaaaataca tagacgtaaa
    13501 agaaagaggg ttaagtgatg aagaatagtg ctattgggag taattggaag gatgtccatc
    13561 tgagctcttt agcaaggagg aaatccttga aagtgatatg cgagtagcta tcatgagcga
    13621 gttgattgaa gccagaaata agcaaggaat cagtcagaaa aagctagagg aactcagtgg
    13681 agtgagtcag cctgttatag ctaggatgga gacaggtaag actagtccac agttggacac
    13741 agtcttaaaa gtcctagcta gtctaggaaa gatactagca gtcgtccgac ttgaacaggg
    13801 gaaaagttga ctagaatcag ttatagtctt ttctaataac aagccatagt cacttataag
    13861 aattactaat aacgcgtttg agcattctaa ctaaaataca gctaaaaaca agttataaaa
    13921 gggatttgag gcatgtgtct caagtctttt tcttttgtct aaaatagagg tatagtttca
    13981 aactatatca aagcctaatt ttttacaatt atacagatgc tttcttttct gttaagatag
    14041 tttcaacaac aaattttgga ggacacatca tgtcaactac aatcatcggt ttccctcgtt
    14101 tgggcgaatt ccgtgaatta aaatttacaa ctgaaaaata ctttagaaaa gaaatctcag
    14161 aagaagaact tttagcagca gcaaaagact tgcgtgctaa acactggaac attgtcaaag
    14221 aaaaaggcat cactgaaatt ccatcaaatg acttttctca ctatgataac ttcctagatg
    14281 cggctttcct tttcaacgtg gtgcctgcat ccgttcaaaa cttggacttg tctgaccttg
    14341 agcgctactt cgctttggga cgtggttacc agggagaaaa aggggacgtt cgcgcccttc
    14401 caatgaagaa atggttcaac actaactacc actacatcgt tcctaaattt gaaaaagaca
    14461 ctcaagtaaa attggctggt cacaagattt tcgatgagtt ccaagaagca aaagaacttg
    14521 gattgaacac tcgtcctgtt cttgtaggtc cattcacttt ccttcaattg tcagactttg
    14581 aagaaggcgt gaaagcagac gacttcgtag atagcttagt ggctgcttac caagaagttt
    14641 ttgctaaatt ggctgaactt ggtgcgactc gcatccaatt ggatgaagcg gctcttgtaa
    14701 aagacttgac agctgaagaa aaagctctct tcttgaacct ttacaacaaa ctcttggctg
    14761 acaaaaaagg tcttgaagtc ttgcttcaaa cttatttcgg tgatgttcgt gacgtatacg
    14821 ctgaccttgt aaacttgcca gtagatgcta tcggtcttga ctttgttgaa ggtaagaaaa
    14881 ctcttgaact cgttaaaggt ggcttcccag ctgacaagac tctctatgta ggtattgtca
    14941 atggtaaaaa catctggcgc aacaactacg aaaagagctt ggctgttctt gagcaaatcc
    15001 cagctgaaaa catcgttttg acaagctctt gctcacttct tcatgtgcca tttacaactg
    15061 ctaatgaaga atttgaacca gcactcttga accactttgc ctttgcagtt gaaaaattgg
    15121 atgaaatccg tgacttggat gctatccgca atggtcaagg ttcagaagct cttgcagcca
    15181 acaaagaact ctttgcgact gagcgtgttg gtgaaaatgc tgaacttcgt gcgcgtatcg
    15241 ctggcttgac agacgcagac tacactcgtt tgccagcctt tgcagaacgt gaagctatcc
    15301 aagaagaagc tttcaaactt ccagctcttc caacaacaac gattggttca ttccctcaaa
    15361 caaaagaagt tcgtgccaaa cgtttggctt accgtaaagg tgaattgtct caaaaagagt
    15421 acgatgcttt ccttgctgaa acgattgacg aatggatcaa gtggcaagaa gatattgact
    15481 ttgatgtcct tgttcacggt gaatttgagc gtaatgacat ggttgagtac ttcggtcaaa
    15541 acttgtcagg atacttcttc tctaaaaatg gatgggtaca atcatacggt atgcgtgggg
    15601 taaaaccacc aatcatctgg ggtgatgtca ctcgtcttaa ccctatcact gttaaatggt
    15661 ctagctatgc acaaagtcgt acaaacaaac ctgttaaagg tatgttgact ggacctgtta
    15721 ccatccttaa ctggtcattc ccacgtgaag acatctctat caaggattct actcttcaaa
    15781 tcgcccttgc tatcaaggat gaagtgcttg accttgaagc tgctggtgtg aaaatcatcc
    15841 aaattgatga ggctgctctt cgtgaaaaat tgccactccg tcgtagtgac tggtacgaag
    15901 attaccttga ctgggcaatt cctgccttcc gcttggtaca ctcaacagta gcgtcagaca
    15961 cacaaatcca cactcacatg tgttactcag aatttacaga tatcatccca gctatcgata
    16021 acatggatgc agacgttatt tcctttgaag ccagccgttc aaaccttgaa atcttggacg
    16081 aactcaaagc gaaaaacttc caaacagaag tgggacctgg ggtttacgat atccactcac
    16141 ctcgtgtacc aaacgaaggc gaaatcgaca acacaatcga agccatcctt gctaaagtgc
    16201 caagcaagaa agtttggatc aaccctgact gtggtttgaa aacacgtggt atcccagaaa
    16261 caaaagaaag cttgatccgc cttgttgaag cagctaaagc tgcgcgtgag aaattgtaag
    16321 attggatttc tctccataca gtggttgttc aaaaagaaat caactagaaa aggttattac
    16381 atatgtcacg ccaaacaccg tcactctcat ttgaagtgtt ccctccaaac ccagccgtgg
    16441 gtaatggtaa cattatttca gccttgcagg atatgcagga gttggctccc cattttatca
    16501 gtgtaactgc cagcaataat aaatttaata tcaaggaaac gacggttcgt ttggctgact
    16561 ttatccaaaa tgacttggcg attccgacca ttgcccactt gccagctatt tatctaacta
    16621 aggacaaggt tgctgaaact attgttgact tggacaaagt tggggttcag aaaatcttgg
    16681 ctcttcgtgg ggatattatt ccagacgtag aaccacaaaa ggatttccgc tatgcaaccg
    16741 acttgattga gtttatcaag gaacaagccc ctcactttga tattattgga gcttgctatc
    16801 cagaagagca tccagattcg ccaaatcaga tttcagatat tcaaaatctt aagaagaaag
    16861 tggatgcagg ctgttcgagc ctcgtaactc agctcttctt tgacaatgag cgcttctatg
    16921 attttcagga caagtgtatc ttggctggga ttgatgttcc cattcatgca ggaattatgc
    16981 caattctgaa tcgaaatcag gctctccgac tcttgaagac ttgtgagaat atccatcttc
    17041 cacgcaaatt taaagccatc ttagacaagt atgagcatga ccctgagtcg ctcagagcag
    17101 caggacttgc ctatgcagtg gaccaaatcg tggacttggt aactcaggat gttgccggtg
    17161 tgcatctcta tacgatgaat aatgctgata cagcaaaata catccatcaa gcaacccatg
    17221 ccttgtttaa tcaccagtct ctaggataat aaaagcaaac cattcttctc aggtgagggg
    17281 aatggttcct ttttaatggt aaagacctca ctttttaaga aaaatatgat aaaataaatt
    17341 ctgtacgtac ttgatacaaa gatgaaggta ttaaataata caatgcattt aaactgtaag
    17401 atttaacgac acgagtgagt caaatcgatg ttatttgacg agagagttag taaagcattt
    17461 agctaatcgc ccgatagcga ttagcgtgaa agctttagat actttagtat taaacctttc
    17521 taatgatgta tcttgaaaac tgaacttgcc tacaactctg tggaaaaaga taaatctccc
    17581 taggagtagt cgctccgtcg ttcgatttcc tatcttcctt tgagttgctt gacggcttgg
    17641 tatcttgagt aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt
    17701 catcgaagac ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga
    17761 tctttgtagg caaggcgtat aatttcatca atcaaaaggg gattaaaatg gcaaaacaag
    17821 tgtttcaaac gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc
    17881 aagcaaatgg atctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta
    17941 tgtctaagaa aatggcaact ggggatttct tcccactcca agtcaactac gaagaaaaaa
    18001 tgtatgcggc tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag
    18061 atgcgacctt gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt
    18121 tccgtaatga agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac
    18181 caatggctgc tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg
    18241 gaccaattgc tggggtacaa gtgggatatg tagatggcca aatcatcatc aacccaagtc
    18301 aagaacaagc agagcaatct cttcttgaat tgacagtagc tggaaccaag cacgctatca
    18361 acatggtaga gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta
    18421 aagggcacga agctgtcaaa gaattgatta ccttccaaga agaaatcgtt gctgctgtcg
    18481 gtaaagaaaa agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca
    18541 ttgcagccta caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg
    18601 aagctgcaac tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcga
    18661 accacgaaga atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac
    18721 acgcagaagt gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg
    18781 atgaaatccg tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc
    18841 tctttactcg tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa
    18901 ctcaaatcat tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact
    18961 tccctcaata ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg
    19021 gtcacggtgc tcttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc
    19081 catacgctat ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt
    19141 ctatctgtgc gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag
    19201 ctggtattgc tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc
    19261 aaggtttgga agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga
    19321 ttacagccct tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg
    19381 ctcttgctca agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc
    19441 cagaagttcg tccagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg
    19501 tggacaagat taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg
    19561 aaacaggtgt taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc
    19621 aagatgctat taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg
    19681 atgaagttta ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct
    19741 ttgataagac agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg
    19801 tagaggattt ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa
    19861 aaggccgtat cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg
    19921 atgaaaaagg tgaaaagtct gagcgccctc accgcccacg tcatcaaaag gatcacaaac
    19981 ctaagaaaga atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg
    20041 ggtggtggcg cgaaaccatt gatattgtaa aagaaaatga tccagcggcc cgcaccactt
    20101 tggaggtttt gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt
    20161 ttctctggaa gcacggcttc aaactattag ctcgtatgta cagtcagttt tggcgctttt
    20221 ggactcagat tgagattcat ccaggagccc agattgattc aggtgttttt attgaccatg
    20281 gttctggtct ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg
    20341 gagtgactct cgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg
    20401 gagccctcat atcagcccat gcccaagtta tcgggcctgt ggaaattggt gaaaatgcca
    20461 aggtcggtgc tgcagcagtt gtcgtagcag atgtacctag tgacgtgacg gttgtcggta
    20521 ttccggccaa gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg
    20581 aagaaaaacg agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat
    20641 cgtctggttt gtagaggata cctatatgat tcaagcaaga aacaagttaa gccaagagga
    20701 gctatctgaa gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga
    20761 tccctatctc tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta
    20821 tgaaaaaggc gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt
    20881 aacgatactg gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag
    20941 ttttgagaga gaaatagctt ctttccccat tcggtcagtc acttttcaga cagaacgtat
    21001 ttttttagag aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac
    21061 agaaacttgg ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatcttga
    21121 agttttgtta gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt
    21181 ttcagaggaa catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga
    21241 tccagaaagt cgcttatata ttttattaaa agacggtcag gttattggga cttgtacggt
    21301 tgatttatcg actaatacga attacttcta cggtttagca atattggaac ctgaacgtgg
    21361 aaaaggctat ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga
    21421 caaggaattt cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa
    21481 aattggcttt gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc
    21541 cgaagtgtag agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt
    21601 tcttggattt cagctttcct gattatgatt tatgattaaa atctatgaca ccatgtctcg
    21661 tgatttgcga gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc
    21721 aacggtgtac aactatatcc acgtgggaaa cgcccgttcg acggtagctt ttgatacgat
    21781 tcgtcgctat tttgagtacc gtgggtataa ggttgcctat atttccaatt ttacagatgt
    21841 ggatgataag attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga
    21901 taagtacatc gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg
    21961 ccatccgcgt gtagtggagt ttatggcaga catcatccgt tttgtggaag acttgatcga
    22021 gaaaggcttt gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa
    22081 ctatgctaaa ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac
    22141 cgatgaagaa acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa
    22201 accaggtgag atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga
    22261 gtgttcagtc atgtcgacag agattttagg tgataccatt gatatccacg gtggtggagc
    22321 tgacctagag tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa
    22381 ggcttttgct aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc
    22441 taagtccttg ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt
    22501 acttcgtttc ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc
    22561 agttcgcgat gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac
    22621 aggaaacgtg gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga
    22681 tgaagatttt aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa
    22741 ctcagggaac tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg
    22801 aattgtcttt gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca
    22861 agaggcgcgt gccaatcgag actttgagac agcagaccaa atccgtgacc aattggttac
    22921 tcaaggaatt aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca
    22981 atctcattaa cgggattgcg ctagcctttg agggggatgc ggtgtattct atgtatattc
    23041 gccgtcacct catcctcaaa ggtatgacca aacccaataa actccatcaa gaagcaacca
    23101 agtatgtgtc agccaaggct caggctcgcc tgattgctct catgttggag gagcaggtcc
    23161 taacggaaaa agaagaagaa atctacaaac gtggccgcaa taccaatagc cacacaaagg
    23221 ctaaaaatgc agatgtcgtg acttatcgta tgtccacggg atttgaagcg gttatgggct
    23281 atctccatat gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa
    23341 aagtggaggg ctagaacatg agggaaaaag aactacaaga ctggtttcct gaggctcgga
    23401 tttcagacca accagtagag aaagagggct atctcacgct ccctttagct tctcagcagt
    23461 ggattttgct ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga
    23521 cccagcagga gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg
    23581 gacaggcacc gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc
    23641 agcaggaaaa tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga
    23701 cagtgctaca ggtcggatct caggattatg ttttcgtgct tcaacaagac aaatacactt
    23761 atgtaagaga tattttaagt gatacgattg aagcggttga gtatgacttt ggacttcgtc
    23821 tttctatcat gttgggtcag gtttggtctc agacgggaca tcaagcccta tcagacttaa
    23881 tcaaagctga gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata
    23941 ctttttctca gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatca
    24001 aggaatgtct acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc
    24061 tttgggaaaa tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt
    24121 ctctccaata caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga
    24181 ccgacctgac cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt
    24241 aaagaagtta atatttggag aagaggatgg ccatcttctc catttttatg tgcagagtta
    24301 tagtggcttg atgctgggaa agtacactgt gactgctaaa acattcctag aagttgcttt
    24361 gatttcccta atctatttat gtgaatttta tgttatttta ctataacagt tgttgctaag
    24421 ctaaataata gtggggaagt ttatttagac gtaagcattg aagataatca gggaggtagt
    24481 gggtataatt tcagttctgt ttcaagtagc tcacaaacag ctaaatatga aggaactggt
    24541 tataataaca attcatcatt atatataacg attgataaaa cgtctgatgc aacagctctt
    24601 ttgaaattaa agttgaataa tgttgataat caacctgcta ctgaagttcc tagttcagga
    24661 attactgtaa aattaaatgc taaagataat gctggaaact ggacaagtgc ttcgaataaa
    24721 aaagaagtaa cagtaaaaat tgtttctgct aaaccgacat atccagacaa aattttagtg
    24781 aaaaatcctg ataatataaa agatacagaa aaaaatgcca ttattgaaaa attgaaagag
    24841 gcaaataaaa atcatccagc aggagctcca acctttgcta aaggtgaagg agagcatgca
    24901 aatgatattg tagcaactta ttcagatggt acaacttatt atgtaccgtt aaatgatgtg
    24961 acaaaatatg cgaggtagtg gctgtaccac tcacttattc acctccccgt gatttgtagt
    25021 agtgataggc tttctcacta ttattataaa acaaaataaa gatcacaaca ctttttcatt
    25081 ctgtgttgtg ccttgagtga aacgaaagga atgaattata aatatgaaaa gtatagtcac
    25141 taacatagat gagcgcttgc gtactcgcct acgagtgatt atctggaagc aatggaagaa
    25201 gaaatcgaga cgattatggg gattgcttaa gttaggggtt cctaaatgga tagcagataa
    25261 ggtatctggc tggggcgagc actatcaatt atattaaaat gaaataagaa taggacgaat
    25321 cgatcaggga agtcaaatcg atttctaaca atattttaga agtagaggta ta
//
LOCUS       DAVBOU010000031        24519 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBOU010000031 DAVBOU010000000
VERSION     DAVBOU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.031"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ879_001360"
     CDS             complement(98..2356)
                     /locus_tag="VQ879_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3143505.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ879_001361"
     CDS             complement(2585..2815)
                     /locus_tag="VQ879_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3143506.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ879_001362"
     CDS             3005..3688
                     /locus_tag="VQ879_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3143507.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ879_001363"
     CDS             3688..4422
                     /locus_tag="VQ879_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3143508.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ879_001364"
     CDS             4576..5433
                     /locus_tag="VQ879_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3143509.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ879_001365"
     CDS             5575..6447
                     /locus_tag="VQ879_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3143510.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ879_001366"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ879_001366"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3143511.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ879_001367"
     CDS             7426..8637
                     /locus_tag="VQ879_001367"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3143512.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ879_001368"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ879_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ879_001369"
     CDS             9197..10006
                     /locus_tag="VQ879_001369"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3143513.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ879_001370"
     CDS             10482..11213
                     /locus_tag="VQ879_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143514.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ879_001371"
     CDS             11259..11462
                     /locus_tag="VQ879_001371"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3143515.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ879_001372"
     CDS             11487..11999
                     /locus_tag="VQ879_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3143516.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ879_001373"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ879_001373"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3143517.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ879_001374"
     CDS             complement(13390..13914)
                     /locus_tag="VQ879_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3143518.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ879_001375"
     CDS             complement(13967..14203)
                     /locus_tag="VQ879_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3143519.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ879_001376"
     CDS             complement(14271..15191)
                     /locus_tag="VQ879_001376"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3143520.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ879_001377"
     CDS             15389..15793
                     /locus_tag="VQ879_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143521.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ879_001378"
     CDS             16009..16590
                     /locus_tag="VQ879_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3143522.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ879_001379"
     CDS             16587..17864
                     /locus_tag="VQ879_001379"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3143523.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ879_001380"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ879_001380"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3143524.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ879_001381"
     CDS             18531..18920
                     /locus_tag="VQ879_001381"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3143525.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ879_001382"
     CDS             19011..20063
                     /locus_tag="VQ879_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3143526.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ879_001383"
     CDS             20207..21742
                     /locus_tag="VQ879_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143527.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ879_001384"
     CDS             21735..22793
                     /locus_tag="VQ879_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143528.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ879_001385"
     CDS             22796..23752
                     /locus_tag="VQ879_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143529.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23837..24519
                     /locus_tag="VQ879_001386"
                     /pseudo
     CDS             23837..24519
                     /locus_tag="VQ879_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7182 a         4406 c         5573 g         7358 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta aaacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaatggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact gttgaagaag
    17461 ttcaccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaagttg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt caaaacatct actggctttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggtgtcaa
    18421 ggccgccggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagctaaag acggaagtgt ttacacggga gtgaatattg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttattatga aactaactta tgatgataaa gttcagatct atgaacttag
    23881 aaaacaagga tatagcttag agaagctttc aaataaattt gggataaaca attctaatct
    23941 taggtacatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa
    24001 tcgttactat tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggcta
    24061 gactaaagat agagtttctc ttgaatacgg tctcccaagt cgtacgatac ttcttaactg
    24121 gctagcacaa tacaggaaaa acgggtatac tattgttgag aaaccaagag ggagagtacc
    24181 taaaatggga cgtaagccaa gaacgagacc tgaagagagg acagaattag aacgtcttca
    24241 agcagaaaat gagtacctga gagcggagaa tgccatccta aaaaagttaa gagaactccg
    24301 attgaaggag gaaaaagaga aagaagaaag atagaaattg ttcaagaatt aatgactgag
    24361 ttttcgttag atcttcttct aaaagccatt aaactagctc gttggaccta ctactatcac
    24421 ttgaaacagt tagacaaacc agataaggac caagagctta aagctgaaat tcaattcatt
    24481 tttatcgaac acaagggaaa ttatacttat cgccgggtt
//
LOCUS       DAVBOU010000032        23094 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBOU010000032 DAVBOU010000000
VERSION     DAVBOU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.032"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..93)
                     /locus_tag="VQ879_001387"
     CDS             complement(<1..93)
                     /locus_tag="VQ879_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3143530.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAV"
     gene            complement(101..541)
                     /locus_tag="VQ879_001388"
     CDS             complement(101..541)
                     /locus_tag="VQ879_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3143531.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(543..1580)
                     /locus_tag="VQ879_001389"
     CDS             complement(543..1580)
                     /locus_tag="VQ879_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3143532.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1678..3003)
                     /gene="brnQ"
                     /locus_tag="VQ879_001390"
     CDS             complement(1678..3003)
                     /gene="brnQ"
                     /locus_tag="VQ879_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3143533.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3174..3266)
                     /locus_tag="VQ879_001391"
     CDS             complement(3174..3266)
                     /locus_tag="VQ879_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3143534.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3309..3461)
                     /locus_tag="VQ879_001392"
     CDS             complement(3309..3461)
                     /locus_tag="VQ879_001392"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3143535.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(3621..4199)
                     /locus_tag="VQ879_001393"
     CDS             complement(3621..4199)
                     /locus_tag="VQ879_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3143536.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4253..5653)
                     /gene="pepV"
                     /locus_tag="VQ879_001394"
     CDS             complement(4253..5653)
                     /gene="pepV"
                     /locus_tag="VQ879_001394"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3143537.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5666..6271)
                     /locus_tag="VQ879_001395"
     CDS             complement(5666..6271)
                     /locus_tag="VQ879_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3143538.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6442..7242
                     /locus_tag="VQ879_001396"
     CDS             6442..7242
                     /locus_tag="VQ879_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3143539.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7424..8221)
                     /locus_tag="VQ879_001397"
     CDS             complement(7424..8221)
                     /locus_tag="VQ879_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3143540.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(8211..10055)
                     /gene="uvrC"
                     /locus_tag="VQ879_001398"
     CDS             complement(8211..10055)
                     /gene="uvrC"
                     /locus_tag="VQ879_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3143541.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(10095..10796)
                     /locus_tag="VQ879_001399"
     CDS             complement(10095..10796)
                     /locus_tag="VQ879_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3143542.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(10875..12107)
                     /gene="murN"
                     /locus_tag="VQ879_001400"
     CDS             complement(10875..12107)
                     /gene="murN"
                     /locus_tag="VQ879_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3143543.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12112..13332)
                     /gene="murM"
                     /locus_tag="VQ879_001401"
     CDS             complement(12112..13332)
                     /gene="murM"
                     /locus_tag="VQ879_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3143544.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13444..14223)
                     /locus_tag="VQ879_001402"
     CDS             complement(13444..14223)
                     /locus_tag="VQ879_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3143545.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14292..15953)
                     /locus_tag="VQ879_001403"
     CDS             complement(14292..15953)
                     /locus_tag="VQ879_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3143546.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16128..18350)
                     /gene="recJ"
                     /locus_tag="VQ879_001404"
     CDS             complement(16128..18350)
                     /gene="recJ"
                     /locus_tag="VQ879_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3143547.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18627..19385
                     /locus_tag="VQ879_001405"
     CDS             18627..19385
                     /locus_tag="VQ879_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3143548.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            19396..20190
                     /locus_tag="VQ879_001406"
     CDS             19396..20190
                     /locus_tag="VQ879_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3143549.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20203..20880
                     /locus_tag="VQ879_001407"
     CDS             20203..20880
                     /locus_tag="VQ879_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3143550.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20890..21549
                     /locus_tag="VQ879_001408"
     CDS             20890..21549
                     /locus_tag="VQ879_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3143551.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21786..22910
                     /locus_tag="VQ879_001409"
     CDS             21786..22910
                     /locus_tag="VQ879_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3143552.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
BASE COUNT         6648 a         5396 c         4225 g         6825 t
ORIGIN      
        1 tacagctaac atctcttcaa aagtggtacg ctgaacacca acaagacgct taaatcgtgc
       61 atcagttagt tgtttacttg cttcatcatt catagaacta ctataccata ttttgtttcg
      121 caggaagtct gatctcatcc ggttttgctt gacgggtttc tgcggtcatt tcttcaaaag
      181 ggacccacca gactggccca cgtccattga gaccgtgacc attcatgtca cctgttcgtc
      241 taggaaacag atgccaatga agatgggcat cgccatttcc tagcagttcg atattcattt
      301 tctcagcagc aaaggccttg gcaactgcct cttggaccac actcatttct tctagaaaac
      361 ggagtcttgt ctcctttttc aaatggtgca attccgtgac atgttccttg gctagaaaga
      421 gactatagcc tgcaaaatac tgatggtctc caatcacaag atagcctgtt tccaactctt
      481 tgacaaagta gggattttct cccttcttga tgagctcaat tctctggcaa ataaggcaca
      541 tatcaatcta ctaaattgct tctaagatag gcatcgacca ttcgttctgt tgcgaccacc
      601 gagtcaatat gagtgcgctc ataagaatga ctagactcga tacccgcacc aagaagggca
      661 tgcttgacct ctgcccctgc agacatagcc gctgaagcat ccgaaccata aaatggatag
      721 atgtccagct taaaaggaat atcttgctct ttagccaagg caaccaagtg ttgacggaag
      781 tcatagtgat aaggacctga agcatccttg acacagatag atactgtgta ctcatctgtc
      841 tgctggtcat ctcccatagc tcccatatcc acagccagat attctactac ctgagcagga
      901 atgttagaat tagcaccatg tcctacttct tcaaaaactg aaaaagcaaa atgagttgtt
      961 actggcaatt caatcttctc tttcttataa atacgaagca ggttgagcaa aatcgctgcg
     1021 ctgaccttat catccaaatg acgagacttg ataaaacctg tatcagtcac aacagttcgt
     1081 ggatcgaagc tgataaaatc accgacctca atcccaagag cacgagtttc tttttcattg
     1141 cttactttta catccaaacg cacttccata ttgtcctgcg tgcgttctgc agttcctgca
     1201 tccttgtaga catggcaaga agtttggtgg atgaggatgg ttcctgatac cttttgacct
     1261 gtgctagcca catgaacggt acagttttca ccttcaatca tgttccaagg aaaaccaccg
     1321 atacggtcca atttaagacg accatctggt ttgacagcac gaacaatagc acccagcgtg
     1381 tccacatggg cagtcacata gcgatgttgc tcatcatttt gacctttgat ggtcacattg
     1441 acaccaccct tggctgtgcg aactggctgg taaccaaaac cttctagagt cttgactaaa
     1501 taattcgaaa tttcacgagt taagcccgtt ggcgatgcga tggctgtcag ttctttgata
     1561 tattctactg tttgattcat ttcttcacct ctttcgctac ctattataac acatttatca
     1621 tcggataaaa aaagaaaatc actcctgtag acttggctac aaaagtgatt taagtgatta
     1681 ttccatttca aaaacatcgc tttcttgctt gtttggtaga accaatgaga gcaagattcc
     1741 aacaatggct ggcaccaacc atgggagaga tgccttggca aaaggaagaa cgctaacaag
     1801 atttgcaaga aactcaacct taaacgagct tcctagtacg cttgcaatgg caataactgt
     1861 aaccacagca attgtcaact gcatacctgg ttttgaaagg gcaacaaatt tgttgacaat
     1921 gacaatcata acgatagcaa tcgtgattgg gtacaagata accagtactg gaattgagta
     1981 cttgataatc gcatcaagac ccaaattggc aatagcaaat ccaatcaagg taaaggctgt
     2041 cgcataaacc ttgtagctga tttgtgggaa gcgctcatta aagaactcag ctgttgacac
     2101 aatcaaacca acagtcgttg tgaagcaggt tacggtaacc atagctgcaa ggaagagttg
     2161 agctgttgag ccaaagattt cttgagtggc ttgtgacaag atgtaaacac ctggtgttcc
     2221 acccttcatc gcttcagctg gtactgggaa atgatttcca agaaaaccta aaccaatgta
     2281 aagagcgctg aaggcaaggg caacaacgat accaataacc caaatagttg aaatgtattc
     2341 tttcttactt gaaaatccaa gttgtttcaa ggtttgaact gcgattacgc taaaggccac
     2401 tgaggcaagg gcgtccaagg tattgtaacc ttctaggaaa cctgtaccaa aggcagaagc
     2461 ttgataagca gctgaagcag cttgaggact tgttccacca tatttgatag ctcccagaac
     2521 gaccaagata acaatcaaaa ttgcaaagac tggcgttaaa atacgtccaa tgcggtctaa
     2581 gatttttgat ggattaagcg aaatcaaata ggctgccgca aaatacagaa ccgtaaatac
     2641 aatcaagcca agtcctttat ttgcatccga caaaaggggg ctaatcccta cttcgtaagc
     2701 tgttgtagca gtacgtgggg tagcaaagaa tggaccgatt gacaagtaaa gaactgagag
     2761 gtaaagagtc gcaaaccaag gcgctatctt cgttgaaatc tcgtagatat atcctttagg
     2821 atttagcgtt ccaataataa gggtcaagac ggcgatacca acgcctgaaa agacaaaacc
     2881 tgcgatggca ggaagaaaat gttctccaga tagagcacct agagaaggcg gaaaaatcaa
     2941 gttccccgca ccaaaaaata ttccaaacag gagcaaacct gttagggtac cttttttagc
     3001 cataaaaatc tccttcatat ttataaaata ctgacctagt ataccacgat taggagtctg
     3061 aaaaaagcat cacgaggcaa atattaaatg ttttcaattt tcttaaaaat aagaattatc
     3121 taaaaataaa actctcctac ccagtccaca ccaagtagga gaaatgcaaa attttaaagt
     3181 tcttcaaagg ctaacatgcc accctggaca ttgataacat tataaccttg ttctaacagg
     3241 aattggcaag cacgcgccga tctcattcca gatttgcaaa taatataatg caagcgatct
     3301 ttgtccaatt aatcataact atcagccaat tgactaagcg gtaggttgtg ggcacattct
     3361 aaatgaagag ctgcaaactc atccacttct ctcacatcca ctagagaaag ctggtcgttt
     3421 tggtaaagct ggtaaaatgc gtcaaaggct atttctttca ttctttttct tctaatactc
     3481 ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tgcgtatgtt accgacttcg
     3541 tcagttttat ctgcaacctc aaagctgtac tttgagcagc ctacgactag cttcctagtt
     3601 tgctctttga ttttcattga ctataaaatg gttttaattc tttttttcaa atctggcact
     3661 acttctgcct caaaccaagg atttttggcc atccagattt gatttcgtgg tgatgggtga
     3721 actagcggaa aataggctgg cagatagtct ttatagtgtt tcaccctctc cgttaccttc
     3781 ccactgattt tctcctgtaa atagtaggct tgggcatatt gcccaatcaa gagggttaac
     3841 tgaatatcag gcaattcctg taagagctgc ggatgccatt tttctgcaaa acctgtacga
     3901 ggcggaagat cacccgactt gccatgtcct ggaaagtaga aatccatagg caaaacagca
     3961 aaataacctg aattgtaaaa ggtatcttca tccacaccta gccagtcccg caagcggtca
     4021 ccacttttat ctttccagta aaggcctgct tcttgagttt taagtcccgg agcctgaccg
     4081 atgatattga tgcgagcagt ttttggcgct gcaaagagag gctcaatgcc acgctctgta
     4141 tagctggcat tctgtgaatc cgccatgata gcctgtttga ttctttcgat ttgagacatc
     4201 tactttccct ccaaaaagaa gtccaagcat aagatctcag acttctatcg ttttatttga
     4261 tcaattcgta aatagcttcg gcataaattg ctgctgctcg gaaaagatca tccaaggcga
     4321 taaattcatt ggcttggtgc atggtatcaa tcgagtctgg gaacatagca ccgtaggcaa
     4381 ctccgcgttc tagcaagcga ccaaaggttc caccaccgat gacttgttca tgacctttaa
     4441 ggccagtttg tttttcatag atattcaaca aggtttgcac aagtggatct tccattggca
     4501 catagtgagg cgtgtgaccg tgttcagaca ggctaacaga aacaactggc aagttttcaa
     4561 ggattgactt gatttgttct ggacttgttc cttttggata gcggatgttg agggcaatgg
     4621 tattatcagc acttgtttca tcgaagcgga agacgccggc attcatagaa agagcaccca
     4681 tcttttcatc cacatgagca atcttaagat tttcaccctc atgatcgttc aagagaattt
     4741 tacctgcgat gtcaaggtag tctttggctg gaccagcaaa gccaaactgg ctgaggaaga
     4801 gggcaaggta agttgcgcca ttgacacctg aagcaggcat agcaccgtgg gctgatttac
     4861 caatgatcgt caccttgtat ttgccagctt cttcttggag ttctcctcta agtttgtgtt
     4921 ctgcaacaaa ggcatctagt ttagcttgca agtcagccaa atcacctgaa acgactgctg
     4981 ttgctgattc tggtaccata ttttcacgta aaccacctgt aaagctgtga agacgggcag
     5041 cacctgtatt ttctcctgca aagtggaggt attccgtgat atttcctttt tcaccattga
     5101 tgattggaaa ttcagcatct ggagagaaac cgaaatctgg tttggcaagt cctacgtgct
     5161 caaagtagta gtccatgtct gcccagcctg attcttcgtc tgttccaacg atgaagcgaa
     5221 ctttcttaga agttggaaga cccaattctt tgatgatttt caaaccatag taacaagctg
     5281 ttgtaggacc cttatcgtcc gaagccccgc gcgcataaag gcgaccatct ttgatagttg
     5341 gtgtgtaagg atctgtgtcc caaccgctac cagcaggcac cacatccata tgggcaaaga
     5401 ttccgagaac ttcttctcca tcaccaaact caaaatgtcc tgcgtagtta tcgacattct
     5461 tagttgggta gccatcgcgg tctgcgattt caaggaattt ctccaaggct tttactggac
     5521 caggtccaaa tggatgctgg gcatcagcct tgctatcatc acgttctgag ttgatttcca
     5581 aaaggctaaa caagtcagcc aagaggtctt ctttgcgttt ttctacttct gctgtaaaat
     5641 caattgctgt cattttttct tctttctatc ttttctcgat gatttcatct actggcaagc
     5701 ggtagcttgg ttccaatttg tcgtctgtgt aacccactgt gatcaagagt tctgggcgga
     5761 aacggtcttc gatttccaaa acttcattaa cttttgattt gtcaaaacca aggataatat
     5821 tggaaccaat tccttggtct gtaagagcga gaaccaagtt catagcaacc aaacctgcat
     5881 tgagtgctag gtagtcgctg acttgttgtt cattgtagcg tgcaaattca gctggcaaat
     5941 ttttcatgaa gtattgaagt tgctcttcag aaaagttatt agcaccacca acacgggcaa
     6001 tcttacgagc acgtttggct aagtccgtat ctgtaaacaa ggcaatggtt acaggcgctg
     6061 atgatacctg ttcaaaattg gaaccataag ctaactttgc cagttcagca tttttctcac
     6121 gtaccaccac aaatttccaa ggctggctgt tgtgggcgct tggcgccaag gttgcaattt
     6181 cgatagccgt acgcacatct tttggatcaa caggcttatc agtaaaatgc ttagtcgcat
     6241 gacgtttttt atttaattca agaaatttca taatcgattt ccttttctaa ttctactgct
     6301 tccattctac cataatttga aagagcttgc agggattttt catgattaag tttttctatc
     6361 acagacataa aagatatata ttggtttatc aggaacattt ctgataaact agcaagtact
     6421 ttacatttga atggagacag tatgaaaaaa tttagcctat tactagctat cctaccattt
     6481 ttggttgcct gtgggaatca agctacaccc aaagagacta gcgctcaaaa gacaatcgtc
     6541 cttgctacag ctggcgacgt gccaccgttt gactacgaag acaagggcaa tctgacaggc
     6601 ttcgatatcg aagttttaaa ggcagtagat gaaaaactca gcgactacga gattcaattc
     6661 caaagaaccg cctgggagag catcttccca ggacttgatt ctggtcacta tcaggctgcg
     6721 gccaataact tgagttacac aaaagagcgt gctgaaaaat acctttactc gcttccaatt
     6781 tccaacaatc ccctcgtcct tgtcagcaac aagaaaaatc ctttgacttc tcttgaccag
     6841 atcgctggta aaacaacaca agaggatacc ggaacttcta acgctcaatt catcaataac
     6901 tggaatcaga aacacactga taatcccgct acaattaatt tttctggtga ggatattggt
     6961 aaacgaatcc tagaccttgc taacggagag tttgatttcc tagtttttga caaggtatcc
     7021 gttcaaaaga ttatcaagga ccgtggttta gacctctcag tcgttgattt accttctgca
     7081 gatagcccca gcaattatat cattttctca agcgaccaaa aagagtttaa agagcaattt
     7141 gataaagcgc tcaaagaact ctatcaagac ggaacccttg aaaaactcag caatacctat
     7201 ctaggtggtt cttacctccc agatcaatct cagttacaat aacactcttc gaaaatctct
     7261 tcaaaccacg tcagctttat ctgcaacctc aaagctgtgc tttgagcaac ctacggctag
     7321 cttcctagtt tgctctttga ttttcattga gtataagata tactaaaagc gattggacca
     7381 gccaatcgct tttttagttt gcattggcta ttttaggaaa ctcttacaaa aaatcaaaaa
     7441 aattcttcac atcctctaca tacccatgct tttctattaa gctggctaat aattccagat
     7501 tgtgcccctg atagttatcg tcacgacgca gttcttcata catttcgata aagggaagcc
     7561 ccttggactt ggccaattct aactcagctt cgtaatcata agcaacttta cgaaattgga
     7621 tattgagtaa ttccccatct tcaacttcta tcacggcata ctgggcacgg tgatttttta
     7681 acgcctccca attaaaatag ggcatgccaa tcgaccctgg attgatgatt tgttgccctt
     7741 gacttccata acgaagcaac tgcttgtgaa catgaccata aactgccacg tccgtttccg
     7801 catctagcaa gtcaccacca tagtttttgt caggtaaatt atgagagata gaaaagcgca
     7861 atccgtcaat ttctttcttt tccagcaaag gcaagcttcg tagccagaca atcgttgcag
     7921 gatccattcg ctccatcaaa tactgtgtca tacgcaagag ctgaacttcc tgtgggtctt
     7981 ctaagccata ttgcccatct aaagcctcaa ggacacgatc atcccaattg cctcgaacac
     8041 ttgctgtgat aggaaggtcc tttagcaggg cgactaagtc atttgcgcct ggaccaggaa
     8101 gaaaaatatc tcccagaagc caatattcac tggccccttg atttttagca tctgcaatca
     8161 ctgcttctag cgccgtcgca ttgccatgaa catctgataa aattgcgatt ttatggttca
     8221 ttgtggtttc cttccgtttg gtaatctact ctttcttctg ctacttgagg caaggcttct
     8281 ccctgcgggt tcaactttct ttgcacagcc tctgcaacga ctctaggtac cccaacttcg
     8341 acaatctcat ccacactggc ttccttgatt ttggtcaaag acttgaaatg cctcatgaga
     8401 ttttgcttgc gtttaggtcc cagaccatca atcccatcca attgagatga gaaagaattt
     8461 ttggagcgca gttggcggtg gaaagtgata gcaaagcggt gcacctcatc ttggatgcgt
     8521 tggaggagga aaaattcctg agaattgcga gacaagtcca ccacctcaag cggatctcca
     8581 aagagcaatt catgggtttg gtgcttatca ttcttttgca gcccagcaat tggaatatcc
     8641 aagcccagtt cctcttggat aacctgctta gcgatattga cttgaccttg ccccccatca
     8701 atcacaatca aatctggagg agtcaaagcc tcacgctgta ctcgaccata gcgtctgcga
     8761 atgacctctc tcatgctggc atagtcgtct ggtccaacaa ccgtttttat cttgtactta
     8821 cggtaatcct tcttactcgg tttaccgttg acaaagacca ccatagccga aacagggcta
     8881 gttcccatga tattagagtt atcgaaggac tcgatacgta ctggggtcgg gatttggagc
     8941 aaacgcccta gattttcaat agctccttga gtcttttcga cagatttttc tagcagattg
     9001 aacttctgct ctagactaac acgagcattt tttatggcta gattgaccag ttgttttttc
     9061 tctccacgtt gaggcttaag aatcttggaa tccaccaagg ccttgacagc ctcttcgtca
     9121 atatcctgcg gaatcagtac ctcattggga actagatgag atttttcttg atagaattgt
     9181 cctacatagg tcaaaaaatc ctcatctgga tcattgaagt aggggaagag attgacatcg
     9241 cgctcgataa gcttaccctg acggacaaag aaaacctgca cacacatcca gcccttatcc
     9301 acatagtagc caaagacatc gcgattttgc aaatctttcg ccatgacccg ttgcttggtt
     9361 cgaagcgttc caatagcctg aatcaggtca cggtattccg ccgcacgttc aaactccata
     9421 ctttgtgctg ctactgccat tttactcttg agatcatcga tgattttgtc atcctgacct
     9481 ttcagaaaat cagacacctc ctgagccata gacttgaaat aagcctcatc cttcttacag
     9541 atggtgtggg ccatacactg gccgatatgg taataaaaac agaccttaga gggcgggttg
     9601 gtacattttc gaaaagggaa aatcctatct agaagtcgct tgatttcatt ggctgccccc
     9661 acatctggat aagggccaaa ataaagacca ccgtcctttt tgacctgacg agtaatgata
     9721 agccgtggat agcgctcatt ggtgattttg atgaaaggat aggacttgtc atccttgagc
     9781 atgatattgt acttgggctt gttttccttg atcaggttga tttctaggag aagtgcctca
     9841 atattagact ccgtaacaat aaattcaaaa tccacaattt cagacaccag agcctctgtc
     9901 ttggtatcat gacttccacg aaaataggac cgtactcgat tacgcagatt tttagccttt
     9961 cctacataga taatggtgcc atttttatcc ttatgaatgt agcaaccagg gctggtcggc
    10021 aagagctcta gttttgattt aatcaagttg ttcatagttc cattatagca aaaaaagtag
    10081 ggaaagatag taccctactc actagtctca tatatttttc ggaggtttgc aacatcctct
    10141 tcctggatac cataaaagga acctgctggt tgcatgacag acttctcatc tgtatggtcc
    10201 aagccaatcg catgacctaa ctcatgttct gccgtatgga caaggcgttc ataggagtag
    10261 ccatagtatg gattggacaa ataataatga ttcaaccgca ccgttacgga caagaattgc
    10321 cctgttaaga gattagtttg actttccgcc tctcctgcca caggagtgcc tccgtcgttc
    10381 atctccgtag ccgtaatatc cgccttacta gactcagtca cgagttcaaa gttaaaagca
    10441 ccagtttgat tccagttctg gattgcttct aaataagcct cttgaaagcg tgaatccatc
    10501 tgcggatcca ggtaaatacg agcagaggcc tgtgcccacc ttccttcaga atgctggtga
    10561 ctatctgtct ggcttaactt aggcagttgc cctgttttct cccattggtc aatactttgt
    10621 tgaccaattt ttactgaccg ttctgcttgc tttagcgctc cttgaaaatc cccgttcaga
    10681 taccagagaa gtccgaaagc aagcacacat aagagcacaa ctatccaaac cagacgccaa
    10741 aacaaacgcc acacaaaaga aaagaaagcc cctatcaaac gaaaaagcca gcgcatgtct
    10801 ctccaccttt ctagcaaata agaattattt tactaaaaga agctaaaaga aatctaaata
    10861 ctgacttttt catcttaacg tcctactatt tttttgagta actggatagc tttgtatttt
    10921 aaaggcgatg gatggtaacg gaaagtaccc gctttgcgta caatatagcc attaaaattc
    10981 tgtttaaaac gcaaaacacc atcacttcca tcaaaaatcc cttgaatgcc taggaagttg
    11041 tatttaggta ttccacgttt tatgctttcc aacataacat atttttgaag cagggcaggg
    11101 gcatagaact tattaaactc agtgtaggaa ccactaaaga gataagtcgt ttcctgaggc
    11161 atataaacaa ataaactccc agctaaaaca atatcttctt ctccatattt ttcaatcaag
    11221 tctcgcgctt ctgcttttcg aacttcaaac gtttcaaatt gactagaata ttctctcagt
    11281 tgattttgtt ttttctcaga atgaggattt ttactcaaat caagtcgcaa cttgtccaag
    11341 ttttcttcta gtttactttg ttcaccttgc aatttgctca tatagtccga aaaatttaag
    11401 cttgctatga gaaactccgc ttgttctcca aaagtatcat aaaaatgctc ataatattct
    11461 aaacttttat cactatattc tctacgttca gaggtttctt ttgttatatt cttaaaaatc
    11521 gatagttctt cacgttttaa ctttttcaac cgaatgccaa aggtttcagc ctttttcacc
    11581 aagggtttac cctttttgct aaaactttta agcaaactct tttcagttaa ttcagttaaa
    11641 tctttatagt ataaccaatc tggttctcca cctgggtaac ctgttgttaa gccatcaaat
    11701 tgataaccta aatcagtcaa accttgaata atactttttt tctcagcatc tattggatta
    11761 ccttggctat caaaagtttg ataagtttca taaggtttta caagcaactc taatacacca
    11821 ttttgcttgg catattcttt taactctgca taaaaaactg gaagagcatc ttgttgggta
    11881 taaatcggcc ccgaattgag ttccatatgc agaccaccca gcatgggcaa gctataaacc
    11941 agagctgcaa cttgaatttc tccttcttgt ttcaaagcaa gataaacaat tcgagcccct
    12001 cttttttcta gcaaatcccc catctggaca gattgcataa aggaacgaga agaaacctga
    12061 tcagaataag tctgaaactc ttctttcgtg agtgttgtta gtgccatata cttactttct
    12121 atgttttttt cttaatgttt tacggaaatc aagagcaagt cttaacagag gatagagagg
    12181 atgagtgggc attgtaaatt cacccaagta ttcttcaatc gttggattaa atttttcctt
    12241 aaaatgataa agtccaccat tgagagagtt ttcaacacca cctaaatttt gccaaaccat
    12301 acctcgctca aaggcatagc gagccgtttc ataccatgtt aaaattggtg cattgtaacg
    12361 tttaaaatca tcatccatac cagcatatat attgacagag gtagtaccaa attccaaact
    12421 caaagtagcc gctaaaggaa ctctcgcttg acctacatct atatattcct gcaagaaggt
    12481 caattcctct aacaaacgtt ctttttcctt cttctgcgct tctacttttg aaattcgagt
    12541 cgactcagta aaggtctctt ccaaggctct attttttgct aactgttctt ctaattcttg
    12601 cgaacgttta gaaacatcca aggtggccaa ggtgatatag gccttgtcct taaaattatc
    12661 taacaatttt ttataatagg cttcattcct caaatgaatc tcttttcgct tctcagtttt
    12721 tttcatcaac tccgaaaatg aatctaatag ttccagtcca ccatattgaa tctcaagccc
    12781 tttgtttcgt gctgttcgaa tagcctgttt tgttgacttg gaaagtttat cttcttcaaa
    12841 attttccttg tatattttcg cctgaatacg aggttgaatg gtgtctccca tttcctccgt
    12901 ttttcctgac caccttactc ccatttgttg caaactatca ataatagcca gattttcagg
    12961 aaattctgtc ttttcctgat tgattaaact ttgagatagg caaatacttg ggtcaaaagt
    13021 cacaaaaacc gctctcttac tgcgagcata ggacttaata gactgaatga caaaattcaa
    13081 gagttcttta tccccataat ccaatatagg tcctcttggg atgtaaaaca ttttatagcc
    13141 tagcggaaga gttctaatca aaatactagc tgtcgccagt aatttttctt ccctgtaaac
    13201 accaaacttc tcatgttgcc aattagactt aacttcctcc caagcactac tttgtaatac
    13261 attggctaat tcatgttctt tgacaaactg atcatattct aatgtgggaa tgccaatttg
    13321 ataacggtac atttcctact ctctttcctc cagtatttta ttactattct actactttcg
    13381 tttgaaaagt ctagtgaaaa catattttat tttagttcta ctccccctat gctgaagttc
    13441 aaactaagtc agtctctctt ctaatttgaa atcaattggt agggttgtta aaaaaacttc
    13501 caattgtttt tcccagtagt accactcgtg agttccagcg ctatggctat aggtcacatc
    13561 aaaacctagt tttttgagat ttttcactgc gagattattg gcttcgtaca agaaatcctg
    13621 ttcgccacac cacgcccaaa gtttggtctt tttatccgat tttttagcca gactttcaag
    13681 agaataggga ctagttgtcc agtctttaat ctctccaaaa acacctctcc agtaggctgg
    13741 acttcccaga ttttgacttt caggagaaaa gttttgaaaa ctgagggcac ctgaaaagct
    13801 agctgcatga gaaaaacgat ttgtcgcaag agccagtttg aagcagccgt agcctcccat
    13861 agaaagacca gcgataaagg tcttttcacg cttgctagtc atattaggga agaagcgttt
    13921 cagaacctgt ggcaattcct ctgctagagc cgtgtagtag tcaaaaccat actgggtatc
    13981 ggtgtaccaa ccattgctgg tattgggcat aacaacgatg agattagttc ctcgaagcaa
    14041 gcgttctaca ttggtccgct taagccaact attatgattt ccagacatcc cgtgcaaaag
    14101 gtacaagacg ggaatatctt cacactctgg ttcttccact cgattggcat cagggtagag
    14161 gacattcacc ccccactcca tatccaatac ttgtgagtaa tactcgattt tcattactgc
    14221 catgattttc tccttctatt tttctataag aaaaagccga aactcgactt tctctctgtt
    14281 tatttcaacg attattttgc ttccatgact actggtaaaa tagctggacg acgcttggtt
    14341 tggtcaaaga gatacttggt caaattatct cgaaccttcc ctttaagatc tgcccagtca
    14401 aagtcatctc cttgaagata ctcttctacc gtttggttaa tcaattctga actttcatgg
    14461 agaatatcgc gactcttctt gagataaaca aatccgcgcg tatgaacacg agccctagcc
    14521 acaattttct tctcacgacg gttgactgta atagccacga tgaaaattcc atcctctgac
    14581 aagaccttac ggtcacgaag aacaacattt ccaacatcac caatggcatt cccatcaatc
    14641 aagatatctc ctgctgaaac cgatccagct ggaacaaagt ctccattctc gtaagccatg
    14701 gtcgtcccct ttttaggaat gaagatgtgt tctggcaaca tcccaactgc catggcagcc
    14761 ttagcgtgag catccaactc acgatactcc ccttggacag ggaagaggta cttaggttgc
    14821 aaaagattga tcatcagctg caaatcacgc acatttccgt gccctgatac atgtaaactt
    14881 tgggtaatca atttgacaac cccacctgcc tgataaatca tattttccac acgcgcaaca
    14941 aaggcttctt tagcaataga cggagccgta gcaatataga ccaggtcccc atccttgatt
    15001 tctacataac gatggcgacc aatcgacatc ttacgaagtc cattgatagg ttcacccata
    15061 cgacctgtct caagaataat caactcatgg tcttcaaagc gagacatatc tttaggctta
    15121 atcaagagaa tttcgttggc taaagacaac ttcttaagac gaatcgctgt gcggacgata
    15181 ttttcaatat caaatcctgt caagacgata cgtcgacctg ttttatccgc agcgtcaaaa
    15241 atctgctgaa tacgagaaag attactggaa acagctgcaa cgatgatacg accttcccag
    15301 tcagcaatag tttgggtaat ttcatcccta acttcacttt cactagccac ctgaatattg
    15361 ctgtctgcat tggccgaatc actgaggaga gccaggacgc cgtcacgacc aatctctgcc
    15421 aaacgagcaa aatcagttgc ataagattca ctagccgttt ggtcaaattt gaaatcacct
    15481 gtataaacga tgcttccttc cgatgtcttc aagacaattc ccagactctc tggaacggag
    15541 taagtcgtag ggaagaagga aaccactgtc ccaccaaaat caatctccgt attctcatca
    15601 atgacatgga aatcattaaa tttcttaacg gcatcatttc ctttgacaaa gagctttgcc
    15661 aactcaatgg tcaactcaga cccaaataca ggaactttag cctctgccaa gagataaggt
    15721 agagcaccaa tggcatccgc atgcccgtgg gtcaagaaaa ccccagcaat acggtcgcta
    15781 ttttcaaaaa ggtaatccat gtttggaatc accacatcga cccctaattg ttcattttca
    15841 ggatatttta accctacatt caaaacaaaa atggactctc caatttcagc aatgtacata
    15901 ttttttccat tctcacgcac accaccaagt gttgttaaac tgatattact catttttcct
    15961 ccaaaatctt agtttatctt gattataggg caactctacc ctcttattct aaaagttcta
    16021 atactttcag ccgaatcttt tcctaccatt ataccatttt tttgatgatt ttcaaaatga
    16081 aggtctgttt tcaaaaaaga gttgatttcc caactctttc ctaacttcta ctctttttcc
    16141 atcaaaaaat cataaatttc ttgcaccgta cccagcgcca tcatttcttg gtctttaacg
    16201 gtttgtttga gattttggta aatttgactt tctcctatct cccgctttgg cgcctcttta
    16261 ttgactgtca tcacaccatc ttttatcgtc acaaagccta gttcttcaaa tacttgaatc
    16321 atcttgacca gcaagatttg ttgaatatta agatatgcag ccaaatcttt cagcttgtag
    16381 cgaatatcaa actctgggaa ctggtaaata gtcttgtaca atttggcaaa ctgatctcta
    16441 gtcccataac ctgtcagata ataggccttg tcaatatcat ttttgaaata gacagcagag
    16501 aaatgctgtt cctgaaaaat ggtcttcagc tgagtaatat cctctggaat gttttttacg
    16561 acaatagctt cactagccgc aagatttggc agttctccag gaaaatccaa gactggaaca
    16621 ccttctggca agactgcatt ttttccacga atgttaaaaa gttgaacacc ttccactcgc
    16681 gcatccacca tcatcaactg gagggcagtt tggccattcc attggttgac agacaattta
    16741 accgctaact ctagattctt ggtttgagaa aactctgtcg cccatctgcc ttgaccaaag
    16801 gctaccactt caaaactcgc ctcacccttg gaaattttca gctttagatg ggcattacct
    16861 gcccccatag tacgagcact ttcgacctga aaattcttga tataaaaaat aggtttctga
    16921 ttatccattc caaaaggagc taaacgttca aaacttttga ccgtttccaa gctaagtgcc
    16981 tccaaatcca actcttcatc taggtttaac ttattcttgc caccagcatc tgcacctttt
    17041 tcacgaacat aatcttccaa aacctgagat aaatctgaga gttgctcaac ttccagcgtc
    17101 atacccgctg cacctgcatg acctccaaag gcgatgaaga ggtctcgatg gggatccaga
    17161 gcttcaaaaa tatcgaccgc ttccacacta cgagcactgc ccttggcacg accgtcttct
    17221 atattaagaa caatgactgt ctgtcccaat tcttccaata aacgaccagc cacgattcct
    17281 agaaccccag gattccagcc ttccttggcc aagacctgaa ccttcttctc aggatccacc
    17341 atggtcttgg cttcttcata gatagactga acgatttcct tgcgctcttc gtttttctgg
    17401 tgaatcataa gggcaatctc atgcgcttcc tcatcatcaa atccagtcaa caaatcaatg
    17461 gcaggattgg gatcatccaa gcgacccaag gcattcaaac gaggagcaat ctggaaacca
    17521 accgtttctt ctgttacttc gttggcagca atcccagcca tgtccagcat ttcttgcaga
    17581 ccaatgcgct gggtatgacc caacatttcc agaccatatt gaactaagat acgattttca
    17641 tccgtcagac tcaccatatc tgcaatagtt ccaatagcga ccaaatcaag caattccact
    17701 tgcacttctt ctaacagggc acaagccaac ttgaaagcaa ctccacaacc agccaaatat
    17761 ttaaaaggat aatccgcatc tggatgttca ggatggacaa tagcataagc atctggcagg
    17821 gtttcaggca tggaatgatg gtctgtcaca atgacatcta ctcccataga ctgagccaat
    17881 gcaatagcct catgaccagc aaccccattg tccaccgtca caatcaagga aattccttct
    17941 tgctcgataa agtatttata aacactagca ttagggccat agccatcggt aaaacgattt
    18001 ggcaggtaaa ctcggcactc cgcaccaagt tgttccaaac tttccttcac aatagaagcc
    18061 gaagtcatgc catccgcatc atagtctcca taaacgagaa tattttcccc ttcttcaata
    18121 gcctgacgaa tccgctccac tgccttgtcc atatcatgga gcagataagc atcatgtaag
    18181 tcctccaagg aaggttctaa aaacttcttc agactttctt ggtcctgaat ccctctctca
    18241 aacaataacc gagccacctc aggacccagt ccagccttct tggctatctt tgtaaaatcc
    18301 gcatcttcta cctgcagggc aaactgccat tcataagtag gtgttatcaa aaagacatcc
    18361 actctttcta agaattctat tgcttcatta taacatgatt tagacgtttt ctctatccag
    18421 attgcttttt tataacattt tatagtatat tgaaactaga atagtacacc tctacttata
    18481 aaatattgtt agaaatcgat ttgactgtcc cgatcgattt gtccttttct tatttcacta
    18541 tagtgaattt tttcagatac ggtttgacaa gaacattctt ttattgtaga attgtgttat
    18601 aaactctaac ataaaggaga tctctcatgg ctttagtaga atttaaaaac gtcgaaaaat
    18661 attacggaga ctaccacgca ctccgcaaca tcaatctccg ttttgaaaaa ggacaagttg
    18721 ttgtcctgct tggaccttct ggctctggga agtccactct tatccgtacg atcaatggtt
    18781 tagaggctgt tgacaaagga agtctcctag tcaatgggca ccaagttgct ggtgccagcc
    18841 agaaagattt ggtacctctt cgcaaggaag tcggcatggt ttttcaacat tttaaccttt
    18901 atccacacaa aacggtgtta gaaaacgtga cacttgcgcc cattaaagtt ctaggaattg
    18961 ataaaaaaga agctgaaaaa accgcccaaa aatatctgga atttgtaaat atgtgggaca
    19021 agaaagattc ctatcccgcc atactatctg gtggacaaaa acagcggatc gccatcgctc
    19081 gtggtcttgc tatgcatccg gaactcctcc tctttgatga accaacatct gctcttgatc
    19141 ctgagactat cggagatgtt ctagcagtta tgcagaaact ggcgcatgat gggatgaaca
    19201 tgatcatcgt tacccacgaa atgggctttg ctcgagaggt tgcggaccgc attatcttta
    19261 tggccgacgg agaagtttta ttagatacga cagatgtcga taactttttt gacaatccaa
    19321 gcaaacctcg tgcccaacaa ttcctcagca aaattatcaa ccacgaaagt gacaaagtca
    19381 aataaggagg cgcctatgaa aaaaaaattc tttttatcag cattattgat tagccttttc
    19441 ggccttgctg ctgccaaacc agtccaggct gatactagta tcgcagacat tcaaaaaaga
    19501 ggcgaactgg ttgtcggtgt caaacaagac gttcccaatt ttggttacaa agatcccaag
    19561 accggtactt attctggtat cgaaaccgac ttggccaaga tggtagctga tgaactcaag
    19621 gtcaagattc gctatgtgcc ggttacagca caaacccgcg gcccccttct agacaatgaa
    19681 caggtcgata tggatatcgc gacctttacc atcacggacg aacgcaaaaa actctacaac
    19741 tttaccagtc cctactacac agacgcttct ggatttttgg tcaataaatc tgccaaaatc
    19801 aaaaagattg aggacctaaa cggcaaaacc atcggagtcg cccaaggttc tatcacccaa
    19861 cgcctgatta ctgaactggg taaaaagaaa ggtctgaagt ttaaattcgt cgaacttggt
    19921 tcctacccag aattgattac ttccctgcac gctcatcgta tcgatgcctt ttccgttgac
    19981 cactctattc tatctggcta cactagtaaa cggacagcac tactagatga tagtttcaag
    20041 ccatctgact acagtattgt taccaagaaa tcaaatacag agctcaacga ctatcttgat
    20101 aacttggtta ctaaatggag caaggatggt agtttgcaga aactttatga ccgttacaag
    20161 ctcaaaccat ctagtcatac cgcagattaa ggaggatacc ctatgacaga tttatcatct
    20221 tggacagcct attttcagga ttttggacaa tttttcaatg gtttcctctt tactcttgcc
    20281 ctagcgattg gatcctttat cctcgccatg gtcttaggaa tcttctttgg tgccatgtca
    20341 accagtaaac gtccaatttt acgcatttta gctcgcatct tcgtggaatt ttaccaaaac
    20401 actcccctct tggtgcagtt tgttattgtt ttttatggcc tacctcttat cagtgaccac
    20461 atcatcatga ttccaattta ttggacagcc gttctctgcg tgggactcta tcacggcgct
    20521 tatatcgctg aggttattcg ttcagggatt cagtctattc ctagtggtca gatggaggcc
    20581 gccttgtcgc aaggttttac ctatatcagt gccatgcgct tgattatctt gcctcaggcc
    20641 ttccgcatca ttctccctcc attgaccaac caaattgtta acctcatcaa gaacacatct
    20701 actgtagcta tcatctctgg agtagacttg atgtttgtga ctaagtcttg gtcggctctc
    20761 aacggaaact atatcccagc ctttttaggt gctgctcttc tctactttgc cctatgcttc
    20821 cctgttgccc agtttggtcg caagatggag caagccaata aaaaagccta ttcactttag
    20881 gaggttacta tggaatctat tttagaaatt ttaaccccag ataacctagt ctttatcttt
    20941 aaaggatttg gcttgaccct ctatatttct ctgattgcca tcatcctctc tactatcatc
    21001 ggtaccgtgc ttgccgtcat gcgaaatgga aaaaatccta tcttacgcat tatttccagt
    21061 atttatatcg agtttgtgcg caacgttccc aaccttctct ggatttttac tatctttttg
    21121 gtgttcaaaa tgaaatccac accagcaggt attacagcct ttactctctt tacatcagca
    21181 gccttggctg agattattcg aggcggtctc aatgccgtag acaagggaca atacgaagca
    21241 ggaatgtcac aaggcttcac ctcagcccaa atcctctact acatcattct cccacaagcc
    21301 atccgcaaaa tgctaccagc catcatttct cagtttgtta ccgtgattaa ggataccagt
    21361 ctcctctact ctgttatcgc cctacaagaa ctctttggag ccagccaaat tctcatgggc
    21421 cgttatttcg aaccagagca ggtcttcagt ctttacatcc tgattgccct catctacttc
    21481 agctttaacc tagcgatttc tagcctgtct catatgctag ccaaacgttg gcaacaagct
    21541 gcagaataat actcttcgaa aatctcttca aaccacgtca gcttcacctt gccgtactca
    21601 agtacagcct gcggctagct tcctagtttg ctctttgatt ttcattgagt ataaacagcc
    21661 actctccagt tcaattggag agttttttga tgagagtaga tatttataga cctcaatttg
    21721 acaccataca ttttctatga taaaatgtaa caaattcatt tacaacaaat cgaaatctaa
    21781 atgaaatgga attttctatg aaatcagtca aaggactact ctttatcata gctagtttta
    21841 tcttgactct tttgacttgg atgaacactt ctccccaatt catgattcca ggactagctt
    21901 taacaagcct atctctgact tttatcctag ccactcgtct cccactacta gaaagctggt
    21961 ttcacggttt ggagaaggtc tacaccgtcc acaaattcac agcctttctc tccatcatcc
    22021 tactaatctt tcataacttt agtatgggcg gtttgtgggg ctctcgctta gctgctcagt
    22081 ttggcaatct tgccatctat atctttgcca gcatcatcct tgtcgcctat ttaggcaaat
    22141 acatccaata cgaagcttgg cgatggattc accgcctggt ttacctagcc tatattttag
    22201 gactctttca catctacatg ataatgggca atcgtctcct tacatttaat cttctaagtt
    22261 ttcttgttgg tagctatgcc cttttaggct tactagctgg tttttatatc atttttctat
    22321 atcaaaagat ttccttcccc tatctaggaa aaattaccca tctcaaacgc ttaaatcacg
    22381 atactagaga aattcaaatc catcttagca gacctttcaa ctatcaatca ggacaatttg
    22441 cctttctaaa gattttccaa gaaggctttg aaagtgctcc gcatcccttt tctatctcag
    22501 gaggtcatgg tcaaactctt tactttactg ttaaaaattc aggcgaccat accaataata
    22561 tctatgataa tcttcaagcc ggcagcaaag taaccctaga cagagcttac ggacacatga
    22621 tcatagaaga aggacgagaa aatcaggttt ggattgctgg aggtattggg atcaccccct
    22681 tcatctctta catccgtgaa catcctattt tagataaaca ggttcacttc tactataact
    22741 tccgtggaga tgaaaatgca gtctacctag atttactccg taactatgct cagaaaaatc
    22801 ctaattttga actccatcta atcgacagta cgaaagacgg ctatcttaat tttgaacaaa
    22861 aaaagtgccc gaacatgcaa ccgtctatat gtgtggtcct atttctatga tgaaggcact
    22921 tgccaaacag attaagaaac aaaatccaaa aacagagctt atttacgaag gattcaagtt
    22981 caaataagta atcatactct cctgggattt cccaggagag ttttttatag ccaaatgaaa
    23041 taagacctga acgatggaat tttggcattc aaatcaattg ataagaatat ttta
//
LOCUS       DAVBOU010000033        22095 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBOU010000033 DAVBOU010000000
VERSION     DAVBOU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.033"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..245)
                     /locus_tag="VQ879_001410"
                     /pseudo
     CDS             complement(1..245)
                     /locus_tag="VQ879_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ879_001411"
     CDS             complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ879_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3143553.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2701..3570)
                     /locus_tag="VQ879_001412"
     CDS             complement(2701..3570)
                     /locus_tag="VQ879_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3143554.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3793..4473)
                     /locus_tag="VQ879_001413"
     CDS             complement(3793..4473)
                     /locus_tag="VQ879_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3143555.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4431..5537)
                     /locus_tag="VQ879_001414"
     CDS             complement(4431..5537)
                     /locus_tag="VQ879_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3143556.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5648..5902)
                     /locus_tag="VQ879_001415"
     CDS             complement(5648..5902)
                     /locus_tag="VQ879_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143557.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6260..6793)
                     /locus_tag="VQ879_001416"
     CDS             complement(6260..6793)
                     /locus_tag="VQ879_001416"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3143558.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6780..6995)
                     /locus_tag="VQ879_001417"
     CDS             complement(6780..6995)
                     /locus_tag="VQ879_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143559.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6962..7105)
                     /locus_tag="VQ879_001418"
     CDS             complement(6962..7105)
                     /locus_tag="VQ879_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3143560.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7339..9057
                     /locus_tag="VQ879_001419"
     CDS             7339..9057
                     /locus_tag="VQ879_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3143561.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9168..9515
                     /locus_tag="VQ879_001420"
     CDS             9168..9515
                     /locus_tag="VQ879_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3143562.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9793..10629)
                     /locus_tag="VQ879_001421"
     CDS             complement(9793..10629)
                     /locus_tag="VQ879_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3143563.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10642..11271)
                     /locus_tag="VQ879_001422"
     CDS             complement(10642..11271)
                     /locus_tag="VQ879_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3143564.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11281..11922)
                     /locus_tag="VQ879_001423"
     CDS             complement(11281..11922)
                     /locus_tag="VQ879_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3143565.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12068..13297)
                     /locus_tag="VQ879_001424"
     CDS             complement(12068..13297)
                     /locus_tag="VQ879_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3143566.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13287..14453)
                     /locus_tag="VQ879_001425"
     CDS             complement(13287..14453)
                     /locus_tag="VQ879_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3143567.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14597..15610
                     /locus_tag="VQ879_001426"
     CDS             14597..15610
                     /locus_tag="VQ879_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3143568.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15655..16074)
                     /locus_tag="VQ879_001427"
     CDS             complement(15655..16074)
                     /locus_tag="VQ879_001427"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3143569.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ879_001428"
     CDS             complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ879_001428"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3143570.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17577..18455)
                     /locus_tag="VQ879_001429"
     CDS             complement(17577..18455)
                     /locus_tag="VQ879_001429"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3143571.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18471..19976)
                     /locus_tag="VQ879_001430"
     CDS             complement(18471..19976)
                     /locus_tag="VQ879_001430"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3143572.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19991..20527)
                     /locus_tag="VQ879_001431"
     CDS             complement(19991..20527)
                     /locus_tag="VQ879_001431"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3143573.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ879_001432"
     CDS             complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ879_001432"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3143574.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ879_001433"
     CDS             complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ879_001433"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3143575.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21786..21986)
                     /locus_tag="VQ879_001434"
     CDS             complement(21786..21986)
                     /locus_tag="VQ879_001434"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3143576.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6571 a         4739 c         4032 g         6753 t
ORIGIN      
        1 gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac
       61 tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa aagctctata
      121 atctcttaat aagatttgcc catcagacga aatagaacga tttgaaggcg tttatgatat
      181 ttagctgtac gagagtcttt taaaagtgtt ttgatggttt tgatttcttc tttagttgat
      241 ttcatattac tattgtataa tgctttttga tttgagtcta gtattatact cttcgaaaat
      301 ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc gtcagttcta
      361 tctacaacct aaaaacagtg ttttgaacag tctgcagcta actttctata acaaaatgaa
      421 ataagaacaa gacaaatcaa tcaagacaat caaatcgatt tctaacaatg ttttagaagt
      481 agatgtgtac tattctagtt tcaatatatt atagtttgct ctttgatttt cattgagtat
      541 tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt ctaacttaaa
      601 taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc atacctgaac
      661 caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg gcgattgggt
      721 gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca gtacctgctg
      781 gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga cggtagttgt
      841 tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact tcacctttga
      901 atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt tcgatttcat
      961 cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct tcgtcaagtt
     1021 gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct ttgataccaa
     1081 cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct gaagcaactg
     1141 taccacgtcc agtaattgag aatacgtcct cgactggaag aagcaatggt ttgtcagtgt
     1201 cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata acgatgtctt
     1261 cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact ggaagatcgt
     1321 cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc aattcaagca
     1381 attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt ttaacaccaa
     1441 cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca gttgaagcta
     1501 ctacaaggat agctccgtcc atttgagcag caccagtgat catattttta acgtagtccg
     1561 cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac tcaacgtgcg
     1621 cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata gacgcatagt
     1681 ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg atagctgcag
     1741 ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg tgtggtttac
     1801 tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata tattttatag
     1861 atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt cagctaaatt
     1921 gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact aactaataga
     1981 aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca ctcacttgct
     2041 gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg gcaaatcgat
     2101 caggacaatc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact attctagttt
     2161 caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc ttcttagttt
     2221 gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc ataggactca
     2281 gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata gcaaaatgaa
     2341 atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt ttgagaaaga
     2401 agggaggact attccaactt caacccacta ttaatatata atagaatgaa aactgcacaa
     2461 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     2521 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     2581 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     2641 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     2701 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     2761 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     2821 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcgggtcc
     2881 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     2941 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     3001 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     3061 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     3121 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     3181 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     3241 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     3301 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     3361 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     3421 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     3481 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     3541 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     3601 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     3661 aaaataggat tcatagtttc ctagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     3721 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct tgttcctaga
     3781 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     3841 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     3901 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     3961 ttcagttttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     4021 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     4081 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     4141 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     4201 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     4261 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     4321 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     4381 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     4441 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     4501 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     4561 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     4621 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     4681 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     4741 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     4801 aaacttgcag aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc
     4861 atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg
     4921 gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc
     4981 aaacgccctt gttcatcaac atagcgaact ttcacatttt ctaagattag ttctgccaat
     5041 tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga
     5101 atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg
     5161 atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt
     5221 actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt
     5281 cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag
     5341 cccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca
     5401 atccctttgt ctacccctac aaagtgggag aactttttga actcttcaga accagatcta
     5461 acccaaccat tattaagggc atttgctttt gtatttgtat tctctctcaa aagtttggcg
     5521 attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac
     5581 ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg
     5641 attatcctta acatgatagg taattttcac ctggtataag agtcttcagt agtttatata
     5701 ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag
     5761 tatctttatc aacctgtttc aagacattat tcaagtcatt tgctagccta ttggttgtcc
     5821 tcactgtgaa agttttcttc cagtctgaac cacttttatt aggcttagat atgctcatga
     5881 aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg
     5941 cttcaaattg atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt
     6001 taatgtacta ttttttattt tagtattaag aactccatta atacgatttt taaattctgc
     6061 ttcaaaaaat cccttaattt gttggtgcgc aagttcaaca ttcaaacctt tcttatacaa
     6121 gtcttcattc tgatacaagt cttcattctg aacgatttcg gctacacggt gaatggtttg
     6181 attgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta ctcgataggt
     6241 tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat tcaaaaatag
     6301 ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa gcttgctcaa
     6361 taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta tcttggatgc
     6421 agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca ataacatgag
     6481 gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa tcgcttgtca
     6541 tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct gcaacaattg
     6601 aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct ctaggagccc
     6661 gtgcataagg acgatagagg tagcggtcga ttcctgtttc atcaatatat acgattggta
     6721 aatcttttag gttatccaaa atatcaagaa actcagcgac tttctctggc tcttgttcct
     6781 taaagctcgt catctttttt taaagtgacc ttaatatact ttaaagctgc ccatacggag
     6841 ggcagagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6901 acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc
     6961 tctatgtgtc cttgttcaca tctttctttt cccacgtgaa gagagttctg acgccaacac
     7021 caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatggaatct aatgctcgct
     7081 gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta aaactaagca
     7141 actatatcaa tgttttgtta ttagaagact tacttttttt actgaaatcg aatttttcct
     7201 aacctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag
     7261 cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa
     7321 aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg
     7381 gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat
     7441 gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt
     7501 acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt
     7561 gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac
     7621 ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct
     7681 tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac
     7741 tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag
     7801 gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat
     7861 atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct
     7921 tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag
     7981 gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac
     8041 acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt
     8101 gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca
     8161 tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt
     8221 ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt
     8281 caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa
     8341 tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa
     8401 tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc
     8461 aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac
     8521 aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta
     8581 cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt
     8641 tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac
     8701 gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg
     8761 attatggcta aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc
     8821 gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca
     8881 actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc
     8941 ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa
     9001 gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga
     9061 cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta
     9121 gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt
     9181 tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata
     9241 aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttt
     9301 caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg
     9361 aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg
     9421 taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt
     9481 cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat
     9541 cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa
     9601 aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt
     9661 aacaatgttt tagaaatcac agtgggctat tccatattca attatccaga ttcaatcgct
     9721 attatcgttt tcctagatta caaaaaaact acgttttgct aatcaaaacg cagtttcagc
     9781 cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca
     9841 tttttgactg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat
     9901 cttcttaacc aagtttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag
     9961 tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat aataatttgc
    10021 atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc
    10081 attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg
    10141 atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt
    10201 catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt
    10261 catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt
    10321 ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg
    10381 ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa
    10441 tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc
    10501 aatagtaata gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga
    10561 atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca
    10621 ttttttcatc catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt
    10681 ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg
    10741 caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc
    10801 gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg
    10861 cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa
    10921 gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga
    10981 taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt ggaagacaaa
    11041 tcccagtagg ttgcgcttct gcaattcatc tagctctaaa ggttgtccat tataaaagat
    11101 ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc
    11161 accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac tgaaatcaga
    11221 caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca tagctgcccc
    11281 ctatctataa taactgtact ttttctcaac ttttttggaa ataattgtca caatcccaat
    11341 taaaatcaag taaatggctc ctgccaagaa cataggaacc agactagcat cgcggttagc
    11401 agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc
    11461 cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg
    11521 caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cagcctcata
    11581 ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata
    11641 gttgagaaca aaggcaataa tagctgcagg aaggcgatct aaacgaatcc caatacttgg
    11701 gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat
    11761 gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa
    11821 aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc
    11881 accattcagt aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt
    11941 aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct
    12001 accatataca aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta
    12061 aacattctta caatctctca aacagttctt gcatttgcac atcatctgga accagtttta
    12121 agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga
    12181 tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgtcaactct tgataatgct
    12241 cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca
    12301 aaagattttc tggctcctca ctctgcaagt ctagaatatc ctcataacgc tcctgctcca
    12361 gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag
    12421 taaggagata attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag
    12481 ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg
    12541 cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa
    12601 agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt
    12661 gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg
    12721 ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa
    12781 ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat
    12841 aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc aaacccaata
    12901 tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt gccacatctg
    12961 tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac
    13021 tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag
    13081 caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt
    13141 ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca tacagaagat
    13201 cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct
    13261 cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat
    13321 tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca
    13381 gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt
    13441 aacaaaacaa agagaacatt aataggatgg atgtttaatt gacttcccaa aatcaatgga
    13501 gagacaaaac ggccttcaat agtttgttct acaataaaga caatcactac tttcaaaagc
    13561 atgactggac cagcaatcaa acccaatact agggcaggaa gcatggctag aaagctacca
    13621 agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga
    13681 ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc
    13741 cctcgaacat agttggacaa ctgttgattc acatctgata gaacttgtcc aacaggttcc
    13801 ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag
    13861 agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agctccgcta
    13921 ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc
    13981 tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc
    14041 tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt
    14101 gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata
    14161 aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc
    14221 tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc
    14281 aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa
    14341 ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct
    14401 aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact
    14461 tcctttctat tgtcctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg
    14521 cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt
    14581 acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc
    14641 tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact
    14701 ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac
    14761 tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt
    14821 aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga
    14881 tttggtttac gcagccaact atcacaaggg acaagtcctt gtttataaac gccaggaaga
    14941 tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca
    15001 agcttccccc catgttcact atacagattt aacacctgac cactatctag tgacctgcga
    15061 cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct
    15121 ctatacctat cacagcaagc caggagcagg ctcacgccat atcattttcc ataaccacta
    15181 taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg
    15241 cgttggcgaa tttgtacgta tgcaggttat ttcaacttta ccagaagctt acgaaggctt
    15301 taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg
    15361 tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga
    15421 aatcgttcca acgcatggtc agactccacg tgattttgat ttgacaccca accaaaaatt
    15481 tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa
    15541 tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt
    15601 tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag
    15661 tctatttccg acattaatac ggttaatggc acgttgcaaa gcaatcttag cacgacgttc
    15721 ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc
    15781 acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt
    15841 gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt tcacgtgatc
    15901 tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc
    15961 atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg
    16021 gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag ccataggtca
    16081 cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac
    16141 ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta
    16201 cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacgttga
    16261 agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat
    16321 cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa
    16381 ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca
    16441 aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact
    16501 tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag
    16561 tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg
    16621 atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg
    16681 ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga
    16741 tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg
    16801 tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga
    16861 ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct
    16921 cacgagtacg ttccccaaca ccagtaaata ctgaaatacc accgtgctct tgggcaatgt
    16981 tgtgaatcaa ttcttggatt aagacggttt taccaactcc ggcaccaccg aaaagtccaa
    17041 ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga
    17101 tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct
    17161 ctgcgtcttc tgtaaaagga gcttccaaat caatggtatc tcccaaaacg ttgaagacac
    17221 gtcccaaagt ttctttacct actggtacag agattggacg acccgtgtcc aatacttcca
    17281 ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta
    17341 actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa
    17401 gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac
    17461 cgataacctg agcaatttta cctgaactca tctccttctc ctattctata taagatactg
    17521 tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat
    17581 tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg
    17641 gcacggttat actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt
    17701 tgcatggctg tcatacccgc agcattctca gctgtcttgg catcgataat ggcaccgtaa
    17761 atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc
    17821 aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga
    17881 agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca
    17941 taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga
    18001 acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg ttgaataccg
    18061 cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg
    18121 tctgggtggt attcttcttt caactccata acagctttca aaatagagga attataacct
    18181 ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta
    18241 atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt
    18301 ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga acgacctagc
    18361 ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg
    18421 atttttgttt taatatcatt tagagatact gccatctgac acctctattc ttattggaag
    18481 ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct
    18541 tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa ggtatggaac
    18601 tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtgtcaaa
    18661 gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag
    18721 acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa
    18781 ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca
    18841 gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc
    18901 gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca
    18961 tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg
    19021 ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc
    19081 tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga
    19141 cgacgaagca agagcgatag ttcacgataa gctaccgctt gttttgatag atcatcgtat
    19201 acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac cccagtataa
    19261 ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag
    19321 tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt
    19381 ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc
    19441 gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca
    19501 atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta
    19561 cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct
    19621 ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag actttcacct
    19681 acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta
    19741 aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc cataccataa
    19801 gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc atgagcacgc
    19861 gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg
    19921 aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga
    19981 acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat
    20041 caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt
    20101 cttttacact ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct
    20161 tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt
    20221 tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt
    20281 aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg aaaaaagcaa
    20341 ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg
    20401 ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt
    20461 tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct
    20521 tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg
    20581 actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat ctgcgacctc
    20641 acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc
    20701 ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc
    20761 tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc
    20821 ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc
    20881 tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt
    20941 tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa
    21001 ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat
    21061 tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga
    21121 cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt
    21181 ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa
    21241 tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa
    21301 aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta
    21361 tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg
    21421 gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag ccaaggttat
    21481 tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct ttcatgtagc
    21541 gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat
    21601 tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa
    21661 taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa
    21721 tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca
    21781 tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag
    21841 gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact
    21901 gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata
    21961 cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact
    22021 tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa
    22081 aaattatttc cattt
//
LOCUS       DAVBOU010000034        21608 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBOU010000034 DAVBOU010000000
VERSION     DAVBOU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.034"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ879_001435"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ879_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ879_001436"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ879_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3143577.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ879_001437"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ879_001437"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3143578.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ879_001438"
     CDS             complement(5187..5750)
                     /locus_tag="VQ879_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3143579.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ879_001439"
     CDS             complement(5835..6389)
                     /locus_tag="VQ879_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3143580.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ879_001440"
     CDS             complement(6400..7623)
                     /locus_tag="VQ879_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3143581.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ879_001441"
     CDS             complement(7660..10110)
                     /locus_tag="VQ879_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3143582.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ879_001442"
     CDS             complement(10310..11239)
                     /locus_tag="VQ879_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3143583.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ879_001443"
     CDS             11379..11666
                     /locus_tag="VQ879_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3143584.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ879_001444"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ879_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3143585.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ879_001445"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ879_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3143586.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ879_001446"
     CDS             complement(13807..16353)
                     /locus_tag="VQ879_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3143587.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ879_001447"
     CDS             complement(16476..16916)
                     /locus_tag="VQ879_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3143588.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ879_001448"
     CDS             complement(16891..17760)
                     /locus_tag="VQ879_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3143589.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ879_001449"
     CDS             complement(17738..18238)
                     /locus_tag="VQ879_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3143590.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ879_001450"
     CDS             complement(18249..18947)
                     /locus_tag="VQ879_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3143591.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ879_001451"
     CDS             complement(18940..19176)
                     /locus_tag="VQ879_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3143592.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ879_001452"
     CDS             complement(19276..20202)
                     /locus_tag="VQ879_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3143593.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ879_001453"
     CDS             complement(20277..21092)
                     /locus_tag="VQ879_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143594.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ879_001454"
     CDS             complement(21096..21416)
                     /locus_tag="VQ879_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3143595.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6516 a         4731 c         3812 g         6549 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga atatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt tttccccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac
    21601 agtgtttt
//
LOCUS       DAVBOU010000035        20830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBOU010000035 DAVBOU010000000
VERSION     DAVBOU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.035"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..195
                     /locus_tag="VQ879_001455"
     CDS             <1..195
                     /locus_tag="VQ879_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143596.1"
                     /translation="KKDYIEFKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLI
                     AYRYKEGKLLFVKKEASDVL"
     gene            185..673
                     /locus_tag="VQ879_001456"
     CDS             185..673
                     /locus_tag="VQ879_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143597.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            673..2550
                     /locus_tag="VQ879_001457"
     CDS             673..2550
                     /locus_tag="VQ879_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HET3143598.1"
                     /translation="MYSGKKFLLFSLLGILLGYLFHRLTLLYDSYTGNTLDKWTHLLM
                     EGQDEVLQSPWNVSFTGKSSAFFLLGFVMMLLVYLYLETGKKQYREGVEYGSARFGTL
                     KEKKLFYGKEFSHDTILAQDVRLTLLDKKPPQYDRNKNIAVIGGSGSGKTFRFVKPNL
                     IQMNSSNIVVDPKDHLAEKTGKLFLEHGYQVKVLDLVNMKNSDGFNPFRYIETENDLN
                     RMLTVYFNNTKGSGSRSDPFWDEASMTLVRALASYLVDFYNPPKTREQLIEESRLSQK
                     EYQNLLKRQKKEVEERKKRGRYPSFAEISKLIKHLSKGENQEKSVLEILFENYAKKYG
                     TENFTMRNWADFQNYKDKTLDSVIAVTTAKFALFNIQSVMDLTKRDTLDMKTWGKEKS
                     MVYLVIPDNDSTFRFLSALFFSTVFQTLTRQADIDFKGQLPLHVRVYLDEFANIGEIP
                     DFAEQTSTVRSRNMSLVPILQNIAQLQGLYKEKEAWKTILGNCDSLVYLGGNDEDTFK
                     FMSGLLGKQTIDVRNTSRSFGQTGSGSLSHQKIARDLMTPDEVGNMKRHECLVRIANM
                     PVFKSKKYNSTKHPNWKYLANQESDERWWNYQINPLNQRQENYLDDLRIRDLTFESSL
                     K"
     gene            2571..2813
                     /locus_tag="VQ879_001458"
     CDS             2571..2813
                     /locus_tag="VQ879_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143599.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            2830..3684
                     /locus_tag="VQ879_001459"
     CDS             2830..3684
                     /locus_tag="VQ879_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3143600.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            3738..4097
                     /locus_tag="VQ879_001460"
     CDS             3738..4097
                     /locus_tag="VQ879_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3143601.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            4048..6405
                     /locus_tag="VQ879_001461"
     CDS             4048..6405
                     /locus_tag="VQ879_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3143602.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            6417..9230
                     /locus_tag="VQ879_001462"
     CDS             6417..9230
                     /locus_tag="VQ879_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3143603.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(9261..9449)
                     /locus_tag="VQ879_001463"
     CDS             complement(9261..9449)
                     /locus_tag="VQ879_001463"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143604.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            9468..10034
                     /locus_tag="VQ879_001464"
     CDS             9468..10034
                     /locus_tag="VQ879_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143605.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSERYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            10186..10596
                     /locus_tag="VQ879_001465"
     CDS             10186..10596
                     /locus_tag="VQ879_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3143606.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            10644..16874
                     /locus_tag="VQ879_001466"
     CDS             10644..16874
                     /locus_tag="VQ879_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3143607.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKGL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            16949..17233
                     /locus_tag="VQ879_001467"
     CDS             16949..17233
                     /locus_tag="VQ879_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143608.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            17247..17543
                     /locus_tag="VQ879_001468"
     CDS             17247..17543
                     /locus_tag="VQ879_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143609.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(17557..17754)
                     /locus_tag="VQ879_001469"
     CDS             complement(17557..17754)
                     /locus_tag="VQ879_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143610.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            17914..18555
                     /locus_tag="VQ879_001470"
     CDS             17914..18555
                     /locus_tag="VQ879_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3143611.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            18565..19650
                     /locus_tag="VQ879_001471"
     CDS             18565..19650
                     /locus_tag="VQ879_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3143612.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            19701..19934
                     /locus_tag="VQ879_001472"
     CDS             19701..19934
                     /locus_tag="VQ879_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143613.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            19931..20314
                     /locus_tag="VQ879_001473"
     CDS             19931..20314
                     /locus_tag="VQ879_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3143614.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            20352..20624
                     /locus_tag="VQ879_001474"
     CDS             20352..20624
                     /locus_tag="VQ879_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143615.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            20694..>20830
                     /locus_tag="VQ879_001475"
     CDS             20694..>20830
                     /locus_tag="VQ879_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143616.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARIVGISRNSLSRYENGTSSVSTE
                     L"
BASE COUNT         7147 a         3309 c         4276 g         6098 t
ORIGIN      
        1 aaaaaagact acattgaatt taaacgtgtt ggtatcgttg atgggaaggc agtagaagtc
       61 actcttcgag aaccttattc gagagatcta ctgaaggttg tcaagtcgat taagcaacgt
      121 cagaaattga tagcttatcg ttataaagaa ggaaagctgc tatttgtgaa gaaggaggca
      181 tcagatgtcc tctgaacaac aggaacgaat ggcagttcaa tatgcagagc gtagtctttt
      241 atttactgta aaaagtcttt taaagattct agaatggtct agacgtcagg ctttagcaca
      301 ggattccgcc tataagatag gagtgcagaa attagaagaa ttgctacaat ctccctatgc
      361 gattgatacg attaatctga aaaaagattt tttagacaaa ccaattgata tagagaaatt
      421 taaagctttt ttagaaaaag aagagattcc tttagccatc gcttggcaag gggattctct
      481 acatttctac gcgaaagacc gttcgatttt agacaatcat ttagaccatc ttttagaaaa
      541 aatggttaat gatccggaga aattagctga ttttaccatg gataagtcat tagatgatgc
      601 tattgatgaa gctaaatccc aaattacctt tagacaagaa ggagccgtca aacagaaaga
      661 gatggtgaga tgatgtacag tggaaaaaaa ttcctactat tctcactgtt aggtatctta
      721 ctaggctatc tttttcatcg tttgacgctt ttgtatgatt cctatactgg aaatacctta
      781 gataaatgga ctcatcttct gatggaaggt caagatgaag ttcttcagtc gccatggaat
      841 gtttctttta ctggaaaatc aagtgctttt tttctactag gttttgtgat gatgttactg
      901 gtttatctct atctagagac tggtaaaaaa caataccgag aaggggtaga atacgggagc
      961 gcccgttttg gaactctaaa agaaaagaag ctcttttacg gtaaggaatt ttctcatgat
     1021 acgatcttag cacaagatgt tcgtttgaca ttattagata aaaaaccacc ccaatatgat
     1081 agaaataaga atattgcggt gattggaggt tcaggaagtg ggaagacatt tcgctttgtg
     1141 aaacccaatc tgattcagat gaatagttct aatattgtag tggatcctaa agatcacttg
     1201 gccgagaaaa caggcaaact ctttttagaa catggctacc aagtaaaggt gttagattta
     1261 gtcaatatga agaactcaga tggctttaat ccttttcgct atatagaaac agaaaacgat
     1321 ttgaatcgca tgctgactgt ttattttaat aacaccaaag gctctggctc ccgaagtgat
     1381 ccattttggg atgaagcttc tatgactttg gttcgagctt tagcctctta cttagtcgat
     1441 ttctataatc cacctaaaac aagagaacag ctcatagaag aaagtcgttt aagtcaaaag
     1501 gaatatcaaa acttgttgaa acgtcaaaaa aaagaagtgg aagagcgaaa aaaacgaggt
     1561 cgttatccaa gttttgctga aatctcaaaa ctcattaaac acttatctaa gggtgaaaac
     1621 caggaaaaaa gtgtcttaga aattctattt gaaaattatg ctaaaaagta tgggactgaa
     1681 aattttacca tgcgaaattg ggcagatttt caaaattata aggataagac tctggattct
     1741 gttatagctg taaccactgc taaatttgcc ctcttcaata ttcaaagtgt catggacttg
     1801 accaaaagag atacccttga tatgaagaca tggggcaagg aaaaatcaat ggtttactta
     1861 gttatcccag ataacgatag tacctttcgc tttctttcag ccctcttttt ttcaaccgta
     1921 tttcaaaccc taacaagaca agcagatatt gattttaagg gtcaattgcc tcttcatgtg
     1981 agagtttact tagatgagtt cgcaaatatc ggagaaattc cagattttgc tgaacaaacc
     2041 tcaacagtcc gttctcgaaa tatgagtctc gttcctattc ttcaaaatat tgcccaactt
     2101 caagggctct ataaagaaaa agaagcttgg aaaaccattt tggggaactg tgatagctta
     2161 gtctacttag gtggtaatga tgaagatacc tttaaattta tgagtggctt actcggtaaa
     2221 caaaccattg atgttcgaaa tactagtcgt tcctttggcc aaacaggttc aggatccctt
     2281 tctcatcaaa agattgctcg tgacttaatg acacccgatg aggtcggaaa tatgaaacgg
     2341 catgaatgct tggttcgaat tgccaatatg cctgtcttta aaagcaaaaa atacaattcc
     2401 actaagcatc caaactggaa gtacctagct aatcaagaaa gcgatgaacg gtggtggaac
     2461 tatcaaatca atcctttgaa tcaaagacaa gaaaattatc ttgacgacct tagaattcgt
     2521 gatttaactt ttgaatctag tttaaaataa aaatagaaaa gaggaaatag atgattacgc
     2581 attttaaagg ttttgtttat ggagtagacg caagtgctat gtttgcacaa gctatgtctt
     2641 tgttacagaa gggattgatt gcagttggtg cctttctcgt tgttgtgggg attgtcaacc
     2701 ttgcaaccaa cattaaagat ggtggaccag gtgttcggaa tgccattctt gaaattgtcg
     2761 gtggtgttat ggtaggggct gctggagcct ttgtaaccca gatttcaatt taggaggata
     2821 aacaatgaca tgaatcttag tttagtctca ccctttgttt accttgcatc tgaaaaaata
     2881 tcagctgaaa atttatttga aggatttaat gtggatttac aatctacggt agatctgatt
     2941 aaatccctat ctagctacaa tccaacagtt tggacttata tgtctagtat tactaaaagt
     3001 gtcatgcagc ctcttggagt tgcgatttta tcagttgttc tcatcttaga attttcgaag
     3061 atggcaaaga agattgctaa ctctggtgga gcgatgacct ttgaagcatt agcgccgatg
     3121 ttgattagtt atattatggt cgcagtggtc attaccaata ctaccgttat agtagaagct
     3181 atcatcggga ttgcgagtca cgccatcgaa caagtggcct cgattgtggc tcacggtggg
     3241 gcgaagtatg atacactctc tggattaaaa ggttcaggat ttattggccg gatgattgtg
     3301 ggctttttcg ctctccttat ctggcttgtt cggatagtaa gtgcagccat ggttaatctt
     3361 ttggtatcta ttcgatttat tcaactctac cttatgatcc catttgcccc tcttacgatt
     3421 ccaacatttt taagtgatga atggaagtct attggtattg gctatttaaa aaatattatg
     3481 gtctatgcgg tacaaggggt tctcattttt ctgattgttt ctcttgttcc tttgtttgaa
     3541 tctgctggga aaatagctgt ttcaaatggt gcaggagtct tgcaatcact tgcgattatg
     3601 tttggtagtt tagtacaagc tatcttactg attattgccc tcgttggttc tcaacgtacg
     3661 gctcgctcaa tcttaggtat gtaattagat aaaggctagg aagtgattgc ttcttagcct
     3721 ttttagaaag gaaagtcatg aatacacgtg tctttaaaga catctcaaaa taccaacaca
     3781 gggcttggtt aggtttcacc acaagacaaa tcatctttgt tttaccagcc tttattgtca
     3841 caattattgt tttgggcttg aatctctttt tctggcaatt tggagattgg tttgtttacg
     3901 gttttgtgtt tgcttttacc atccccctaa tgctttttgg agtctataaa cccaatgatt
     3961 tatattttga acattatttg aaataccgtc ttcattttga attaacggtt cccctacgca
     4021 caattacagg aaagaaagga cctgaacatg aaaagaaaat caaatacatt aaagaaacaa
     4081 aaaacttcaa tgactaataa aaaggaagaa gttaaaggga aaaaagagga agtgttaccc
     4141 tcaacggcta atactctttc ctatcaagcc ctgtatcaaa atggtctgat gcaggtaaaa
     4201 gaagattatt tctcacaaag ctatttactt ggtgatgtca attaccagac cgttggttta
     4261 gaagataagg gcgcaatcat tgagaagtat tctgatttga ttaactcact agatgaccaa
     4321 accaacttcc aattgactat ctttaataaa agattgaatt tagaaaagtt tagacaaagt
     4381 gttttgtatg aggaaaaaga agatggatat gatacctatc gtaaagaatt gaatcggatg
     4441 atgaatcaga atttagatag tggtgaaaat aacttttcgg ctgtaaaact gattagcttt
     4501 ggaagaaagg attctaatcc caaacaagcc tatcgttcct tgtctcaaat aggagaatat
     4561 ttcaagagtg gtttctcaga aattgatgct cgatttgaat ccttggctgg agaagatcgt
     4621 gtgaacttgt tggccgacat gcttagagga gaacaccatc ttcctttttc ttaccgtgat
     4681 ttaacgagat ctggtcagac aactcgtcac ttcatagccc ctaatctctt ggattttaaa
     4741 aacaagaatt acctacaaat caatgaccgc ttattacaga ttgtctatgt cagagactac
     4801 ggcatggaat taggggatca gtttattcga gaccttatgc aaggagattt ggaattgatt
     4861 gtaagccttc atgctcaaag ttcgaccaag gcagatgcca tgaagaaact acgaacaaag
     4921 aagaccttga tggaatccca aaagattggg gaacaacaaa aactagctcg tacaggtatc
     4981 tatttggaaa aagtaggtca tgtattagaa agtaatatcg atgaagctga agaactttta
     5041 aaaaccatga ccgagacagg tgataaactg tttcaaacgg tcttcttgat tgggatcttt
     5101 ggtcaggatg aagaagaact caaacaagct ctagatacga ttcaacaagt ggccggctca
     5161 aatgacctaa tgattgataa acttccatat atgcaagaag cagcctttaa tagtttgctg
     5221 ccatttggtt gtgatttttt agagggagta tcacggagtt tattaacatc taatgtagca
     5281 gtgaactcac cttggacttc agtagactta caagaccgca gtgggaaata ttacggtatc
     5341 aatcaaatct caagcaatat tattactatt gatcgaagct tattaaatac accgtctggt
     5401 ctgattttag ggacatctgg agctgggaaa gggatggcaa ctaagcatga gattatcacg
     5461 accaaaatca aggaatctgg tgaaaatact gaaattatca tcgtggatcc agaagcagaa
     5521 tacagtgtca ttggacgagc ttttggggga gaaatgattg atattgcgcc agattcccaa
     5581 acctatctca atgtacttga cttgtctgat gaaaatatgg atgaggatcc tgttaaggta
     5641 aaatcagaat ttcttttatc ctttatcggc aagttattgg ataggaaaat ggatggaaga
     5701 gaaaaatcga ttatcgaccg agtcaccaga ctcacctatc agtcatttaa agagccttct
     5761 ttggaagaat gggtctttgt cttgagtcaa caaccagaag aagaagcgca gaatttggca
     5821 cttgatatgg aactgtatgt cgaaggttct cttgatattt tttctcataa gaccaatatt
     5881 cagacaggat ctaacttctt aatctataac gttaaaaagt taggagatga gctgaaacaa
     5941 atcgctctta tggtagtgtt tgatcagata tggaatcgtg ttgttcggaa ccaaaaatta
     6001 gggaagaaga cctggattta ttttgatgaa atgcagcttc tcttattaga taaatatgcc
     6061 agtgatttct tctttaaatt gtggagtcgt gtcagaaaat atggagctag tccgactggg
     6121 ataactcaaa acgtcgaaac cttattgtta gatccaaatg gtagacggat tattgcaaat
     6181 agtgaattta tgattctcct caagcaagca aaaaatgacc gagaagaact ggttcaactc
     6241 ttaggcttgt caaaagaact cgaaaaatac cttgtcaatc cagaaaaagg ggcaggactg
     6301 ataaaagctg gttcagttgt cgtacccttt aaaaataaga ttcctcaagg tactcaattg
     6361 tttgatatca tgagtacgga tcctgataaa atggcttcta attaagggga agtagaatga
     6421 aggataaaag aaaaatcata cgtgcccgaa aggcatttag aagaagccta aaagatgaga
     6481 aaaaattctt gaaaaaagga aagaaggagg taaggaaaca gaaaaaagat tccgctgtac
     6541 tggatgaaaa agcatggaaa aaagagataa aagaaaagct agaggagatg agagaggctt
     6601 caaaggagag agtaaaacaa gcaaatgaag actacaatca tattcttcaa aatagtcctc
     6661 catctctttt gaatcgcaaa gaattaagag acagacggtt gcctcatgct aggaaacgat
     6721 tgaaaatagc caagaagcaa tttagagaag ccaaggtaga agcaaaagaa gaaagaaaag
     6781 agggtcgtaa agaaagaaaa accaatcaaa aatttctcta cggtcaggaa tcgaaagcaa
     6841 aatcaaattt tttctttcaa gggaagagtt tagaagaatt aaaagctaag aaagaagtca
     6901 aggacgccaa agaaaattta aaatctacta aacaagccta taaatccaaa aaggttagta
     6961 ggaaagccaa aactttcctt tatgtccttg gacgtgaagg tggagagtta gcttcagaaa
     7021 atgaagattt agaaggctat cgcacacttc aagagaccat tagaaaaggg aaacgctaca
     7081 gtcggctttc ttataatctt ggaaaagcta gtgtcaaaac aggacaagca acaggtcgtt
     7141 ttaccaagaa aagactgacc aacacaaaag agcgatacca tcattttaag gatggaaaag
     7201 gatggaaact agcgaaagat aatccaagtt cctttaaaaa tcggtatcga aaattaaaga
     7261 aacaaggcct tacaagtgta cgaaatatct atcaaaaact aaaagcagcc ttttccttct
     7321 ttacatttgc ggctgggaat cctgcaacct ggatagttgg aggaatagtc tttcttcttt
     7381 tacttatgat gagcttcttt ttaggatttt catctgctag tttaattcaa caagatgaat
     7441 ttgaattaac aaaagcttat acccacctaa cttgggaaga cgcagaacat acccgaacca
     7501 atgacaaagg aattacctat tacacaaaag ttgatgatgt gatggggtat atgaacttta
     7561 aattccatga ctatgagtta cacaaaccag ttcacttatt tagttcagaa acttacaagg
     7621 attatctatc tactttgtgg catgatttaa acgatgggga agatttgaaa tccatgcaag
     7681 acctttatga aactcctaag tataaactat cgaaagacga tcaagaggaa atgaaggaac
     7741 taaaagaaga aggtgtgtat gcttccatgc aggaattgga caatccattt gaagggaaaa
     7801 gtaacgaaga tagtttaacc atgacttatc gttatggata ctatgattta gacggaaaac
     7861 ctactcttca ggagtacatt ctactagaag ctaaagctca ccaagcaatt gtcgcaccaa
     7921 tggatggagt tgtatctcta gatggcgaca atgttattct cactaacgga aaaggagaaa
     7981 acgagagtcg cttaacctta tattccattc ataatggccg tgcgattgag gggacaagag
     8041 tcctaacggg tgatgttatt ggtgagacac cagatgatac aggtttgaaa gtttcctatc
     8101 aaaagtataa gaacaagaaa gaaaaattgg tgtatgttaa tccgcaattt tattttccaa
     8161 aagtcattca acttcagaca actatcttac ctgccattgg tcagtttggt ggggatgagt
     8221 ttgaacgagc gaaacatatt tatgagtttt tgaaatctca aggggcaagt ccccaagcca
     8281 ttgcagctat tttaggaaat tggtcggtag agtcttctat caatcctaaa cgagctgagg
     8341 gagattattt atctcctcca gttggcgcta ccgcttcctc atgggatgat gaaacctggt
     8401 tagcgattgg aggtccagcc atttatagtg gtgcttatcc taatatcctt catagaggtt
     8461 tggggttagg tcaatggacg gatactgcag atggttcaac acgtcataca gctttattga
     8521 attatgcaca tagcaaaaat aagaagtggt atgatttaga cctccaactt gattttatgc
     8581 ttcatgggga tagtccttac tatcaaagtt ggttaaaaga tttctttaaa aatacgggca
     8641 gtgcagccaa tctcgcccaa ctcttcctca cctattggga gggaaattct ggtgacaaac
     8701 tactggaaag acaaaccaga gcaacggaat ggtattacca aattgaaaaa ggcttcagcc
     8761 aaacaaatgg aggacaggca aaaagtgacc cacaatccct tgaaggggtt cgtggggact
     8821 tgtatgatca ttctgttcct ggtggtggag atggtatggc ctatgcctat ggacaatgta
     8881 catggggcgt tgcggctcgt atgaaccaat taggcttaaa attaaaagga agtaatggag
     8941 agaagatttc aattattaat accatgggaa atggtcagga ctgggttgcg acagcttcaa
     9001 gtcttggtgg ggaaactggc tctacaccaa gagcaggtgc cattgtttct tttgtgggag
     9061 gtacacatgg tacaccagcc atctacggtc atgtggcttt tgtcgagaaa gtatatgatg
     9121 acggttcttt ccttgtgtct gaaaccaact atggtggcaa ccctaactat acctttagaa
     9181 aaatctctca agcagatagt gcaataagtt ttgcctatac tacgaaatag aagagtttac
     9241 acttgaaatt ttaaccattt tcaggtagaa taaatagtgt agatgagtag tcggctcatg
     9301 gtcaatctga tagtaatctt ggacataagg gccaagcggt ggcggacacc agaacgaaat
     9361 ccgatagcaa tcttggacgt aagggccaag cggtggcaga caccagaata aaccgactga
     9421 ctaggtggct tacagactct gtaaaccacc ttttttgtga ggaaaatatg gcaaattcta
     9481 gagattatcg taatccaaat tacaccgaaa aaataaaact tcagcgtttt tttactcagt
     9541 tacaaattgc ggcttctttt tttaaagaac acttcgttgg caaaatcatg tattatgaaa
     9601 cagaaataga aagtgttgaa cttcattttt cacctactaa tttcatgcac ctatgtggtg
     9661 ttgattacca aaaaggtgca ggtagtttct ttgacgattg tttaaataga catgtcataa
     9721 ttgatgagtt gaaaataaaa aaagatggaa ccacgatgca aaagttacaa gttttaggat
     9781 ccattgagga gttattggga aagcatgttc atctaactgg ttcagaacgt tatttgtatt
     9841 tggagtttga ttatgctcta cgtacaagaa aacagatact agcattaaca ttgaaagaga
     9901 catcaaggaa aattgttcct caatctttat tagatttgaa gagaaagaca gtatttccaa
     9961 aaggtcaaaa agtaatttca atttactcaa aacatttaca aacgtcggaa cttttttatt
    10021 atttaaaaga ttagtttaca tatcttttgt ggcataaaat atatttttat cattttcagg
    10081 agaacgcagt tttggctcgt tctctttttt tgttgtgata cttctttcaa ggaatatttg
    10141 gtaggattgg agtgaaaaaa gattaactag gaaagaagga agtatatgga aggcatttat
    10201 caacgtgatt cggatcaaga tggattaact gatgctcaag aattggcgct aggaaccaat
    10261 cctcttagcg cagattctga tggtgatgga cgttcagatt tagtggaagt agaagaagga
    10321 accaatccct tagaaaagga tttacaagac atagaccaaa caagtataac tgaaccgtct
    10381 tcagtattta tggaaatgaa acaaaagatt tcagatatga tggagagtca ctacaaggaa
    10441 tttatacagg ctcttattag tattgaaaca gggattgaaa acgaacaaga cctagaagac
    10501 ttatatactt actacatgag aacagattct atttctcttt tgtctagtga tttagaaacc
    10561 agtcctcaaa aggttgaaat ggagatagag ttgtagggga atcatgtgat tctcctattt
    10621 tcgtatagat gaaaggagcg agtatggaag taatgaaatt attggctatg tttcgtggaa
    10681 caattccaaa agatagggag aaaatggacc tatttcttcg ctatcaggcg caacattttg
    10741 atgagaaatg gcaggacttg gtagagagtt ttttggttga agagggcaag atagaagaga
    10801 tacctcatgt gtattcgttt catcaagata ttatttcttt cctagaggct agttctgaaa
    10861 ataatgacca agatttagaa agttacacaa gaaattttgg acaagcaggt ctaagtaaat
    10921 tatctcaatt aagtaatttt gagaaaaact tggtgctaga agtcgcaacc tataaccttt
    10981 ccactcgatt ttatatccaa tctgaaaaag agaaactaac accattaagt gagcttgtat
    11041 gtcatcagaa acaggatgtc aatttagtca atgtctatcg ggttgcgaat aatctatctg
    11101 accgcattag tagagatata gaggagtttc ttctaatggt tgactcaaaa gagcttaaaa
    11161 aagaagttct tgagattcat tttgaagaaa aagagggaga tgttctagct tatttgggtt
    11221 cagaattgat ggctacttta gatactgtta cggatcttgt ccatcatgaa gaaaactacc
    11281 aacaacttcc actgacacaa aagctgaaga ttattactca ttttgatgaa gtaaaggcta
    11341 taagagaaaa gtctaagcaa gtagcggaat ccttatctcc ttcaagtgat attgaacagg
    11401 aaacggaaga aacgaactcc ttttctaata tcgataaaat tgtagaagaa gctttgaggg
    11461 aatatccaat cggttcacaa gtaagttata aaggacaagt atttcagttg gtttcgattg
    11521 aaaatgcaca gttaaatgac ttagttcgcc tagagctatt caaagattcc aaccagttat
    11581 ttgaagagaa tcctatctta tacttgaaca gtttggaaga gattgaacaa gtattgtctc
    11641 atgtagaact tgaaaaagaa gattcagaga ttgagattga ttcatcaagt gaaagtcagg
    11701 aaatagattt gttttcctac ctggaagaag aaaatgaaaa tgaaaaggaa aaggaaaagg
    11761 ataaagaaac agaaacgctt attgtaggca tagaagagac ggatgtccct gttcaagatt
    11821 ttgtttttcc agatgattta gaggactttt atcctaagac aaatcgagaa aaaattgaaa
    11881 cgaatatcgc cgcaattgaa cttgttaaaa gattagaaaa agagggacga caagcgaatc
    11941 cagaagaaca agagctacta gccaagtatg tcggctgggg tggtcttgcc aatgaatttt
    12001 tcgatgaact caatccaaag tatgaaacag aacgtttaac tcttaagagt ttagtaagta
    12061 aatcagagta ctccactatg aaacaaagtt ctctcacagc ctattataca gacccaatga
    12121 ttattcgcca gatttggcaa aaattactgg atgatggttt tgagggagga aggatattag
    12181 atccttctat ggggactggg aacttctttg cggcgatgcc tagaagtata cgagataaat
    12241 cagaactcta tggagttgaa ttagacagtg tgacaggcgc aatcgcaaaa caactccacc
    12301 ccaataccca tattgaagtg cgaggatttg aagaagttcc ctatcaaaat aatagttttg
    12361 atttagtctt aacgaatgtt ccttttggaa attttcgcat tgccgataaa aactatgata
    12421 aaccttacat gattcatgat tactttgtca aacactcact tgatttagta agagacggag
    12481 gacaagtgtc gattatctca tctataggga caatggataa gcggacagat aatgtcttac
    12541 aagagattaa atctaacact cattttttag ggggagttcg tttgccggat acggctttta
    12601 aaaagattgc aggtactcga gtgaccacag atcttctctt ctttcaaaag gatcaagcaa
    12661 agaatcttaa tgaggaggaa cttgtcttta gtggctctat tccctttgaa gaggataagc
    12721 gtgtctggat caatccttat tttgatggga aatacaatac acaagttttg ggtcaatatg
    12781 aggtgcgtaa ttttaatgga ggaactctca atgttaaggg ggtatcagaa acattagtta
    12841 ctgaaataat gaaagcattc gagaatgtgg aagcacctaa acaaattgac aattctttga
    12901 aagcacctgt ttttatccaa gaagaagtag ataattctat cccaagtcgt atatgtgagg
    12961 acttagcgct ctattctttt ggatatgagg gaaatcaaat ttattaccga gatacgcatg
    13021 gcattcggaa aagttcaaaa gtagacgaaa ttagttatta tgtagacgag aagggagaat
    13081 ttaaagcctg ggacagttct ttgtctgaac ataaaataga tcgattcgtg caacttcatt
    13141 tgacagatga ggaagcacta gatgtataca agtcagaaga agcgagtaaa agagggaaat
    13201 ataagggact gttcaaaaaa actgtctttt atgaaagtcc cttatcggat aaggatatta
    13261 gtcgcattaa gggtatggtt gatttgagag agacctatca agccttaatt gaaattcaac
    13321 gtcatccaga ttatagtcgg tctgattttc agatattact tagtaaactc aatcgtgatt
    13381 atgaccgttt tgtaagtcaa tttggatact tgaatgcctc agttaatcgg aacttatttg
    13441 atagtgacga taagtattct ttactagcaa gtttagaaga tgaatacatt gattctaaag
    13501 atcagaaagt aaaatataaa aaatctttag cctttgagaa agcattggtt aggccggaga
    13561 gagtgattac aagagtatca acggctttag atgccttaaa ctctagttta tcggatggta
    13621 gaggggttga tttagactat atggtatcaa tttaccctga acatagtcaa gctgctattt
    13681 tagatgagtt aggtgaccag attttaatgg atccagaaag ctatttaaga ggtgaaagaa
    13741 aatatctttc taagaaccag tttttatcag gagatattct caacaagata gaagtagttc
    13801 aactattagt agaggaaaac aaccaagaat atgattggaa ccatgcttta gatttgttag
    13861 aatctgttcg ccctccaagg attcatctgg cagatattga gtttaaaata gggtcacgtt
    13921 ggattcctca atccgtttac ggtaaatttg cctttgaatg ttttaccaat cgtgaatttg
    13981 aattgtcttc acctgatgtt gaacaagtta ttgaagtgaa tcctgtcgat gggcaggttc
    14041 atttaaggac atcatttgct tatcgctatc caagtgccaa agatagtagt cttggagtta
    14101 gtgggtcacg ttatgataca ggaagaaaga tttttgagaa tttacttaat tcgaaccaac
    14161 cgacgattac tatgactgtt acggaaggag aaaagaaaaa gaccatcaca gatttggaaa
    14221 aaacctctgt tctaagagca aaagagcagc atttacaaga gctctttcaa gaatttgtct
    14281 cacggtatcc agaagtccaa caagttattg aggaaagcta taatcgtctt tataatcgaa
    14341 cggtaagtcg agagtatgac ggtagccatc tagtcattga tggattggca caaaacatca
    14401 gtcttcgtcc tcatcaagag aatgccattc aaagaatcgt agaagaaaaa agagccttgt
    14461 tagctcatga ggtaggttca ggaaagacct tgaccatgct tggtgctggg tttaaattaa
    14521 aggagttggg gatggttcat aagcccttgt atgtagtacc ttctagtttg tctgctcaat
    14581 ttggccaaga aatcatgaaa tttttcccta ctaaaaaagt ctttgtgact actaagaaag
    14641 atttcgttaa ggcaagaaga aaacaatttg tgtcacgtat tattacagga gattacgatg
    14701 ccattgtcat tggggattct caatttgaaa aaatccctgt cagtaaggaa agacagatga
    14761 attatatcga ggataaactc aatgaattac gagagattaa aacacattct gaaaataagt
    14821 atactgttaa agaagcagag caatcaataa gtggtctaga gaaacaattg gaagaactcc
    14881 aacgctttaa tcgtgatagt tttattgatt ttgagaactt aggaattgat tttctctttg
    14941 tggatgaagc acatcacttt aaaaatattc gtccaattac gggacttggg aatgtagcag
    15001 ggattaccaa tacaacctct aagaagaacg tggatatgga aatgaaggtt cgacagattc
    15061 aggaagagca tgattttaaa aacattgtct ttgcgacagg aacacctgtt tccaattcta
    15121 ttagtgagtt atatactatg atgaactata ttcaaccaga tatcttaaaa cgctatcaag
    15181 ttgattattt tgactcttgg gtaggtgctt ttggagaaat tcaaaactct atggaattag
    15241 ctcctacagg ggataagtat cagcctaaga aacgatttaa aaagtttgtc aatctacctg
    15301 agttgatgaa aatctataaa gaaacagccg acattcaaac acaagatatg ttggatttac
    15361 ctgtaccaga agcccatatt atccctattg agagtgagtt aactgaaaac cagaaactct
    15421 atttagaaga attggttatg aggtcagatg cggtcaaatg tggaacagtt gatccgagcc
    15481 aggataacat gttaaagatt acgggtgagg cacggaaact agctattgat atgcgtttat
    15541 tggactctag ctatagtcta gcagacaatc ataaactgct tcaggtagtt gataatgttg
    15601 aaagaattta tcgtgaggga atgggaaata aggctactca gatgattttt tcagatattg
    15661 gaacacctaa gaaaaaagat aatggctttg atgtttattc tgaaataaag gctttattgg
    15721 ttgatagagg aatccctagt aaggaaattg cctttgtaca tgatgccaat agtgatgaaa
    15781 agaagaatag tttgtctcga aaggtcaatg caggagaagt gcggattctt cttgcatcaa
    15841 ctgaaaaagg aggaacaggt ttaaatgttc agagcaagat gaaagcagtt catcacctgg
    15901 atgttccgtg gagaccaagt gacattcagc aacgcaatgg acggattatc cgacagggaa
    15961 atgaaaacaa ggaagtggat atttaccact atattaccaa aggttcgttt gataattatc
    16021 tatgggcaac tcaggagaac aaactccgtt atattaagca gattatgact tctaaggagc
    16081 cgattcgtgc tgcagaagac attgatgagc agaccatgac agcttctgat tttaaggcac
    16141 tagcaacagg taatccttat ctcaaatata agatggaact agagaatgat ctaactctat
    16201 tagaaaatca aagacgcgcc tttcaacgca gcaaggatca ctatcgtcat acaatctctt
    16261 actgtgaaga aaatatgccc attcttgaga aacgattaag caagtatgaa ggcgatattc
    16321 aacagtctga aatatcgaaa gaccaggcat tttctatgac ggtaggtaag caagcttttg
    16381 atcaacgagc tgaagcaggt gaatctctac accgtcttat ccgtcataat caagctgaca
    16441 gcaaagaatt tcgtacccta gcaagctatc gaggatttga cattaaaatg cttagtcttc
    16501 caataaatca acctcttcct gaaaccttct ctgttaagat tgtaggagaa aatcagtatt
    16561 ctgtcagttt agatttgtat tctcctttgg ggacaattca aaggcttcag catacaattg
    16621 atcacattaa agaggaccaa gtgaaaactc agaacttatt ggatgaatta aaggataaat
    16681 ggactactgc taaagttgaa attgagaaaa attttccaaa ggaagaggat tatcaaacta
    16741 aaaaggccga atacgatgta ctcgcgccat tgattgaaac agaaacggat ttagatatta
    16801 tagatcaggc cttaagacaa ttccacgaaa aaggaaaaga aaagcaagaa caactttctt
    16861 ttgaattaga ttaaaaaata tatataaata gcggacaaga aaagaaaagc gcggtagaat
    16921 aaagatagaa agaaacgagg taacgattat gatggaagat acctattatc aattagaaga
    16981 ggccttggta cagggatttc aaacgcctga agaataccaa gcctacaagg agctaaagga
    17041 acattatgag gaagtgacag gcgattacag tttttctaaa cgagaactca ctagtcaatt
    17101 ggaaatctct cttcagaatc atcgaggtgt ggactttgaa gaacatgaaa aagaggagta
    17161 tttggactta gttcaaaaat tagaagagtt tgattcctct cttgccaccc attatcgtca
    17221 attgattgac tagaaaggag aaagtcatga atgatttact ccttatccca gtaatttttt
    17281 tagcagtagg agggattctc attcttttat ggagactctt tcttattgcc agtagacttt
    17341 tcctgattgg ttttgtcagt tttcttattt tcgtagaagt ctatggaatt tatctgttct
    17401 ttactgaacc tactttatat tttgatgata tcagacaaca tggtttaact agttttacgg
    17461 ctgtgtacct tttcatcaat ctgatgttgg ttctaggatt cagttggcgc ttcattaact
    17521 ccatgaataa ggaaaaaatg tgaacttttt agatagttaa aagactttat ctgaatctaa
    17581 attcggataa ggttttttat ttgccttgat tctttcatat acttcatagc taaattggag
    17641 taataattta tgaaaatcat tatcctcact attattagtt gtatttatgg cttgtttatg
    17701 tcgttcaata tgagaaagag ctcttctcaa attttcttct tttaatttgt tcatatttat
    17761 attataaact gaagacagct ggttttgaca tttttctctg aactgtacga ttttgcgcca
    17821 gaaatgtagg aattaccttt cgttgtgatg tgataaaact tacaagttct ttttgttatt
    17881 cttgacctag tttttataga aagaaggtct aagatgttaa ataaagtcaa aactaaagcc
    17941 ttaattagtg ttggagcagt ggctgcaact agctttattc tcatgatggg atatactgct
    18001 ggtcaacact caactgctaa acaaagtcgc aaagaaatcg aattggctgc agctaaactt
    18061 gtagaggata aacaagcaga agataaagcc agcattttgt catcggatac tgtaaaagaa
    18121 tttttgactc agtactatac gaaagaaaag ctcggagaaa ataatacacg tattcaacct
    18181 tatatgactg aatcggcata ttctcaagaa ttgaccagtc aaaacgatgc catgaaccaa
    18241 gtgtataagg actatatttt ggattatcat tttgaaaaag ctgatatctt tgttaatcag
    18301 actacgaatc aagctattgc catggtctct tataatgtaa cctatgtatc tgatttaaag
    18361 aatgccaacc aatcaaagac taatcagaca gaaacaagaa cagttaagtt atcctattct
    18421 aaactaccag gtaagttatt ggtcaatcaa gtgcaggttt ggaaatctgg gttagatgat
    18481 ttagataagg taactcctaa aactttagaa gaatcatcat caataccatc actgccaaat
    18541 actacgacaa aatgatgata ttgcatggaa atagaagaat gtaagcaaat ttcaattctt
    18601 gatgtagcca atcgtttagg tatctccttt aaacaagttt ctagccgtgt ctatgaacat
    18661 cctgaacacg attcatttcg gattttttca actaccaata cttttaaatg gttttcaaga
    18721 gatattcaag gtgatgttat tgattttgtt cgacttgtta agggaatctc ttttaaagat
    18781 gctctagctt ttctttctga agaacctttt caaaaagaag ctgttcaaga aaaaagagag
    18841 agaccatttt attatccttt aaagagagta gaagattcta actgtagtct ggcaagatat
    18901 tacttaacaa aatgtagagg aatctcagaa gaaatcgtac aaaagatgat tcaacaaggt
    18961 ttgatggcac aagccagttg gaaaacaaat gaaactgttg aacttgttat tgtttttaaa
    19021 agctttgatc atcgtcacaa gctgcaggca gcaagcttac aagggattta taagaatccc
    19081 gctctttcta gagagaggtt aaaaacgatt ctaaaaggaa gccatggaca tattggaata
    19141 tcctttgaca ttggtaaacc aaatagactg gtcttttgtg aatcgttcgt cgacttgatg
    19201 agctattacg aacttcatca acaaagtcta actgatgttc gtttggtatc tatggaggga
    19261 ttaaaaaggt ctgttgtcgc ttatcaaact ttacgactga tagctgaaga aaatcagaag
    19321 ttggaatttt tagatacagt aataccttca aagttattgc ctttgatgaa tacaattcga
    19381 gatacaacta cttattttga taatcatccc gatttattaa cacttgcggt agattgtgat
    19441 gatgcaggaa aagatttttc cgataagtta tttcaagctg gattgcctgt tttactggat
    19501 ttacctgata acgaatctgg gaaagaaaaa atagattgga atgatatcct tagagaaaag
    19561 aaatcagatt tacaattgat acttgagtct gcaaaagaga cattgaggaa tcaaccagta
    19621 agacaaacct ctcaatgttt agaattgtga taacaaaatc aagatgtttt agctaatatt
    19681 agaatgaagg aggatagtat atgaccatta ttgaacgctt agaagaaaag gtcactaggc
    19741 aagaaagtaa ggtagcaaga gagacagaaa aactagctgc ttacaaagag caactggaga
    19801 cagcgatgtt tgcgacgttc aaaaggcgtc aaagcattag tcacatgagt tttgaagaag
    19861 ctcttgacca tgcctttggt aaagaaagac aattcgatga ttctgaattt agaaaggatg
    19921 aaatgagtga atgacaaaag attggaattt taatcaacca ttagaaagta aatcagaaaa
    19981 tcaagaagat ccagataaaa ttgcggcttt atttagaaat catcaaggag gtaatgatgt
    20041 aaattatgaa gcagcttttc aaaagcgtaa acaagcacct gtgacggaat caaattctag
    20101 ttctaaaccc aaagttacag aggttagaac aggaaaagag acagatatca ctacaagtta
    20161 tcagcaacat cttaaaagac tgattgcgga taacaatagc gatattgaaa gtagtcaaaa
    20221 gaaaattgaa gagctacata cgttgattga cacaaagaat aaagacaata agaaattgca
    20281 gtccatttat gatgcgattt cggaattaca ctaagcagtc taaagaggct gctttttttg
    20341 agaggttata gatgtttaca aaaattttta agaaaaatca agacaatagt gatatattta
    20401 agaagttgat tcatagacta tctgatatgt ctgtccaaga tcttgaaaaa attgacagat
    20461 tgttagatat cattttcact ccagaacaag aatcagaaca actaaaaaca gaaacaactt
    20521 atagggaaga aactttggac gacacattaa aaaaagctaa aaatcaactt cataaggaac
    20581 aattggagaa gaatttagag agatttagga aaaatagtca ataacgcacc aaaaatggtg
    20641 catttgcttt ttctaaatgt tataatggtg gtatcaaata aaaggagttt gccatgattg
    20701 gaaagaacat aaaatcctta cgtaaaacac atgacttaac acaacacgac tttgcacgga
    20761 ttgtaggtat ttcacgaaat agtctgagtc gttatgaaaa tggaacgagt tcagtctcta
    20821 ccgaattaat
//
LOCUS       DAVBOU010000036        20670 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBOU010000036 DAVBOU010000000
VERSION     DAVBOU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20670
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.036"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(2..1681)
                     /locus_tag="VQ879_001476"
     CDS             complement(2..1681)
                     /locus_tag="VQ879_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3143617.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1683..1916)
                     /locus_tag="VQ879_001477"
     CDS             complement(1683..1916)
                     /locus_tag="VQ879_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3143618.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ879_001478"
     CDS             complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ879_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3143619.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ879_001479"
     CDS             complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ879_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3143620.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ879_001480"
     CDS             3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ879_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3143621.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3919..4356
                     /gene="rimI"
                     /locus_tag="VQ879_001481"
     CDS             3919..4356
                     /gene="rimI"
                     /locus_tag="VQ879_001481"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3143622.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ879_001482"
     CDS             4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ879_001482"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3143623.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5396..6702)
                     /locus_tag="VQ879_001483"
                     /pseudo
     CDS             complement(5396..6702)
                     /locus_tag="VQ879_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7036..7330)
                     /locus_tag="VQ879_001484"
                     /pseudo
     CDS             complement(7036..7330)
                     /locus_tag="VQ879_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7437..7730)
                     /locus_tag="VQ879_001485"
                     /pseudo
     CDS             complement(7437..7730)
                     /locus_tag="VQ879_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7973..9177
                     /locus_tag="VQ879_001486"
                     /pseudo
     CDS             7973..9177
                     /locus_tag="VQ879_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9170..10046
                     /locus_tag="VQ879_001487"
                     /pseudo
     CDS             9170..10046
                     /locus_tag="VQ879_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10133..11749
                     /locus_tag="VQ879_001488"
     CDS             10133..11749
                     /locus_tag="VQ879_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143624.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11769..12612
                     /locus_tag="VQ879_001489"
                     /pseudo
     CDS             11769..12612
                     /locus_tag="VQ879_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12680..14181
                     /locus_tag="VQ879_001490"
                     /pseudo
     CDS             12680..14181
                     /locus_tag="VQ879_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14193..14942
                     /locus_tag="VQ879_001491"
     CDS             14193..14942
                     /locus_tag="VQ879_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3143625.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14955..16127
                     /locus_tag="VQ879_001492"
     CDS             14955..16127
                     /locus_tag="VQ879_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3143626.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16522..17385
                     /locus_tag="VQ879_001493"
     CDS             16522..17385
                     /locus_tag="VQ879_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3143627.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17671..17904
                     /locus_tag="VQ879_001494"
     CDS             17671..17904
                     /locus_tag="VQ879_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143628.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17926..18603
                     /locus_tag="VQ879_001495"
     CDS             17926..18603
                     /locus_tag="VQ879_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143629.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18615..19280
                     /locus_tag="VQ879_001496"
     CDS             18615..19280
                     /locus_tag="VQ879_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143630.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19352..20578
                     /locus_tag="VQ879_001497"
     CDS             19352..20578
                     /locus_tag="VQ879_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3143631.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
BASE COUNT         6467 a         3224 c         4172 g         6807 t
ORIGIN      
        1 attattcttc atctggtgtg aggatcatcg ggatgatgat cggttcacgt tcggtatttt
       61 catagaggaa ggggcgaata gcgttgacaa tggcaccatt gacagattgc acgctagcat
      121 ccttattttt cagtgcgata cgaatggcat tgaagaggat acgctggctt tggcgaatca
      181 agtcgccaga ctctctcatg tagacaaagc ctcggctgag gatgtctgga ccagatagaa
      241 tcatctgcga tttgaagtca acagttgcga ctgccagaac gacaccgtct tcagatagat
      301 cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat acgatttcca tcgacataga
      361 tatcttgggc gttgaaatga cctgcgatac gagctgagtc agcagtaagg gcaagcacat
      421 cgccattgct catgataaag atattgtcct tctcaacacc agtatccact gctagtccag
      481 cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt ggcttaatca
      541 agcggagcat gagtttttgc tcttgctgac caccgtgtcc agatgtatgg atattgttca
      601 ctttaccgtg gataacttcg acaccagctt cagaaataat gttaatcagc ttgttgacgc
      661 tagtagtgtt tccagggatg ggactagaag agaagataac ggtatcgcct ggttggagtt
      721 gtacctgacg gtgggttccg ttggcgatac gagagagggc tgccataggt tcaccttgac
      781 tacctgtaca gaggatcaga atctcacctg caggatagtc tttgatttca tttggctcaa
      841 taaaggttcc cttaggagct ttgatgtagc caagatcgat tccgttgaca atggcctttt
      901 ccatagagcg accaaagacc gcaatcttgc gcccagtctt aacagcagct tccgttgctt
      961 gttggagacg gaagatattt gaggcgaagg atgcaaagat gatacgtccc tcgatacctt
     1021 ggataatctt catgatggac tggccgacaa ccttttcaga gttggtaaag gttggaacct
     1081 cagcattggt cgagtcagag agcaagcaaa gcactccatc ttcacctagg gctgccatac
     1141 ggtgcaagtc cgcaggttct ccaactggag taaagtcgaa cttaaagtca cctgtacaga
     1201 tgattttccc ttgaggagta tggatgacaa ttcccaaagg ttctggaata gagtgagtcg
     1261 ttctaaagaa agttgccttg agatttttaa aggtcaactc ggtgttgtgg ttgatttcgt
     1321 aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt cccacggatc aaagccaagg
     1381 caagcggtcc agcataaata gggacatttg cttgcttgag taggaacgga atcccaccaa
     1441 tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata ttgtctacga
     1501 tgtaagagta gtcaggaatg acatagtcga taccaagcaa gtcatcttct gggaatttaa
     1561 tcccagcatc gacgatgata atctcgtctt ggtattcaat tccgtaagtg tttttcccga
     1621 tttctcctag accaccgatg gcaaaaacgc cgacttcttc aggtttaaga gtgtaggcca
     1681 tattagaact ccgtaatttt gaaggcgcca gtttcttttt cgtaatcgag caatttgtca
     1741 gacaagagtt cgatatattc gatattgtac tctgggcgat tttcttcgac aagttggcga
     1801 gcagcgatac gaccctcaag ttctgagctg gcatcgatgt ctaggtaaag cgcgcgtgtt
     1861 gtttcacgac gtgggctacg ttcttttgtt tcttgataaa aaactttgta aatcatatag
     1921 ttcctttcta tttacaggtc agcttattcc aaacttttag cagagatttg cttgatttca
     1981 ttccattttg tgtctagatt gaccttgatt cgttacaatt atttcaatta taccacaaaa
     2041 tgaaaaatta gtaaaagacg gaaacgagaa agttagggga cgatttcttt ggtaagcgtt
     2101 tgcaaaaaca aagaaaatgt attatgttga taacggaagt gaaatttatt gcttgtcata
     2161 attccatata gattttaagt caaggaggtt gccctatgta taacttattt gcttttgcta
     2221 tcggagttcg tttgctagct tttatcgttt ttgttgcttg cgtttatgga ggaaatcttc
     2281 tatttgccaa actggaacga tgacaaacca agttcttgag gaaaattacc tttgtgactc
     2341 tctactcgct ttttctcctc ctcgtgacct atgtcgtttg gtttgtattt tactttggat
     2401 tgccctgctt atgctggggt tttttgtttg gggatgtaga gatagtagat ttacgacacg
     2461 aaaattccac cccatctatc aagatgaggt ggtctttgca tttttctaac atgacatgac
     2521 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
     2581 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
     2641 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
     2701 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
     2761 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
     2821 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatttttca tcatattaat
     2881 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
     2941 tagctttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
     3001 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
     3061 ttgaattttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
     3121 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
     3181 tcccatgtgc cagcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
     3241 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctcgctattt tagaggataa
     3301 gcagattctt gccgagatga cgattaatat taagaaaaat cacagtatta ccctcatgcc
     3361 tgccatcgat tttttgatgg caagtttgga ctggacaccc aaggatttgg accgaatcgt
     3421 ggtggctgaa gggccaggta gctacacagg cttgcgaatt gcggtagcca ctgccaagac
     3481 tttggctcat actctgaaca tcgagttagt tggtatgtct agcctcttgg ctctggtacc
     3541 ctaccaacaa gaaggcttgt tcgtctcttt gatggatgcg cgtcgcaaca atgtttatgc
     3601 aggattttat gaaaatgcta aacccgtcat gccagaagct cacttaccct ttgagcgagt
     3661 gattgagtta atcaagggtg ctagtcaggt tacctttgtc ggagaagttg gcccctttgt
     3721 tgagcagatt caagaatact tgccaaggac taatttcaaa gaaaccttgc caaatgcagc
     3781 taatctagct ctatgggcct gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
     3841 ctacctcaag cgtgtcgaag ctgaggaaaa ctggctcaag aatcacaccg agtctggcga
     3901 gtcttacatt aaacgcttat gatagaaatc aaacgaatcc aaaaacatcc tgacttggct
     3961 caagccatct acgctgttat gatagctgtt tacccagtca gtccttggac gctggaacaa
     4021 atccaagcag acctgtccca agaccagact tggtatgctt tggcttatga tggggcagaa
     4081 gtgattggat ttctagctgt gcaggagaat ctttttgaag cagaagtcct gcaaatcgct
     4141 gtcaaaggag cttatcagag tcaggggatt gcgtcagcct tgtttgctca attgccgaca
     4201 gacaaggaaa ttttcctcga agtcagacag tcaaatcaac gagcgcaagc attttacaag
     4261 aaagaaaaga tggcagttat cgctgagcga aaggcctact accatgaccc agtcgaggac
     4321 gccattatca tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
     4381 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
     4441 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
     4501 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
     4561 cgaagaggac gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
     4621 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
     4681 taatcacatg gctgggcacc tcatggcagc tcagagtgtg gagcctttgg agtttccctt
     4741 gctagccctt ttagtcagtg gtgggcacac agagttggtc tatgtttctg aggctggcga
     4801 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
     4861 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgatctgg ctcatcaggg
     4921 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
     4981 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
     5041 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
     5101 aaaaactaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
     5161 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
     5221 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
     5281 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
     5341 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctaca
     5401 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
     5461 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataacc ttaatcaaat
     5521 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
     5581 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
     5641 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
     5701 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
     5761 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
     5821 tgaagctatc ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
     5881 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
     5941 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
     6001 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
     6061 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
     6121 gaaatggttt cgaatcaccg catgagttcg tccgtctaaa attgcgagga tggatttgga
     6181 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
     6241 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
     6301 gacggtggaa gttgagcccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
     6361 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
     6421 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
     6481 atgcagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
     6541 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
     6601 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
     6661 ttccaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
     6721 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
     6781 tataattcct ggggtgggat tacccactac agaaattata gagccaaagc attccaaagt
     6841 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
     6901 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
     6961 aaaactggag gattttttta tgtccccccc atcgtcccat cgactgttcc gtagctgccc
     7021 aataacggag tataatcagc tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc
     7081 gtaatttgac aatattattc tgagatgttt ttgatgtaag cccatatttt ctcaatggga
     7141 ttatactcgg gtgaataggt aggaagtggt aacagtctat gccctgctcc ttacacatgt
     7201 tcattctgtg aaaccttgca ttgtccataa tgataaggga tggtgtatct aaagtaggta
     7261 gtaagaattt ttggaagcaa gcttcgaaaa agtcactcgt catcgtatct ttataggtca
     7321 tcggagccat agtatattga aacaaaaaag ggcattagta cttctataac agtatcgcaa
     7381 tctctggtgt gcgttgtctc gatcttaatt caaataatta tatcttcttc cagagagact
     7441 aactgcctgc tcaaggctcg atcatattcg agataaaaat aggtctcaac ccctgtctca
     7501 taaatataaa taggagtcag gtagcttaag tgattcaatt ctttaaggaa ccgatttact
     7561 ttttctgggt cttgttcgca gtaggtacgg ctctttttta gactatatcc catagccttt
     7621 agagcgtaat gaatagttgt tggaggacag ttgaattcag cagctatttc agtcaaataa
     7681 gcatcgggat gagtttcaat atagattttt aatttatctc tatcaatttt ttcaattaat
     7741 agtggaagtt tttttgaagt tagtgtattg aaacgttttt atacagtgct aaaatttgaa
     7801 gtgtagtgca gatgtatttg taatagtatt atagcaattc tttggagaag gtcgagacaa
     7861 gataaaatag gtatctttga gatataagca tgatttacta taaaattatt gagttattca
     7921 taaaaatttc tctatcaaat atcataatgc gtcgtttaag gagatggtta caatgcaata
     7981 tagttgtgga aaaataaata ttaatatccc tgatggatat ggagacatta aggatatagt
     8041 gttttcggct catattatag ttaggtataa taatggacat tgtggaggta tagatccgca
     8101 tataattgga ctttgtaaaa agcagatcag aaggatgtct ctatatccta ttttgataat
     8161 cgtatctaga gattcaaagg ttattgatga ttataaaaat ttagatattg cctatgttga
     8221 ttgtactcaa tgttcaaata attttgaaac tgccttacac gttaaaaata ttttaaaatt
     8281 attaaaaatc caacttatac actgtcatgg ctactcaact aattattttt tatatatgtt
     8341 aaaaaaactt gacaagaatg gatttggaaa ggttaagaca gtgataacat gccatggatg
     8401 ggttgaatat aacttaaaaa agaaattctt gacttatttt gatttttgga catattctat
     8461 gggagatgct tttatttgtg tatctgaaac tatgaaaaaa agattggaga gtataataaa
     8521 aaaataagaa gatagttgca ataaataacg gaattaatgt atcaaatagc gatttagatg
     8581 tagtaggtgt tcaagacttt aaaaaagaat tttgtattcc aaataacaaa aaatcatttg
     8641 ttatgttgga aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa
     8701 attattttta gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc
     8761 tgctttgaaa gaaaaaattt gctatttgaa atgtagagat aatttcaggt tacttggtga
     8821 aatctatcca gtactatagt ttaccaaata tcggatttat tgtatattcc ttctgataca
     8881 gaaggaatat ctatgtgtgt tttagagtca atgtcacaag gaactccggt tttagctagt
     8941 aatgttggcg ggttaagtga aattattgaa catagggttg atggattttt atttgagaag
     9001 gaagatgttg agggagtgtg tgcttgtgct aattttttac tcaatgattc tgagtatttg
     9061 aaatatgtag gtgagaatag taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg
     9121 tttgtagaaa ccatgagagt atatgatgaa ttattagaga agagtagtca tggataggaa
     9181 tatagatcaa gaattagtaa gtattataat accaacacat aataggtatg aatctctgat
     9241 tagagctgtg aaaagttgtt tacatcaaag ttataaaaat atcgaagtta taattattga
     9301 tgataattat agtaatgtaa atttaagaaa taaaattatc catcaatttg gctataccaa
     9361 tcatagaatt aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat
     9421 aggtatcaaa aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat
     9481 gccagatcga attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc
     9541 tttagtttat agttatggaa taataattta tccaaatggt acacgagaag aggagaagac
     9601 cgattttgtt ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt
     9661 ttggttgtgt aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca
     9721 tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg
     9781 agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca
     9841 aaaaacaatt aatgcagatg aagaatatta taattactgt aggaaatatt ttaatttatt
     9901 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
     9961 actatttaat aggagacaaa tgcaaggctt taaaagtaat caagaaggca agagaagaaa
    10021 aaatttttaa cgaatttctt ttttaaaata tatgttatta tatcattttg gttttttcta
    10081 ttgtatatat gacaactatg ttcaattaaa atttagaaag tgagaaacta ttgtgtatac
    10141 tattataaaa tcaaatataa aaaaatttag tttattaacg atatttattg ttgctggtca
    10201 attattgcta atttatgcag caactattaa tgctctggtg ttgaatgaat taattgcgat
    10261 gaatttagag cggtttttga aattgtcaat ctaccaaatg attgtctggt gtgggataat
    10321 attccttgac tgggtagtga aaaattatca ggttgaagtg atccaagagt ttaatctaga
    10381 gattcgaaat agagttgcca cagacatctc taactctacc tatcaagaat ttcatagtaa
    10441 atcatcagga acatatcttt cgtggctaaa taatgatgtt cagactttaa atgatcaggc
    10501 ttttaaacaa ctttttttag taataaaagg aatttctggt actatatttg cagttgtgac
    10561 tcttaatcac tatcattggt cattgactgt agccaccttg ttttcattaa tgattatgct
    10621 acttgtacca aaaatctttg catcgaaaat gcgagaagtt agtctaaatt taactaacca
    10681 aaatgaagct tttttaaaat ctagtgagac tatattgaat ggatttgatg tgttagcgtc
    10741 cttgaatctt ttatatgtat tgcctaagaa aattaaagaa gcaggaattt tattaaagat
    10801 ggttatacaa agaaagacaa ctgtagaaac gttagcaggc gctattagct tctttctcaa
    10861 tatttttttt cagatatctc tcgttttttt aacaggctat cttgcaataa aaggaatagt
    10921 gaaaattggt actattgaag caataggagc actaacaggt gttattttta cagcgctagg
    10981 tgaattagga ggtcaattat cctctattat tggtacgaag cctatttttt taaaattgta
    11041 ttcaattaat ccaattgagt caaataaaat gaatgatatc gaaccaaatg aggtgaatag
    11101 agattttccg ttatatgaag caaaaaatat ttgctataag tatggagata aagaaatatt
    11161 aaaaaactta aatttttgtt ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg
    11221 aagcgggaaa tctacattat taaaattatt gaatggcttt ttgagagatt atagtggaga
    11281 attgcgattc tgcggggatg atataaaaaa aacctcctat ttaaatatgg tttcgaatgt
    11341 tctatatgta gatcaaaaag cttatttgtt tgaaggtacg attagagata atattttatt
    11401 ggaagaaaat tatactgatg aagaaatact acagtcttta gagcaagttg gtttgagtgt
    11461 aaaagatttt cctaataaca ttttagatta ttatgttggt gatgatggga gattactgtc
    11521 aggagggcag aaacaaaaaa ttactttagc tagagggcta attagaaata agaaaatagt
    11581 attaattgac gagggaactt ctgctatcga taggagaact tcgttagcga ttgaacgtaa
    11641 gatattagat agagaggatt tgactgtcat tattgttacc catgctccgc atccggaact
    11701 taaacaatat tttactaaga tatatcaatt tccaaaggat tttatttaag aatatagggg
    11761 agggaaacat gagattctat tgtgaagctt atgaggtaat tactgaagag aaaaaagtat
    11821 actttaatga tattgagtta gaagttaagt attcctctgt cgaagaattg tttataatat
    11881 gtgagaaatt attagataag aaaaaagtat cattttttta tgtatatgag aaacccttaa
    11941 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaata tcccaatctt
    12001 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    12061 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    12121 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    12181 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    12241 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    12301 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    12361 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    12421 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    12481 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    12541 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    12601 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    12661 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    12721 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    12781 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    12841 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    12901 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    12961 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    13021 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    13081 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    13141 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    13201 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    13261 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    13321 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    13381 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    13441 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    13501 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    13561 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    13621 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    13681 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    13741 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    13801 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    13861 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    13921 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    13981 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    14041 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    14101 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    14161 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    14221 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    14281 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    14341 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    14401 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    14461 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    14521 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    14581 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    14641 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    14701 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    14761 taaaaatgta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    14821 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    14881 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    14941 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    15001 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    15061 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    15121 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    15181 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    15241 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    15301 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    15361 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    15421 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    15481 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    15541 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    15601 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    15661 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    15721 gtcttcccaa agatactaaa caattaaaaa aagaatttat agaaataaat gccccagtga
    15781 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    15841 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    15901 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    15961 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    16021 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg gaccttgaag
    16081 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    16141 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    16201 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    16261 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    16321 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    16381 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    16441 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    16501 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    16561 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    16621 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    16681 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    16741 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    16801 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    16861 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    16921 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    16981 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    17041 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    17101 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    17161 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    17221 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    17281 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    17341 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    17401 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    17461 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    17521 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    17581 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    17641 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    17701 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    17761 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    17821 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    17881 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    17941 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    18001 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    18061 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    18121 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    18181 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    18241 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    18301 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    18361 atgacaagtt tatctaaagt taatagatac tatcttgatg ttcttgtttc cgctgccata
    18421 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    18481 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    18541 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    18601 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    18661 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    18721 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    18781 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    18841 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    18901 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    18961 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    19021 ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga aagaaatggg
    19081 ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt aatcacggtt
    19141 gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca gtcttattta
    19201 gaatgacaaa gtcaatttat tggcctattg gactgcatat agtctacaat ggtattggtc
    19261 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt cttggggaaa
    19321 gattcccatt tgaatttaaa aaggagttgt aatgaaagta tttcttcaaa atagagattt
    19381 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    19441 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    19501 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    19561 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    19621 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgat
    19681 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    19741 tagaattatt gggcaagatc atctggcaga agctattgga tttaaacagt caactgttag
    19801 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggtattc tatccatcca
    19861 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    19921 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    19981 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    20041 cttggttttg tttattatct ctactagtca agcagtgata aatgttacag ttcctgtctc
    20101 tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat ctcttgcctt
    20161 gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg gctatctgca
    20221 acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt tgcttcttct
    20281 agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct tggatgcctt
    20341 tttcgcaggt gttctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    20401 gtcaatggga gcagttcaat cttctatcag tgccattacg gttgttttac ctagcttatt
    20461 tacaatatct ttggtaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    20521 attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa gtatttagtg
    20581 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    20641 caacagactt ttttctcttt tctgaatgtg
//
LOCUS       DAVBOU010000037        20667 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBOU010000037 DAVBOU010000000
VERSION     DAVBOU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.037"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            171..2153
                     /locus_tag="VQ879_001498"
     CDS             171..2153
                     /locus_tag="VQ879_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3143632.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2454..7757
                     /locus_tag="VQ879_001499"
     CDS             2454..7757
                     /locus_tag="VQ879_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3143633.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7924..10083)
                     /locus_tag="VQ879_001500"
     CDS             complement(7924..10083)
                     /locus_tag="VQ879_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3143634.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10080..10676)
                     /gene="recU"
                     /locus_tag="VQ879_001501"
     CDS             complement(10080..10676)
                     /gene="recU"
                     /locus_tag="VQ879_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3143635.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10742..11269
                     /locus_tag="VQ879_001502"
     CDS             10742..11269
                     /locus_tag="VQ879_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3143636.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11339..11668
                     /gene="gpsB"
                     /locus_tag="VQ879_001503"
     CDS             11339..11668
                     /gene="gpsB"
                     /locus_tag="VQ879_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3143637.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11689..12069
                     /gene="rnpB"
                     /locus_tag="VQ879_001504"
     ncRNA           11689..12069
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ879_001504"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12154..13311
                     /locus_tag="VQ879_001505"
     CDS             12154..13311
                     /locus_tag="VQ879_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3143638.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13324..14718
                     /gene="mapZ"
                     /locus_tag="VQ879_001506"
     CDS             13324..14718
                     /gene="mapZ"
                     /locus_tag="VQ879_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3143639.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14794..16218
                     /gene="gndA"
                     /locus_tag="VQ879_001507"
     CDS             14794..16218
                     /gene="gndA"
                     /locus_tag="VQ879_001507"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3143640.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16230..16919
                     /locus_tag="VQ879_001508"
     CDS             16230..16919
                     /locus_tag="VQ879_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143641.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17017..18036
                     /gene="cbpC"
                     /locus_tag="VQ879_001509"
     CDS             17017..18036
                     /gene="cbpC"
                     /locus_tag="VQ879_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3143642.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18154..19386)
                     /locus_tag="VQ879_001510"
     CDS             complement(18154..19386)
                     /locus_tag="VQ879_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3143643.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19546..20016)
                     /locus_tag="VQ879_001511"
     CDS             complement(19546..20016)
                     /locus_tag="VQ879_001511"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143644.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20183..20593)
                     /locus_tag="VQ879_001512"
     CDS             complement(20183..20593)
                     /locus_tag="VQ879_001512"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143645.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6425 a         3742 c         4634 g         5866 t
ORIGIN      
        1 agttctctag tctggagatt tttcaataga cttcgttatt gggcggttac gatattcata
       61 ttttttgcaa agatgttgtt tgaaaaataa ttttcaaaaa ttctgaaaat tctgttgaca
      121 tctttctgaa aagagtctat aatggagaga aagttttaaa ggagaaaatg atgaaaagtt
      181 caaaactatt tgcccttgcg ggcgtgacat tattggcggc gactacttta gctgcatgct
      241 ctggatcagg ttcaagtact aaaggtgaga agacattctc atacatttat gagacagacc
      301 ctgataacct caactatttg acaactgcta aggctgcgac agcaaatatt accagtaacg
      361 tggttgatgg tttgctagaa aatgatcgct acgggaactt tgtgccgtct atggctgagg
      421 attggtctgt atccaaggat ggattgactt acacttatac tatccgtaag gatgcaaaat
      481 ggtatacttc tgaaggtgaa gaatacgcgg cagtcaaagc tcaagacttt gtaacaggac
      541 taaaatatgc tgctgataaa aaatcagatg ctctttacct tgttcaagaa tcaatcaaag
      601 ggttggatgc ctatgtaaaa ggggaaatca aagatttctc acaagtagga attaaggctc
      661 tggatgaaca gacagttcag tacactttga acaaaccaga aagcttctgg aattctaaga
      721 caaccatggg tgtgcttgcg ccagttaatg aagagttttt gaattcaaaa ggagatgatt
      781 ttgccaaagc tacggatcca agtagtctct tgtataacgg tccttatttg ttgaaatcca
      841 ttgtgaccaa atcctctgtt gaatttgcga aaaatccgaa ctactgggat aaggacaatg
      901 tgcatgttga caaagttaaa ttgtcattct gggatggtca agataccagc aaacctgcag
      961 aaaactttaa agatggtagc cttacagcag ctcgtctcta tccaacaagt gcaagtttcg
     1021 cagagcttga gaagagtatg aaggacaata ttgtctatac tcaacaagac tctattacgt
     1081 atctagttgg tacaaatatt gaccgtcagt cctataaata cacatctaag accagcgacg
     1141 aacaaaaggc atcgactaaa aaggctctct taaacaagga tttccgtcag gctattgcct
     1201 ttggatttga ccgtacagcc tatgcctctc agttgaatgg acaaactgga gcaagtaaaa
     1261 tcttgcgtaa tctctttgtg ccaccaacat ttgttcaagc agatggtaaa aactttggcg
     1321 atatggtcaa agagaaattg gtcacttatg gggatgaatg gaaggatgtt aatcttgcag
     1381 attctcagga tggtctttac aatccagaaa aagccaaggc tgaatttgct aaagctaaat
     1441 cagccttaca agcagaagga gtccaattcc caattcattt ggatatgcca gttgaccaga
     1501 cagcaactac aaaagttcag cgcgtccaat ctatgaaaca atccttggaa gcaactttag
     1561 gagctgataa tgtcattatt gatatccaac aactacaaaa agacgaagta aacaatatta
     1621 catattttgc tgaaaatgct gctggcgaag attgggattt atcagataat gtcggttggg
     1681 gtccagactt tgccgatcca tcaacctacc ttgatatcat caaaccatct gtaggagaaa
     1741 gtactaaaac atatttaggg tttgactcag gggaagataa tgtagctgct aaaaaagtag
     1801 gtctatatga ctacgaaaaa ttggttactg aggctggtga tgaggctaca gatgttgcta
     1861 aacgctatga taaatacgct gcagcccaag cttggttgac agatagtgct ttgattattc
     1921 caactacatc tcgtacaggg cgtccaatct tgtctaagat ggtaccattt acaataccat
     1981 ttgcattgtc aggaaataaa ggtacaagtg aaccagtctt gtataaatac ttggaacttc
     2041 aagacaaggc agtcactgta gatgaatacc aaaaagctca ggaaaaatgg atgaaagaaa
     2101 aagaagagtc taataaaaag gctcaagaag atctcgcaaa acatgtgaaa taactgttgc
     2161 aaaatataag aaaggattta gtatttctct tgaatgctga atcctttttt acatttgtaa
     2221 agaaagcttc taaatgtact gacccccaaa agttggagcc tctttttgtc agaatagaga
     2281 aaatttttgt taattttact tgtttcctat tgctttctca gttattattt gttatattaa
     2341 aagtataatt attttttatt tatcagggtt aagcattgca ctttcagagg aaggagtatt
     2401 ttttaaaaag gaaatgtaaa cgcttgctaa aaaatgaaag gatttagaag tttatgaata
     2461 aaggattatt tgaaaaacgt tgtaaatata gtattcggaa attttcatta ggtgttgctt
     2521 ctgttatgat tggagctgca ttctttggga caagtccggt tcttgcagat agcgtgcagt
     2581 ctggttccac ggcgaactta ccagctgatt tagctactgc tcttgcaaca gcaaaagaga
     2641 atgatggacg tgattttgaa gcgcctaagg tgggagaaga ccaaggttct ccagaagtta
     2701 cagatggacc taagacagaa gaagaactat tagcacttga aaaagaaaaa ccggctgaag
     2761 aaaaaccaaa agaggataaa cctgcagctg ctaaacctga aacacctaag acggtaaccc
     2821 ctgaatggaa aacggtagag aaaaaagaac aaaagggaac agtcactatc cgagaagaaa
     2881 aaggtgtccg ctacaaccaa ctatcctcaa ctgctcaaaa tgataacgca ggtaaaccag
     2941 ccctgtttga aaagaagggc ttgaccgttg atgccaatgg aaatgcaact gttgatttaa
     3001 ccttcaaaga tgattctgaa aagggcaaat cacgctttgg tgtcttcttg aaatttaaag
     3061 ataccaataa taatgttttt gtcggttatg acaaggatgg ctggttctgg gagtataaat
     3121 ctccaacaac tagcacttgg tatagaggta gtcgtgttgc tgctcctgaa acaggatcaa
     3181 caaaccgtct ctctatcact ctcaagtcag acggtcagct aaatgccagc aataacgatg
     3241 tcaatctctt tgacacagtg actctaccag ctgcggtcaa tgaccatctt aaaaatgaga
     3301 agaagatcct tctcaaggcg ggctcttatg acgatgagcg aacagttgtt agcgttaaaa
     3361 cggataacca agagggggta aaaacagagg atacccctgc tgaaaaagaa acaggtcctg
     3421 aagttgatga tagcaaggtg acttatgaca cgattcagtc taaggtcctc aaagcagtga
     3481 ttgaccaagc cttccctcgt gtcaaggaat acaccttgaa tggacatact ttgccaggac
     3541 aggtgcaaca gttcaaccaa gtctttatca ataaccaccg aatcacccct gaagtcactt
     3601 ataagaaaat caatgagaca acagcagagt acttgatgaa gcttcgcgat gatgctcact
     3661 taatcaatgc ggaaatgaca gtacgcttgc aagttgtgga caatcaattg cactttgatg
     3721 tgaccaagat tgtcaaccac aatcaagtca ctccaggtca aaagattgat gacgaaagaa
     3781 aactactttc ttctattagt ttcctcggca atgctttagt ctctgtttct agtgatcaaa
     3841 ctggtgctaa gtttgatggg gcaaccatgt caaacaatac gcatgtcagc ggagatgatc
     3901 atatcgatgt aaccaatcca atgaaggatt tggctaaggg ttacatgtat ggatttgttt
     3961 ctacagataa gcttgctgct ggtgtttgga gtaactctca aaacagctat ggtggtggtt
     4021 cgaatgactg gactcgtttg acagcttata aagaaacagt cggaaatgcc aactatgtag
     4081 gaatccacag ctctgaatgg caatgggaaa aagcttataa gggcattgtt ttcccagaat
     4141 acacgaagga acttccaagt gctaaggttg ttatcactga agatgccaat gcagacaaga
     4201 acgttgattg gcaagatggt gccattgctt atcgtagcat tatgaacaat cctcaaggtt
     4261 gggaaaaagt taaggatatc acagcttacc gtatcgcgat gaactttggt tctcaagcac
     4321 aaaacccatt ccttatgacc ttggatggta tcaagaaaat caatctccat acagatggtc
     4381 ttgggcaagg tgttctcctt aaaggatatg gtagcgaagg ccatgactct ggtcacttga
     4441 actatgctga tattggtaag cgtatcggtg gtgtcgaaga cttcaagacc ctaattgaga
     4501 aggctaagaa atatggagct catctaggta tccacgttaa cgcttcagaa acttatcctg
     4561 agtctaaata cttcaatgaa aaaattctcc gtaagaatcc agatggaagc tatagctatg
     4621 gttggaactg gctagatcaa ggtatcaaca ttgatgctgc ctatgaccta gctcatggtc
     4681 gtttggcacg ttgggaagat ttgaagaaaa aacttggtga cggtctcgac tttatctatg
     4741 tggacgtttg gggtaatggt caatcaggtg ataacggtgc ctgggctacc cacgttcttg
     4801 ctaaagaaat taacaaacaa ggctggcgct ttgcgatcga gtggggccat ggtggtgagt
     4861 acgactctac cttccatcac tgggcagctg acttgaccta cggtggctac accaataaag
     4921 gtatcaacag tgccatcacc cgctttatcc gtaaccacca aaaagatgct tgggtagggg
     4981 actacagaag ttatggtggt gcagccaact atccactgct aggtggctac agcatgaaag
     5041 actttgaagg ctggcaagga agaagtgact acaatggcta tgtgactaac ctctttgctc
     5101 atgacgtcat gactaagtac ttccaacact tcactgtaag taaatgggaa aatggtacac
     5161 cggtgactat gaccgataac ggtagcacct ataaatggac tccagaaatg cgagtggagt
     5221 tggtagatgc tgacaataat aaagtagttg taactcgtaa gtcaaatgat gtcaatagcc
     5281 cacaatatcg cgaacgtaca gtaacgctca acggacgtgt catccaagat ggttcagctt
     5341 acttgactcc ttggaactgg gatgcaaatg gtaagaaact ttctactgag aaggaaaaga
     5401 tgtactactt caatacgcag gccggtacaa caacttggac ccttccaagc gattgggcaa
     5461 agagcaaggt ttacctttac aagctaactg accaaggtaa gacagaagag caagaactaa
     5521 ctgtaaaaga tggtaaaatt accctagatc ttctagcaaa tcaaccatac gttctctatc
     5581 gttcgaaaca aaccaatcct gaaatgtcat ggagtgaagg catgcacatc tatgaccaag
     5641 gatttaatag cggtaccttg aaacattgga ccatttcagg cgatgcttct aaggcagaaa
     5701 ttgtcaagtc tcaaggggca aacgatatgc ttcgtattca aggaaacaaa gaaaaagtta
     5761 gtctcactca gaaattaact ggcttgaaac caaataccaa gtatgccgtt tatgtcggtg
     5821 tcgataaccg tagtaatgcc aaggcgatca tcactgtaaa cactggtgaa aaagaagtga
     5881 ctacttatac caataagtct ctcgctctca actatgttaa ggcctacgcc cacaatacac
     5941 gtcgtgacaa tgctacagtt gacgatacaa gttacttcca aaacatgtac gccttcttta
     6001 caactggatc ggacgtctca aatgttactc tgacattgag tcgtgaagct ggtgatgaag
     6061 caacttactt tgatgaaatt cgtacctttg aaaacaattc aagcatgtac ggagacaagc
     6121 atgatacagg tcaaggaacc ttcaagcaag actttgaaaa tgttgctcag ggtatcttcc
     6181 catttgtagt gggtggtgtc gaaggtgtcg aagacaaccg cactcacttg tctgaaaaac
     6241 acgatccata tacacaacgt ggttggaacg gtaagaaagt tgatgatgtt atcgaaggaa
     6301 attggtcact caagacaaat ggactagtga gccgtcgtaa cttggtttac caaactattc
     6361 cgcaaaactt ccgttttgaa gcaggtaaga cctaccgtgt aacctttgaa tacgaagcag
     6421 gttcagacaa tacctatgct tttgtagtcg gtaagggaga attccagtca ggtcgtcgtg
     6481 gtactcaagc aagcaacttg gaaatgcatg aattgccaaa tacttggaca gattctaaga
     6541 aagccaagaa ggcaaccttc ctcgtgacag gtgcagaaac aggggatact tgggtaggta
     6601 tctactcaac tggaaatgca agtaatactc gtggtgattc tggtggaaat gccaacttcc
     6661 gtggttataa cgacttcatg atggataatc ttcaaatcga agaaattacc ctaacaggta
     6721 atatgttgac agaaaatgct ctgaagaact acttgccaac ggttgccatg actaactaca
     6781 ccaaagagtc tatggatgct ttgaaagagg cggtctttaa ccttagtcag gccgatgatg
     6841 atatcagtgt ggaagaagcg cgtgcagaga ttgccaagat tgaaaccttg aagaatgctt
     6901 tggttcagaa gaaaacggct ttggtagcag atgactttgc aagtcttaca gctcctgctc
     6961 aggctcaaga aggtcttgca aatgcctttg atggaaactt atctagtcta tggcatacat
     7021 cttggaatgg tggagatgta ggcaagcctg caaccatggt cttgaaagaa ccaactgaaa
     7081 tcactggact tcgttatgtt ccacgtggat caggttcaaa tggtaacttg cgtgatgtga
     7141 aacttgttgt gacagatgag tctggcaagg agcatacctt tactgcaact gattggccag
     7201 ataacaataa gccaaaagac attgattttg gtaagacaat taaggctaag aaaattgtcc
     7261 ttacaggtac taagacttac ggagatggtg gcgataaata ccaatctgca gcggaactca
     7321 tctttactcg tccacaggta gcagaaacac ctcttgactt gtcaggctat gaagcagctt
     7381 tgactaaggc tcagaaatta acagacaaag acaatcaaga ggaagtagct agcgttcagg
     7441 caagcatgaa atatgcgacg gataaccatc tcttgacgga aagaatggtg gaatactttg
     7501 cagattatct caaccaatta aaagattctg ctacgaaacc agatgctcca actgtagaga
     7561 aacctgagtt taaacttagc tctttagctt ccgagcaagg taagacgcca gattataagc
     7621 aagaaatagc tagaccagaa acacctgaac aaatcttgcc agcaacaggt gagagtcaat
     7681 ctgacacagc cctcttccta gcaggtgtta gcctagccct atctgctctc tttgtagtaa
     7741 aaacgaagaa agactagtat ttagtaaaac ctcttaacaa gattacggaa gcagtctcta
     7801 tcttttccaa tgaggtttat agtacagaaa aagcctgaga agatgtcttc tcaggctttt
     7861 gttaagcaca taaatacaat agtgctatga aaaaatcacc cagaaaaatc tgggtgataa
     7921 atgttatggt tgtgctgatt gaggattctg attttgttga tcaggggttg tatttgattg
     7981 ttgcgtatta ttgttaggat tggtagtcgt actattattt gtgcttggag tggttgagct
     8041 agactgtgaa gttgaactat ctgatgatga gcttgaactt tcagttgatg ggggttgttg
     8101 tggagcaggt gagctccacg tagaacgagc accattttta aatacgaatt ctccatttct
     8161 gtagagcccc tctggtatat tccaatcctc tggattgctt ccttcagaca ggtaggtcat
     8221 catagagcgg taaactttgg cagcgaccgt aaggccattg cctacaagtg gtgtcagacg
     8281 gttagaatag cctgtccata cagccattga atatttacgc gtatagccag caaatagttc
     8341 atcaggtgct acaaattgag aggtcttgat gtggttttca atttcctcgt ctgtatagtt
     8401 agaggttcct gttttaccag cctgagggag ccaagcaaga taggcatttc gtccagttcc
     8461 ataactcaag actgttttca tcatgtcggt catcatatag gctgtcgttt ccttcatggc
     8521 acgagttccg acattagaga actctttttc actcccatca ctaaagacga ctttatggat
     8581 atacattggt ttatagtaag ttccaccatt tgcaaaggca gcgtaagcag cagccatctt
     8641 ttcactactt gctccatatt ttttgtctga ttcggttgtg ttacttgaaa tggcatttga
     8701 gtagtgaata cttgggtagt cgattccgag accatttagg aaagtcttgg cgcggttgag
     8761 tccgaccttg tttagagttt ccacggctgg gacgtttcgc gattgttgca gggcgtattg
     8821 caaggtgatg ttgccaaagt agcccctatc ccagttataa acaggagtat ttgtcccagg
     8881 gtagttatag ggctcatcgt gaacgatagt agcagttgaa tcgtagacac cgtactccaa
     8941 ggcaggagca tagtctgtga tcggtttcat agttgatccc cagtcgcggt ttgtttctac
     9001 tgcttggtta attccgaagg aaacattact tgactgatgg cgtgctccta gctgggcaat
     9061 gactttaccg ttagaaacat caacaatggt agaagcgact tgcaattcat cgtctggata
     9121 ggcaacgtat tcgtctgtat tgtaaatatc ccacagatgt ttttgagctt cttggtctac
     9181 atttgtgtag acatccatcc cagttgtgag caggttatag cctgtttctt cttcaacttg
     9241 attgatgact tccttgaggt aattatccat gtaagcaggg taattacttg ctgatttgag
     9301 actttgtagt ccatcagtaa ttggtgtatt gactgctttc tcatactgtt cagcagagat
     9361 gtagccttga tttttcattt cagataagac caagtttcgg cggtcttggg ctgcttctgg
     9421 atgtgaatag gggtcatatt ggtttggtgc ctgaggcatt ccagccagca aggctaactg
     9481 aggtaaactt aaattattga ggtctttacc atagtagttt tgagctgctg tctgcattcc
     9541 atagttccca ttagacatgt agaccttatt tatatagtag gtcaagattt cttgcttggt
     9601 tgctttttgt tctaactgaa tcgctaacca agcttcctga gccttacgag aaatagtctg
     9661 gtcggaagtc gaagttgaaa agtaagtcaa cttaatcaac tgttgagtga gagttgatcc
     9721 accttggagg gaattgcttt gcagattgcg caagaaagct cccaggatac ggatggtatc
     9781 aatccccctg tggtcgaaga agcgatggtc ttcgatagaa acgattgcct taaccaaatc
     9841 tgtgggaata tcattagctt gggcattgac gcggcgttca gaacccaagt cagcaatgag
     9901 ttgattttta ttgtcgtaga ttttactaga agttgttgca actagtttac tctcggatag
     9961 gctaggagcc ttgctaacgt agtagaaaaa aactcctccg cctaagacaa tggctgcgat
    10021 aaccaagctt aagaagctaa tgctcagata cttgattagg cgcagaatcg ttggtttgtt
    10081 catcttgttt taccacctaa taaatgttct ttgataacat tgagataagg aatttgaggg
    10141 aaggcaccag ccttgatttc atatccatat tctcgaatat attcaagtgg cattgatttt
    10201 tgtctcttat cttgatgata gaagcgaatc aaatcgaatg ccggcaataa gtaggtttct
    10261 tgctgagaag aaaagtgaag aaggacaaag cagattcctt gttgggcaag gacttgttcc
    10321 atatgctgaa tctgatgtgg atgaaaattt ttcatcggaa tcgcacgttt ttgttttgtt
    10381 tccttgactt caaagtcgat gtaatatcca ttataaacgc cagaatagtc cgtcgttgaa
    10441 gcttgtcgaa aataggcttc aacaatcttg gcacgacttc gttgtggata gtccacttgt
    10501 acgatttgaa taggagttgg tttcttatgt ataacagcca agccctgaga caaatagtag
    10561 tcgttggtag cattgatcat cttttcaaaa gacattcctc gatttgcgaa atttttgggt
    10621 tgagaaagag atgtttgtct tttttgtgat gaaactttat gtggatagtt gaccataatt
    10681 ctccttattg gtacaataac atcactttat tataccataa tttgcacaga aagggttaaa
    10741 aatggctaca gctttggttt taggctattc tgcttttgat ttgggtttat tttctgataa
    10801 ggatcctcgt cttaaattga ttaaaaaagc gatacgtaaa gatttagagg ctatggcagc
    10861 agatggggtg tcttggcttg tgtttacagg gagtttgggt tttgaatatt gggttttaga
    10921 ggttgctcag gagatgaaaa ccgaatacgg tttccagttg gccaccattt ttgcttttga
    10981 aacccatggg gaaaattgga atgaaggcaa tcagatgaaa ctgagtcgct ttaagcaggt
    11041 agactttgtc aaatatgctt atcctcgcta tgaacacaag gggcagttaa gagattacca
    11101 gcagtttttg ctggaaaaca cgactagttc ctatcttttt tatgatgaag aaaatgaaac
    11161 aaaactagct tatttttacc aaaagatgaa aaatcaagag gactatttta taaagagatt
    11221 aacatttgat gaattaaatg aacttgctga aaatttttcc gaaaattgaa gctttgacct
    11281 tgatttttgt ttgccttttt ttatataata atactagcaa gcgagaatgg agagagacat
    11341 ggcaagtatt attttttcag cgaaagatat ttttgaacaa gagtttggac gtgaagtccg
    11401 tggctataat aaagtagaag ttgacgagtt tttagacgat gtcatcaagg actatgaaac
    11461 ctatgctgcc ttggtcaagt cacttcgtca ggaaattgcg gatttgaagg aagaattaac
    11521 tcgtaaaccg aaaccttcac cagttcaagc agaacccctt gaagcggcaa ttacaagttc
    11581 tatgacgaat tttgatattt tgaaacgcct gaatagattg gaaaaagaag tttttggtaa
    11641 acaaatttta gataactcag atttttaagt agttatttga gatgtgcaat ttttggataa
    11701 tcgcgtgagg agaattgctt ctcatgagga aagtccatgc tagcacaggc tgtgatgcct
    11761 gtagtgtttg tgctaggcga aaccataagc ctagggacga gaaatcgtta cggcagttga
    11821 aatggctaag tccttggata ggccagagta ggcttgaaag tgccacagtg acggagtctt
    11881 tctggaaaca gagagagtgg aacgcggtaa acccctcaag ctagcaaccc aaattttggt
    11941 cggggcatgg agtacgcgga aacgaacgta gtattctgac tgctatcagc tagagctgtt
    12001 agtggtagac agatgattat cgaaggaagt ggtcctagtc acttctggaa caaaacatgg
    12061 cttatagaaa attgcatata ggttggggct gagaaatttt ctcaacctca ttttttaaag
    12121 tggacatata gaaaggtctt gcaagactgt aacatgaaaa aagaatttaa tttaattgca
    12181 actgtggcag cagggcttga ggctgtcgtt ggtcgtgaag tgcgagagtt gggctacgat
    12241 tgtcaggttg aaaatggacg tgttcgtttt caaggagacg tgagagctat tatcgaaacc
    12301 aacctttggc ttcgggcagc agatcgtatc aaaattatcg taggaacgtt cccagctaag
    12361 acttttgaag agctatttca gggagttttc gctttagatt gggaaaatta tttaccactt
    12421 ggagctcggt tcccgatttc aaaagctaaa tgtgttaagt ccaaacttca caatgagccc
    12481 agtgttcagg ctatttctaa gaaagctgtt gtcaagaaat tgcagaaaca ctatgctcgc
    12541 ccagaagggg ttcctctgat ggagaatggc ccagagttta agattgaggt ctctattctc
    12601 aaagatgtgg caactgtcat gattgatacg accgggtcta gcctctttaa acgtggttat
    12661 cgtaccgaaa aaggtggcgc tcctatcaag gaaaatatgg cagcagccat tttacaactt
    12721 tctaactggt atccagacaa gcctttgatt gatccgacct gtggttcggg gactttctgt
    12781 attgaggcag ttatgattgc tagaaagatg gcgccaggtc ttcgtcgctc ttttgcattt
    12841 gaggaatgga actggatcag cgatcgcttg attcaagaag tgcgcacaga agcggctaaa
    12901 aaagtagaac gtgagcttga gttggatatc atgggctgtg atattgatgc tcgcatggtg
    12961 gaaattgcta aggccaatgc tcaggcagct ggtgttgcag gagacattac ttttaagcag
    13021 atgcgcgtgc aggatttacg ttccgataaa atcaatggag taatcatttc caatccgcct
    13081 tatggtgaac gtttgtcaga tgatgcaggg gtgaccaagc tctatgctga gatggggcaa
    13141 gtatttgcac cgctgaaaac ttggagcaaa tttatcctga ctagtgatga agcttttgaa
    13201 agcaagtatg gtagccaagc agataagaag cgtaagttat acaacggaac cttgaaagtg
    13261 gatctatatc aatattttgg tcagcgtgtc aaacggcaag aggtaaaata gaaagggata
    13321 ctcatgagta aaaaaagacg aaatcgtcat aaaaaagaag gtcaagaacc gcaatttgat
    13381 tttgatgaag caaaagagct aacagttggt caagctattc gtaaaaatga agaagtggaa
    13441 gcaggagtct tgcctgagga ttccattttg gacaagtatg ttaagcaaca cagagatgaa
    13501 attgaggcgg ataagtttgc gactcgtcaa tacaaaaaag aggagttcgt tgaaactcag
    13561 agtctggatg atttaattca agagatgcgt gaggctgtag agaagtcaga agcttcttcg
    13621 gaggaagttc catcttctga agacatctta ctacccttgc ctctggacga tgaggagcaa
    13681 ggcttggatc ctctattgct agatgatgaa aatccaacag aaatgactga agaagtggaa
    13741 gaggagcaaa acctttctcg tctggatcaa gaggactcag aaaagaaaag taaaaaaggc
    13801 tttattttga ccgttttggc gcttgtatca gtaattattt gtgtcagtgc ttattatgtc
    13861 taccgtcaag tggctcgttc gaccaaggaa attgaaactt ctcaatcaac tacagccaat
    13921 caatcagatg tggatgattt taatacactt tatgacgcct tttacacaga tagcaataaa
    13981 acggctttga aaaatagcca gtttgataaa ctgagtcaac tcaaaacctt gcttgataaa
    14041 ctggaaggta gtcgtgaaca tacgcttgcc aaatctaaat atgatagtct agcaacgcaa
    14101 atcaaggcta ttcaagatgt caatgcacaa tttgaaaaac cagctattgt ggatggtgtg
    14161 ttggatacca atgccaaagc caaatcggat gctaaattta cggatattaa aactggaaat
    14221 acggagcttg ataaagtgct agataaggct atcagtcttg gtaagagcca gcaaacaagt
    14281 acttctagct caagttcaag tcaaactagc agctcaagct ctagtcaagc aagttcaaat
    14341 acgactagtg agccaaaacc aagtagttca aatgagacta gaagtagtcg cagtgaagtc
    14401 aatatgggtc tctcgagtgc aggggttgct gttcaaagaa gtgccagtcg tgttgcctat
    14461 aatcagtctg ctattgatga tagtaataac tctgcctggg attttgcgga tggtgtcttg
    14521 gaacaaattc tagcgacttc acgttcacgt ggctatatca ctggagacca atatatcctt
    14581 gaacgtgtca atatcgttaa cggcaatggt tattacaacc tctataagcc agatggaacc
    14641 tatctcttta cccttaactg taagacaggc tactttgtcg gaaatggcgc tggtcatgcg
    14701 gatgacttgg actactaagc agtcgttaca aaattctttc ttttcaaaag taaaaatgat
    14761 aaaataaaac aaatgaaaca agaggagtgt caaatgacaa aagctaactt tggtgtcgta
    14821 ggtatggccg taatgggtcg taaccttgcc cttaatattg aatcacgtgg ttacacagtt
    14881 gctatctaca accgtagtaa agaaaaaacg gaagatgtga ttgcttgcca tcctgaaaag
    14941 aactttgtac caagctatga cgttgaaagt tttgtaaact caatcgaaaa acctcgtcgt
    15001 atcatgctga tggttcaagc tggacctggt acagatgcta ctatccaagc ccttcttcca
    15061 caccttgaca agggtgatat cttgattgac ggtggaaata ctttctacaa agataccatc
    15121 cgtcgtaatg aagaattggc aaactcaggt atcaacttta tcggtactgg agtttctggt
    15181 ggtgaaaaag gtgcccttga aggtccttct atcatgcctg gtggacaaaa agaggcctac
    15241 gaattggttg cggatgttct tgaagaaatc tcagctaaag caccagaaga tggcaagcca
    15301 tgtgtgactt acatcggtcc tgatggagct ggtcactatg tgaaaatggt tcacaatggt
    15361 attgagtacg gtgatatgca attgatcgca gaaagctatg acttgatgca acacttgcta
    15421 ggcctttctg cagaggatat ggctgaaatc tttactgagt ggaacaaggg tgaattagac
    15481 agctacttga tcgaaatcac agctgatatc ttgagccgta aagacgatga aggccaagat
    15541 ggaccaatcg tagactacat ccttgatgct gcaggtaaca agggaactgg taaatggacg
    15601 agccaatcat ctcttgacct tggtgtacca ttgtcactga ttactgagtc agtgtttgca
    15661 cgctacattt caacttacaa ggaagaacgt gtacatgcta gcaaggtgct tccaaaacca
    15721 gctgccttca actttgaagg agacaaggct gaattgattg aaaaaatccg tcaagccctt
    15781 tacttctcaa aaatcatttc atacgcacaa ggatttgctc aattgcgtgt agcctctaaa
    15841 gaaaacaact ggaacttgcc atttgcagat atcgcatcta tctggcgtga tggctgtatc
    15901 atccgttctc gtttcttgca aaagattaca gatgcttaca accgcgatgc agatcttgcc
    15961 aaccttcttt tggacgagta cttcttggat gttactgcta agtatcaaca agcagtgcgt
    16021 gatatcgtag ctcttgcggt tcaagctggt gtgccagtgc caactttctc agcagctatt
    16081 acttactttg atagctaccg ttcagctgac cttccagcta acttgatcca agcacaacgt
    16141 gactactttg gtgctcacac ttaccaacgt aaagacaaag aaggaacctt ccactactct
    16201 tggtatgacg aaaaataagt aggtcagcca tggggaaacg gattttatta cttgagaaag
    16261 aacgaaatct agctcatttt ttaagtttgg aactccagaa agagcagtat cgggttgatc
    16321 tggtagagga ggggcaaaaa gccctctcca tggctcttca gacagactat gatttgatgt
    16381 tattgaacgt taatctggga gatatgatgg ctcaggattt tgcagaaaaa ttgagtcgaa
    16441 ctaaacctgc ctcagtcatc atgattttag atcattggga agacttgcaa gaagagctgg
    16501 aagttgttca gcgttttgca gtttcataca tttataagcc agtccttatc gaaaatctgg
    16561 tagcgcgtat ttcggcgatc ttccgaggtc gggacttcat tgatcaacac tgcagtctga
    16621 tgaaagttcc aaggacctac cgcaatctta ggatagatgt tgaacatcac acggtttatc
    16681 gtggtgaaga gatgattgct ctgacccgcc gtgagtatga ccttttggcg acacttatgg
    16741 gaagcaagaa agtattgact cgtgagcaat tgttggaaag tgtttggaag tatgaaagtg
    16801 cgaccgagac aaatatcgta gatgtctata tccgctatct acggagcaag cttgatgtta
    16861 aaggccaaaa aagctacatt aaaaccgtgc gtggtgttgg atataccatg caagaataga
    16921 taagcagttg cagttgtgta actgcttttt tgaggagttt ttatatattg acatgcagtc
    16981 gggtctttgc tacaatcgtt ttaggaggat atatagatga aacttttgaa aaaaatgatg
    17041 caagttctac tagcagtctt tttctttggt ttgctagcta caaatacggt atttgcgaat
    17101 accacaggtg gccgatttgt tgataaggat aatagaaaat attatgtaaa agatgatcat
    17161 aaagcaatct attggcataa aatagacggt aaaacttact attttggtga tattggagag
    17221 atggttgtcg gttggcaata cttagaaatt cctggaacag gttatcgtga taatttattc
    17281 gataaccaac cagttaatga aattggcctt caggagaagt ggtactattt tggacaagat
    17341 ggtgctttgc tagaacaaac agataaacaa gtactagagg caaaaacgtc tgaaaataca
    17401 ggaaaagtat acggtgaaca atatcctcta tctgctgaaa agagaactta ttattttgat
    17461 aataattatg ctgtaaagac aggctggatt tatgaagacg gcaattggta ttatttaaat
    17521 aagctaggaa attttggcga tgattcttac aatccactac caattagtga agttgctaag
    17581 ggttggactc aagattttca tgttactatt gacattgata gaagcaaacc tgctccatgg
    17641 tactacctag acccagaaac tggcattatg cgaacaggat ggcaatatct aggtaataac
    17701 tggtactacc tccgttcatc aggagcaatg gccactggct ggtatcagga aggtaccact
    17761 tggtattatt tagaccagcc aaatggcgat atgaaaacag gttggcaaaa ccttgggaac
    17821 aaatggtact atctccgttc atcaggagct atggcaactg gttggtatca agatggttca
    17881 acttggtact acctaaatgc aggtaatgga gacatgaaga caggttggtt ccaggtcaat
    17941 ggcaactggt actatgctta tagctcaggt gctttggcag tgaatacgac cgtagatggc
    18001 tattctgtca actataatgg cgaatgggtt cggtaatgac agggcgctta taattatatt
    18061 agaacactcg cttaatcaaa gaagtgactt tgttgtactt gacctgacga ttggggagat
    18121 taaaagcatg tgaaatctac acatgctttt tcgttagtta tgagtgttga acttgactaa
    18181 ccattgacaa aagataagag caattaaaat aagatacaaa aatatcaatg ctaactgcac
    18241 cgaaacgccc gatgctatgg atagggctaa tagggagagc agggacgggg cgagaatgtc
    18301 cactgtgctc agagcagagc ccaccgtccc catcttgtca ctggggatat aggcaaagac
    18361 agctgcttgt aggcgagggc tgagaatgcc gataatcgta gaactgatga aactggtcat
    18421 gaaaattacg atataggctt gacaaaggat actagttatt agagccaata gggaaatctc
    18481 acagaaaacc aagaggtgcg tgaaacggat atttttaaat agattactgc tggtcatatt
    18541 gccaaggata gctccacaag acatgatgat ggagagcagg gcgaggagtt gcccaatgct
    18601 cagttgtgct agtgtctgtt ggatgaagcg gagggcaatc agccgagggg acacatccaa
    18661 gatggcaatc atactggtcg tcagaaacag tagtatgacg gtatctttta acttcagtag
    18721 cacagccagc gactgtttaa gatgttgaaa atatttctta aaactcagtg ctgtatgtga
    18781 catttcaatc cttttttcaa cctcatacaa ggtatgtcga ataacataca ggcccaaaaa
    18841 ggcaatgaca aaagtcagag tgttgataag ggaaatagtt tgaatactta taacattgat
    18901 aaggaatgcg ccagccagat tggcgacaat gcggacaacc ctcatcagag actgcctgaa
    18961 ccccatggca tcatgcaggt cgtccttaat tacactgatg tagagggcgt tcatcatgta
    19021 ggcagacagg tagctcaagg tgtcagagat gaggttgatg atgacaatca taatgactga
    19081 aactaatgaa aagggcgaca agacgagaaa tactgtcaaa atagcgtaga gcaggatttt
    19141 gattttggca atacagagtg cgtgtttgac tctattttct tgaaaatctc ctagaatccc
    19201 gagaaagagt tgcgatagta ggggaaccat ctctgaaatg gaaatcagta aaatcgctag
    19261 cggagcgaaa ttgtactgag ccacataatt gataatggcg aggtagaaaa tactgtcgcc
    19321 gaatgatgaa aaacagctgt ttagcagcaa ctgtctatat atgttgtttg tccaaaataa
    19381 tttcatacat ttctccttat gtctgcacat cgaatgggaa tttattattt aatagacacc
    19441 aatatacccc catgcttcct attccgaagt caaacaaatc tgctttacca ctatctcctt
    19501 gaaacatcag taaaccgtga tcatctcgtt cagaacatgc taaaattacc tgttggattt
    19561 tttcatcagt aatttgtttt gattgtagac agtggtttgt agtaagctag ttattccgtg
    19621 gcaatatcct gtcatcattt ttagatgatg gttaaaaaca aattcttgat atttactaat
    19681 aatatctttg tttccgtcac aatcgtacat acaaagatat aagattattc cggaaattcc
    19741 tttgcaccaa gaaagttgta aatttcctaa attttcagta ttagaagtaa ctttttctaa
    19801 taattttttt aattcagtat ggaatgtatg gagatcatta tagaacatag aaggttctaa
    19861 gactttagaa taggcaaata aagcatatgc aattccacaa tatccatgag caaagctata
    19921 gtctaaaatg ctttctttgg ctgtatctct ttgtaggaaa taatgataaa tttccccata
    19981 tactattgtg gatgaaagtt ttaagagtat tgtcattggt aacttgatag tattttatta
    20041 atgataatag gacaccagat tttcccaatg caaagtctat ttcctctaga gtatcataat
    20101 tctctattaa tttcttagcg gtgacgtttg ctaattgtag atagtattga tttttactga
    20161 tagaaaataa atgtaggagt aactatagat agcctgcacc accaaatagc agtgagtatt
    20221 gatattcata tgtgtgtgac gttctaattg tcactgcctt cttgatgata gagagtattt
    20281 tagaatccag ttctgggtgg tacaatttat ttagaggaaa cagtagtcca gctattccgt
    20341 gttggaatga taaattactt acgaaatttc caaattctgt tgaagaagtg atccttcctt
    20401 cagaatttac agttttatct agtaaaaatc gtagaacact attacattct gttttgtaat
    20461 catatttatg ttcctctatt tttttaattt tgactaaatt atttgtttga cttaaattta
    20521 gtagacattg taaccaaaat agttgctcat ctgtgagctg accttgagta tgtgatagtt
    20581 ctagtaattg aataggatcc tttagttaga ttcaatcaat ctataacaca acaacataat
    20641 aatactttta ggataacttg tcaaata
//
LOCUS       DAVBOU010000038        20118 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBOU010000038 DAVBOU010000000
VERSION     DAVBOU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20118
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.038"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ879_001513"
     CDS             638..952
                     /locus_tag="VQ879_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3143646.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ879_001514"
     CDS             968..1354
                     /locus_tag="VQ879_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3143647.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ879_001515"
     CDS             1383..2768
                     /locus_tag="VQ879_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3143648.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ879_001516"
     CDS             2771..2923
                     /locus_tag="VQ879_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3143649.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ879_001517"
     CDS             2946..4151
                     /locus_tag="VQ879_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3143650.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ879_001518"
     CDS             4194..4415
                     /locus_tag="VQ879_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143651.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ879_001519"
     CDS             4532..5029
                     /locus_tag="VQ879_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3143652.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ879_001520"
     CDS             5004..5510
                     /locus_tag="VQ879_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3143653.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ879_001521"
     CDS             5494..7941
                     /locus_tag="VQ879_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3143654.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10121
                     /locus_tag="VQ879_001522"
     CDS             7944..10121
                     /locus_tag="VQ879_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3143655.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            10118..11119
                     /locus_tag="VQ879_001523"
     CDS             10118..11119
                     /locus_tag="VQ879_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3143656.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11116..12051
                     /locus_tag="VQ879_001524"
     CDS             11116..12051
                     /locus_tag="VQ879_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3143657.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12296..12412
                     /locus_tag="VQ879_001525"
     CDS             12296..12412
                     /locus_tag="VQ879_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3143658.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ879_001526"
     CDS             12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ879_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3143659.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14466..14633
                     /locus_tag="VQ879_001527"
     CDS             14466..14633
                     /locus_tag="VQ879_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3143660.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14693..15046)
                     /locus_tag="VQ879_001528"
     CDS             complement(14693..15046)
                     /locus_tag="VQ879_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3143661.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15551..15973
                     /locus_tag="VQ879_001529"
     CDS             15551..15973
                     /locus_tag="VQ879_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3143662.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15970..16200
                     /locus_tag="VQ879_001530"
     CDS             15970..16200
                     /locus_tag="VQ879_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3143663.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16661..16864
                     /locus_tag="VQ879_001531"
     CDS             16661..16864
                     /locus_tag="VQ879_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3143664.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16946..18163
                     /locus_tag="VQ879_001532"
     CDS             16946..18163
                     /locus_tag="VQ879_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3143665.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18325..18927)
                     /locus_tag="VQ879_001533"
     CDS             complement(18325..18927)
                     /locus_tag="VQ879_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143666.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18930..19163)
                     /locus_tag="VQ879_001534"
     CDS             complement(18930..19163)
                     /locus_tag="VQ879_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3143667.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19176..19556)
                     /locus_tag="VQ879_001535"
     CDS             complement(19176..19556)
                     /locus_tag="VQ879_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143668.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19549..19998)
                     /locus_tag="VQ879_001536"
     CDS             complement(19549..19998)
                     /locus_tag="VQ879_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143669.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19982..>20118)
                     /locus_tag="VQ879_001537"
     CDS             complement(19982..>20118)
                     /locus_tag="VQ879_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3143670.1"
                     /translation="FEAARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDESAK
                     "
BASE COUNT         6588 a         3641 c         4065 g         5824 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgctggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga
     8881 ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat
     8941 ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta
     9001 tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac
     9061 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
     9121 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
     9181 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
     9241 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
     9301 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
     9361 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
     9421 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
     9481 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
     9541 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
     9601 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
     9661 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
     9721 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
     9781 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
     9841 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta
     9901 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
     9961 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
    10021 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
    10081 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
    10141 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
    10201 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
    10261 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
    10321 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
    10381 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
    10441 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
    10501 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
    10561 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
    10621 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
    10681 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
    10741 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
    10801 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
    10861 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
    10921 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
    10981 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
    11041 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
    11101 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
    11161 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
    11221 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
    11281 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
    11341 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
    11401 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
    11461 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
    11521 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
    11581 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
    11641 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
    11701 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
    11761 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
    11821 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa accaatcgga
    11881 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
    11941 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
    12001 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
    12061 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
    12121 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
    12181 atgcggcaag gtattcttaa ataaactgtc aatttgatag tggaaacaaa taattggatg
    12241 tcctttttta ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat
    12301 tctaaagtat ccggagaata tctgtatgct ttgtatgcct atggttatgc ataaaaatcc
    12361 cagtgataag agtatttatc actgggattt ttatgccctt ttgggctttt gaatggagga
    12421 aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcgg gaaaaactac
    12481 cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacag
    12541 aggtacaacg aaaacggata atacgctttt agaacgtcag agaggaatta caattcagac
    12601 ggcgataacc tcttttcagt ggaaaaatac taagataaac atcatagaca cgccaggaca
    12661 tatggatttt ttagcagaag tatatcgttc attatcagta ttagatgggg caattctact
    12721 gatttctgca aaagatggcg tacaagcaca aactcgtata ttgtttcatg cacttaggaa
    12781 aataggtatt cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc
    12841 aacggtttat caggatatta aagagaaact ttctgcggaa attgtaatca aacagaaggt
    12901 agaactgcat cctaatatgc gtgtaatgaa ctttaccgaa tctgaacaat gggatatggt
    12961 aatagaagga aatgattacc ttttggagaa atatacgtct gggaaattat tggaagcatt
    13021 agaactcgaa caagaggaaa gcataagatt tcataattgt tccctgttcc ctgtttatca
    13081 cggaagtgca aaaaacaata tagggattga taaccttata gaagtgatta cgaataaatt
    13141 ttattcatca acacatcgag gtcagtctga actttgcgga aaagttttca aaattgagta
    13201 ttcggaaaaa agacagcgtc ttgcatatat acgtctttat agtggcgtac tgcatttgcg
    13261 agattcggtt agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat
    13321 aaatggtgaa ttatgtaaaa tcgataaggc ttattccggg gaaattgtta ttttgcagaa
    13381 tgagtttttg aagttaaata gtgttcttgg agatacaaag ctattgccac agagagagag
    13441 aattgaaaat cccctccctc tgctgcaaac gactgttgaa ccgagcaaac ctcaacaaag
    13501 ggaaatgtta cttgatgcac ttttagaaat ctccgacagt gacccgcttc tgcgatatta
    13561 tgtggattct gcgacacatg aaatcatact ttctttctta gggaaagtac aaatggaagt
    13621 gacttgtgct ctgctgcaag aaaagtatca tgtggagata gaaataaaag agcctacagt
    13681 catttatatg gaaagaccgt taaaaaaagc agagtatacc attcacatcg aagttccacc
    13741 gaatcctttc tgggcttcca ttggtctatc tgtagcaccg cttccattag ggagcggagt
    13801 acagtatgag agctcggttt ctcttggata cttaaatcaa tcgtttcaaa atgcagttat
    13861 ggaggggata cgctatggct gtgaacaagg attgtatggt tggaatgtga cggactgtaa
    13921 aatctgtttt aagtatggct tatactatag ccctgttagt accccagcag attttcggat
    13981 gcttgctcct attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc
    14041 atatcttagt tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc
    14101 tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag
    14161 tggagaaatc cctgctcggt gtattcaaga atatcgtagt gatttaactt cctttacaaa
    14221 tggacgtagt gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt
    14281 ttgccagccc cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat
    14341 aacttagtgt attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat
    14401 tttttaataa agatttgaat taaagtgtaa aggaggagat agttattata aactacaagt
    14461 ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa gataagggaa gatactgaat
    14521 taaaaaaatt ccccctctat tgtccgaaat gcagacaaga aaatttaatt gaaataaagc
    14581 agttcaaagt aactgtgatt acagagccag acgcaaagac gcagagccga taaaatgaga
    14641 ttaatacaat ctcattttat cggctctttc cgttatgtat ggattctttt aattagtctt
    14701 cgatgtttct tgcttcgttg ataccgctgg ctaaagattc cattaaggat agttctttgt
    14761 ctgtaaagct atccatgtat ttctctatct gtaatcgtcg ggtgcttttt accaagttat
    14821 tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    14881 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    14941 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    15001 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    15061 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    15121 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    15181 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    15241 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    15301 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    15361 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    15421 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    15481 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    15541 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    15601 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    15661 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    15721 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    15781 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    15841 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    15901 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    15961 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    16021 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    16081 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    16141 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    16201 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    16261 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    16321 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    16381 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    16441 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    16501 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    16561 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    16621 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    16681 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    16741 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    16801 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    16861 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    16921 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    16981 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    17041 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    17101 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    17161 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    17221 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    17281 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    17341 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    17401 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    17461 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    17521 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    17581 ttatgatgaa attctgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    17641 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    17701 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    17761 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    17821 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    17881 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    17941 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    18001 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    18061 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    18121 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    18181 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    18241 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    18301 aaatataaaa agataattag aaatttatac tttgttttta ttaaaaagca gcaaactata
    18361 aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg atttatagcg
    18421 taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa tggttcctgg
    18481 atgatgagct aaggcaaata aaacacttgt caaagcaact cgaatatcta attttctaac
    18541 caagttccat aaaatttctc tatacaaaaa ttcttcaacc atactcgcat tgattaagaa
    18601 caataaaaat gaaaaccaag gaacttgatg ttgaagccca attaagtttg cttgatttgt
    18661 gctttcttga gcatgaatca gactaaaata tagactgata atcagtaggc taacgaatcc
    18721 aataccaatc cactttatcc tagtttccat attgaccttg gccacttgtt ttcgttgacc
    18781 atacatccat aaaaaagaaa tgagcgacgc tccatagata atctgtagta tagttaactc
    18841 accgatacaa agaaatttca gtaagtataa ggataccaat aggacattta cttgttggaa
    18901 tatataaact ggaattattc ttttcatagt tacctccgaa ataaatcttc ataatctaaa
    18961 tctaatacct gcacaatcct ctctacccat ggactttgag gcattcgttg ttccatcttg
    19021 tagtgacgaa tcttttgata caaacgattc aattcacttg gatagtgaaa ctctcccgca
    19081 aacatttttc tggttaactc aatccagctg atatttcttt cagccaaaat aatggacaag
    19141 ttctcccaaa atcgttcagc catattgctt ctcctttagt tagataaata atgtgtttgt
    19201 gccatgtaaa tcaattgttt cgtatctctt ggtaataaag ccctagcttc ctccaaattt
    19261 agatttggat aaactcgctt atttgaaacc gcaagaggaa gtctgatggt tagttcagga
    19321 ttttttaata tcatttcaat gaaatccgtt agtcttaaat tgtcacggtt cttaaatcgt
    19381 aataaattag gagataaaaa ctcaaaacaa tctgaagaat agctcatcat ctcaattaat
    19441 ttatcccttg tcatttcaga aatcgaatga caggatacct caatgccata gttttggaag
    19501 aattctaaaa gaagttgatt tctatggtta tttttactta gatagagatc aatcatgtga
    19561 gacctcccaa agattcggtt ccatttgata ttctgagacg attaaggaat ctaataaatt
    19621 ggagaagtta attgatttct tgtcttcatc ataagctttt acagttactt gggttgtaag
    19681 tattccctct tttccctcgg ctcgatagcc ttgcccatat aaaacaaaaa caagattatg
    19741 attatcatct ataaaggcat cagctccgtt ctttatatcc tgactttcaa ggaattccat
    19801 aatgttttga agataggatt cgtaaaatag ggggtaattg tgttttttat ggtaataatc
    19861 taaaaatgtc acctcaaact cacatggata attgggcatc aaaaatattt gttcatccaa
    19921 ctgcatcatt tctgcatcat gtaattctgt ttctaattca tcacaatata gtattgactc
    19981 tttatttagc gctttcatct ttttcctcta tttcttttaa tttttttgcg attgcggcaa
    20041 tcacaggaac agttacacta ttaccagctt gtttatagag ctgactatta ctagagactt
    20101 ttctagcagc ttcaaaag
//
LOCUS       DAVBOU010000039        19814 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBOU010000039 DAVBOU010000000
VERSION     DAVBOU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.039"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..261)
                     /locus_tag="VQ879_001538"
                     /pseudo
     CDS             complement(1..261)
                     /locus_tag="VQ879_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            386..844
                     /locus_tag="VQ879_001539"
     CDS             386..844
                     /locus_tag="VQ879_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3143671.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            857..1465
                     /locus_tag="VQ879_001540"
     CDS             857..1465
                     /locus_tag="VQ879_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143672.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1536..1868
                     /locus_tag="VQ879_001541"
     CDS             1536..1868
                     /locus_tag="VQ879_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143673.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1879..3294
                     /gene="ply"
                     /locus_tag="VQ879_001542"
     CDS             1879..3294
                     /gene="ply"
                     /locus_tag="VQ879_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3143674.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4175..4891
                     /locus_tag="VQ879_001543"
     CDS             4175..4891
                     /locus_tag="VQ879_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3143675.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5015..5484
                     /locus_tag="VQ879_001544"
                     /pseudo
     CDS             5015..5484
                     /locus_tag="VQ879_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5501..6322
                     /locus_tag="VQ879_001545"
                     /pseudo
     CDS             5501..6322
                     /locus_tag="VQ879_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            6329..7300
                     /locus_tag="VQ879_001546"
     CDS             6329..7300
                     /locus_tag="VQ879_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3143676.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            7426..7788
                     /locus_tag="VQ879_001547"
     CDS             7426..7788
                     /locus_tag="VQ879_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3143677.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7785..8288
                     /locus_tag="VQ879_001548"
     CDS             7785..8288
                     /locus_tag="VQ879_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3143678.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8402..8848
                     /locus_tag="VQ879_001549"
     CDS             8402..8848
                     /locus_tag="VQ879_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143679.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8853..9527
                     /locus_tag="VQ879_001550"
     CDS             8853..9527
                     /locus_tag="VQ879_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143680.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            9688..9879
                     /locus_tag="VQ879_001551"
     CDS             9688..9879
                     /locus_tag="VQ879_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3143681.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            10164..10463
                     /locus_tag="VQ879_001552"
     CDS             10164..10463
                     /locus_tag="VQ879_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3143682.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10460..10777
                     /locus_tag="VQ879_001553"
     CDS             10460..10777
                     /locus_tag="VQ879_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3143683.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            10793..11419
                     /locus_tag="VQ879_001554"
     CDS             10793..11419
                     /locus_tag="VQ879_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3143684.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11452..12213
                     /locus_tag="VQ879_001555"
     CDS             11452..12213
                     /locus_tag="VQ879_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3143685.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12291..12686
                     /locus_tag="VQ879_001556"
     CDS             12291..12686
                     /locus_tag="VQ879_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3143686.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            12956..13240
                     /gene="groES"
                     /locus_tag="VQ879_001557"
     CDS             12956..13240
                     /gene="groES"
                     /locus_tag="VQ879_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3143687.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13256..14878
                     /gene="groL"
                     /locus_tag="VQ879_001558"
     CDS             13256..14878
                     /gene="groL"
                     /locus_tag="VQ879_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3143688.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            15016..15771
                     /locus_tag="VQ879_001559"
                     /pseudo
     CDS             15016..15771
                     /locus_tag="VQ879_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(16212..16745)
                     /locus_tag="VQ879_001560"
     CDS             complement(16212..16745)
                     /locus_tag="VQ879_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3143689.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(16834..17610)
                     /gene="recX"
                     /locus_tag="VQ879_001561"
     CDS             complement(16834..17610)
                     /gene="recX"
                     /locus_tag="VQ879_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3143690.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(17620..18396)
                     /locus_tag="VQ879_001562"
     CDS             complement(17620..18396)
                     /locus_tag="VQ879_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3143691.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            18453..19808
                     /gene="rlmD"
                     /locus_tag="VQ879_001563"
     CDS             18453..19808
                     /gene="rlmD"
                     /locus_tag="VQ879_001563"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3143692.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         5985 a         3584 c         4378 g         5867 t
ORIGIN      
        1 tccttagata gcgcatggtt atagacttta tcttcaactg ttagtggctt gagtttgctg
       61 gatttacgtg gagtttgtgc ttgaggatat atcttcatga gcccttgata attactgtca
      121 gccaagattt taccagcttg tccgactttt ttgataagct gtttttaata cagctaacat
      181 ctctttaaaa gtggtacgct gaacactaac aagacgctta aatcgtgcat cagttagttg
      241 tttacttgct tcataattca tagaactact ataccatatt ttgtttcgca ggaagtctaa
      301 taagttatag tccagttttt actatacttt gatattcaaa tatgttatac tatggttatc
      361 aaagtaaatg aaaggagtta cgaatatgac gccagaagaa atgtacctga cagagcgatt
      421 agacgtacag atagctcatt ttttaaagaa aagcgttcaa catcgtaggc gctataaggt
      481 attaaaaata acagaaatcg tggcaggttt cctcatagct gtcttttgtg ctattcctat
      541 gccaggtgat cgctaccgtt tgatttcggt tgccttatcc agtctcggct tgctgtgtga
      601 ggggattatc aatttgtata atgcaaagga aaattggatt tcttaccaaa aaactgcgca
      661 actcctggag aaagaaaaat tcctctatca atgccaaacg gagaaatatg caggaaagac
      721 caaggctttt gccctatttg tcaagacatg cgaaggtctt atctcagagg agattaacca
      781 gtgggaaagt atccagtcaa aagaagtggc agctagtgca gatgctccag ttaaaaaaga
      841 gtaggaggta gaggaaatgt ctcaatccag ttacctgtcg cccttgctct ggttaaaaaa
      901 agaagccgat aaggaaaaga tgagcgcgac ccagtgccag atatttttct tttactatca
      961 aatgtttgag ctcttatttg ctagagaaag cgacatgaaa gacttatgtc tgggaacgaa
     1021 aggtttttat ttctcgcagt tagagaaaaa tttgctttct ggagtttccc gatttctaaa
     1081 aaacttggag gggaaagtaa ctctcaaggc taaccaagaa gtatcagctc gcaaagccct
     1141 ttttctagcc ttgacaacta gccaatcaga ttggcaggag ttagctcctg tttttgattt
     1201 ttatcagact atcgggaggc ttgaaaatcc ttctctcttg agttctcagg acagacaaca
     1261 tctgatgtgg atttaccagt cagctttgga gaaggattat attgtcaagg ttattggcga
     1321 caagcatttt gtattgaaga gacaagatgc tactaaattg acagcgcgcc aaactcaaac
     1381 tttggaaatt ctgagtcaat cagaagactt ggtcaatcct gtctatgtta cattaggaga
     1441 aaagggggtg ctcttgcttg attaagagag gagatgttgt agctctttat ttgccttttc
     1501 cgactattag tagcgatttg gctgtgaaga atcatatgta tatctgtatt gacaacagca
     1561 tgactaaaaa caaagagttg gttaaaaatc agaccttcaa accagctctc ttgaccagac
     1621 gtttggtcaa gaactttatg atagaagagc cggatctagc tcgtaatcct tttacaagac
     1681 caaccttgat tgacttagat aaggtattta tgttggataa tacggttatt ccgacttctt
     1741 atctagccag acggcgacgc aatgtctcag aagaattgta cgaggaaatt ttggatcact
     1801 tagtccaacc acggctgatt tcgctgaaca agtctgagtt tatgcaactc aatccaggaa
     1861 cttattagga ggtagaagat ggcaaataaa gcagtaaatg actttatact agctatgaat
     1921 tacgataaaa agaaactctt gacccatcag ggagaaagta ttgaaaatcg tttcatcaaa
     1981 gagggtaatc agctacccga tgagtttgtt gttatcgaaa gaaagaagcg gagcttgtcg
     2041 acaaatacaa gtgatatttc tgtaacagct accaacgaca gtcgcctcta tcctggagca
     2101 cttctcgtag tggatgagac cttgttagag aataatccca ctcttcttgc ggtcgatcgt
     2161 gctccgatga cttatagtat tgatttgcct ggtttggcaa gtagcgatag ctttctccaa
     2221 gtggaagacc ccagcaattc aagtgttcgc ggagcggtaa acgatttgtt ggctaagtgg
     2281 catcaagatt atggtcaggt caataatgtc ccagctagaa tgcagtatga aaaaatcacg
     2341 gctcacagca tggaacaact caaggtcaag tttggttctg actttgaaaa gacagggaat
     2401 tctcttgata ttgattttaa ctctgtccat tcaggcgaaa agcagattca gattgttaat
     2461 tttaagcaga tttattatac agtcagcgta gatgctgtta aaaatccagg agatgtgttt
     2521 caagatactg taacggtaga ggatttaaaa cagagaggaa tttctgcaga gcgtcctttg
     2581 gtctatattt cgagtgttgc ttatgggcgc caagtctatc tcaagttgga aaccacgagt
     2641 aagagtgatg aagtagaggc tgcttttgaa gctttgataa aaggagtcaa ggtagctcct
     2701 cagacagagt ggaagcagat tttggacaat acagaagtga aggcggttat tttagggggc
     2761 gacccaagtt cgggtgcccg agttgtaaca ggcaaggtgg atatggtaga ggacttgatt
     2821 caagaaggca gtcgctttac agcagatcat ccaggcttgc cgatttccta tacaacttct
     2881 tttttacgtg acaatgtagt tgcgaccttt caaaatagta cagactatgt tgagactaag
     2941 gttacagctt acagaaacgg agatttactg ctggatcata gtggtgccta tgttgcccaa
     3001 tattatatta cttgggatga attatcctat gatcatcaag gtaaggaagt cttgactcct
     3061 aaggcttggg acagaaatgg gcaggatttg acggctcact ttaccactag tattccttta
     3121 aaagggaatg ttcgtaatct ctctgtcaaa attagagagt gtaccgggct tgcctgggaa
     3181 tggtggcgta cggtttatga aaaaaccgat ttgccactag tgcgtaagcg gacgatttct
     3241 atttggggaa caactctcta tcctcaggta gaagataagg tagaaaatga ctagtagagg
     3301 agaatgcttg cgacaaaaag aggcgatgat ctctctgcgg atatctgaaa gtttatctct
     3361 tgcctagcga tttccattgg agtatgctcg tgatgttaaa atgaatctat caaacagaat
     3421 gtgtaaaaaa gtaaaaaggg tagccaattc cttgatatac aggggattga ttatccttta
     3481 cttgttttag atgattggaa attcaagaat gacacgtatc ggaaatattt tgctgtttat
     3541 atctaatacc catttatgga aaaaatgaaa ttaaatatga acaaatcaat tgctagcaat
     3601 ggtttagaag tgccagtgta ctagtctaat ttctccatct tgggaacacg taaattatac
     3661 tcttcgaaaa tctcttcaaa ccaggtcagc cctatccgca acctcaaaac agtgttttga
     3721 gcaacctgcg gctagctttc tagtttgctt tttgattttt attgagtatt agaggtttgc
     3781 ttagaaactc ttctattgat ttcttagaat acaatagcgc ctataagaac tgttggattt
     3841 caaagtattt acttgaacta tgatatgtct ggagtagact gtcaacaaaa ggtgcagtat
     3901 gattgttttt gtcgcttata tctacaaact tcaaacagta atttgagctg actttgtcaa
     3961 acttggctga aactttctat ttgcagataa tggtctagtt tgttttttga atgtggatga
     4021 gtgtctgttg ataaagatag aaaggtaaga ccatcttagc aggtaaagtg ctatcctagc
     4081 ttgatttgct aataaaatcc atttcctcta gtgaaaatca aaaaaacttg tgttataata
     4141 agaaagatta aaatgtgaaa aaaggagatt cctaatggga cgtaaatggg ccaatatcgt
     4201 agccaagaaa acggctaaag atggagctaa ctctaaagta tatgcaaaat ttggtgtaga
     4261 aatctatgta gcagctaaaa aaggtgatcc agatccagaa tcaaactcag ctttgaaatt
     4321 cgttatcgac cgtgctaaac aagcccaagt gccaaaacac attatcgata aagcgattga
     4381 taaagccaaa ggaaacacag acgaaacctt tacagaagga cgttacgaag gttttgggcc
     4441 aaatggctct atgctaattg tggatacttt gacttctaac gttaaccgta cagcagccaa
     4501 tgtccgtgca gcctttggta aaaacggcgg aaacatgggc gcttcaggtt ctgtttctta
     4561 cctttttgac aacaaaggtg ttattgtatt tggaggtgaa gatgcggacg cagtctttga
     4621 gcaattgctc gaagcggatg tggatgtgga tgacgtagaa gcacaagaag gtacaatcac
     4681 agtttacaca gcgccaactg accttcacaa ggctatcgtt gctctccgtg agtctggtat
     4741 tgaagaattc caagtgactg aattggaaat gattcctcag tcagaagtgg aattgtcagg
     4801 cgaagacctt gaaacctttg aaaaacttta cagcgttctt gaagacgacg aagacgtcca
     4861 aaagatttat acgaacgtag atgggtttta atttaaccta tagaacatga tcctaagtga
     4921 gaaaatcact tgggattttt ttaatcaaga aaatagttct catagaaatt taattattct
     4981 ccagagaact atttttattt agaaggggga gattatggat aaaccgatgt tagtctttaa
     5041 gcgttttggt catcaaattt acctgatggt gcaaaaggaa gccaaacgtt gcggcattga
     5101 atttatgggt gggccgcaag gtcaggttgt gcgttttttg gataatcgcg agaaaaacca
     5161 agacttggtc ttgattaaag atatcgagca ggaactcaat attaccaagt ctgttgctag
     5221 taatctggtt aagcgtatag tgcaaaatgg tttggtggaa ttggaggcga gtcctgttga
     5281 taagcgggct aagtttgttc gtctgacgga caaagcacgt tctcagatgc aacaggttaa
     5341 ggcttttttg aacgcataga caagcagttg atggaagaca ttgatgaaga tgaattactg
     5401 atttttgaga aagttctcgg tcaactacag gcaaatatca agggaatagg aggagagaat
     5461 aaagaaatta gccaaaagaa ttagtagaaa agaatggggg atgattttac tagccattct
     5521 ctttacttgc ttttcggtct atctagagtt ggaagtgccg acctatatct cgaaaattac
     5581 ggatttgcta ggtagtcaag gaactaattt agatgagttg tggcagccgg caagcatgat
     5641 gatgggaatg ccctttcttg ccttcttgtc cgtagttgca gttggatttt ttgcatcccg
     5701 agtggcggct tcttatacta gtaggctgag aagtgatatt tttaaccgag ttttggatta
     5761 ctcgcagaca gagattaaga aattttcaat tcctagcctc ttgatgcgta ctaccaatga
     5821 cattactcaa gttcaaatgt tgattactat ggacttgcaa gtggtaacgt gtggtccaat
     5881 tatggctatc tgggctattg ggaagatttt aggtcattca gaatactggc tctgggccgt
     5941 acttgtggca gtgattgtca acgtcctgat gacgaccgtt ttgatgacgc tagcctttcc
     6001 aaaacagtcc ttgattcagg ggctgacaga taaactgaac agtatcactc gtgagagttt
     6061 aacaggtatt cgtgtcgttc gtgcctacaa tgcagaggat tatcaaaatg aaaaatttgc
     6121 agcagtaaat gatgaattga cccgttaaaa tttgtttgtc aaccgtctta tggctatttt
     6181 gaatcctatc atgatgggga tttcaagtgg tttgagtgtg gcgatttact ggattggggc
     6241 ctatgtgatt aacgacgctg ctccgatagc gcgtctgcct ttctttagtg acatgattgt
     6301 tttcatgtct tatgccatgt aggttgtcat ggacttcctt ctcatgggag cactcttcat
     6361 cgttcttccc cgaactatgg tctctgctaa gcggattaat caagttttag atttgcattc
     6421 ttctatccaa aaccctgctc aagtgcagct gactgatgaa aacttcaaag gtcaggtcga
     6481 gtttaaggat gtgaccttcc gctatgcggc aaattcggag gcagttattg aacatgttag
     6541 ctttaaagca gaaactggtc aaacagtggc ctttattggg tcaataggtt ctggtaaatc
     6601 aactctggtc aatctgattc cacgtttcta cgacgtgtca gcaggagaaa ttctggtgga
     6661 cggtgtcaat gttcaagact atgacttctc tgcgacagct catgctggtc aaagggttgc
     6721 cattgttggg ccgactgggg ctggtaagac aaccattgtc aatcttttga tgaaattcta
     6781 tgagattgat aagggaagta ttcgcattga tggtgtggat accaaggcta tgacgcgttc
     6841 agaagtgcat gatgcctttt caatggtctt gcaggatacc tggctctttg aaggaactat
     6901 tcgagacaat ctcatctata atcaaatagg gattagtgat gaacgaatga tggaagctag
     6961 taaggctgtg ggaattcacc actttattat gaccttgcca gatggctatg ataccatctt
     7021 ggatgacacc gtgaccttgt ctgtaggaca aaaacaacta ttgactattg ctcgtgccct
     7081 tcttaaggat gcaccgcttt tgattttgga tgaggcgact tcttctgttg acacacggac
     7141 agaggaattg atccaaaaag ccatggaccg tttgatggaa ggacgcacat cctttgtcat
     7201 tgcccaccgc ttgtcaacca tccgaaatgc agacttgatc ttggtcatga aagatggaaa
     7261 tatcatcgag caaggcaact atgaggaact gatggtgtaa ggtggcttct acgctgactt
     7321 gtacaatagt caatttacag aagatgaagc agaagaataa atcaaaagaa ggcttgacgg
     7381 ccttcttttt cttatttata ctagtacaca tagaaagaga gaagtatgag tcagaaatta
     7441 tacaatatga aatttgctgc tgtctactta gccttgattg caaaagttga gcgaaagggt
     7501 ggaaaggcag agtcagttca ccaagtgacc agttggttga cagggtatga agtgagtgac
     7561 gttcttactt gtctggatag ggatgttact tacggagatt tttttcgaca agcaccatat
     7621 tatgtccctg aacgaattgc aattacaggg aagatttgcg gtgtccgtat tgaggaaatt
     7681 gatgatcctc tgatgcagga aatacgtcgc ttggacaagc tagtggattg gcttgccaag
     7741 gggaaaacat ctcaacaagt tctagaaaag tatgagaagc ataaatgaaa aattatcaag
     7801 aatggtatcg aaatatcaga tccagactaa ctagtcgtcc aattctttta ttcctattac
     7861 gcagtttcaa tcgtttgatg acagtcgcca tgcccctggt ctatctgatc ttgctagtca
     7921 ccacttacct gcaactagga cttggtcagc aagttggagt ttatgtgctt attcctgcat
     7981 caggttttgt ggccttgtcc ctgtttcgta aaaaaatcaa tcacccgaga ccttatgaaa
     8041 cttgggatat ctgtcccctt cttgataagg atagttcggg acggtcgatg cccagtcgcc
     8101 atgtcttttc tgcaactatc atctccatgg cctgtctgca tgctagtcta cctattggct
     8161 tagtatgctt gatcttttca gctttgctgg ggttggtgag ggttttaggg ggtgttcatt
     8221 atcccaagga tgtcttggtt ggctatgctt gtggtctggt gtggggattc cttttcttct
     8281 tattctgaca tgtaagttaa gctagtccta caaccactta ctgcttcaaa ttgaccactt
     8341 gcttttttgc ccttgtattc ctaacttagc tttgatatag tagagtcaga aaggagatgt
     8401 gatgaagtta cgaattgaga ttgacggcaa tttagaggag actgaaattg tcatcaagac
     8461 ccccactttg acagatgaaa ttgcagactt gcaacggctc ttgcaagaat ccaagtctcc
     8521 taggttgatt ttttacaagg ggacgggtga atattatctg gacttgtcgg aaattctctt
     8581 ctttgagaca gaaggtagca agatttatgc ccatacccag aaaaatgcct acgaagttcg
     8641 gctcaaactc tatgagttag aggctatcct tcctcgctat tttagtcgag tatccaagtc
     8701 aacgatcgtt aatattcggc aaatctattc ggtggacaag tccttttcag gaacgggcac
     8761 catttccttt tatcaaaccc acaaggaggt tcatgtgtca cggcattacc aatccctcct
     8821 aaaagaaaat ctaagaaata tgaggtaaga acatgaaaaa gaaagcattt ggtattgtgt
     8881 tgcttgtact agcagcttta atattagtac aaggaaattt tggaatccct tctctaggag
     8941 ggcacatttg gcccttgatt ggtattgctt tttttgccta ccaatcagtt ggagctttgt
     9001 tgcgtcgcca cttaacttca gcctctttta cagctctagt agccttaatg attgctaacc
     9061 acttttatgg cattttaccg attccaaacc agacactaat ctgggcagga gttctaatcg
     9121 ttctcggagt aaatatgttg actcattcta acagaacttg gaatgggaaa aaatggtggt
     9181 atgatggtga aaaaaacatt cttatagata aggaagttgc ttttgggaca gggactttct
     9241 acaagcaaga ccaagaattg gtagaagacc aagtagaagt tggttttggc aatgcaaaaa
     9301 tctactatga caatgcagag atgttaggtg attttgcaac tttaaatatt gaagtagctt
     9361 ttggtaatgc aactgtctat gttccgcaac actggcgtgt cgatttgaaa gtagaaacat
     9421 cctttggtgc agccaaggcg gacgctcctg tagccccaac cagcaaaacc ttgattatcc
     9481 gtggagatgt ggcttttggg aagttggaaa ttgtctacgc taaataaaaa aatcttcact
     9541 tcaaccatca aaataggcgt actaagagta ggaaattgat gccttgctct gatttcagtt
     9601 ctatggttgt tagactttaa aaaatgaaat gctgccttta aaagttgtat atttttcgat
     9661 attttggctt ttacgtttga tgtatctatg tactacagcg tagatgatgt agtgtcgaat
     9721 gcttttaaaa aacgaatgat attggacagt ttttttgcct ttaattgctc aggaaccatg
     9781 aaagtcagta cttgggttta tgacaaggga gaatggtatt atgtaagttc ttctggttcc
     9841 atgattgcga atgattgggt caaagacaat ggcaagtagt attatctggc ttcatcaggt
     9901 aagatgcttc gcaataccta cacacctgat ggttactacg ttggcaactt aggtgcctgg
     9961 caataagaat aatactcttt gaaaatctct tcaaaccacg tcaacgtcgc cttatctaca
    10021 acctcaaaac cgtgttttga gcagcctgcg gctagctttc tagtttgctc ttagtataag
    10081 aagtcctttt ccttaaagga agaggctttt tacttgcttt tctgctgctt cctcatttgt
    10141 cctgaagcct tttttgtgtt aaaatgaatg gtatgaaagc taaaaaaatg tggatggcag
    10201 gcttggctct gctaggtatc ggaagccttg ctcttgctac gaaaaaagtt gcagatgacc
    10261 gtaagctcat gaagactcag gaagagttga cagagattgt gcgagaccat ttttccgaca
    10321 tgggggaaat tgcgaccctt tatgttcaag tttacgaaag cagtctggag agcttggttg
    10381 gtggcgtcat ttttgaggat ggccgtcatt atacctttgt ctatgaaaat gaagacctag
    10441 tctatgagga ggaagtctta tgatacagcc agcaagttta gaagaattag catctttagt
    10501 ggaaaaagcg ggcaagaagg tcttcctttt tgtggcagac tggtgtggcg attgtcgtta
    10561 tatttatcct gccttaccag agattgaaga gaccaatcca gagttcacct ttattcgaat
    10621 ggaccgagat cagtatatgg atttggccaa actctgggat gtttacggaa ttcctagcct
    10681 tgttgttcta gaaaaggaca aggaaatcgg tcgttttgtc aatcgcgacc gtaaaagtaa
    10741 ggagcaaatt aacgattttt tagcaggatt gaaataggag aaaaaggaaa caatgatttt
    10801 tacgtataac aaagaacatg tcagtgatgt ccttatggtc atcgtgaaaa atagcggaga
    10861 tgccaaactg aatgtggaac gcaaaggcaa ggtagcccgt gttttcctca aagaaaatgg
    10921 ggaaacagta gcttggaaca tttttgaggt ttcgagcttg tttgaaattg cagagcgcgg
    10981 tcaagtcttt ttatcagatg agcaagtcgc tcgtttgaac caagaattac aggcggaagg
    11041 ttttacagaa gaaattgtta atgataagga acctaagttt gttgttggtg aaattgtcga
    11101 gatggtagct catccagaca gtgaccacct caacatctgc caagttgcag tcgcaagtga
    11161 caagatagtg caaatcgttg caggagcacc taatgcgcgt gttgggttga aaaccattgt
    11221 ggctcttcct ggtgccatga tgccaaaagg gaatttcatt ttcccaggcg aacttcgtgg
    11281 tgaaaagagt tttgggatga tgtgtagtcc tcgtgaattg catttgccaa atgctccgca
    11341 aaaacgtggg gtgcttgaat tatcagaaga ccaagttgtc ggaacaccgt tcgacccagc
    11401 gaaacactgg actgcctagg aacttgtcag catctgatag aaggaaataa gatggcaaaa
    11461 aatgtagtga ttacgggagc aacctcagga atcggtgaag cgattgcgcg tgcttatctg
    11521 gagcagggtg aggatgtcgt tctaacagga cgacggatag acagattaga aatcctcaag
    11581 tcggagtttg cagtaagctt tccaaatcaa accgtctgga cttttccact agatgtgacg
    11641 gatatggtca tggtgaagac tgtttgctct gatattctag aaacgatagg gaggattgat
    11701 atcttggtca acaacgccgg actggctctt gacttggctc cctatcaaga ctatgaggag
    11761 ttggatatgt tgaccatgtt ggataccaat gttaaaggtc tgatggcggt tactcgctgt
    11821 ttcttgccag caatgataaa agtcaatcaa ggtcatatta tcaatatggg gtcaaccgca
    11881 ggaatctacg cctatgctgg tgccgctgtt tactcagcta ccaaggctgc ggttaagacc
    11941 ttttcggatg gactgcgaat tgataccatc gcaacggata tcaaggtgac aaccattcag
    12001 cctgggattg tcgaaacaga tttctcaact gttcgttttc atggtgataa agagcgagct
    12061 gcgtccgttt accaaggaat agaagccttg caagctcagg atattgcaga cacagtagtc
    12121 tatgtgacca gtcagcctcg ccgtgttcag attacagata tgaccattat ggccaatcaa
    12181 caggcgacag gtttcatgat tcataaaaaa taagaaattt cctcgaaaag ttacaaattt
    12241 ctgtaacttt ttttgatttc ctacgaatag ataagtagga ggaagaaaat atgtataata
    12301 aagttatcat gattgggcgt ttaacgtcta caccagaatt gcacaaaacc aacaatgaca
    12361 agtcggtagc gcgagcaact atcgctgtga accgtcgtta caaagaccaa aacggtgaac
    12421 gtgaagctga ttttgtcaat atggtcctat ggggcagact agcagaaact ttggcaagct
    12481 acgcaaccaa aggtagtctc atttccgttg atggagaatt gcgtacccgt cgctttgaga
    12541 aaaatggcca aatgaactac gtgaccgaag tacttgtaac aggattccaa ctcttggaaa
    12601 gtcgtgctca acgtgccatg cgtgaaaata atgcaggcca agatttggca gatttagtct
    12661 tggaagagga agaattgcca ttttaatact cttcgaaaat ctcttcaaac cacgttagct
    12721 ttatccacaa catcaaagca atgctttgag cagcctgcgg ctagcttcct agtttgctct
    12781 ttgattttca ttgagtataa acattaaaaa gtctgagttg gtctcaggct ttttatcttg
    12841 agaaagtcag acttttttct tgattatttc tgactaagtg atacaataga actatgaatt
    12901 agcactcagg tataaagagt gctaataata tctatctcat tatggaggaa atcagatgtt
    12961 gaaaccatta ggggaccgtg tggtcttaaa aatagaagaa aaagaacaaa ccgttggggg
    13021 ctttgttctc gcaggttcag cccaagaaaa aaccaaaaca gcccaagttg tggctactgg
    13081 acaaggtgtt cgtaccttga acggtgactt ggttgctcca agtgttaaaa ctggagaccg
    13141 tgtcttagtt gaagcccacg caggtcttga tgtcaaagat ggcgatgaaa agtacatcat
    13201 cgtaggcgaa gctaacatct tggcaatcat tgaagaatag aaggagaaag taagtatgtc
    13261 aaaagaaatt aaattttcat cagatgcccg ttcagctatg gtccgtggtg tcgatatcct
    13321 tgcagacact gttaaagtaa ccttgggacc aaaaggtcgc aatgtcgttc ttgaaaaatc
    13381 atttggctca ccattgatta ccaatgacgg tgtgactatt gccaaagaaa tcgaattgga
    13441 agaccatttt gaaaatatgg gtgctaagtt agtatcagaa gtagcttcta aaaccaatga
    13501 tatcgcaggt gacggaacta cgactgcaac agtcttgacc caagctatcg tccgtgaagg
    13561 aatcaaaaac gtcacagcag gtgcaaatcc aatcggtatt cgtcgtggga ttgaaacagc
    13621 agttgccgca gcagttgaag ctttgaaaaa caacgccatc cctgttgcca ataaagaagc
    13681 tatcgctcaa gttgcagccg tatcttctcg ttctgaaaaa gttggtgagt acatctctga
    13741 agcaatggaa aaagttggca aagacggtgt catcaccatc gaagagtcac gtggtatgga
    13801 aacagagctt gaagtcgtag aaggaatgca gtttgaccgt ggttaccttt cacagtacat
    13861 ggtgacagat agcgaaaaaa tggtggctga ccttgaaaat ccgtacattt tgattacaga
    13921 caagaaaatt tccaatatcc aagaaatctt gccacttttg gaaagcattc tccaaagcaa
    13981 tcgtccactc ttgattattg cggatgatgt ggatggtgag gctcttccaa ctcttgtttt
    14041 gaacaagatt cgtggaacct tcaacgtagt agcagtcaag gcacctggtt ttggtgaccg
    14101 tcgcaaagcc atgcttgaag atatcgccat cttaacaggc ggaacagtta tcacagaaga
    14161 ccttggtctt gagttgaaag atgcgacaat tgaagctctt ggtcaagcag cgagagtgac
    14221 cgtggacaaa gatagcacgg ttattgtaga aggtgcagga aatcctgaag cgatttctca
    14281 ccgtgttgcg gttatcaagt ctcaaatcga aactacaact tctgaatttg accgtgaaaa
    14341 attgcaagaa cgcttggcca aattgtcagg tggtgtagcg gttattaagg tcggagccgc
    14401 aactgaaact gagttgaaag aaatgaaact ccgcattgaa gatgccctca acgctactcg
    14461 tgcagctgtt gaagaaggta ttgttgcagg tggtggaaca gctcttgcca atgtgattcc
    14521 agctgttgct accttggaat tgacaggaga tgaagtaaca ggacgtaata ttgttctccg
    14581 tgctttggaa gaacctgttc gtcaaattgc tcacaatgca ggatttgaag gatctatcgt
    14641 tatcgatcgt ttgaaaaatg ctgagcttgg tataggattc aacgcagcaa ctggcgagtg
    14701 ggttaacatg attgatcaag gtatcattga tccagttaaa gtgagtcgtt cagccctaca
    14761 aaatgcagca tctgtagcca gcttgatttt gacaacagaa gcagtcgtag ccaataaacc
    14821 agaaccagta gccccagctc cagcaatgga tccaagcatg atgggcggga tgatgtaagc
    14881 attctataga aaacaactta taaaaaacac aaaaggaggg aatgactaac ccttcttttt
    14941 ataatattca cttctaaatt gatttgagct ctcctaactt atatgataaa ataagactag
    15001 aaaaaggaga agaacatgat cgatgtagaa aaaattctgt gcaagatgcc ccccaatcag
    15061 aagattaatt atgaccgtgt catgcagaaa atggtagaag tatggtagaa aaatgagcaa
    15121 cggccaacca ttctcgtgca tgtttgctgt gccccttgta gtacctatac actagaatat
    15181 ttgaccaagt atgcagatgt gaccatctat tttgccaatt ctaatatcca tcccaaggta
    15241 gaataccata agcgggtcta tgtcaccaag aaatttgtta gtgattttaa tgagcggaca
    15301 ggaaatacgg ttcagtacct agaagctccc tacgaaccca attaataccg aaaactagtt
    15361 aggggactag aggaggagcc cgaaggtggc gaccgttgca aggtttgttt tgactaccga
    15421 ctggataaaa cagcgcaagt ggctatggac ttgggctttg actactttgg ttcagccttg
    15481 accatcagtc ctcataagaa ttctcaaacc atcaacagca tcggaatcga tgtgcaaaaa
    15541 atttacacga cccactatct tcccaacgat ttcaagaaaa atcaaggcta caaacgttca
    15601 gtagagatgt gtgaggagta tgatatctat cgtcaatgtt attgtggctg cgtctatgca
    15661 gcccaagccc agaatattga cctggttcaa gttaagaagg acgctacagc attcttgttg
    15721 ggtaaggatg ttgagaaaga ctattctcat atcaaattta tagtagattg aaactagaat
    15781 agtacacctt tacttctaaa acattgttag aaatcgattt gactgtcctt atttcatttt
    15841 actatactat tacgaaatta gatatataaa tgaaaacttg cctcaaggta ggtttttttg
    15901 ctagtagaaa agcgatagac agaaattgtt ggactcttaa aaaaatgaag ttttgctcaa
    15961 aagagcttct taaattaaaa cgagcaatta tcagttcaaa tctgtttcaa aagaagaacg
    16021 gataaattaa tcgatgcttt gtttttgagt taggaagtta agcatgccaa actgagtcgt
    16081 aggaataaat ctctttctag taatgtgttg taactctgct ataatggatt tattcctttt
    16141 tgtgtttaca caatttattt tatactacca aaaaaacaag gtcaggattt tgttcctgac
    16201 ctttgacaac tttaccgatt ctttagttct acatagcgct tgtaccaaat gtttacatag
    16261 gcttctgaga aaggaccacg tccattgtta atccaatcaa caagaatttt gacatgttct
    16321 tttaaaatat agtccaagtc atcagaataa ttcattttgc gtttgtgacg ctcgtactct
    16381 tcaacgtcca agagacgttt ttccccatct gtaaaaattt taacatccaa atcgtaatca
    16441 atatacttca gtgcttcttc atccagatag taggggctag ccatattgca atagtaagaa
    16501 gttccattat cacgaatcat ggcaatgata ttaaaccaat atttcttgtg aaagtaaaca
    16561 atagccggtt ctcgagtgac ccaacgacga ccatcacttt cggtaacaag tgtatgatcg
    16621 ttgacaccaa taatggcgtt ttctgttgtt tttagtacca tggtgtcccg ccaagttcgg
    16681 tggagactcc catcatgctt ataactttga attgtaataa agtcgccttc ttttggaagc
    16741 ttcataacta accaactttc tacaatttat aagtttatca tttactattg taccataaaa
    16801 ttacctaaaa tctgtgaatt tcacttggaa atattaaaga tattctctaa gagcgcttgc
    16861 tatatccgaa aaatcgtagc cctttcgtgc taaaacttga gttaaacgct gcttcagttc
    16921 gtatccttca tactttcgag catacttact atattgttta tcaagttcct tgaagatgag
    16981 ttcttgagtc gtttcttggt caacttggct atctaagtcg tcaaaggcaa ttttagcatc
    17041 agaataagag aagcccttgt tagtcaagtt ctggataatc ttatcttgca gggcacgaga
    17101 tggaagtttt ccctcatatt ttttcaatag tttattagct acacgttgag caacttcaga
    17161 aaaatcaaat tctttcaagt tctcttctat agtagatttt gaaatccctt tttgagctag
    17221 tttctgagtc agcacataag gacccttgtc tcctgaaagt tgattggtat tgatgatagc
    17281 ataagcgtac tgaccatcat taatccactt atcttcttta agattagcaa taacttgaga
    17341 aacgatgttt ttatcaatat cgtatttttt cagatattct ctgacttctt tttcagtgcg
    17401 tgctttaaag gataagtggt agagagcgag attcttacca taagaaaact gggcaaaatc
    17461 ctgaatctcg gtcagttcct ctttactaat gaccttatct cgagacagca taaaacggac
    17521 aatggtatct tccgtgatat aagaggtttg ctgtccatct agttccatca agtagagacg
    17581 ttttttcttt tcaagttttg tgattttcat aatttccttt catctaaatg cttcgaaagc
    17641 tgcaacaagt cgtagtttat ccatatttac atattctcta ccgtaatagt cgagaaataa
    17701 ttcagcatac gtagcatctt gtaggttgta atgaagggac caaattgccc aaaagaggtc
    17761 gatatgtcgg tcactaaaac cagccaatcc caagtcaata aagcaagaaa aatgagaggc
    17821 atccttcaag atgaaatttg gcaggcaggc atctccatga ataaaagcat cagctttgag
    17881 aatgtaacct ttctcttgta tcagttggta agcttcttca cgactgtgaa tgtgaaattg
    17941 aggcagaaga gtcttgttat aaaaagtccc cttctgatag ttttttaagg ctttttcttt
    18001 ataacgcttc agatgatttt ccgacggaaa agattgtggt ttaagactgt gaagtttgtt
    18061 taatgcttga gccagggttt gacagagtct ttcgggttga tttaaaaaag cgagagcgtt
    18121 gctgccaatg gcttctttag tcagaaggaa gtccttattt gctgataaat aggtaatcac
    18181 tggagttccc aatccttcag tttcgaacca acttgcaatc ttagtttctt gagctaatct
    18241 gcctttttga tctattttta aatagtaacc tgaatctata tataggacag ttgcacttga
    18301 atgagaagaa ctatcagaga gattagctcc cttgatatag cttcgtaatt gttcagggaa
    18361 atctagtata ctaaagcgag gtgtttttga attcatgctt ttattgtaac atattcttaa
    18421 atatcttaga aactccatgg tataatagac atatgaatct gaaagtgaaa caaaaaatac
    18481 cattaaaaat caagcgcatg ggaattaacg gtgagggaat cggcttttac caaaaaacat
    18541 tagtctttgt accaggagct ctcaaaggcg aagatatcta ttgtcagatt acttctatta
    18601 gacgcaactt tgttgaagca aaattactga aggtcaacaa gaagtctaaa tttcgaattg
    18661 tgccatcttg tactatttat aatgaatgcg gaggctgcca aatcatgcac ctgcattatg
    18721 ataagcagct ggagttcaag acggacttac ttcatcaagc gctgaaaaaa tttgctcctg
    18781 caggatatga aaattatgaa attcgtccaa ctattggaat gcaggaacca aaatattaca
    18841 gagctaagtt acaatttcag actcgaaaat ttaaaaatca ggtcaaggcg ggcttatatg
    18901 cacaaaactc tcactattta gtagagttga aagactgcct ggtacaagat aaggaaaccc
    18961 aagtgattgc taatcgctta gcagaattac ttacttatca ccagattcca atcacggatg
    19021 agagaaaagt tctaggtgtc cgtactatta tggtccgacg cgcgagaaag accggacagg
    19081 ttcagattat tattgttaca aaccgccagc ttaatttaac tcaattggta aaagagttgg
    19141 ttaaagattt cccagaagtt gtgacagtag ctgttaatac aaatacagct aaaaccagtg
    19201 agatatatgg tgaaaagaca gagattatct gggggcaaga gagtattcaa gaaggtgtac
    19261 tcaattatga attttcacta tcccctcgag ctttttatca actaaatcct gagcaaacag
    19321 aagtcctcta tagcgaagca gtaaaagcgc tggatgttga taaagaaaac catttgattg
    19381 acgcttattg tggagttgga acgattggat ttgcctttgc aaagaaagta aaaacactca
    19441 gaggtatgga tattattcca gaagctattg aagatgccaa gcgaaatgct aaaagaatgg
    19501 gatttgacaa tactcattat gaagctggaa cggcagaaga gattattcct cgttggtaca
    19561 aggaaggcta ccgagcagat gctttgattg ttgacccacc acgtacaggt ctggatgata
    19621 agttattaga tactattctt acttatgtac cagaaaaaat ggtttatatt tcttgtaatg
    19681 tttcgacctt ggctcgtgat ttggtacgct tagtagaagt ctatgatctt cattatatcc
    19741 agtcggtcga tatgttccca catacagctc gaactgaagc tgttgtaaaa ttaataaaaa
    19801 aagtttaaaa aagg
//
LOCUS       DAVBOU010000040        19351 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBOU010000040 DAVBOU010000000
VERSION     DAVBOU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.040"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(123..674)
                     /locus_tag="VQ879_001564"
     CDS             complement(123..674)
                     /locus_tag="VQ879_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143693.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1024..1848)
                     /gene="nadE"
                     /locus_tag="VQ879_001565"
     CDS             complement(1024..1848)
                     /gene="nadE"
                     /locus_tag="VQ879_001565"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3143694.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(1845..3305)
                     /locus_tag="VQ879_001566"
     CDS             complement(1845..3305)
                     /locus_tag="VQ879_001566"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3143695.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3421..3909)
                     /locus_tag="VQ879_001567"
     CDS             complement(3421..3909)
                     /locus_tag="VQ879_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143696.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(3899..4108)
                     /locus_tag="VQ879_001568"
     CDS             complement(3899..4108)
                     /locus_tag="VQ879_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143697.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(4494..4974)
                     /locus_tag="VQ879_001569"
                     /pseudo
     CDS             complement(4494..4974)
                     /locus_tag="VQ879_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5134..5868)
                     /locus_tag="VQ879_001570"
     CDS             complement(5134..5868)
                     /locus_tag="VQ879_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143698.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(6203..6673)
                     /locus_tag="VQ879_001571"
     CDS             complement(6203..6673)
                     /locus_tag="VQ879_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3143699.1"
                     /translation="MDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQ
                     LFGARRKIPEYKFVAEVISYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDL
                     HEAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTVRA"
     gene            complement(6694..6933)
                     /locus_tag="VQ879_001572"
     CDS             complement(6694..6933)
                     /locus_tag="VQ879_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3143700.1"
                     /translation="MRDANRGGCSQSCRWKYDLYDMPFGKERKSLQGEIPEEFSMSAV
                     DMSMIDHIPDMIENGVDNLKIEGRMEWSLFTTYQQ"
     gene            7104..7253
                     /locus_tag="VQ879_001573"
     CDS             7104..7253
                     /locus_tag="VQ879_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143701.1"
                     /translation="MRFIVGRFTSFSLEIEFSPTSKLDDLLFKIAFLMILATWIKARK
                     TKGAT"
     gene            complement(7182..7493)
                     /locus_tag="VQ879_001574"
     CDS             complement(7182..7493)
                     /locus_tag="VQ879_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143702.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(7508..8794)
                     /locus_tag="VQ879_001575"
     CDS             complement(7508..8794)
                     /locus_tag="VQ879_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3143703.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            9417..9599
                     /locus_tag="VQ879_001576"
     CDS             9417..9599
                     /locus_tag="VQ879_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3143704.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            9609..9959
                     /locus_tag="VQ879_001577"
     CDS             9609..9959
                     /locus_tag="VQ879_001577"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3143705.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            9967..11157
                     /locus_tag="VQ879_001578"
     CDS             9967..11157
                     /locus_tag="VQ879_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3143706.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(11672..12664)
                     /locus_tag="VQ879_001579"
     CDS             complement(11672..12664)
                     /locus_tag="VQ879_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143707.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            12824..14578
                     /locus_tag="VQ879_001580"
     CDS             12824..14578
                     /locus_tag="VQ879_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143708.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            14562..16283
                     /locus_tag="VQ879_001581"
     CDS             14562..16283
                     /locus_tag="VQ879_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143709.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            16294..16878
                     /locus_tag="VQ879_001582"
     CDS             16294..16878
                     /locus_tag="VQ879_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3143710.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            16878..17573
                     /locus_tag="VQ879_001583"
     CDS             16878..17573
                     /locus_tag="VQ879_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3143711.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            17561..18925
                     /locus_tag="VQ879_001584"
     CDS             17561..18925
                     /locus_tag="VQ879_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143712.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         6566 a         3305 c         3283 g         6197 t
ORIGIN      
        1 aggaactaga acatctgtct tgtactaatc aatatgctat tttaaagttt caaataaact
       61 tggaatgcta attattatat ttacaataaa tagttgactt cgatagaaac agaaaataga
      121 attcaacatt cttccctact tataccataa taaataagat ccgcaagata gccttttctc
      181 tctacaccat taacaatggt ttgtagatag gacattccag ccttttccat gacacgacct
      241 gaagctgggt tgagactggc ataacgtgct ctgacctttt gaaaacctgc ttgagtaaaa
      301 caaaagtcca agatagcttt caaagtctct gtcatcatac catttcccca gtaagccttg
      361 cctaacacat agccaatttc acagcttaaa tcagcctcgt ctatcttaac aatgctgata
      421 tctcctatta cttgctctgg gttttctttt agacaaatgg cccatttata atagttgaga
      481 ttagtatagg aagcaaccca attgcaaatc gagtttcgag tgatttcgac atcaggatgg
      541 ggatcccagg taacataggt cagattctca gcggatgaag cccaattttg aaacatggct
      601 tctgcatcac tctccacaaa tcttcttaaa atcaaacgtt ctgtctgtaa tatttgcgta
      661 ccgatagatt tcatgatgct acctcacttc cttatttcta tactcgtagt aaaaaggctc
      721 aactcagtaa cagctagaaa acgagtttgt cttctaattt cttgacgcag ttgctgcctg
      781 gtttgaaatg cgctctagca agctttttca aacctagtca tcgttgcagg ggtaagacga
      841 tgaaatcgaa ctcttcgagt tactgaatct gcctcatttt cttatttcta aactcggggt
      901 tcaagatccc ccagaccttc tctcactttc ttatttcaag atgagaggct gaaaacctcc
      961 agtggaggtt tttcttgctt tttaatttca gggcaagaag ctaaaaaggt cccccggacc
     1021 tttttactcc caaaagtcat caaatacggt gatgggtaag tggcgtttgt gttggccttt
     1081 gtgccaccag ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta
     1141 gtcgtcaatc tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc
     1201 ttcttctagg tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg
     1261 caagagctgt tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc
     1321 gtcaccaaac ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac
     1381 cgctccgcta tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat
     1441 attccccttg ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc
     1501 atcagctgat tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc
     1561 tttttgagca tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt
     1621 gtagctatcg tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgtcc
     1681 tgccaaggtt gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg
     1741 ttttttcaga tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat
     1801 cactggtttg acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct
     1861 tcaccaaggg cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca
     1921 cgcgccaaat ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac
     1981 ttgtcaaatt ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact
     2041 aatattcctt ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc
     2101 ttcttgatgt atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc
     2161 acaccatcat aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc
     2221 cacacctgct tcttacctgg cgtagaaact ttttcagcat tattagacag cttaatcgta
     2281 ttgcgcatct gaccagtttc atcttcgatt gcaacaatct tgtaaaccgc cccaagagcc
     2341 ggctggtcat aggctgtaat cagcttggta cccacacccc agacatcaat cttggccttt
     2401 tgcatcttga ggttaaggat ggtattttca tctagatcat tagaagcata aatcttagcc
     2461 tctgtaaatc cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc
     2521 ccagagtcaa tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga
     2581 atggcagctg gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt
     2641 ttgtgggtcg cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag
     2701 gcatgggcat gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgcta
     2761 gttccattgg cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct
     2821 tgagcccgac gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga
     2881 gctgccttcg tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc
     2941 aactgacatt gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa
     3001 tccccttctt gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag
     3061 aacgccccat gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag
     3121 tcttcaagat agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa
     3181 ggctgttggc ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag
     3241 taaacctgca tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga
     3301 tacatacttt tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt
     3361 attccaataa attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag
     3421 ctattctcca ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc
     3481 atagctctta agaccaagat tgccaataaa gatccacgga aggtaaatga tataagtaat
     3541 gacccaagca gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa
     3601 ttgataattc tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa
     3661 aatcgtaaaa tgaaaacgac tatagtaggt cactcccaga taacgggcac gattgaaaaa
     3721 gtaaaatgtc cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc
     3781 taatactgaa atgatataag ataggagcga caaagcgatg cagatataga aactttcaga
     3841 gcccgcttta ttgaacagtt gttcttctct ttcgtctagt aattgataat aataaaatct
     3901 atttttcatc ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa
     3961 tggactggca gagcgagaga ctgggattgt atttccccgc ttctatcaaa ccaatagtct
     4021 ggcgcgtcac cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag
     4081 ctaattttaa ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct
     4141 actcttaaaa aatccaaaac caacacaagc tatcagctat ttattataac cccattaatt
     4201 tgcactccag tattatcttc agccgaaaat cagtatttta ggttgtttga aataaacttc
     4261 ctagtttact cttttatttt tatttagtat tagctttagt aggatctttt aaacgagttt
     4321 ttattgctta tatttcttgt ttagtttagt tggtttcata tcactattat ataatgcttt
     4381 tggaaatgag cctagtataa gtcaaaaacg tgttgaatag tgaaagcagg agcataccaa
     4441 gatgactgat ttttttattg tattttaggt atgcaaaata atactaaatg aaactaaaat
     4501 gaatacttct tgcttttctt gagagtgaaa aagtacaata aaatgattgt agtgattagc
     4561 acaagatact gactaataga catcgtattt gaagccacaa atacaggtaa agaataaaaa
     4621 aggaagaagt tcaattgctt tgataaacaa atcattacta gtattcatca tcatcgtatt
     4681 taatatatta gagataaaga gtagtaaagc tactaaaata ccaaatacca agccactttt
     4741 caatttgtat aaatagaaaa tgtaagataa tagaaaataa aacaggacta acaaaattgt
     4801 attgactaca atagctacta taaaatttaa tcctaaatca cctggaatac ccaatttact
     4861 tactatgact agtaacacaa tgccattcaa agcataaata atggaaactg agatagcata
     4921 tagaaaatta gacaagacgt aaatcatccg attcttctgt ttatttaatt tcatgattat
     4981 aaccttcctt tattttgaac gatttaggta aatatcttta agcgtctctt ttttagtttc
     5041 aaaatcaact actttaatag agttttcgtt aaaaaattta aaaagctcac tattttgaat
     5101 attcccagac atagtaattc tcaatccctc ttcctaaaca atatcccaaa attcttgttt
     5161 ggtaatgaaa atgtctctat ctgtagctga tgaaaaagct atctcaaaca agaaattatg
     5221 actatctttt cctacttttt gaaatgtcaa aagcccgttc tccaagaaaa gaactctctc
     5281 acaaatttct tcaatgtctt ctaatttatg actcgatatt aaaattccca cattttcatg
     5341 taaagctaat ttttttagaa ccgctaaaac tatttgtgat gattcaatat ctaaaccatt
     5401 agtcggttca tctaaaatca atatatcagg ttccgtaacg agagttagaa gcaaagctaa
     5461 tttttgtttt gtacccaaag aataggtctt tactttttta ttaatagact gagtcaaatc
     5521 taactcttgg atcaaacatc taaatctttc ttgattgtag tcaacaccat ataaatttga
     5581 caaatatttt aaattctcta aacctgtttt agataaaaat aattttggtt cttcgattaa
     5641 atacccaaca ttatcactgc ttataatatt acctgaagtc ggttgattat tctgaacaag
     5701 aattttcatc aacgtactct taccaactcc atttctccct gctagaccaa caatttcacc
     5761 cttgttaagt gcaaaattta tatctttgag aatgattgaa tgaccataat gcttacttac
     5821 attttttatt cctccattaa tattattggt tttctctttg attctcatta attttaaaaa
     5881 gttgcgcctc tttttaacaa tattatatca tatatctaac ttaatgcaat atataaatgt
     5941 cattttgtga aattttatta acaaaaaact ctctacaaca aaataataga gagttttctg
     6001 cttattaatt tttttcaaaa tatctaagac atcacttctt tgtttaattt gataggcttt
     6061 gatacctgag ctccgacttt atcacttaaa aaataaaaaa gacagctaat ctcttgcgca
     6121 tcaagggatt tcgccattct ttaatctcgt ttaagtgttg tatatggagc tttgcataat
     6181 tttttaaaac taaacaacta cattaagcac gaactgtgac gctggttcca tcttccttat
     6241 aaagattgat aagcccctct ttaagagctc gaaccatgtc tccagcttga acaggttgtg
     6301 ggactttaat agtcaatagt tccattggat ttggagcgcg gtcgatttta ttgcctttgg
     6361 cctcatgcaa atcttcaata taggtttcaa aatgacggaa acctggacca taaaactcaa
     6421 cttggtcccc ttcgttaatg acgttccgtt gacgaatggt tgctgtttgt gtcgcatcat
     6481 cataagaaat cacttcagcg acaaacttgt actcaggaat tttacgacga gcaccaaaca
     6541 actgctcatt ttcagatggt ataccatagt aaaatcctgt agccagttca cgttgggcaa
     6601 ccttccacat ctcgtccacc aagtcttgtt tgatagcttc aaacttttca ggactttcaa
     6661 gataggcatc cacagccgcc ttgtagcagt tggttactgt tgatacgtag tgaatagact
     6721 ccactccata cgtccttcga tttttagatt gtccacacca ttttcaatca tatctggaat
     6781 gtggtcaatc atagacatgt caacggctga cattgaaaat tcttctggaa tctcaccctg
     6841 caaactctta cgttctttcc caaatggcat atcgtaaagg tcgtatttcc aacggcatga
     6901 ctgagaacat ccaccacggt tggcatcacg catactctag acggattgtt ttgacaattc
     6961 taatctttta gactttgcat aataactgtt aaacagtcga aaattacccc agttttaaca
     7021 agtagtcaaa ataccagata aaggaaaaaa gtctttaaaa tcttaaaaac gcatagtatc
     7081 aggtattgaa caatcttgat attatgcgtt ttattgtggg aagatttact tcattttctc
     7141 ttgaaattga gttttctcct acttcaaaac tagatgattt gctatttaaa atagcgttcc
     7201 ttatgatttt ggcaacctgg attaaagcga gaaaaacaaa aggggcaact taaactttct
     7261 ttatattgct tatatgttag tagttttaga caaacaccac ataaaatagg cttatcctgt
     7321 atcaaagata agggatacgg ctcaaaaggg tgattttcta atgaatcatg acaccgataa
     7381 caagcataat actttttaca atcatagcat tgtaaagcaa taatatccag cttgctatgg
     7441 taatgaatgc atcttgtttg cttatccact aagaaaccct gtgcctctat catttccttt
     7501 tcctttctta agctcgaact gtgacgctgg ttccatcttc cttataaaaa ttgatgagtc
     7561 cttcttttaa tgcacgaacc atgtctccag cttgaacggg ttgtgggact ttaatagtca
     7621 atagttccat tggatttgga gcgcggtcga ttttattgcc tttggcatca tgcaaatctt
     7681 caatataggt ttcaaaatga cggaaacctg gaccataaaa ctcaacttgg tccccttcgt
     7741 taatgacgtt tcgttgacga atggttgctg tttgtgtcgc atcatcataa gaaaccactt
     7801 cagcgacaaa cttgtactca gggattttac ggcgagcacc aaacaactgc tcattttcag
     7861 atggtatacc gtagtagaaa cctgttgcca attcacgttg ggcaaccttc cacatctcgt
     7921 ccactaagtc ttgtttgata gcttcaaact tttcaggact ttcaagatag gcatccacag
     7981 ccgccttgta gcagttggtt actgttgata cgtagtgaat agacttcata cgtccttcga
     8041 tttttagact gtccacacca ttttcaatca tatctggaat gtggtcaatc atagacatgt
     8101 caacggctga cattgaaaat tcttctggaa tctcaccctg caaactctta cgttctttcc
     8161 caaatggcat atcgtaaagg tcgtatttcc aacggcatga ctgagaacat ccaccacggt
     8221 tggcatcacg catactcatg tggtttgaaa gagtacaacg tccagagtat gaaatacaca
     8281 tagctccatg gacaaaggct tcaatttcaa catctgtacg tttgcggatc tcagctaatt
     8341 cttccattga aacctcacgc gctaaaacga cacgagtcaa gcctagctct ttccagaact
     8401 caagggtttc atagttagtg gcactggctt gggtagaaag gtggatttca aggcctggtg
     8461 cttcagtcgc tgcaatcata atcaaggctg ggtcagatac gataactgct gcaatcccga
     8521 tatcacgcag tttacggaac cactcaccag caccagcttc atttccttcg tgcataacca
     8581 tattagccgc tacatagacc ttggcaccat acttggccgc aaactgcacg ccttcttcca
     8641 tctgttcgaa agtaaagttt cccgcacggc tacgaagacc ataggcctga ccaccgataa
     8701 agacagcatc tgctccatac tgaacagcta cctttagctt ctctaaagtc cctgcaggtg
     8761 ataaaacctc aggacgtttt aatgtttttg tcatgatttc tcctatttgc aatataaaag
     8821 tttgacattt ttccttctca ttttatagta aataaaggat aaaatcaagc ctagacggat
     8881 tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag tcgaaaatta
     8941 tcccagtttt aacaagtagt caaaaagtct agaaaagtaa aaaccagtat ccaaagatac
     9001 tgactcgtaa aaatacataa attagtcctt agatgactac tcccactctg ttgctcctat
     9061 aatggaaaag gattgataca gtctagaata tcgctttttt atttattatt ctgatataaa
     9121 actgttagaa ttgatttttt gttttatacc caaatatgaa tagagacgta gctaataagt
     9181 tgaataacat atttggaaaa atgagaaata gcaatattac tagaactttt agaaacaatc
     9241 aatatttaaa aagaaaaagc tcaaagaatt tattaaacca tgttataata gatatagcta
     9301 taattttatt tataacaaga ggatagaaat gaccgaatta gaaagaaaaa atcgaaaaat
     9361 tagctaagaa atattctgat aacttaaaca tcaaagttca agagagagtt cgtgaaatgg
     9421 caaatgataa taagagccat tatttgatat acagagtttt aggtatttca tttgaagaag
     9481 gagaaaatat cgatttgtat caaaataaag gtcgtttttt atacaaatat gctggttcat
     9541 ttttagaaga agctgcagta ctatccttta acgaaaaatt tggtacagaa aatacttaaa
     9601 aagttaacat tcctaattct gaaagtacaa aacctaagac ttttgaaatt gattgtttag
     9661 tcggagaaaa acacgcatac gaaataaaat ggtgggatgc aactacagat ggagaccata
     9721 taactaaaga acacactaga ataaaagtta ttcataacaa aggatatata ccaattcggt
     9781 taatgttcta ctatccaaat agaactcaag ctataaaaat tcagcaaact ttagaaacat
     9841 tgtataacgg tattggaggg aaatattatg gagattctgc ctgggaagat ttaagagcag
     9901 tgaccggtat tgatttactt agtattctaa cagatattgc aaataaaaaa caggggtaaa
     9961 atcaaaatga cagtattaaa aggagataac ttagaaatat taaaaactat tgaatcctca
    10021 agtattgatt taatctatat ggaccctcct ttctttacac agaaaaccca aaaattatct
    10081 aataacaaaa atattatgta ttcattcgaa gatacgtgga cttcgattga ggattacaaa
    10141 gaatttttgt ctgtaagatt agaagaatgc aaaagagtgc taaaaaatag tggcagtatt
    10201 ttcgttcatt gtgataaaat tgcaaatcat catattagat taattttaga taatatcttt
    10261 ggagcagata tgtttcaaag cgaaattata tggaactata aacggtggtc taattcaaaa
    10321 aagggattat tgaacaatca tcaaaacatt tacttttatt caaagtcaaa agattttaaa
    10381 tttaatacaa tttttacaga gtattcttct actacaaata tcgaccaaat actagtggaa
    10441 cgaaaacgag atggaaactc taaaactata tataaagttg ataataatgg taactatatt
    10501 ctagcaaaag agaaaaatgg agttcccctt tcagatgttt ggaatatacc atttcttaat
    10561 ccaaaagcta aagaaagagt aggttatcct acacaaaaac ctattctgtt attagaacaa
    10621 attataaaga ttgctactga taaaaatgat atagttttag acccgttctg tggaagtgga
    10681 actactttag tagcctccaa gattttgaat agaaattata tggggattga tttatctgag
    10741 gaagctatca atataactca gcaacgtctg gaaaatgtta taaaaacaag ttcagattta
    10801 ttgaataaag gaatcgaagc atatagaacc aaaactgagg aagaggaaaa cattcttaaa
    10861 ttattacagg caaaaattgt tcaaagaaat aaaggaattg atggtttttt acctaaacat
    10921 tttcaaaaaa aaccgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt
    10981 atctctttat tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa
    11041 actcattcag ataatttatt atttgatttt gatacgattc ctgaaaatat aatagtagtt
    11101 gaccattttg aacttacaat cgaaaaatgg ttaagtaaaa gtcaacagtt actatagttt
    11161 gcaaattatt tacagaaaga acaaaaaatg ctctgaaaca ctgatttcaa ggcatttttt
    11221 gttagtttaa aattactccc attcttcttt tccaaacata caatatatcc aaaaccattc
    11281 aaaatactag attctatttt ttataatatc actaaatcca cctaattata ggacgttttc
    11341 agatttttag tcccgtccca gtcccagtac cggagaaata ttgttttaat ataatatctc
    11401 tttttgtctt ctaagctctt aaaagcaaaa gaacaagtaa agagtcaaga caaggataaa
    11461 aagtccatat tagggcaaat aaaaagcttt aagacagatg acaaatctaa gtcaaataag
    11521 aaagaccata gcaaaggtgc agagagataa atattggcgg tcttcggact gcctttattt
    11581 ttttatccat ttttcaaatc aaatttattc agactatata tgcacatata cacttaaatt
    11641 catataaaaa catggcttgt aaaaaattac tttaatcaca ataatcgcat ttaaaattgt
    11701 gatgtttgca agctaaatta cggacttcac ttggaagttt tcccttgtat cttttataat
    11761 agatagaaaa tttgctggca gatgaatatc caacagattc tgctatctct tttataggta
    11821 gttcagtgtt taaaagaaga gtttcagcta cattcattct ttttctttga gtgtactctg
    11881 taatgctttg acaatatttt tccttaaata aattttttaa tttagtacca ctcattttag
    11941 atattttttc aagcgtgcct tgatttacat tcgttgcaaa atgatcatct aagaatcttg
    12001 ctacatcttc aagtgcttta tcatcatcaa tttcaatttt atattttttt ctatttaagt
    12061 atgtgtcaat tactatactt atccattcat ttgcctttgc tttaaagaaa aaatcagcgg
    12121 caggagcgtc catcttacaa tttaatattt ccattgccac tctttctaag gcctttgtaa
    12181 gtattatttg attcgattga agcaaggttg aataaaaaga ttctggatta atgttaatag
    12241 atgctaaatg tttttctatt agctcttttt taaaaccaat ggaaacagca agataacaac
    12301 aattctcgtg taataaaaaa acaaaatcat cttttatatt atcaaaatca aaagtacata
    12361 aagagtttgc ggtaatagtt tgatacggat taaacttttc tccgtttgca ctgacaatgt
    12421 aacttgaata aattgaaaca tagtctgaca tactataagt gctattttga actacttcct
    12481 ctttgatata aaaatcatgt atatcgataa tgaagctgcc tccttcataa aaccaatata
    12541 ggccttctgc ataagttgaa ttctcttttt tccaacaaaa tgtatgacct gcacttgaat
    12601 acttctcatt gtttttacat tcatctactt tcatataatc ttttacaaaa tcataatatg
    12661 acataacaca ctatcccttt tagacaatat tccaattagc cttattaatt caaaactatt
    12721 gtattagtaa ttataacaga tgtataatag aaaagcaatg atagatatta tcaattaagc
    12781 gaatttatat ctaaaaggga tattaaagaa aggagatatg cttatgaaga tttacaaaaa
    12841 actatttgct tatgtccaag ataagaaata tcttggggtt ttggccataa ttttttctgc
    12901 tatatctgct gcacttacag tatatggata ttatttaatc tacaaatttc tagataagtt
    12961 aataattaat tcaaacttat ccggtgcaga gagtatagca ttaaaatctg ttattacact
    13021 aacaagtgga gcgatatttt attttgtctc aggaatgttt tcacatatct tgggatttag
    13081 gcttgaaaca aatttaagaa aaaggggaat cgatggtctg gaaaaagcaa gttttaggtt
    13141 ctttgactta aatccatctg gtcaaataag aaagatcata gatgataatg cagcacaaac
    13201 tcatcaggtg gtagcacaca tgattcccga tagttctcag gcaataatca cacccgtact
    13261 tgtacttgca cttggcttta tagtaagtat aagggttggc ataattttgc ttgctcttac
    13321 tataattggt ggcttaattt taggggcaat gatgggcgag caagaattta tgaagatata
    13381 ccaagaatcc ctatctaaac taagtgctga aactgttgag tacgtgagag gaatgcaagt
    13441 tgtaaaaata tttaaagcaa atgtagagtc ttttaaaagc ttttataagg cgataaaaga
    13501 ttactcaaag tatgcttatg attattccct atcttgtaaa aggccttatg ttttgtatca
    13561 atggttattt tttggactga ttgcaatttt aattattcct atagtttatt ttatgactag
    13621 cttagctagc gcaaaggtga ttttacttga gcttatcatg attttatttt tatcaggagt
    13681 tctctttgtt tcattcatga gaatgatgtg gtactccatg tatatttctc aaggaaatta
    13741 tgcagtagat actttagagg cgctttacga agatatgcaa aaagacaaat tagtgcatgg
    13801 taatgtcaat aattttaaaa actataatat agaatttgag aatgttagct ttgcttataa
    13861 tgataaagct gtcattgaaa atttatcctt taatttagaa gaaggaaagt cctacgcact
    13921 tgtcggttca tctggatcag gcaaatcaac agtagcaaaa cttatatcag gtttttacaa
    13981 tgttaataaa ggaagcataa agataggcgg gatagcaata agtgaatatt ctgacgaagc
    14041 cttaattaaa gccatttcct ttgtttttca agattcaaaa ttattcaaga agagcattta
    14101 tgataatgta gctttagcta ataaagatgc gacgaaagat gacgttatga gagccttaaa
    14161 attagcagga tgcgatttaa tattagacaa attcccagaa agagaaaata caatcatagg
    14221 ctcaaaaggt gtttatttat ccggtggaga aaaacaaaga attgcaattg ctagagcaat
    14281 tttaaaggat tccaaaatta ttattatgga tgaagcatca gcatctattg acccagataa
    14341 cgagtttgaa ttgcaaaaag cttttaaaaa tcttatgaag gataaaacag ttatcatgat
    14401 tgcacacagg ctatctacaa ttaaagacct tgatgaaatt attgtcatgg atagtggaaa
    14461 aattatagaa agagggtctg acaaagaatt aatgtcaaaa gatacaaggt ataagagcct
    14521 gcaagagatg tttaacagtg cgaatgaatg gagggtttca aatgaaagag ttttataaaa
    14581 aaagatttgc tcttacagat ggaggagcaa gaaatttaag taaagcaaca ctggcttcat
    14641 ttttcgttta ttgtataaac atgcttcctg ccatattact tatgattttt gctcaggaag
    14701 ttttggaaaa tatgggcaaa agcaatggct tttatatagt attctcagtt ttgactttga
    14761 tagcaatgta tattttgctt tctatcgaat acgataaatt atataacaca acctatcaag
    14821 aaagtgcaga tttaagaata aggacagcgg agaatttatc aaaattacct ctatcttact
    14881 tttctaaaca tgacatttcc gacatttcac aaacaatcat ggctgatatt gaaggcatag
    14941 agcatgcaat gagccactca ataccaaagg tgggcggcat ggtactgttt ttcccattaa
    15001 tatctgtaat gatgctagcg ggcaatgtca agatgggttt agctgtaatt attccatcta
    15061 ttttaagctt tatatttata cctttatcta aaaaatatca ggttaatgga cagaatagat
    15121 attatgatgt cttaagaaaa aactcagaaa gctttcaaga aaatatcgaa atgcaaatgg
    15181 agattaaagc atataattta tcgaaggata ttaaagatga cttatataaa aaaatggaag
    15241 atagtgagag agtacactta aaggcggaag taactacaat tttaactttg tctatatctt
    15301 caatatttag ctttatatct cttgctgttg tgatatttgt cggcgtaaat ctaattatta
    15361 ataaagagat aaattctctc taccttatag gatatttact agctgctatg aagataaaag
    15421 actctttaga tgcatctaaa gagggcttga tggaaatatt ttatttatcg cccaaaatag
    15481 aaagattaaa agaaattcaa aatcaagatc tacaagaagg cgatgactat agcttaaaaa
    15541 aatttgatat tgatctaaaa gatgttgagt ttgcctacaa taaagacgca aaagttttaa
    15601 atggtgtaag ttttaaagct aagcagggag aggtcactgc tttggtaggt gcaagtggct
    15661 gcggtaaaac aactatcttg aaacttatat caagacttta tgattatgac aagggacaaa
    15721 tcttaatcaa tggcaaagat ataaaagaaa tatcaacaga atctcttttt gataaggtct
    15781 ctatagtttt ccaagatgtg gttctcttta atcaaagcgt tatggaaaat attagaatcg
    15841 gaaagcaaga tgcaagtgac gaagaggtta aaagagcagc aaaacttgca aattgcacag
    15901 attttataga aaaaatggat aaaggtttcg atacagttat tggtgagaac ggagctgagc
    15961 tatcaggagg agaaagacaa agattatcaa tagccagagc cttcttaaaa gatgcgccga
    16021 tattgatctt agatgagata acagcaagcc ttgatgttaa caacgagaaa aagattcaag
    16081 agtctttaaa taatttagtt aaagataaaa ctgttgtaat catttcacat agaatgaaat
    16141 ccatagaaaa tgcagacaag atagtagttc ttcaaaacgg aagagtagaa agcgaaggta
    16201 agcatgaaga gcttttacaa aaatcaaaaa tttacaaaaa tttaatagaa aagacaaaaa
    16261 tggcagaaga atttatttat taggaggact acaatggata ataaaaaatt aaaagtaaaa
    16321 gatttagtaa gcatcggtgt ttttggcgta atttattttg ccttcatgtt tggagttggt
    16381 atgatgggct tgattccaat attgttctta atatacccga cagtattagc catagttgca
    16441 ggaactgttg ttatgttatt tatggctaag gttcaaaagc catgggcact atttatattt
    16501 ggtatgatat caccacttgt gatgtttgca gctggtcata cctacgtagt tgtggtttta
    16561 tcacttatag taatgataat agcagaatta attagaaaga ttggtaatta taattcattt
    16621 aaatacaata tgctttctta tgcaatcttc agcacatgga tatgtagctc tttaatgcaa
    16681 atgcttttag caaaagaaaa atatatggag tggtctttga tgacgatggg aaaagattat
    16741 gttgatgtat tagaaaagtt aataacttat cctcacatgg ctttagtagc cttaggtgct
    16801 ttcttaggag gaattcttgg agcatatata ggcaaggctc tattgaaaaa acactttgaa
    16861 aaagcaggca ttgtataatg cctacttttt cttcaaatgc tccctttaat cccaatccga
    16921 tctctaagat attagtcgta tttatcacag gcttaactgt tatgcatagc ataaacatcc
    16981 gttttgagct ggcaattgtt tgtcttattg gtattttgct ttatttgaat ggatacaaaa
    17041 aaacactttt caaatggatt atattgtgtg ggatacttta ctccttgcct aattttatgg
    17101 tgttatctga attaaaccct atagttaaga tgtttttgag tatacctatt gttattagaa
    17161 tgtttatttt accatttatg gcagcaagct ttatgataaa gacctcggat gtaggcgcaa
    17221 taatttcatc gatggataag cttaagattt caaagaatgt atccatacct attgcggtta
    17281 tgtttagatt cttcccatct tttaaggagg agaagaaaaa catcaaaatg gctatgagag
    17341 taagagggat aaattttaaa aacccagtca aatatcttga atatgtttct gtgccactac
    17401 tcattatatc atctaatata tcagatgaca ttgcaaaagc ggcagaaaca aaggcaatag
    17461 aaaatccaat tgccaagacc agatacattc gcgtaaagat acagctaatt gattttgttt
    17521 atgttttagc ggttgttgga cttattgtgg gaggcttaat atggttgaaa taaaaaattt
    17581 aagtcttgat tatggtgaag agcatatatt agatgatata tcactatcca tagccgaggg
    17641 agagtgcgtg ctatttacag gaaaaagtgg aaatggtaag tcatctttaa taaattcaat
    17701 caatggacta gctgtaaggt atgacaacgc aaagacaaag ggcgaaatca ttattgatgg
    17761 taagaatata aaaaatttgg aactttatca aatctcaatg cttgtttcaa ctgtttttca
    17821 aaatcctaag acatattttt ttaatgtcaa tacgacatta gaattattat tttatttgga
    17881 aaatatcggt cttgcaagag aagagatgga caggcgtttg aaggatatgc ttaagatatt
    17941 cccgataaaa aatcttttga acagaaatat atttaatcta tccggcggtg aaaaacaaat
    18001 tctttgcatt gcagcttctt atatagcagg tacaaagatt atagttatgg atgagccttc
    18061 atcgaattta gatattaaaa gcataagtgt tttggcaaag atgctaaaga tattaaaaga
    18121 gaaaggtata agcataattg ttgcagagca tagaatttat tatttgatgg acatagttga
    18181 ccgtgtattt ttaatagata aaggaaagct taaaaaaact tatactagaa gtgaattttt
    18241 aaagctagat aaaaatgaat taaatgcttt aagtttaaga gataaagaat taagtaaatt
    18301 aaaagttcct tatttaaaag aaggtggaga gtatcagata aaaaatctta gctacaaatt
    18361 tactgatgat gagtgtttaa gcttaaaaga tatttcattc aagcttggga aaatttatgg
    18421 cataatagga tccaacggac gaggaaaatc aacgctttta agatgtttaa taggtcttga
    18481 gaaaaaatca aaagaagaaa tttattttaa gggagagaag ctatctaaaa aagaaagact
    18541 caaaaactct tcacttgtta tgcaagatgt aaatcatcaa ttattcacag atgaagtatt
    18601 caacgagctt agattaggag taaagaattt tgatgaagaa aaggcgaaaa tcattttaaa
    18661 agatttaggc ctggacgaat ttattgaaag gcatccgatg agtttatcag gagggcaaaa
    18721 gcaaaggctt gcaatagcat ctgttatgtg caagacttct ccatttgtct tttttgacga
    18781 accttcaagt ggtatggatt attccaatat gataaaaata tctgaactga ttaataagta
    18841 taaaaccatg gataaaataa tttttattgt ttcccatgat atagaatttt taaatgaagt
    18901 ggcagatgaa atttttgaat tgtaaaatag agtctgttaa acatgtctat agaactagta
    18961 aattgtctaa aaatttaaaa gatactaaca catattgata tttattagaa aattaacttc
    19021 aggattttta cagtatttat aaactttata atatgtattt atagtattaa taatttccat
    19081 atctttaggg aaattcttta tttacttacc ataattaaag agatgagaga taaatatcgg
    19141 cagtcttcgg actgccttta tttttttact taatttaatg cagtaaatca tacgattgaa
    19201 aggaatctgc gttatatgct ataattaggt ggttaatcta tacatttaga aaggtaaaat
    19261 atagaattgg agaatgatat gggattttca tataataaat tgtaaccgtc caataacgaa
    19321 gtatattgaa aaatctccag actagagaac t
//
LOCUS       DAVBOU010000041        18510 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBOU010000041 DAVBOU010000000
VERSION     DAVBOU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18510
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.041"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..365)
                     /locus_tag="VQ879_001585"
                     /pseudo
     CDS             complement(1..365)
                     /locus_tag="VQ879_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(441..875)
                     /locus_tag="VQ879_001586"
     CDS             complement(441..875)
                     /locus_tag="VQ879_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143713.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(951..1801)
                     /gene="rfbD"
                     /locus_tag="VQ879_001587"
                     /pseudo
     CDS             complement(951..1801)
                     /gene="rfbD"
                     /locus_tag="VQ879_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1867..2916)
                     /gene="rfbB"
                     /locus_tag="VQ879_001588"
     CDS             complement(1867..2916)
                     /gene="rfbB"
                     /locus_tag="VQ879_001588"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3143714.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2926..3522)
                     /locus_tag="VQ879_001589"
     CDS             complement(2926..3522)
                     /locus_tag="VQ879_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3143715.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3523..4380)
                     /gene="rfbA"
                     /locus_tag="VQ879_001590"
     CDS             complement(3523..4380)
                     /gene="rfbA"
                     /locus_tag="VQ879_001590"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3143716.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
     gene            4594..5900
                     /locus_tag="VQ879_001591"
                     /pseudo
     CDS             4594..5900
                     /locus_tag="VQ879_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6188..6370)
                     /locus_tag="VQ879_001592"
     CDS             complement(6188..6370)
                     /locus_tag="VQ879_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143717.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(6586..7818)
                     /locus_tag="VQ879_001593"
     CDS             complement(6586..7818)
                     /locus_tag="VQ879_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3143718.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(7847..8917)
                     /gene="gla"
                     /locus_tag="VQ879_001594"
     CDS             complement(7847..8917)
                     /gene="gla"
                     /locus_tag="VQ879_001594"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3143719.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(8985..10154)
                     /locus_tag="VQ879_001595"
     CDS             complement(8985..10154)
                     /locus_tag="VQ879_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3143720.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(10340..11644)
                     /locus_tag="VQ879_001596"
     CDS             complement(10340..11644)
                     /locus_tag="VQ879_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3143721.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(11761..12915)
                     /locus_tag="VQ879_001597"
     CDS             complement(11761..12915)
                     /locus_tag="VQ879_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3143722.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(12912..13463)
                     /locus_tag="VQ879_001598"
     CDS             complement(12912..13463)
                     /locus_tag="VQ879_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3143723.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(13456..14592)
                     /locus_tag="VQ879_001599"
     CDS             complement(13456..14592)
                     /locus_tag="VQ879_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3143724.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(14733..15398)
                     /gene="cpsD"
                     /locus_tag="VQ879_001600"
     CDS             complement(14733..15398)
                     /gene="cpsD"
                     /locus_tag="VQ879_001600"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3143725.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVS
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(15408..16100)
                     /gene="cpsC"
                     /locus_tag="VQ879_001601"
     CDS             complement(15408..16100)
                     /gene="cpsC"
                     /locus_tag="VQ879_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3143726.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(16109..16840)
                     /locus_tag="VQ879_001602"
     CDS             complement(16109..16840)
                     /locus_tag="VQ879_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3143727.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(16842..18287)
                     /locus_tag="VQ879_001603"
     CDS             complement(16842..18287)
                     /locus_tag="VQ879_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3143728.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         5961 a         3783 c         2706 g         6060 t
ORIGIN      
        1 aggaccagat gtccgtcttt caaaatagtc ttaaaggttt cttcatactt gaggctgtat
       61 tcaattgccc ttcctagttt tgaacctgct aaaactgact gacgccggca ccaagcaaag
      121 aagtcttcca ttaggggctg gagatgttct tgacgtttct gtagtcgttc atcagctggc
      181 aaagcctccc agtctctttc caaggaaaat aactgatcac aataagctaa acctttagct
      241 cctaaggatg atttatccgt ttgcttgggg ggcgcttcaa aaaacttcct tctcacatgt
      301 gcccaacatc caacaagttc agcttcttcc agttgacgat aagcttctag cggttcgcag
      361 tttaccaagc ttagcgtcgc cttgctccta aaccttggac tgctatcgca taggcagaac
      421 tagaggacta aagtcctaag ttactgccgc aacatatcac aatgcacata gccagaataa
      481 tctcctagga attcttgtac tactaaacca ctccgacgct gatcatggtg gtacagcgtg
      541 attgcttgat tctcagcttt cccagacaaa aaagtccaat agtaggtcag atggctatca
      601 ctctctagaa cccgataaga ggtttcatcc gcatgaagaa gaggttgttc taacaacttt
      661 tctcgtaaaa ggttataaag ggactctaaa tagtattgac ttgccttgat atgccaatta
      721 gagatttcct tacgtgtgat tggtaaaccc atcctagccc aatcttcttc ttggcgataa
      781 ttgggtacct tcagattaaa cttctgatgg atggtgtgag cgataataga aactgagcca
      841 aagctatgca ccaaagagac cagcaccaac aacaagataa ttgtacatct taagctcctt
      901 tggagttcat tatctgcctc ttttattaga ctagaaaatc attctactac ttatctcact
      961 tcttgtttgt aaaattcttg caatgcatct tgccaagttg gaataacaaa tccagtagct
     1021 ttggctttgg ccaggctcat cgttgagttt agcggacgtt gagctttggc tggaaattga
     1081 ctggatctac tggcttgact tcgacatctg tatctttcaa aatttcaact gcaaaatcat
     1141 accatgttgt gtcttctgtc gcatcatttg acaaatgata ataaccaaat tccttacgat
     1201 tttcagctag gtagatcatg aattcagcca aggtacgagt ccaagtcgga cgaccgtact
     1261 ggtcatttac aactgttaaa gtcttatgag ttttcgcaag attttgcatg gtaaaaacga
     1321 agtttttgcc ataatttcca aatacccagg cagtacggat aatatagaaa ttagacacat
     1381 gcttctcaac taactcttcc cccatacgct tagtgcgtcc atattctgtc tgtggatctg
     1441 gtcggtcatc aacttcccac tcttgtccaa ctggtttctt accgtcaaag acctagtccg
     1501 tagaaatata aactagagtt gcaccatgct tttcagatgc ttttgcgaca ttttttgtcc
     1561 ccatcacatt gatggcgaag tccaactctt ttccttcatc ctctgctgca tcaacagcgg
     1621 tgtaggctgc acaatggtag actaaagtcg gtttcacctc ttcaaaaact ttctcaacca
     1681 tttcttcatt ggtaatgtcc atctcagcca catctactgc cacgtattct tcattacgtt
     1741 catccaataa atagcgaagt tccgttccta attggccatt tgcccctgta attaaaatca
     1801 tctctagacc tttctaatat gtaactcttc ccaatatagc aataaaaagc agcgatttcc
     1861 tgctttttat actgtaataa tctcctgagt cttagcataa ttggcttcaa cagcttcttt
     1921 ttctgctttc caccattctt ggttatctgt ataccacttg attgttgcct tgagcccagc
     1981 ttcaaagttg gtaaattcag gtttccaccc caactcatca cggagcttgc tggcatcaat
     2041 cgcatagcga aggtcatgtc ctgcacggtc agtcacatga tcataggcat ccgtagcttg
     2101 tcccatttcc ttaaggataa gttccaaaac ttccttattg ttcttctcac catcagcccc
     2161 aatcaagtag gtttcaccga tttgcccttt tgtcaagatt gtccaaactc ctgaagaatg
     2221 gtcattggta tgaatccagt cacgaacgtt cttaccttca ccgtaaagtt ttggcttaat
     2281 tccacttagg atgttagtaa tctgacgtgg gatgaatttt tcgatatgtt gataaggacc
     2341 gtagttattt gaacagttgg aaatcgttgc cttgactcca aaagaacgca cccaggcttt
     2401 gacaatcaag tctgatgcgg ccttggttga tgagtacgga gagcttgggt tgtattttgt
     2461 ttcagcagta aatttctcac ctggtccttc accatgacct ggcaaatctt ctcgtaaagg
     2521 gagatcccca taaacttcat ctgtcgatac atggtggaag cgaatatcat acttacgagc
     2581 agcttctaaa agagtataga ttccaatgaa gttagtatga ataaatggcg atggatcatt
     2641 gagcgaatta tcattgtggc tttccgctgc ataatgaacg atagcatctg cttgagcaac
     2701 caacttgtct accaactccg catcagcaat gtcaccaaca actaactcaa cacgattgcc
     2761 taaaatttcc tcaatattcg cgcggtttcc agcataagtc aacttatcta ggactgtcac
     2821 gtgaacatct ggaaagttct cgtaaacata atggacaaag ttagaaccga taaagccagc
     2881 tccacctgtc acgataatat ttttgtattc agtcatattc tttccttatt ccaaatcttc
     2941 ttttttcaaa ggcttcacgt ccttaagtag gggatgatgt ttgtctgctt cagatacgtc
     3001 tgcttcttcc agattttccc attcaatacc aaggcttgga tcagcgtagt tcacaaaggc
     3061 atacttgggt ttgagttcaa gagcccagta atcattgacc agatagctat atgacactgt
     3121 atctgataaa acttggaagc cattagctac gcctcgagga acaaagattc ccttgcttgc
     3181 atcaattact gtctgatagg tattcccaaa ggtttcaccc tcgcgtagat caacccaaga
     3241 acccagaact ttccctccat ctgctacaga gatgtactta tcccaaggct ctgcgtggag
     3301 gcctcgaagg acatttttac gtgagaagga tacattgttt tgcaattttc cttctgcaaa
     3361 gaaagactct ggaaatccaa gtggaagcac tttttccttt tggaaatttt ctttaaacca
     3421 gccacgatta tctccatgaa cggggatatc aaactccaac atgcctggaa tagcttcaac
     3481 cttgcgtgcc gcaagcgtct taccgaaaaa attatctgtc atctatgctt ctccaatcaa
     3541 acggagcaga tactgtccgt attcattttt cttaagtggt tgggctaagg ccaatacatc
     3601 ttctcgactg atatagccca tacggtaagc aatttcttct aagtttgcta cctgaacatt
     3661 ttgcatccgt tgcactgttt cgatgtactg tgaagcctct agtaaacttt catgagttcc
     3721 agtattcagc caagcaaagc cacgtcccat aagctcaaca gacaaatcac cacgatctag
     3781 gtaaaccttg tttacatctg taatttccag ttcaccacga gggcttggtt taatactctt
     3841 ggcaatttcg acaacatcgt tatcatagaa atacagtcct gtcactgcat agttggagcg
     3901 aggatactcc ggtttttctt ctatggaaat agcattcatg tctgtatcaa actcaaccac
     3961 accaaaacgc tctggatcct tcacttggta gccaaaaaca gtcgcacctt tctctttctt
     4021 ggctgctttt tgaagcattg tgctcagacc aggaccatgg tagatattgt cgcctaaaat
     4081 caaggcaacg ctatcgtcag aaataaactc ttccccaatt gccaaaccat ctgtacttgg
     4141 ttgctctgca taagaaagtt tgatcccaaa ctcagatccg tcttgaagaa gctcttgaaa
     4201 tcgatgtaaa tcctgtggag tggaaataat caaaatatcc ctaatcccag ccaacatcaa
     4261 tgttgaaagt gggtagtaaa tcatcggttt atcataaacc ggcataagtt gttttgacgc
     4321 agcgcgagtc aaaggatata aacgtgtccc cgaaccacct gctagaataa tacctttcat
     4381 agtagggtac ctttctttgt tattttagag tcaattacta ttaattgtgt actgctctaa
     4441 aaagaaaaca atcatcccat gttttatatg gctctataat atttgtagtg ggtaaatccc
     4501 ttatagatat tatggagcct attttgttgt agaaaaaaag tcccatatga cctataatga
     4561 aaagcgacca aacaactcat tagaaagatt catatggaac aattacattt tatcacaaaa
     4621 ctgctcgata ttaaagaccc aaacatcaag attctagata tcatcaatat ggatacccac
     4681 aaagaaatta tcgctaagct ggattatgag gctccatctt gccctgattg tggaagtcta
     4741 atgaagaaat atgactttca aaaaccgtct aagatccctt atcttgaaac gactggtatg
     4801 cctactagaa ttctccttag aaagcgtcga ttcaagtgct atcactgttc aaaaatgatg
     4861 gtcgctgaaa cttctatcgt caagaagaat caccaaatcc ctcgtatcat caaccaaaag
     4921 attgctcaaa agttaattga aaagatttct atgactgata ttgcccatca gctttccatc
     4981 tcaacttcaa ctgttattcg taagctcaat gattttcact ttaaacatga tttttcttgt
     5041 cttcctgaga ttatgtcttg ggatgagtat gcttttacaa agggaaagat gagcttcatt
     5101 gcgcaagatt ttaacaatct caatatcatc actgttcttg agggtagaac acaagctatc
     5161 attcgaaatc actttcttcg ctacgataga gttgtccgat gtcgcgtcaa aatcattact
     5221 atggatatgt ttagccctta ctatgacttg gctaaacagt ttcgctttca aatttctagg
     5281 ctcaggctga aacagtctcc cagactgttt cactcccgaa tgctaaaatc gtgttggatc
     5341 gctttcacat tgtacaacat cttagccgtg ctatgagtcg tgtgcgtgtt caaatcataa
     5401 atcagtttca tcgaaaatcc catgaataca aggctatcaa gcgctactgg aaactcattc
     5461 aataggatag tcgtaaactg agtgataaac atttttatcg tcctactttt cgtatgcatt
     5521 gaaccaataa agagatttta aacaagcttt tgagttattc ggaagacttg aaacaccact
     5581 atcaactcta tcagctcttg ctttttcatt tccagaataa ggaaccagag aaatttttcg
     5641 gacttattga ggacaatctt aagcaggttc atcctatttt tcagaccgtc tttaaaacct
     5701 tcctcaaaga taaagaaaag attgtcaacg cccttcaact acactattct aacgccaaac
     5761 tggaagcgac caataatctc atcaaactta tcaagcgcaa tgcctttggt tttcgaaact
     5821 ttgaaaactt caaaaaacgg attttcatcg ctctgaacat caaaaaagaa aggacgaaat
     5881 ttgtcctttc tcgagcttag ctgacttcaa cccactacag ttgacaaaga gcctaaaaat
     5941 tcacttactt catattacat ttagcatgaa atgaaataag cgaattctac tttgtttgca
     6001 tacaattaaa aatcaattcc taaggatgtt ttaaataact gtgtaaaagg cataatttca
     6061 ccatttctta gtttttcaat gctaaattac atagtaactg gagagctatt agaaatctct
     6121 aacttcctca tagttaaaaa atgacaatga gatacttatt gatttcaatt cattaacaga
     6181 atacgaacta gacaagtgag ttcgtctcct taacaaacac ttccaagcgt ttactttcct
     6241 cattcagtcg tcgtaatcta caacttacat catcagataa gtcatactca ccatttagaa
     6301 tagatagaat atgttgtttt tcttcttcag tcttctcttc aataagcaca tttttaaaaa
     6361 ttactgccat tatcagcacc tcacttcgaa ggaatatatg caactatatc ctattaagtc
     6421 aatctctact gacaaaagaa gtatatttac ttcactaagt gcgagcgaga atatagaaat
     6481 atctttattg ttttagatga gttgtcgcta tcctccagct agtttttaac tattctatca
     6541 ttcaaatgat atagattatt agggactaga aatatacaaa ttgatttaat ctctcttaaa
     6601 aatatcccta gtataaactt tacccctcac atcttctaaa gtctcatcaa aacgatttgc
     6661 aacaatcact tgactagatt tcttaaatat ttcaaaatca ttaactactt gactaccata
     6721 gaaagtagta ccactttcaa gagttggttc gtaaataata atagtaacac cttttgcttt
     6781 caaacgcttc ataatacctt gaatagaaga ttgtctaaaa ttatctgaat tacttttcat
     6841 tgttaaacga taaattccta caacaatctc tttttcttta tctggtttat agaaatcatt
     6901 gcctacataa gatccagcaa gatctaaaat acgatctgca atataatctt ttcttgtccg
     6961 attactttgt actatagctg ttatcatttc ttgtggaacg tcagaataat ttgcaagaag
     7021 ttgcttggta tctttaggaa gacagtaacc cccataacca aaagaaggat tattgtagtg
     7081 agaacctatt ctcggatcta aacaaactcc atcaataatc gcttgagtat ctagtccttt
     7141 catctcagaa taagtatcta actcgttaaa ataggaaacc cggagggcaa gataggtatt
     7201 agcaaaaagt tttactgctt cagcttctgt aaaatccata tacaatgttt caatattttc
     7261 tttcactgca ccttcctgaa gcatttttac aaaaatttca gcagacttta ccaaatcttt
     7321 atcatcttta tctgtaccta taataattcg actcggatat aggttatcat ataacgcttt
     7381 tgactcccgt aaaaactcag gactaaacat aatattgtct gtaagaaatt tcctccgtac
     7441 tgactttgta tatccaacag gaacagtact tttaattatt ataattgcat caggattata
     7501 tttcataact gcttcaatga cagcctcgac tgaagatgta tcgaaaaaat tttttttcgg
     7561 atcataatta gttggagccg caataactat aaaatccgca ttctcatatg cttcctctgc
     7621 attcaatgta gctacgagat tcaattcttt ttccgcgaga tatttttcta tataatcgtc
     7681 ttggataggg gacttctttt tattgattaa ctcaactttc tcaggaatga tatctacggc
     7741 aacaacttga tgatgttgag ccagtaagat tgcaatagat aatccaacat atcctgtacc
     7801 tgctactgct attttcataa ttttttcctt tctcaaaaca ctctcgttat acattatagt
     7861 agtctttata ccactctgca aactttctca aaccttctcg taaagaagtt tttggtttaa
     7921 aaccaaaatc tctctctaaa tcacttgtat ctgcataagt aacaggaaca tcgcctggtt
     7981 gcataggaac taatttttta tgactatcaa aatcataatt ttccggcaaa actcctgcct
     8041 tgattagctc ctgttgaaga acatccacaa aatctaacaa attttcgggt ttactattcc
     8101 caatattgta cactttatat ggggctaacg gtaaattatc agatcccact agtttcttcg
     8161 gagctgattg catgaccctt actatcccct caacgatatc atctatataa gtaaaatctc
     8221 gtttacaatt accatgatta taaatctcaa tatcggaacc acttcgcaat ttatctgtaa
     8281 atccaaaata ggccatatct gggcgcccag caggaccata aactgtaaaa aagcgtaagc
     8341 ctgtcgaagg aatattgtaa atctttgaat aagcatacgc ttgaagttca tttgtttttt
     8401 tagtcgcagc atatagtgaa ataggattgt ctaccttatc ttctgttgca aacgggattt
     8461 ttttatttcc accatatacc gatgaggacg atgcataaac taagtgttcc acaccaccat
     8521 catatatctc atacgaatga cgacaagctt ccaacacatt atgaaagcca acgatattac
     8581 tttctatata tacatctgga tttgtaatgg agtagcgtac tcctgcctgg gcagctagat
     8641 taacaacaat ctgaggatga taactcttaa aaatcttatt aataagcatt ttatctgcaa
     8701 tatcaccctt gataaatatc cagttttttt ctggataatc ctgaattagc ttattaagtt
     8761 gaagcaatcg ataatcttta agtgcaatat catagtaatc attcaaattg tccaaaccaa
     8821 tgattgtcat cgttccttct aattccaata atttcctaac cagatttgat ccaataaaac
     8881 cagctactcc tgtaattaga attgtttttc ctctcatatc ataatacctc ttgttatttt
     8941 tatattttca tccactaata cacattcttt aacaactatt ataatcaatt tctaagataa
     9001 tctataataa aaaacaaacc acatacagta taagagattg ctgatgctat cgcagctcct
     9061 gtaatttggt agttaggaat taagtaccag tttaaactta tatttatcaa agccgacaca
     9121 gataaaattt ttatagctac actctgttta ccctgagata tataaattgg ttgtaaaatt
     9181 ttaaagaaaa tcatcgataa gcttcctaaa aaaatgacta atgttatagg aaatgccttt
     9241 atataactgg aaccataaag gagcgtaatc gcaaattctc caaaagaaag aaatccaata
     9301 attaataaaa tcataaatag aaatgatact tttattgcat ttattgcttt atttttctca
     9361 aaagttcttt tagccgaatc accaaataaa atctctttaa atgagtctgg aaccatcaaa
     9421 aacatattag aaaacgtaac tgcgacactg tatataccta cattataact actagacatt
     9481 tgcttcaaca ttatgatatc aatactataa ttaaatgtaa ttaatagagt aagaatcata
     9541 gaaagaaatc caaacttata tatagtgaaa aattctttaa tactaatatg ttcaaaaact
     9601 gggaacatat tgtaatagta taaaaataaa atgatacgta aaaattcatt aatagcatat
     9661 accaaaaata ccatctctat agaaactaaa tgaaatagta acaacaatac tagcataacg
     9721 gaatatacta cgcttactcc taatacaatc ttattcctct ttatactatt ttctattact
     9781 gcaatcatag taagatttgt tctcataata gatagactgg acaaaactat tattacccca
     9841 ccataatcta tcggaacatc agctaaaact attattaaac ctattattcc aaacaataat
     9901 ccttgaataa aagttaaaaa aacaaattta ttctgatact cattagaatg attcctttta
     9961 aaggtcgagt aagcctgacc taaaccaact ccacctaaaa tataaaaaat ttctactaag
    10021 ttcattacat aggcataatc tccttttttt tcaacaccta atcccctatt aattataatt
    10081 gaggataaaa gtgttaataa gattaacaaa aatttactcg ttaaagcaaa ccaatatttc
    10141 ttagatagtc tcacttattt tctccgtatg ttaaatttta taacagtaaa tttaaaatta
    10201 tagtatattg aaatagaata tgaacaaaac gattagggaa tttaaagtaa tttataaaaa
    10261 ttctttagaa gctgcattgt actactccaa cttcaaacca ctatagtatc aaaaagtata
    10321 ccccaccttt ttaaataaac tactcaccac ccatttcatc caatggtgat atcaacacca
    10381 ttctattgat aaaaacaata accaatgttc ccaatatagc atatttaagt aatggagata
    10441 atatgttagc aaaatcagca cgagtagaat aaataaaaat aggtatcata tacagatata
    10501 tcagcatccc gtatatattt ctttgagcgt ttatataaag aaatctcatc aaaaagcctg
    10561 ttagcataaa aatcattaca attccaaagt atcctccatt cacatatccc tctcccacaa
    10621 gagtaaaacc atatttggtt gaatgtacgt ttggaaaaaa ggtgtccata aaccaagttt
    10681 gattagaata ccccgtatta taaaaaattc ttactatgtc attaaaaaaa gaacgacctt
    10741 cgaaataatt gcccatatta tgtaatatca gaatctgtaa attacgacta gctgatacaa
    10801 actcaccatc tagcaaatca aaccaaatat tatttgtatt tatagatgaa acttgcccac
    10861 ttaataaagt atatttaaaa actgcagata acggaatcag tagtgccgca agcggaacta
    10921 acattacaag ataaaaacgt tttattttgt gaaagtaaaa taatataatc acatcaagga
    10981 tgaataaagt aaacatataa tctctttccc ctgtaacgat agagaagaga cagataacta
    11041 tcgctgtgtt agtattacaa tttagtagtc tccatttttt agtactcaac tgtataaata
    11101 gctgatatgt atgaatgaga atcataaaat aaaccaaaga aaatactaac attatcacaa
    11161 tattggcacc tgaatatatt tcccctttat ttctaaaacc acttcctaat agatatataa
    11221 ttgctactgt tgtgataaac gtattcatat tattgagaaa taataaatag ttattgttat
    11281 ttaggtttat tttcctttcg cttaacacaa tggctttaga aggtagagtt aacaacaaag
    11341 ttgccaaagc cagccattgc atgaaaatca aatcttttgt ataaccatag tttatatact
    11401 ccattctata gagtagcggg taagaaatag aataaatagt aaagaagcta ctataccaca
    11461 catagggatg aaaaatatta aatttcacaa ttatcattgc cataaaactt aaaaaaatca
    11521 ttgaaaataa tggaattgta acatcattat tttcactgca taaaattaaa gtccctgaaa
    11581 aaactacacc tactagaagt attattttat tttttatatc atttgattgt agactaaact
    11641 tcatttactt ttttccttta actaataatt taaacgtaat gcgtattcaa aaatttgatt
    11701 ggctatgtag tcagttttta tagcatattt aatatatcga aacggatttt ccatcgcatt
    11761 ttaatctaaa ccatcagaat tatttaattc tcttctaatt tgagcaaaat agtcacttct
    11821 gcgtttattt aatacactcg aaagaaattt ttttgagaat tcaaactgtt ttatcaccat
    11881 cttttcctta tccatactaa taaaatctat aatagatccc gcaatcgctt gtgaagagga
    11941 tggagtaaat agacaatgtg gccccagcaa ctctggaatt cctgctttat tagaccctat
    12001 acaagggcaa gcacggctca tagcttcaat taccgcacga ggtaaccctt cttgtaaact
    12061 tggttgtata tataaatcaa ctttatccaa atactcataa atttgtgatg tagtcaattc
    12121 ccctaaaaaa tggattctat tcgctactcc caattcctct gctttctttt ttaagaaact
    12181 ttgatcacca tcacctgcta aataataatc caacaaaata ccttgtattt ctaatctctt
    12241 cattgcttcc aatacaaatc tatggccctt ggctcgtaca ttcacagatg ctgttgtcat
    12301 tattgaaatt ttttgaggat taaatttttt caacttataa agacggctct tcaaagatct
    12361 attctctaca gaggtaatat taacatttga agcaacgata ttagatttaa tattaggata
    12421 tctatcttgt aaatattttt ctgtcacgta tatgcaataa ttagcgtttt ttacaattga
    12481 tttagttttg gcgtatatat atggagctaa taattttccc tttaaactat gataccagta
    12541 agaatcccaa gcatccccca ttatttctgt cagatacggc ttacctatct tcaatgcgta
    12601 gtctgcagtt tttgatccaa ttatagacgg aatacgaaca actattaagt cgctatcaat
    12661 cattccttca ataatcttat ttttattttg accaaataga acctgatgta gaccttctat
    12721 agggataaat ttattaataa agttcgcttt atgatatcct tcagggtatg attccacctt
    12781 ctcataacga ctacatagta caatctctcc aaatgcttta gcatagcgct cataaataaa
    12841 ataagctttc ggttttaaat atatttcatt tttatagatt gtacatctaa attcagtcgc
    12901 tataaatact ttcataattt catctccctt gataaacgtt tctgaataaa tatagtatca
    12961 gctggaatat cctttgttac aacacttcct gctgcaacca cactattctc accaatactc
    13021 actcccttca agacaatgct gttagctcca atccaaacat tttctccaat cataactggg
    13081 gccgtcttaa atttttttgc tttcaatcca cctggaacac taacatcata gtcatgatca
    13141 tatataagta ctccaggacc acattttact ccagatttaa tatctatgta tttacgacaa
    13201 gctatcatac aattattact caaaaataca tcatcagaaa tcttgagttt tgctcctttt
    13261 ctaactttca atactccccc ggcgtttact ctaatctttt ttcctaagat taatttagca
    13321 ttagattcct gttcgacagt tacattcttt ccaaatttta aaaaataatg aaaagtaaga
    13381 tccttgtttc gacacacttt taataatatc aagcaaatat ttgcacgaag taaaccaaca
    13441 atatttttta taatcctatt catctaaagc tccttttatt ttatctaaat aagcatctat
    13501 aataatttga cgagaaaaat attgctctat atacattctc ccttgaagtc ccatctcttt
    13561 tcgtttttca ttttctagac ctaaaaaaac ttccaatata gagactagtt cctcaacatt
    13621 tcccccttga aatatatagc ctgtctctct atctttaaca atttctttgc aacctggatt
    13681 atctgtcgta attaaaacac gtcctgaact agcgttttct agtaatacat tgctcattcc
    13741 ttcaccatac acactgggat ggataattgc atgggaacgg gtaatatgag gtatcacatc
    13801 tttttgttgt cccaaataat aaacgattcc ttttttttct aagtcacaaa ttttaagttc
    13861 ataattactc tctgtcggtt ctataaagcc aataatatta aactctgttt tgggatatcg
    13921 actcttaata atttgggcag cagccagata agtatctata cctttttctt ttaatatcct
    13981 accaataaaa ttaaaaacga ttgtttctcc ttgaattcca tttccaccat ttggatactg
    14041 ttgcacagga tacttttcaa tgttcactcc tgacccaggt atcagcttag agtcacccaa
    14101 aatcaagcca agagttttta acattttcat attatattca ttttgaaaaa aaacacaatt
    14161 tgatttccta aaagaaattc taaacagtaa taacaccagg cttcttacac aagaacccat
    14221 tgttaagaca ctacctaaac ctgttacgtt atttatatat tttattccta aaattgttgc
    14281 agctaggcta gcatatacat ttggtttcac ggtatatgtc aagactacat ccggtctata
    14341 ttttctcaat aatcttatat aactaagaaa tagacgaata tcttttaaag ggtttattcc
    14401 tcttctatca atagtaatat cttcatactc aaattgaata gacttcatca actctatctt
    14461 atctccataa ggacatgaca ctagcacttc atacccatac tcaactagtg actctataac
    14521 ttcttttcga aaacaataga tatcatcgtc atgattagtt attaacataa tttttttctt
    14581 ttgtaaattc atcaaaataa tcttcctaaa atataattaa ccgctactcc attatccttt
    14641 acaactatca ttttaaaaat agtaattttc tataagtaat tgtttccaaa ttgtgacact
    14701 ttaaaattct atacacatat agaacttaca aactatttac gaccgtaaac tccatactta
    14761 tcaaccgaga tatccaattt atttaaaaca actcccagga acagtttccc tgtttgttct
    14821 aattgttgtt tcgctttttg gacatcacgt ttattcgcct cacctgttgc tgttatcaag
    14881 atggacgcat cacacttttg agtgataatt gccgcatcaa taacaattcc aataggtggt
    14941 gtatcaacaa tgatataatc aaaatattta cgcaatgttt caatcatatc attaaaattt
    15001 ttactttgta acaaggctgt agggtttggt gatacagatc ccgattgaac tacaaataaa
    15061 ttttcaatat ttgtatcaca taaaccgtga gataaatcag ctgtcccaga taaaaattct
    15121 gttagccctg taattttttc acgagattta aaaaatcctg acataactga atttcgaata
    15181 tcgccatcga acaaaagagt tttatagcct gcacgcgcaa atgacattgc tatatttacg
    15241 gaagtagttg tttttccttc ccccggacta acagaagtaa cggaaattac ttttagttta
    15301 tctccgctca actgtatatt tgtacacaag gtattgtaat attcttctgc cttcttaatg
    15361 aactccagtt ttttttgtgc tatttctaat gtcggcatct ctctctccta tttcaactta
    15421 cccaagtttg gtacaactcc caaaagtgtc atctgcagtg cattttcgat atcttccgga
    15481 cgtttcacac gagtgtccaa aagttcaaga agaagaacta taacactagt tccaatcacc
    15541 cctgccaaaa aaccaattag tgtattgcgt ttaatatttg gcgaagacgg tgatatcgcc
    15601 ggtcttgcct cctccagtgt tgtcacatca gaaacacgag taatactgat aattttttga
    15661 gcagctactt ctcttaaaga gttagcgata cggcttgcct cttcaggaac tcgatcacta
    15721 actgaaacag agacaatacg ggtatcaact ggtactgtta ctttaatttt attagccaaa
    15781 ccttttggca tcaaatctag tttcaaatca gaaataactt cctccaaaac atcctgcgat
    15841 aggacaattt cacgatagtc tttaaccaag tatgctcctg cctgcaagtc ttgattggtt
    15901 aaaccaggct tctctccctg attacggtta actacataaa tccgagtcgt actagtaaac
    15961 tcaggtttga taacaaaagt actgtaggca aaagcaactg aagaagttat aattgccact
    16021 aataaaatga ccaactttct tttccataaa gctctgaata gttgcaatac atcgatttcc
    16081 aaagtgtttt gttccttcat attttctcct aaattaattg atccattata atttttctgg
    16141 gattatctac aaaaagttct ttcgcttttt tcgctccata tttcttagca atgatatcat
    16201 atgcctgttg catatatgga ggtctactgt ctaaattgtg catgtcactt gcaactacat
    16261 gaactaaatc acgttccaaa aaataccgag ctctcttttt catgaattta tatttttcac
    16321 caaagaactt aggttttgaa acatgataac tatttatctg agtatagcac cccatatcaa
    16381 tcagttcacg aacacgtttt tcgttattct ctaaagcatc ataacgttca atatgagcaa
    16441 ttactggcgt gattcccaac atcaaaatat tgctcaatcc cgtatgaatc tgacgatagg
    16501 aagtatgcat gctaaactca atcaaggcat aacgactatc attaagggta ggaatttctt
    16561 ttttttctag cttttctaga gcatccagag tatagtatat ctctgcgcca taagcaatga
    16621 ctaaatcatc tgctacttct tttgcaattt cccgaacctg aagaaagttt tctgctatct
    16681 tctcttccgg agtttcaaac atgcccttgc gacggtgaga ggtagagaca atggttctca
    16741 ccccctgcct gtaggattct gccaagagag ccttgctttc ctctcttgac ttgggaccat
    16801 catctacatc aaagacgatg tgcgaatgga tgtctatcat tttatctacc ctccatcaca
    16861 tcctgtatag ctgctttaac tacagttaaa ctactatcat ctatttccat cacatagagg
    16921 ttactgtctg gcattgcata agaaggaaga tccatccgac ctgtcccttt taaatcttga
    16981 gaatttactt tataattccc tccactttcc aactgagtat tcactaaatc tatcatagtc
    17041 tcaatcggta tatttgtttg aagagaatcc tgcaatcctt gaagaatact actatagttt
    17101 ttcaaaacct ctgtagaagt taacttctga ataattgcta caatgacctt ttgttggttg
    17161 cgaccacggt cacggtctcc atcggttagt gagtagcgtt cacgtacaaa acctaaagct
    17221 tgctcagagt ctagatggac attccctact gggaaatgga acttcccatg tagagctgaa
    17281 aactcttgat cattatgaac atctacccct cccaataagt caatcatttt caagaaagaa
    17341 gtgaagttca atcgcacata gtaattgata tccactccat agagattttc taaggtgtga
    17401 atggacgaat caactccata aatgcccgca tgggttaatt tatctttttg attatttcca
    17461 ctatctgcga ttggtacata ggcatcacgt ggcgttgtgg tcaagaggat tttcttggta
    17521 tctcgattga cagtcattag gatattgaca tctgatcgcg acaccgaact aataggacca
    17581 taggtgtcaa ttccactaac atagatattg aaagactgat tcttagacgt cttaggagcc
    17641 tctacttttt tagtgaatcc cttggtataa atctttttta tcttcgatgc gtagtctgga
    17701 tactctgact cgatgatatt ttcaaagaca ctatttagga caatggcctt agtctcccct
    17761 gcaatcaaac tcttgtaagc tgccaagtaa gacgaactct ggttgaccgt caaatcggta
    17821 ttctgacttg acttgatatc agctagtagt ttttgaatat tttcattatc agtcccagtc
    17881 ggtgctgtca cactcgtcag ttgcgtaaca ttttcgatct tactatctgc taaaacagcg
    17941 acactgattg aatattctga gtaattagaa gtcgcattta aacgattggt cagtccaaca
    18001 aactgctgta ctgcaaagag cgacactgag ctgacaagga tagagaacag caacagaaaa
    18061 atagtaaact tttcagcttt tttatagata atcaagagta gccctaccaa ggcaactagt
    18121 aggactaacg cagttaccac taggttaaga tatctaaaag caaggatatt gtacttaaag
    18181 attaagaaca ataaaaaaca aattaacaat aaataaatag tcagcaaaac gatattaaca
    18241 cttcgcttca ctttctgtga acgtgatttt ttaaaacgtc tactcatgat taacacctat
    18301 accttgaaca tcatacaatt atatcacttt tttacggtaa tgtctacacc tttattttca
    18361 ctatctgcat ctttaagtat cttagtagac ttcccgcgaa ccaaaaatat agtaaaatga
    18421 aataagaata ggacaaatca atcaggacag tcaaatcgat ttctaacaat gttttagaat
    18481 cagatgtgta ctattctagt ttcaatataa
//
LOCUS       DAVBOU010000042        18308 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBOU010000042 DAVBOU010000000
VERSION     DAVBOU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.042"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            166..480
                     /locus_tag="VQ879_001604"
                     /pseudo
     CDS             166..480
                     /locus_tag="VQ879_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            657..1316
                     /locus_tag="VQ879_001605"
     CDS             657..1316
                     /locus_tag="VQ879_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3143729.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1341..2408
                     /locus_tag="VQ879_001606"
     CDS             1341..2408
                     /locus_tag="VQ879_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3143730.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2511..3521
                     /locus_tag="VQ879_001607"
     CDS             2511..3521
                     /locus_tag="VQ879_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143731.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3533..5224
                     /locus_tag="VQ879_001608"
     CDS             3533..5224
                     /locus_tag="VQ879_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3143732.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5227..5937
                     /locus_tag="VQ879_001609"
     CDS             5227..5937
                     /locus_tag="VQ879_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3143733.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6033..6224
                     /locus_tag="VQ879_001610"
     CDS             6033..6224
                     /locus_tag="VQ879_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143734.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6509..7510
                     /locus_tag="VQ879_001611"
     CDS             6509..7510
                     /locus_tag="VQ879_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3143735.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8118..8192
                     /locus_tag="VQ879_001612"
                     /pseudo
     CDS             8118..8192
                     /locus_tag="VQ879_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8651..10012
                     /gene="trpE"
                     /locus_tag="VQ879_001613"
     CDS             8651..10012
                     /gene="trpE"
                     /locus_tag="VQ879_001613"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3143736.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10009..10575
                     /locus_tag="VQ879_001614"
     CDS             10009..10575
                     /locus_tag="VQ879_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3143737.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10586..11590
                     /gene="trpD"
                     /locus_tag="VQ879_001615"
     CDS             10586..11590
                     /gene="trpD"
                     /locus_tag="VQ879_001615"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3143738.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11587..12354
                     /gene="trpC"
                     /locus_tag="VQ879_001616"
     CDS             11587..12354
                     /gene="trpC"
                     /locus_tag="VQ879_001616"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3143739.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12341..12940
                     /locus_tag="VQ879_001617"
     CDS             12341..12940
                     /locus_tag="VQ879_001617"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3143740.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12918..14141
                     /gene="trpB"
                     /locus_tag="VQ879_001618"
     CDS             12918..14141
                     /gene="trpB"
                     /locus_tag="VQ879_001618"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3143741.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14134..14910
                     /locus_tag="VQ879_001619"
     CDS             14134..14910
                     /locus_tag="VQ879_001619"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3143742.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14882..14983)
                     /locus_tag="VQ879_001620"
                     /pseudo
     CDS             complement(14882..14983)
                     /locus_tag="VQ879_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15212..15352
                     /locus_tag="VQ879_001621"
     CDS             15212..15352
                     /locus_tag="VQ879_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143743.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15389..15943
                     /locus_tag="VQ879_001622"
     CDS             15389..15943
                     /locus_tag="VQ879_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143744.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15958..17109
                     /locus_tag="VQ879_001623"
     CDS             15958..17109
                     /locus_tag="VQ879_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3143745.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17161..17820)
                     /locus_tag="VQ879_001624"
     CDS             complement(17161..17820)
                     /locus_tag="VQ879_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3143746.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17890..>18308
                     /locus_tag="VQ879_001625"
     CDS             17890..>18308
                     /locus_tag="VQ879_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143747.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5903 a         2959 c         3937 g         5509 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttaataaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctag gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaatt
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatga ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat aaaaaaagtt tgacagcgct tgacaaagga aacggtttca
      601 ttgtataatg taaacatggt gacaccgatg tcaaatataa aaaagaaggt ctttatatga
      661 aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc tctgggaata
      721 cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat attattcaat
      781 cacgttatag agaattacca tttatcgata agtttacttt aactccaagg aattctattc
      841 acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta
      901 atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa
      961 tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga aaacaaaaca
     1021 tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg
     1081 tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc catatttcaa
     1141 ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag
     1201 cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact
     1261 atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt aaataaaata
     1321 ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg
     1381 gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt
     1441 catctgaaga aaaagctgat aaaagtcaag aattagtaat ctattcgaac tcagtctcaa
     1501 atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg
     1561 ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg
     1621 cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac
     1681 tagtacagta caagcctaaa tggttagata aaattgatca atctttatca gataaagata
     1741 attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct gatgtaaaag
     1801 aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat tcaatttatg
     1861 gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt taccttgatg
     1921 aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa tactttgcaa
     1981 atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc
     2041 caattcaata cggtatgatc tggggttctg gagcgttaat cggacaaaaa gaacaaaatg
     2101 ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa caaactatgg
     2161 ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg tttggtcaat
     2221 cagaaattca agtagaatat agtaaaaaat ttggctctat ccctgccaat aaagatgccc
     2281 taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca caaaatattg
     2341 actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg
     2401 tacaataaga aataagagtt attttttatg tccaagtctc tctattattt ctaaatttat
     2461 ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat
     2521 ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata
     2581 tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt
     2641 tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag
     2701 atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc
     2761 tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag
     2821 ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc
     2881 aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg
     2941 ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg
     3001 acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta
     3061 ttactacttt atatgttact catgatcaag aggaagcctt gactttatct gatagaattg
     3121 cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt
     3181 ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag
     3241 tccacgaagt attactgaaa aatacaagcg ttttcttaga agataaaaaa ggatacattc
     3301 gattagagaa agttcgattc aatcgtgaaa ctgaacaaga tttcattcta aaagggacaa
     3361 ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc
     3421 agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg
     3481 tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca
     3541 taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt
     3601 tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc
     3661 ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag
     3721 ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct
     3781 atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc
     3841 tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg
     3901 attgattaca aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg
     3961 gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt
     4021 aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc
     4081 aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc
     4141 acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg
     4201 tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc
     4261 tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac
     4321 tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc
     4381 tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata
     4441 tggattgttc acagttttca tgcttccact aatttttata gtattatact catttacaga
     4501 tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg
     4561 cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat
     4621 tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca
     4681 taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag
     4741 tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa
     4801 tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc
     4861 attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc
     4921 agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat
     4981 tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga
     5041 cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc
     5101 aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct
     5161 gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa
     5221 ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt
     5281 ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca
     5341 ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa
     5401 tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca agttatatca
     5461 ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt
     5521 ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt
     5581 ttttatgagg gagctctttt agtagctatt tctgtttggg gtgtgatatc catgttccaa
     5641 ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa
     5701 tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc
     5761 gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttcca
     5821 gataaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga
     5881 ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat
     5941 ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta
     6001 atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt
     6061 taggtaaaat agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt
     6121 tttatgatat ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa
     6181 atgttatctt taaagaaaaa attaactcta tgttaaaatg ttaaattgac aggctattat
     6241 atgtttttat aaatcctaca cattttactg aaaaagttaa tctacaattt tatggtagtt
     6301 ttttctcata tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga
     6361 aatgcaattt aaactttttt gaagggaaag aatatttgta aaattaattt tgtgaatttg
     6421 tggatcttaa ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat
     6481 attagaatgt tcgtaatgga ggactgaaat gaaaaatata aatgggaaaa aggtaactat
     6541 ttatgatatt gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg
     6601 tggagtaaat gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc
     6661 gtatattcca aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat
     6721 ttctgtaaaa aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt
     6781 gttacggacg tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga
     6841 tacaattagt aattcaatta tatcaagcac aggtagccta gtagatggtg ttattgtttt
     6901 ttatgaaagt gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct
     6961 tgttttcggt gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc
     7021 tacttatgat atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat
     7081 gggaggagaa tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga
     7141 taaaaattac tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta
     7201 ttcttatgca atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg
     7261 agatgaaaag gttcaaggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga
     7321 tgatatttct atcattggat ttgataatat tcctatttct cagtattata ctccagcttt
     7381 gtctacaatt gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc
     7441 aattattaaa ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca
     7501 gagtttctag tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa
     7561 taagttctgt ttagcctcca ttcagtttct attgagttgg atccaatttc taacgagtgg
     7621 gacatgttca tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa
     7681 atcgtaaaaa agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga
     7741 aaagtaacta tttttgatct tcagggagcc tgtggtgatt gtgaataggt ggttggaagt
     7801 agtgaaagtg ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc
     7861 ttacagtgca gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt
     7921 gaggtggcac cgcgttacca acgccctcac acggaagtat attctgtgtg tgggcttttt
     7981 tctatccgtc gtttgcttta tcttttatta gggccttaac tcgctttgat gaacttgagt
     8041 tctatctaca gctccttgcc tcctactaaa agtaaacaaa aaggctggac taatacgaaa
     8101 aaagctagta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
     8161 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat acctacgata
     8221 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta ccgagatgaa
     8281 catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat tgcagattac
     8341 tagaagctaa aaaataatag atggaaaaat tacagtcttt tctctcacag agagcttgtg
     8401 gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa
     8461 acatcattct caagggagtg ccctttatcg cacagcctgt tacaggaggt atctgagaca
     8521 ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc
     8581 aagttatttt gcgtggggat ttttcataca gtcgccacga actagaatta gaactgaaag
     8641 ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat
     8701 gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca aggaaacggc
     8761 tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa atggagttct
     8821 ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca
     8881 taagagtcag caccattcag agctcccttt tggtggtgga gccattggtt ttgtgggtta
     8941 cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc
     9001 agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat
     9061 acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg aaaaatcctt
     9121 gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggattt
     9181 atcaccactt gacttcaaac cgcatatcgc tccacataag tttgagggaa tggtagaaac
     9241 agctcgtgac ttgattcgta acggtgatat gttccaatgc gtactcagcc agcgcttctc
     9301 agcagaggtt actggaaatc catttgactt ctacagaaat ctccgcgtga ctaatccttc
     9361 taattacctt tatttctatg attttgggga ttatcaaatc atcggagcca gtccagaaag
     9421 tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag
     9481 aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga
     9541 aacagcagag catcgaatgt tagtagacct gggtcgtaat gatattggtc gcatctctga
     9601 aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca
     9661 tctgaccagc gtggtcaagg ggcgtttgct tccagaactc actgccatgg atgccttgaa
     9721 agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgtgcta tgagacgtat
     9781 ctatgaactg gaaacagaaa aacggggcgt atacgcagga gcaatcggct acttgtctgc
     9841 gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc
     9901 ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga
     9961 aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg
    10021 attgacaact atgattcttt tacctataac ttggcccaat acattgggaa ttttgcagaa
    10081 gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt
    10141 ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt
    10201 cgtgactttg caggcaagaa gccgattcta gggatttgtt taggccacca agccattgca
    10261 gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat
    10321 atcaactttg aagcgccatc tgttttgtat caaggtattg aggatgaccg tgcggtcatg
    10381 cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg
    10441 actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag
    10501 taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag
    10561 aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga
    10621 aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac
    10681 tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa cacctgaaga
    10741 acgcacagcc attgcccgag tcatgagagg acatgcccag catattccaa ctgagattca
    10801 tgatgctatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac
    10861 aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc
    10921 gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct
    10981 caaaccagct gaactaggta aggtctttga taaaactggc atcgtctttc tcttcgctaa
    11041 aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac
    11101 gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg
    11161 aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa
    11221 acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac
    11281 caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt
    11341 gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga
    11401 aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa
    11461 tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt
    11521 ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta
    11581 ccaaaaatga gtcaggaatt tttagcacga atcttggagc agaaggcgcg tgaggtggag
    11641 cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg
    11701 aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg
    11761 ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga
    11821 gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta
    11881 cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat catagatgaa
    11941 aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgcttat tgtggcagcc
    12001 ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg tctggaagtc
    12061 ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg tgctgagatt
    12121 atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac cagtgtagat
    12181 ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat tttcacaggg
    12241 caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac agctcttatg
    12301 caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaaaatttg
    12361 tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg actatatcgg
    12421 ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg tgttggcaaa
    12481 gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact
    12541 gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga
    12601 tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg
    12661 gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg
    12721 ccagcccttt gattggggtc aactggatac gactggacta gcacagccct tctttatcgc
    12781 aggtggcctt aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt
    12841 agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt
    12901 tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat
    12961 tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct
    13021 accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt
    13081 acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag
    13141 ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg
    13201 ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg
    13261 gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta
    13321 ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgtatggagc
    13381 ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag gatgcggtca
    13441 atgcagccct tcgttcatgg gtagctaata tcgatgatac ccactatatc cttggttctg
    13501 ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag
    13561 aggctaaaca acagtaccgc gatatgacag gtcaagatct gccagatgcc ctagtagcct
    13621 gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag
    13681 tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta
    13741 ccttgaccaa gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg
    13801 cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat cctggtattg
    13861 gtccagaaca ttctcactac cacgatatca aacgtgccag ctatgtccct gtgacagatg
    13921 aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc ccagccttgg
    13981 aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt
    14041 ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct
    14101 tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg
    14161 aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc tggtgaccac
    14221 gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct
    14281 gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa
    14341 gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa
    14401 accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac
    14461 ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca
    14521 gacttgcctc atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc
    14581 ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggc
    14641 gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac
    14701 cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg
    14761 acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt
    14821 gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt
    14881 atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca
    14941 cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc tagttttata gtgaattgaa
    15001 tctggaatat tacactacgg ttcctaaaat attttaagaa agtgatttga atttcccaat
    15061 aaatttgttc agtttttaat tgattttact atagaagata taattttcta aattactctg
    15121 acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa atgatataat
    15181 tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct ttgattcgct
    15241 tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg tagatgaacg
    15301 tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgt gacctaatca
    15361 tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat tagcaggaca
    15421 gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat
    15481 tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa ataagagtgg
    15541 ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt cttcctacaa
    15601 aaatgatgaa gatagtcatt cctttccaat tcagatggag ttagtttctg atgaaatgat
    15661 tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga ttttaactta
    15721 tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg atgcacgaac
    15781 tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt cgtaccattt
    15841 cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa cagaagattt
    15901 tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag tatgtaaatg
    15961 tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag agcagaatta
    16021 gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa
    16081 cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt aacttatttt
    16141 gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag aaatgcagac
    16201 ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt agatagtttg
    16261 attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga cctaagtaat
    16321 gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct ttatgccagg
    16381 gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga acgttcaggc
    16441 atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc atggtcaaaa
    16501 ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg aaattttgac
    16561 ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa tgaagatggc
    16621 gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc aaaagaagag
    16681 tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga tagttatatt
    16741 ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc ttttaagtta
    16801 ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca aaaaggttac
    16861 aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt
    16921 attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat gtctaaacaa
    16981 agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag
    17041 tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta caaaagaaat
    17101 aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa ttggacttta
    17161 tcaaacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga ggaaaggcac
    17221 gaaaggaagt ctttcctttt tcttttgcag gagaaaggct aggatacccg tcgcagaagc
    17281 aaactgaatc aagatcagta actccgttat gctaaagacg agagcacaag aagctaaaaa
    17341 gaggaaatcc cctgcgccca tgcggatatc gataaaatga gccaaaattc caagagcaag
    17401 gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt ggaaagtcat
    17461 ccagaccagt aagggatatt cctgatggcg aaagtcatag atgctcaagg tcaaaccagc
    17521 ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca gaaagaggag
    17581 tcctaagcct agttcaaaga gggcatacca gacaggatag cggaccttgc agtagcgaca
    17641 gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac gcaagggagt
    17701 ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa aacggtcaat
    17761 gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa aatcaatcat
    17821 acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag ataagatggt
    17881 gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc tcaatttgta
    17941 tgccaatggt ccaactccct aggcaaatcc tttcaagaac aatggatggg atcaaggatt
    18001 ccttttctac tgacccttca agccttggaa gaagtctttt caatctttga tgaacaagag
    18061 tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat cgggagattt
    18121 tttatcaacc cccagaaaca ggggcaaggc ttaggtagcc aggctttaag gaaatttgtt
    18181 agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt cgaggcaaat
    18241 caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat ggttgaagca
    18301 cctgtacg
//
LOCUS       DAVBOU010000043        18177 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBOU010000043 DAVBOU010000000
VERSION     DAVBOU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.043"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ879_001626"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ879_001626"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3143748.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYRTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ879_001627"
     CDS             complement(863..2125)
                     /locus_tag="VQ879_001627"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3143749.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ879_001628"
     CDS             complement(2135..3265)
                     /locus_tag="VQ879_001628"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3143750.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ879_001629"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ879_001629"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3143751.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ879_001630"
     CDS             complement(5231..6118)
                     /locus_tag="VQ879_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3143752.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ879_001631"
     CDS             complement(6108..6569)
                     /locus_tag="VQ879_001631"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3143753.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ879_001632"
     CDS             complement(6566..7474)
                     /locus_tag="VQ879_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3143754.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ879_001633"
     CDS             7467..7664
                     /locus_tag="VQ879_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143755.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ879_001634"
     CDS             complement(7716..8387)
                     /locus_tag="VQ879_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3143756.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ879_001635"
     CDS             complement(8441..8662)
                     /locus_tag="VQ879_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3143757.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ879_001636"
     CDS             8934..9743
                     /locus_tag="VQ879_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3143758.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ879_001637"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ879_001637"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3143759.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ879_001638"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ879_001638"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3143760.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ879_001639"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ879_001639"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3143761.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ879_001640"
     CDS             complement(13018..14277)
                     /locus_tag="VQ879_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3143762.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ879_001641"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ879_001641"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3143763.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ879_001642"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ879_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ879_001643"
     CDS             complement(16071..17546)
                     /locus_tag="VQ879_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3143764.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         5332 a         4169 c         3324 g         5352 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtccggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcataaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctga
//
LOCUS       DAVBOU010000044        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBOU010000044 DAVBOU010000000
VERSION     DAVBOU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.044"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ879_001644"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ879_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3143765.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ879_001645"
     CDS             complement(881..1867)
                     /locus_tag="VQ879_001645"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3143766.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ879_001646"
     CDS             complement(1830..2630)
                     /locus_tag="VQ879_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3143767.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ879_001647"
     CDS             complement(2880..3260)
                     /locus_tag="VQ879_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3143768.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ879_001648"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ879_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3143769.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALSDAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ879_001649"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ879_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3143770.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ879_001650"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ879_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3143771.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ879_001651"
     CDS             complement(4805..5989)
                     /locus_tag="VQ879_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143772.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ879_001652"
     CDS             complement(5993..6580)
                     /locus_tag="VQ879_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143773.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ879_001653"
     CDS             complement(6613..6801)
                     /locus_tag="VQ879_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143774.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ879_001654"
     CDS             complement(6980..9220)
                     /locus_tag="VQ879_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3143775.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ879_001655"
     CDS             complement(9204..9854)
                     /locus_tag="VQ879_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3143776.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ879_001656"
     CDS             complement(9922..10491)
                     /locus_tag="VQ879_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143777.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ879_001657"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ879_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ879_001658"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ879_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ879_001659"
     CDS             complement(12409..12909)
                     /locus_tag="VQ879_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143778.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ879_001660"
     CDS             complement(13089..14057)
                     /locus_tag="VQ879_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3143779.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ879_001661"
     CDS             complement(14143..14358)
                     /locus_tag="VQ879_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3143780.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ879_001662"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ879_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3143781.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ879_001663"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ879_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3143782.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ879_001664"
     CDS             complement(15847..16584)
                     /locus_tag="VQ879_001664"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3143783.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ879_001665"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ879_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3143784.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5189 a         4134 c         3375 g         5440 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctga aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatatta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgatac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBOU010000045        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBOU010000045 DAVBOU010000000
VERSION     DAVBOU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.045"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ879_001666"
     CDS             3..308
                     /locus_tag="VQ879_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3143785.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ879_001667"
     CDS             356..1831
                     /locus_tag="VQ879_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3143786.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1854..1931
                     /locus_tag="VQ879_001668"
                     /pseudo
     CDS             1854..1931
                     /locus_tag="VQ879_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2091..8792
                     /locus_tag="VQ879_001669"
     CDS             2091..8792
                     /locus_tag="VQ879_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3143787.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ879_001670"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ879_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ879_001671"
     CDS             complement(10107..10466)
                     /locus_tag="VQ879_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3143788.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ879_001672"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ879_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ879_001673"
     CDS             11498..12055
                     /locus_tag="VQ879_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3143789.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ879_001674"
     CDS             12048..12302
                     /locus_tag="VQ879_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143790.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ879_001675"
     CDS             12314..14368
                     /locus_tag="VQ879_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3143791.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ879_001676"
     CDS             14547..15407
                     /locus_tag="VQ879_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3143792.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ879_001677"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ879_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3143793.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ879_001678"
     CDS             16356..16922
                     /locus_tag="VQ879_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3143794.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ879_001679"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ879_001679"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3143795.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5445 a         3450 c         3979 g         5227 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaaacctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagcaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBOU010000046        17890 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBOU010000046 DAVBOU010000000
VERSION     DAVBOU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17890
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.046"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..775
                     /locus_tag="VQ879_001680"
                     /pseudo
     CDS             1..775
                     /locus_tag="VQ879_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1091..2065)
                     /gene="pta"
                     /locus_tag="VQ879_001681"
     CDS             complement(1091..2065)
                     /gene="pta"
                     /locus_tag="VQ879_001681"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3143796.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(2109..3005)
                     /locus_tag="VQ879_001682"
     CDS             complement(2109..3005)
                     /locus_tag="VQ879_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3143797.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(3002..3820)
                     /locus_tag="VQ879_001683"
     CDS             complement(3002..3820)
                     /locus_tag="VQ879_001683"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3143798.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(3804..4475)
                     /locus_tag="VQ879_001684"
     CDS             complement(3804..4475)
                     /locus_tag="VQ879_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3143799.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            4603..5172
                     /locus_tag="VQ879_001685"
     CDS             4603..5172
                     /locus_tag="VQ879_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3143800.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            5285..6244
                     /locus_tag="VQ879_001686"
     CDS             5285..6244
                     /locus_tag="VQ879_001686"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3143801.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            6254..7369
                     /locus_tag="VQ879_001687"
     CDS             6254..7369
                     /locus_tag="VQ879_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3143802.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            7374..7721
                     /locus_tag="VQ879_001688"
     CDS             7374..7721
                     /locus_tag="VQ879_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3143803.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            7729..7944
                     /locus_tag="VQ879_001689"
     CDS             7729..7944
                     /locus_tag="VQ879_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3143804.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            8027..8668
                     /locus_tag="VQ879_001690"
     CDS             8027..8668
                     /locus_tag="VQ879_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3143805.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            8686..9375
                     /locus_tag="VQ879_001691"
     CDS             8686..9375
                     /locus_tag="VQ879_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3143806.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9372..10052)
                     /gene="radC"
                     /locus_tag="VQ879_001692"
     CDS             complement(9372..10052)
                     /gene="radC"
                     /locus_tag="VQ879_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3143807.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(10095..12386)
                     /gene="pcrA"
                     /locus_tag="VQ879_001693"
     CDS             complement(10095..12386)
                     /gene="pcrA"
                     /locus_tag="VQ879_001693"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3143808.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(12577..13382)
                     /locus_tag="VQ879_001694"
     CDS             complement(join(12577..13005,13008..13382))
                     /locus_tag="VQ879_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3143809.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(13762..14622)
                     /locus_tag="VQ879_001695"
     CDS             complement(13762..14622)
                     /locus_tag="VQ879_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3143810.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(14638..15915)
                     /locus_tag="VQ879_001696"
     CDS             complement(14638..15915)
                     /locus_tag="VQ879_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3143811.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(15908..16459)
                     /locus_tag="VQ879_001697"
     CDS             complement(15908..16459)
                     /locus_tag="VQ879_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143812.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(16475..17734)
                     /locus_tag="VQ879_001698"
     CDS             complement(16475..17734)
                     /locus_tag="VQ879_001698"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3143813.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         5432 a         3902 c         3262 g         5294 t
ORIGIN      
        1 atccctcgta tcatcaacca aaagattgct caaaagttaa ttgaaaagat ttctatgact
       61 gatattgccc atcagctttc catctcaact tcaactgtta ttcgtaagct caatgatttt
      121 cactttgagc atgatttttc gcgtcttcct gagattatgt cttgggacgt tgaaacagtc
      181 cggggagtga ctgtttcaat cgggagatgg agatgagctt tattgctcag gactttgata
      241 agctcaatat cataactgtt cttgagagca gaacacaagc catcatccga aatcccatga
      301 atacaaggct atcaagcgct actggaaact cattcaacag gatagccgta aactgagtga
      361 taagcgattt tatcgtccta cttttcgtat gcatttaacc aataaagaga ttttagacaa
      421 gcttttgagc tattcacaag acttgaaaca tcactatcag ctctatcaac tcttgctgtt
      481 tcactttcag aataaggaac cggagaaatt tttcggactc attgaggaca atctaaagca
      541 ggttcatcct ctttttcaga ctgtctttaa aacctttcta aaggacaaag agaaaatcgt
      601 caacgccctt caactaccct attcaaacgc caaattggaa gcgaccaata atctcatcaa
      661 acttatcaag cgcaatgcct ttggttttcg gaactttgaa aacttcaaaa aacggatttt
      721 taccgctctg aatatcaaaa aagaaaggac aaaatttgtc ctttctcgag cttagctttt
      781 cttcaaccca ctacagttga caaagagcca gaaaacgcat aatagcaggt gtcaagacac
      841 ttaatattat gcgttttctc atgaaaaaat tctcttttca tactcattta aaatcaaaaa
      901 gggaaattat cgttttacgg acatacatat tacagatttc tataggtcgt gtatagacag
      961 gatatcatcg cttggaagtt ttcctttttg acaccaatca gtaatttagt tctcaggaat
     1021 taatggcagt gcttttcgta catagtttca taactacagt atagcatagt atatcgcttt
     1081 atagttttca ctattgatga actgcttgag ctgctgtgat gagggtcaac ttgtaaacat
     1141 catctgcatt acatccacga gaaagatcat taactggctt gtttaaacct tgcaaaacag
     1201 gtcctacagc cgcaaagcca cccaggcgtt cagccatctt gtaaccgata tttccggcct
     1261 cgatacctgg gaagatgaag acatttgctt gaccagctac cgtacttcca ggagctttca
     1321 gagctgcagt ttcaggaaca aaggctgcat caaattgcaa ctcaccatcg atttcaaggt
     1381 caggacgcaa gtcgtgagca attttagttg cttcaacgac cttatcaacg ctttcaccaa
     1441 accctgaacc tttagtagaa tagctcaaca tggcaatttt aggttcgatg ccaaacatct
     1501 tagctgtgat tgctgagttg atggcaattt cagccaaggc ttctgcatct ggattgatgt
     1561 taatggcaca gtctccaaat aggtaacgtt ccgtaccacg aaccatgagg aaggctcctg
     1621 aagtacgagt tacatttgga cgagttttga tgatttgtag agctggacga actgttgaag
     1681 ctgttgagtg aatcgctcct gacaccattc catcaaccaa gcccaagtaa accaacatca
     1741 caccaaagta gttgacatct tcaaccaaaa ccttgcgtac atcttcttca gtcattttgc
     1801 ccttgcgacg ctccaccaag gcagaaacca tttcttcaaa ttgaggataa tgttgagggt
     1861 cgatgacctc ataaccatcc atgattcctt caatttcaag ataaatttta attttttcag
     1921 gatttccaag caaaacagga atcacttctg tttcttttac taagcgtttt gttgcttgaa
     1981 gaatacgagg ctcttcccct tcagggagaa cgatacgagc atttttacca acaaggttgg
     2041 ctttgagact ttcaaaaact tccatgagtt ttctccttta agataataat tatactctga
     2101 gacagttttt atagagtatt agttgataac tgggtaataa ggttactgaa atcatccggc
     2161 aagggacttt ctaactgcaa gtcttgctct aaaaatggat gataaaagga taggtaatgg
     2221 caatgcagag cctgacgttg aataccatct tccagactac caccatacaa atcatctccc
     2281 agcaaaggaa aaccgatatg agaaaaatgg actcggattt gatgggttcg accagtgtgc
     2341 aggtgaatat agaccaagtg aatatttcca taagaagcta caatcttgta tgaagtatgg
     2401 gcatactttc cgcctttagc cactcgtctg gtaataatgg aatcttcatc acgcgcaatc
     2461 ggagcaataa tttccccttc tggctccaaa tgtccatctc ccttaaccaa agcaaagtag
     2521 cgtttctcga tagatttctt ctgcaactgc ttgtctaatc gtgcatgggc ataaccgtgc
     2581 ttggcaaaga gcatcaagcc agaagtgtcc ctatctagtc tggtaacaat gtgaacctgc
     2641 tgattttcat aattttgctt gacatagtaa cccttgataa aattggcaat ggtgttagag
     2701 tgattgacac taggaataga agccactcca tagggtttat tcaagactag aaagtggtca
     2761 tcctcataga gaatatctaa tggatgctca atagcctcca aggtttcaaa gccttcctca
     2821 gcgggaatgt aaatggtaac gtagtctcca acgtccaata gatacgttgc attttgcggt
     2881 tgattattga ccagaatagc tccacctcga aacttaatct tagccagcaa tcccttagaa
     2941 acctcgtgct tttttaaaaa ggtcttaacc ttgacatgtt catctgcgat aaattcaaac
     3001 ctcattcatc cacctcaccg ataaaggcat ccttaacacg gttccagaaa ctggtatggc
     3061 taggagtcgc gacaaagtga atcttatgat ggtcgatttg atactcaata cgctcaatat
     3121 tacggaaaga ataaacgcta ttgtcaaccg aaatagtatg ataatcgttt cttgttggaa
     3181 taagttcaat cttatccttc ttaggcacaa taatggaaga gcccagtgtt cgataaacac
     3241 gattattaag gctggcaatt tccgttaatt gcaaagcttc aatggtaggg tgtaaaacag
     3301 caccgccaag agacttgtta taggcagtac taccagtcgg tgtcgaaact gttagcccgt
     3361 ctccacgaaa acgttcaaag ggaacaccat ttattacaat atctgccacc atggttcgat
     3421 cagacctgcg gatgctggct tcgttgagtg ctctgaaaat cttaacttca ccattttcaa
     3481 gaaagacctt cacattcaga acagggtaag aaacccttgc cccagtatct agctgcaaat
     3541 tagtcactag cttgtccaac tcaaaatcac gataatctgt atagaagccc aaatgtccag
     3601 tatgaagacc gataaagcgg accttgtcaa gctgattttc gtacttatga aaggccgaca
     3661 agagcatacc atccccgcca atggaaatga caatatccgg attggtatca ttgagtataa
     3721 actgatttct cttcaaacga tctcgcaatt catacaaaac cctttgactc tgcggttttc
     3781 tattggctat cagatcaatt cgtttacctg tattcttcat ctgtatcgtc actgtttcct
     3841 acaccgtcat ttaattttct actcaaagga tcaaaaagtg cctgggcttc ttggatatca
     3901 tcacgaattt cacccatttc ttcatccaac tgatgggcga ttctagctgt aatttccagt
     3961 cgcttcttaa tctcatctgg gaaatcccct tggtacttgt agttgagaga atgttctatc
     4021 gttgcccaga aattcatggc caaagtacga atttgaattt ctgccaaaat agtcttagct
     4081 ccattgatgg tatcaaccgt atattctact accacatgat aggaacgata gcctgatgct
     4141 tttctatgag taatgtaatc tcgctcctgt atgattcgca tatcctgacg cttgtgcaaa
     4201 atatccacta cttccttgac gtcatctaca aactgaacca tcacacgtaa gccagcaata
     4261 tcctgcaaat cgtgttccaa ggtcgcataa gtaatgccac gacgagccat tttttctttg
     4321 atgctctcaa ttggcttgac tcgaccggtc acaaactcaa ttggagaatg cttattttgc
     4381 ttacgatatt gcttacgaat accacgaagt ttaatcttta actcaccaac agcttgaatg
     4441 taaggatcta gaaattcttc ccattctaag gtcatatatt ctcccttgtt ctcatattat
     4501 ccgtcaaaaa tatctttgat tttttctcca gattcatata caataaatac aatgcttatt
     4561 ataccataaa tccgctttca acgataaaaa aaggtaagaa aaatgaaaca tttagaaatt
     4621 gaattgaaaa cactattgaa aaaagatgaa tacaatcgtc taaaagacca gttcacaggt
     4681 gtcactcctg ttcttcaaac aaattactac atcgacacgc ctgattttga actgcgagaa
     4741 aagaaagtcg ctatgcgcat tcgaaccttt gaagactggg ctgagttgac actcaaagtc
     4801 ccgcagagtg ttggaaacat ggaatacaac caaaaattgc aactaaaaga tgctgaggac
     4861 tatctgagta aggaagaact tcctcaagga ctagtactgg atgaattggc gaaacatggt
     4921 atccaaagta agaactggca ggttcttggt tgtctaacaa cgcttcgcta tgaaatgaaa
     4981 acagctattg gtctcatggc actggatcag agccgatact ttgatataac agattacgaa
     5041 ttggagcttg aagtggaaaa tcatgagcaa ggcaaacagg atttccgaca atttttagag
     5101 aaaaatcaga tttcctacca aaaagctcct tcaaaattgg ttcgatttgt caaaagtatg
     5161 aaaaatagct gaaataatct ccattttttg gtaaaataga aaagataaaa atacacaaat
     5221 cccagttcat atatgtaagg taaatataac taggatttat aaagtttaca gaggacggtc
     5281 tataatgtca gatagaaaaa acatgaaact tttcgcactc aactctaacc aagagattgc
     5341 acaaaaaatt gcccaagctg ttggtgtccc acttggaaaa ctatcatcac gtcaattttc
     5401 agacggagaa atccaagtaa atatcgaaga aagtgtccgt ggttatgatg tttacatcat
     5461 ccaatcaaca agtttccctg tcaacaacca cctaatggaa ttgttaatca tggtcgatgc
     5521 ttgtgtgcgt gcaagtgccc acagtatcaa cgttgtcctt ccatattttg gctatgcacg
     5581 tcaagaccgc attgcttgtc ctcgtgagcc acttacagca aaactagttg ccaatatgct
     5641 ggttaaggct ggagttgatc gtatcctgac tcttgatttg catgccgttc aggttcaagg
     5701 tttctttgat attccagtgg ataatctttt cactgttccc ctattcgcaa aacattactg
     5761 cgataaagga ttgcttggtt cagatgttgt tgtcgttagc cctaaaaatt caggtgtcaa
     5821 acgtgcgcgt agcctggctg aatatcttga tgctcctatc gccattatcg actaccctca
     5881 agacgatgca actcgtaacg aaggttatat tattggtgat gttgaaggta agaaagctat
     5941 cttgattgat gatattttaa atacaggacg taccttctct gaagcttcta aaatcgttga
     6001 acgtgaagga gctacagaaa tttatgctgt ttctagccac ggtctcttcg tcgagggagc
     6061 tgctgagctt cttgacaata ctaatattaa agaaattctt gtgactgatt cagtagcaac
     6121 aaaagaaaaa actcctaaaa atgtatgcta tatcactgct agtgagttaa ttggtgatgc
     6181 tatcgtacgt attcacgaaa gaaaaccagt cagcccactc tttgcctaca ataaaaagaa
     6241 ataaggtgat tctttgattt atttggacaa tgctgcaacg actcctatgt cagcagttgc
     6301 tatttcagct atgaccaagg ttatgcaaga aacccacgga aatccttcta gtattcatgg
     6361 tcatggtcgt caagctggca aactcttgcg agaagcccgt caggaactag cccagttact
     6421 aaggacaaaa cctcaacata tctttttcac ttctggtggg actgaaggca ataatactac
     6481 catcattggc tactgtcttc gtcaccaaga acaaggaaaa catatcatca caactgccat
     6541 cgagcaccat gctgtccttg aaacaattga ttacttggtt caacactttg ggtttgaagc
     6601 aaccattatc cagccagaaa atcaagaaat cacagcccag caaattcaaa aggctttacg
     6661 tgacgatacg attttggttt ctaccatgtt taccaataat gagacaggaa acctactgcc
     6721 catcgctgaa attggccaaa tactcaagca acaccctgct gcctatcatg ttgatgcagt
     6781 tcaggctatt ggtaaaatcc caattcattc agaagaattg ggcattgatt ttctcactgc
     6841 ttctgcccac aaattccatg gtcctaaggg aatcggtttt ctctacgcat ctagcatgga
     6901 ctttgattcc tatctacatg gcggagacca ggaacagaaa aaacgtgcag gaactgaaaa
     6961 tctgcctgct atcgtaggca tggttgcagc cctaaaagaa gacctagaaa aacaagaaga
     7021 acattttcaa catgtacaaa atctagaaac tgcctttctg gcagagctgg agggcattca
     7081 gtattacttg aatagaggaa aacatcatct cccttatgtt ctcaatattg gatttcctgg
     7141 tcagaaaaat gacctcttac tccttcggct agatttagct ggaatttcaa tctctactgg
     7201 ctcagcctgt actgcaggcg ttgtccaatc cagccatgtt cttgaagcca tgtatggcgc
     7261 aaattcagaa cgcttgaagg aatcccttcg catcagtttg tcgccacaaa ataccgttga
     7321 agacctacaa accctcgcaa aaaccttaaa agaaattatc ggaggttagc catatggcat
     7381 ttgaaaaaat cattcagtta aaaaattgtc gttacgatta cactcttagc ccttctgtta
     7441 aaaaattcac cctcaaagat aacacctttt ttgaaactaa ggttggtaac tatgaactga
     7501 ctcgcctttt ggaaaaagtg ccaaacagcg gtgaaggctt ccaactcaaa atcatcatta
     7561 acaaggaagt tacaggggct aaaatcaata tcactgataa gtttggcctt cgtctagttg
     7621 atattttcaa atcagaagac caccatattc atcaggaaaa attctacttc ctcatggata
     7681 gcttggtaga acgtggtgtc tttacaaaat cggaaagata gagccaaaat gtttgaactg
     7741 acctataagg actgctatca tgtagagcgt actctcaagt atgaggatca tgaggctctc
     7801 atgttgactt tgtcaggatg tgtaacctta ccagatacac tttatgtgac ttctctgact
     7861 tttaggggcc aaaaagttta tcagggtctg gtcggagacc tctaccgttt tctatctcat
     7921 gcagattttt tacatcaaaa ctaagatttt tcttagtttt ttcttatttt tgttgatttt
     7981 ttcacaatgt ttctataaaa tagaagaata gaaaggttgt gattttgtga aagataaaca
     8041 gtttgctatt ccaaaagcta cagcaaaaag actctctctc tactatcgaa tttttaagag
     8101 atttcatgca gaaaagattg aacgtgccaa ctctaagcaa attgcagagg ctatcggtat
     8161 tgattcagcg accgtacgtc gtgatttttc ctattttggt gaacttggtc gtcgtggttt
     8221 tggatatgat gtcaaaaaac taatgacatt ttttgccgat ttgctcaatg acaactctat
     8281 taccaatgtc atgctggttg gtattggaaa tatgggccat gcccttctcc actaccgctt
     8341 ccacgaacgt aacaagatga agattatcat ggcctttgac ctagatgacc atcctgaagt
     8401 cggtacccaa actcctgacg ggattcccat ttacggaatt tctcagatca aggataaaat
     8461 caaggatgct gatgtgaaga ctgctatcct aactgttccc agcgtcaagt cacaagaggt
     8521 tgctaatctc ttggttgatg ctggtgtgaa aggaattctc agtttttcac cagtccatct
     8581 gcatttacca aaagacgtgg tcgttcagta tgtcgatttg acaagtgaac tccaaaccct
     8641 cctctacttc atgcgaaaag aggattagaa agcgaaaatc attttatgaa aaaaccagtt
     8701 attgggatta caggaaacga aaaaactcat ccagatgatg acatcatgat gagctacgca
     8761 gcaaaaggct ttgttgaagg cgttaaagat gctggaggga ttcccatcat cctaccgatt
     8821 ggtgatcaag aaatggcctg ccactatatc agtttgattg acaagctcat cttgacaggt
     8881 gggcaaaatg tcgatccaaa attctatggc gaacccaaaa ccattgatag cgatgactat
     8941 caccttcaaa gagatatctt cgaactggcc ctcatcaagg aagctattaa acagaaaaag
     9001 cccattttct ctgtctgccg tggtacccaa ctctttaacg ttgccatggg tggaactttg
     9061 taccaagata tcgaagacca ttggcaggat tcttctgttg agtacacaac tcaacgcttg
     9121 gtgacagaac cagataccgt tctccaagaa atctatggag aaatctctca tatcaactcc
     9181 ttccaccacc agagcatcaa ggacttagca ccaaatttaa aagttgtggc tcatgatcct
     9241 aaagatggta tcattgaggc tgtcatgagt acggatgatg tcgcctttct cggtgtccaa
     9301 tggcatccag aacttctttt tgaaaatcgt cccaaagata aaaaactctt tgactatgtc
     9361 gttaatgaac tttagattaa atctgtcttt tcacgataac taaagtaatt agaatgagag
     9421 acaatcaaat ggtccaagag aacaatcccc atcagttcgc aggcttcttt aacaagttta
     9481 gtgacatgat catcattttg gctaggcgct accgctcctg aaggatgatt gtggaccaag
     9541 ataagagaag tcgccatatg cttgattgca tagtgcagaa tctctcgcgg ttcagcgata
     9601 ctacgagtta cagaaccgat aaaaatggtc tgctgatgga tgatttgatt ttgagtattg
     9661 agatagagtg ccaccaggtg ctcttgtttt ttatccccta attcctgctg catcttcttg
     9721 gccaactttt gactgctgag aatactttcc atttcaagag tctcgtgttt gtgaatacga
     9781 tgccccagtt caatcatagc ttgtaattct atggccttaa cacgcccaat accagacaaa
     9841 ctctgcaatt cctgcagggt catttttttc aaatccgtta ggcttgaaag attgttcaag
     9901 actttttggg caatttcaaa aacgctagct tgacgtgttc ctgtcctgag taaaatagct
     9961 agcaactctt ggttactaag cgcttcaact ccttccttgg ccagcctttc tcttggtaat
    10021 agtgaatctt cttggaatga aatactgtac ataaaaatcc tcctcacttt attattcgtg
    10081 agaaggatgg aaaattagat ttttttctca attggagcca cactggctaa aagttttttc
    10141 aaacctactt ctgggaaatt gattttcaat tcctgcctag caccgctacc tgaaacttcc
    10201 agaacagttc cctctcccca tttcttgtgg agagcaatgt caccaatgga ccaatttgcc
    10261 tcgctagatg ctgattttgc gccagctgta aattgaccaa atggaagacc gcttgactgg
    10321 attgattttg gggcagcacc gcgtttacgg tcttgaagag cctgagccaa actcatacct
    10381 tgaccaaagg aaatactacc actgctatat gatgccttaa agcttgtatt tgcaggacga
    10441 gccagacctt gatactcaag caagtctgaa ctgatttcgt taataaaacg agtcggacgg
    10501 ttataattgg tacgaccaaa aagcaagcgt gagttggcat tggtcagata gagaattttc
    10561 tctgcacgcg tgatacctac ataggctaga cggcgctctt cttctaattc atctgtatct
    10621 tcagtcgcac gactaagtgg aaagacattt tcttccatcc caatcaaaaa gacaactgga
    10681 aattcgagac ctttggcagc atgcagggtc atcaaggtca cttctgatgt ctcctgacta
    10741 cctgaatctg tgtcggcaat caaagccaag tcatttaaga aacgactcag tttgtccaga
    10801 ccagtttcct cttctgtcac atcagtggtg tcatcaaagt tcttcgtaac agaaagaaac
    10861 tcttcgatat tttcaacccg tgccttgctt tctagagtcg cttgggcgtt aagaatatcg
    10921 acataacctg ttttttctag gacggactca accaactctg taatgcttaa gtggtctagc
    10981 tgctcccgca aatcaagcat catattggca aaatcccaga tagattgggc tgccttaccc
    11041 ttgataccag acaacataat attagcagaa gcatccagca tagacatatt ttgcaaattt
    11101 gcaaaatcac ggattttctc aactgtacct ggaccaattc cacgtttagg ctcgttgata
    11161 atacgctcaa aactaatatt gtcactcaaa ttagcaataa ggttgagata agcaataata
    11221 tcgcgaattt ccttacggct gtagaatttg gttccgccaa ccatggtata aggaatgtta
    11281 gacttgagca gggcttcctc aattgtacgg gactgggcat tagtccgata gagaactgca
    11341 aaatccttat gaaggaagtt ttgactgcga ctaagttcat cgatggttct ggctacaaat
    11401 acagcctcat ccagctcatc atcggcacga tagtaaacga tttgctcccc atcagcgttt
    11461 tgagtccaga gatttttagg acggcgattt ttattgtttt taataacctc gttggccgct
    11521 tggagaatgg ttttggttga gcggtaattt tcctccaaca aaacaacctt ggctttgggg
    11581 taatcctttt caaagtccaa gatattctgc atatcagcac cacgccaacc gtagatagac
    11641 tggtccgcat ccccaaccac acagatattt ttaaaacggg aagccaagag tttgaccaat
    11701 tggtactgag cgtggttggt atcttggtac tcatcaacgt ggatgtattg gaatttttgc
    11761 tggtagtagg ttaaaacatc aggattttga tcaaagagac gcaaggtcag cataatcaaa
    11821 tcatcaaagt caacggattc agactgacga agttcttttt gataggctgt ataacactgg
    11881 gccacaattt gcgtatacat atcgccagct tgggcagcat aagcaacatc atcaatcaaa
    11941 tcattcttag cattggaaat ggtccccaaa atagttcgtt cattccattt tttaggatcc
    12001 aagttcaact gtttgagaat acgtttcatg agcgttcgct gttcaccagg atccacaatt
    12061 gtaaaattac gattgtagcc aatatggtcc gcatcgcgac gcaaaatacg cacacacatg
    12121 gagtggaagg tcgcaatcag acagttctga gtagctggat tgagactata agcacgctct
    12181 ttcatctcac gcgcagcctt gttggtaaag gtaatggcca agatattcca aggattgacc
    12241 agcttttcat caatcaaata agcgatacgg tgggttaaaa cacgagtctt tccagaacca
    12301 gcccctgcca tgattagcaa gggaccttct gtcgtttgca ccgcctcagc ctgacggtca
    12361 ttcattccat ttaataatgc gttcatcttc tcttccttac tcttgaagtc aatatttcta
    12421 ttatatcaga aatcagggaa aatagaaact ttacggggag tagcaaaata tagtggattg
    12481 aaactagaat actacactgt gggtttctaa aacactcgac ttttcaccca attttttcat
    12541 aaactagctc aatacctcaa tagacttcct gcaaaactag aatcctagtt catgattgat
    12601 aataccagca ataaaattca ttcgtaatcc gaagcgttta cgatgatttc gataagttgt
    12661 tgaaaacatt ttaaacgttt ttactttggc aaagatgttc tcaaccttgc ttctctcctt
    12721 agatagcgca tggttataag ccttatcttc aactgttagc ggcttgagtt tgctggattt
    12781 acgtggagtt tgtgcttgag gatatatttt catgagccct tgataaccac tgtcagccaa
    12841 gattttacca gcttgtccga tatttctgcg actcattttg aacaacttca tatcatgaca
    12901 atagttcaca gtgatatcca aagaaacaat tcttccttga cttgtgacaa tcgcttgagc
    12961 cttcatagcg tgaaatttct ttttaccaga ataattggct agttgatttt tttagggcga
    13021 ttggttttta cttccgtcgc atcaatcatt accgtgtcct cagaactgag aggagttctt
    13081 gaaatcgtaa aaccactttg aacaagagtt acttcaaccc attggctccg acggattaag
    13141 ttgctttcgt gaataccaag atcagccgca atttgttcat aagttcgata ttctcgcaca
    13201 tattgaagag tggccataag aaggtcttct aggcttaatt taggttttct tccacctttt
    13261 gcatgtttaa gttgataagc tgtttttaat acagctaaca tctcttcaaa agtggtacgc
    13321 tgaacatcaa caagacgctt aaatcgtgca tcagttagtt gtttacttgc ttcatcattc
    13381 atagaactac tataccatgt tttgtttcgc aggaagtata atataaaaaa ataaatttaa
    13441 gattggcaat acgaacgtta aacagaattc catttctctt tttagaatca aaacgacaat
    13501 attgtggaat ctctacagga acaatagact gcgacactaa aatatcctcc cttagtttta
    13561 ctttactaat agtatatagg aggagagccc tgaatcctag accctttgtt atgatgcgct
    13621 tacaaacaga gttggaaaaa atcttaaaag cagaaaaacg catgatatca gcccctaaca
    13681 cttgatacaa tgcgttttat tatgaaaaga tctactggat tttttatcaa aataaacttc
    13741 cagtagtctt ttcacttttt attaataagt tccttcttca ccttggctag tcaagataac
    13801 aggtccatct ttcgtaatga caaattggtg ttcatactga catgacaatc caccgtcaat
    13861 ggtcttatgc gcccaaccag ttttcatatc tgtatcaatt tcccaatcgc ctgtattgat
    13921 cattggttca atggttaaga ccattccttc acgaagacgg agtccacgac ctgcaatacc
    13981 atagttagga accattggtt cttcgtgcat agttgggcca acaccatgac caaccaaatc
    14041 acgcactaca ccgtaaccac gactttcagc gtattcttga atagccgcac cgatatcacc
    14101 gatacgattt ccaacaacag cttgctcaat acccttgtac atagcttctt tggttacatc
    14161 catcaagttt ttgacttctt cggacggtgt accaacagca taagcccaac atgagtctgc
    14221 taaaccacca gaatagctct gagtatattt tttcatttgt tcaacattgt tgaagtttaa
    14281 ttttgagaca ttcaggtcag atttagcaat gggacctccc aaaaccatat caactttgag
    14341 caaatcacca tctttcaaga tataatgacg agggaaagcg tgagccactt catcgttaag
    14401 agagcaacag gtagcataag gatagtccat catggcaccg tcaaccccaa tctgaagtgg
    14461 aaggaaattt tcttctttac aacgacggcg gacatattct tcaacttccc acatatctac
    14521 gcctggctta atcaaatcac gtaagcctat atgaatactt gctagaaaat caccagcctt
    14581 gtccatagct tcgatttcac gagctgattt taatgttatc atcttttctc ctagtttcta
    14641 attaatttta acagtcacat ttgcttttga aacaatctgg tgaccatgat aaatatcgta
    14701 atcaattata gctgaccgtc tcgtatgatg aataatccgt gcctgaatgc gcaatatatc
    14761 atctatctga acagcctgca aaaagtagat cagcatctgc tcgataatga gattgcgacc
    14821 actattaaca actaaatctt gggtcatgtg ggtcagaatt tctgccaata caccattagc
    14881 caaaactcca tttttttcta gcataaaggg ttccactgta atgactactt catcatggtg
    14941 ataagagagc ttttgtccaa tctgctcaga aaaagttggt agagccgaaa cttgggaacg
    15001 gctcatcttc tccatgacat ctcgtcgcgt cacaacgcca agcaaagttt gattgcttcg
    15061 aacaactggt accatttcaa agtcttctgc gatcatccgt tgactcacat tggcaatatt
    15121 tgtcgataat ccaaccaaaa atagactacg agacataacc ttatcaattg tcgtgcttgg
    15181 tgatttatca ccagcgtctc tcatggttac aacgccaaca acgacctgat gttgattgat
    15241 aacagggaaa cggctgctac gattcttacg aaccaagtcc aaataatctt taactgtatc
    15301 tgtctctctc agaaaaccat actcatgact agggcgataa agtttctcaa ctgtcagaat
    15361 atcagtcttg atttggacat ttgacaaggc tttattgatc atggtcgcga cggtaaaggt
    15421 atcatgctta cttcttagaa caggaatccc tttttgattg gccagtttaa gcacatcatc
    15481 atgaacctga aatccccctg taaccagaac tgcattttca ttttccaagg ctagcaactg
    15541 aatacgggtt cggtctccga caatcaagag ccccccatca tgaaggtaag acaagatatt
    15601 ttgttcagtc atggcaccaa ttgaaaactt actaaattct ctctctaaac cttcttgccc
    15661 agccagaacc tcagaagaag tcacttctgc aatttcagca aacgttaatc tctctatagc
    15721 aactttctgg gatttaacac gaattgttcc acttctagga cgggtctcca caattccacg
    15781 gttttcagct tctttaatag cccgataggc tgttccatca ctaactccta gatgattcga
    15841 aatgctacga acactgaccc ttttacctac tggtaattcc tccaaatagc ttagaatttc
    15901 ctgatgctta ctcattgaac tctcctttta cataccgaaa ttcaagataa tcccgcattt
    15961 ttcttgtgta acgatcactt cccttaaact gacggaacaa actaaatcca gacttaagag
    16021 caactctttg gctagcttca ttttcaaggt gggtaatgat agataattgt tttaagccaa
    16081 attcctcaaa agaaagctga caaatttttc taacaacctc tgtcataaat ccttgcgacc
    16141 aagcatcttt tctcaaaaaa tagccaagct cagcttcttt tttgatttca tctaacttct
    16201 caaatttaat agaaccaatc atttgttgat ttttctggtc acaaattgcc cacactccca
    16261 aaggggactt cataaagtaa ttggccagtg catattgact ttcttccaga cttgcctgcg
    16321 ttgggaaaat aaattgaaga ttttctggat ttgaagctat ctcgcggaag tcctgactat
    16381 cactaaaaaa gaaaggacgc aaatacaagc gatccgtttc aaaaaaagaa aacattgcta
    16441 atttggtcca aatattcata aacacctcta cggtttaatc ctcaacaagt ctaatatccg
    16501 ctcctaaatt acgtaatttt tcgataatat cagaataacc acgtaagata aactcgatat
    16561 tggtaatttc agttttacct tcagccataa gcccagcaat gactagtgca gccccagctc
    16621 ttaagtcggt cgctttaaca ctggccccac gtaaatcacg tccacccgtg tacaaaatat
    16681 gaccatttgt tgtcgaaata tccgcatcca tctttgctag ttcaaaaaca tgatttacac
    16741 gtttttcgta aatcgtatcg acaattgtac cacgaccatt cgctcttagt aaaagagggg
    16801 taagcggttg ttgcaaatca gttgcaaagc ctgggtaagg agctgtctta atattgattg
    16861 ctttcaaatt agactgttcc tcgacaaaaa tgctgtcttc agatacagtc attctcactc
    16921 ccatttcttc caacttagca ataaaccctt ccaggtgttc gtaaagaaca ttatttatac
    16981 gaattccttt accaactgca gcagctaaag atatatatgt tccagcttca atgcggtctg
    17041 gaatcacctg atgacgtgtc ccatgtaatc tttcaacacc atcaataatg atgatattag
    17101 ttcctgcccc acggatatgg gcacccatat tattcaagag agtagctaca tcaataatct
    17161 caggttcacg ggctgcattt tcaataatag tacgaccatt tgctttaacc gcagcaatca
    17221 tcgtattaat cgttgctccc acactaaccg tatccatgta aatacttgca ccatgaagtc
    17281 ctgtatcttt agcagataac ttcatgttat ctccctcgta gctagcagtg gcacccatag
    17341 cttcaaacgc cttaaggtgt aagtcaatcg gacgaggacc aagatcacat cctcccggta
    17401 gaccaactgt cgcttcacca aaacggccta agaggctccc ataaaaatag taagatgcac
    17461 gaagactgtt aattttacca taaggcattg gaatattttg aacacctctt ggatcaatct
    17521 ccaagacatc gtcataacgc ttaacagtag ctcccatcaa ttccatgatt tcgacaagac
    17581 tggctacatc cgaaatatct ggaacacaat ccaaagtcac cacatcatca gccaagataa
    17641 tagctggaat taaggccaca acactatttt tagcaccact aatagtaatt tcaccttgca
    17701 gtggtaatcc accattgata acaatttttc tcattctaag ttttcaatac tctttcaaga
    17761 tttctaataa ggtcttcaaa ataaagtata tcataaattt atcctttttt ccatcctttt
    17821 caattttatt ggataaatca gagttgacga gttagtaact gaattactaa tactcaataa
    17881 aaatcaaaga
//
LOCUS       DAVBOU010000047        16747 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBOU010000047 DAVBOU010000000
VERSION     DAVBOU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.047"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            74..538
                     /locus_tag="VQ879_001699"
     CDS             74..538
                     /locus_tag="VQ879_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3143814.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            696..1121
                     /gene="lacA"
                     /locus_tag="VQ879_001700"
     CDS             696..1121
                     /gene="lacA"
                     /locus_tag="VQ879_001700"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3143815.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1152..1667
                     /gene="lacB"
                     /locus_tag="VQ879_001701"
     CDS             1152..1667
                     /gene="lacB"
                     /locus_tag="VQ879_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3143816.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1678..2607
                     /locus_tag="VQ879_001702"
     CDS             1678..2607
                     /locus_tag="VQ879_001702"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3143817.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2609..3589
                     /gene="lacD"
                     /locus_tag="VQ879_001703"
     CDS             2609..3589
                     /gene="lacD"
                     /locus_tag="VQ879_001703"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3143818.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3823..4659
                     /locus_tag="VQ879_001704"
     CDS             3823..4659
                     /locus_tag="VQ879_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3143819.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4695..5012
                     /locus_tag="VQ879_001705"
     CDS             4695..5012
                     /locus_tag="VQ879_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3143820.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5012..6703
                     /locus_tag="VQ879_001706"
     CDS             5012..6703
                     /locus_tag="VQ879_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3143821.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            6918..8324
                     /gene="lacG"
                     /locus_tag="VQ879_001707"
     CDS             6918..8324
                     /gene="lacG"
                     /locus_tag="VQ879_001707"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3143822.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8414..8626
                     /locus_tag="VQ879_001708"
     CDS             8414..8626
                     /locus_tag="VQ879_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3143823.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(8905..9666)
                     /locus_tag="VQ879_001709"
     CDS             complement(8905..9666)
                     /locus_tag="VQ879_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3143824.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9848..10810)
                     /gene="nrdF"
                     /locus_tag="VQ879_001710"
     CDS             complement(9848..10810)
                     /gene="nrdF"
                     /locus_tag="VQ879_001710"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3143825.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10998..13157)
                     /gene="nrdE"
                     /locus_tag="VQ879_001711"
     CDS             complement(10998..13157)
                     /gene="nrdE"
                     /locus_tag="VQ879_001711"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3143826.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13238..13456)
                     /gene="nrdH"
                     /locus_tag="VQ879_001712"
     CDS             complement(13238..13456)
                     /gene="nrdH"
                     /locus_tag="VQ879_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3143827.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13807..14070
                     /locus_tag="VQ879_001713"
     CDS             13807..14070
                     /locus_tag="VQ879_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3143828.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14076..15809
                     /gene="ptsP"
                     /locus_tag="VQ879_001714"
     CDS             14076..15809
                     /gene="ptsP"
                     /locus_tag="VQ879_001714"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3143829.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16064..>16747
                     /gene="phtA"
                     /locus_tag="VQ879_001715"
     CDS             16064..>16747
                     /gene="phtA"
                     /locus_tag="VQ879_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3143830.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5214 a         3020 c         3475 g         5038 t
ORIGIN      
        1 tatcaatcat gaactaggat tctagttttg caggaagtct aataaagaaa ctagcaaggt
       61 caggccttac tttattggtg gacatccagg atttaattgt cttctacttg atgatgaagt
      121 ctatgaagat tattatctag agtttgagaa agaagagatt tgctctgttc cacgtccttt
      181 cccagaaaca ggtatgttgg atttccaaga tagaagtcca tggctagagg gacaaaaaga
      241 aatagatctt agttatgatc ttttcagcac agatgcagtg actttggatg aattgcaatc
      301 tcgaacaatt gcccttcgtt ctcttaaaca tgataaggga ttgaaagtgc attttgcaga
      361 atttccaaac ctcatcatct ggtcaacttt gaacaaggga cctttcatta cctttgaacc
      421 atggtctggc ttgtcaacat tccttgaaga aggagatcat ttagaagata agaagaatgt
      481 ttgtctctta gaagccaatc aggttgaaga attagggttt gagatagaag ttttataaaa
      541 aaagtaaaaa ataaataaca aaaacaaaca caaactgttg acttcttcaa acaatagtag
      601 tatattatgt ttgtgaggac taattgactg ttttttaaag acagccaata cactgctgga
      661 atccagcata gaaaaaataa aaaggagtat acaatatgtc tattgttatc ggtgcagatg
      721 ctgcaggttt gagattgaaa gaagttgtga aagacttctt agaaaaagaa aacttccacc
      781 ttgtggatgt tacagctgaa ggtcaagact ttgttgatgt gactctcgct gttgctgcag
      841 aagtaaacaa agaagaacaa aaccttggta tcgtgattga tgcttatgga gctggtccat
      901 ttatggttgc aactaagatc aaaggaatgg ttgctgcaga agtatctgac gaacgttcag
      961 cttatatgac tcgtggccac aacaactcac gtatgatcac tatgggggca caacttgttg
     1021 gtgatgaatt ggctaaaaac atcgctaaag gatttgttaa tggtaaatac gacggtggtc
     1081 gtcaccaaat ccgggttgac atgttgaaca aaatgtgcta attagattat agtaagaaag
     1141 gtaagttaaa aatgagaatt gcaattggat gtgaccacat cgtaacagat gaaaaaatgg
     1201 cggtttcaga atttttgaaa tcaaaaggat atgaagtcat tgactttggt acctatgacc
     1261 atacacgtac tcactaccca atctttggta aaaaagtagg ggaagcagta actagtggtc
     1321 aagctgatct cggggtatgt atctgtggta ctggtgttgg tatcaacaac gctgtaaata
     1381 aagttccagg tgttcgttct gccttggttc gtgatatgac aacagccctt tatgctaaag
     1441 aacaattgaa cgccaacgtt atcggttttg gtggtaagat tactggtgaa ttgcttatgt
     1501 gtgatatcat cgaagctttc attcatgctg aatacaaacc atctgaagaa aacaaaaaat
     1561 tgattgcgaa aattgaacac cttgaaagtc acaatgctca acaaacagac gcaaacttct
     1621 tcactgaatt ccttgaaaaa tgggatcgtg gagaatacca cgactaagag gtaacctatg
     1681 attttaacag ttacaatgaa cccatccatt gatatttcct atcccttgga tgagttgaag
     1741 attgatactg tcaatcgtgt ggtggatgta accaaaacgg ctggtggtaa gggactcaat
     1801 gttacccgag tactttcaga atttggcgat tctgttcttg ctactggttt agtgggtggc
     1861 aaacttggtg agtttttggt tgaacatatc gataatcaag taaagaaaga tttcttctca
     1921 attcagggag aaactcgtaa ctgtatcgct attctccacg gagacaacca aacagaagtt
     1981 cttgaaaaag gtcctgaagt attggaacag gaaggtcaag actttttgga acatttcaaa
     2041 aaactcttgg agtcagttga agtagtggcc atctcaggta gtctgccagc tggccttcca
     2101 gttgattact gtgcgagctt ggtagaactt gctaatcaag ctggcaagcc tgtagtcttg
     2161 gactgctcag gtgcagcact tcaggctgtt cttgaatcac cccataaacc aacagtcatc
     2221 aaaccaaata atgaagaatt gtctcagctt cttggaagag aagtttctga ggatttggat
     2281 gaattaaaag aagtacttca agaacctttg tttgcaggga ttgaatggat tatcgtttca
     2341 cttggtgcca acggtacttt taccaaacat ggtgacactt tctacaaggt agatattcct
     2401 agaattcagg cggtaaatcc tgttggatct ggagactcta ctgtggcagg aatttcttca
     2461 ggacttcttc acaaagaatc ggatgcagaa ttactcatca aggcaaatgt ccttggtatg
     2521 ctcaatgctc aagaaaaaat gactggtcat gtcaacatgg ccaactatca agctctatat
     2581 gatcaattaa tagtaaaaga ggtataaaat ggctttaaca gaacaaaaac gtgtacgctt
     2641 agaaaaactt tctgatgaaa atggtatcat ctcagctctt gcatttgacc aacgtggtgc
     2701 tttgaaacgc ctcatggctc aacaccaaac agaagaacca actgtggccc aaatggaaga
     2761 acttaaagtt ttggtagcag atgaattgac taaatacgct tcatctatgc ttcttgaccc
     2821 tgagtatgga cttccagcaa ctaaagctct tgatgaaaaa gctggtcttc tccttgctta
     2881 tgaaaaaaca ggttatgaca caacaagcac aaaacgcttg ccagactgct tggatgtttg
     2941 gtctgcaaaa cgtattaaag aagaaggtgc agatgcagtt aaattcttgc tttactatga
     3001 tgtagatagc tcagacgaac tcaatcaaga aaaacaagcc tacatcgaac gcatcggttc
     3061 tgagtgtgtg gctgaagata tcccattctt ccttgaaatc cttgcttacg atgaaaaaat
     3121 tgcagacgca ggttctgtag aatacgctaa agtaaaacca cacaaagtta tcggtgctat
     3181 gaaagtcttt tcagacccac gctttaacat tgatgtcttg aaagttgaag ttcctgttaa
     3241 cattaaatat gttgaaggct tcgctgaggg tgaagtggtt tacacacgtg aagaagcagc
     3301 agccttcttc aaagcgcaag atgaagcaac gaacttgcca tacatctact tgagtgctgg
     3361 tgtatcagct aaactcttcc aagatactct tgtatttgct catgaatcag gtgcaaactt
     3421 taacggagtt ctttgtggcc gtgctacatg ggcagggtca gttgaagctt acatcaaaga
     3481 tggtgaagca gcagctcgcg aatggcttcg cacaactgga tttgaaaaca ttgatgagct
     3541 caataaagtt cttcaaacaa cagcgacttc atggaaagaa cgtgtgtaag aaagtcctcc
     3601 tagtttagga acatgaatct aaaaaaattt aaaaaaagtt gtatgtaaag gtttacaaaa
     3661 taacttactt gtgctatact taaatcacaa gttaatacaa ggtgagtgtt actaagtaat
     3721 attaggcatg atcacaggtg aattagaaat cagctgattt tctagttcat ttgtggtcat
     3781 tttttgtact catatacctt taaaatataa aaggaggttg acatgtatcg aattctaaat
     3841 ccaatgaatc acaatgtctc gcttgtcaga aatgataagg gagaagaggt gattgtaatt
     3901 ggtaagggga ttgcattcgg aaagaagaag ggggatttga ttgctgaaaa tcaggttgag
     3961 aaaatctttc ggatgaagac cgaagagtcc agagaaaact ttatggctct tctcaaagat
     4021 gttccgcttg attttatcac agtgacctat gaaattattg ataagctatc aaagaaatat
     4081 cattatccga ttcaagagta tctctatgta accttgacag atcatattta ctgttcttat
     4141 caagctctaa ctcaaggaag gtacaaggat agtaatctgc cagatatttc cgctaagtat
     4201 cctgtcgctt ttcaaatcgc aaatgaagct tttgaaattt accgtcagaa gctagcagat
     4261 cattttcctg aggacgaaat tattcggatt gcttatcatt tcattaatgc tgaaggtgaa
     4321 aatgaagtgg aacttgtgga gtcgattgat aagaggaaag aaattctcag gaatgttgaa
     4381 gaagttttaa cggactatgc aattcaacga actaaaaaga ataaccattt ctatgatcgc
     4441 tttatgatcc atttgaatta tttcttggat tatttagaca gatctagaga tgataaccaa
     4501 tcacttctgg atatggaaga tcatattaaa caatcctatc caaaagcctt cgagattggt
     4561 tccaagatct atgatgtgat tacgcaacat acgggtcttg atttgtataa aagtgaacga
     4621 gtttatctag ttctacatat ccaacgttta ttgtcataaa aatttattta aaactatata
     4681 aggagaattc tatcatgaat agagaagaag taacattgtt aggttttgaa atcgtagcct
     4741 atgctggcga tgctcgttca aaactattgg aagccttgaa ggctgctgaa gctggtgatt
     4801 ttgaaaaagc ggacgctctg gtagaggaag ctggtagctg tattgcagag gctcaccacg
     4861 cgcaaacaag tctattgact aaggaagctt ctggtgagga cttagcgtat agtgtgacca
     4921 tgatgcatgg tcaagatcac ttgatgacaa ctatcttgtt aaaagaccta atgcaccatt
     4981 taattgaact ttacaagaga ggagttaaat aatgaataaa ctaattgcat ttatcgagaa
     5041 aggaaagcct ttctttgaaa aactatctcg taatatctat cttcgtgcta ttcgtgatgg
     5101 tttcattgca ggtatgcctg ttattctctt ctcaagtatc tttatcttga ttgcctttgt
     5161 accaaactca tggggcttta aatggtctga tgaagttgta gcctttctga tgaaacctta
     5221 tagctattct atgggtattc tggctctctt ggtagctggt acaacagcta agtcattgac
     5281 tgactcagta aaccggagca tggaaaaaac caatcaaatc aactatatgt caacattgtt
     5341 ggcagcaatt gttggtttgt tgatgttggc agctgatcct atcgaaagtg gtctagctac
     5401 tggattcttg ggaacaaaag gtttgctttc agccttcctt gctgccttcg ttactgtagc
     5461 catctataag gtctgtgtta agaacaacgt cactattcgt atgcctgacg aagttccacc
     5521 aaatatctca caagtcttta aagatgtgat tccattcact ctatcagtgg tttctcttta
     5581 tgctcttgat ttactagctc gtcattttgt tggttctagt gtggcagaat caatcggtaa
     5641 attcttcgca ccactcttct cagcagcaga cggatacctt ggtattacca ttatctttgg
     5701 tgcctttgcc ttcttctggt ttgttgggat tcatggtcca tctatcgttg aacctgctat
     5761 cgcagcgatt acctatgcaa atgctgaagt caacttgaac cttctccaac aagggatgca
     5821 tgcagacaag attcttactt ctggtacaca aatgtttatc gttaccatgg gtggtacagg
     5881 tgcgacattg gtcgttccat ttatgttcat gtggttgaca aaatcgaaac gtaaccgtgc
     5941 aatcggacgt gcttcagtag ttcctacctt cttcggtgta aatgaaccaa tcttgtttgg
     6001 tgcacctctt gttttgaatc caatcttctt cattccattt atctttgctc caattgcaaa
     6061 cgtatggatt ttcaaattct ttattgaaac tcttggaatg aactcattca ctgctaatct
     6121 accatggaca actccagctc cactaggtct agttcttgga actaacttcc aagtgctatc
     6181 attcattctt gctgcccttc taattgtggt tgacgtagtt atttattacc cattccttaa
     6241 agtctatgat gaacaaattc ttgaagaaga acgttcaggt aagtctaatg atgaattgaa
     6301 agaaaaagtt gctgcaaact tcaacactgc aaaagcggat gctattcttg aaaaagcggg
     6361 tgtcgatgca gcacaaaata ccatcactga agaaacaaat gtcctcgttc tctgtgctgg
     6421 tggaggtaca agtggactcc ttgcaaatgc tttgaataag gcagcagcag aatacaatgt
     6481 ccctgtgaaa gcagcagcag gcggctatgg tgctcaccgt gaaatgttgc cagagtttga
     6541 tttggttatc cttgctcctc aagttgcttc aaactttgaa gatatgaagg cagaaacaga
     6601 taagctcggt attaaacttg ctaagacaga aggcgctcaa tacatcaaat taactcgtga
     6661 tggaaaaggt gccctagcat tcgtacaaga gcaattcgat taaggctagg aactgtgaaa
     6721 cagtctccca tcgttacgga aatcgctatg gcgaatttcc taatcgcctt attaattcgt
     6781 cggtaaaaag atatcgtttt tacctcctca tgtcacaatt cagtgacttg gtacaagaag
     6841 tgagatggag aagcatggct cactgactcc tctcctctca cttttacttt atttaaatca
     6901 agaaataggt gaaaaaaatg acaaaaacac ttccaaaaga ctttattttc ggtggcgcaa
     6961 cagctgctta tcaagcagaa ggtgctacac atactgatgg aaaaggacca gttgcttggg
     7021 ataaatatct tgaggataac tactggtaca ctgccgaacc agctagtgat ttttacaatc
     7081 gatatccagt tgacctcaag ctagcagaag agtatggtgt caatggtatt cgaatttcta
     7141 ttgcctggtc acgtattttc ccgactggtt acggccaagt aaatgttaaa ggtgttgagt
     7201 tttatcataa tttatttgca gagtgtcaca aacgtcatgt tgagcccttt gtaactcttc
     7261 atcactttga cacgccagaa gctctccatt caaatggaga cttcttaaac cgtgaaaata
     7321 tcgaacattt tgtagactac gctgccttct gttttgaaga atttccagaa gtaaactatt
     7381 ggacaacctt taatgaaatt ggaccaatcg gtgatggtca atatttggtt gggaaattcc
     7441 ctccaggtat ccagtacgac cttgccaaag tctttcaatc acaccacaat atgatggtgt
     7501 ctcatgcgcg tgcagtcaag ctatataaag ataaaggcta taaaggggaa attggtgttg
     7561 ttcacgctct gccaaccaag tatcctttgg atcctaaaaa tccagcagat gttcgtgcag
     7621 ctgagttgga agatatcatc cacaataaat tcatcttaga cgcaacttat ctaggtcgct
     7681 attcagctga aaccatggaa ggtgtcaacc atatcttatc agtcaatggt ggtagtttgg
     7741 atcttcgtga agaagatttt acaacattag aagctgcaaa agacttgaat gatttcctag
     7801 gaatcaacta ctatatgagt gactggatgg aagcctttga tggagaaact gaaattatcc
     7861 ataatggtaa aggtgaaaaa ggaagctcta agtatcaaat caaaggtgtt ggtcgtcgtg
     7921 tagctcctga ctatgtacca cgcacggatt gggattggat tatctaccct caaggtttgt
     7981 atgaccaaat catacgtgtg aagaaagatt atcctaacta caagaagatt tacatcactg
     8041 aaaatggtct cggctataaa gatgagttcg ttgataacac tgtttacgat gatggtcgta
     8101 ttgattacgt gaaacaacac ttggagatct tgtctgatgc gattgcagat ggagctaatg
     8161 taaaaggtta cttcatttgg tcattaatgg atgtcttctc atggtcaaac ggttatgaaa
     8221 aacgttacgg tctcttctac gtagattttg aaactcaaga acgttatcct aagaaatcag
     8281 ctcactggta taagaaagta gcggaaactc agattataga ctagtagaat tagtcattag
     8341 atatagaatt ttagtgagtc aaaaagatgt tcaaagattt tatccaatct atttatgaaa
     8401 aaaagtttat attataaatt tcgaaaaatg ctctcaaata ccgtgtttga cgagtgaaga
     8461 attgaaaagt cttggaaaat ggtatgtctc gactggtaaa gaatggattt gtcattcaga
     8521 tgatgagctg gaagaattta aaaatctatt tttaaatttt atcaatcctg aagaatggga
     8581 tactatctcc tttgattcag attttatgcc gtttcaacaa tcgtaaccaa tttctcaaaa
     8641 aagttaaatc ttatatttag tactctgtaa aactcttatc taatcacgtt gcttatactc
     8701 aatgaaaatc aaagagcaac tttaaactag gaagcgagtc gcagatttct caatgcatag
     8761 ctttgaggaa ttgggcaaaa agtctttgat atagaaaaac gcatagtatc aggtgtttca
     8821 acacctgata ttatgcgttt tattgtggga agatttactt tttttcttct gaaattgagt
     8881 tgttacccag gctctttcag tttattaagg cttgatgact ttaatgtgtt tagatagctt
     8941 aaaaaggatt gaatcactta gtttagaatc tgaaacaata gtatcaagat ttgatacatt
     9001 ataaaaagta taaaaatcaa acttattgaa cttgctatga tctgcgagta aatatttttt
     9061 attagaatta tttaaagcga tgcgttgagc ctctccctct tcctcgctaa aagtagctag
     9121 agctccgttt tgaataccat tacagctaac gaaagcttta gaaaattgga gattagagag
     9181 attttgtagg gtcaatgtac caacaaaagc acctgtaata tcgcgataat ttccacctat
     9241 taaaatcaaa tctgttaatt ttcgttcgct taaaatcaga aaaacaggta gactgttggt
     9301 tacgacgcgg atattgtcaa taggcaactc acgcgcaaaa aactctaatg ttgttcctgg
     9361 tccaatgaaa atagtttctc tttcttctac tagactgcct gcaaaatggg ctatttcttg
     9421 tttttctgcc gtttggaggg cttgtttttc aatatttgat cgctcattag tcaaaaggga
     9481 gttggttcga agtttttcag ctccaccatg cacacgaatc agcaaatctt tatcagctaa
     9541 ttcctgtaaa tagcgccttg cagtcatatc tgaaacggct atttcgtcca taatctgttt
     9601 aactgttatg gttcctttac tatttactat ctctaaaatt ttggttaatt tttcttgttt
     9661 gagcatatta tcacctcgtt tcctactact atcttaccat aaacaaactc atcattcaaa
     9721 tacaaaaaca acaaaatgaa acaaaaacaa aaatatcgaa gtttgttttc aaaactttcg
     9781 atatttttgt tgggttataa ctttgatgtt tctagtttac tttttgatga ttgagagtga
     9841 tggagaatta gtctaaaccg tagttatagt catcgtcttg catggcttca acttcgccaa
     9901 gaaggtaacc atttccgact tgagagaaga agtcatggtt ggaagttcct gttgaaatac
     9961 cgttcataac gattgggttg acatcttcag ctgaatctgg gaaaagtgga tcttgtccca
    10021 tgttcatgag agctttattg gcattgtagc gaaggaaggt tttaacctct tcagtccaac
    10081 caacaccgtc ataaagactc tctgtgtagc cttcttcatt ttcataaaga gtatagagta
    10141 ggtcgtacat ccattctttg agtttttctt gctcttcttc aggcaattca ttgaaaccaa
    10201 gttggaattt gtaaccaatg taggttccgt gaacagactc gtcacgaata atcaatttaa
    10261 tgatttctgc aacgttggct agtttgttgt taccgagata gtagagggga gtgaagaaac
    10321 cagagtagaa gaggaaggtt tcgaggaaga cgctggcaac tttcttttca agtgggctgc
    10381 cgtttaggta gatttcgttg acaatctcag ccttcttttg taggtaagga ttggtattgg
    10441 tccattcgaa aatttcttca atctcagcct tagtattcaa ggtagaaaag attgatgagt
    10501 aagatttagc gtggacagat tccataaatt ggatgttatt gaaaacagct tcctcatgtg
    10561 gtgtacggat gtctgcgcga agggcttgaa ccccagtttc agattgcata gtgtcaagaa
    10621 gggttaaacc accaaaaact tttccgacca agtctttctc tttgttagat agctttctcc
    10681 agtcatccaa gtcgtttgat aagggaatac gtgtatcgag ccaaaattgc tccgtcagtt
    10741 tttcccaagt tgatttgtcg atgacatctt cgatggcatt ccagttaatg gctttgtagt
    10801 aagtttccat ttaaaatctc tttctgtgtt tagtattgcg aactcacaat tatttctact
    10861 ttaccataat tctataggag tatcgcacaa aaagtcggaa gcccgacttt taaaatgtta
    10921 cataaattat gttatgacat agtagatttg attttatcag tgctgcttag ggaaaaataa
    10981 tgtttctatg ctagaaacta aatcacacag ctttcacatt ggttggcgcc gacttctcca
    11041 ccgtcatctg taaaggtacg gacgtagtag atagacttga ttcccttgtt aaaggcatag
    11101 ttacgaagga tggacaaatc acgtgtcgtt tgtttatttt ccctcttcca ttcgtaaagg
    11161 ccttttggaa tgtcactgcg catgaagagg gtgagtgaaa gtccttgatc cacgtgttca
    11221 gtcgcagcag cgtaaacatc gatgacttta cgcatatcca tatcgtaggc agaagtgtag
    11281 taaggaatgg tttctgtaga caagccagca gcagggtagt agattttacc aattttcttc
    11341 tcttggcgtt cttcgatacg ttgcgtaatc gggtggatag aagcagaaac gtcgttgata
    11401 tagctgatag aaccatttgg cgctacagca aggcgatttt ggtggtaaag accatcttct
    11461 tgaaccttgt cgcgaagttc agcccaatca gcaacaccag ggataaaaac atttttgaag
    11521 agttctttaa cacggtctga tgttggaaca aattcaccag ttacatactt gtcaaagtaa
    11581 cttccgttag catagtctga tttttcaaag ttgtggaagg taataccacg ttcacgcgca
    11641 atattgtttg actctaccaa ggtccagtag ttcataagca taaagtagat gcttgtaaat
    11701 tcaacagact caggtgaacc atattcaatg agttgttggg caaggtagct gtgcagtccc
    11761 atggcaccga gaccaaaggt gtgggcttgg ctatttccat ggtcaatcgt tggtacagct
    11821 acgatatgtg aactatctgt aacgaaagta agggcacgaa ccatagcacg gatagaacga
    11881 ccaaaatcag gtgaagtcat catgttaacc acgttggttg aacccagatt acatgaaaca
    11941 tctgttccca tttgaaggaa ttcttgagca tcgttgatca agcttggttc ttgaacttga
    12001 agaatctcag aacacaagtt actcatgata atctttccat caacaggatt tgcacggtta
    12061 gccgtatcga tgttgactac ataaggatag ccagactctt gttgcaattt agagatttca
    12121 gtttccaaat cccgcgcctt gatttttgtc ttgcgaatat ttggatttgc gaccaattca
    12181 tcgtattttt cagtaatgtc gatgtaattg aatggcacac cgtattcttt ttctacagag
    12241 taagggctga agaggtacat ttcttcattt ttacgagcca attcgtagaa tttatcaggt
    12301 actacaacac caagtgatag agtcttgaca cgtacttttt catcagcgtt ttctttctta
    12361 gttgaaagga aagcgatgat atctgggtga aagacgttga ggtagacaac accagcacct
    12421 tgacgttgcc ccaattggtt ggagtaagag aagctgtctt caaaaagctt cataacagga
    12481 acgacacctg aagcagctcc ttcatagcct ttgataggtg caccagcttc acgaaggttg
    12541 ctgagggtaa ttcccacacc accaccaata cgtgaaagtt gaagagctga gttgatagaa
    12601 cgtccgatag agttcatatc atccgtcact tggattagga aacaagatac caactcccca
    12661 cgacgagcac gtccagcatt caagaaggaa ggagtagcag gttggtagcg ttggtggatg
    12721 atttcattgg caatatcgat tgcaacagct tcattcccat cagcgaaata aagggcgttg
    12781 aagaagacac ggtcttccat attttcaaga tagtattcac cgtcattagt ctttaaggca
    12841 tattgattgt aaaatttata agctgccatg aatgacttga attggaagtt ttggtctttg
    12901 ataaattgag ccaattcttc caagaactct ggacggtatt tcttgataaa ggctgtttcg
    12961 atgtagttgt gttcaatgag gtaattgatt ttgtctttga ttgaatcaaa aaccatagtg
    13021 tttggaacta cattttcttt aaagaaagca tccaaggctt ccttatcttt atgaagcatg
    13081 atttgtccat taacaggacg gttaatttcg ttattaagac ggaagtaagt cacgtcttca
    13141 agatgtttta atcccataaa atttccctta tctaattaca aaagaaaggc ttctaagtta
    13201 gccctaaaag cagtttcttc tggatgatgt actaagatta tgctaattgt ttcagttttc
    13261 ctggttggaa acctgaaaag acttcagttg gtgtttggat aacaggagct gcgctaaaac
    13321 cgagctcttt aacttgatcg acgtactcag gttgctcatc aagattgatt tcacgataag
    13381 agacattatt actgtccaag aaacgcttgg tcattttaca ttggacacaa ttgtttttag
    13441 aataaacggt taccattgtg taactcctct tcaaaattta atactatctt agtatatcag
    13501 aaaataaaat tttgtcaatg atttgaacta aatatagtgg tgttcttttg ttgtttttat
    13561 atataaacac aatatatagt gtttgtattg tgaaatagca atgattatcc tataaattgt
    13621 ttttaaagaa actatatcct gtgttttgtt atctaggata gaagattttc agcaagttat
    13681 ctgaaaggaa attgaaggaa aatccagaaa atgcttgaaa aaaatcctag aagatggtat
    13741 aatactaaat tgtaagggtt atcacatata actcaaaaaa agaaagaaca aaaggagagt
    13801 caaactatgg cttctaaaga tttccacgta gtggcagaaa caggtattca cgcacgtcca
    13861 gcaacattgt tggtacaaac tgctagcaaa tttgcttcag atatcactct tgagtacaaa
    13921 ggtaaatcag ttaaccttaa atcaattatg ggtgttatga gtcttggtgt tggtcaaggt
    13981 gctgacgtaa ctatctcagc tgaaggtgca gatgcagatg acgctatcgc tgcaatctca
    14041 gaaacaatgg aaaaagaagg attggcataa gggaaatgac agaaatgctt aaaggaatcg
    14101 cagcatctga cggtgttgca gttgcaaaag catatctact cgttcagccg gatttgtcat
    14161 ttgagactat tacagtcgaa gatacaaacg cagaagaagc tcgccttgat gccgctctac
    14221 aggcatcaca agacgagctt tctgttattc gcgagaaagc agtaggtacg ctcggtgaag
    14281 aagcagctca agtttttgat gctcacttaa tggttcttgc tgacccagaa atgatcagcc
    14341 aaatcaagga aactatccgt gcgaagaaag tgaatgcaga agcaggtctg aaagaagtta
    14401 cagatatgtt tatcactatc tttgaaggca tggaagacaa cccatacatg caagaacgcg
    14461 cagcggatat ccgcgacgtg acaaaacgtg tattggcaaa ccttcttggt aaaaaattgc
    14521 caaacccagc ttctatcaat gaagaagtga ttgtgattgc gcatgacttg actccttcag
    14581 atacagctca attggacaaa aactttgtaa aagcttttgt aaccaacatt ggtggacgta
    14641 caagccactc agctatcatg gcacgtacac ttgaaattgc tgctgtatta ggtacaaaca
    14701 acatcactga aatcgttaaa gacggtgaca tccttgctgt taacgggatc actggagaag
    14761 tgattatcaa cccaacagat gaacaagcgg cagaatttaa agcagctggt gaagcctatg
    14821 cgaaacaaaa agctgaatgg gcacttttga aagatgctca aacagtgact gctgacggta
    14881 aacacttcga gttggctgcc aatattggta ctccaaaaga cgttgaaggt gttaacaaca
    14941 acggtgcaga agctgttgga ctttaccgta cagagttctt gtacatggat tctcaagact
    15001 tcccaactga agatgagcag tatgaagcat acaaggctgt tcttgaagga atgaacggta
    15061 aacctgttgt cgttcgtaca atggatatcg gtggagataa ggaacttcct tacttcgata
    15121 tgcctcacga aatgaaccca ttccttggat tccgtgctct tcgtatctct atctctgaga
    15181 ctggagatgc tatgttccgc acacaaatcc gtgctcttct tcgtgcgtct gttcacggtc
    15241 aattgcgtat catgttccca atggttgcgc tcttgaaaga attccgtgca gcgaaagcag
    15301 tctttgatga agaaaaagca aaccttcttg ctgaaggtgt tgcagttgcg gataacattc
    15361 aagttggtat catgatcgag attcctgcag cggctatgct tgcagaccaa tttgctaaag
    15421 aagttgactt cttctcaatt ggtacaaatg acttgatcca atatacaatg gcagcagacc
    15481 gtatgaacga acaagtttca tacctttacc aaccatacaa cccatcaatc ctacgcttga
    15541 ttaacaatgt gatcaaagca gctcacgctg aaggtaaatg ggctggtatg tgtggtgaga
    15601 tggctggtga ccaacaagct gttccacttc ttgtcggaat gggcttggat gagttctcta
    15661 tgtcagcaac atctgtactt cgtacacgca gcttgatgaa gaaactcgac acagctaaga
    15721 tggaagagta cgcaaaccgt gcccttacag aatgctcaac aatggaagaa gttcttgaac
    15781 ttcaaaaaga atacgttaat tttgattaat cgaaaagtcc ctgcaactca gttacaggga
    15841 ctttttttga tattttaaaa agaattttca agaaaatctt tcttataaaa agtccaacct
    15901 tgaaaaagta gtggtcagaa caaaaaatac ttaaatggtt cataaaattc ttgacaagtt
    15961 ggagatttag gagtaaacta ttaaccagtt aagtaataga gaggagtttc tgcaatttag
    16021 aaatgaattg caactagaaa tatcaaatag aaagagagtt tcgatgaaaa ttaataagaa
    16081 ataccttgtt ggttctgcgg cagctttgat tttaagtgtt tgttcttacg agttgggact
    16141 gtatcaagct agaacggtta aggaaaataa tcgtgtttcc tatatagatg gaaaacaagc
    16201 gacgcaaaaa acggagaatt tgactcctga tgaggttagc aagcgtgaag gaatcaatgc
    16261 tgagcaaatc gtcatcaaga taacagacca aggctatgtc acttcacatg gcgaccacta
    16321 tcattattac aatggtaagg ttccttatga tgcgattttc agtgaagaat tactcatgaa
    16381 agatccaaac tataagctaa aagatgagga tattgttaat gaggtcaagg gtggatatgt
    16441 tatcaaggta gatggaaaat actatgttta ccttaaggat gctgcccacg cggataacgt
    16501 ccgtacaaaa gaggaaatca atcgacaaaa acaagaacat agtcaacatc gtgaaggtgg
    16561 gactccaaga aacgatggtg ctgttgcctt ggcacgttcg caaggacgct atactacaga
    16621 tgatggttat atctttaatg cttctgatat catagaggat actggtgatg cttatatcgt
    16681 tcctcatgga gatcattacc attacattcc taagaatgag ttatcagcta gcgagttggc
    16741 tgctgca
//
LOCUS       DAVBOU010000048        16453 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBOU010000048 DAVBOU010000000
VERSION     DAVBOU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16453
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.048"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ879_001716"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ879_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3143831.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ879_001717"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ879_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3143832.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ879_001718"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ879_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3143833.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ879_001719"
     CDS             3205..3600
                     /locus_tag="VQ879_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3143834.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ879_001720"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ879_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3143835.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ879_001721"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ879_001721"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3143836.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ879_001722"
     CDS             5389..5994
                     /locus_tag="VQ879_001722"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3143837.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ879_001723"
     CDS             5981..7180
                     /locus_tag="VQ879_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3143838.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ879_001724"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ879_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3143839.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ879_001725"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ879_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3143840.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ879_001726"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ879_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3143841.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ879_001727"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ879_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3143842.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ879_001728"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ879_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3143843.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ879_001729"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ879_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3143844.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ879_001730"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ879_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3143845.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ879_001731"
     CDS             14213..14926
                     /locus_tag="VQ879_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3143846.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ879_001732"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ879_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3143847.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ879_001733"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ879_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4948 a         3074 c         3687 g         4744 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcaaaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaatttat ttg
//
LOCUS       DAVBOU010000049        15004 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBOU010000049 DAVBOU010000000
VERSION     DAVBOU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15004
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.049"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..245)
                     /locus_tag="VQ879_001734"
     CDS             complement(<1..245)
                     /locus_tag="VQ879_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3143848.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFS"
     gene            complement(344..1123)
                     /locus_tag="VQ879_001735"
     CDS             complement(344..1123)
                     /locus_tag="VQ879_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3143849.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(1120..1293)
                     /locus_tag="VQ879_001736"
     CDS             complement(1120..1293)
                     /locus_tag="VQ879_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143850.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(1823..7036)
                     /locus_tag="VQ879_001737"
     CDS             complement(1823..7036)
                     /locus_tag="VQ879_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3143851.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(7080..13559)
                     /locus_tag="VQ879_001738"
     CDS             complement(7080..13559)
                     /locus_tag="VQ879_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3143852.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVSGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEPSKEYTGVQAGAIVEPEQIAPLPEYTGVQAGAIVEPEKVEALKEYTGKIEQPS
                     AEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTGVGSATFIAPNVLLTVAHN
                     FINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIHFYNKKDYPKGFIYDLAVI
                     KLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLKDATVEMEQEYANNTYGVQ
                     YQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPTQLAWIKSIIAGNEIPPVY
                     DELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGNKYRHVTSLASLPSNAENY
                     FMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLIQHENNNVLENYTYYLPKT
                     QQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELPDGQESYVNNVFHGILVGT
                     NNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDTATLAKEANNNTHIDNVHA
                     DGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVASYQIGGLVGKLSGPRGLID
                     KSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGNLNNVQRFANVGGVVGNLW
                     DPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGTYSNKNNKVVNVVQEDDEI
                     LTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSSRYVTDYKNLENADSSKEK
                     VYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVPMKDKEVISDINKNKSSIN
                     KLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPNTLLRNYQNILDEVLPALN
                     SVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDSLTKLLTADAAIAENNNKV
                     IDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLVMYHLDFFGKSNSSALDNV
                     IELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKYRKAFVPDKTNNEWFKEQT
                     KAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKYPSMVLPLLTLPEKSVFII
                     ANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRFRDHYDYWYRILDDKNKEK
                     LYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFGPAGNNVVHNSNGAYATGD
                     AFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNGLGPEFYAKGLLQAPDHPN
                     DPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYMHNMFDVIYMLEILEGKAV
                     AKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPEELTKLTTFNSLIEHDIIT
                     RRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMGRRIAFELLAAKGYKDGMV
                     PYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNNQYNSWIDFKKDMYKERED
                     KFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVKFDAEDEVAKLYPETNSRV
                     LKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(13768..14946)
                     /locus_tag="VQ879_001739"
     CDS             complement(13768..14946)
                     /locus_tag="VQ879_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143853.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         4245 a         3022 c         2227 g         5510 t
ORIGIN      
        1 attgaaaatg cttgacaagg gaatccccca cagatgatat cgactttccc tctaagtttt
       61 ttaaattctg catctgaaac atctcgtatg tcatgaaatt ctatttctcc ttccgtttga
      121 aaaatggact tataagattt cctagcaaat ttatcaatct cacaaaatcc aatacactcg
      181 tgtccaacac tttccattcc aagtcgaaat ccacctatac ctgaaaataa atcaataaat
      241 ctcatttctt gatcacctct ttcttatcga ctaccattgt cataactgtc actccacttg
      301 aaatgacaat aagcataact aatatccact cgattgacga catttaacca cctccttttc
      361 taacacggtt attccaaaca gaatacaggc cattaaacac aaattcagca agtacttccg
      421 ctcgtctaac aaagcgaaca ttgtcaagag catactgata gattctttca aaatcagtca
      481 tagcaatttc actggctgtt tcagaaaaac cttctcgtct aaattgatct tgtaccaatc
      541 cccaaatata atctcgatca tattttgtga ccttttctac ttttcttttc aaaataggtt
      601 gagtattcct atcctcctca tcctcaataa ataaagaatc agtctcacta tatttagtct
      661 cactaacttc agtctctcta ggggctgaat gtgagactgg ggccgtttca ttttcaacct
      721 gccctagtct ttttttaaca ctaggcctgt ttgaattacc tactggggta gaagataatt
      781 cccctaaata aatcttatta gctagtcttc ctttctcact tgaagactgt tgaacttcat
      841 caattaagtc atattcttta agaatttttt tgatagacag taattttgac ttcgagcaac
      901 ctaacagctt catcagttta gaattagaaa atactaaata aaccgctcct tcttcatcta
      961 tccaaccacg actgagagat aattctaaac gatcttttaa aatagaataa gccaccttta
     1021 cttctagttt catatccata tatttctcat cctcaaaaag aattttaggt aatttgtaat
     1081 accgttctga agtttggtat tgatttgcgg taattcgttt catagcgcac ctccaagttc
     1141 tttgagtgtt aaatctccgc ttgattccaa ttgaaccaag ccactttttt ccaattcagc
     1201 cataagagag atggcttcaa caatgtcaat tcccatttca cgtactaaaa atgaaatgac
     1261 aatatagcgt gatgattgta attcttttgt cattttccct cctgaaaata aaaaaaacgg
     1321 aaagattgtg aaattccttt ccgtaacata ataaatattt gaacaccaaa ctcaacacca
     1381 aaaaaatgtt tttattgata attattgctc aatcaagcac ttataacaat gtaaaaaata
     1441 aaaatctgta ctcacaaaaa cccttgaaat tcaagggttt taagcattta ttctacttca
     1501 caatgtttta ttattttaaa tcttctagac caaccattga atagtagcca ttgagttttt
     1561 tcctttcgta gcaaggattt agatccccta ttttatttta ctatagtttg aacatagaga
     1621 gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat ctactttata
     1681 ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct tttagcctat
     1741 cttttaccct atatagaaaa aagccatcaa atgatgactt ttcagaggga gcaaaaaact
     1801 gttccttcta tattctaaac atttaaatgt cttctttaaa cagtttatta aagaaaccgt
     1861 ctgtgttttt aagaagggct ttgaagacct tagatttaag agcaacagtg tgagagaagt
     1921 catctggttt cttcaaatct tcttcaactg ctttatcaaa taaaggcctt aactcatcat
     1981 agttactgat atggacgcca tcaatatcga tagcctcaaa acctttctta gctttagcaa
     2041 gaacttcccc gtaccaatgt ctcttccact cttcaagagt attaaagttt cctttcgata
     2101 ctttattaat tattagctta tcgcttagta aaccgtggtt gtttttatct gcttctgctt
     2161 tgtatttatt tgatacataa ctaataaagc cattttcata accataatag ccccacatac
     2221 ggaaagcatt gtgcttaaat gataatgaac caggagcacc ttgactcgta ttcccaccgt
     2281 aaattcctgc catcatattg acatttacgt aagctgagtt tggtgtaaaa tcttctggtc
     2341 tataacgtcc attacctgga tttccatgtt ttgtcatgaa gttattatcc actaaatcat
     2401 tgacgctaga taaagtcatt accttttctt catctttcaa atcacggata ctatcccatt
     2461 ggtttggacc taaaagatca ttatactgaa tcttagagcg catttctttg tcaatcttct
     2521 tgaaccactt actattgtct cctttaattt taggaagtac agcatcagct tctacatgat
     2581 caagcaacat catagcttca ttgtagtttc tcatgtagcg gtcaatgtca tcacgtgtct
     2641 ttaatttgtc aggatctggg ttgtaccatt ggttaccatc atttggacga tggtaagcca
     2701 tgttaattcc aagtgcgccg tattcaccat tagtcgttga gctgtcaggt gtttgcaaca
     2761 taccttgagc ataggcttca acgtctgtac cttgacgatg cttatgacca ccgaagtaaa
     2821 gcattctatc gtttacgtgt gttgtttcgt gagtaaaggc tgaaatacca aatgggctaa
     2881 tcatatccgt caccataaac aagaccttgt catcattatt tggattaggg aatattgatg
     2941 ccatagcgcc catacgccag tctctatcat ggtgtcgcca tgttggacca tataattcac
     3001 gaattggagc tatagggtta cctttactgt caaatcctcg acgacctaca ggagaaccat
     3061 tgtaggtctg gttatcccaa actggtgtcg gtaccatatt ttgactctta agaagtctat
     3121 cacgaacatt aggcagagct aatctggacc agaaatctaa ataagtttgt tgagcatgtg
     3181 caacttcatc aatcttagtt ttgaactcat tacgagcttc ttctgtatgt tttccatatt
     3241 tctcaaatga actgtacgcc atcgtgttat atgttgaaat taagaacata tgggcatctt
     3301 taagcgttag aagtggtaaa atcatacgac catgaacacc gttatctaaa ccatcgaaca
     3361 cacgatgacg tttatctttc aactctgtat ttgttgtctt aggttctgaa acataaacat
     3421 tcttagctga gtggataaac caatcattga tgtctttatc ctctgtaaac agacgcatgt
     3481 tgtattctaa gaagttacgc aaattacttt taccagtatt acctgcgatg atttcacggt
     3541 aagcatcctg agtccgatcc cctttcaagt tcttttcact tgaaccgatg ttgatgagtc
     3601 tgtcaataac acttggtgtt ttaccataaa aatcaggttt gaacatcatg atgtttttta
     3661 tacttatgtc accgtatttg atatcatagt aacgattgag ataagtcaga gccatcatga
     3721 ttttagcttt attggtttcc actttcttga gaagtgattt tatcgcagct tcatcaccat
     3781 tcaattgatg gtcttcattt tcgaccaagg atttgactaa cttatctaga ttttgcttca
     3841 cttcggcaaa gctttcttct aagtatagat ctttaatata accattctta cgttcatccg
     3901 tattctctgc aggtttatca cgtctactca ttaaatctct tacttcttgt gaaatcaatt
     3961 ccacacttga taattgagat ttaacatcag caatcaattt atcacgattt ttaacaacca
     4021 tattcggtgt ataaacaaca tcaccaagac cagatacact atattcacgc acttgttgga
     4081 ctttagaatc agtattctta gtaacatcca tttcttcctt agtaccatca gcatagtgaa
     4141 ccataatctt atcaatatct gataaatcgg tcacgaattg accatccttc atccccgtaa
     4201 cagaaaggac ttctttctta gctaagtttg aatcttctgc aagtttgtta ccttggttga
     4261 caatccattc tttattataa aatggttgaa gtttctcaat attacgataa gctaaatcac
     4321 gttcggattt gtagtcttga gttgacttat attcatcttc tcttctggtt aaacgattta
     4381 agcgattgac cacaggttcg ttgatttcgt atttatcagc agtaagtcca aaatttgcaa
     4441 ttctcttatt agcttcatct tgactaattt ctttaatttt gtcacgagaa cgtttgtatg
     4501 aatgcttacc tgaactgaca cctttgacaa caaagttacg ctctaaccag ccatttgtga
     4561 aataaccacc atcgtagtcc aaatcggaag aaccaaagaa ctcttcacca ttttcaactc
     4621 tcatcattga aatattatct tcaagtttac caaaaggaag attgctattg ataaatccac
     4681 ctgtttcaaa caaaacttta gtcttaatgg ttcctttggt gactgattta cgaattgaac
     4741 cgtatttacc aattcccata gagtcgttac cattatctgt tttagcaact aaaccaccta
     4801 tacgggctct gttagcaaca atatcagcct cgacatatgc ttttgcaaga ttacctctcc
     4861 aaatctcacc ggcaatgcca gccatatatt gacctttatc accaacacct gtaagattac
     4921 cgatgaaggc tacatttgtc aactgaccac cactatcgat tttattgacg atacccgcaa
     4981 tattgttatt agcaactaca ttaccagtta ccttaacatc ttcaacagtt gcatttttca
     5041 ccatattggc aacaggtgct attccgtcag cccaaggcat attgatatcc acattaccta
     5101 aattaatatt tttcacagaa ccattttcaa cacggtcaaa taagggacgg gcaatgttat
     5161 gaattgtata ttgtttacca tcaacacttg atagatgtcc cttaaacgta cctggaacat
     5221 attgtttgtt aggtgttggt acattcgttg cattcaaatc tgctccgatt ttaaatgtac
     5281 catttttatc agcattcatg gcatctacta actctttaaa gttataataa acgtcatcaa
     5341 cttttggaac tggtttttca atataatgaa catacttgtt acgaaccttc gttgggtctg
     5401 tatgttgaat caaatcttga gcttcggcag tgattttata aagtttctta ccttcttcag
     5461 tcacttcttc aattttatca actgctaaac gtgttacttt attatcacga ctagtaattt
     5521 ttaagtacat tttcttcaca tcttcatctg aaggtttttc agtcataaaa tcactaggtg
     5581 tttcagtacc atcgtcattt accttcacta aattagtaga tgcgatattt ttaatttcaa
     5641 cttttttcaa atccaagcga agtggtttct cttctaatgt tgcagtttct tctcccttgc
     5701 cacggtcata ggtcatagtg gtctctatct tatagtcctt gtagaatttt aaatcttcta
     5761 cctgcttatc taattgctct gaagtcaaat ctactgtttt gacaatttca tttccatctt
     5821 taattgtcgc agtaatttta ttgattgtga ctccatctgt attaactaaa tgataagaaa
     5881 gagttgcgga tcggtttaat acatttgtat ttgttctatc taaggtcaaa acaggagccg
     5941 ttttttcttt aggtttttct ttggtacctt ttacaagaat tttaggcttc atttctttca
     6001 aaatagttac tgtttcaact gggtcactga tttttttgcc atgtaactct tcatagctag
     6061 taacaatttg acgttcgcca tcctcaccaa cttgtctaac agaatcatcg cctataaatt
     6121 tgctaggatc agattcttct atagtggttt taggaatagt ctctgtccga atatcggtat
     6181 gtaaagaagg caactcttct ctttctgatg caacttctga aactgtagat attggttcag
     6241 tatactctgg aatgtcgcta acaggtggct caatcaagtt tccattttca tccactcctg
     6301 ttgtacctac tggctcagta tattctggga tgtcgttaac aggtggttca atcaagtttc
     6361 cattttcatc tactcctgtt gtccctactg gttcagtgta tgctagtttc tcatgaactt
     6421 caggctcaac aaggtttgca cctattggtt gcgtatagtc aggcttctca tgaacttccg
     6481 gttcgccttt ctctgttaca actttgggtt gctcaactgg cgaaacagtt gatgctggag
     6541 aaaccgacga aacagtttta tcatcaagct ccaagtaacc aacatatctg taaccagaaa
     6601 tttgcaacac accatcacgt ccagactcat ggatgttagc attcaaatta agtgctgaag
     6661 cagttgatag tgtaactaaa cctgtcgccc ctacaatcaa aaatgtagct atttttttat
     6721 ttctattatc ttttgtgata atcacaataa gactcccgat agctaacaaa cccaatgcag
     6781 tcataataga ttgagaactt cctgtgtttg gtagtgcgtc tttttcataa tccaaagcat
     6841 atgactcttt ggattcatca ggtctacctt gtttgagttg atcacgttca gtttgtgtca
     6901 aactactata atctaagtaa tgataagtcg atgcaccaac aactgacggt gcaaataaaa
     6961 gactccccaa gaataccgaa ccaacaatac cctttatttt ccgaatggaa aatttatctt
     7021 tttttaataa tgacaattct aatcctccac cttcactttt tatttcctaa tagtaaacac
     7081 tattttttat tctcaaaaat tgaacttcta aaatcaccgg tttggtcaag ataagcttta
     7141 aagattgctt ttttcagttt aagaactcta ctatttgtct caggatataa tttggcaact
     7201 tcatcctcag catcaaattt tactgcatct tcaatcattt tttcaagtct attaatatta
     7261 tcaatagtca ctttctgttg tcgagcccaa gaaccgtttg gatcgataaa actaacttta
     7321 tttaactttc caaatttatc ttctctttct ttatacatat ctttcttgaa atctatccaa
     7381 gaattatact ggttattaaa tacttttgaa agaacaattt catcagtaac taaacctatt
     7441 tgtttaccat atgatgtaat aacttttcct tgagctttcg cttctttttc atactgatta
     7501 gaaatatatg gaaccatacc gtctttgtac cccttggctg ccaataactc aaatgcaata
     7561 cgtcgtccca ttaaatctcc tggtgttcct attttactgc tcaatgctga ataaattggt
     7621 gagaatagat taattgtata gtagccattc cgcttataag ttgcttcatc tacataacct
     7681 cttcttgtta taatatcatg ttctatcaaa ctgttaaatg tagttaattt agtaagttct
     7741 tctggtttta atctacgtac aacattcgtt gcataaacag aatttccatc aggatcaggt
     7801 ttatattcat tttctatttt tcttaataaa tcatattttt gatttgtatc taatttagct
     7861 acagctttac cttctagtat ttcaagcatg tatattacat caaacatatt atgcatatac
     7921 ttatttagat catcaacact tccaaatcgt tgagttggat ctgctacttg aagccttgtt
     7981 gattcttctg attgatcata ttttaatatg gaattaatag tgactgttgg atcattagga
     8041 tgatcaggag cttgtagcag tcctttagca taaaactctg gtccaagtcc atttcgtctt
     8101 ccatagcctc caagataaat ttctctatct gagttatgtg tcatttcgtg tgtataagtt
     8161 accgcaccat ctttatcaag catgcgatat gccatataat agaatgcatc ccctgtagca
     8221 tatgctccat tagaattatg aacaacatta tttcccgctg gaccgaagaa atgttttata
     8281 gctggatgat tagtttcaaa agttgcttga tatgtatctt tatcttcttt ttcatctgta
     8341 ccaaatctaa atgcatcata gactagaaca cttctatata atttttcttt atttttatca
     8401 tctagtattc tataccaata atcatagtga tctctaaatc taacagccgc ttctttagct
     8461 tttttctcaa catagtcatt taaatcagtt cctgctggat gttctttact tctatatcta
     8521 tcataagcac cgaaacctat agtcgaaatg ttggctataa taaacaccga tttttcaggt
     8581 aatgttaata gcggcaacac catacttgga tatttccaag atgggctagt taatctatca
     8641 tatactccaa ttgaatatgg actaccagct attgattgct tatcacttac ctctttaata
     8701 gtagattttt cttctacaat atatgcttta gtttgttctt taaaccactc attatttgtt
     8761 ttatctggta caaatgcttt tctatatttc tctaatgcat caaataaatt attagtctta
     8821 taatttttcg ctaataaaac attataagtt ataacattat tttttgctag taagttatta
     8881 tatcccgatt tacctagttc gataacatta tctaacgctg aactatttga tttaccgaag
     8941 aaatccaagt ggtacatgac taaatctttc gcttttgtat cacgatattt gaagtcgtac
     9001 caacgctcta agtatgttaa tcctagaagt aaagcttctt tattattttt aattttctcg
     9061 attacataat tatctattac cttattgtta ttttcagcta ttgcagcatc tgcagtaaga
     9121 agttttgtca aactatcttt caaattagtt tttgtggtat tgaattgttc ttctaaatat
     9181 aactccgtta aactaacatc cttagaaaca tctaatactt ttctaattgc ctctgattta
     9241 tattctacac tatttaatgc tggtaatact tcatctaaaa tattttgata attgcgaagt
     9301 aatgtattcg gtgtataaat taagtttgta ccgcctattc tatactctgc tacatttgaa
     9361 aaatcagttt gataatttac attaagtgtc tctgatgtat tatccgcgta atatagtaat
     9421 agtttattta tacttgattt atttttgtta atatcactaa ttacttcttt atctttcata
     9481 gggactactg acaataattc tttattataa agattactac ttgtctctac taaatttccg
     9541 tacttaacaa ttgtttctct attataaaac ggtaatagtt tttcaatatt tttatatact
     9601 ttttcttttg atgaatcagc attctcaaga tttttatagt cagttacata tctagaagag
     9661 aaattaaaat cttctgtttt aatagtattt ttagatacaa aagtagcttt tttctctttt
     9721 atttgtgcat cttctaatac ttctcctctt tgaacagtag aatccttagt taagatttca
     9781 tcatcttctt gtactacgtt cacaacctta ttatttttat tactgtatgt gccatttgct
     9841 tttataccat taaaattata acctgcaata gcattaccat tcgttacatt aacatcgctt
     9901 agtacattag aaagtcgacc ggatttttct aatcctccaa ccggatccca aagattacca
     9961 actactccac caacgtttgc aaaacgttga acattattta gatttccttc agcataacta
    10021 ttactaataa gcgcactatt ttctactgca ccaactattc caccaataga ctggtctcct
    10081 tgtgttgcat ttgaagataa atcgattgat gcgaacgact tatctattaa tcccctcgga
    10141 ccagaaagtt tgcctactaa acctccgatt tgataactag caactgtttt atatgtatta
    10201 gttattctac ctgtatagct actgttagaa atagtagaat tattaacttg tgatactaat
    10261 cctcctatgc tacgttcccc agctatcgct ccatcagcat gaacgttatc aatatgagta
    10321 ttgttatttg cttctttcgc aagtgttgca gtatcgtcct ttgcggaaat attaacatct
    10381 tttagtgaaa gtttttctac tgtagcacca tttaattccc caaataatgg ttttttcaaa
    10441 ttataaatag cataatattt ctcattattt gttcctacta atattccatg gaatacatta
    10501 ttcacataac tttcttgacc atctggaagt tcaacttcac gagcatccat agttgctcct
    10561 aaacggaatg tgccattagg attgctattc attgcatcta ctaaattttt aaatgatgta
    10621 tataccccag tttcactttg ctgagttttt ggtaaatagt atgtataatt ttctagtaca
    10681 ttattatttt catgttgtat cagactattt gcacttgcta ctatcttata aacatctcta
    10741 ttatctttag tatcattagt aatgcttgta actggtagca tcacatcttt aaagttctct
    10801 gatttaactt tcataaagta attttctgca ttacttggta aagaagcaag tgaagttaca
    10861 tgtcgatact tattaccatc ttttgaatat agttctacag aagatatatt tctaagttct
    10921 aatttcttaa taacttcttt ttcatcttta gcgtcatctt ttttctcatc tttatgacga
    10981 taaagttcat cgtatactgg tggaatttca ttacctgcta taatactctt aatccaagct
    11041 aattgtgtag gagataaaat caatccgcct gagcgatttt gtgctccatt ttgatgcaca
    11101 ccaataactt caccattagc attaaatatt cctccaccac tcataccagg atttccacct
    11161 tgatattgaa caccgtaggt gttattcgca tattcttgtt ccatttctac cgtagcatct
    11221 tttaagtgcg tatatttccc agctggatat ccatgaacat ttagtttgtc attaagattt
    11281 actttcgaat aatttttaac taattctaca tgttctctgc cagttgtttc aggtagctta
    11341 atcactgcta aatcatagat aaatcctttt ggataatctt ttttattata aaaatgaata
    11401 ttgttagcag taaatgttcc tttttgtcca tcaggagtca cccactcata tacgttttta
    11461 gatttatcac ctctaaattc gccagtagta ttatcagtag aattattaat gaaattatgt
    11521 gctactgtta aaagtacatt tggtgcaata aaagtagctg atcctactcc agtaaccttc
    11581 gacgaatctg taataaagtt catattaatt aatgcactag attttttctg aatactcatt
    11641 tcttctggtg tattagtatt ttcattattt ggtttagtat cttctgcact aggttgttcg
    11701 attttaccag tatattcttt cagtgcttct actttttctg gttctactat tgctccggct
    11761 tgcacccctg tgtattctgg tagtggtgct atctgctctg gttcaacaat agcgccagcc
    11821 tgcacccctg tgtattcttt tgatggttct actttttctg gttctactat tgctccggct
    11881 tgcactcctg tgtattcctt cggtgcttct accttctctg gttcgactat cgctccagcc
    11941 tgcactcctg tgtattcctt cggtgcttct actttctctg gctcgactat cgctccggct
    12001 tgcacccctg tgtattctgg tagtggtgct acctgctctg gttcaacaat agcgccagct
    12061 tgtactccag catattccgg ttcaactttt tcaggttcaa caatagctcc agcttgtact
    12121 cctgtatatt ctggtagcgg ttctacctgc tctggatcac ccttgtcagt catgactgcc
    12181 tctggtaacg ctggttgaac ttctggtacg cctttatcac ttactacagc ttctggcaac
    12241 tctggttgga ctgctgactc acctttgtcg gttaatacag ctgctggtag ttcaggctga
    12301 attgcgggtt caacaatagc tccagactgt acttccttat gttctgcacc agtctcagct
    12361 tgttccttta taacttgagc ttttttagta cctttttcga ctattcttga aacaggcgca
    12421 gtcgttgaag ttgaaataat ttctcgtgaa acttcttcat tgtttacaga aaatattctg
    12481 acgatttcaa ctttcttacc taatgcacct tcttgtttta ctcttacagt tccttctgct
    12541 aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtttctat agtttcgtca
    12601 cgatataaga gttccggttt gttcaactga cctgatagca cttcatcctg tggatttaat
    12661 gtatttaccc cagtcttttc ctttggagaa atcttctcct ctttcttcgt ttctagattc
    12721 ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt tcttggattg
    12781 attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt agttgaagaa
    12841 acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa atttggtgta
    12901 acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc ttgattactt
    12961 acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt gtaacctgaa
    13021 atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt attgtaattt
    13081 agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc cattcccgca
    13141 accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac agcaaaaatt
    13201 aaaattccca gagcagctaa gctagcacca gaaactaggg cttgcctctc attcttgctt
    13261 ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac aagataataa
    13321 gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt cttttcttct
    13381 gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc ttgagcatcc
    13441 acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc agatacaagt
    13501 cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata cttttccatt
    13561 attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat tagtgtatta
    13621 tctattatct atagaaaagg cagtatacct taattatact cttaatttac aaaaaagtct
    13681 taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca ataacaccta
    13741 ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa atggtttgag
    13801 gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat ggtcttcctg
    13861 caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt caaaggcttt
    13921 cattttatag aaaaagtcga tgagatgatc ggacaggtat tcagttgaaa agggtacttc
    13981 accacttttt cgatattcta ataagagcct agaaaatcga gctttttctt caggaagctc
    14041 acgaaaatag gaattgagga gccaagtctg cttctgtttt ctttcaattg gatcctgact
    14101 ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga tagcccgttc
    14161 tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag tcagggtctc
    14221 tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta gaaccagatt
    14281 gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg cctggatacg
    14341 gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga gttggtcatc
    14401 cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca tccgagcctt
    14461 tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga aaagctggta
    14521 gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt tttcccagag
    14581 ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt cttttttctg
    14641 agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt ccaattgctg
    14701 gtcaagggac aatcgatgaa aatgacgaac acagtcgcta ccaattggaa agaggcgttg
    14761 gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttccac agacacaatt
    14821 gctacggccg ataccgttaa aaatcaagga aacttcattc cattccttgg tagcttgttc
    14881 ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc taactggaag
    14941 tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta gaaagctagc
    15001 cgca
//
LOCUS       DAVBOU010000050        14716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBOU010000050 DAVBOU010000000
VERSION     DAVBOU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.050"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ879_001740"
     CDS             83..880
                     /locus_tag="VQ879_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3143854.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ879_001741"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ879_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ879_001742"
     CDS             2383..3657
                     /locus_tag="VQ879_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3143855.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ879_001743"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ879_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3143856.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ879_001744"
     CDS             4786..5088
                     /locus_tag="VQ879_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3143857.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ879_001745"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ879_001745"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3143858.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ879_001746"
     CDS             5962..7302
                     /locus_tag="VQ879_001746"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3143859.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ879_001747"
     CDS             7280..7492
                     /locus_tag="VQ879_001747"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3143860.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ879_001748"
     CDS             7489..8364
                     /locus_tag="VQ879_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3143861.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ879_001749"
     CDS             8357..9172
                     /locus_tag="VQ879_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3143862.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ879_001750"
     CDS             9165..9596
                     /locus_tag="VQ879_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3143863.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ879_001751"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ879_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3143864.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ879_001752"
     CDS             11272..12000
                     /locus_tag="VQ879_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3143865.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNCGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ879_001753"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ879_001753"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3143866.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14061..14141)
                     /locus_tag="VQ879_001754"
                     /pseudo
     CDS             complement(14061..14141)
                     /locus_tag="VQ879_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14315..>14716
                     /locus_tag="VQ879_001755"
     CDS             14315..>14716
                     /locus_tag="VQ879_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3143867.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGN"
BASE COUNT         4383 a         2661 c         3477 g         4195 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgaa attgtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aactgtgttt tgagtaacct
    14101 gcggctagct tcctagtttg ctctttgatt ttcattgagt attagaacag aaaaatgctt
    14161 ggagtatttg tttgtgtgtt tatttttata taacaaacta taaacaaaac aaaaatataa
    14221 aaaaagagac aaaaaagaat agaaagtaat taacaacgat ttcatatagt gttatactta
    14281 tagcataaag ttaatggaaa gaagggaaaa ccttatggta ttagattatt tctttgacaa
    14341 aaaccttgtg ttttgcttag aagcggataa tcaagaacaa ctctttgatc aggtagcaag
    14401 cttgttggaa gaacgagaaa ttgtcactcc aacttatcgt gaagccttga tcacgcgtga
    14461 aaagtcattt ccaactggtt tagatatgga atttctagga aaggacttgc caaatgtagc
    14521 gattcctcac acagatattg ttcataatct agctgaaaaa gtggtggttg ttcgattaga
    14581 aaaaccagta acttttcaca atatgattgc gccaggtaag gaagtagaag tatccctact
    14641 cttctttatc attaacaatt caagttcaag tcaaacaaat attctggctc agttgatgga
    14701 ctttttcaca ggaaat
//
LOCUS       DAVBOU010000051        14344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBOU010000051 DAVBOU010000000
VERSION     DAVBOU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.051"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(83..646)
                     /locus_tag="VQ879_001756"
     CDS             complement(83..646)
                     /locus_tag="VQ879_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3143868.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ879_001757"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ879_001757"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3143869.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ879_001758"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ879_001758"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3143870.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="VQ879_001759"
     CDS             2112..3782
                     /locus_tag="VQ879_001759"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3143871.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="VQ879_001760"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="VQ879_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3143872.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5341..6045
                     /locus_tag="VQ879_001761"
     CDS             5341..6045
                     /locus_tag="VQ879_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143873.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6038..7387
                     /gene="vicK"
                     /locus_tag="VQ879_001762"
     CDS             6038..7387
                     /gene="vicK"
                     /locus_tag="VQ879_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3143874.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7389..8198
                     /locus_tag="VQ879_001763"
     CDS             7389..8198
                     /locus_tag="VQ879_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3143875.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8289..8531
                     /locus_tag="VQ879_001764"
     CDS             8289..8531
                     /locus_tag="VQ879_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3143876.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8533..8787
                     /locus_tag="VQ879_001765"
     CDS             8533..8787
                     /locus_tag="VQ879_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3143877.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8834..9577
                     /locus_tag="VQ879_001766"
     CDS             8834..9577
                     /locus_tag="VQ879_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3143878.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(9867..10853)
                     /locus_tag="VQ879_001767"
     CDS             complement(9867..10853)
                     /locus_tag="VQ879_001767"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3143879.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ879_001768"
     CDS             11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ879_001768"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3143880.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            13515..14258
                     /gene="srtA"
                     /locus_tag="VQ879_001769"
     CDS             13515..14258
                     /gene="srtA"
                     /locus_tag="VQ879_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3143881.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4393 a         2477 c         3188 g         4286 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgatc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttattatag tttcaaacta taaagccata
     1981 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggacggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gatcttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgatctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atttgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtgcta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatcttttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga tttttggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatcca gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actctggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt tggtataata gtagagaaaa aggtgaacat
     5341 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
     5401 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
     5461 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
     5521 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
     5581 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
     5641 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
     5701 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
     5761 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
     5821 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
     5881 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
     5941 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
     6001 ttgacacgcc gtggtgtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
     6061 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
     6121 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
     6181 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
     6241 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
     6301 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
     6361 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
     6421 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
     6481 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
     6541 caatggtgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
     6601 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
     6661 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
     6721 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
     6781 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
     6841 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
     6901 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
     6961 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
     7021 gacgcaggtt gtcgacaata ttttaaataa tgctattaaa tattcgccag atgggggtaa
     7081 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
     7141 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
     7201 tgctagaagt cgtgcacaag gtggtacagg tctaggactg tctatcgcta aagaaattat
     7261 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
     7321 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
     7381 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
     7441 attcttttta tctggaaacc tcaaaaaata agcttttagt agatgcaggc ttgtctggca
     7501 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
     7561 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
     7621 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
     7681 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
     7741 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
     7801 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
     7861 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
     7921 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
     7981 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
     8041 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
     8101 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
     8161 cctcaccaga taccgcaaca ccattgacag agatataaaa agaacgctga gaaggtgttc
     8221 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
     8281 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
     8341 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
     8401 ccctagaaga tgaatacgat gctcgtgtgg caaatttagc ctatcaagag tatttagaag
     8461 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
     8521 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
     8581 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggc
     8641 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
     8701 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
     8761 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
     8821 ggagagtaaa aatttgaaga aaaaatgctt ttttgcagat tattatgata caacaattat
     8881 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgattgattt
     8941 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
     9001 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
     9061 tttattggct attctccctt taaatgctat tttcacagtt tttcgattag ggcgtatctt
     9121 tcgtttagtt aaactaacaa aattactgaa actgactcgt ttacttagaa taattggact
     9181 tataggtaaa ttagaaagaa aaattagtag attcttacgg acaaatggcc tgatttatat
     9241 cttatatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     9301 aaaatccttc tcagatagtc tctggtgggc tcttgtgacg gtaactactg ttggttatgg
     9361 tgatgttgtt cctacttcaa tttttggtaa atggttagct gtcttattaa tgcttgtcgg
     9421 tattgggaca ataggaatgt taacgagtac cttgacgaac ttttttgtaa aggataatcc
     9481 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagccaaa gaatattaat
     9541 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     9601 aatatcataa aggtgagaca aaacaaaact tgattcgagg agaaatcaag taagtcttga
     9661 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     9721 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     9781 tgatagggtg ctatttcaac ttcaacctac tataatacag aaaaaaaaca actccctgat
     9841 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     9901 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     9961 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
    10021 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
    10081 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
    10141 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
    10201 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
    10261 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
    10321 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
    10381 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
    10441 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
    10501 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
    10561 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
    10621 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
    10681 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
    10741 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
    10801 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
    10861 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
    10921 aaaactttgt cacgaatatg ccttatagtt ctcgatgtaa acgttttagt ggtttagagg
    10981 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
    11041 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
    11101 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
    11161 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
    11221 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
    11281 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
    11341 atgcttgtag atggtcacgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
    11401 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
    11461 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
    11521 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
    11581 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
    11641 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
    11701 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
    11761 gccctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
    11821 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
    11881 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
    11941 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
    12001 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
    12061 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
    12121 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
    12181 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
    12241 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
    12301 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
    12361 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
    12421 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
    12481 aagcgccgta cagagttgat gattggacag gtcttgagtc tcgaggatga ggacttgatt
    12541 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
    12601 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
    12661 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
    12721 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
    12781 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
    12841 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
    12901 attgtgaaga gaaccagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
    12961 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
    13021 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
    13081 atgagtcgta tcgccactgg tgtaaaaggt gttaaccttc gtgaaggaga cacagttgtt
    13141 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
    13201 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
    13261 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
    13321 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
    13381 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
    13441 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
    13501 gaaggtgaag aataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
    13561 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
    13621 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
    13681 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
    13741 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
    13801 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
    13861 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
    13921 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
    13981 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
    14041 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
    14101 gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
    14161 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct gatgaaattc
    14221 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
    14281 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggacga
    14341 atcg
//
LOCUS       DAVBOU010000052        14208 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBOU010000052 DAVBOU010000000
VERSION     DAVBOU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.052"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ879_001770"
     CDS             <1..211
                     /locus_tag="VQ879_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143882.1"
                     /translation="PRKSSKLKPLTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(526..2217)
                     /locus_tag="VQ879_001771"
     CDS             complement(526..2217)
                     /locus_tag="VQ879_001771"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3143883.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2353..2799
                     /gene="argR"
                     /locus_tag="VQ879_001772"
     CDS             2353..2799
                     /gene="argR"
                     /locus_tag="VQ879_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3143884.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2850..5384
                     /gene="mutS"
                     /locus_tag="VQ879_001773"
     CDS             2850..5384
                     /gene="mutS"
                     /locus_tag="VQ879_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3143885.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5531..7225
                     /gene="patA"
                     /locus_tag="VQ879_001774"
     CDS             5531..7225
                     /gene="patA"
                     /locus_tag="VQ879_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3143886.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7555..7818)
                     /locus_tag="VQ879_001775"
                     /pseudo
     CDS             complement(7555..7818)
                     /locus_tag="VQ879_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8016..9782
                     /gene="patB"
                     /locus_tag="VQ879_001776"
     CDS             8016..9782
                     /gene="patB"
                     /locus_tag="VQ879_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3143887.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMCNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9921..10610
                     /locus_tag="VQ879_001777"
     CDS             9921..10610
                     /locus_tag="VQ879_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3143888.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            10614..10793
                     /locus_tag="VQ879_001778"
     CDS             10614..10793
                     /locus_tag="VQ879_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143889.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10780..12129
                     /locus_tag="VQ879_001779"
     CDS             10780..12129
                     /locus_tag="VQ879_001779"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3143890.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12253..13713
                     /locus_tag="VQ879_001780"
     CDS             12253..13713
                     /locus_tag="VQ879_001780"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3143891.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13727..14161
                     /locus_tag="VQ879_001781"
     CDS             13727..14161
                     /locus_tag="VQ879_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3143892.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4160 a         2749 c         3194 g         4105 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccact aacagttgaa gatcaagcct ataaccatgc
       61 gctatccaag gagagaagca aggtcgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgattgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctatta tttggttagg
      241 tgaattagtg aagcgtttag gcaagtgtct ctggttacga cgtcatggcc tctaaatcga
      301 ttatatttag gggtcatgac tagtgaagca gttagctagt tcgcatataa gcggctagcg
      361 tctaacaatt aggaacttta gttccaataa ctttaagatt acgacgtttt aggacataaa
      421 tcgatcatat ttatgtccta aaactagtga agcgcctagc caaagtccga ataggatttg
      481 gcgttagtta cttagattgc tttgcaatca agtaactttg gcgatttaca tcttctctgg
      541 cgcttctact ccaagcaagc gaagggcttc ttttagaacg actgcggttg cgtagctgag
      601 ggctagacgg ctgtcgcgtt ctgggctttc atccaagata cgtgtatgtg catagtattt
      661 gttaaaggat tgagctaggc taattgcaaa tttagcaatg atagaaggtt caaagttatc
      721 tgccgcacgg ttgataatac gtgggaagtc ttgaatgagt ttaatgattt cccagctttc
      781 agtatcattc aagctatagt tgccagctgt ttctggtttg aaatcggctt tgcgtaagat
      841 agattggata cgagcgtagg catattgaac gtaaggtcca gtttcaccct cgaaggatac
      901 catagcttct aggtcgaagt cgtatccatt tgtacggtcg gttttgaggt catagaattt
      961 aatggctcca accccaacag catgtgctac ttggtctttg ttttctagtt caggattttt
     1021 agcctcgatt tggaccttgg cacggctaac agcctctgca acagtaggct ctagcaagat
     1081 gacattccct ttacgagtag agagcttctt cccttccttt gtaaccaaac caaaaggaac
     1141 gtgagtaatg tcgtcactcc agtcgtagcc catctcttgc aagacagctt tgagctgttt
     1201 aaagtgggca gattgttctt gaccaacgac atagatagat ttagcaaatt ggtattcgtt
     1261 tttacggtaa agggctgcag ccaagtcacg tgtgatatag agagttgcac catcagactt
     1321 cttgatgagg gctggatgtt caattccata tttctcaaga ttcacaactt gggcaccttc
     1381 tgattcaaga agtagtcctt tttcagaaag aatgtctaca actgcatcca tcttatcatt
     1441 gtagaaggct tctccgttat agctgtcaaa ttcaaccttc aattcattgt aaaggcggtt
     1501 aaattccact aaactttcat cgcggaacca ttgccaaaga gcgagagctt cctcatctcc
     1561 attttcaagt ttacggaacc attcgcgcgc ttcttcatcc aagctagggt cattttcagc
     1621 ttcagcgttg atgcggacat agagtttaag gagttcatcg attggatgag cttttacagc
     1681 ttcttcgtcg ccccattttt tgtaggcaac aatcaacatc ccaaattgtt taccccagtc
     1741 tcccaaatgg ttgaccttga ccgtttgata accgattttt tggaaaatat gtgacaagct
     1801 atctccgata acagttgaac gcaggtggcc aatagaaaat ggtttagcga tattcggact
     1861 agacatgtcg ataacaacat tttcttgttt gccaatattt tggtcagcat agtgttcttt
     1921 ttcagttgta acagcttgca atacttgagc agaaatggca gatttatcaa ggaaaaagtt
     1981 aacgtaaggt cctgttgcga caactttttc aaaggcttgg ctgttcattt tttcagccag
     2041 ttcagccgca atcatttgtg gtgctttacg ttcgactttg gcaagagaaa aagcagggaa
     2101 agcgatgtca cccatttctg agtttttagg ggtttccagt aactttaaaa tagcctcttg
     2161 gtccaggcta tcaatgatgc tagccaattc gctagcaatc aattcttttg tattcattaa
     2221 gagctccttt ttggactttt ctactatttt aacacaattt taaagaaaga agaaaaaatt
     2281 tttgaaatct cttgtttttt tggtataata tggttataaa tatagttata aatatgcacg
     2341 caagaggatt ttatgagaaa aagagatcgt catcagttaa taaaaaaaat gattactgag
     2401 gagaaattaa gtacacaaaa agaaattcaa gatcggttgg aggcgcacaa tgtttgtgtg
     2461 acgcagacaa ccttgtctcg tgatttgcgc gaaatcggct tgaccaaggt caagaaaaat
     2521 gatatggtgt attatgtact agtaaatgag acagaaaaga ttgatttggt ggaatttttg
     2581 tctcatcatt tagaaggtgt tgcaagagca gagtttacct tggtgcttca taccaaattg
     2641 ggagaagcct ctgttttggc aaatattgta gatgtaaaca aggataaatg gattttagga
     2701 acagttgctg gtgccaatac cttattggtt atttgtcgag atcagcacgt tgccaaactc
     2761 atggaagatc gtttgctaga tttgatgaaa gataagtaag gtcttgggag ttgctctcaa
     2821 gacttatttt tgaaaaggag agacagaaaa tggcgataga aaagctatca cccggcatgc
     2881 aacagtatgt ggatattaaa aagcaatatc cagatgcttt tttgctcttt cggatgggtg
     2941 atttttatga attattttat gaggatgcgg tcaatgctgc gcagattctg gaaatttcct
     3001 taacgagtcg caacaagaat gccgacaatc cgatccctat ggcgggtgtt ccctatcatt
     3061 ctgcccaaca gtatatcgat gtcttgattg agcagggtta taaggtggct atcgcagagc
     3121 agatggaaga tcctaaacaa gcagttgggg ttgttaaacg agaggttgtt caggtcatta
     3181 cgccagggac agtggtcgat agcagtaagc cggacagtca gaataatttt ttggtttcca
     3241 tagaccgcga aggcaatcaa tttggcctag cttatatgga tttggtgacg ggtgactttt
     3301 atgtgacagg tcttttggat ttcacgctgg tttgtgggga aatccgtaac ctcaaggctc
     3361 gagaagtggt gttgggttat gacttgtctg aggaagaaga acaaatcctc agccgccaga
     3421 tgaatctggt actctcttat gaaaaagaaa gctttgaaga ccttcattta ttggatttgc
     3481 gattggcaac ggtggagcaa acggcatcta gtaagctgct ccagtatgtt catcggactc
     3541 agatgaggga attgaaccac ctcaaacctg ttatccgcta cgaaattaag gatttcttgc
     3601 agatggatta tgcgaccaag gctagtctgg atttggttga gaatgctcgc tcaggtaaga
     3661 aacaaggcag tcttttctgg cttttggatg aaaccaaaac ggctatgggg atgcgtctct
     3721 tgcgttcttg gattcatcgc cccttgattg ataaggaacg aatcgtccaa cgtcaagaag
     3781 tagtgcaggt ctttctcgac catttctttg agcgtagtga cttgacagac agtctcaagg
     3841 gtgtttatga cattgagcgc ttggctagtc gtgtttcttt tggcaaaacc aatccaaagg
     3901 atctcttgca gttggcgact accttgtcta gtgtgccacg gattcgtgcg attttagaag
     3961 ggatggagca acctactcta gcctatctca tcgcacaact ggatgcaatc cctgagttgg
     4021 agagtttgat tagcgcagcg attgctcctg aagctcctca tgtgattaca gatgggggaa
     4081 ttatccggac tggatttgat gagactttag acaagtatcg ttgcgttctc agagaaggga
     4141 ctagctggat tgctgagatt gaggctaagg agcgagaaaa ctctggtatc agcacgctca
     4201 agattgacta caataaaaag gatggctact attttcatgt gaccaattcg caactgggaa
     4261 atgtgccagc ccactttttc cgcaaggcga cgctgaaaaa ctcagaacgc tttggaaccg
     4321 aagaattagc ccgtatcgag ggagatatgc ttgaggcgcg tgagaagtca gccaacctcg
     4381 aatacgaaat atttatgcgc attcgtgaag aggtcggcaa gtacatccag cgtttacaag
     4441 ctctagccca aggaattgcg acggttgatg tcttacagag tctggcggtt gtggctgaaa
     4501 cccagcattt gattcgacct gagtttggtg acgattcaca aattgatatc cggaaagggc
     4561 gccatgctgt cgttgaaaag gttatggggg ctcagaccta tattccaaat acgattcaga
     4621 tggcagaaga taccagtatt caactggtta cagggccaaa catgagtggg aagtctacct
     4681 atatgcgtca gttagccatg acggcggtta tggcccagct gggttcctat gttcctgctg
     4741 aaagcgccca tttaccgatt tttgatgcga tttttacccg tatcggagca gcagatgact
     4801 tggtttcggg tcagtcaacc ttcatggtgg agatgatgga ggccaataat gccatttcgc
     4861 atgcgaccaa gaactctctc attctctttg atgaattggg gcgtggaact gcaacttatg
     4921 acgggatggc tcttgctcag tccatcatcg aatatatcca tgagcacatc ggagctaaga
     4981 ccctctttgc gacccactac catgagttga ctagtctgga gtctagttta caacacttgg
     5041 tcaatgtcca cgtggcaact ttggagcagg atgggcaggt caccttcctt cacaagattg
     5101 aaccgggacc agctgataaa tcctacggta tccatgttgc caagattgct ggcttgccag
     5161 cagacctttt agcaagggcg gataagattt tgactcagct agagaatcaa ggaacagaga
     5221 gtcctcctcc catgagacaa actagtgctg tcactgaaca gatttcactc tttgataggg
     5281 cagaagagca tcctatccta gcagaattag ctaaactgga tgtgtataat atgacaccta
     5341 tgcaggttat gaatgtctta gtagagttaa aacagaaact ataaaaccaa gactcactag
     5401 ttaatctagc tgtatcaagg agacttcttt gacaattctc cacttttttg ctagaataac
     5461 atcacacaaa cagaatgaaa aggagctgac gcattgtcgc tcccttttgt ctatttttta
     5521 aggagaaagt atgctgattc agaaaataaa aacctacaag tggcaggccc tggcttcgct
     5581 cctgatgaca ggtttgatgg ttgctagttc acttctgcaa ccgcgttatc tgcaggaagt
     5641 cttaggcgcc ctccttactg ggaaatatga agctatttat agtatcgggg cttggttgat
     5701 tggtgtggcc gtagtcggtc tagttgctgg tggactcaat gttgtcctcg cagcctatat
     5761 tgcccaagga gtttcatccg accttcggga ggatgccttc cgtaaaattc aaaccttttc
     5821 ttatgctgat attgaacaat ttaatgcggg aaatctagtc gttcgaatga caaatgatat
     5881 caaccagatt cagaacgttg tcatgatgac cttccagatt cttttcagac ttcccctctt
     5941 gttcatcggt tcgtttatcc tagcggttca aaccttacct tctctgtggt gggtgattgt
     6001 tctcatggta gtcttgattt ttggtttgac tgctgtcatg atgggaatga tggggcctcg
     6061 ttttgccaag tttcaaaccc ttcttgagcg catcaatgcc attgccaagg aaaatttacg
     6121 tggcgttcgt gtggtcaagt cctttgtcca agaaaaagag caatttgcta agtttacaga
     6181 ggtctcagac gagcttcttg gtcaaaacct ttacattggt tatgcctttt cagtagtgga
     6241 accctttatg atgttggttg gttacggggc ggtcttcctc tctatttggc tggtcgcggg
     6301 aatggttcag tcggatccgt ctgttgttgg ttccatcgct tcttttgtta attacctaag
     6361 ccagattatc tttaccattg ttatggttgg atttttggga aattctgtca gccgtgccat
     6421 gatttccatg cgtcgtattc gagaaattct tgacgcagag ccagctatga ccttcaagga
     6481 tatcccagat gaagagttgg ttggaagcct tagctttgaa aatgtgacct ttacctatcc
     6541 aatggacaat gaaccgatgc tgaaagatgt gagctttact attgaacctg gtcaaatggt
     6601 tggtgtagtt ggagcgactg gtgcaggaaa gtcaaccttg gctcaattga ttccacgtct
     6661 ctttgatcca cagaacgggg ccattaaaat cggtggcaag gatattcgag aagtgagtga
     6721 aggaaccctg cgtaaaacag tttccatcgt tctccaacgt gccattcttt ttagtggaac
     6781 gattgcagat aacttgagac aggggaaggg aaatgctact ctatttgaaa tggagcgcgc
     6841 agccaatatt gcccaggcta gtgaattcat tcatcgtatg gagaaaacct ttgaaagtcc
     6901 agttgaagaa cggggaacca atttctctgg tggacaaaaa caaaggatgt cgattgcgcg
     6961 tgggattgtc agcaatccac gtattctgat ttttgacgat tcgacctcag ccttggatgc
     7021 caaatcagag cgcttggtgc aagaagcttt gaataaggac ttgaagggga cgacaaccat
     7081 tattattgct caaaaaatta gctcggttgt ccatgcagac aagatcttgg ttctaaatca
     7141 aggacgattg attggtcaag gcacgcatgc agacttggtt gccaacaatg ccgtttaccg
     7201 tgaaatctat gaaacacaga aatgaaagac aaactataag aaaagtcaat agttttatct
     7261 aaattatttc ttatttcaat ttgatgattt ggcgatgatt ttagagcacg gcaaaaagcc
     7321 cttgaaaaag tccatttttt caaaggtaat cctgtgttga tttcagaaat tacatcactt
     7381 tttgttcgtc aaatggcagc tcttttttag gatataaaac agggttcgga taagtttttt
     7441 tgtaaggtgg atgatggcta cattgtaatg ttttccttat tctaacttag tcttaagata
     7501 ggccttaaaa gcaggtgaaa agcgagggca tgctttggca gcttgtatga gtgcctaccg
     7561 cagatgaggg gaaccccgtt tgatcattct tccagctaaa tcaatctgat ctgactgata
     7621 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
     7681 attttgaatc tcggctaaaa tgaccgcccc taaacgattc ccaatcccag taaccgtcgt
     7741 gatgatcgag ttgaactcag ccatcaagtc attgacacat gtttccgcct tgtcaatgag
     7801 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtttatgcg ttatcaaact
     7861 catgaccaat tgaaacaaaa agctgtggtt agatcctttc ggaaattgtc aagcgattgg
     7921 aggaaatgaa ctaatccaca gcggcttatt ccaagtatac cacttgggct ttggcagtag
     7981 ctaactgcgc taaatataat ataaggagga gtaaaatgaa gacagttcaa tttttttggc
     8041 attattttaa ggtttacaag ttctcatttg tagttgtcat cctgatgatt gttctggcga
     8101 cttttgccca agccctcttt ccagtctttt ctggacaagc ggtgacgcag ctagccaatt
     8161 tagttcaagc ttatcaaaat ggcaatccag aacttgtatg gcaaagccta tcaggaatca
     8221 tggtcaatct tggcctgctg gttttggttc tatttatctc tagtgtaata tacatgtgtc
     8281 tcatgacgcg cgtgattgca gaatcgacca acgagatgcg caaaggcctc tttggtaagc
     8341 ttgctcagtt gacggtttct ttctttgacc gtcgacaaga tggcgatatc ctgtctcatt
     8401 ttaccagtga tttggataat atcctccaag cctttaacga aagcttgatt caggtcatgt
     8461 gcaatattgt tttatacatt ggtctgattc ttgtcatgtt ttcgagaaat gtgacgctgg
     8521 ctctcatcac cattgccagc accccattgg ctttccttat gctgattttc atcgtgaaaa
     8581 tggcacgcaa atacaccaac ctccagcaga aagaggtagg gaagctcaac gcctatatgg
     8641 atgagagcat ctcaggccaa aaagccgtga ttgtgcaagg aattcaagag gatatgatgg
     8701 caggatttct tgaacaaaat gagcgcgtgc gcaaggcaac ctttaaagga agaatgttct
     8761 caggaattct tttccctgtc atgaatggga tgagcctgat taatacagcc atcgtcatct
     8821 ttgctggttc ggctgtactt ttgaatgata agtctattga aacaagtaca gccctaggtt
     8881 tgattgttat gtttgcacaa ttttcacagc agtactacca gcctattatc caagttgcag
     8941 cgagttgggg aagccttcag ttggccttta ctggagctga acgaattcag gaaatgtttg
     9001 atgcagagga ggaaatccga cctgaaaagg ctccaacctt cactaagttg caagaaagtg
     9061 ttgaaatcag tcatatcgat ttttcatact tgcctgataa acctattttg aaagatgtca
     9121 gcatttctgc ccctaaaggc cagatgacag cagttgttgg gccgacaggt tcaggaaaaa
     9181 cgactattat gaacctcatc aatcgctttt atgatgttga tgctggtggt atttattttg
     9241 atggtaaaga cattcgtggc tatgacttag atagtcttag aagcaaggtg ggaattgtat
     9301 tgcaagattc ggtcttgttt agcggaacga ttcgagacaa tatccgattt ggtgtgccag
     9361 atgctagtca ggaaatggtt gaggtagcag caaaagcaac ccacattcac gactatatcg
     9421 aaagtttgcc tgataagtac gatactctta ttgatgatga ccagagcatc ttttcaacag
     9481 ggcagaagca attgatttca atcgctcgaa ccctgatgac agatccagaa gttctcattc
     9541 tcgatgaagc aacttcaaac gtagatacgg tgacagaaag caagattcag catgccatgg
     9601 aggtggttgt agcaggtaga actagtttcg tcattgccca ccgcttgaaa accattctca
     9661 atgcagatca gattattgtc cttaaagatg gagaagtcat tgaacgtggt aaccaccatg
     9721 aacttttgaa gctaggtggc ttttattcag aactctatca caatcaattt gttttcgaat
     9781 gagaaagaag ttgtcctatg tgggcagctt tttcttgtcc ataaaaaatg tttatcacag
     9841 ccttaaaaaa aacatattag acgaaagtca ttttgagtga tatgatagga ctatcgttag
     9901 cattcgaaag gagaggcatc atggctagaa cggttgtagg agttgctgca aatctatgtc
     9961 ccgtagacgc agaaggcaaa atcattcatt catctgtatc ttgtagattc gcagagatca
    10021 ttcgtcaagt cggtggtctc cctttagtca ttcctgttgg tgatgagtca gttgtacgtg
    10081 attatgtgga aatgattgac aaactcattt tgacaggagg ccaaaatgtt catcctcagt
    10141 tttatggaga gaaaaagacc gtcgagagcg atgattacaa tctggtccgt gacgaatttg
    10201 aattggcact cttgaaggaa gcgcttcgtc agaataaacc aattatggca atctgtcgcg
    10261 gtgtccaact tgtcaatgtt gcctttggtg gaaccctcaa tcaagaaatc gaaggtcact
    10321 ggcaaggact acctttcggg acatctcact ctattgagac agtagaagga agcgtggtgg
    10381 ctaagctatt tgggaaagaa agtcaggtca attcagtcca tcgtcaaagc attaaagatt
    10441 tggcacccaa tttccgtgta actgctattg attcaagaga ccaaactatt gaagcgattg
    10501 agtctatcga cgagcaccgc attatcggtt tacagtggca tccagagttt ctggttaatg
    10561 aagaagatgg caatttagaa ttatttgagt atttattgaa tgaactgtaa cgattggaac
    10621 atctggtcgt tctttctttt attttttcaa aatttttaga atgtggtatt ttacgcaaac
    10681 gtttgaattc tgataaaaat tggagaaatt cgacaaaaaa acttgaaaaa aacgaaggta
    10741 agcgttatga tagaaaagaa gaaatattgg aggaagaaca tgtcacatat taaatttgat
    10801 tattcaaaag ttttagacaa atttgttgca ccacatgaag tggaatacat gcaatcacaa
    10861 gtaacagcag cagatgaatt gatccgtaaa ggaactggtg ctggtagcga cttcttggga
    10921 tggttggacc ttcctgaaaa atacgaccgc gaagaatttg accgcatctt gaaagctgct
    10981 gagcaaatca agtcagacag cgatgttttg gttgtgatcg gtattggtgg atcttacctt
    11041 ggtgcaaaag cagcaatcga cttcttgaat caccattttg ctaacttgca aacaaaagaa
    11101 gaacgcaaag ctccacaaat cctttacgca ggaaactcaa tctcatctac ttaccttgct
    11161 gacttggtag agtatgttgc agacaaagac ttctcagtaa acgtaatttc taaatcaggt
    11221 acaacaactg aaccagcgat tgctttccgt gtctttaaag aactcttggt taagaaatac
    11281 ggtcaagaag aagctaacaa acgtatctat gcaacaactg accgccaaaa gggtgctgtt
    11341 aaggttgaag cagacgctaa cggttgggaa acatttgttg ttccagatga tatcggtgga
    11401 cgcttctcag tattgacagc cgttggtttg cttccaatcg cagcatcagg agctgacatc
    11461 aaagctctta tggaaggtgc gaatgcagct cgcaaagact acacttcaga caaaatctct
    11521 gaaaacgaag cttaccaata cgcagctgtt cgtaacatcc tttatcgtaa aggctatgca
    11581 actgagatct tggtaaacta tgagccatca cttcaatact tctcagaatg gtggaaacaa
    11641 ttggctggtg aatcagaagg aaaagaccaa aaaggtatct acccaacttc agccaacttc
    11701 tcaactgact tgcactcact tggtcaattt atccaagaag gaactcgtat catgtttgaa
    11761 acagttgtcc gtgttgacaa acctcgtaaa aacgtgctta ttcctacttt ggaagaagac
    11821 cttgacggac ttggttacct tcaaggaaaa gacgttgact ttgtaaacaa aaaagcaact
    11881 gacggtgttc ttcttgccca cacagatggt gatgtaccaa acatgtatgt gactcttcca
    11941 gagcaagacg ctttcactct tggttacact atctacttct tcgaattggc aattgccctt
    12001 tcaggttact tgaatgctat caacccattt gaccaaccag gtgttgaagc ttataaacgt
    12061 aacatgtttg cccttcttgg aaaaccagga tttgaagaat tgagcaaaga acttaacgca
    12121 cgtctataat agaagaaaag agtggtttac ccactctttt tactctcttt atccatagaa
    12181 attggactca gtcaagactt gtgatataat atagaaagca aaaaggcaga tgcctagata
    12241 ataggagaaa ctatgtcaaa agatatccgc gtacgttacg caccaagtcc aacaggacta
    12301 ctacacatcg gaaatgctcg tacagcattg tttaattact tgtatgcgcg ccatcatggt
    12361 ggaacatttc tcatccgtat cgaagatact gaccgtaaac gccatgtcga ggatggtgaa
    12421 cgttcacaac ttgaaaacct tcgctggtta ggcatggatt gggatgaaag tccagaatca
    12481 catgagaatt atcgccagtc tgagcgttta gacttgtatc aaaaatacat tgaccaacta
    12541 ttagctgaag gaaaagccta taaatcttac gttacagaag aagagttggc agctgaacgc
    12601 gaacgccaag aagtagctgg cgaaacacca cgctacatca atgaatacct tggtatgagt
    12661 gaagaagaaa aagcagctta catcgcagaa cgtgaagcag cagggatcat cccaactgtt
    12721 cgtttggctg tcaatgagtc aggtatctac aagtggcatg atatggtcaa aggcgatatc
    12781 gaatttgaag gtggcaatat cggtggtgac tgggttatcc aaaagaaaga cggttaccca
    12841 acttacaact ttgccgttgc catcgatgac cacgatatgc aaatctctca tgttatccgt
    12901 ggagatgacc atattgctaa tacaccaaaa cagcttatgg tctatgaatc tcttggttgg
    12961 gaagctccag agttcggtca catgaccttg attatcaact ctgagactgg taagaagtta
    13021 tctaaacgtg atactaatac acttcaattt atcgaagatt accgaaagaa aggttacctt
    13081 ccagaagcag tctttaactt tattgctctt cttggttgga acccaggtgg tgaagatgag
    13141 attttctctc gtgaagaact cattaaactt tttgatgaaa accgcctcag caagtcacca
    13201 gcagcctttg atcagaaaaa actagactgg atgagcaatg attatatcaa gaatgcagac
    13261 cttgaaacca tctttgaaat ggcaaaacca ttcttagagg aagcaggccg tttgactgac
    13321 aaggctgaaa aattagttga gctctataaa ccacaaatga aatcagtaga tgagattatc
    13381 ccattgacag atcttttctt ctcagatttc ccagaattga cagaagcaga gcgcgaagtc
    13441 atgacgggtg aaacagttcc aacagttctt gaagcattca aagcaaaact tgaagcgatg
    13501 acagatgata aatttgtgac agaaaatatc ttcccacaaa ttaaagcagt tcaaaaagaa
    13561 acaggtatta aagggaaaaa tcttttcatg cctattcgta tcgcagtttc aggcgaaatg
    13621 catgggccag aattaccaga tacaattttc ttgcttggac gtgaaaaatc aattcagcat
    13681 atcgaaaaca tgctaaaaga aatctctaaa taaagaggat acaataatgg acatctggga
    13741 aaagatgtac gaagaagcac agaaactata caatccacat gaagtatcag actttgttta
    13801 tgccaatcat gttgtagctg cagtagaagc agaagatgga caaatattta caggattctg
    13861 tatggaggga acctgtggtg ttttccatct ctgcgcagaa cgggcggccc tcttcaatat
    13921 gtaccaattt tcaggacaaa ctaaggttaa gaaagtatta gcctttcgag acaaaccacc
    13981 ttatggtgga agttcagcca tgccttgcgg tgcttgtaga gaattccttt tagagcttaa
    14041 tgctgaaaat aaagatgcag aattcatgat ggactataat ataagaaaaa cagttaaagt
    14101 cgcagaacta atcccttatt ggtggggaga agaacgtgct tctaagttta atgagcgata
    14161 gaagagtcag tataattttg gctcttttta ctataagttg aaaaaata
//
LOCUS       DAVBOU010000053        13176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBOU010000053 DAVBOU010000000
VERSION     DAVBOU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.053"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            276..890
                     /locus_tag="VQ879_001782"
     CDS             276..890
                     /locus_tag="VQ879_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3143893.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            994..1824
                     /locus_tag="VQ879_001783"
     CDS             994..1824
                     /locus_tag="VQ879_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3143894.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1978..2832
                     /locus_tag="VQ879_001784"
     CDS             1978..2832
                     /locus_tag="VQ879_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3143895.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2932..4305
                     /locus_tag="VQ879_001785"
     CDS             2932..4305
                     /locus_tag="VQ879_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3143896.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4298..5359
                     /locus_tag="VQ879_001786"
     CDS             4298..5359
                     /locus_tag="VQ879_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3143897.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5361..6053
                     /locus_tag="VQ879_001787"
     CDS             5361..6053
                     /locus_tag="VQ879_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143898.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6083..6652)
                     /locus_tag="VQ879_001788"
     CDS             complement(6083..6652)
                     /locus_tag="VQ879_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3143899.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6787..7401
                     /locus_tag="VQ879_001789"
     CDS             6787..7401
                     /locus_tag="VQ879_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3143900.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7403..9049
                     /locus_tag="VQ879_001790"
     CDS             7403..9049
                     /locus_tag="VQ879_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3143901.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9061..10347
                     /locus_tag="VQ879_001791"
     CDS             9061..10347
                     /locus_tag="VQ879_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3143902.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10399..10932
                     /locus_tag="VQ879_001792"
     CDS             10399..10932
                     /locus_tag="VQ879_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143903.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ879_001793"
     CDS             11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ879_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3143904.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11773..13035)
                     /locus_tag="VQ879_001794"
     CDS             complement(11773..13035)
                     /locus_tag="VQ879_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3143905.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3901 a         2452 c         3007 g         3816 t
ORIGIN      
        1 tatcttattt caatctgcta tataatagtc catgctatgg ctggattctt ttcagtctac
       61 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta gtacggttac
      121 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
      181 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
      241 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
      301 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
      361 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
      421 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
      481 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
      541 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
      601 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
      661 tggggacagt agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct
      721 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
      781 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
      841 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
      901 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
      961 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     1021 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     1081 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     1141 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
     1201 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
     1261 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
     1321 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
     1381 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
     1441 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
     1501 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
     1561 gatggacaat ttgactataa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
     1621 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
     1681 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
     1741 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
     1801 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
     1861 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
     1921 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
     1981 aaaatcaaaa aatggcttgg tctagcagcc cttgctacag tcgcaggttt ggctcttgca
     2041 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
     2101 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
     2161 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
     2221 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaataa ctggaacaaa
     2281 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
     2341 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
     2401 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
     2461 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
     2521 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
     2581 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
     2641 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
     2701 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
     2761 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
     2821 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
     2881 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatgtttttt
     2941 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagccca gcattatttt
     3001 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
     3061 gaagtcgcaa actatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
     3121 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
     3181 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
     3241 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
     3301 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
     3361 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
     3421 ctagataagt atttggaaaa gcatgcagac aaactctgtg gggcggattt gttggtctgg
     3481 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taagggaatt
     3541 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
     3601 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
     3661 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
     3721 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
     3781 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
     3841 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
     3901 cctgcagaag ccagtgcaaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
     3961 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
     4021 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
     4081 atcgagttgg ccaagaaatt ctatccacag ggtgtttcag tcttgccgac gacagcgggg
     4141 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
     4201 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
     4261 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
     4321 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt
     4381 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcaggaaa
     4441 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
     4501 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
     4561 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
     4621 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
     4681 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
     4741 attatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
     4801 aatcttgatt tcagacgagt caacttctgc ccttgaccct aagacaacca agcagatttt
     4861 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
     4921 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
     4981 tgaagagggt agtgtgcttg aaatcttctc aaaccctaaa caacctttga ctcaagactt
     5041 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
     5101 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
     5161 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
     5221 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggttt tgtcaggtga
     5281 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
     5341 attgaaggga gtacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
     5401 agatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
     5461 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
     5521 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
     5581 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
     5641 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
     5701 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
     5761 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
     5821 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
     5881 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
     5941 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
     6001 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
     6061 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
     6121 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
     6181 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
     6241 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
     6301 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
     6361 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
     6421 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
     6481 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
     6541 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
     6601 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
     6661 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
     6721 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
     6781 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
     6841 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
     6901 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
     6961 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
     7021 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
     7081 cagaccattg ttcatttgat tgcgaccctt ttgaatgtct tagtagttgc cctgatcttt
     7141 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
     7201 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
     7261 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
     7321 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
     7381 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
     7441 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
     7501 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
     7561 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
     7621 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
     7681 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
     7741 cctctatgtt cgaaatgatt ttgtaactgg agtggccatt gcttttcaag attacaagga
     7801 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
     7861 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
     7921 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
     7981 taatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
     8041 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
     8101 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
     8161 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
     8221 tgctaattac caaaagcagg tagtggattt agtagaatcc attcaagtca ttgctcaagg
     8281 cgaagagggt cgtcggattg acatttccga gaaagatcag gaattactcc taatcgcgga
     8341 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
     8401 gcttagtcaa aaagatgcta atatgcgagc cttgcaggcg caaatcaatc ctcattttat
     8461 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
     8521 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
     8581 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
     8641 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
     8701 taagttcacc ttgcaaccgc tggtagaaaa ttatttcgcg catggtgttg accacaggcg
     8761 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
     8821 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
     8881 tcagagaaat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcgggattgt
     8941 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta ctatagagtc
     9001 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
     9061 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
     9121 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
     9181 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
     9241 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
     9301 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
     9361 gactatttgg tcaaacctgt tgataaggta gagctgggaa atctgctgga gaagattgca
     9421 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
     9481 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
     9541 caaggttcct tcaccattcc ctactatgtc ttgggtcaag cctggcagat tttcatttct
     9601 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacatttt
     9661 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
     9721 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
     9781 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcga
     9841 attccgatta ctaaacagct ttttatccag tttgtcatgg atgtcttcca tttatttgaa
     9901 catctcaaag ctgatgatat gacggacatt gtcaaaacca ttcatgctat tcaatccttc
     9961 gatgaattgg tttcttatat caaggaaact ctgatcagct ttttcggtca ataccgtatg
    10021 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    10081 ctcaaggata tcagtaaggc cctctttatc aatcctgtct atctagggca gttgattaag
    10141 cgtgaaaccg attcgacctt tgcagagtta ctaaacaaac aacgtattaa ggctgcccag
    10201 cagctcttgc tttcaaccag tgacagtatc gaagatattt gttatgctgt tggttacagt
    10261 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    10321 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    10381 ttatcaggag gttctatcat gaaaaagaaa ccaatttatc tatgggtctt gctaatcttg
    10441 tctgccctta tttcagttcc gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa
    10501 gcccttcgtg ttgctcagaa acaagttgca ggggtcaatg ctcagcaatt agaagaccag
    10561 cttaattata cctatagagt agcagaagca tctcattcta tttttaatgt tgctttgatt
    10621 gtgctatcta ctattttagt ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa
    10681 tatgcaaact atacttacgt tggctatgtt ttgttagcta ttattggttc gatttatggc
    10741 tatgttggtt tacaagacgc tgtgcagttg gttcaagatg agagcatgcg tttgacagtg
    10801 agtattggtt caaaagctgt tagcattttc tatatcgtca tcaatgttct cttcctagcc
    10861 cttgtcttct ataagatgtg gcgacaacag aaagccttgg cagaagaaga ggaaacagaa
    10921 gagcttgcct aagtattgac aaaaaagaac tatcaagata caatcttggt agttattttt
    10981 tgattataga taaaatcatg gaggtacata tgaagacaat ttctttagtt tatattagtt
    11041 tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca
    11101 aagggattga ggttcaaaag attcatatca aggatttggt caaggaaggc aaaaatttct
    11161 atgaaatgga ccatctctat gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg
    11221 tggataacgg agatgttgag attttgacaa caccggtggg agattttatt gcctatggta
    11281 acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat
    11341 actgcctaac agccaagcaa tacagtcaac gctttggctt ccctgtattg gctgactttg
    11401 aaatgcgagg catgctggaa gatatcaaac atgtcgcagc tattatcgca gatttgtatg
    11461 agttggaaaa ggagaattaa tactcaatga aaatcaaaga gcaaactagg aagctagtcg
    11521 caggttgctc aaagcacagc tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    11581 ctcgaatagt ataaagttct tataagaggt ggttgaagtt gttcaactgt tttttgagta
    11641 taaacagtct ttaagaacgt aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat
    11701 gctttttatc atagaaatat ttgctgaatt ttctcttgaa atgaaacctt atcttcatct
    11761 cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg tagataaaga agatggcgaa
    11821 gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg agccaagaag gaagattttt
    11881 gttttcacgc gttaccaagg cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga
    11941 tccaatcatg gcaaagcgga gcatggttga aacctgacca gcgaagaact tgataatgac
    12001 gataccgatg atagcagtga tggtcatcca gatgttcaaa gatttacgat tgtcctcttt
    12061 ttgactgatt agcagtcgga gagattcctg attaacgcga gaatagccat cgataacagt
    12121 tataactgtt ccaaagatac agaggaaggc aataaaggta atcaagtaac gggaccattc
    12181 gccaagaaca gaggcataca tgcccacgaa ttgagagatg tatttggctg aagcagcttc
    12241 aaccgcctgc cctgtaggat actgaatcag tgctcccagt gccacaaaga agacggctag
    12301 gatagctgtt ccaatataac cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt
    12361 gacggtcttt ctcttttcag ctgaccaaag tgaattgata gctgaaattt caataggagc
    12421 cggcatccat cctaggaggg agacgatgaa gggcagagct gccatttgcc aaggtgtctt
    12481 ctcgacaaaa tcagaactgt attctggatg cttgaccgct gctatgataa ctgccagaac
    12541 agtcgcaatg gttaaggcag acataatcca tttgaccatg ccgtctaaaa gtttgtagcc
    12601 tccaaagagt agcatagccc aaatgattgc aacgagaatg agggaccact gagtaatgct
    12661 aagtccaatc attgggaagg cactggcgat gatagctgag cacagaatgg caacaccagc
    12721 cgtgttgacc atagccgaaa agacattgag gataaagaaa atccagagat agagttttcc
    12781 tttttcggca taaccttcaa ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa
    12841 acggaaaaat ggatatttaa agacattggc taagatgact aagagaagta gagaccaacc
    12901 gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa cctccaacag cggcagttgc
    12961 cattaggatt ccaggtccca ttgcttttag cttgcttgcc caggttgatt gatttaagga
    13021 aatagcttgc gacatgataa atactccttt ttgaattttc agaataatct gtatatgtaa
    13081 tctatattct acaaaaaatt ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat
    13141 ttacaaagaa aatctgaaat aactgttatg atatag
//
LOCUS       DAVBOU010000054        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBOU010000054 DAVBOU010000000
VERSION     DAVBOU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.054"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ879_001795"
     CDS             <1..367
                     /locus_tag="VQ879_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3143906.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ879_001796"
     CDS             complement(442..972)
                     /locus_tag="VQ879_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3143907.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ879_001797"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ879_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ879_001798"
     CDS             1984..2661
                     /locus_tag="VQ879_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3143908.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ879_001799"
     CDS             2648..3445
                     /locus_tag="VQ879_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3143909.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ879_001800"
     CDS             3462..4565
                     /locus_tag="VQ879_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3143910.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ879_001801"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ879_001801"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3143911.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ879_001802"
     CDS             5887..6840
                     /locus_tag="VQ879_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3143912.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ879_001803"
     CDS             complement(6902..7108)
                     /locus_tag="VQ879_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3143913.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ879_001804"
     CDS             7160..7636
                     /locus_tag="VQ879_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3143914.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ879_001805"
     CDS             7645..8316
                     /locus_tag="VQ879_001805"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3143915.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ879_001806"
     CDS             8447..8785
                     /locus_tag="VQ879_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3143916.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ879_001807"
     CDS             8788..9417
                     /locus_tag="VQ879_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3143917.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ879_001808"
     CDS             9657..10808
                     /locus_tag="VQ879_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3143918.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ879_001809"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ879_001809"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3143919.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ879_001810"
     CDS             11865..12638
                     /locus_tag="VQ879_001810"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3143920.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ879_001811"
     CDS             12616..13077
                     /locus_tag="VQ879_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3143921.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3763 a         2465 c         2904 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg aattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBOU010000055        13150 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBOU010000055 DAVBOU010000000
VERSION     DAVBOU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13150
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.055"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(278..1501)
                     /locus_tag="VQ879_001812"
     CDS             complement(278..1501)
                     /locus_tag="VQ879_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3143922.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1669..2991
                     /locus_tag="VQ879_001813"
     CDS             1669..2991
                     /locus_tag="VQ879_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3143923.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2993..4879
                     /locus_tag="VQ879_001814"
     CDS             2993..4879
                     /locus_tag="VQ879_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3143924.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            5047..5391
                     /locus_tag="VQ879_001815"
     CDS             5047..5391
                     /locus_tag="VQ879_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3143925.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5401..6813
                     /gene="lacG"
                     /locus_tag="VQ879_001816"
     CDS             5401..6813
                     /gene="lacG"
                     /locus_tag="VQ879_001816"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3143926.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6883..8562
                     /locus_tag="VQ879_001817"
     CDS             6883..8562
                     /locus_tag="VQ879_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3143927.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(8688..10127)
                     /locus_tag="VQ879_001818"
     CDS             complement(8688..10127)
                     /locus_tag="VQ879_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3143928.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ879_001819"
     CDS             complement(10131..11480)
                     /gene="trkA"
                     /locus_tag="VQ879_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3143929.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11668..12516
                     /locus_tag="VQ879_001820"
     CDS             11668..12516
                     /locus_tag="VQ879_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3143930.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12531..13079
                     /locus_tag="VQ879_001821"
     CDS             12531..13079
                     /locus_tag="VQ879_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3143931.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         4027 a         2106 c         2807 g         4210 t
ORIGIN      
        1 gagaattgta aaaacaaaaa tggggatttc atataaagtt tattctagga gtatgtatct
       61 tgaataaaaa ttgttattta agttctgggg gttatgatga atgtttttat aataataaaa
      121 tgcagctaga agaaaagtta ttttaatata aatcactcaa catagagaga aggcggtttc
      181 ctatatggaa gtcgtcttgt tttcatattg tctaaatacg agatatttac tacaggttat
      241 agttgattta aacaggtcta tagatttcta atatatatta aggtgaaata atatcttgta
      301 atacattgct atgctctatg aaaaaagcaa cgatagctaa tgcacaagct cctatacttc
      361 cacgatgttt gttgtaaggt aaaatttcaa tttctatatt acgagtaaag ggaacgaagt
      421 ggagctggtc ttggatttta tccctgactt catgagtgaa aggttgataa ttaagcaatt
      481 gactgttgat atagatttta tcagcaggat tgatgaggag aagatttgca atagaagtgg
      541 ctaataaatt gactccttta tcaatttgtt gacgtaaagc ggagtcgcct aaattataag
      601 ccgttaaaag ggtgtctaaa tgaatgtctt tttcagtctt tacaaggctt tttagtacag
      661 ttagttggga atttttaaat aataattggg cgtgtttgat taaccaagca tccgaaatat
      721 atgtttgtaa acaacctttt tttccgcatt cacaatattg cccattcaat tcgacaatgg
      781 tgtgtccaat ttctccgata taaggatttt tagaggctcc tattttttct tttgtgaaaa
      841 aggaagtgta aatacctaat ccagcgtgta ggaaaataaa gttatcgggg gtattgtgtg
      901 gattaaaaag gtattgtcct atagccatac aatcgatatt attttttaca ataaaaggaa
      961 aattgaatct tttaattaca tttaataaat taaaagattc ccatatgggg ttgtttgtaa
     1021 tgatacttcc ggagtctttg ttataatgtc caggtattga taagccaaat ccaagtaatt
     1081 ttgtttccaa agggacgtac tctatagctg tttttatcat attggtaatg gtggaattga
     1141 tttctgaaat aggataatct tcattcaaaa tttctgtctc gaaaagagtt ttcccttgta
     1201 agtcacatag actgagaaag atacctagga cgtttatttc aatacctcca acaacatacg
     1261 gaatattatc tgtgatagaa atagtttttc tacgtcttcc agatccggaa aactcgctaa
     1321 attcatcacc agtttcgtat atgagggact gttcgcttag ctcttttatg atgttagtcg
     1381 ttgttgctgg agtaagtcct gtttcattaa caatatctgt acgggatgtt gctggatttc
     1441 gatatagaaa ctccagtata gtggctctat tttgtaaaaa ggctgattgt tttgtaatca
     1501 tttgtttcct cctttggttt attttatatt aaacataaga aaaaatcaat taaaattatt
     1561 attctataca aagaaaaaaa tattgtaaaa acaacaaaaa atatattgac aacgctttct
     1621 gttagtggta tatttaattt ataaaaaata aaaaaaggag ttccggtgat gaacaatatt
     1681 ttagcgtttt tagaaacaaa agtcgctccg tttggtgaaa aagttggcaa ccaacggcat
     1741 ttgaaagcta ttcgtgaagg atttatgatg gcaatgcctt tgattttagt cggatcttta
     1801 tttcttattc taatcagttg gcctcaagag gattttacaa attggctgaa tagtgttgga
     1861 ttgctaagta tcttgacaac tatgaatcag tcaacagtag cgattatctc cttggtcgct
     1921 tgtttcggta ttgcctacag gttgtcggaa ggatatggta cagatggtcc gtcggcaggg
     1981 atcatagcct tatccagttt tgtattgatg gcacctcgtt tttcgagtat ggtttatgat
     2041 aaaaatgggg agcaggtcaa gcagttattt ggcggcgcaa taccattttc tagcctgaat
     2101 gcatcttctt tgtttatggc gattactatt ggattggtta cagcagagat ttatcgtatg
     2161 tttatccagc gcggaattac gataaaaatg ccaagtggtg tcccagatgt ggtaagtaaa
     2221 tcattttcag ctcttttacc tggctttact acttttgttt tgtgggctct ggtcttaaaa
     2281 ggtcttgaag cggcaggagt tgcaggaggt ctcaacggac tcctaggtgg aattgttgga
     2341 acaccgctta agttaattgc aggaacgctt ccaggtatga ttctatgtgt tattgtaaac
     2401 tcattctttt ggttctgtgg agttaatggg ggacaagttt taaatgcttt tgtagatcca
     2461 gtttggttac aatttactat agaaaaccaa gaagctgtgg ctgcaggaca aacactccaa
     2521 cacattatta cattaccgtt taaagattta tttgtattta ttggtggcgg tggagcgact
     2581 attggtcttg cgatttgtct cttcctattt agtaagagtc gtgcgaataa aacattaggt
     2641 aagctagcta ttataccgtc tatttttaat atcaatacag ctattctatt tacgtttcca
     2701 acagttttaa atccgattat gctgattccg tttattgcta ctcctacaat caatgccttg
     2761 attacctatg tatcaatggc tgtaggatta gtaccctata caacaggtgt aatccttccg
     2821 tggacaatgc caccgattat aggaggcttc cttgcaacag gggctagttg gcgaggagct
     2881 ctattacaag ttgttttgat tttggtttct gtagcaattt attatccatt cttcaaaatt
     2941 gcagataaac gcaatcttga aaaagaaaaa gctactgttg gagggaaata agatggttat
     3001 cagagtattt gatcaacaga aaaatactta ttctagcttt gccttagagg aattaagtta
     3061 ctatatgaat cgggtcttta agactaacat agagcttgtc gaggagaagg aagcggatat
     3121 ttttgtagga ttagtcaata aagaggacag aaaagaccat gttcttatct cattagacaa
     3181 gggtaaggga agaattgagt ctaatacaat tgtaggttta cttattggaa tttaccgaat
     3241 gtttcatgaa tttggggttg tgtatactag accagggcgc agacatgact ttgttccaga
     3301 gttacgattt gaagattttt tagataaaca gctatctata gatgaaacag ccagttacta
     3361 tcatagggga gtatgtatag agggagcgga ttcatttgaa aatatactag atttcattga
     3421 ttggctacct aagattggga tgaacagttt tttcatccag tttgaaaatc cttactcttt
     3481 tttgaaacgt tggtatgaac atgaatttaa tccatatcta aataaagaac aattttcaaa
     3541 tgaattagta caagaattga gtgataggtt ggataaagaa ttgcaaaaaa gaggtcttat
     3601 tcatcatcgt gttggtcatg gatggacagg tgaagtttta ggttactctt caaaatttgg
     3661 ctgggaatca ggtcttagta tttcagagga gaagaaaccc tatgtcgctg aaataaacgg
     3721 gaaacgagaa ttgtttaata cggctccgat tttaaccagc ctggattttt caaatccaga
     3781 tgtagctgat aagatggtag aaattatcaa ggattatgcc aagaaaagac ctgatgttaa
     3841 ctacttacat gtatggttgt cggatgctcg taataatatt tgtgaatgcg aaaactgtag
     3901 acaagaattg gtttcggatc agtatattcg tattctcaat caattggata gggctttaac
     3961 gagtgaggga ttagatacaa agatttgttt tctgctttac catgagttgc tatgggcgcc
     4021 tcagaaagaa aaattagata atcctgaacg ctttaccatg atgtttgcac cgattacaag
     4081 aacatttgaa atgagttatg cagatgtaga ttttgacaat tccataccta cgcctaaacc
     4141 ttatctgcgt aataaaatta tacttccgaa ttctcttgag gaaaatttat cttatctttt
     4201 tgagtggcaa aaaacattta aaggagatag tttcgtatat gactatcctt tagggcgtgc
     4261 tcattatggc gatttaggct atatgaaaat tagtcaaacc atttacagag atgtatctta
     4321 tctttctaac ctacatttga acggttacat ttcgtgtcaa gaattacgtg ccggattccc
     4381 tcataatttt cctaattatg ttatggggga aatgctctgg aagaagacaa gaagttatga
     4441 agaattgatt gaagaatact tttctgcttt gtatgggtca aattggcagt ctgttgttga
     4501 atatttagaa aaattatcca gttattcctc atgtgattat tttaatgcaa ttggcagtcg
     4561 tcaaaatgat gttttagcga atcattatta tatagcttac aatctagctg ataatttttt
     4621 gccaattatt gaggaaaata tttctaagtt attaaatagt caaaaggatg aatggaaaca
     4681 gctcagttat catcgtgaat atgttgttaa gatggcgaag gctttatatc ttcaagcaac
     4741 cggaaaaaca aggcaagctc aagatgaatg gagaaatgtg ttgaattata tccgtgggca
     4801 cgaactgcta ttccaatcta atttggatgt ttatcgtgta attgaagtag caaaaaatta
     4861 cgctggtttc cacttataaa tcataagtat agaaaatgaa ccaaggtatt cagagaagat
     4921 tgatcctaaa tattatgaaa tttaaggatt tttaagatat ttagggtcga ctttctattt
     4981 atatcgtagc gaagtcattt taataatgat gtgtaaaaga tggatcaaga ttgaggagga
     5041 agaaagatga aatcaaaaga agaaataaat atgcttggtt ttacaattgt cgcttacgca
     5101 ggagatgcaa ggtcagattt gatggatgct ttggcgtttg cgagagatgg atattttgaa
     5161 caggcaagag aattggttga gtctgcaaac gactcaatag tgtctgccca tcgagaacag
     5221 actaatttat tagcggagga ggcatctgga gataattttg aagtgagttt tatcatgatt
     5281 catggtcaag ataccttgat gacaacgatg ctattgtatg atcaggtcaa gttttttatt
     5341 gatgaatatg aacgaattcg aaagattgaa gaacatattg gtttgcaatg aggattagtc
     5401 atggaaaatt tacaggttaa agccttaccg aaggagtttt tattaggagc tgctaccgct
     5461 gcttatcaag tagagggtgc aactagggta gatggcaaag gaacaaatat gtgggatgtt
     5521 tatttgcaag aaaacagtcc gtttttacca gatccggcta gtgattttta ttatcgttac
     5581 gaagaggata tagctttggc ggcagaacat ggtttgcagg ctttgcgttt atctatttct
     5641 tgggttcgta tatttcctga tatagatggg gagcctaata tattagctgt tcgttattac
     5701 catagagtct ttcagtcttg cttaaaacat aatgtgattc cgtttgtttc tttacatcat
     5761 tttgattcgc ctcagaaaat gttagaaaca ggggattggt tgaatagaga gaatattgat
     5821 cgtttcatac gatatgctcg cttttgtttc caagaattta cagaagtcaa gcattggttt
     5881 acaatcaatg aactgatgtc tcttgctgca ggtcaatata taggaggtca gtttcctcca
     5941 aatcatcatt ttcaattatc tgaagcaatt caagcgaatc ataatatgtt gttggcgcat
     6001 gctcttgcag tccgcgaatt tcatcaatta gggattgagg gaaagatagg ttgtattcat
     6061 gctttaaagc caggctatcc tattgatggg caaaaagaaa atattttggc agctaaacgg
     6121 tatgatgttt ataataataa atttctatta gatggaactt ttttgggcta ctacagtgag
     6181 gacacgcttt ttcacttgaa tcaaatattg gaagctaata attctagctt tattattgaa
     6241 gatggtgatt tagaaattat gaagagagct gcagctctta atacgatgtt tgggatgaat
     6301 tattatcgtt cagaatttat tcgtgaatac aaaggtgaaa atagacaaga atttaattca
     6361 acaggaataa aaggacagtc ttcttttaaa ttaaatgctc taggtgaatt tgtaaaaaaa
     6421 cctggtattc cgacaacaga ttgggattgg aatatttatc ctcaagggtt atttgatatg
     6481 ttgcttcgta tcaaagaaga atatcctcaa catccggtca tttatttaac tgaaaatggt
     6541 acagccctta aagaagttaa gccagagggc gagaatgata ttattgatga cagtaagaga
     6601 atccgttata ttgagcaaca tttacacaaa gttttagagg ctcgagatag aggagtcaat
     6661 attcaaggct attttatatg gtctttgcaa gatcaatttt cttgggcgaa tggctacaat
     6721 aagcgatatg gtcttttctt tgttgattat gaaacacaga agagatatat taagaaaagt
     6781 gctctttggg taaaagggct aaaacggaat taaggttagc gatttgactg atgtttaata
     6841 tattttaact atgagcttaa attttttaca ggaggagttt ttatggataa gttagtcgct
     6901 gccattgaaa agcaacaagg gaaatttgaa aaaatttcta ctaataatta tatgatggct
     6961 attaaagatg gatttattgc tactatgcct ttaattatgt tttcaagctt tttgatgatt
     7021 attattatga ttcctaaaaa tttcggagta gagttaccga gtccagctat tgcctggatg
     7081 aggaaagtgt atatgctaac catgggagtt ttgggtatta ttgtttcagg gacagttgca
     7141 aagtcattgg ctggaaatgt taatagaaaa atgcctcctg gaaaggtaat aaatgatact
     7201 tctgcaatgt tggcggccat atgtggctat cttgtattaa ctgtaacgct tgtagttgat
     7261 gagaaaacgg gatctacaag tttgtcgaca aactatttag gatctcaagg attgataact
     7321 tcgtttgtca gtgcctttat tactgtaaat gtttaccgat tctgtattaa gcgagacatt
     7381 actattcatt tacctaagga agttcctggg gctatatcac aagcttttag agatattttt
     7441 cctttttctt ttgttttact tattagtggt ttgttagata ttgtatctcg ttttagttta
     7501 gatgttcctt ttgcccaagt atttcaacaa ctattgactc ctatttttaa gggggcagaa
     7561 tcatatcctg ctatgatgtt gatttggttt atgtgtgctt tgctttggtt tgttggaatt
     7621 catggaccat ctattgtctt acctgctgtt acagctttac aactgagcaa tatggaagag
     7681 aatgctcaac ttcttgcaaa tgggcagttc ccttatcatt ctttaacacc taatttcggg
     7741 aattatatcg ctgctattgg aggaacgggg gctacctttg ttgtaccatt tattttgatt
     7801 ttctttatgc ggtctaaaca attaaaatcg gtaggtaaag ctacaattac tcctgtttta
     7861 tttgcggtaa atgaacctct tctatttggt atgcctgtta ttttgaatcc ctatcttttt
     7921 gtaccttttt tgatgactcc accagtgaat gtatttctag gaaaggtatt tattgatttc
     7981 tttggaatga atggatttta tatccagtta ccttgggcct ttcctggtcc cttgggattg
     8041 ttaattggaa cgaattttca acttatctcc tttgtatttt tatctttgat gttagttgtc
     8101 gacatattga tttatttgcc attctgtaga gcgtatgata gacagttact ggtgaaagaa
     8161 gatattgcaa gctcaaatga tattatttta gaggaggata caagtgaaat aatgccttgt
     8221 gagatagatg taataaaaag taaggagttg aaagtactgg ttctttgtgc agggtctgga
     8281 acaagtgcgc aattagccaa tgcaattaac gagggcgctc aattagcaga agttagagtg
     8341 attgcgaatt caggagcgta cggagctcat tatgatatta tgggtgttta tgatttaatt
     8401 attctggccc cacaagttcg gagttattat agagagatga aggtggatgc agaaagatta
     8461 ggtattcaga tagttgctac cagaggaatg gaatatattc atttaacaaa gagtccaagt
     8521 aaagccttac aatttgtatt ggagcattac caagctgtgt agtaagtttt tccatctttt
     8581 atttgagtaa agattttgct tacagatagg cttggattta aaaacgttcc ccctttttta
     8641 atataagaat ccctctttca caattgtaaa aagagggatt ttgtatttta tctcttagac
     8701 caagttctct tcataaagag aaggaggatt gggtaaatct ccaagcgccc tgcaatcatt
     8761 gcaaaggata ggagaatttt tgagatggga ctaaagattg agaaactaga agtggttcct
     8821 agaataggcc cgatattatt gaaacagcta aagacagcgc tggtcacgac cagaaaatca
     8881 ttgctatcta ggctgacaat aaagataagc gctagcaaaa tcatagcata gatgacaaag
     8941 tacttgagaa tcttatgctg ggtatctttg tcaatcaccg ttttattaac atggagggtc
     9001 aaaacacggt ggggcgatag gattgacaaa atttggtttt tggcaatttt tgaaaggatg
     9061 aggcctcgaa taatcttgag tccacctgca gttgatccag cagagccacc gattgccatg
     9121 aggaaaagga ggataaactg ggagaagagg ggccagttgg taatatctcc atatccaaaa
     9181 ccagttgttg taatgatgtt ggaaacctgg aagaaggtca tttcaaagct ctttgaaaac
     9241 cctgggtaga ggtagagggt gttgaggcta atcaagcctg tagaaaccag tacaatgacc
     9301 aagtaagccc gaagttcttc gtcaccaaag aaggccttga tgcgacggag catgaggtag
     9361 tagtagaggt tgaaatttac cccaaaaacc agaactccga tactgaccag ataggtaatc
     9421 agtgagctgc catagtgggc aattccgtcg ttatagacgg taaagcctcc agttcccgct
     9481 gtccccatag caatgacaaa actatcgtag agaggcatac cagctagata atagatgatg
     9541 acaaagaggg agaagagagc tagataaagg agatagagaa tctgggcagt gttttttagt
     9601 ttggatacaa ccttgccaaa aacaggacct ggaacctcag ccttcatcac ctctaggtgg
     9661 ctatttttgg cattgtccat aatagcaagt gcaaaaacaa gcactcccat ccctccaatc
     9721 aagtgggtaa aacttcgcca gaagaggagg gaacggctga gaaccgaaat gtcgttcaaa
     9781 atacttgctc cagtagttgt aaacccagaa ctaatttcaa aaaaggcatc aataacgcta
     9841 gggatttgcc cagaaaagac aaaggggaga ccaccaaaga aagaccaaag gatccaacag
     9901 agggcaacga tcaagactcc ctccttggca taaatccgtt gattttttgg cttctgtaaa
     9961 ctccctgaac cgcctaacaa tacgagaatc cctatggtcg aaaagagggc tgtaaagact
    10021 tggctcgatt cacggtaata gacagcgata gccacaggaa ccaagaggag aacagcttca
    10081 atcaaaagta actttgaaag gaggtaacga atcatacttt tattcatttc ttacctcgca
    10141 atcaagtcat aaatcttggt gatgtttggc aacaaggttg ttactaggag cttgtctcca
    10201 acttccaaca tatcctcccc agttgggaaa atagtcttgc cctttcgaat aatggctgca
    10261 ataagaaccc cttttttcaa tttcagttga gaaagaggtt tggcagtcat tttattggct
    10321 tccttgatat ggaattgcag ggtttcaatt tggccattgg ctagatggtg catggcttga
    10381 aggtctgaat actgggcatt aactcgacca cgaataaagt gcataatcgt atctacagcg
    10441 atgcttttag gtgtgatgat acttgaaaaa tcaggcgcat tgataatctc gaggagactg
    10501 gtacgattga ccttagtaat atttttctgt acacctaccc tgtcaaggaa catagatgta
    10561 atcagatttt cctcatcgac acctgttaga gtcgcaacgg catcatagtg ttgagcactt
    10621 tcttccagca ggatatcttt tgcggttcca tctccttgaa cgatgtagag atttgggaat
    10681 ttctcgctaa agaagctggc gatttcagga ttgatttcaa tgacttttgt atcgatacga
    10741 ctatctttga gaataccaag tagataatag gcaattctac ctgccccaac gatgagaagg
    10801 ctcttcacgg cgcgtgattt aaaataatta tggaagagta tcatatcgac acggttacca
    10861 gtgacaaaga ttctatcttt atcctgtaca gtcatgtcac cgcttggaat gataatttga
    10921 tgatccctct ctatcgcaca gacaatgaca ttaccaaatt ttttacgaaa atcagaaatg
    10981 ggcatttggc aaagaccgct ggtggacttg acgacaaatt ccatgaggct aacgcgtcca
    11041 ccagcaaagc gttcgacaga cagggcgttg gggaagtcaa tgatattcgc gatagcgcgg
    11101 gcagccaaga gctcaggatt aacgataaga gaaaaaccga gaatattctt ttccttgaaa
    11161 taagagttag aatattcagg gttccgcacc cgaacgatag tttctttagc tcccattttc
    11221 ttggctagaa ctgctgcaat catgttgact tcatcgtgct cagtcagggc gataaagata
    11281 tcacaatctt ggacgctggc ttgctcaaga atggcaaaat cggccccgtt accaaggata
    11341 ccaatgatat caaagcgatt gacaatatga ttgagaacag cttcgtcttg ctcaatcagc
    11401 aaaacatcat gcttttctgc aaccaaggag cgacagaggg caaaaccaac ttttccccct
    11461 ccgacaagga taattttcat aataaaacct actttttcat gatgtaacta tcataccctt
    11521 tttcaagaaa aaatgcacct actagctaat aacaagagct tttagtgaaa attcgctata
    11581 aggtaaaact ataccctaac caattgaaat agctattagc gactttctct gaaatatggt
    11641 atgataaagg atatacaagg agataaaatg aataataatt tactggtatt acaatcagac
    11701 tttggtctgg ttgatggtgc ggtatcggct atgattggag tggctttaga agagtctcca
    11761 accttaaaaa tccatcactt gacgcacgat atcacgcctt ataatatttt tgaggggagc
    11821 tatcgtctct ttcagacggt ggattactgg cctgagggaa cgacgtttgt atcggttgtc
    11881 gatccaggtg tcggttcgaa acgtaagagt gtagttgcca agactgcaaa aaatcaatac
    11941 attgtcacgc cagataatgg gacgctttcc tttatcaaga aacacgttgg cattgtagcc
    12001 attcgtgaga tttctgaggt ggccaatagg cgtcaaaaca cagagcattc ttataccttc
    12061 cacggtcgtg atgtctatgc ctatactggt gctaaactgg ccagtggtca cattactttt
    12121 gaggaagtag ggccagagct cagtgtggaa cagattgtag agcttccagt cgtagcgacc
    12181 atcatagaag atcatctggt gaagggagcc attgatattc tggatgtgcg tttcggttcg
    12241 ctttggacct ctatcacacg ggaagaattt tacaagctgg aaccagaatt tggtgatcgt
    12301 tttgaagtga ccatctatca tgctgatatg ctggtctatc aaaatcaggt tgtctatggc
    12361 aaatcatttg cagatgtgag aattgggcaa cccatccttt acatcaactc tctctatcgt
    12421 ttaggtttgg ctatcaacca aggttccttt gccaaggcct ataatgtagg tgtcggttca
    12481 tcttggacca ttgaaataaa gaaaatagaa ggataaaata ggagaatagt atggaaatca
    12541 aatttacaat taaacaagtt gttgctgtcg gaattggcgc tgccctcttt gtcgtcatcg
    12601 ggatgatcaa cattccaacc cctgttccaa atacaagcat ccagcttcag tatgcggtac
    12661 aagcgctact ttctattatt tttggaccga ttatcggttt gcttgtcggg ttgattggtc
    12721 atgcaatcaa ggactctctt gctggttatg gtctatggtg gacttggatt atcgctagcg
    12781 gactttttgg tctagttgtg ggacttttta gaaagtacgt tcgagtgatc aatggtgttt
    12841 ttgactggaa agatattctt atttttaacc tcattcaact acttgcaaat gcccttgttt
    12901 ggggtgtctt ggcaccactt ggagatgttg tgatttatca agaagcggca gaaaaagtat
    12961 ttgcacaagg gattgttgcg ggaattgcca atggtgtatc tgtagctatt gcaggaactc
    13021 ttctcttact tgcctatgca ggaacccaaa ctcgtgcagg aagtttgaaa aaggactaat
    13081 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacagtgtt
    13141 ttgagattgt
//
LOCUS       DAVBOU010000056        12973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBOU010000056 DAVBOU010000000
VERSION     DAVBOU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.056"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ879_001822"
     CDS             87..3437
                     /locus_tag="VQ879_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3143932.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTDTPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ879_001823"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ879_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ879_001824"
     CDS             complement(4023..4493)
                     /locus_tag="VQ879_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3143933.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ879_001825"
     CDS             complement(4510..6783)
                     /locus_tag="VQ879_001825"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3143934.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7129..10230
                     /locus_tag="VQ879_001826"
     CDS             7129..10230
                     /locus_tag="VQ879_001826"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3143935.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YKLSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ879_001827"
     CDS             10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ879_001827"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3143936.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11379..12884
                     /gene="pyk"
                     /locus_tag="VQ879_001828"
     CDS             11379..12884
                     /gene="pyk"
                     /locus_tag="VQ879_001828"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3143937.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4023 a         2203 c         2850 g         3897 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gatactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     7081 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     7141 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     7201 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     7261 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     7321 gaaatgacag tgtttgtaga tgaacaggaa gtgaatttgc gctttttatc tctatctagt
     7381 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     7441 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     7501 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     7561 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     7621 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     7681 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
     7741 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     7801 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     7861 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     7921 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     7981 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     8041 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     8101 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     8161 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     8221 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     8281 ttgaaacgct ttggtgtgcc agagtataaa ttatctgcaa ttactaagaa aatcagtttt
     8341 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     8401 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     8461 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     8521 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     8581 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     8641 gagttgcttg ctgaaacaga aggtattcac cttaaaattg aagaaataga tttggaagac
     8701 aaagaaacgt tagatttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
     8761 cctggtgcca ttcgcttgct caaacgtgtt caaccagtct gttttgaaga tgtcgtagca
     8821 actacttctc taaatcgacc aggtgcaagt gactacatca ataattttgt ggcaaggaag
     8881 catgggcagg aagaagtgac tgttctagat tcagctctgg aggatatttt ggctccaact
     8941 tatggcatta tgctctatca ggagcaggtt atgcaggttg ctcagcgatt tgctggattt
     9001 agtcttggga aggccgatat tttgcgtcga gctatgggta aaaaggatgc ctctgctatg
     9061 catgagatga gggcttcctt tattcaaggc tccatagaag caggccatac tgcggaaaaa
     9121 gcagagcagg tttttgatgt tatggagaag tttgcaggtt atggatttaa tagatctcat
     9181 gcctacgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     9241 attttttatc aggtcatgtt aaattattcc aacagtgatt acttaataga tgcacttgaa
     9301 gcaggttttg aagtagcctc tctatccatc aatactattc cctatcacga taaaattgcc
     9361 aacaagtcta tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt
     9421 tggattattg aacatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     9481 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     9541 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     9601 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     9661 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     9721 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     9781 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     9841 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt
     9901 tcagacttat atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa
     9961 ggaaaaatac aatcacgtga tggccgtttg caaatgattg cacaagaaat aagagaagca
    10021 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
    10081 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
    10141 accatcgttt ctccccatca ttttgtagct aaatccaatg aattagagga gaaattgaat
    10201 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
    10261 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaacca atatgaaacg
    10321 tattgctgtt ttgactagtg gcggagacgc acctggtatg aacgctgcta tccgtgcagt
    10381 tgttcgtcaa gcaatttcag aaggaatgga agtgtttggt atctatgacg gatatgctgg
    10441 tatggttgcc ggtgaaattc atcccctaga tgcagcttca gtaggagaca tcatttctcg
    10501 tggtggtact tttcttcact cagctcgtta cccagagttc gctcaacttg aagggcaact
    10561 taaagggatt gagcaattga aaaaacacgg aattgaaggt gtagttgtta tcggtggtga
    10621 cggatcttac cacggcgcta tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc
    10681 aggtacaatc gataacgata tcgttggtac tgactttaca atcggttttg acacagcggt
    10741 tactactgcc atggacgcta tcgataagat tcgtgataca tcatcaagtc accgtcgtac
    10801 ttttgtaatc gaagttatgg gacgtaacgc tggtgatatc gctctttggg ctggtattgc
    10861 aactggtgct gatgaaatca tcatccctga agcaggcttc aagatggaag atatcgtagc
    10921 aagcatcaaa gctggttatg aatgtggtaa aaaacacaat atcatcgtct tagctgaagg
    10981 tgtgatgtca gcggctgaat ttggtcaaaa acttaaagaa gctggagata caagcgacct
    11041 tcgtgtaaca gaacttggac atattcaacg tggtggttct ccaactgcgc gtgaccgtgt
    11101 tttagcgtca cgtatgggtg cacatgctgt taaacttctt aaagaaggta tcggtggtgt
    11161 tgcggttggt attcgtaacg aaaaaatggt tgaaaatcca attcttggta ctgcagaaga
    11221 aggggcattg tttagcctta ctgcagaagg taagattgtg gttaacaacc cgcacaaagc
    11281 cgatattgag ctatctagct tgaataagag cttgtcataa tttacaattt agttaataag
    11341 accaaaaagg tcatatatat aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg
    11401 ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat
    11461 actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag
    11521 ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc
    11581 gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg
    11641 atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat
    11701 acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag
    11761 tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc
    11821 aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc
    11881 gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca
    11941 tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt
    12001 tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg
    12061 tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta
    12121 aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta
    12181 ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc
    12241 aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca
    12301 tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca
    12361 acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat
    12421 acccactcga gtcagtaact acaatggcta caatcgacaa gaacgctcaa gctcttctta
    12481 atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg
    12541 cttctgctgt taaagatgct actaactcaa tggatatcaa attggttgta actcttacta
    12601 agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat
    12661 tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt
    12721 tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag
    12781 aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag
    12841 aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc
    12901 tatcatatcc agctttctag cctgtatgat gggctctttt tttgtccagg gggcaaaact
    12961 ttcataatgg att
//
LOCUS       DAVBOU010000057        12134 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBOU010000057 DAVBOU010000000
VERSION     DAVBOU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12134
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.057"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            462..689
                     /locus_tag="VQ879_001829"
     CDS             462..689
                     /locus_tag="VQ879_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143938.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            977..4114
                     /gene="nanA"
                     /locus_tag="VQ879_001830"
     CDS             977..4114
                     /gene="nanA"
                     /locus_tag="VQ879_001830"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3143939.1"
                     /translation="MNRSIQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAE
                     LPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKTVWGSNLQVRNLTV
                     YDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEG
                     AIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPL
                     GTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEFTG
                     GVNGTEPAVHEIAEYKGSDSLVTLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLT
                     AFFLGLFTLGKKREQ"
     gene            5129..5581
                     /locus_tag="VQ879_001831"
     CDS             5129..5581
                     /locus_tag="VQ879_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3143940.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5600..6937
                     /locus_tag="VQ879_001832"
     CDS             5600..6937
                     /locus_tag="VQ879_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3143941.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            7016..7900
                     /locus_tag="VQ879_001833"
     CDS             7016..7900
                     /locus_tag="VQ879_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3143942.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7900..8733
                     /locus_tag="VQ879_001834"
     CDS             7900..8733
                     /locus_tag="VQ879_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3143943.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8751..10844
                     /gene="nanB"
                     /locus_tag="VQ879_001835"
     CDS             8751..10844
                     /gene="nanB"
                     /locus_tag="VQ879_001835"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3143944.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10856..11959
                     /locus_tag="VQ879_001836"
     CDS             10856..11959
                     /locus_tag="VQ879_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3143945.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         4073 a         1941 c         2542 g         3578 t
ORIGIN      
        1 cgtcagttct atctgccacc tcaaaacggt gttttgagct gacttcgtca gttctatctg
       61 ccacctcaaa acggtgtttt gagctgactt tgtcagtctt atctacaacc tcaaaacagt
      121 gttttgagca tcatgcggct agcttcttag tttgctcttt gattttcatt gagtataaaa
      181 acagatgagt ttctgttttc tttttatgga ctataaatgt tcagctgaaa ctactttcaa
      241 ggacattatt atataaaaga attttttgaa actaaaatct actatattac actatattga
      301 aagcgtttta aaaatgaggt ataataaatt tactaacgct tataaaaagt gatagaatct
      361 atctttatgt atatttaaag atagattgct gtaaaaatag tagtagctat gcgaaataac
      421 agatagagag aagggattga agcttagaaa aggggaataa tatgatattt aaggcattca
      481 agacaaaaaa gcagagaaaa agacaagttg aactactttt gacagttttt ttcgacagtt
      541 ttctgattga tttatttctt cacttatttg ggattgtccc ctttaagctg gataagattc
      601 tgattgtgag cttgattata tttcccatta tttctacaag tatttatgct tatgaaaagc
      661 tatttgaaaa agtgttcgat aaggattgag caggaagtat ggtataaata gcataagctg
      721 atgtccatca tttgcttata aagagatatt ttagtttaat tgcagcggtg ccctggtaga
      781 taaactagat tggcaggagt ctgattggag aaaggagagg ggaaaattgg caccaatttg
      841 agatagtttg tttagttcat ttttgtcatt taaatgaact gtagtaaaag aaagttaata
      901 aaagacaaac taagtgcatt ttctggagta aatgtcttat ttcagaaatc gggatataga
      961 tatagagagg atcagtatga atcggagtat tcaagaacgt aagtgtcgtt atagcattag
     1021 gaaactatcg gtaggagcgg tttctatgat tgtaggagca gtggtatttg gaacgtctcc
     1081 tgttttagct caagaagggg caagtgagca acctctggca aatgaaactc aactttcggg
     1141 ggggagctca accctaactg atacagaaaa gagccagcct tcttcagaga ctgaactttc
     1201 tggcaataag caagaacaag aaaggaaaga taagcaagaa gaaaaaattc caagagatta
     1261 ctatgcacga gatttggaaa atgtcgaaac agtgatagaa aaagaagatg ttgaaaccaa
     1321 tgcttcaaat ggtcagagag ttgatttatc aagtgaacta gataaactaa agaaacttga
     1381 aaacgcaaca gttcacatgg agtttaagcc agatgcatca gctccacgct tttacaatct
     1441 cttctctgta tccagtgaca ccaaggaaaa tgagtacttt actatgtcgg tccttgataa
     1501 tacagctctt attgaagggc gtggcgctaa cggagagcag ttctatgata agtatacaga
     1561 tgctcctttg aaagttcgcc caggacaatg gaattccgtg acctttactg tcgaacaacc
     1621 gacagcggag ttacctcatg gacgagttcg tctctatgtg aacggtgtct tatctcgaac
     1681 aagtctcaaa tctggtaact ttatcaaaga tatgccagat gttaatcaag ctcaacttgg
     1741 agcaaccaaa cggggcaata agacagtttg gggaagcaat ctacaagttc gaaacctaac
     1801 cgtctatgat cgtgccttaa gcccagaaga agttcagacg agaagccaac tatttgaaag
     1861 aggtgatttg gagaagaaac ttccagaagg tgcgaaaatc tcagagaaag aagacgtctt
     1921 tgaaggggga atgaacaaca aaccaaataa agatggaatt aagagttatc gtattccagc
     1981 tcttctcaag acagataaag gaactttgat cgcaggtgca gatgaacgcc gtctccattc
     2041 gagtgactgg ggtgatatcg gtatggtcat cagacgtagt gaagataatg gtaaaacttg
     2101 gggtgaccga gtaaccatta ccaacttacg tgacaatcca aaagcttctg acccatcgat
     2161 cggttcacca gtgaatatcg atatggtgtt ggttcaagat cctgaaacca aacgaatctt
     2221 ttctatctat gacatgttcc cagaagggaa gggaatcttt ggaatgtctt cacaaaaaga
     2281 agaagcctac aaaaaaatcg atggaaaaac ctatcaaatc ctctaccgtg aaggagaaaa
     2341 gggagcttat accattcgag aaaatggtac tgtctataca ccagatggta aggcgacaga
     2401 ctatcgcgtt gttgtagatc ctgttaaacc agcctatagc gacaagggtg atctatacaa
     2461 gggtgaccaa ttactaggaa atatctactt cacaacaaac aaaacttctc catttagaat
     2521 tgccaaggat agctatctat ggatgtccta cagtgatgac gacgggaaga catggtcagc
     2581 tcctcaagat attactccga tggtcaaagc cgattggatg aaattcttgg gtgtaggtcc
     2641 tggaacagga attgtacttc ggaatgggcc tcacaaggga cggattttga taccggttta
     2701 tacgactaat aatgtatctc acttagatgg ctcgcaatct tctcgtgtca tctattcaga
     2761 tgatcatgga aaaacttggc atgctggaga agcggtcaac gataaccgtc aggtagacgg
     2821 tcaaaagatc cactcttcta cgatgaacaa tagacgtgcg caaaatacag aatcaacggt
     2881 ggtacaacta aacaatggag atgttaaact ctttatgcgt ggtttgactg gagatcttca
     2941 ggttgctaca agtaaagacg gaggagtgac ttgggagaag gatatcaaac gttatccaca
     3001 ggttaaagat gtctatgttc aaatgtctgc tatccatacg atgcacgaag gaaaagaata
     3061 catcatcctc agtaatgcag gtggaccgaa acgtgaaaat gggatggtcc acttggcacg
     3121 tgtcgaagaa aatggtgagt tgacttggct caaacacaat ccaattcaaa aaggagagtt
     3181 tgcctataat tcgctccaag aattaggaaa tggggagtat ggcatcttgt atgaacatac
     3241 tgaaaaagga caaaatgcct ataccctatc atttagaaaa tttaattggg aatttttgag
     3301 caaaaatctg atttctccta ccgaagcgaa agtgaagcga actagagaga tgggcaaagg
     3361 agagatgggc aaaggagtta ttggcttgga gttcgactca gaagtattgg tcaacaaggc
     3421 tccaaccctt caattggcaa atggtaaaac agcacgcttc atgacccagt atgatacaaa
     3481 aaccctccta tttacagtgg attcagagga tatgggtcaa aaagttacag gtttggcaga
     3541 aggtgcaatt gaaagtatgc ataatttacc agtctctgtg gcgggcacta agctttcgaa
     3601 tggaatgaac ggaagtgaag ctgctgttca tgaagtgcca gaatacacag gcccattagg
     3661 gacatccggc gaagagccag ccccgacagt cgagaagcca gaatatacag gtccattagg
     3721 gacatccggt gaagagccag ctccaacagt cgagaagcca gaatacacag gcccactagg
     3781 gacatccggc gaagagccag ccccgacagt cgagaagcca gaatacacag gcccactagg
     3841 gacagctggt gaagaagcag ctccaacagt cgagaagcca gaatttacag ggggagttaa
     3901 tggtacagag ccagctgttc atgaaatcgc agagtataag ggatctgatt cgcttgtaac
     3961 tcttactaca aaaaaagatt atacttacaa agctcctctt gctcagcagg cacttcctga
     4021 aacaggaaac aaggagagtg acctcctagc ttcactagga ctaacagctt tcttccttgg
     4081 tctgtttacg ctagggaaaa agagagaaca ataagagaag aattctaaac atttgatttt
     4141 gtaaaaatag aaggagatag caggttttca agcctgctat ctttttttga tgacattcag
     4201 gctgatacga aatcataaga ggtctgaaac tactttcaga gtagtctgtt ctataaaata
     4261 tagtagattg aaataagatg tgaacaactc tatcaggaaa gtcaaattaa tttatagaaa
     4321 aattttagca gtcaaggtgt actgttatag attcaatata ttatgcgact attaaccttg
     4381 tcttctccta aaattgactt tcttgttttc ttatcttgtc cactcgaaac aagtattgta
     4441 agaatttgat tatttttgaa agtactttta atatacttga tatagttaaa aaagatttga
     4501 aactaaattc caaattagaa aaagacttga aatactaaaa aaaaaaagta tactctaatt
     4561 gaaaacggta acaaaactaa tttagagaat gaaatataga gtatttctct cttaaaagtt
     4621 tttggtgaaa cgagatgtag aaaggagatt tagccaaaga gtctattagt gctagaataa
     4681 tagattagaa ttattttaga aaaacgaagt gagcagctta taaattcaag tccccaaata
     4741 gattcatact agtatctttt gcaaaaaata aagggcgact tccttcatga atatcaattt
     4801 catctataag gaaggtagct aattgaacta acttatttat tctgtttgtc gctagaaaaa
     4861 tcagacctcc ttgtgaagat tgaggagata ctgaatgaaa atcaaagaag aaactagcaa
     4921 gctagtagca gattgcccaa aacaccgctt tgaggttgta gataagactg acgtatataa
     4981 tccaaggtga agcgactgtg gtttgaagag attttcaaag agtataggct agagagtagt
     5041 gtttttatgt ccttctagta gaaaatgcta gacagaagaa tggggaactt ggataggaaa
     5101 aatagattga gaaaggaggt tagaagagat gattattaca aaaattagcc gtttaggaac
     5161 ttatgtggga gtcaatccac attttgcaac attaatagat tttctagaaa aaacaggact
     5221 agaaaattta acagaaggtt cgattgctat cgatggtaat cgattgtttg ggaattgctt
     5281 tatttatcta gcagatggtc aagcaggggc tttctttgaa acacaccaaa aatatttgga
     5341 tattcattta gttttggaaa acgaagaagc catggctgtt acatcgccgg aaaatgtaag
     5401 cgttacccaa gaatatgatg aagagaaaga tattgaatta tacacaggga aagtggaaca
     5461 gttggttcat ttgagagctg gtgaatgcct catcactttt ccagaagatt tacatcaacc
     5521 caaggttcgt ataaatgatg aacctgtgaa aaaagttgtc tttaaagttg cgatttctta
     5581 atgtagaaag agaagaacga tgaaaaaaat gagaaagttt ttatgtctag ctggaattgc
     5641 gctagcggct gttgccttgg tagcttgttc aggaaaaaaa gaagctacaa ctagtactga
     5701 accaccaaca gaattatctg gtgagattac aatgtggcac tcctttactc aaggaccccg
     5761 tttagaaagt attcaaaaat cagcagatgc tttcatgcaa aagcatccaa aaacgaaaat
     5821 caagattgaa acattttctt ggaatgactt ctatactaaa tggactacag gtttagcaaa
     5881 tggaaatgtg ccagatatca gtacagctct tcctaaccaa gtaatggaaa tggtcaactc
     5941 agatgctttg gttccgctaa atgattctat caagcgtatt ggacaagata aatttaacga
     6001 aactgcctta aatgaagcaa aaatcggaga tgattactac tctgttcctc tttattcaca
     6061 tgcacaagtc atgtgggtta gaacagattt gttaaaagaa cataatattg aggttcctaa
     6121 aacttgggat caactctatg aagcttctaa aaaattgaaa gaagctggag tttatggctt
     6181 gtctgttccg tttggaacaa atgacttaat ggcaacacgt ttcttgaact tctacgtacg
     6241 tagtggtgga ggaagcctct taacaaaaga tcttaaagca gacttgacaa gccaacttgc
     6301 tcaagatggt attaaatact gggttaaatt gtataaagaa atctcacctc aagattcttt
     6361 gaattttaat gtccttcaac aagctacctt gttctatcaa ggaaaaacag catttgactt
     6421 taactctggc ttccatatcg gaggaattaa tgccaacagt cctcaattga ttgattcgat
     6481 tgatgcttat cctattccaa aaatcaaaga gtctgataaa gaccaaggaa ttgaaacctc
     6541 aaacattcca atggttgttt ggaaaaattc aaaacatcca gaagttgcta aagcattctt
     6601 agaagcactt tataatgaag aagactacgt taaattcctt gattcaactc cagtaggtat
     6661 gttgccaact attaagggga ttagcgattc tgcagcctat aaagaaaatg aaactcgtaa
     6721 gaagtttaaa catgctgaag aagtaattac tgaagctgtt aaaaaaggta ctgctattgg
     6781 ttatgaaaat ggaccaagtg tacaagctgg tatgttgact aaccaacaca ttattgaaca
     6841 aatgttccaa gatatcatta caaatggaac agatcctatg aaagcagcaa aagaagcaga
     6901 aaaacaatta aacgatttat ttgaggctgt tcagtagatg taaaagacta gaaaataggt
     6961 gggctagtga tctgaaaagc tctagcccaa ttttgtaaaa gaagggagaa ggagaatggt
     7021 taaagaacgt aatttaactc gctggatatt tgttttgcca gctatgatta tcgtaggatt
     7081 actctttgtt tatccgtttt tctcgagtat tttttatagc tttaccaata agcatttgat
     7141 tatgcctaat tataaatttg ttggtttggc taactataaa gctgtgctat cagatcccaa
     7201 cttctttaat gcgttcttta attcaattaa gtggaccgtt ttctcattag ttggtcaagt
     7261 tttagtaggg tttgtgttgg ctttagctct tcacagagta cgccacttca agaaattata
     7321 taggacctta ttgattgttc cttgggcatt tcctaccatc gttattgcct tctcttggca
     7381 gtggattcta aacggggttt atggctactt acctaatcta atcgtaaaat taggtttaat
     7441 ggaacataca cctgcatttt tgacagatag tacatgggca ttcctatgtt tggtgtttat
     7501 caacatttgg tttggagcac caatgattat ggttaatgtg ctttcagctt tgcaaacagt
     7561 accagaagaa caatttgagg ctgctaagat agatggtgct tcaagttggc aggtgttcaa
     7621 gtttatcgtc tttccacata ttaaagtggt tgtaggactt ctagttgttt tgagaactgt
     7681 atggatcttt aataactttg acattatcta cctcattact ggtggtggac cagccaatgc
     7741 tacaacgacg cttccaattt ttgcttacaa cctgggttgg ggaactaaat tgttgggtcg
     7801 tgcttcagca gttacagtat tgctctttat cttcttggtg gcgatttgct ttatctactt
     7861 tgctatcatc agtaagtggg aaaaggaggg tagaaaataa tgaagaagaa atccagtatt
     7921 tatttagata ttctctcaca tgtactttta gttggtgcga ccatcgttgc agttttccca
     7981 ttggtatgga ttatcatatc ttctgtcaaa gggaaagggg aattaactca gtatccaaca
     8041 cgattttggc ctgaacagtt tacattagat tatttcactc atgttatcaa cgatttgcac
     8101 ttcattgata acattcgaaa cagtttaatc attgccttgg ctacaaccct cattgcgatt
     8161 attatttctg ctatggcagc ctatggtatt gttcgattct ttcctaaatt gggagcaatc
     8221 atgtcgagac tactcgtcat tacctatatt ttcccaccaa ttttgttagc aattccctat
     8281 tcaattgcca ttgctaaagt tgggttaaca aatagtttat ttggcttgat gatggtttat
     8341 ctatctttta gtgttccata tgcagtttgg ctcttagttg gatttttcca aacagttcca
     8401 attggaattg aagaagcggc tagaattgat ggtgcaaata aatttgttac gttttataaa
     8461 gttgtgctac cgattgtagc accaggtatt gtagcaacag ctatttatac atttatcaat
     8521 gcttggaatg aattcctgta tgccttgatt ttgattaaca atacaggaaa gatgacagta
     8581 gcagtagccc ttcgttcact taatggttca gaaatactag actggggaga tatgatggca
     8641 gcgtctgtta ttgtagttct tccatcaatt attttcttct ctatcatcca aaataagatt
     8701 gcaagtggat tatcagaagg atctgtgaag tagacgaaag aaggaaaaaa atgaataaaa
     8761 gaggtcttta ttcaaaacta ggaatttctg ttgtaggcat tagtctttta atgggagttc
     8821 ccactttgat tcatgcgaat gaattaaact atggtcaact gtccatatct cctatttttc
     8881 aaggaggttc atatcaactg aacaataaga gtatagatat cagctctttg ttattagata
     8941 aattgtctgg agagagtcag acagtagtaa tgaaatttaa agcagatgaa ccaaactctc
     9001 ttcaagcttt gtttggccta tctaatagta aagcagactt taaaaataat tacttttcaa
     9061 ttttcatgag agattctggt gagataggtg tagaaataag agacgcccaa aagggaataa
     9121 attatttatt ttccagacca gcttcattat ggggaaaaca taaaggacag gcagttgaaa
     9181 atacactagt atttgtatct gattctaaag ataaaacata cacaatgtat gttaatggaa
     9241 tagaagtgtt ctctgaaaca gttgatacat ttttgccaat ttcaaatata aatggtatag
     9301 ataaggcaac actaggagct gttaatcgtg aaggtaagga acattacctc gcaaaaggaa
     9361 gtattgatga aatcagtcta tttaacaaag caattagtga tcaggaagtt tcaactattc
     9421 ccttgtcaaa tccatttcag ttaattttcc aatcaggaga ttctactcaa gctaactatt
     9481 ttagaatacc gacactatat acattaagta gtggaagagt tctatcaagt attgatgcac
     9541 gttatggtgg gactcatgat tctaaaagta agattaatat tgccacttct tatagtgatg
     9601 ataatgggaa aacgtggagt gagccaattt ttgctatgaa gtttaatgac tatgaggagc
     9661 agttagttta ctggccacga gataataaat taaagaatag tcaaattagt ggaagtgctt
     9721 cattcataga ttcatccatt gttgaagata aaaaatctgg gaaaacgata ttactagctg
     9781 atgttatgcc tgcgggtatt ggaaataata atgcaaataa agccgactca ggttttaaag
     9841 aaataaatgg tcattattat ttaaaactaa agaagaatgg agataacgat ttccgttata
     9901 cagttagaga aaatggtgtc gtttataatg aaacaactaa taaacctaca aattatacta
     9961 taaatgataa gtatgaagtt ttggagggag gaaagtcttt aacagtcgaa caatattcgg
    10021 ttgattttga tagtggctct ttaagagaaa ggcataatgg aaaacaggtt cctatgaatg
    10081 ttttctacaa agattcgtta tttaaagtga ctcctactaa ttatatagca atgacaacta
    10141 gtcagaatag aggagagagt tgggaacaat ttaagttgtt gcctccgttc ttaggagaaa
    10201 aacataatgg aacttactta tgtcccggac aaggtttagc attaaaatca agtaacagat
    10261 tgatttttgc aacatatact agtggagaac taacctatct catttctgat gatagtggtc
    10321 aaacatggaa gaaatcctca gcttcaattc cgtttaaaaa tgcaacagca gaagcacaaa
    10381 tggttgaact gagagatggt gtgattagaa cattctttag aaccactaca ggtaagatag
    10441 cttatatgac tagtagagat tctggagaaa catggtcgaa agtttcgtat attgatggaa
    10501 tccaacaaac ttcatatggc acacaagtat ctgcaattaa atactctcaa ttaattgatg
    10561 gaaaagaagc agtcattttg agtacaccaa attctagaag tggccgtaag ggaggtcaat
    10621 tagttgtcgg tttagtcaat aaagaagatg atagtattga ttggaaatac cactatgata
    10681 ttgatttgcc ttcgtatggt tatgcctatt ctgcgattac agaattgcca aatcatcaca
    10741 taggtgtact gtttgaaaaa tatgattcgt ggtcgagaaa tgaattgcat ttaagcaatg
    10801 tagttcagta tatagatttg gaaattaatg atttaacaaa ataaaggaga aaaacatggt
    10861 taaatacggt gttgttggag cagggtattt tggagctgaa ttggctcgct acatgcaaaa
    10921 gaatgatgga gcagagatta ctcttctcta tgatccagat aatgcagagg cgattgcaga
    10981 agaattgggg gcaaaagtag caagttcctt agatgagttg gtttctagcg atgaagtaga
    11041 ttgtgttatc gtcgcaactc caaataatct tcataaggaa ccggttatta aggctgcaca
    11101 gcatggtaaa aatgttttct gtgaaaaacc aattgcgctt tcttatcaag attgtcgcga
    11161 gatggtagat gcgtgtaaag aaaacaatgt aacctttatg gcaggacata ttatgaattt
    11221 ctttaatggt gttcatcatg caaaagaact cattaatcaa ggagttatcg gagacgttct
    11281 atattgtcat acagctcgta atggttggga agaacaacaa ccgtcagtat catggaaaaa
    11341 aattcgtgaa aaatcaggtg gtcacttgta tcaccacatc catgaattgg attgcgttca
    11401 attccttatg gggggcatgc ctgaaactgt aaccatgaca ggtggaaatg tggcccatga
    11461 aggtgaacat ttcggtgatg aagatgatat gatttttgtc aatatggaat tttctaataa
    11521 gcgttttgcc ttgttagaat ggggttcagc ttatcgttgg ggtgaacatt atgtcttaat
    11581 ccaaggaagc aaaggtgcca tccgcttaga cttattcaac tgtaaaggaa ctcttaagct
    11641 agatgggcaa gaaagctatt tcttgattca cgaatcgcaa gaagaagatg atgatcggac
    11701 tcgtatctat catagtacag agatggatgg agcaattgct tatggtaaac caggtaaacg
    11761 tactccatta tggctatcat ctgtcattga taaagaaatg cgctatctgc atgagattat
    11821 ggaaggagct ccagtatcag aagaatttgc aaaacttttg acaggtgaag ctgccctaga
    11881 agcaattgct actgcagatg cttgtaccca gtctatgttt gaagatcgca aagtaaaatt
    11941 gtcagaaatt gtaaaataaa ttttggtatt ctcctattat aggtcgactt gctcctctga
    12001 aagtactttt agaggagctg tttgactttg ctagtttttg aaactgaaat ctattatact
    12061 acaaactatt gaaagcgttt taattttaag gtataataat ctcatagaaa taaagaaaag
    12121 gaggaaagag gatg
//
LOCUS       DAVBOU010000058        12058 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBOU010000058 DAVBOU010000000
VERSION     DAVBOU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.058"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ879_001837"
     CDS             complement(<1..207)
                     /locus_tag="VQ879_001837"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143946.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ879_001838"
     CDS             complement(275..916)
                     /locus_tag="VQ879_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143947.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ879_001839"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ879_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ879_001840"
     CDS             complement(3216..4115)
                     /locus_tag="VQ879_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3143948.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ879_001841"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ879_001841"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3143949.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ879_001842"
     CDS             complement(4747..5520)
                     /locus_tag="VQ879_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3143950.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ879_001843"
     CDS             complement(5825..6718)
                     /locus_tag="VQ879_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3143951.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ879_001844"
     CDS             complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ879_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3143952.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(7281..8495)
                     /locus_tag="VQ879_001845"
     CDS             complement(7281..8495)
                     /locus_tag="VQ879_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3143953.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(8651..8944)
                     /locus_tag="VQ879_001846"
     CDS             complement(8651..8944)
                     /locus_tag="VQ879_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143954.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9106..9558
                     /locus_tag="VQ879_001847"
     CDS             9106..9558
                     /locus_tag="VQ879_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3143955.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(9593..10981)
                     /locus_tag="VQ879_001848"
     CDS             complement(9593..10981)
                     /locus_tag="VQ879_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3143956.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            11047..12009
                     /locus_tag="VQ879_001849"
     CDS             11047..12009
                     /locus_tag="VQ879_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3143957.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         3442 a         2834 c         2200 g         3582 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaataaaa taataacagg acaaatcgat caggacagtc
     6841 aaatcgattt ctaacaatgt tttagaaaca gaggtgtact attctagttt caatctacta
     6901 taacatcgct tccgaatcca tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt
     6961 agactcgagt tcctactgat ttttgataga attcgtttgg attatgcagc caaaactttg
     7021 cgtcctttac gacgacgagc tgccaatacg cgacgaccat ttttagttga catacggtta
     7081 cggaatccgt gtttgcgcgc acgacgaagt ttacttggtt gataagtacg tttcacgatg
     7141 aatacctcct catagatttt gtattcgttt agccggctat aaagtgatca gttactaaac
     7201 atactttact attctatctg attctttcac ttttgtcaat agctctaggc aaatgtttcc
     7261 agctttttcg aatgcaagcc ctatctacga tactgtttca agaaacgagt catcttttct
     7321 tggatttggg ctaactcatc aacacgagga aggtaaacga tacggaagtg gtctggttcc
     7381 tgccagttaa agcctcgacc atgaaccaag agaacctttt cctgcttcaa gaaatcaagg
     7441 acaaactgct catcatcatc gatacggtac atattgcggt cgatttttgg gaagatatag
     7501 agccccgcct tgggtttaac ggcagacaaa cctggaatat cttgaatggc attatagatg
     7561 aaatttcttt gctcgtagat tcgtccacca ggaagaagca attcatcgac tgattggtga
     7621 ccccccaagg aagtttgtac gacttgttgg gccaaaacgt tagagcaaag gcgcatattg
     7681 gacagcatat tgagcccttc gatatagccc ttaacatgag tcttagggcc agacaagacc
     7741 atccaaccca cacggaaacc tgctatgcgg tgggattttg acagaccatt catgctgaca
     7801 cagaagacat ctggtgccaa gctcgccaca ggcgtatgca catgtccgtc cattaccatg
     7861 cggtcataga tttcatccgc aaagataatc aaatcgtttt gacgggcaat ctcaataatc
     7921 cccagcaaga gttccttagg ataaagggct ccagttgggt tatttggatt gataaggaca
     7981 attgccttgg tattggaagt gatttttgac ttgatatcgt caatatctgg gtaccattcc
     8041 acagcttcat cacagatata gtgaacggca tttcctccag ctaggctgac agccgccgtc
     8101 catagaggat agtctggcat tggcactaag acctcatccc cattgtccaa aagcccctgc
     8161 atggacatga caatcaactc actgacacca tttccaaggt aaatatcatc aatatctacg
     8221 tttgggaatt tcttcagctg gcaatactgc atgatggcct tacgggctga gaaaatccct
     8281 ttggagtcag aatagccttc actatcacgc gcattcataa tcaagtcatg aatgacctcg
     8341 tctggcgctg taaagccaaa ttctgctgga tttcctgtat tcagacgtaa aatcttttct
     8401 ccattcgctc gcatccgcat ggcttcttcc aatacaggac cacggatatc ataagcaaca
     8461 tgctctaact tactagactt gttatattct ttcatcttgt ttcctcaatt catcaggata
     8521 gtaacattat accactagaa agagaatgcg acaagtttac tgaaatgtgt tactagtttc
     8581 gtatagaaga aaaaccttgc taaaggcgag gttaagaacg tagagatagc aggtattttg
     8641 caaagacaca tcacatacca aaagataaac ctagaaaaag caagcctaga aaggagtcat
     8701 aaagaagatt aaacatgagg aaaagccccc atatcatcaa gtaatcccaa cgcccacttc
     8761 gttttgcaac tagaaataag attagatggt agagtacatg aaagactaaa aatccaataa
     8821 aacctggata aataagcggt accaaactct ctaattgcca gatcatgatc acttctacca
     8881 agactgaaac taggataatt ccataataca ggaaatttga tttttgaaaa gagtttttca
     8941 tcattctccc ttccttcact tctttcctgc tatcctttct tttattttat catatattta
     9001 tatagatttt aagccctaat attcttttga aaaatacttt ttttgcttta cttctatagt
     9061 gaaaaggttt acaattatag taagaaaatt tcaggaggtt tcattatggc acaacgttac
     9121 caaaatatca tggtcgcaat cgatggttct aaggaagcgg acttggcttt tgtcaaggga
     9181 gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg tacatgtcat tgacacacgc
     9241 gctctccaaa gcgtatccac ctttgatgct gaagtttacg aagaactcca agtcgacgct
     9301 gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg ctggggtagc agatgttcat
     9361 atcgtcattg aaatgggaaa tccaaagacc ctgctagcac gtactattcc agatgccgag
     9421 gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg cctttgaacg cctcttagtc
     9481 ggctcttcat ctgaatacat actccgccat gctaaggtcg atttgctggt tgtgagagaa
     9541 caagaaaaaa ccttataatc acaaagaaaa ggagccccta gctccttttt gtttacgatt
     9601 tatttctctc tttatggcgt tcgtaagcct tgagctggcg ctgcagttcc tttttaatag
     9661 caggttctgg agcatatttt tcttcccaat tatctggttt taagatttta tgggtcactg
     9721 gatcaaaatg agccttgcca tctggaaaaa ttttccccat attggcctga tggacaatat
     9781 caaaaatacg ttctgggtcc acccccatca agacaaaact gccgtaggtg aagtaaagcg
     9841 tgtcaatcaa ggcatccact tgccctatca aatcttgctg agcaggtgtc ttcttggcta
     9901 ctttacctgc tgccttatca agggcctgat gaagttgcga tacagcttga ccaaaatctt
     9961 cttcagaagg actggctgct cgaacaaact ccaccaattc ttctatttta aaaccagccc
    10021 tatgggttgc accctctaaa tcccaagctc gaggttcttc ttgggttcgt tcatccatca
    10081 tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg gctgacaaag actttttctg
    10141 aagacaaaac accaaaatgt tccaaggcct tgtggatccc atcttgttga ttgctagtgg
    10201 taatgtgctt ggcagcttcc ttgacactgc tactaccatt tcccatagcg accgacatac
    10261 cgacgccagc cagcatttca aggtcattat ctgagtcacc aaaagccatg acttggttga
    10321 ggtcaaagcc atattctttc ccaactcggc gaatgccttc taatttagaa tttccctgat
    10381 tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt caagtcttca aaatcagctg
    10441 ccgccttctc agattcttct ggtgtcatca gcatcaaaac ttggtagata ggctgattca
    10501 tcaggtgaag caggtcctct tccttttggg gaacaacctt gctgaccatg cgattaaaag
    10561 actgactcac cgtccgagtt aaaacagagg gaacgaagcg actaattcgt tgggaaaaag
    10621 aacccagacc aaaggacatg attttagaac ccaacatggc atccttggtc cctagagcaa
    10681 tctccgtgcc ctctttttta gcatagctaa ttagatggcg caaatgtaac ttggaaatag
    10741 ggctcgtgaa caagactctg tctttactaa agatatactg gccattatag gttaccgcaa
    10801 aatccagatc caaatcgtcc atcaattcct taacaaaaaa aggtcctcgt cctgtcgcta
    10861 cgccaactag taccccttgt tctttgacaa tcttaatcgc gtccttagtg gatttcaaaa
    10921 cactcttgcg attgttgacc aaggttccat cgatatcaaa aaaaacagct ttgacttcca
    10981 tcctattcca atctcccctt ttgtgataca atgattatac cacatttcag aaagagttag
    11041 taaatcatgc ctaagaaaat ccttgtttta catacgggtg gaactatttc catgcaggcc
    11101 gatgcttctg gcgctgttgt gacgagttca gataatccca tgaaccatgt gtccaaccca
    11161 cttgaaggaa tccaagtcca cgccttggac ttttttaacc ttccaagtcc ccatatcaaa
    11221 cccaaacata tgctggtcct ctaccagaaa attaaagagg aagcagataa ctacgatgga
    11281 gtggtgatca cacacggaac cgatacttta gaggaaacag cctatttcct tgataccatg
    11341 gaagttcccc atatgcctat cgttctaaca ggagccatgc gtagctccaa tgagctcggt
    11401 agtgatggtg tttataatta cctaagtgct ttacgagtgg ccagcgatga cagggctgct
    11461 gacaaaggag ttttggtcgt tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa
    11521 acacatacga ctaatgtcag caccttccag actccaacac atggccccct cggtctcatc
    11581 atgaaacagg aaatcctcta cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat
    11641 cacatacaag gtttagtccc tatcatctcg gcttatgctg gtatgacaga tgagctgatt
    11701 gatatgctgg atttagaaca cttggacggt ttgattatcc aagccttcgg agctggtaat
    11761 attcccaaag aaacggctca aaaattagaa agccttctgc aaaaaggaat cccagtcgct
    11821 ctggtatcac gatgctttaa cggtattgcc gagcctgttt atgcctacca gggtgggggc
    11881 gtacagttgc aaaaagcagg cgttttcttt gttaaagaac tcaacgccca aaaagctcgc
    11941 ttgaaactcc tcatcgccct caatgccgga ctaacaggac aggctttgaa agactatatg
    12001 gaaggctaat actcttcgaa aatctctgca aaccacgtca gcgtcgcctt accgtatg
//
LOCUS       DAVBOU010000059        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBOU010000059 DAVBOU010000000
VERSION     DAVBOU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.059"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ879_001850"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ879_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3143958.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ879_001851"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ879_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3143959.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ879_001852"
     CDS             complement(2411..2905)
                     /locus_tag="VQ879_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143960.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ879_001853"
     CDS             complement(2902..3366)
                     /locus_tag="VQ879_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3143961.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ879_001854"
     CDS             complement(3376..4710)
                     /locus_tag="VQ879_001854"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3143962.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ879_001855"
     CDS             complement(4721..5338)
                     /locus_tag="VQ879_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3143963.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ879_001856"
     CDS             complement(5386..8484)
                     /locus_tag="VQ879_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3143964.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ879_001857"
     CDS             complement(8577..9743)
                     /locus_tag="VQ879_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3143965.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ879_001858"
     CDS             complement(9751..10845)
                     /locus_tag="VQ879_001858"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3143966.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ879_001859"
     CDS             complement(11003..11656)
                     /locus_tag="VQ879_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3143967.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBOU010000060        11434 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBOU010000060 DAVBOU010000000
VERSION     DAVBOU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.060"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ879_001860"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ879_001860"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3143968.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ879_001861"
     CDS             complement(2224..3483)
                     /locus_tag="VQ879_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143969.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ879_001862"
     CDS             complement(3485..4186)
                     /locus_tag="VQ879_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143970.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ879_001863"
     CDS             complement(4170..5369)
                     /locus_tag="VQ879_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3143971.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ879_001864"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ879_001864"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3143972.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ879_001865"
     CDS             7176..7712
                     /locus_tag="VQ879_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3143973.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7763..7849
                     /locus_tag="VQ879_001866"
                     /pseudo
     CDS             7763..7849
                     /locus_tag="VQ879_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7918..8133)
                     /locus_tag="VQ879_001867"
     CDS             complement(7918..8133)
                     /locus_tag="VQ879_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3143974.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ879_001868"
     CDS             8231..8551
                     /locus_tag="VQ879_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143975.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ879_001869"
     CDS             complement(8582..8920)
                     /locus_tag="VQ879_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143976.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ879_001870"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ879_001870"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3143977.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ879_001871"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ879_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3143978.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ879_001872"
     CDS             complement(10190..10978)
                     /locus_tag="VQ879_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3143979.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ879_001873"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ879_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3285 a         2510 c         2079 g         3560 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttactaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat attgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 tttcaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta tattgaaact agaatagtac acct
//
LOCUS       DAVBOU010000061        11265 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBOU010000061 DAVBOU010000000
VERSION     DAVBOU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.061"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="VQ879_001874"
     CDS             complement(391..1527)
                     /gene="dnaJ"
                     /locus_tag="VQ879_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3143980.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1732..2085)
                     /locus_tag="VQ879_001875"
     CDS             complement(1732..2085)
                     /locus_tag="VQ879_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143981.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2098..3921)
                     /gene="dnaK"
                     /locus_tag="VQ879_001876"
     CDS             complement(2098..3921)
                     /gene="dnaK"
                     /locus_tag="VQ879_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3143982.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4401..4925)
                     /gene="grpE"
                     /locus_tag="VQ879_001877"
     CDS             complement(4401..4925)
                     /gene="grpE"
                     /locus_tag="VQ879_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3143983.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4952..5986)
                     /gene="hrcA"
                     /locus_tag="VQ879_001878"
     CDS             complement(4952..5986)
                     /gene="hrcA"
                     /locus_tag="VQ879_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3143984.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6150..6659)
                     /locus_tag="VQ879_001879"
     CDS             complement(6150..6659)
                     /locus_tag="VQ879_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3143985.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7267..7567
                     /locus_tag="VQ879_001880"
                     /pseudo
     CDS             7267..7567
                     /locus_tag="VQ879_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7762..9600
                     /locus_tag="VQ879_001881"
     CDS             7762..9600
                     /locus_tag="VQ879_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3143986.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9613..11076
                     /locus_tag="VQ879_001882"
     CDS             9613..11076
                     /locus_tag="VQ879_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3143987.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11076..>11265
                     /locus_tag="VQ879_001883"
     CDS             11076..>11265
                     /locus_tag="VQ879_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3143988.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2206 c         2212 g         3412 t
ORIGIN      
        1 catggcaagc cgacgctgac gtggtttgaa gaaatttttg aagagtatca ttcaccattt
       61 cacaactaaa tcgaagactt tctgccgtaa tgaaaacacc tgaaacagct tggtttcagc
      121 tgtccggaaa ctttaagact taggttcaaa gtttaggtat ggaacttcga aggaggtcgc
      181 taccgtccgt cattacttag gaaagtctta aaaaatctat aaagtaaaaa gagcccgaca
      241 gctctttttg tttatactca atgaaaatca aaaagcaaac taggaaacta gccacgggct
      301 gctcaaaaca ctgttttgag gttgtagata cgactcacat atatacggca aggcaacgct
      361 gacgtggttt gaagagattt tcgaagagta ttattctcca tcaaaggcat cttttatatg
      421 gtcaaagaag ccttttttct ttggatttac tttcaagtca ccagcagtcg cgaattcttt
      481 caaggctact ttttggcggt cgttcaagcc tgtcggtgtt acgacattaa cagtaacgta
      541 ttggtcacca actgcaccgc cacgaaggct cggtgccccc ttactacgta ggcggaattt
      601 cttaccagtc tgagttccct ctggaataac caattcaaca tcaccgtgaa cagttggaat
      661 atctactgta tcaccaagag ccgcttggac aaagttgagg ttgagattgt agaagatagt
      721 cgttccttca cgttcaaact tgtcgctagc ttctacagaa actactacat acaagtcacc
      781 ataaggtcca ccgttaaagc ctgcttcacc ttgaccagcg aggcgaattt gttgacctgt
      841 ttccacacca gcagggattt tcacatgtac gctatgagct tgtttctcat gacctgttcc
      901 atgacaggtt gtacatggat atttgatttc ttttcctcga ccgtgacaga catcacaggt
      961 tacttggcga cgcatcatac caagaggagt ctgcgtatcg acgttaatga caccagcgcc
     1021 atgacagcgt ccacaagtga ctggacttgt ccctggctta gcaccagagc cattacatgt
     1081 acgacagcca gcttcacgat gatacttaac ttccttctca gttccgaaga tagcttcttc
     1141 aaatgtcaaa ttgacacgat actggagatc atctccttgg cgaggagcgt ttggattgcg
     1201 cgaagaaccg cctccgccga agaaacttga gaaaatatcc tcaaaaccac cgaagccacc
     1261 tgccccattg aaaccaccga aaccaccagc tccaccaaaa ccaccattgg cgcctgcagc
     1321 accatactgg tcataggcag cacgtttttg gtcgtcactc aaagtctcat aggcttcttg
     1381 aacttccttg tacttgtcct cagcaccagg ctccttgttg atatctgggt gatatttttt
     1441 ggaaagctta cgataagcct ttttgatctc gtctgccgaa gcgttttttg acacccccag
     1501 acgatcataa aattcagtat tgttcataca agataccaag accgtaaaat tcgactgaaa
     1561 aataggaaat ctgacgctgg agcgacgctc ctagacagat ttctcttttt tccgagaatt
     1621 taggtcgggt tcaattcctt tcttttatat tgatgagata atactccagc cactcggccc
     1681 tatccctttt taccgaaaaa cagaggctgg gttgcaacct ctgtggttag attattcatt
     1741 tgaaataaaa atggttgtat tatctctagt agtaatcttc aaagaccttt tagctaaatc
     1801 aaactcaaat ttattatagt gtgggtcttg tgttttatat aggtgtaact cctgacatat
     1861 atgatccgaa aagtaaatca taacatcttt aaacacagaa gtgtagtcat atttactctt
     1921 accaacagct acttctgtaa attctttata aatgacattt ccatttcttt ccacagtcac
     1981 cagcatttct gttggattat aatccaaatt aaataattct tcaaaaaact ttatcttttc
     2041 atgataatct gcaatgtcag aaagattatt tttattaaca ctcataacac tagcccctta
     2101 tttttccgta aactctccgt ctacgacgtc atcgcctgcg tttcctgttg cttgtgcgcc
     2161 ttctgctcct tcttgagctt gttgcgctgc tgcggcttgt tcgtagagtt taacagcaag
     2221 tccttgagct ttttcgttca atgcttcaag tttcgctttc atgtcgtcca agttgttgtc
     2281 ttcttgagct ttcttaaggt catcaagggc agcttgggca gcgtcacgtt ctgcgtcgaa
     2341 gcctttacct tcagtttcct tgattgtctt ttcagtcgca aagattgctt ggtctacttc
     2401 attacgaagg tctacttctt ctttacgttt cttatcggct tcagcgtttg cttctgcatc
     2461 tttcatcatg cggtcgattt cttcgtcagt caaacctgag ttcgattgga tgacaatagt
     2521 ttgttctttt tgagttccaa ggtctttggc cttaacagac acgataccgt tcttgtcgat
     2581 gtcaaatgtt acttcgattt gaggaattcc acgaggtgca gctgggatat cagtcaattg
     2641 gaagcgtcca agagtcttgt tatctgctgc cattgggcgt tcaccttgaa gaacgtggat
     2701 atcaacggct ggttggttgt ctgctgctgt tgagaagact tgtgatttag atgttgggat
     2761 tgtagtgttg cgatcgataa gttttgtaaa tactccaccc attgtttcga taccaagtga
     2821 caatggcgtt acatcaagaa ggacaacgtc cttgacatca ccagtaatca caccaccttg
     2881 gatagccgca cccatagcaa ctacttcatc agggtttact gatttgtttg gttctttacc
     2941 agtttcagct ttaacagctt caacaacggc agggatacga gttgaaccac caacaaggat
     3001 aacttcgtcg atttctgaca agctcaaacc tgcatctgaa agggcttgac gaactggaac
     3061 ttttgtacgt tcaacaaggt cacgagtcaa atcatcaaat ttcgcacgag tcaaagtcat
     3121 ttccaagtga agaggtccag cctcacctgc agtgataaat ggcaagctga tttgtgttga
     3181 agttacacca gaaaggtctt tcttcgcttt ttcagccgca tctttcaaac gttgcattgc
     3241 catcttgtca gtagacaagt cgataccgtt ttctttcttg aattctgcta ccaagtggtc
     3301 aatgattttt tggtcaaagt cgtcaccacc aagtttgttg tcccctgcag ttgacaatac
     3361 gtcgaagaca ccgtcaccca attcaaggat agagacgtcg aatgtaccac caccaaggtc
     3421 aaataccaag attttttctt ctttatcagt cttgtccaaa ccataagcaa gagctgctgc
     3481 agttggttcg ttaacaatac gttctacttc aagaccagca attttaccag cgtcttttgt
     3541 tgcttgacgt tgagcgtcgt tgaagtaagc cggaactgtg ataacagctt tggttacttt
     3601 ctcaccaagg tagtcttcag cgtagccttt caagtattga aggatcatag ctgagatttc
     3661 ttgtggagtg tattcttttc catttgcaga aactttttca gaagttccca tcttagattt
     3721 gatagagata actgtatctg ggtttgtgac tgcttgacgt tttgcagcat caccaacgat
     3781 gatttctccg tttttgaatg agactacaga tggagttgtg cggtttcctt ctgggtttgc
     3841 gatgattttg ctttcagttc cttcaagaac tgcaactgct gagtttgttg tacctaagtc
     3901 aataccgata attttagaca tgtgtttttc tccttgttag ttaattttct atttttcttt
     3961 ttgatactct tcttaagtgg cgacgccgtc agagcttgac ttcgtcaatc tctttgacta
     4021 aactttgagc ctaaggtctc aaaatttgcg caaatagcgc cacggcgaag agtatcgtgt
     4081 ttggttcgct tcgctcacta ttacaaagcc aaacatattt tatctttctt catagtttat
     4141 tgtcgtttcg gacaagtttt ctattatgta aattgcgaca cgaagagtcg aaatcgattt
     4201 tatttcgacg acgagttagt aaggaagcta ggcaaacgcc atagcgattg ccgttttctg
     4261 acgagttgct ttagctaccg tcagaattgc cgaatcgaac acgccctaag ctctgagtaa
     4321 aaaagataga ttttcttgtg ttcatcgaac acttcgttaa tctcctattt ttactgcgag
     4381 ctttttacgg gctttgtatc ttagttatac accactacca ttgctgggcg taggatgcgg
     4441 tcatggagtt tgtagccttt ttgaaagact tgagcgatgg tatctactgg gtgttcatcg
     4501 tctgctggga gagtttggat ggccatatgg tagttatggt caaattcgcc atctgctgcg
     4561 atttcttcaa ttccttcttc tttcaaagcg tgaatcaagc tttcttgcac catccccaag
     4621 cccttcttca catcatctgt caaaccttca actgcaagtg cacgctcaag gttgtcaaga
     4681 gatggtaaga ttgcttttgc caagtcctgg ctacgataac gttgcaagtt ttgacgttct
     4741 tcattggcac ggcgttggat attttgcatt tctgcatgag cgcgaagata tttgttttcg
     4801 aactcatctg cacgttcatt tgccaagtcc aactcagact tttcaggagt tgtttcttca
     4861 gctgtttcca caacttcctc ttcttgaact tcttctactt cttcattttt tatatcttgg
     4921 gccatgttcg cctcctttaa tgatttcaat cttaatgtac ttcgtaatga ttactgctga
     4981 ggtagcggta aaaatctgtc aacttcatgg tcaaaacacg gttgaccaca ttgatttgat
     5041 tgattagctg ttggtaatcc agattaactg gaccgataat ggctagaatt ccaactcccc
     5101 gataaggaat gaggaactta ctactaatca ccgctaggtc agctaaacag gactcttgac
     5161 cgtctgcaat acgaacattt tgcatctgat cctcacgcaa cccctcacga atctccaagg
     5221 ccaccttttg cggttggtca aagaactgat aggctgctag attggcaaaa ttcaagagat
     5281 tgaccttgcc cgccatcaca atgttttcgt tgaacatttc cttaaagatg tgttcaaaga
     5341 gatcgatgac attatccgtt gttgtaaagt aacgctggat aatctgcgga atctccgtcc
     5401 gaatcttgta gtgaatatct aaaacggtgt gaccgaggaa acgttcctga atgatgctct
     5461 tcagtttcag caaatcctcc tgcaagaagt tccttggaat cagaaactga ctagtaaccg
     5521 ttcgcgactc gtctagggta aataccgcca aggctgtatg ttgccccaaa acaacgatat
     5581 caaaggctgt caaacgttgc ctgctcggct caacatccag tgccactacc gtacagccac
     5641 tcaggtctgt tagcaagtta gcagcctctt gcagaatatc ctccaatttg aagaattcct
     5701 gatcaaaggc tttgacaatc tcatatacct cattttcagc cagccggtga aaatccagtg
     5761 agtgtttcac atagtactga aaaccagcaa cacttggcat ccgaccgctt gaagtatgag
     5821 ccttctcaag caacccttgt ttttctagtt ccgccatgtc attacgaatg gttgcactgc
     5881 tagagttaat agactcttgc aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga
     5941 tgtcaataat cagatttaaa atatcctgct gacgctctgt aaccatctca tcactcctct
     6001 ctgtctgatc aattagcact caatgcatcc aagtgctaac ttatgattct attatacacc
     6061 cttagaagag aatgtcaaga caaaaactca aaaaattagc actcttttat caagagtgct
     6121 aaaaatcaat ctgaagacct agaaccttgc tattcatcta ctcggtattt cctttttagt
     6181 ctgaaataac catgaattag ataagaaatc agaaaagcat ataaaacaaa aataagaaag
     6241 aaagacatag aaagatcctc tctaaacaaa ctcgtacaaa caacaagacc acctaagaaa
     6301 gtagctgtac aggaacgaag tctagatcgc ataacttccc atttgagccc cttactcata
     6361 tagacttgat cctctggaag taaatcagaa gacgatttac gaagaatcga acaagaacct
     6421 gctcctatca attcccaacc tctatctcta aaatcttgca gttcatgctt atatttttta
     6481 agaaatctag aatcatagat acggtagatg acatcgtctg gttgacattg gtcaaaatag
     6541 aacaaaccaa aacgactcgt tctatacctc caacctttca aatgcatctc atgtaaatat
     6601 tcttctttct tgtccaaatc aacaatggtg aaaatccgaa attctactct gctattcatt
     6661 gtcttacccc aaaattagaa aacatgccta gcgttattta ttagataatt ctttccactt
     6721 ttgactcaat ctccaaaaaa tataagaaat ctgaatcgca aaaactatca ataaaaccca
     6781 atctattatg aaaatcaaaa acacttccca actgaaagaa ctacctccag tgacaaactt
     6841 tgagaaaaac ggtagtagag ctaaaaagag aagcaaaata ggaagcatcc gcattgttaa
     6901 aatccgtttg gcataaaaaa atctttattt aaacgaaaat attatggcaa aatttacgcc
     6961 agtttttgaa cggctgatgt agatatttta tactttcaaa atgtttaaat gtgattattt
     7021 atttttgaaa aatagctcac cagcccgact gaaagtgctt atagaatgat aataagtcgc
     7081 ctgccgaaaa cagcggaaaa tagcggtgtt atgcggagat aatctgacgc gatgcgaaag
     7141 tatattgcat acttattttc aacaatttag cagagtattt ttataagtgt gatataatag
     7201 aagtataatt tgttctgata gtttatttta tggagaagta gatttttaga atgcggaggg
     7261 ttcaatatgg ttgagtttat aaagtctaag aaagaaatga gtgaggagga tattaaagca
     7321 aatttcatca ctcctgctat tgtatccaaa ggatggaaaa atggtgagca tatcgcttac
     7381 gaagaatact tcactgatgg tcgaattgag gttagaggag ataaggctcg tcgtaaagaa
     7441 ggaaaaaaat cagactattc actgtattac caatttggaa ctcgaattgc aattgttgag
     7501 gcaaaggata ataaacacag cgttcgagca ggattacaac aagctattga atatggagag
     7561 attttagatg ttccatttgt ttattcttca aatggtgatg gctttattga acacgaccgt
     7621 atcacgagag aagaacgtga gctggagtta gacgaattcc ctactcgtga agaattattt
     7681 tctcgtatga cgaaggaaaa aggattgacg tacgaaatta cagaagctat ctaaactcca
     7741 tactatacag acgccttctc aatgaaaacg ccacgctatt atcagcaaat agctatcaac
     7801 cgtactattg aaacagttgc cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga
     7861 acggggaaaa cgttcatggc ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct
     7921 aaacgagttt tattcttagc ggatagaaac atcttagtag accaaacgat ggctgaagac
     7981 tttaagccat tcgaaaaggt aatgacgaaa attacaccaa aacttttgac tgctcctgaa
     8041 aaattaaatt cttttgaaat ttatctaggg ctttatcagc aactaactgg tgaagatgga
     8101 actgaaacac attatcaaaa atttgacaaa gacttctttg atttaatcgt aattgatgaa
     8161 gcgcaccgtg gttcagctaa ggaaaacagt aactggcgta agataattga ttatttcagt
     8221 tctgcgacac agattgggat gaccgctact cctaaagaaa ccaagaatgc ttccaatacg
     8281 gaatactttg gtgagccaat ctatacttat agtttaaaac agggaatcga ggatggtttt
     8341 ttggctccat atcgtgttat gagggttaat ttagatgtgg atgtggatgg ttatcgtcca
     8401 gaaactggaa aagttgatac taacggacaa ttaatagaag ataggtacta cggcaggaaa
     8461 gattttgata aaaccattgt cattgatgat agaacgcaaa gagttgccaa gtttgtttct
     8521 gattatatga agcaaagcaa tgcacgattt gataaaacaa ttgttttttg tgttgatatt
     8581 gaccatgccg agcgaatgcg tgctgcactt gtaaaagaga atctagactt agtccaagaa
     8641 gactatcgtt atgtcatgca agtaactggt gacaacgctg aaggaaaagc tcaactggat
     8701 aactttatgg atgtcaattc taattttccc gctattgtaa caacgtctaa attattaacg
     8761 acaggagtta atgctaaaac atgtcgtttg attgttttag actctaatat ccaatccatg
     8821 actgaattta aacaaattat tggtcgtggc acacgtcttt atcctcaaaa ggggaaagaa
     8881 ttttttacga ttattgattt tcgaaatgtt accaatttgt ttgctgaccc tgattttgat
     8941 ggtgagccag tgaaggtgct ggaaacaggt gcgaaaacag tcagtggttc cacgcccggt
     9001 ttcgtagatg aggaaggtga cccagtagaa aaatatatcg ttacagacaa gcaggttacc
     9061 attcttaatt ctactgttca agtattggat gaaaacggga aactgattac cgaaagcctg
     9121 accgactaca ctcggaagaa tatcttaggt agctacgcca ctttgaacga ttttatcaca
     9181 gtttggcata cggcggataa aaagaagctt atcttagacg aactttataa aaaaggagtt
     9241 tatctagatg ctattcgaga gtcggaggga atatcagaac aagaaatcga tgattttgat
     9301 ttactcctaa aacttgccta tggtcaaaaa gaattaacca aaacggaacg tatcaataaa
     9361 ctcaaacaaa gcggatattt atataaatat agtgaggaag cgcgtgctgt tttggaaatt
     9421 ttactgaaca aatacatgga taaaggtatt ggagaactcg aaagcattga aacattaaaa
     9481 cttccagaat ttcagatata tggtggaacc ttcaaaatca tcaatactta ttttggagat
     9541 aaaaaacgat atttacaagc aattaaagaa ttggagcaag agctatttac agtagcttaa
     9601 tgaaaggaaa gtatgtcaat tacatcattt gtaaaaagaa ttcaagatat cactcgaaac
     9661 gatgctggtg ttaatggtga tgctcaacgt attgagcaaa tgtcttggtt attattctta
     9721 aaaatttatg atagccgtga aatggtttgg gaattagaag aagacgagta tgagtcaatt
     9781 atcccagagg aattaaaatg gcgaaattgg gctcatgctc aaaatgggga acgggtattg
     9841 acaggcgatg aattacttga ttttgtcaat aacaagttat tcaaagagtt gaaagagctt
     9901 gaaataactt caaatatgcc tattcgaaaa acgattgtta aatcagcttt tgaagatgcg
     9961 aacaactata tgaaaaatgg cgtcttgtta cgccaagtca tcaatgttat tgatgaagtt
    10021 gatttcaata gccctgaaga tcgtcattcg tttaatgata tttacgaaaa aattcttaaa
    10081 gatattcaaa atgctgggaa ctcaggagaa ttttatacgc cacgtgcagc gactgatttt
    10141 attgccgaag ttcttgaccc aaaacttgga gaatcaatgg cagaccttgc ttgcggaaca
    10201 ggaggcttct tgacttcgac tctgaaccgt ttaagtagtc aacgtaaaac tagtgaagat
    10261 accaaaaaat ataatacagc tgtttttggt attgaaaaga aagcatttcc tcatctttta
    10321 gcagttacaa atctgtttct tcacgaaatt gatgacccta aaattgttca tggaaatact
    10381 ttggagaaaa atgttcgtga atatacggat gatgaaaaat ttgacattat tatgatgaat
    10441 ccaccttttg gagggtcaga attagaaaca ataaaaaata actttccagc agaattacgg
    10501 agttctgaaa cagctgattt atttatggct gtcattatgt atcgtttgaa agaaaatggt
    10561 cgtgttggag ttattttacc tgatggtttt ctatttggtg aaggtgtaaa aactcgcttg
    10621 aaacaaaaac tggtagatga gttcaacttg catacgatta ttaggttgcc tcatagtgtc
    10681 tttgcaccgt atacaggaat ccatacgaac attcttttct ttgataaaac aaagaaaaca
    10741 gaagaaactt ggttttatcg tttagatatg ccagatggtt ataaaaattt ctcgaaaact
    10801 aagccgatga agtcagaaca cttcaatcct gttcgtgact ggtgggaaaa tcgtgaagag
    10861 attctggaag gtaagttcta caaatctaaa tcatttacac ctagtgaatt ggctgagttg
    10921 aattataatt tagaccagtg tggttttcca aaagaggaag aggaaatctt aaatcccttt
    10981 gagttgattc agaattatca agcggaaaga gcaactttaa atcataagat tgataatgta
    11041 ttagctgata ttttgcagtt gttggaggac aaataatgac accagaacaa cttaaagcaa
    11101 gtattctcca aagagcgatg gaagggaaat tagtgccgca aaatcccaat gacgaacctg
    11161 caagtgaatt attaaagaga attaaagctg aaaaagaaaa acttatcagt gaaggaaaaa
    11221 tcaaacgaga taaaaaggaa actgagatat ttcgtggtga tgatg
//
LOCUS       DAVBOU010000062        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBOU010000062 DAVBOU010000000
VERSION     DAVBOU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.062"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ879_001884"
     CDS             <1..116
                     /locus_tag="VQ879_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3143989.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ879_001885"
     CDS             140..1063
                     /locus_tag="VQ879_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3143990.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ879_001886"
     CDS             1145..2773
                     /locus_tag="VQ879_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3143991.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ879_001887"
     CDS             2882..3832
                     /locus_tag="VQ879_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143992.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ879_001888"
     CDS             3849..4700
                     /locus_tag="VQ879_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3143993.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ879_001889"
     CDS             4713..6695
                     /locus_tag="VQ879_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3143994.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ879_001890"
     CDS             6705..8114
                     /locus_tag="VQ879_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3143995.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGFTEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ879_001891"
     CDS             8119..8607
                     /locus_tag="VQ879_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3143996.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ879_001892"
     CDS             8895..9302
                     /locus_tag="VQ879_001892"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3143997.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ879_001893"
     CDS             9334..10251
                     /locus_tag="VQ879_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3143998.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ879_001894"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ879_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ879_001895"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ879_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3143999.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3692 a         1665 c         2115 g         3613 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta tagaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggttttac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBOU010000063        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBOU010000063 DAVBOU010000000
VERSION     DAVBOU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.063"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ879_001896"
     CDS             complement(128..1759)
                     /locus_tag="VQ879_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3144000.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ879_001897"
     CDS             2052..6992
                     /locus_tag="VQ879_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3144001.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ879_001898"
     CDS             7082..8278
                     /locus_tag="VQ879_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3144002.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ879_001899"
     CDS             8414..8941
                     /locus_tag="VQ879_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3144003.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ879_001900"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ879_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3144004.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ879_001901"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ879_001901"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3144005.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ879_001902"
     CDS             complement(10847..10966)
                     /locus_tag="VQ879_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3144006.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBOU010000064        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBOU010000064 DAVBOU010000000
VERSION     DAVBOU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.064"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ879_001903"
     CDS             complement(117..1541)
                     /locus_tag="VQ879_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3144007.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ879_001904"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ879_001904"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3144008.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ879_001905"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ879_001905"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3144009.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ879_001906"
     CDS             complement(6527..7705)
                     /locus_tag="VQ879_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3144010.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ879_001907"
     CDS             complement(7785..8648)
                     /locus_tag="VQ879_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3144011.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ879_001908"
     CDS             complement(8651..10552)
                     /locus_tag="VQ879_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3144012.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3220 a         2371 c         1916 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBOU010000065        10497 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBOU010000065 DAVBOU010000000
VERSION     DAVBOU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.065"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            162..374
                     /locus_tag="VQ879_001909"
                     /pseudo
     CDS             162..374
                     /locus_tag="VQ879_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            274..720
                     /locus_tag="VQ879_001910"
     CDS             274..720
                     /locus_tag="VQ879_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3144013.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(858..2162)
                     /gene="eno"
                     /locus_tag="VQ879_001911"
     CDS             complement(858..2162)
                     /gene="eno"
                     /locus_tag="VQ879_001911"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3144014.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2326..2772
                     /locus_tag="VQ879_001912"
     CDS             2326..2772
                     /locus_tag="VQ879_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3144015.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2769..3884)
                     /locus_tag="VQ879_001913"
                     /pseudo
     CDS             complement(2769..3884)
                     /locus_tag="VQ879_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(3998..4222)
                     /locus_tag="VQ879_001914"
     CDS             complement(3998..4222)
                     /locus_tag="VQ879_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3144016.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4167..4538)
                     /locus_tag="VQ879_001915"
     CDS             complement(4167..4538)
                     /locus_tag="VQ879_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3144017.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4597..6030)
                     /gene="glgA"
                     /locus_tag="VQ879_001916"
     CDS             complement(4597..6030)
                     /gene="glgA"
                     /locus_tag="VQ879_001916"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3144018.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6027..7166)
                     /gene="glgD"
                     /locus_tag="VQ879_001917"
     CDS             complement(6027..7166)
                     /gene="glgD"
                     /locus_tag="VQ879_001917"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3144019.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7156..8298)
                     /locus_tag="VQ879_001918"
     CDS             complement(7156..8298)
                     /locus_tag="VQ879_001918"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3144020.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8288..10216)
                     /gene="glgB"
                     /locus_tag="VQ879_001919"
     CDS             complement(8288..10216)
                     /gene="glgB"
                     /locus_tag="VQ879_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3144021.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     SVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3196 a         2298 c         1847 g         3156 t
ORIGIN      
        1 ttttgaagct tggtttcaga aatttctctt accaacatta accgcaccat tggttattat
       61 attaaaacga agtaagaata ggacaaatcg atcaggacag taaaatctaa ttctaacaat
      121 gttttagaag tagaggtgta ctattctagt ttcaatctac tatattaatg gacaatgcaa
      181 gattccatag aatggggaag ctagaactct tgtgtgaaga gtttgggcat aaacttttac
      241 ctcttcctcc ctactcgcct gagtacaatc ttattgagaa aacatgggct catatcaaaa
      301 agcacctcaa aagggtatta ccaagttgca atacctttta tgaggctctt ttgtcttgtt
      361 cttgtttcaa ttgactatat aaattgtcta agcgaaacaa ccgataagaa ttggcacaaa
      421 agcgaccgta tttttgttac caatacagga aaaccagttc atagttctat cttgagcaag
      481 tctctccagc gagcaaacga acgccttaaa aaaccaattc ccaaacatct gtcccctcac
      541 atcttcagac acaccactat tagcatctta tcagaaaata aaattccttt aaaaacaatc
      601 acggacaggg ttggtcattc cgactctgaa gtcactactt ccatctacac ccacgtcaca
      661 aagaacatga aagatgaagc aatcaatgta ctggataaag ttatgaaaaa gattttttaa
      721 aaagttttgt cccttttttg tcctctaaat acaaaaatag cccttcggat aaaatccgag
      781 gggctagaaa cgttgttaaa tcaacggccg aacttttgaa tttcatggtt cgggataaaa
      841 tagttcactg aactatttta ttttttaagg ttgtagaatg atttcaatcc acgatattca
      901 gctacttcac caagttggtc ttcgatacga agcaattggt tgtatttagc gatgcggtct
      961 gtacgtgaaa gtgaaccagt cttgatttgt cctgcgttag ttgcaactgc aatatcagcg
     1021 attgttgaat cttcagtttc acctgaacgg tgtgatacaa cagcagtgta accagcttct
     1081 ttagccattt cgatagcttc aaaagtttca gtaagagtac cgatttggtt aactttgata
     1141 aggattgagt tagcagcacc ttcttggata ccacgtgcaa ggtagtcagt gtttgttacg
     1201 aagaagtcgt caccaacaag ttgtactttc ttaccaagac gttcagtaag agctttccaa
     1261 ccatcccagt cgttttcatc cataccatct tcaatagtga tgattgggta tttgttaacc
     1321 aattcttcaa ggtagtcgat ttgttctgca gatgtacgaa cagcagcacc ttcaccttca
     1381 aatttagtgt agtcgtaaac tttacgttct ttatcgtaga attctgatga agcacagtca
     1441 aatccgataa atacgtcttt acctggtaca tatccagcag cttcaatcgc agcaaggata
     1501 gtttcaacac catcttcagt tccttcgaaa cgaggagcga atccaccttc gtcacctacg
     1561 gcagtttcca aaccacgtga tttaaggatt ttcttaagag cgtggaagat ttcagcaccg
     1621 taacgaaggg cttctttaaa tgttggcgca ccaactggca agatcatgaa ctcttggaaa
     1681 gcgattggag cgtcagagtg agaaccaccg ttgatgatgt tcatcattgg agttggaaga
     1741 actttagtgt tgaatccacc aaggtagctg taaagtggga tttcaaggta gtcagcagca
     1801 gcacgagcta cagcgataga cacaccgagg attgcattcg cacccaattt acctttgtta
     1861 ggagtaccgt caagtgcgat catagcacgg tcaatagctt gttgatcacg tacatcgtag
     1921 ccaatgatag cttcagcaat gatgttgttt acgttgtcaa cagctttttg tgtaccaaga
     1981 ccaccgtaac gagatttgtc accgtcgcga agttcaactg cttcgtgttc accagtagaa
     2041 gctcctgatg gaaccatacc acgtccgaaa gcacctgatt cagtgtaaac ttctacttca
     2101 agtgttgggt taccgcgtga gtctaggact tcgcgagcgt aaacatcagt aataattgac
     2161 attttttact ctccttatga gttaaatttt ttacacctct ataatacctt aaaacccctc
     2221 ctttttcaag aaaaaacgtt atctttgtgc aacttttcct taactttata aagtaatcgc
     2281 tttcttttgt ctgttttatt ctaactttta tgatatactg ttttcatgac agatttatca
     2341 aaacaattac ttgaaaaagc tcatggtggg ttaaaaataa atccggatga gcaaagacgc
     2401 tatcttggta cttttgagga aagagttctt ggatatgtag atattgacac agcaaatagc
     2461 cctcagttag aaaaaggctt tttatttatt ttagaaaacc ttcaggaaaa agcagagcca
     2521 ctatttgtga agatttcacc aactatcgaa tttgataagc aagttttcta cttaaaagaa
     2581 gcaaaagaaa ctgatagtca agccaccata gtatctgaag agcatattac ttctcctttg
     2641 ggcctggtta ttcatagcaa tgcaccagtt caagtagaag aaaaagacct tcgacttgct
     2701 tttccaaaac tttgggaagt taaaaaggaa gaaccagcca aaacatcctt atggaagaaa
     2761 tggtttagct aaatcttgca catatttaat aagtgcccaa tattggcagc cgtgcgctcc
     2821 agatagagac tggcattttt caaactatct tctaaaggtt cacttttctc caaaatagaa
     2881 aagacagctt ggatattttc aaatggtagg ggaggtaaat cttcagcaag actaccgcaa
     2941 atagcaataa caggaactcc aacaggggtt ctttttgcaa cacctatagg cgctttccca
     3001 gcaaagcttt gactatcaag tcttccttct ccaacaacaa ccaagtcagc atctgaaact
     3061 ttcttatcaa agttgattaa gtccaagcag gtatcaattc cagacacgat acttgcctga
     3121 gcaaaggcac acaaaccacc agcaaggcct ccacctgctc ctgctccttt aatttctaat
     3181 gttgcaggtg agaatttttc ataaaaatct tggatcgcct gatctacgac tgcaaacata
     3241 gtcggatgta gacctttttg attgccaaaa gtgtaagtcg caccttgatg accacataag
     3301 ggactcacga catctgctag aatatgaatt tgaacacctt caggaatttt atagcaattt
     3361 tctgttgaaa cagaagctaa gtttaataag gattgatcgg aagcaggcaa gacatttcca
     3421 tccctatcat aaaattgata accttaacca gcagcaatcc ccagtcctcc atcattactg
     3481 gccgtgccac caacaccgat ataaatatct ttaatccctt tagaaatgag atggagaatc
     3541 aactctccaa taccacaagt ttggatttga agtggatttc gtttctctag cggaattttt
     3601 ccaagaccaa ccaagtcagc tacttcaaat agtgccagtt cccctttttg aaaatagcgc
     3661 atggcttctt tttgtccaga agggtctgtc acttggatcc atttttcttt taggtcaaga
     3721 gaatgtcgga tagcatctac agtaccttct cccccatcac caacagggca gaggagacat
     3781 tctacatctg ctatcgattg ttggaagcct ctttttattg cttcagctac ctgttgagct
     3841 gtcaagcttt ccttaaacga atccggtgca attacaatct tcatattttc cctcattcta
     3901 aacagtcaat caaaggaaga acttctaaaa aatccctctt gtcaacatga tgtggtattt
     3961 cttttttgag catttctttg gaacaaaagg cgattcctca ctccgccgac ttcaacatta
     4021 atagattatt gaccccatca ccgattgcca ccgttctttc tttagaaagt tttagtttct
     4081 ttctccattt ttccagagtt tcttttttga cctggggact tataatttgt ccaactaatt
     4141 ttcctgttaa aagaccttct ttgacttcaa gctggttggc agtgaaatag gcaataccaa
     4201 gggattttgc taatctctcc aactattggt gtaaatccac cagacaccag accaactagg
     4261 atgccattct tttggagaat agagatgaac tctgggacat ttagcgatag atgaattgag
     4321 ttgaagacgt tatcaaagac caaaatagga agaccttcca acaaggacac tctttttctt
     4381 aaactgcttt caaagaccaa ctctcctcgc attgctcgac ttgtaatctg cgaaatttcc
     4441 gcctcatgac ctgcctctct ccctaaaaga tcaatcactt cttctaggat taaggttcca
     4501 tctacatcca aaacacacaa gccttttact tgagacatca gttctcctct ctaaacagcc
     4561 taaaaatcgt atgaagtcat catacgattt tatctattaa ttaactaaac tatggtacaa
     4621 gtcaaggtat gacttgcagg ctgtatccca tgagaagtca ctctccatag cttgtttttg
     4681 taggtttctc caaatgtctg gatggtttct atacaagtcc aatgctgttt ggaaagtcca
     4741 atttaaccaa taaggagata gattgtcaaa gctaaagcca gtaccgcttc cttcgattgg
     4801 attgaaagcg cgaactgtat ctcgcaagcc tccaacttca tggaccaatg gcaaggttcc
     4861 ataacgcata gccatcattt gagacaagcc acacggttca aaacgacttg gcatgaggaa
     4921 gaggtcacaa gcagcgtaga tttcctgagc aagtttgaca tcaaaagtga tatttgttga
     4981 tagcttgtct gggtaaatct gagcaaacca tgagaaagct ccttcaaagg ctggatcgcc
     5041 agttcccaaa agaacaatct gaacatcttc ttgcaagata tggtgaagac tttcgaccac
     5101 cacatcaaaa cctttttgac gtgtcaaacg agaaacaatt cccaccagtg gaacgtctgc
     5161 tctaacaggc aagccaactc tttcttgcaa ttttgcctta tttttggctt tcccagacaa
     5221 atcttcctga ttgaaatgat agtctaaaag agcatccgtc tgaggattat aaagatcagc
     5281 atcaatccca ttcacgatac cagatacttt accagactcc attttaagaa tctgatccaa
     5341 attacatcca aactgactag tcataatttc atgagcatag ctaggtgaaa cagttgaaac
     5401 acggttcgca tagagaatac ctgccttcat ccagttcaga cagttgttcc atcgaagggt
     5461 gccatcagcg taacgttcaa agccaactcc aaacaaatca cccaacattc cttctgaaaa
     5521 ttgtccttgg aattctaaat tatgaatggt taaaactgtt tcaatgtcct cataggcttg
     5581 aatccaacgg tatttttcct tcaacaagaa aggaatcata gctgtatggt agtcatgaac
     5641 atggagaaga tcaggaataa agtcaatcct ttccatagcc tcaatggcag ccagttggaa
     5701 aaaggcaaag cgttctccgt catcaaaatc accgtaaaca tgaccacgga agaaataata
     5761 ttgattgtca ataaagtaga aggttacacc atttaatact gttttcttaa ttccacaata
     5821 ctgtctgcgc caaccaacgc tcacctcaaa atgaagcaca tcttcaatct gacttccaaa
     5881 tttagcctct accatatcat agtagggtaa aatcactgca acttcgtgcc cagcttttac
     5941 cagtgatttt ggaagagcgc caatgacgtc tcccaaacca cctgtttttg aaaagggtgc
     6001 accctctgct gctacaaata aaattttcat gaatgaatat cctctgttac tttagcacct
     6061 ttcttaacca caactggatg ttctgcagtt cctcgaatca caacaccagg ctcaacttca
     6121 acccctttgt ccaagatagc atattcgacc tgagcccctt ctccaataac aacacgaggg
     6181 aagagcaggc tatctttaac caagctatcc ttatggacat gaatattacg tgatagaaca
     6241 gaattagcta cttgaccttc aataatacta ccagaggcaa actgagaagt gcttacctta
     6301 gatgtattag catagtaagt tggctcttcg tttttgacct ttgtataaat cttttggttt
     6361 ggtgagaaaa gagaatagaa tttttgtgat tcaagcatat cgatattcgc ttgataataa
     6421 gatttaacag agtgaatatt ggctagatag cccgtgtact cgtaggcgaa agctccctct
     6481 tttacagcca aatcccgtaa aacatagcgc aatttctctg gatgttcttt tttagcttct
     6541 tcttccaagt gttcaatcaa ccaaggtgta tcaacgacaa agatatctgt agacatattg
     6601 aacgtttcag ctgttgactt gctatcaaag agtttatgag aaagaacatg gtctgtttca
     6661 tctacatcca agattgcatt tacttctgaa atatctttct tagctagttt tttataaact
     6721 acagtgatag gctcttttgt tgtactatgt aggtggaaaa cttggttcaa atcaatgtta
     6781 ataagaacat cgcagttgag ggcaaccgtt tggtttgagc cagaacgttt caaataagta
     6841 agaagctgtt ggtagtattc ttttccaact gtactacttt ctacacgggt attgtaaatt
     6901 cctagatagt aatggctaag aagggttgat aagccccact cgcgtcctga acgaatatgg
     6961 tcaaatactg agctgatatt atcctgctgg aaaataccaa agacactacg aacacctgca
     7021 ttagcaaggc ttgaaagtgg gaagtcaatc aaacgatatt tcccaccaaa tggcaaactt
     7081 gctactggac ggtggtccgt caatgtcgac atattgtgaa aaccaactgt atttcctaaa
     7141 atggcagaat atttatcaat cttcatctgt tgctaccccc actacttcat tatatcctac
     7201 aacttgtact tcatctgttc catcaatttc gacaccgtca gaaataatcg caccttcacc
     7261 aataatggca cgtttaatct tagctccttg accaatgata gctccactca tgataactga
     7321 atcaaggact tccgctcctt cgcgaacttg cgcgcctgtt gaaaggatag aatgtttaac
     7381 agttccatca acgaaacatc cgtctacaac taatgagtct tccacatgag catttgcccc
     7441 gaggaagttt ggtggtgaaa tcaagtttct tgagtaaatc ttccattgac ggttacgact
     7501 atccaaggca ttttctggag aaatatactc catgttcgct tcccaaagtg actcaatagt
     7561 accaacatct ttccaataac cactaaattc ataagcataa acactttcac ctgactcaag
     7621 gtaatttgga atgacatttt taccaaagtc tgacatgcca accttgctct tttcagcagc
     7681 gactaacata ttacgaaggc gttgccaatc aaaaatgtag attcccatag aagcttttgt
     7741 agatttaggt tgagctggtt tttcttcaaa ttcaacaata cgattgttag catctgtgtt
     7801 catgatacca aaacggcttg cttctttaag agggacgtct aaaactgcta ctgtcaagct
     7861 ggcattatta tccttatgag actggagcat atcatcatag tccattttgt agatgtggtc
     7921 cccagacaaa atcaagacat actcaggatt gacactgtcg atatagtcga tattttggta
     7981 aatagcgtga ctagtcccct caaaccaacg atttccttca cttgcagaat aaggttgaag
     8041 aatagagaca cctgaattaa taccgtctag tccccagctt gaaccattcc caatatggtt
     8101 gttgagagca agtggttgat actgtgtaac gaccccaaca ttatgaatcc ctgagttggc
     8161 acagtttgat agggcaaagt caatgatacg gtagcgccca ccaaattgca cagctggttt
     8221 tgcgatgctt tgagtgagtt taccgagacg agttccttgc ccaccagcaa gaatcaaagc
     8281 taacatttca tttttcattt tctactcctt tttggttttt atttgtgacg gttttagtag
     8341 atttcaagcg acgtttgatt ttccatacac ttgctcccat agccggtaga gtaaaggtta
     8401 aggtctgctc ataatctttc catagtcctt cttgcgtttg aacagtttga ttatgttctt
     8461 tccaaacgcc tccccactct tccaactcag tattccatac ttcttcgtaa attcctgcaa
     8521 cgggtagtcc gattgtaaaa tctttccgct caacaggtac catattaaag atacagacta
     8581 acatttctcc ctttttaccc ttacgaataa aggaaagaac actctggtct cgattatccg
     8641 catcaatgat ttcaatacca tcatagctgg tatcaatttc ccacagacag cgatgatctt
     8701 tgtaaaactg gtttagctga gaagcgaaat acttcatctt agcattcatt gggtcttcta
     8761 ggttagacca ttccaactgt tcttcagatt tccattctag gaattgaccg tattcgctac
     8821 ccatgaagag caatttctta ccagggtgac aaatttggta cgtatagaga ttgcgcaagc
     8881 ctgcgaattg attgtaacga tctccccaca tcttatgcat catactcttc ttgccatgaa
     8941 ccacttcatc gtgcgagaat ggcaagagat aattctcctt gaaaacatac ataaagctga
     9001 aagtcaccag gttaaagtca tatttacgat aaatcggatc ttcttcgtag aaacggagga
     9061 tatcattcat ccagcccatg ttccatttgt agtcaaatcc tagactacca atctctttca
     9121 ttcccgtaat cttggtcgca gacgaacttt cttctgcaat catcatcaca tctggatatt
     9181 ctaacttaat aacttcattc aagcgttgaa gaaaataata accttcatag ttgagatttc
     9241 cgccatcttt attaggtgtc catggagcat tatcatagtc caaatagagc atgttgctaa
     9301 cagcatccac acgaatacca tccaaatgat agacatcaat ccaatgctta atgcaagaaa
     9361 ttaagaagga ctggacttca ttttttccaa ggtcaaaatt aagggcaccc caaccatggt
     9421 tatgagcctt attatggtct tggtattcaa aagtcggtgt cccatcataa taggctaagg
     9481 catcatcgtt gatggtaaag tgacctggta cccagtccac aataacccca atattatggg
     9541 tatgacactc ctcgacaaaa tcttgaaact cctctggtct gccataagca tgctctaaag
     9601 cgaagtaacc cataagctga tacccccaac tcaagcccaa aggatgggac atcaagggca
     9661 taaactcaat atgagtatag ttcatttcaa cgagataagg aatgagttca tccttgagct
     9721 gggcaaaact ataaggactg ccatcagaat ttcttttcca tgatccagcg tgaacttcat
     9781 aaatattgac aggacgctct tcaaagcccc aacgttttct tcgtgccagc caaagtccat
     9841 ccttccattt cttctcagga agctctgtta agattgcccc tgttcctgga cgagcctcat
     9901 acctgacaga aaaagggtca atcttcatca gttgatgacc attttgacgt gtgacatgat
     9961 atttgtaaat atgcccttct tgagccatat tggtaaagac ttcccagacc ccaaaatcat
    10021 ttcttaccat tggaatctga ttttcaatcc agttggtaaa atcaccaacc aagtgaacag
    10081 cctgagcatt aggtgcccaa acacggaagg tatagccatg ctctccattt agttcttccc
    10141 tatgtgctcc tagataatgt tggagataaa aattttcacc cgtcataaag gtttttaatg
    10201 cttctctatt atccatatac tccccttctc ctgtaagcgt tttctatgtt tttattatac
    10261 taccttttta gagaagattc aagtaaatta ctatacttct ttaattattt tgaaaatcta
    10321 caacaagttc acttactcgt tcaattgtaa atcaatattt tttcaaaaaa ttgcgaaaac
    10381 gcctttcttt ttctactata gtgaaatgaa ataaaacatg cgcaagtcga ttaaggaatt
    10441 taatctaatt tctaacaatg tcttagaaat caaagtgtac tattttaact tcaatgt
//
LOCUS       DAVBOU010000066         9783 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVBOU010000066 DAVBOU010000000
VERSION     DAVBOU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9783
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.067"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ879_001920"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ879_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ879_001921"
     CDS             complement(546..1166)
                     /locus_tag="VQ879_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3144022.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ879_001922"
     CDS             complement(1166..1648)
                     /locus_tag="VQ879_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3144023.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ879_001923"
     CDS             complement(1648..2490)
                     /locus_tag="VQ879_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3144024.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ879_001924"
     CDS             complement(2585..3385)
                     /locus_tag="VQ879_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3144025.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ879_001925"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ879_001925"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3144026.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ879_001926"
     CDS             4918..5463
                     /locus_tag="VQ879_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3144027.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ879_001927"
     CDS             5475..5789
                     /locus_tag="VQ879_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3144028.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ879_001928"
     CDS             5806..6498
                     /locus_tag="VQ879_001928"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3144029.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ879_001929"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ879_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3144030.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ879_001930"
     CDS             7140..7730
                     /locus_tag="VQ879_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3144031.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ879_001931"
     CDS             7739..9502
                     /locus_tag="VQ879_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3144032.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         3031 a         1696 c         2081 g         2975 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ctgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg tggtataatc tttttatggc
     9721 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtataac
     9781 aga
//
LOCUS       DAVBOU010000067         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBOU010000067 DAVBOU010000000
VERSION     DAVBOU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.068"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ879_001932"
     CDS             complement(358..1965)
                     /locus_tag="VQ879_001932"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3144033.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ879_001933"
     CDS             complement(2355..2942)
                     /locus_tag="VQ879_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3144034.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ879_001934"
     CDS             complement(3070..3519)
                     /locus_tag="VQ879_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3144035.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ879_001935"
     CDS             complement(3524..3913)
                     /locus_tag="VQ879_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3144036.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ879_001936"
     CDS             complement(3941..4567)
                     /locus_tag="VQ879_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3144037.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ879_001937"
     CDS             complement(4581..5144)
                     /locus_tag="VQ879_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3144038.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ879_001938"
     CDS             complement(5597..6100)
                     /locus_tag="VQ879_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3144039.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ879_001939"
     CDS             complement(6293..7123)
                     /locus_tag="VQ879_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3144040.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ879_001940"
     CDS             complement(7108..8790)
                     /locus_tag="VQ879_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3144041.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2722 a         2058 c         1637 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBOU010000068         8739 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBOU010000068 DAVBOU010000000
VERSION     DAVBOU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8739
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.069"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ879_001941"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ879_001941"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3144042.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ879_001942"
     CDS             1085..2809
                     /locus_tag="VQ879_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3144043.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ879_001943"
     CDS             2811..4559
                     /locus_tag="VQ879_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3144044.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ879_001944"
     CDS             4816..6075
                     /locus_tag="VQ879_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3144045.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ879_001945"
     CDS             6325..6825
                     /locus_tag="VQ879_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3144046.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ879_001946"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ879_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3144047.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ879_001947"
     CDS             7456..7629
                     /locus_tag="VQ879_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144048.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ879_001948"
     CDS             7626..8222
                     /locus_tag="VQ879_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3144049.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ879_001949"
     CDS             8259..8396
                     /locus_tag="VQ879_001949"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144050.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..>8739
                     /locus_tag="VQ879_001950"
     CDS             8495..>8739
                     /locus_tag="VQ879_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3144051.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARESYKSIFQT
                     EGEIEYHDIKEVTDHDFRQFRGQVDIICGGFPCQAFSL"
BASE COUNT         2573 a         1674 c         1938 g         2554 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgatcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcact
//
LOCUS       DAVBOU010000069         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBOU010000069 DAVBOU010000000
VERSION     DAVBOU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.070"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ879_001951"
     CDS             complement(549..857)
                     /locus_tag="VQ879_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3144052.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ879_001952"
     CDS             complement(854..1162)
                     /locus_tag="VQ879_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3144053.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ879_001953"
     CDS             complement(1167..2462)
                     /locus_tag="VQ879_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3144054.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ879_001954"
     CDS             complement(2480..3889)
                     /locus_tag="VQ879_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3144055.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ879_001955"
     CDS             4047..4775
                     /locus_tag="VQ879_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3144056.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ879_001956"
     CDS             5234..5428
                     /locus_tag="VQ879_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3144057.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ879_001957"
     CDS             complement(5793..7103)
                     /locus_tag="VQ879_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3144058.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ879_001958"
     CDS             7340..8212
                     /locus_tag="VQ879_001958"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3144059.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2589 a         1457 c         1583 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBOU010000070         8016 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBOU010000070 DAVBOU010000000
VERSION     DAVBOU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8016
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.071"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ879_001959"
     CDS             226..6657
                     /locus_tag="VQ879_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3144060.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ879_001960"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ879_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7394..7579)
                     /locus_tag="VQ879_001961"
                     /pseudo
     CDS             complement(7394..7579)
                     /locus_tag="VQ879_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7607..7834
                     /locus_tag="VQ879_001962"
     CDS             7607..7834
                     /locus_tag="VQ879_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3144061.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7907..>8016
                     /locus_tag="VQ879_001963"
     CDS             7907..>8016
                     /locus_tag="VQ879_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3144062.1"
                     /translation="MVNCEPLEAYRQLAEAELVGCWAHVRRKFFEATPKQA"
BASE COUNT         3061 a         1116 c         1569 g         2270 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact ataaatccac gtttacgaat ctctttccac acttgttcaa
     7441 tggggttcat ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct
     7501 ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaga taatcatctg
     7561 gataagcttg tgaaagctcc tattcctaaa gcccctttat aacctcttgc gagagagact
     7621 attgactcag cccttacttc atgcggatga aacttcttat cgggttctag agagtcatag
     7681 ccatctgacc tactattgga cctttttgtc tgggaaagtt gagaatcaag caatcacgct
     7741 gtaccatcat gatcagagtc ggagtggttc ggtagtacaa gaattcctag gagattattc
     7801 tggctatgtt cattgtgata tgttgcggca gtaacttagg actttagtcc tctagttctg
     7861 cctatgcgat agcagtccaa ggtttaggag caaggcgacg ctaagcttgg taaactgcga
     7921 accgctagaa gcttatcgtc aactggcaga agctgaactt gttggatgtt gggcgcatgt
     7981 gagaaggaaa ttttttgaag cgacccccaa gcaagc
//
LOCUS       DAVBOU010000071         7494 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBOU010000071 DAVBOU010000000
VERSION     DAVBOU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7494
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.072"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            167..322
                     /locus_tag="VQ879_001964"
                     /pseudo
     CDS             167..322
                     /locus_tag="VQ879_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            522..3797
                     /gene="rexB"
                     /locus_tag="VQ879_001965"
     CDS             522..3797
                     /gene="rexB"
                     /locus_tag="VQ879_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3144063.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3794..7444
                     /gene="addA"
                     /locus_tag="VQ879_001966"
     CDS             3794..7444
                     /gene="addA"
                     /locus_tag="VQ879_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3144064.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2281 a         1576 c         1594 g         2043 t
ORIGIN      
        1 agattatacc acattgtgta ctatttttgg ttcattttac tatagtagat tgaaataaga
       61 tacgaacagc ttgattaggg aaatcaaatt aatttctaga aatattttag catccacggt
      121 gtactattat agtttcaatt tactatagtt caatcattct atcaagaata ttgaatatat
      181 aaaggcacgt aatattaaaa cttcttctga tatcgaatta gagtccgatg ttgatggcga
      241 taaatcagac aatctaccag tcgacattaa gatactggga caacacattg aagtgtattc
      301 cgtacctaag aaacaatcat aaaactcaaa gccttgttac cgaggctttt ttattatgtg
      361 attttcagta gccagactta ttctatctaa tacaagtaaa gctaagtatt taagatttag
      421 cagatgatga agaaaagaaa ggatggccta aatattttaa cagatttacg aggctaatca
      481 tggtataata tagggtgatg aaaaattcca acgaggctga gatgaaatta ctttatactg
      541 atattcggac ttctttgaca gaaattctaa caagagaggc agaagagcta gttgcagctg
      601 gcaagcgggt cttctacatt gcccccaact ctctttcttt tgaaaaggaa cgcgccgtgc
      661 tggaatgctt gtcccagcag gcttcttttt cgattaccgt cacgcgcttt gctcaaatgg
      721 ctcgttatct ggtcttgaat gatttaccag ctaaaactac tcttgatgat atcggtcttg
      781 ggttggcctt ttacaaatgc cttgccgaac tcgatcccaa ggacttgcgt gtttatggcg
      841 ctattaagca ggatcctcaa ttgatccagc agttaattga gctttaccat gagatgacca
      901 aatcccagat gagttttttg gacttggaga atttaacaga tgaggataag agggcggatt
      961 tactcttgat ttttgagaaa gtaacagcct atcttaatca aggtcagtta gcccagggaa
     1021 gtcagttgtc ccatttgatt gaggctattg agaatgacaa ggtaagtagt gattttaatc
     1081 aaatcacctt ggtcattgac ggctttactc gtttttctgc tgaggaagag cgggttgtgg
     1141 acttacttca cggcaaaggt gttgagattg ttatcggggc ttatgctagt aagaaagcct
     1201 ataccagtcc ttttagcgag ggcaatctct accaagccag cgtaaaattt ctccatcatc
     1261 tggcttctaa ataccaaacg cctgctcagg actgttctca aactcatgag aagatggata
     1321 gttttgacaa ggcctctcgt ttgttggagt cttcttatga cttttcagaa ctcgctttgg
     1381 atgtcgatga gaaagaccgt gaaaatttac aaatctggtc ttgtttgacg caaaaggagg
     1441 agttggagct agtagcccgt agtattcgtc agaaattaca tgagaactca gacctgagct
     1501 acaagcattt tcgtattctc ttgggggatg tagcttctta ccagttatct ctcaaaacca
     1561 tttttgacca gtatcagatt cctttttatc ttggtagaag cgaagccatg gctcatcatc
     1621 ccttgactca gtttgtcgag tctattttag ctttaaaacg ttaccgtttt cgtcaggagg
     1681 atttgattaa tcttcttaga actgatttgt atactgacct cagtcagtct gatattgatg
     1741 cttttgagca atatatccgc tatcttggta tcaatggctt gccagccttt cagcaaatct
     1801 tcaccaaatc ccaccatgga aaatttaatc ttgagcgttt gaatgtcctc cgcctgagaa
     1861 ttttagcacc tcttgaaacc ctctttgcca gccgaaaaca aaaggctgaa aacctcctac
     1921 aaaaatggag tgtctttcta aaagaaggag ctgtgaccaa gcagttacaa gatttgacaa
     1981 ccactttgga agctgtagaa caggaaagac aagccgaagt ttggaaggct ttctgccatg
     2041 ttttagaaca atttgcgact gtttttgctg gttcacaggt tagtctggaa gacttcctag
     2101 ccttgctcca ttctggaatg agtttgtccc aataccgtac cattccagca acagtggaca
     2161 ctgttctggt gcagagttac gatttgattg caccattgac tgctgacttt gtctatgcta
     2221 ttggactaac tcaggacaat ttaccaaaaa tttctcaaaa caccagtctt ctgacagatg
     2281 aagaaaggca aaacctaaac caagcgaccg aagaaggcgt tcaattactg attgccagca
     2341 gtgaaaatct caagaaaaat cgctacacta tgctttcctt ggtcaattct gctcgtaagc
     2401 agttgttctt gtcggctcca agccttttta acgaaagtga aagtaaggaa tctgcctatc
     2461 ttcaagagtt gatccatttt ggatttaggc ggagagagaa gaggatgaat cacaaaggac
     2521 tgtctaagga ggatatgggg tcctatcaca gtcttttgtc tagtctggtt gcctatcacc
     2581 agcagggtga gatgagcgat actgagcaag atttgacttt tgtcaaggtt ctgtcgcgtg
     2641 tcataggtaa aaaactagat ctgcaaggtc tggaaaatcc agctatccca accagtccaa
     2701 gcagcaagac cttagccaag gacaccttgc aagctctcta tcctgccaaa caggagtttt
     2761 acctgtctac gtcgggtttg acagagtttt atcgcaatga atacagttat ttcctacgct
     2821 acgttttagg cttgcaggag gaattacgtt tgcgtcctga tgcccgtagt cacgggaatt
     2881 tcttgcatcg tatctttgaa cgcgccttac agttgcctaa tgaagattcc tttgaccaac
     2941 gtctagaaca agctattcaa gaaaccagtc aagaacgcga atttgaagct atttatcaag
     3001 aaagtttgga agcccagttt accaaggaag ttttgcttga tgttgcacgg acgactggac
     3061 atattctccg acacaatcca gccatcgaaa ccatcaaaga agaagcaaat tttggtggaa
     3121 aagaccaagc ctttattcaa ttagacaatg gacgcagtgt ctttgtacga ggcaaggtgg
     3181 accggattga ccgtttgaaa gctaatggag cgataggagt agtagactac aaatccagtc
     3241 tgactcagtt ccagtttcct catttcttta atgggctcaa ttctcagtta ccaacctatc
     3301 ttgctgccct aaaaagagaa gggaagcaga actttttcgg cgccatgtac ttggaaatgg
     3361 ctgaacctgt ccaatctctg atggcggtaa aaagtctggc aggagcagtg gtagaagcca
     3421 gcaaatctat gaaataccaa gggctcttct tggaaaaaga aagcagttat ttaggcgaat
     3481 tttataacaa aaacaaggct aatcaactga cagatgagga atttcagctc ctactggact
     3541 acaatgccta tctttacaag aaagctgctg agaagatttt agcaggccgg ttcgccatca
     3601 atccttatac tgaaaatggc agaagcattg ccccatacgt ccagcaacat caggctatta
     3661 caggctttga agccaattac catctgggcc aagcccgttt cctagaaaaa ttggacctag
     3721 ctgatggcaa gcgtctggtc ggagaaaaac tcaagcaagc ttggtttgaa aaaataagag
     3781 aggagttaaa tcgatgaagc ttattccctt tttaagtgag gaggagattc aaaaactgca
     3841 agaagcagaa gcaaattcga gcaaggaaca gaagaaaact gccgaacaaa tcgaagctat
     3901 ctacacttct ggtcagaata tcctggtctc agcatcggct ggttctggaa agacctttgt
     3961 catggcagag cgcattctgg accaattggc gcgtggtgtc gaaatttctc aactctttat
     4021 ctcaaccttt accgtcaagg ctgcaactga acttaaagaa cgtttagaga aaaaaatcag
     4081 caagaaaatc caagaaacag atgatgtcga tctcaaacaa cacttgggtc gccagttggc
     4141 agacctaccc aacgctgcca tcggaaccat ggactctttc acacaaaaat tccttggcaa
     4201 acatggttat ctgcttgata ttgcacctaa tttccgtatt ttacaaaacc aaagcgagca
     4261 acttcttctc gaaaacgaag tctttcatga ggtctttgaa gcgcattacc aaggtaaaca
     4321 gaaagagagc tttagtcatt tgctgaaaaa ctttgctggg cgtggcaagg acgaacgggg
     4381 tctgcggcag caagtctata aaatctatga cttcctccaa tccaccagta atcctcaaaa
     4441 gtggctgagt gaatctttcc tcaaaggctt tgagaaagct gattttacca gtgaaaaaga
     4501 aaaactgact gagcaaatca aacaagccct ctgggatttg gaaagatttt tccgttacca
     4561 tctggataac gatgccaagg agtttgcaaa ggctgcctat ttagaaaatg ttcagttaat
     4621 tctggatgaa attggctccc taaatcagga gttcgatagt caggcttatc aggcagtact
     4681 tgcgcgtgtt gtcgccatct ctaaggagaa aaacggtcgt gctctgacta atgccagccg
     4741 taaggctgat ttgaagcccc tggctgatgc ctacaacgaa gagagaaaga cccagtttac
     4801 taaactagga caattatcag accagatagc gattctcgac tatcaagaac gttatcatgg
     4861 agacacttgg aaactagcta aaaccttcca atctttcatg agcgattttg tagaggctta
     4921 tcgtcagaga aaacgacagg aaaatgcctt tgaattcgct gatatcagcc attacaccat
     4981 tgagatttta gaaaatttcc cacaagttcg tgagtcttat caggagcgct tccatgaagt
     5041 catggtcgat gagtatcagg ataccaacca tattcaagaa cggatgctgg aattgttgtc
     5101 taatggccac aatcgcttta tggtgggaga tatcaagcaa tccatctatc gtttccgtca
     5161 ggcagacccg cagattttca atgagaaatt ccaacgctat gcgcaaaatc cccaagaagg
     5221 caagctcatt ctcctcaagg aaaatttccg tagtagttca gaagtgctgt cagcaaccaa
     5281 tgatgtcttt gaacgtctca tggaccaaga ggtcggcgaa atcaactatg ataacaagca
     5341 ccagcttgtt tttgccaata ccaaactgac tcccaatcca gacaacaagg cagaatttct
     5401 cctctacgac aaggacgata caggtgagga agaagagagt caaacagaaa cgaaactaac
     5461 aggcgaaatg cgcttagtta tcaaggagat tctgaaactt catcaagaaa aaggtgttgc
     5521 ctttaaggaa attgcccttc tgacctccag ccgcagtcgt aatgaccaga ttctcctcgc
     5581 cctgtctgag tacgggattc ctgtcaaaac tgacggagag caaaacaatt atctccaatc
     5641 cctagaagtg caagtcatgc tagacactct tcgtgtcatt cacaatcccc tgcaagacta
     5701 tgccttggtt gcccttatga agtctccaat gtttggtttt gatgaggatg agctagcacg
     5761 tttgtccctt cagaaagcag aggataaagt ccacgaaaat ctctatgaga aactggtcaa
     5821 tgcacaaaaa atggcaagta gtcaaaaagg cttgattcac acagctctag ctgaaaaact
     5881 aaagcaattc atggatatcc tagcttcttg gcgcttgtat gccaaaaccc actctctcta
     5941 tgacttgatt tggaagattt acaacgaccg tttttattat gactatgttg gggctttgcc
     6001 gaatggtcct gctaggcagg ccaatctcta tgccctagca ctgcgtgctg atcaatttga
     6061 aaagagcaat ttcaaaggtt tgtcgcgttt tattcgtatg attgaccaag tcttagaagc
     6121 ccagcacgat ttgtcaagcg tggccgtcgc accgccaaaa gatgcagtag agctcatgac
     6181 catccacaag agtaaagggc tggagtttcc ttacgtcttt atcctcaata tggatcaaga
     6241 tttcaacaag caagactcta tgtcagaagt cattctcagt cgtcagaatg gtcttggtgt
     6301 caaatatatt gccaagatgg agacaggggc agtagaagac cactatccta aaaccatcaa
     6361 actctccatt cctagtctga cctataggca gaacgaagag gaattacagc tagcaagcta
     6421 ttctgagcag atgcgtttgc tgtatgttgc tatgacgcgg gctgagaaaa agctctatct
     6481 tgtcggcaag ggttctcgtg aaaagctgga agtcaagcaa tacccagcag ccaaaaatgg
     6541 gaaactaaat agcaatacta gactgcaagc acggaatttc caagattggc tttgggctat
     6601 cagtaaagtg tttactaagg acaagctcaa ctttagttat cgttttattg gcgaagatca
     6661 gttgaccaga gaagctatcg gagagttgga aaccaagagt cctctccaag atagctccca
     6721 agcagacaat cgtcagtcag ataccatcaa agaagctctg gaaatgctga aggaggtgga
     6781 agtttataat actcttcacc gcgcagctat tgaacttcct agtgttcaaa ccccaagtca
     6841 aatcaagaaa ttctacgaac cagttatgga tatggaaggt gtcgagattg ctggtcaagg
     6901 tcagtcagta ggcaagaaaa tcagcttcga tttgccagat ttttcaacca aagaaaaggt
     6961 aactggagct gagattggta gtgctactca cgaactcatg cagagaattg acctcagcca
     7021 gcaactaacc cttgctagcc taacagaaac actcaaacaa gttcaaacta gccaagctgt
     7081 cagagacaag atcaatcttg ataaaattct tgctttcttt gacacagtac tcggtcagga
     7141 aattcttgct aataccgacc atctctatcg cgagcaacct ttctccatgc tcaaacgaga
     7201 ccaaaagagt caggaagact ttgttgtccg tggtatcctt gatggctatc tgctttacga
     7261 aaacaaaatt gttctgttcg actacaagac agaccgctat gatgaaccaa gtcaactcgt
     7321 agaccgctat cgtggtcagt tagctctata cgaagaggct ttatcacgag cctattcgat
     7381 tgaaaatatt gaaaaatact tgattttact cggtaaagac gaggttcaag ttgtaaaagt
     7441 ataacttata ctctttgaaa atctcttcaa accacgtcag cttcgccttg ctgt
//
LOCUS       DAVBOU010000072         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBOU010000072 DAVBOU010000000
VERSION     DAVBOU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.073"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            52..693
                     /locus_tag="VQ879_001967"
     CDS             52..693
                     /locus_tag="VQ879_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3144065.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VQ879_001968"
     CDS             complement(735..2723)
                     /locus_tag="VQ879_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3144066.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VQ879_001969"
     CDS             complement(2725..3483)
                     /locus_tag="VQ879_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3144067.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VQ879_001970"
     CDS             3911..4102
                     /locus_tag="VQ879_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144068.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VQ879_001971"
     CDS             complement(4456..4728)
                     /locus_tag="VQ879_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3144069.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4787..5236)
                     /locus_tag="VQ879_001972"
     CDS             complement(4787..5236)
                     /locus_tag="VQ879_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3144070.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(5223..7352)
                     /locus_tag="VQ879_001973"
     CDS             complement(5223..7352)
                     /locus_tag="VQ879_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3144071.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2210 a         1562 c         1472 g         2230 t
ORIGIN      
        1 tcagaaacaa atcacgaaat cgattcaaat tttgcaggtc gtttaaatat cctgcgcgca
       61 ggtgttcttg gtgctaacga tggaattatt tccattgctg gtgtggttat cggggttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggat ttgcggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgtta gaccaagata gggaactagc caaaaaatcc
      301 ctcgatgctg cttatatcca aaatggagaa tgcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctact
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca ctagtgccag acttggaaag
      601 gatccgacta gaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaacca actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttcacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgata
     1861 gttgctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttattaggtt ggtaatagta tttcttattt ttctttaaga tttgaaggaa aacggtaatc
     1981 cctgcattga acaaaagata agtaccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatatccaat ccctaaactt
     2101 atggaaccaa gaatagtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaagaagt actgtaatga caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttga tacccagatt ttcagctgtc atcaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcag cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa
     4141 aatgaaataa gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt
     4201 agaagtagag gtgtactatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac
     4321 taaattacag cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagatttttg cttattccaa
     4441 atcttctgta gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat
     4561 agaagctagg atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatggc
     4621 aaacaagaaa cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac
     4681 tcctgaaatc atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct
     4741 ttctgctagg ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct
     4801 gatttatcag aagcaattta cctcgacaaa gtccacagcg atagcgttgg gtatcaatcc
     4861 tacgcttgcg ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag
     4921 agttactatt gggcaaggat ggtacaaacc ttaatccatc cactgctttc aaaagttcct
     4981 taaaatcccg atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga
     5041 gttcatgtcg gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat
     5101 taaaatccag atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat
     5161 tccactggac atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat
     5221 aatcagtcag tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca
     5281 attttcttga cccaaacggt caccaaatct ccaactgaca ccacttgact agggtgtttg
     5341 ataaacttgc gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca
     5401 acgaaggcac cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact
     5461 aggtctttga tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa
     5521 tctcgacctg gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct
     5581 agctcttgag ccatttcctt gactgaaagg gacttgagtt tgctttgggc ttcttcgttt
     5641 aggtctttaa tatctaaacg tttgaagagt tccttaactg cagtgtaatt ctctgggtga
     5701 actcctgtat tatcaaggat attgctactt tcagggatac gaaggaaacc agcagcctgc
     5761 tcaaaggcct tggctcccag acgaggaact ttcttgattt gggcgcgtga agtgattttt
     5821 ccttcttcct cgcggtattt gacaatattt tcagagatag ttttgttgag tccagctacg
     5881 tgtgaaagaa gagctgggct agctgtattg acattgacac caacttggtt aaccactgta
     5941 tcgacaacaa agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga
     6001 ccgacaccaa ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga
     6061 cgggcgatag aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca
     6121 agttcgctgg cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca
     6181 gggaaatctt tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt
     6241 ccaatggcaa taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct
     6301 tcttcgattt gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt
     6361 tttcctgttg catccacgac agctaacttg gcacctgtac gaaaggctgg gtcaaatcca
     6421 agaaccacgc gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa
     6481 agttggatag ctccttcttc agctttctca gttaattctg tccgaatacg acgctcgata
     6541 gcaggcaaga cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc
     6601 accttgaaac gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc
     6661 ttcaagacac caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt
     6721 ccaactgtct ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca
     6781 tccttggctt gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc
     6841 aaggtcacat cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc
     6901 ttgccagtcg caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata
     6961 ttctgcaaaa tcaagcgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg
     7021 gtacgacgct tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca
     7081 actaagatag cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag
     7141 acagcttcct tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta
     7201 atcgccacct catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata
     7261 gtcgcccctt cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa
     7321 tcctgagaga ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc
     7381 tttctccaat ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta
     7441 ggctgctcaa aatactgttt tgaggttgtg gata
//
LOCUS       DAVBOU010000073         7451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBOU010000073 DAVBOU010000000
VERSION     DAVBOU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.074"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(173..1588)
                     /locus_tag="VQ879_001974"
     CDS             complement(173..1588)
                     /locus_tag="VQ879_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3144072.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VQ879_001975"
     CDS             complement(1601..3439)
                     /locus_tag="VQ879_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3144073.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /locus_tag="VQ879_001976"
     CDS             complement(3457..4296)
                     /locus_tag="VQ879_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3144074.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7276)
                     /locus_tag="VQ879_001977"
                     /pseudo
     CDS             complement(4597..7276)
                     /locus_tag="VQ879_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2443 a         1568 c         1026 g         2414 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc cagtttttct
     4201 tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatat aacaagcctc ttggcagcca taaataataa tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcttct tggattaaca gtgccacttt agcagttgaa accctctgaa tttcttgtag
     6481 atacctccat tggtcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atggtaagct tctccttgaa aaggcaaggc aatcaaattt ccaaatcccc cccttaggaa
     6601 ggacatcctg atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct
     6661 gcattgccag ttctatcagt ttctttccaa acaagcgagc ctctcgactc ggaatcgctt
     6721 cctcaaagaa gaaccaaata tggagtccgt gacccgaacg agaaatctct aaatgggctt
     6781 ccatctggcg ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt
     6841 catcaaaatc cagtaccaaa aaatgacagc tatcatctaa gtgcatagga aagataccga
     6901 tagctgtctc cccacgaaaa tgagatttca aaacggagtc cgtcaatgtc tggaaactcc
     6961 gtttttcaag tggcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc
     7021 cttgatcatt gataaaactc ttagcataaa catcataacg gccagcaaac acggaggtaa
     7081 acaattgtaa tttttcttgc gtcgtcaagt gactactttg aagttggaac atctcctcga
     7141 accgagagcg ttccatcaca aactgactct tgtctttaag acgtttacac aagaaaaact
     7201 cactatcccc attaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag
     7261 acacaaaaat agccataaca atcacctcct tgattcctat aggctgatta taacaagaat
     7321 ggctgaaatt gtacacgaaa ataaaatccg aatagcactc attttgtatg cgactaatag
     7381 tccatctcgc tccggaatgt acgaagtaaa tagagtttaa acgagcagtc tataaaattc
     7441 aaaaaacgca t
//
LOCUS       DAVBOU010000074         7014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBOU010000074 DAVBOU010000000
VERSION     DAVBOU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.075"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(213..1094)
                     /locus_tag="VQ879_001978"
     CDS             complement(213..1094)
                     /locus_tag="VQ879_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3144075.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(1235..2563)
                     /gene="vncS"
                     /locus_tag="VQ879_001979"
     CDS             complement(1235..2563)
                     /gene="vncS"
                     /locus_tag="VQ879_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3144076.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(2560..3216)
                     /gene="vncR"
                     /locus_tag="VQ879_001980"
     CDS             complement(2560..3216)
                     /gene="vncR"
                     /locus_tag="VQ879_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3144077.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(3265..3348)
                     /gene="pep27"
                     /locus_tag="VQ879_001981"
     CDS             complement(3265..3348)
                     /gene="pep27"
                     /locus_tag="VQ879_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3144078.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(3529..4908)
                     /gene="vex3"
                     /locus_tag="VQ879_001982"
     CDS             complement(3529..4908)
                     /gene="vex3"
                     /locus_tag="VQ879_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3144079.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(4960..5607)
                     /gene="vex2"
                     /locus_tag="VQ879_001983"
     CDS             complement(4960..5607)
                     /gene="vex2"
                     /locus_tag="VQ879_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3144080.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(5620..6897)
                     /locus_tag="VQ879_001984"
     CDS             complement(5620..6897)
                     /locus_tag="VQ879_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3144081.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         1962 a         1530 c         1370 g         2152 t
ORIGIN      
        1 agtggagtga aataggatac gaacaaattg attaggaaaa tcaaatgaat ttatagaaat
       61 cttttagcag ttatgttgtc ctattctagt ttcgaaacgc tatagaagca gcattgtgct
      121 agtctagatt cagtttacta tactaaaacg agtagcttgg aatcaaaaaa cccaccctca
      181 caggcaggtt ttatctgtat tattcagcta gattatgctt taccttctga accgaatacg
      241 tcgatacgtt cttcaaccga tgcttggata gcttttacac cgtcagccaa gaatttacgt
      301 gggtcgaaga gttttttctt gtcgtattct gcttcgtttg cttcgtagtc acgagcaaat
      361 ttacgagttg cgttagcgaa tgcgatttgg cattctgtgt taacgttaac tttggcaaca
      421 ccaagtttga tagctgcttg gatttgctca tcaggaatac ctgatccacc gtgcaatacg
      481 attgggaatc ctggaagagc ttctgtcaat ttttgcaagt ggtcaaggtc aagaccttcc
      541 cagtttactg ggtaagggcc gtggatgtta ccgataccag ctgccaagaa gtcgatacca
      601 gtttcaacca ttgctttagc gtcttcgatt ggagccaatt cacctttacc gatgattccg
      661 tcttcttcac caccgatagt accaacttca gcttctactg agataccttt agcgtgtgct
      721 ttttcaacaa cttctttagc caatttaagg ttttcttcaa ctggaaggtg tgaaccgtca
      781 aacatgattg aagtataacc aacttcgata cactcaagtg catcttcgta gtgaccgtgg
      841 tcaaggtgga tagctactgg tacagtgata cccattgatt caacaaggtt agcgatcaag
      901 ttgcgagcaa ctttgtaacc acccatgtat ttagcagcac ccattgaagt ttggatcaaa
      961 actggagctt ttttagcttc tgctgcgcgc aagatagctt gagtccactc aaggttgttt
     1021 gtgttaaatc caccaactgc ataaccgttg tcacgggctg cttggacaaa tttttctgct
     1081 gaaacgattg ccattttatc aggcctcctg tatattttta tgggtcatcc catttacatt
     1141 gttcatttta tcactttttg ccaaaaaaat ctagtttttc ccgcagtttc gattgatttt
     1201 cttctaactc catctatgta aaccctttct ctccctagtc ttggacgact tttggaaaat
     1261 ctataaagaa ggttaaacga ttctcctcca tctcgaaacg ataagctaat ttttcatgtt
     1321 ctaatagact cttaaccaca aagagcccca taccagaccc cttgaccttg cgactggcat
     1381 tgtcagaaaa agactgggct agtttttctt gttcctctga gctacagcta ttttcgataa
     1441 aaagttctcc ttctctttct ccaattcgaa ctaagccacc tggaacagag tgcttaatgg
     1501 cattgctgat gagattagaa agaatcaact tcataactga tgggtttaga taagcctgct
     1561 gatgggtcaa actattgtct atctggagct ctctttcctt ggctagcaag gcataatctt
     1621 tgaccagatt ttgcgtcatc tggaggaggt caattgtttc cctatcatct cgcaattcct
     1681 gcacagaaga gagggaaagt atctgcagaa catggtgatt gagttcatcc acaatcccca
     1741 aggcaactcc cagatactgg tctctattct tataacgacc gatattctct ctcatatttt
     1801 cgattaggat tttcaaacta gccagcggtg ttttcaattc atgagaagct cctcgtagga
     1861 attcgacctt catcttctcc agctggagaa tggcttcatt cttttcatgc aagtccgcaa
     1921 taacagtcaa gagatgctgg tagaggctat tgatttgttc cttgagattg cctatctcat
     1981 ccttagaatc cacgcgcaat cgcacttggg aatccaggtc catcatccga cgggtcaccc
     2041 gcttgatttc caaaatcggt gcaacaatag tccgagcgta gatgtaggcc accaagaggg
     2101 aaatcagaaa ggaggccagc aaggtatagg gaagaaactg gagactgatt tgctccgctt
     2161 ccttttgtaa atccatggaa gctagaaact ggagaatcat agtaccaccg tcttgcgttt
     2221 tcacctcgcg ctcctcaata aagagagagg ttgtctggcg gtctgtgtcc agaggaagac
     2281 tgtccttgac ttctaacttg tcctcggtca tctcaccttt gacggtcccc ttgatatcac
     2341 tagtctggga atacaagtct aacacttgct cgatactctg cctatctttc ccttctaggg
     2401 actgggcaat ggctgttgcc ttttgaccaa tggtttcctg acgatgactc agataagtcg
     2461 aaggaaaaag aaaataaata gctaaatgaa ggcagataac cagaacacta aatatcgaga
     2521 aggtatagat aaatatcttt gtaaataaac ctgttcgttt cattttcgct ccaatttata
     2581 accaacattg cgcacagtga ggatacaatc caagtctagc tttttccgca attccttgat
     2641 ataaacatca ataacacggt caaagggaac ctcatctgtc gctttccaga cggcatcgat
     2701 aatctgagac cgagtcaagg cccggccttc atttttcact agatagtcca gaatttccaa
     2761 ctctttggca ttgataggca cttcttgacc tgcgaggctt gcactgtagc tttcaaagtc
     2821 caccttggta tccttgtaag aaaagattcg tcctgtatcg tagtagcgct tgaaaatcgc
     2881 gtccaccctc acttttaaga gggagaggga gaaaggtttt tccagatagc catctgccaa
     2941 agaggcaaag gcactcatct tgtattcctc atcctgaaaa gctgtcaaca tcaagacagg
     3001 aacctgactg gttttacgaa tctcagctag gacttctaag ccgttaagct tgggcatctg
     3061 gatatccagt aaaaccaggg ccacctcata gctagaaaat tgctccagag cttcctgacc
     3121 gtccgctgcc tcaatagttt catagccaca atccgtcaaa taatcactga ccccctcacg
     3181 gatcatctct tcatcttcta caattaaaat tttcatactt taactgctct ctatttttta
     3241 tttttcttag aataaatacc tactctattt tctattatag tctcttgctg gccttttgtc
     3301 tgtaagcaac tgaccactag ataaaacgtt gtgaaattcc tttctcataa attccataac
     3361 tttagtatat tatatttaag cactaaagta caaagaaagc aactgaaagc aatgattttc
     3421 accactgctt tcagatttat tttgaattgt taaatagcta ttcctatcca ctattcttga
     3481 atagaaacac aagatgcaat ctttattcca gactcatttt tttcaaattt attcaccatc
     3541 cagcaagagc tcttttggtt gttttctaag gagattgctt gaagcaagcg ccataacgag
     3601 aaccactaga accaaggcaa ggacaaaaat gatgataaag tctgatgtct gaatggaaat
     3661 gtctaggctc gacaaggtct tgctaaagcc atctacttct gcaccgccac caaggttaga
     3721 ggcttgagcc gccttactag cctgtttggc aacacctgaa gtcacattgg caaggacagt
     3781 gtttccaatt gcacgggcag tgtaattagc taggaagtaa gcagaaacta gagcagggat
     3841 agcaatcaag atagattcgg tgatgaattg acccaagata cttgcctgct tgagaccaat
     3901 agagaggagg attcccactt ccttgcgacg ggcattgatc caaagactga gcaagagggc
     3961 aaggagaagg actgagaagc tcaagctacc ccagaagagg aggttggcca tcttgtacat
     4021 accagagata gattgctcaa gagctgggta gttagaggag ctcttgacga gtgtgtagct
     4081 cttccagttg ataccactga tgccattcaa ctctttcata acatcatcca agttcttgtc
     4141 tgctgttaca aagaaggttg cgtccccata aatggctgtg tcttctgtgt atccataaag
     4201 ttttgcagca gtgtgaatgt ctgtaatagc tgtgttttcg taaagttctt gtgagtaggt
     4261 tactgctgac ttattatgac catcaaagag tcccttgatt gtcacttcaa ctgtttcctt
     4321 ggctcctttt tcattatctg catcgtagat attagagtcc agtttaacct tgtcccctac
     4381 tttccagccg tgtttggctg ccaagtcctt gtgcaagagg attttatcct tgtcgtcgtt
     4441 ggttaagtgc tctccttcga ctagtttata agaaccagag acaaacttat cttctttaga
     4501 ggagtcattg acacctgtaa tcatcaagct acttccaaaa cgtttggcac gatcagcagt
     4561 gagattcttc ttggtttctg gcgtttcaat caggtcatat ccagtcaaat ctccgatagc
     4621 gttgatacgt ttgacataag actcaatggc cttgttttcg gtgatttttt tgatgtcttc
     4681 acccttgata ttcccagcac cacgaggcgt tccttggttg acgcgacgat tgatttgcat
     4741 ggagaagcta ttggtgatat ttttaaaggt ctcctgagaa gccttggcag tagctccctt
     4801 gattgacaag ccgaccaaac tcaagctcgc cataaggaga ataatcagga agatgacaat
     4861 cgatttgaaa aacttccttg taacataggc aaatgcgttg tgtaacatag attccctttc
     4921 tagattttgt tttaatcatt ctatcaaaat aagctcaaat tatttactag tattgcgcgt
     4981 ttcagtcagt ttcttatcct ttaattcaag tgtaatatct gacgcttgtg ccacttcttt
     5041 actgtgagtt acgacaatca cacatttacc tgttttctgg gcaagtgatt tgagtagttc
     5101 gacaatatct ccagcagttt taggatccag atttcctgtt ggctcatcag ctagaataac
     5161 tggagcttct gagaccaaac tgcgagcaat ggcaacacgt tgctgttgac cacctgataa
     5221 ctggagaaca ttccgcttaa tctggctttc atccaaacca agctcaagaa gtgtattctt
     5281 gcttgccttt ttgttgacca attggatatt ttccagcgga gaaagataat ctatcaagtt
     5341 ataattttga aagaccaggg aaatatggtg catgcgatgg taagaatagc ccttcttacg
     5401 aatatcctct ccttgaaaaa ggatagaacc ttcaacagga ctatctagac cagcaagtag
     5461 ggacaagagt gtggattttc ctgctcctga ctccccaata atactgtaaa attttccggg
     5521 ttcaaaatta taattgatct gatataggac tgcttcagca gtattcttat aacggtaggt
     5581 aacatcttgt aattgtaata aagtcatgat ttctccttct taactaatag atgataaaat
     5641 ttctttcggt gattttctaa ataagaatag gaaacaaagg gctacagata agcaactaag
     5701 cagaactaga aaaacatagg attctgcaaa agataagatg ctagttgata aactgcttgc
     5761 tttggctagt gtatcttgta agcttacctg atctccactt gctagtagag tttggagtag
     5821 gtaagttgtg attccgtttc ctgcaacaaa tgctggaagc aaagctccaa gagataccaa
     5881 aactacctct aaacagaatt gtaggaagat cgagctcttg ccttttccaa gtgcaagtaa
     5941 aatccccact tcatagaccc gttctctcaa ccagagagac aaaaccagaa ttaaggctcc
     6001 agctcctgct atcaacatcc cataaaggaa gatggtcagg aaggtttgga aagttgcaac
     6061 tgagtctttg atttgttcaa aagccttgtt ttccttttcg acttggtagc cttgattttc
     6121 caaggccaag ttttctacct gcttcatgag tccgtccatt tccttaggat tttctacata
     6181 gaagcgtgct gcactgactt gagcttcact attgcccaaa agggtttggc tactttcata
     6241 atctgtaaag acttgatttt cactgaagtc agaagacaag cctgtgaatt tctcttgttt
     6301 tttaccagaa aagatgccga taatctcaaa ctctactgtt tgtccttttc cagattcaga
     6361 ctgaccagca tccaagccaa tcttgtcatg aagtgaaaga ccgttcttct tagccaattc
     6421 ttcgtggata aggattttct tggaatcccc tttttgaagg tgtcgccctt cttttagatt
     6481 gaaagccgaa ctggtaaagg ttacatcctt ggatgaatcc tcaagagccg ttaagctaac
     6541 caagttattg tctgcagctg ataaatcatc acgctccacg ctctgctcgc cagtcactgc
     6601 ttccttgtct tttagttttg cgaccgtctc aagttcagga gagacatttt ccagcccctt
     6661 aatcttgctt acagatgcta ggtctgacaa cttgaatgtc tgaccattct ctatcttctt
     6721 aatagaaaaa gatgtattga gtgatttata aagattgctt tctactgttt tgttggactt
     6781 catcagagtc aaacaggctg aaattccggc caataagacc aataaaatca gaaataaaat
     6841 aaaacttctc agtcgctttc tgctgacata agcccaagat ctttggattg gattcatttg
     6901 tcacctccat atttgtaaga ctattataaa acccaaatat gaaatgttta tgaaatacga
     6961 aaaaaaatat cgagtagggg ataatctcta gcccctctca caccaccgta cgtg
//
LOCUS       DAVBOU010000075         6943 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBOU010000075 DAVBOU010000000
VERSION     DAVBOU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6943
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.076"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ879_001985"
     CDS             complement(57..287)
                     /locus_tag="VQ879_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144082.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ879_001986"
     CDS             complement(305..946)
                     /locus_tag="VQ879_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3144083.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ879_001987"
     CDS             complement(958..1692)
                     /locus_tag="VQ879_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3144084.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ879_001988"
     CDS             complement(1695..1892)
                     /locus_tag="VQ879_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144085.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ879_001989"
     CDS             complement(1892..2098)
                     /locus_tag="VQ879_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3144086.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ879_001990"
     CDS             complement(2108..2422)
                     /locus_tag="VQ879_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144087.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ879_001991"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ879_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ879_001992"
     CDS             complement(2718..4007)
                     /locus_tag="VQ879_001992"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3144088.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ879_001993"
     CDS             complement(4104..5333)
                     /locus_tag="VQ879_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3144089.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ879_001994"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ879_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3144090.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ879_001995"
     CDS             6501..6842
                     /locus_tag="VQ879_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3144091.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2249 a         1442 c         1278 g         1974 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccaccg aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggactgct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt caccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagccgc agg
//
LOCUS       DAVBOU010000076         6854 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBOU010000076 DAVBOU010000000
VERSION     DAVBOU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.077"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..654
                     /locus_tag="VQ879_001996"
                     /pseudo
     CDS             1..654
                     /locus_tag="VQ879_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(718..1800)
                     /locus_tag="VQ879_001997"
     CDS             complement(718..1800)
                     /locus_tag="VQ879_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3144092.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1797..2773)
                     /locus_tag="VQ879_001998"
                     /pseudo
     CDS             complement(1797..2773)
                     /locus_tag="VQ879_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
     gene            2988..3365
                     /locus_tag="VQ879_001999"
     CDS             2988..3365
                     /locus_tag="VQ879_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3144093.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            3600..4991
                     /locus_tag="VQ879_002000"
     CDS             3600..4991
                     /locus_tag="VQ879_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3144094.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5105..5947
                     /locus_tag="VQ879_002001"
     CDS             5105..5947
                     /locus_tag="VQ879_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3144095.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            6220..6504
                     /locus_tag="VQ879_002002"
     CDS             6220..6504
                     /locus_tag="VQ879_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3144096.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            6471..6797
                     /locus_tag="VQ879_002003"
     CDS             6471..6797
                     /locus_tag="VQ879_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3144097.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
BASE COUNT         2133 a         1161 c         1503 g         2057 t
ORIGIN      
        1 catggttggc gaaatattac gccacgtcca gaacatccta agaaagcaga cgctcaaacc
       61 attgtcgcgt ctaaaaataa aatctcaatt caagaagaca agaaagcgct ttaaaaccag
      121 tagacctttt cataaggttc gcttgatgta ccaagatgag gctggtttcg gtagaatcag
      181 taaactggga tcttgttggt ctccaatagg agtaggtcca catgtccata gtcactatat
      241 acgagaattt cgctattgtt atggagctgt tgatgcccat acaggcgaat catttttctt
      301 aatagctggt ggatgtaata ctgagtggat gaacgccttt ttagaagagc tttcacaagc
      361 ttatccagat gattattttt tactcgttat ggacaatgct atatggcata aatcaagtac
      421 cttaaagatt ccgactaata ttgattttac ctttattcct ccatacacac cagagatgaa
      481 cccattgaac aagtgtggaa agagattcgt aaacgtggat ttaagaataa agcctttcga
      541 actttggaag atgtcatgaa tcaactccaa gatgtcatac aaggactgga gaaggaggtg
      601 ataaagtcca tcgttaatcg gagatggaat agaatgcttt ttgaaagcag atgagtataa
      661 aattgaattg cttataaaaa agctccatac actggatgtg tatagagcaa tggggcttta
      721 tttgatatag agttcttggt tttttaggac aatttctcgg atacttgcaa actttttaag
      781 ttttttgatt tcttctggat gagtgacgag agtaataaca tatccttcct tgcctatacg
      841 gccagtacga ccagcacggt gtgtgtaggt ttcgctatct ctaggaatat caaagtttac
      901 gacacattct aggctatcga tatcaattcc acgagccaaa aggtcagttg caagaagcag
      961 ggttagttgg ttatctttaa acttttctaa gatgattttt ctaaatttaa cattaacatc
     1021 actagcgagg gaaacagtca atatatcacg atactgtagt ttttcctcgg cattcccaag
     1081 gtctgacagg ctattgaaga agactagacc acggaaatcc tctacatgag ccagttttcg
     1141 tagcatatcc actcgatgac gttggtctac ctgcatgtag aaatgctgga tattgtccaa
     1201 tttttggtca gagagatcaa tagtgcgtgt attcggcaca atcttttctt ggtcaaactt
     1261 ggtcgtggca ctcatgtaga ccagttggtg gtcacgaggt gcgtagtgag tgattttttc
     1321 tacaaagtga atctgagaat catctagtaa ttggtcaaat tcatccagga tgatggtttc
     1381 cacattcatc atcttgattt ttttaagttt aatgagttca aagatacggc caggagttcc
     1441 aatcagaatt tctggcccct ttttaagacg ttcaatttgt cgtttctgac ttgaacctga
     1501 aaggaagagt tgagcagtca atccgatagc ttctgcccac gttttacata catcaaaaat
     1561 ctgtccagca agttccgtgt ttggtgctag aatcaagagt tgttgggctt ttttcttttg
     1621 tagtctgaga agacttggta ggagatacgc tagggtctta ccagttccgg tttggctcac
     1681 tcctaggagg ttttctccag caagaagggg ctcaaatagt tgagtttgaa tgggggtgaa
     1741 ttcttggaaa ccgagttggt cactcagttc ttgccattca gtcggtagtt tggttttcat
     1801 ttttctgcct caaatctaat gccagcagtc tggcgcatgg tatatagtag ctcatgaaca
     1861 gagcctgcat catacagcca agttttgtag agattcagat ctggttgctg gatcatgtgt
     1921 gcaaatgcag cgacttcctc agtcatcgta tgaggagcct gttggatagg aagctggact
     1981 tgatttcctt ggtggtcggt aaaaatagct gagcgaatat gctcaatcgt gttgagagtc
     2041 aaggttccat ctgttgtata aatctcgcaa ggaagattgg aagtgatgtt ttttccagcc
     2101 ttgatgtgaa cttgatagtc tgggtagaag aggataccat ctccatttag gtcaatgcta
     2161 ttgtcaagct gttgagcatg gtaagtcgcg tcattagctt tttcaaaaag acgaacagca
     2221 gcatagaggg gataaatccc caaatccatg agggctccac cagcaaaacg gtctgaaaag
     2281 acatttggtg tttgtccagc caacaagtca ggcatcttgg aagagtattt ggcatagttg
     2341 aaatctgctc ctaacacttg cttatctgtt aaaaagtttt tgatagtagt aaaggctttc
     2401 tcgtggtaat tacgagctgc ttcaaagata aaacagttat ttttgaagct gtttgaatca
     2461 aatcaaacca ttcttgtggt tgagtgacag ctggcttttc gagaataaca tgtttaccag
     2521 cagacaaggc agcttttgcc tgagcaaaat gtaaggagtt tggactggcg atatagacta
     2581 aatcaaaaga agatttgaag aagacttcta attgatcgaa tagttggata ttctgatagc
     2641 gagaagcaaa ggttgctgca gtttctagtt ttctagaata gattgcgacc agttggtatt
     2701 ctccactggt atgggctgct tctatgaaat gatggctgat agcgccagtt ccgatgacac
     2761 ctaattttag cataaatact ccttttccga ttttaaatcc ttctttcatt ataacataga
     2821 tagacgggac tatccaacag agaggagaaa atttcaaata agctattagc tttcttttcc
     2881 gaataaatag atagaagcat agaatctagc aaacctagat ttaaaaatgt gctataatag
     2941 aaggaggaaa aggaggattc tcagacatcc aggtatcagc ccaactaatg atttgtcaat
     3001 ttatccgcga tatgctggac ttgccagcaa aaaatgtgac gattttggag ggaagtaaca
     3061 ttcacgtctt gccttccatg ccctactcag cgcaagattt ctatactagt atagacgtct
     3121 tggcggagtt agataatgga atccaagtta tcatcgaaat tcaggttcat catcagaatt
     3181 ttttcatcaa tcgcctatgg gcttatctgt gcagtcaggt taatcaaaac ctagaaaaaa
     3241 ttcgccaacg tgaaggtgat acccaccaga gctacaaaca aatcgcacta gtatacgcta
     3301 tcgcaattgt cgatagtaat tacttctcag atgacctagc ttttcatagt tttatagtaa
     3361 aatgaaatga gaacaggaca aatcgatcag gacagtcaaa tcgatttcta acaatgtttt
     3421 agaagtatag gtctactatt ctagcttcaa tctactagaa attccataga tagaaaacta
     3481 cataatctct acagatacgg atgttggagt tgatgtaaga tgctttggct tgctagagga
     3541 attgtggatt gccaaattgt atcattgaaa ttattgctca aatttgttat gatataaata
     3601 tgaataaaag tagactagga cgtggcagac acgggaaaac gagacatgta ttattggctt
     3661 tgattggtat tttagcaatt tctatttgcc tattaggcgg atttattgct tttaagatct
     3721 accagcaaaa aagttttgag caaaagattg aatcgctcaa aaaagagaaa gatgatcaat
     3781 tgagtgaggg aaatcagaag gagcattttc gtcaggggca agccgaagtg attgcctatt
     3841 atcctctcca aggggagaaa gtgatttcct ctgttaggga gctgataaat caagatgtta
     3901 aggacaagct agaaagtaag gacaatcttg ttttctacta tacagagcaa gaagagtcag
     3961 gtttaaaggg agtcgttaat cgtaatgtga ccaaacaaat ctatgattta gttgctttta
     4021 agattgaaga gactgaaaag accagtctag gaaaggttca cttaacagaa gatgggcaac
     4081 cttttacact tgaccaactg ttttcagatg ctagtaaggc taaggaacag ctgataaaag
     4141 agttgacctc cttcatagag gataaaaaaa tagatcaaga ccagagtgag cagattgtaa
     4201 aaaacttctc tgaccaagac ttgtctgcat ggaattttga ttacaaggat agtcagatta
     4261 tcctttatcc aagtcctgtg gttgaaaatt tagaagagat agccttgcca gtatctgctt
     4321 tctttgatgt tatccaatct tcgtacttac tcgaaaaaga tgcggccttg taccaatctt
     4381 actttgataa gaaacatcaa aaagttgtcg ctctaacctt tgatgatggt ccaaatccag
     4441 caacgacccc gcaggtatta gagaccctag ctaaatatga tattaaagcg actttctttg
     4501 tgcttgggaa aaatgtttct gggaatgagg acttggtgaa gaggataaaa tctgaaggtc
     4561 atgttgttgg aaaccatagt tggagccatc cgattctctc gcaactctct cttgatgaag
     4621 ctaaaaagca gattactgat actgaggatg tgctaactaa agtgctgggt tctagttcta
     4681 aactcatgcg tccaccttat ggtgctatta cagatgatat tcgcaatagc ttggatttga
     4741 gctttatcat gtgggatgtg gatagtctgg actggaagag taaaaatgaa gcatctattt
     4801 tgacagaaat tcagcatcaa gtagctaacg gctctatcgt tttgatgcat gatattcaca
     4861 gtccgacagt caatgccttg ccaagggtca ttgagtattt gaaaaatcaa ggttatacct
     4921 ttgtgaccat accagagatg ctcaatactc gcctaaaagc tcatgagctg tactatagtc
     4981 gtgatgaata agcaagaaaa aataggtctg ttagatattt gacagactta ttttttacag
     5041 aatatagtac tacttaaaaa atgttttatg ctataattga tgaataaaat agaaggagaa
     5101 gcatatgaat acctatcaat taaataatgg agtagaaatt ccagtattgg gatttggaac
     5161 ttttaaggct aaggatggag aagaagccta tcgtgcagtg ttagaagcct tgaaggctgg
     5221 ttatcgtcat attgatacgg cggcgattta tcagaatgaa gaaagtgttg gtcaagcaat
     5281 caaagatagc ggagttccac gtgaagaaat gttcgtaact accaagcttt ggaatagtca
     5341 gcaaacctat gagcaaactc gtcaagcttt ggaaaaatct atagaaaaac tgggcttgga
     5401 ttatttggat ttgtatttga ttcattggcc gaacccaaaa ccgctcagag aaaatgacgc
     5461 atggaaaact cgcaatgcgg aagtttggag agcgatggaa gacctctatc aagaagggaa
     5521 aatccgtgct atcggcgtta gcaattttct tccccatcat ttggatgcct tgcttgaaac
     5581 tgcaactatc gttcctgcgg tcaatcaagt tcgcttggcg ccaggtgtgt atcaagaaca
     5641 agtcgtagct tactgtcgtg aaaagggaat tttattggaa gcttgggggc cttttggtca
     5701 gggagaacta tttgatagca agcaagtgca agaaatcgca gcaaatcacg gaaaatcgat
     5761 tgctcagata gccttggtct ggagcttggc agaaggattt ttaccacttc caaaatctgt
     5821 cacaacctct cgtattcaag ctaatcttga ttgctttgga attgaactga gtcatgagga
     5881 gagagaaacc ttaaaaacga ttgctgttca atcgggtgct ccacgagttg atgatgtgga
     5941 tttctagaaa atcataaaaa gaattgtaca ttattctaat ttttgatata atagtcagca
     6001 ggaaagaaag tcttatggcg ttcttcaagc gagcttggga cagtgggagc caagtagggc
     6061 aaaataatga gctggcgctt tctgtagtat tttcaaaaac aatgaagtaa taaattaggg
     6121 tggaaccgcg tttctgacgc ccctaggtta aatcaaccta ggattgtcag atgtggttct
     6181 tttgcttatt cagtctattg tgtgaaagaa aggagagccg tggacaacct ttatcttgta
     6241 aaagacgata gtcaactagc tacatttcgt gattttgtag taagaaatac tgaaaagttg
     6301 aaagattatc aatctttttt aaagaatgaa cttgcagtct gtgatttacc gcaagccgtt
     6361 atttggtcag attttaatgc tgctacacag attattaggg aaagcgctgt tccagcctat
     6421 acaaataata gacgaatggt tatgactctt atatctggtt cgaagagggg atggttgaat
     6481 atattagtcg caagtatttc ttgacagaag aggaatttca agcggaaaaa atttgtaatc
     6541 aatctctcgt agaacttttt cagaagaagt atagttggca ttcattgaat gattttggtt
     6601 cttcgactta tgataagaac tatgcaagta ttttttatga atactggcgc agctttttga
     6661 cagtagataa gttggtagaa aatttaggta gtgtacaagc ggtcttagat tcttatcatt
     6721 tatgggcaaa tacagaaaaa acttttccct tgttagattg gtttgttcag cagaaattaa
     6781 ttgaaaaaga aatataaaaa ctaaaggagt aaacaatgtc taagaaattg acatttcact
     6841 gcatcagtgg caga
//
LOCUS       DAVBOU010000077         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBOU010000077 DAVBOU010000000
VERSION     DAVBOU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.078"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ879_002004"
     CDS             138..860
                     /locus_tag="VQ879_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3144098.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ879_002005"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ879_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3144099.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ879_002006"
     CDS             complement(2467..3378)
                     /locus_tag="VQ879_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3144100.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ879_002007"
     CDS             complement(3402..4205)
                     /locus_tag="VQ879_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3144101.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ879_002008"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ879_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3144102.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ879_002009"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ879_002009"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3144103.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1388 c         1478 g         1843 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgatatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBOU010000078         6720 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBOU010000078 DAVBOU010000000
VERSION     DAVBOU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6720
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.079"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..306
                     /locus_tag="VQ879_002010"
     CDS             <1..306
                     /locus_tag="VQ879_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3144104.1"
                     /translation="APMTYEETMTSDFFEAWFQNFLLPTLTTPSVIIMDNVRFHRMGK
                     LELLCEEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            367..1329
                     /locus_tag="VQ879_002011"
     CDS             367..1329
                     /locus_tag="VQ879_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3144105.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1507..2514
                     /gene="gap"
                     /locus_tag="VQ879_002012"
     CDS             1507..2514
                     /gene="gap"
                     /locus_tag="VQ879_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3144106.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2581..3417)
                     /locus_tag="VQ879_002013"
     CDS             complement(2581..3417)
                     /locus_tag="VQ879_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3144107.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3543..5738
                     /locus_tag="VQ879_002014"
     CDS             3543..5738
                     /locus_tag="VQ879_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3144108.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEELVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5791..5943
                     /gene="rpmG"
                     /locus_tag="VQ879_002015"
     CDS             5791..5943
                     /gene="rpmG"
                     /locus_tag="VQ879_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3144109.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5953..6129
                     /gene="secE"
                     /locus_tag="VQ879_002016"
     CDS             5953..6129
                     /gene="secE"
                     /locus_tag="VQ879_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3144110.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6184..6720
                     /gene="nusG"
                     /locus_tag="VQ879_002017"
     CDS             6184..6720
                     /gene="nusG"
                     /locus_tag="VQ879_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3144111.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2088 a         1183 c         1446 g         2003 t
ORIGIN      
        1 gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagcttg gtttcagaat
       61 tttctcttac caacattaac cacaccatcg gttattatta tggataatgt aagattccat
      121 agaatgggga agctagaact tttatgcgaa gagtttgggc ataaactgtt acctcttcct
      181 ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc
      241 aaaaaggtat taccaagttg caataccttt tacgaggctt ttttatcctg ctcttgtttc
      301 aattgactat atatcacgga tacagttggg aaagaagcta ttaaatattt ggagagtcct
      361 tttgggatga acatgtcaaa tattactata gatgggcaag aaatagatct gagtcaaacg
      421 atgccttctt atgctcaagt agtgagtctt tatgatgata caagtatctc tgttagtagt
      481 aatgagacgg acaaagtgtt ggctggatcc ctctatactg atacaaatga acagggatta
      541 acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa tttgacagct
      601 aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc cgaaactagt
      661 aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga tgacatggag
      721 gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga ggctggattt
      781 acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac aaaagtagta
      841 acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag agttcttgat
      901 attgtgatta cctttattcg tgttattcag ggattattga ttgtgctttc atcacaagct
      961 attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat gcaacgttct
     1021 aaggaaatag gtgtcatgaa ggcagttggt tatcagaatc gtgatgtcaa aggaattttt
     1081 atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt ggttgcacaa
     1141 ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat cactaaggtt
     1201 tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt acttggttat
     1261 gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctgtaga accgttacgc
     1321 tatgaatagt aagggattcc ttgatttaca gtcttaaaaa agaaactaac atagaaaaac
     1381 aatggccata cttgcaattc aactcaaata gttgtataat aggtttgttg aaaggtgatt
     1441 tgtagtgatt caagttactc ttttcacaat aaaaatttca tgattttcat aaggaggaaa
     1501 tcactaatgg tagttaaagt tggtattaac ggtttcggac gtatcggtcg tcttgctttc
     1561 cgtcgtatcc aaaacgtaga aggtgttgaa gttacacgca tcaacgacct tacagatcca
     1621 gttatgcttg cacacttgtt gaaatacgac acaactcaag gtcgtttcga cggtactgtt
     1681 gaagttaaag aaggtggatt tgaagttaac ggtaaattcg ttaaagtttc tgctgaacgt
     1741 gatccagagc aaatcgactg ggctactgac ggtgtagaaa tcgttcttga agctactggt
     1801 ttctttgcta agaaagaagc agctgaaaaa caccttaaag gtggagctaa aaaagttgtt
     1861 atcactgctc ctggtggaaa cgacgttaaa acagttgtat tcaacactaa ccacgacgtt
     1921 cttgacggta ctgaaacagt tatctcaggt gcttcatgta ctacaaactg cttggctcca
     1981 atggctaaag ctcttcaaga taactttggt gttgttgaag gattgatgac tactatccac
     2041 gcttacactg gtgaccaaat gatccttgac ggaccacacc gtggtggtga ccttcgccgt
     2101 gctcgcgctg gtgctgcaaa catcgttcct aactcaactg gtgctgctaa agctatcggt
     2161 cttgtaatcc cagaattgaa cggtaaactt gacggatctg cacaacgcgt tccaactcca
     2221 actggatcag ttactgaatt ggtagcagtt cttgaaaaga acgttactgt tgatgaagtg
     2281 aacgcagcta tgaaagcagc ttcaaacgaa tcatacggtt acacagaaga tccaatcgta
     2341 tcttcagata tcgtaggtat gtcttacggt tcattgtttg acgcaactca aactaaagtt
     2401 cttgacgttg acggtaaaca attggttaaa gttgtatcat ggtacgacaa cgaaatgtca
     2461 tacactgcac aacttgttcg tactcttgaa tacttcgcaa aaattgctaa ataattcttg
     2521 agttgataga aagcaaggct ttgtggtctt gctttttata tagaaaaatg gatgacacga
     2581 tcatccattc ttttttaatt ctttttcaaa tgtatttgaa agggtagtga aagttagcct
     2641 ctctaaagta agtgggtggg taaaggaaag tcggaaggca tgaagcataa gccggcttgt
     2701 ctttgattta ctattataga gagggtctcc caggatagga agattatgat gcaaaaggtg
     2761 cacacgaatc tgatgggttc gccctgtctt tagcttgcaa tgagccaagg aagtcttgtt
     2821 tgagaattgc tttaatctgc ttacatgcgt ttcagcatat tgcccatttt ttgcatcaac
     2881 tattcttttt ctacgatcat ggcgatcacg tccaattttg tctctgaaaa caagttcttt
     2941 tctgttgata tttccatcaa ctagagccca atattctcta gaaatctctt ttttctccaa
     3001 taagcgattg agaatgggca ggataaaagg atttttggca aagagaacta agccactggt
     3061 ttccatgtcc agacgatgaa cgacatagca ggtttggcca acataggtac tgacatggtt
     3121 aagaagggca atttcgtttg gttgattacc atgcgttttc atcccctctg gtttgtttac
     3181 aataatcaag tgttgatctt gataaacttc ctgcactaag tctgggttgc cccaagggat
     3241 cgtcttttgg ggataatctt cctcgtcaaa agtcaactgg caaacatctc caggatttac
     3301 gatttcgttc cagtggactt cttcttgatt tatcaaaata tgtttcttga ttctcaaaaa
     3361 atgacggatt tttctaggga tgaggagttg ttcctcaagt aattgcttta ccgtcatttg
     3421 aggtatagag gcgggtaatg taaatgtgaa ttgcatacag atattgtaac aaaaaaagcc
     3481 ctatttggat aggaaatagc taaattcttg tcttcctatg atgaagatga taaaataaac
     3541 gcatgaaatt agataaatta tttgagaaat ttctttctct ttttaaaaaa gaaacaagtg
     3601 aactagagga ctctgattct actatcttac gtcgctctcg tagtgatcga aaaaaattag
     3661 cccaagtagg tccgattcga aaattctggc gtcgttatca tctaacaaag attatcctta
     3721 tactaggttt gagtgcaggc ttgctagttg gaatctattt gtttgctgta gccaagtcga
     3781 ccaatgtcaa tgatttgcaa aatgccttga aaactcggac tcttattttt gaccgtgaag
     3841 aaaaagaggc tggtgccttg tctggtcaaa agggaaccta tgttgatctg actgatatca
     3901 gtaaaaactt gcagaatgct gttattgcga cagaagaccg ttctttctat aaaaatgacg
     3961 ggattaacta tggccgtttc ttcttggcta ttgtcactgc tggacgttca ggtggtggct
     4021 ctaccattac ccaacagctg gctaaaaacg cctatttatc acaggatcaa actgttgaga
     4081 gaaaagcgaa agaatttttc cttgccttag aattaagcaa aaaatatagt aaggagcaaa
     4141 ttctaaccat gtaccttaac aacgcttatt ttggaaatgg tgtgtggggt gtagaagatg
     4201 cgagtaagaa atactttgga gtttctgcat cagaagtgag tctggatcaa gctgcgactc
     4261 tggcagggat gctcaagggg ccggaactgt ataatccctt gaattccgta gaagattcta
     4321 ctaatcggcg cgatactgtc ttgcagaata tggttgcagc aggatatatt gataaaaacc
     4381 aagaaaccga agctgctgaa gttgatatga cttcgcaatt gcacgataag tatgaaggaa
     4441 aaatctcaga ttaccgttac ccctcttatt ttgatgcggt ggttaatgaa gctgtttcca
     4501 agtataatct aacagaggaa gagcttgtca ataatggcta ccgcatttac acagagctgg
     4561 accaaaacta ccaagcaaat atgcagattg tttatgaaaa cacatcgcta tttccgaggg
     4621 cagaggatgg aacgtttgct caatcaggaa gtgtagctct cgaaccgaaa acagggggag
     4681 ttcgtggagt tgtcggtcaa gttgctgaca atgataaaac tggattccgg aatttcaact
     4741 atgcaaccca atcaaagcgt agtcctggtt ctacaattaa gcctttagtt gtttatacgc
     4801 cagcagttga agcaggctgg gctttgaata agcagttgga taaccatacc atgcagtatg
     4861 acagctataa ggttgataac tatgcaggga tcaaaacgag tcgagaagtt cctatgtatc
     4921 aagccttggc agaatcgctt aatctacctg ctgttgccac tgttaatgat ttgggtgtcg
     4981 acaaggcttt tgaggcaggc gaaaaattcg gactcaacat ggaaaaggtc gaccgtgttc
     5041 ttggtgtcgc cttgggaagc ggtgttgaaa ccaaccctct tcaaatggct caagcatacg
     5101 ctgcctttgc aaatgaaggt ttaatgcctg aagctcattt tattagtaga attgaaaatg
     5161 ctagtggaca agttattgcg aatcataaaa attcacaaaa acgggtgatt gataagtctg
     5221 tagctgacaa gatgaccagt atgatgttgg ggactttcac caacggtacc ggtattagtt
     5281 catcgcctgc agactatgtc atggcaggga aaactggaac aactgaagca gttttcaatc
     5341 cggagtacac aagtgaccag tgggtaattg gttatactcc ggatgtagtg attagccact
     5401 ggcttggctt tccgaccact gatgaaaatc actatctagc tggctctact tcaaacggtg
     5461 cagctcatgt ctttagaaac attgccaata ccattttacc ttatacgcca ggaagtacct
     5521 ttacggttga aaatgcttat aagcaaaatg gaattgcacc agccaataca aaaagacaag
     5581 tacaaaccaa tgataatagc cagacagatg ataatttgtc tgatattcga gggcgtgcgc
     5641 aaagtctagt agatgaggct agccgggcta tctcagatgc gaagattaag gaaaaggctc
     5701 aaacaatatg ggattcgata gtcaatctat ttcgctaaga tgcttgtcaa agcctagctt
     5761 tcttgttata atggataaga tggaggcgtt atggcactaa aaaaagcaag cctagcttgt
     5821 gcggtttgtg gttcgagaaa ctattcaatc aagatcagcg gaaaccccaa gcctacacga
     5881 ctagaagtaa ataaattttg taagcattgt ggcaagtaca ctacacacag agaaacgaga
     5941 taggagagag cgatgcgttt tattggagat atttttagac ttcttaaaga cacaacatgg
     6001 ccaactcgca aggaaagctg gagagatttt cgttctatca tggaatacac agctttcttt
     6061 gtagtaatta tttacatttt tgaccagttg attgtttcag gtttgattcg atttattaac
     6121 attttttaga agattagtgg agttaattac actagaaatc ttctatttat gaaaggaaat
     6181 atcatggata gttttgataa aggatggttt gttttacaaa cttattctgg ttatgaaaat
     6241 aaggtgaaag aaaatctatt acaacgtgca caaacctaca atatgttgga taatattcta
     6301 cgcgttgaaa ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag aaaagaagta
     6361 gaagaaaatc gctttccagg ttatgttctt gtagaaatgg tcatgacaga tgaagcttgg
     6421 tttgttgttc gaaacacacc aaatgttaca ggatttgtcg gatcacacgg gaacagatca
     6481 aaaccaactc cattattgga acaagaaatt cgtgacattt tggtatctat gggacaaact
     6541 gttcaagaat ttgatttcga tgttgagatt ggtcaaactg tacgtattat tgatggtgct
     6601 tttgcagact acactggtaa gattacagaa attgataata acaaagtgaa aatgattatc
     6661 tctatgtttg gtaatgacac agttgcagaa gtaaacctaa accaaatcgc agaattataa
//
LOCUS       DAVBOU010000079         6627 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBOU010000079 DAVBOU010000000
VERSION     DAVBOU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.080"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ879_002018"
     CDS             170..370
                     /locus_tag="VQ879_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144112.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ879_002019"
     CDS             412..816
                     /locus_tag="VQ879_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144113.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ879_002020"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ879_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3144114.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ879_002021"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ879_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3144115.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ879_002022"
     CDS             2697..4088
                     /locus_tag="VQ879_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3144116.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ879_002023"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ879_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3144117.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ879_002024"
     CDS             5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ879_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3144118.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT         2032 a         1215 c         1411 g         1969 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     6541 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt
     6601 ctcaagtgat aaagtcaagt tagtgga
//
LOCUS       DAVBOU010000080         6206 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBOU010000080 DAVBOU010000000
VERSION     DAVBOU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.081"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ879_002025"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ879_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ879_002026"
     CDS             1555..2427
                     /locus_tag="VQ879_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3144119.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ879_002027"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ879_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ879_002028"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ879_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ879_002029"
     CDS             3376..4092
                     /locus_tag="VQ879_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3144120.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ879_002030"
     CDS             complement(4222..5037)
                     /locus_tag="VQ879_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3144121.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ879_002031"
     CDS             complement(5034..5939)
                     /locus_tag="VQ879_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3144122.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         1961 a         1073 c         1249 g         1923 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagta
//
LOCUS       DAVBOU010000081         5901 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBOU010000081 DAVBOU010000000
VERSION     DAVBOU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.082"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            61..1887
                     /gene="glpO"
                     /locus_tag="VQ879_002032"
     CDS             61..1887
                     /gene="glpO"
                     /locus_tag="VQ879_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3144123.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1957..2661
                     /locus_tag="VQ879_002033"
     CDS             1957..2661
                     /locus_tag="VQ879_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3144124.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            2958..3161
                     /locus_tag="VQ879_002034"
     CDS             2958..3161
                     /locus_tag="VQ879_002034"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144125.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(3248..3508)
                     /locus_tag="VQ879_002035"
     CDS             complement(3248..3508)
                     /locus_tag="VQ879_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144126.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(3563..3907)
                     /locus_tag="VQ879_002036"
     CDS             complement(3563..3907)
                     /locus_tag="VQ879_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144127.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            4943..>5901
                     /gene="ltrA"
                     /locus_tag="VQ879_002037"
     CDS             4943..>5901
                     /gene="ltrA"
                     /locus_tag="VQ879_002037"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3144128.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         1835 a         1142 c         1295 g         1629 t
ORIGIN      
        1 agattttcga agagtataat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat
       61 atggaatttt caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgcaccctg
      121 gacctcttga ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct
      181 agcggtcttg agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt
      241 tcaacaaaat tggttcacgg aggtcttcgc tacctcaaac aattcgacgt agaggtggtc
      301 tcagatacgg tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaacca
      361 gatccaatgc tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt
      421 aaagtagcca tggacttgta cgacctttta gcaggtgtga gcaacacacc aactgcgaac
      481 aaggttttga gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg
      541 gtaggaggtg gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac
      601 atcaaacgtg ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc
      661 ctctttgacg aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa
      721 gtatttgaaa tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta
      781 cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac
      841 ttggtagtgg attcaagcaa aatcaaggtt tcacagccag tttactttga cacaggtttg
      901 ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact
      961 gatacagact acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat
     1021 ctacttggca ttgtcaacaa ccgctttcca gaatccaaca tcaccattga tgatatcgaa
     1081 agcagctggg caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt
     1141 ggaaataacg gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct
     1201 tatctctcca aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt
     1261 agcacatctg agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt
     1321 gatgacaatg gtctcttgac tcttgctggt ggtaaaatca cagactaccg taagatggct
     1381 gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa
     1441 ttgatcaatt ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat
     1501 tcagaaatcg aagcctttgc gcaacttgga gtttcacgtg gtttggatag caaggaagct
     1561 cattacctag caaatcttta cggttcaaat gcaccgaagg tctttgcact tgctcacagc
     1621 ttggaacaag cgccaggtct tagtttggca gacaccttgt cccttcacta tgcaatgcgc
     1681 aatgagttga ctcttagccc agttgacttc cttcttcgtc gtaccaatca catgctcttt
     1741 atgcgtgata gcttggatag tatcgttgag ccagttttgg atgaaatggg acgattctat
     1801 gactggacag aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac
     1861 aacgatttag cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct
     1921 tgtcgcccgt cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa
     1981 tttctaggga ctttaattct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt
     2041 cctaaaacca agagcaatag ctcaggttgg attgtgatta ctatgggttg ggggattgca
     2101 gttgcggttg cagtctttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg
     2161 accatcggtg tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta
     2221 gcccagttcg caggggccat gctgggtcag attttggttt ggttgcaatt caaacctcac
     2281 tatgaggcag aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc
     2341 aaggatactg tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca
     2401 atctttgctt tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact
     2461 ttgattgtcg gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct
     2521 cgtgaccttg gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga
     2581 gactggtctt acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg
     2641 cttgtattct cacttttcta gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg
     2701 tcgccttacc gtactcaagt acagcttgcg gctagcttcc tagtttgctc tttgattttc
     2761 attgagtatt agaaaacaat tatgttgata gagcttgggc aagagcccaa tttcagcaaa
     2821 aaatgaagta aatcttctca taataaaacg catcatatca agcacgaaaa ttccacgagg
     2881 tcaactacag tcagaaagct gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc
     2941 aagcacctgc aagcaacgtg ccgaaatggt caaatcctga ttatgtcaac gaattagacc
     3001 caaaaatcgt tgatatgcta gtagaatttc acaagtcaca aggcactttg gaaactcccg
     3061 aggcgcaagc agaaatcgcc caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg
     3121 aggataaaaa acaagagctt ttgaaccgct tgaacaaata gagtttcgca agtattatgc
     3181 ttacaaatta cttgagcaat taactaaaat ataaaccctg cctttatatc taggcagggt
     3241 ttatatttta gaaattcacg taggttgtta cggtttttac atacccagta tagtttgagt
     3301 ttctatagta ttcagtgata aacttccatt ttctttgagc aacatggata taagtacttg
     3361 ttatgtagta tggatatggg ctttgtgaat ccaagtaaga ctgataagct tgtataccaa
     3421 aatatgctcc accaattatt gcaccccatg gaccccccaa taaagcacct atcctaccaa
     3481 tcatataact gattccagca ccagtcatga agttagcgaa tgtgttagct tgtttattcc
     3541 catgtattgt gttgacgtaa tttcaaacat taggatcgta tgatctaaaa gatatattta
     3601 ggtcgatttc attcttttga taagccatat aaaatgcccc attgatatag acgccgtcag
     3661 cacgtcgttc aatagtgtct acacttccat ctggattgac aacctcaaga acttcatcgc
     3721 ttaaaatatt tacttgcgta tctccgaacc gcactgatga gccattctca aactgagcct
     3781 caccagatac aactttagag tttgccgata agctatcatc agcaaaaaca acaagcgacg
     3841 gggaaatgct agacatacag aaaacagaca taactagcaa acacatgcat ttaaacatct
     3901 tagacataac ggaaactctt ttgtattttt gatttttttc aacttttatt atacaataaa
     3961 accaaataaa aagaaagcgg taacaatatg cttaatgcga aaatttttta tatattttta
     4021 tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga aaagaggtct cgaaatgggt
     4081 tatttagaca cagaagctat tatcctcgca gttttttcat ttgcttttta caacctatgt
     4141 tcattcgctt gggtctgctc tacaataaaa aacaataaaa aataaataga cgtattttca
     4201 aaaaaaaaaa tgcatactta tcttagcaaa atgacgattt aaatcgtcgt ttttttgtag
     4261 tacgacgggc atgtcgtata tctgaggtgt aagtcctcgg tgggcacctg ctaccggtga
     4321 acccaatagc gattcccaag cctgactatc gtgaggtagc agggagagga agggatagcg
     4381 aaatcgtggc tctacgaaca ggaacgtgat agtaaggcgt atatagcgga taaggaggct
     4441 tcaaactcta aagtccaaaa aggtagtcgt aacctatatg tgtaaatcac gagagtaatt
     4501 gaattcggac taaggtttgt gtgaaaaaga taaatctttc tagagtctaa agactctgcg
     4561 tcagatttcc tattttcact gtaacctttt aacgtcctca tatcttgtat aaacgaggaa
     4621 agatgtacga cttatcccgt gaggtttcat gagcgctgaa agcgtagtaa caacgaatca
     4681 tgagaagtca gccgagccca tagtagtgag gaaacttctg tagtggaagt ggagcgacgg
     4741 ggtgaatact caaacagtct ggggagagac tgtttgaggt ctgtcgctag aaagagaaaa
     4801 cgacagatcg aagtaatcct acttcacttg tgtctgtaaa atgagtggtc tgatagaact
     4861 ggactttgac acgtaatgac tagatgaagg ttcaccaata taagatgtcc ctcaggcacc
     4921 aaaacaagaa aggaataggc acatgtcaaa actgctagat aagatattat cacgcgaaaa
     4981 tatgctggaa gcctacaatc aagtaaaatc caataaaggc tcagctggga ttgatggaat
     5041 gactatcgaa gagatggata attatctcag acaaaactgg cgcttgacta aggaactgat
     5101 aaaacagaga aaatataagc ctcaaccagt tcttaaagtt gagataccta aaccagacgg
     5161 aggcatccgt caactaggaa ttccaacagt tatggataga atgattcaac aggccattgt
     5221 ccaagtcatg agccccattt gtgaacccca tttctcagat acgagttatg gtttcagacc
     5281 aaataggtca tgtgaaaaag ccatcatgaa gctcttagaa tacttaaatg acggctatga
     5341 gtggatagtg gatatagacc tagagaaatt tttcgataca gttcctcaag atagattgat
     5401 gtccttagta cataacatta tcgaagacgg agatacggaa tccttgattc gtaagtatct
     5461 tcattcaggt gttatcatta atggtcaacg ttataaaaca ctagttggta caccacaggg
     5521 aggaaattta tctcctctct tatccaatat catgcttaat gaattggaca aggaattaga
     5581 aaagagggga cttcgatttg tgcgctacgc agatgattgt gtgattacgg tcggaagcga
     5641 ggcagcctct aagcgtgtga tgtattcagt cagtcgtttt attgagaaac ggctaggttt
     5701 gaaagtaaac atgaccaaga ctaagattac cagaccaaga gagttgaaat atctaggttt
     5761 tgggttctgg aaatcatcag atggttggaa aagccgtcca catcaagata gtgttcggag
     5821 atttaagttt aaattgaaga aactaacaca gaggaaatgg agtatagacc taacaagacg
     5881 tattgagcaa ctgaatttgt c
//
LOCUS       DAVBOU010000082         5483 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBOU010000082 DAVBOU010000000
VERSION     DAVBOU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5483
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.083"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..1158
                     /locus_tag="VQ879_002038"
                     /pseudo
     CDS             1..1158
                     /locus_tag="VQ879_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            1182..1338
                     /locus_tag="VQ879_002039"
                     /pseudo
     CDS             1182..1338
                     /locus_tag="VQ879_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1331..1504)
                     /locus_tag="VQ879_002040"
     CDS             complement(1331..1504)
                     /locus_tag="VQ879_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3144129.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(1663..3270)
                     /locus_tag="VQ879_002041"
     CDS             complement(1663..3270)
                     /locus_tag="VQ879_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3144130.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            3423..4907
                     /locus_tag="VQ879_002042"
     CDS             3423..4907
                     /locus_tag="VQ879_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3144131.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            5002..>5483
                     /locus_tag="VQ879_002043"
     CDS             5002..>5483
                     /locus_tag="VQ879_002043"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3144132.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1623 a         1239 c         1005 g         1616 t
ORIGIN      
        1 gaagaaatat gactttcaaa aaccttctaa aattccttat cttgaaacaa ctggtatgcc
       61 tactagaatt ctccttagaa agcgtcgctt taagtgctat cactgttcaa aaatgatggt
      121 cgctgaaact tctatcgtca agaaaaatca ccaaattcct cgtattatca accaaaaaat
      181 tgcgcaaaag ttaattgaaa agaattctat gaccgatatt gcccatcagc tggccatctc
      241 aacttcaact gttattcgta agctcaatga ttttcacttt aaacatgatt tttcttgtct
      301 tcctgagatt atgtcttggg atgagtatgc ttttacaaag ggaaagatga gcttcattgc
      361 gcaagatttt aacaagctca atatcatcac tgttcttgag ggaagaacac aagctatcat
      421 tcgaaatcac tttcttcgct acgatagagc tgtccgatgt cgcgtcaaaa ttattactat
      481 ggatatgttt agcccttact atgacttagc taaacagctt cgctttcaaa tttctaggct
      541 caggctgaaa cagtctccta gactgtttca ctcccgaatg ctaaaatcgt tcttgatcgc
      601 tttcatattg tacaacatct tagccgtgct atgagtcgtg tgcgtgttca aatcatgaat
      661 cagtttcatc gaaaatccca tgaatacaag gctatcaagc gctactggaa gctcatacaa
      721 caggatagtc gtaaactcag cgataaacat ttttatcgcc ctacttttcg tatgcattta
      781 accaataaag agattttaaa caagcttttg agctattcac aagacttgaa acatcactat
      841 cagctctatc aactcttgct gtttcacttt cagaataagg aaccggagaa atttttcgga
      901 ctcattgagg acaatcttaa gcaggttcat cctatttttc agactgtctt taaaaccttt
      961 ctaaaggaca aagagaaaat agtcaacgcc cttcaactac cctattcaaa cgccaaattg
     1021 gaagcgacca ataatctcat caaacttatc aagcgcaatg cctttggttt tcggaacttt
     1081 gaaaacttca aaaaacggat tttcatcgct ctgaacatca aaaaagaaag gacgaaattt
     1141 gtcctttctc aagcttagct tttcttcaac ccactacagt tgacaaagag cctaagcttt
     1201 tacctcttcc tccctactca cctgagtaca atcctattga gaaaacatgg gctcatatca
     1261 aaaagcacct cataaaaggt attaccaagt tgcaatacct tttatgaggc tcttttgtct
     1321 tgttcttgtt tcaattgact atattatcag tgtaatagtc taatagatag ttaaatgtag
     1381 ttggatttcc actaaaggtt gatgagtaag tttttgtatc tgaacctgat tggccgcaag
     1441 cagctaaaag caaaacagat gcaaaagtca ggcctgcact aaggacacgc ttctttatgt
     1501 tcatcttctt tctccttaat agtgggaatt tgtaaagtta attgaatttc gagaatgaaa
     1561 gtttataaac cttggttata aaaaacaaag gatttctgct ttttatacag tcctcccttg
     1621 tttttatatg atttcaattt taaatttttc tgcaaaaaat atttatagta attccacaca
     1681 gaaagcatcc catggaacta agatttgttt ttcaaagact tcttgagcta gggtgttttc
     1741 aatcaagaca gatttgactt ttccttctac tgtcaagtct tgctcttcat tggacaagtt
     1801 agccacaact aggaagcgac ggtcgccatc cttacgtata taagcaaaga ccttatcagc
     1861 cgtatcaagc aattcaaagt cagctcgaac tagccagcta ttctccttgc gaatttggac
     1921 cagtttctga taggtataga aaatagaatc tggatttgcc agcgcttctt ggacattgat
     1981 catctcgtaa tttggattaa ccgccaacca aggttgacct gttgagaaac cagcgttttt
     2041 gctctcgtcc cattgcatag gggtacgggc attgtcacgt ccaataacac ggatactgtc
     2101 catgatttct tcaatcggaa cacctttttc aagagcctca cgcgcatagt tgagagattc
     2161 aatatcttct acttgatcca gcgtttcaaa gggatagttg gtcatgccaa tttcctcacc
     2221 ttggtagata taaggagttc ctctcatgag atgaagcaag atggcaaagg ctttggcaga
     2281 tttttcgcgg tattcttggt catttcccca gattgagaca atacgaggga ggtcatggtt
     2341 gttccagaag agggaattcc agccgtcctc aactcctaac tctgtctgcc atttgttgaa
     2401 gatttctttt aacttagcga tattcagctc tttttgatag tgccatttag gctgaccttc
     2461 ctgatactga agaccgatat gttcaaactg gaagaccata gacaattctt gcccctttgg
     2521 atcagagtag agcttggcaa tctctggcgt tgctccccaa gtctccccta ctgtcaagag
     2581 atccttatct ccaaaggtcg cctgattcat ttccttgaga tagggatgga gcataggacc
     2641 attattgact accttctcgt caggaatttt gccaatcatg tcaataacat ccatacggaa
     2701 accaccaata cccttatcaa tccagaagtt catcatctca taaattttct ggcgaagttt
     2761 ttcattttcc cagttgagat ccggctgttt cttgctgaaa aagtggagat agtattgacc
     2821 tgacttttca tcgtattccc aagcagaccc actaaagata gaatctaggt cattgggttc
     2881 atcgcgccag atatagtagt ctcgctcagg gctattagga ttttcacagg cctctacaaa
     2941 ccaggcatgc tcatccgagg tatgattgac caccaagtcc atgatgatac ggatatcacg
     3001 cttcttagct tctgcaatca gttgatccat atcctccatg gttccaaaaa tcgttgcaat
     3061 cgcttgataa tcagcaatat cgtagccatt atcatccata gggctgtcat aaacgggaga
     3121 aagccaaatt gctgtgattc ctagcttggc tagatagtcc aacttactgg taattcctgg
     3181 caaatcgcca attccatctc cattactatc cataaaactc tttggataga cttgatagac
     3241 tacggcattg tgccaccatt tttcttgcat cttcttacct cattattttc ataatctata
     3301 gtctatgata gcacttttta aaattttgtg caagcgtttg cttaatcttt ttaatttctt
     3361 ttttagctcc gtagtttcct aacttccaat tttttattat aatagagtcc agaggtaaaa
     3421 aaatgaaaaa acaagctttt agttctgaac aatatttgaa tttacaacgc gaccatattt
     3481 tggagcgcat taaccaattt gacggcaagc tctacttaga gtttggcggt aaaatgttag
     3541 aagatttcca cgctgctcgt gtccttcctg gttatgaacc tgacaacaaa atcaagctct
     3601 tgcaagaatt gaaagagcag gttgaggttg tgattgccat taatgctagc aacattgaac
     3661 attccaaagc acgtggcgac ttaggcattt cttatgacca agaagttctt cgtttgattg
     3721 acaaattcaa tgaattaggg atttttgttg gttccgttgt cattacacaa tacgctggcc
     3781 aacccgctgc agatgccttc cgcaatcaac ttgagaaaaa cggaattgat tcttatcttc
     3841 attatccaat caaaggatat ccgacggata tggatcacat catttcccca gaaggcatgg
     3901 gcaaaaacga ctacatcaaa accagtcgca acttgattgt cgtaaccgct cctggacccg
     3961 gttctggaaa attggcaacg tgtatgtcca atatgtacca cgaccaaatc aatggcatca
     4021 agtctggcta cgctaaattt gaaaccttcc ctgtttggaa tcttcccctt catcacccag
     4081 ttaacttggc ttatgaagct gccacagctg accttgatga tgtcaacatg attgacccct
     4141 tccatcttca aacctatgga gaaaccactg tcaactacaa ccgtgatatc gaaatcttcc
     4201 cagtgctcaa gcgcatgttg gaacgtattc tcggaaaatc accatacgct tcaccgacag
     4261 atatgggtgt caacatggtt ggtttcgcta ttacagatga cgaggctgct gtcgaagctt
     4321 ctaaacaaga aatcatccgc cgttactatc aaacagttct tgacttcaaa gctgaaaaag
     4381 ttggcgaagc tgccgtcaag aaaattgagt tactcatgaa cgacctcggt atcacacctg
     4441 cagaccgtaa ggttgctgtc gttgcgcgcc aaaaagcaga agaaactggt ggaccagccc
     4501 tagcctttga attgccaaat ggggaaatca tcactggtaa gaactcagaa ctctttggcc
     4561 ctacagccgc tgccttgatc aatgccatca aaaaatcagc tgacatcgct aaagaagtaa
     4621 aactaatcga gcctgaagtt gttaagccaa tccaaggtct taaaatcgat catctcggta
     4681 gccgcaatcc acgccttcat tcaaatgaaa tcctgattgc acttgctatc acagctacag
     4741 aaaatcctga tgctgcccgc gctatggaag aactcggcaa cctcaaagga agcgaagccc
     4801 actcaaccat catcttgact gatgaagaca agaatgtcct tcgtaaactg ggtatcaacg
     4861 taacctttga cccatactac caatacgacc gcttatatcg taagtaaaga tttcaacctc
     4921 tccagcctcg gagaggtttt ctctctgtct caggagcaac ctttatgata taatgagaga
     4981 agaaaactga aaggatttac catgtcaaaa gaagttattg tcgaaagttt tgaacttgac
     5041 cacaccattg tcaaagcacc ctatgttcgc ttgattgggg aagaaacagg accaaaagga
     5101 gacatcatct ccaattatga tattcgcttg gtgcaaccaa acgaagactc tatccctact
     5161 gccggccttc acactatcga gcacctctta gccaaactca tccgtacccg cattgacggc
     5221 atgattgact gttcaccatt tggttgccgc acaggcttcc acatgattat gtggggacgt
     5281 cacaccagtg ctaaaatcgc agctgttatc aaggattcgc tcaaggaaat cgctgaaact
     5341 actacttggg aagatgtccc agggacaacc atcgaatctt gcggaaacta caaggaccac
     5401 agcctcttct ctgctaaaga atgggcaaaa ctcatcttgg aacaagggat ttcagatgat
     5461 gcctttgaac gtcatgtgat tta
//
LOCUS       DAVBOU010000083         5446 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBOU010000083 DAVBOU010000000
VERSION     DAVBOU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5446
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.084"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ879_002044"
     CDS             complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ879_002044"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3144133.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1663..3090)
                     /locus_tag="VQ879_002045"
     CDS             complement(1663..3090)
                     /locus_tag="VQ879_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3144134.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3255..4127
                     /gene="hslO"
                     /locus_tag="VQ879_002046"
     CDS             3255..4127
                     /gene="hslO"
                     /locus_tag="VQ879_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3144135.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4114..5094
                     /gene="dusB"
                     /locus_tag="VQ879_002047"
     CDS             4114..5094
                     /gene="dusB"
                     /locus_tag="VQ879_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3144136.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(5324..>5446)
                     /locus_tag="VQ879_002048"
     CDS             complement(5324..>5446)
                     /locus_tag="VQ879_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144137.1"
                     /translation="KASQWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         1572 a         1289 c         1067 g         1518 t
ORIGIN      
        1 catcgatttc cgcaaagact tgagttgctt tcacagcctt cttccagccc ttgtagagtt
       61 gttccttgcg agattcgttc atagatggct caaagagttc tcctgtctcg ttcaagagtt
      121 tcaactcgtc caagtctttc cagtacccta ctgacaaacc tgctaggaag gccgctccta
      181 gagctgttgt ttccaagttt ttagcacgtg caatgtcaat gcctaaaata tccgcctgga
      241 actgcatgag gaagttgttc atggctgcac caccatccac cttcagtact tgaatggcgg
      301 tctgagtatc catttgcatg gtgtcgatga tgtcacgcac ttgataagca atagattgca
      361 aagtcgcctt gataaagtct tctttgcttg ttccacgagt caaaccaaag acggaaccac
      421 gagcattttg gttccagtat ggagcgccta gacctgtaaa ggctggaacg acataaactt
      481 catcgttgtt gtgagaatca cgagcgtatt tttcagattc tggtgaattt tcaaccatgc
      541 gaagaccgtc acgaagccac tgaatagcac ttcctgcgat gaagatagaa ccttccaagg
      601 cataataaac cttaccgttg attccgtaac caatggttgt caagaggttg ttttcagaca
      661 actgcatctc ttccccagta ttcatgatga tgaaagagcc tgttccataa gtattcttaa
      721 ccatacctgg ctcaaaagcc aactgtccaa agagggctgc ttgttggtcc ccagccatac
      781 ctgagattgg cacctctcca ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg
      841 agttagaacg aacttctgga agtatagcct tcggaatgtt aaggatttcc aaaatctcat
      901 catcccattt gagttcttta atgttataaa gcatggtacg agctgcattt gagtagtcag
      961 tcacgtgagc cgcaccgtca gtcaatttcc aaaccaacca agtatcgata gtaccaaaga
     1021 gcaattcccc tttttctgct cgctcttgag caccttctac atgatccaaa atccaacgaa
     1081 ccttggtagc agagaagtaa gcatcaataa tcaaaccagt cttttcatgg aatttttcca
     1141 cataaccttg gctttttagt tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga
     1201 tagcattgta gataggaagt cctgttttct tatcccagac aaccgttgtt tcacgttggt
     1261 tggtaatccc gattgcctcg atttgatttg gcttgacacc actttcgatg aaagcacccg
     1321 caataactga ctgaacagag ttccaaattt cattggcatt gtgctcaacc caacctgctt
     1381 gagggaaaat ctgggtaaac tctttttgac tcgagctaac cttttcccct tttttgttga
     1441 aaatgatggc acgagaactt gtagttccct ggtcaatggc catgatgtat ttttcttgtg
     1501 acatgtactg tcctcctgat aaagatcttg aggtgtttcc tctttacact tactagtata
     1561 caaaataaag cgctttcttg tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga
     1621 ttgtgtgaat ttcacaaaaa agacctggat taaccaagcc ttttaagtga ataataactg
     1681 acgaatccct gccaaatctt ccatatccaa gtcatttttt aaataataga ctggtgtctg
     1741 ttccttctta tgaatagggt tattggtaac cagcaaatca taatgccgac tagggtcata
     1801 agcttcaatg gtaataaaac gattgtattc caaataccgt ttcaaaatgg ctgccatcct
     1861 tgaaaagaca agaaaaccag atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt
     1921 ttcagccata tattcgatta actggagcca ttcccagaga atcttcttat ctaaatctgt
     1981 cccctgttga aaagcaggta gagcatgaaa aatctcctct gctgtctctt taaaatcatg
     2041 ttccatcagt aaatatggat gacgattctc taactggtac ttgtagcgat cctgtaaaat
     2101 atagccctta tagagataga cttgagcaca aagctgactg agttcatagg tgacatggtc
     2161 ctctgtataa tcccccaata gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa
     2221 atctgccaac tgccctccaa aaccaagaat atactccata gtatgaagag gaagaatgcg
     2281 atgagatagg agaaaagaga agaatatcat catctcacca tcctcaactc ctagtggaat
     2341 atgttgccca gcaaaaaagg acggaacctt tctcagcaaa cgaagataga agatattgtc
     2401 aaaataccct cgcattttct cttctataac ttgaaactga caagcattga cccgaagacg
     2461 ttgttgactg atgtgagccc agagaaccaa gtccaatttc tgccccgcag acaaacttgc
     2521 accgcagatt tcctctaaat tggcaatctc ctgttttctc tctggtttct gcatgtgacc
     2581 ttcccattcc tgactcgacc agacctttcg gaaaagacag aaatagaaat agcgaatctg
     2641 atgctctgga cctcgccaac gtccattttg gatggataaa tcaaattctg acaaaatctg
     2701 atttaaacca gccaagtgac gaccaagcgt agcctcgcta atcactaatt cttgagccag
     2761 ctgatgggct aaaaactgtt ggtggtagag aagataaacc aaaatctggt atttaacagc
     2821 actctccaaa aacaagctcc gaatatctct ccccttggta gctgcaccga tagacagacg
     2881 cagattttca tcttctgagt gaatagtcag ttctaagcca ctatccaaag ccttgtcatt
     2941 gagcagggtg acatatttgg ttagggttgc ttttgaaaat cctgtttctt ccattacagc
     3001 cttgacggtc gtctgagact cttgtaatag aaaggaaagg attgaaaatt gaccacactc
     3061 ggctttctcc atcaaatctc ctaaatacat ttgttatccc tttcattttc taccttaagc
     3121 atagcataaa tcttacaaat gctaaaataa tctgtttctc tttttatttt catgctgatt
     3181 tcctggtcca ttatcctgaa aatcagtaaa cacacggctc cccctttggg catttttatg
     3241 ctaaaatagt agctatggat aaaattatta aaactatatc agaaagcgga gcctttcgtg
     3301 cttttgtcct tgatagcact gaaaccgtcc gcactgctca agaaaaacat caaacccaag
     3361 ctagctcaac tgtagcgctt ggtcgaactc ttatcgccag ccagattctc gcagccaatg
     3421 aaaaaggaaa taccaaactt acagttaagg tgttgggatc tagctctcta ggtgctatta
     3481 tcaccgtcgc tgataccaag gggaacgtca aaggctatgt tcaaaatcct ggtgttgaca
     3541 tcaaaaagac tgcgactggt gaagtcctag tcggaccttt tgttggaaat ggtcaattcc
     3601 tcgttatcac agactacggt actggaaatc cttacaactc tataactccc ctcatctctg
     3661 gagaaatcgg tgaagacctt gccttttacc ttactgaaag ccaacaaacg ccttcagcgg
     3721 tcggcctcaa tgtccttttg gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag
     3781 ttcaagtctt gccaggagcc aagaaagaag agattgctcg ctttgaaaaa cgcatccaag
     3841 aaatgccagc tatctctact cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg
     3901 ctatctacgg ggacgaagcc tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg
     3961 actgtagcca tgaacgcttt atgaacgctc ttgccagcct tccaagctca gacttacagg
     4021 aaatgaaaga ggaagaccac ggtgcagaaa tcacttgtca attctgccaa actacttaca
     4081 actttgatga aaaggacctg gaggaactca ttcgtgacaa atcttaatac accttttatg
     4141 attggcaata ttgagattcc caatcgtacc gttttagcgc ctatggctgg cgtgaccaac
     4201 tcagcctttc gtaccatagc aaaagagctc ggagctggac tcgttgtaat ggaaatggtc
     4261 tctgacaagg gaatccaata caacaacgaa aaaaccctgc acatgcttca tatcgatgag
     4321 ggcgaaaacc ctgtctctat ccaacttttt ggtagcgatg aagacagcct agcacgcgca
     4381 gcagaattca tccaagaaaa caccaagacc gatatcgtcg atatcaacat gggctgccct
     4441 gtcaacaaaa tcgtgaagaa cgaagctggt gctatgtggc tcaaggatcc tgacaagatc
     4501 tactctatca tcaacaaggt ccagtctgtc cttgatatcc cacttactgt caaaatgcgt
     4561 accggctggg cggacccatc tcttgcagta gaaaatgccc tcgctgctga ggctgcaggt
     4621 gtttctgccc tcgccatgca tggccgtacc cgtgaacaaa tgtatactgg ccacgcggac
     4681 cttgagaccc tttacaaggt tgcccaagct ctaaccaaga ttccattcat cgccaacggt
     4741 gatatccgta ctgtccaaga agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc
     4801 atgattggcc gagctgccat gggaaatcct tacctcttca accaaatcaa ccattacttt
     4861 gaaacaggag aaatcctacc tgatttgaca tttgaagaca agatgaagat cgcctacgaa
     4921 cacttgaaac gattgattaa cctcaaagga gaaaacgtcg cagttcgtga attccgcggc
     4981 ctcgctcctc actatctccg tggaacatct ggcgctgcca aactccgtgg agccatttcg
     5041 caagctagca ccctagcaga gattgaagcc ctcttgcaat tggagaaggc ttaatagttt
     5101 aaaacccgta actctcttaa agagcctctt gaatgccgcc attctttcct catcaaaaaa
     5161 actccgtagt ctctagcgct ataaatccgg ctagagatta cagagttatt ttttaatcta
     5221 aacttcctac aagggtatat tatctactga aaggatatgg tatttgtagg gaatacttta
     5281 aagagttctt acaggaagtc agtattaact agttatatta ggtttagttt acccattcac
     5341 cattggcatt gactccatag ccatctacag ttgtgttgac tgcaagggca cctgagccat
     5401 tgacatagta ccatttatct gatactttga accattggct tgcttt
//
LOCUS       DAVBOU010000084         4996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBOU010000084 DAVBOU010000000
VERSION     DAVBOU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.085"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            298..1843
                     /locus_tag="VQ879_002049"
     rRNA            298..1843
                     /locus_tag="VQ879_002049"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1895..1967
                     /locus_tag="VQ879_002050"
     tRNA            1895..1967
                     /locus_tag="VQ879_002050"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1928..1930,aa:Ala,seq:tgc)
     gene            2092..4993
                     /locus_tag="VQ879_002051"
     rRNA            2092..4993
                     /locus_tag="VQ879_002051"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1408 a         1017 c         1468 g         1103 t
ORIGIN      
        1 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt
       61 ggaacacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      121 gcgaaagcgg ctgtgatata ctaatatagt tgtcgcttga gagaagcgag tgacaaagac
      181 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacataag ttgtagtact
      241 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagtgagaac tcaaactttt
      301 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta
      361 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag
      421 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt
      481 agatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt
      541 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag
      601 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta
      661 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt
      721 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact
      781 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt
      841 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt
      901 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc
      961 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac
     1021 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc
     1081 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc
     1141 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg
     1201 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta
     1261 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgacga ctctagagat
     1321 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt
     1381 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcatttag
     1441 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat
     1501 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc
     1561 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa
     1621 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
     1681 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
     1741 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta
     1801 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga taaggaactg
     1861 cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc ttagctcagc tgggagagcg
     1921 cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccattg gtgagagatc
     1981 accaagtaat gcacattgaa aattgaatat ctatatcaaa tagtaacaag aaaataaacc
     2041 gaaaacgctg tagtattaat aagagtttat gactgaaagg tcagaaaata aggttaagtt
     2101 aataagggcg cacggtggat gccttggcac taggagccga cgaaggacgt gacaaacgac
     2161 gatatgcctt gggtagctgt aagtaagcga tgatccatgg atttccgaat gggggaaccc
     2221 aacaggtaat acctgttacc cacatctgtt aaggatgtga ggaggaagac gcagtgaact
     2281 gaaacatcta agtagctgca ggaagagaaa gcaaaagcga ttgccttagt agcggcgagc
     2341 gaaacggcag aagggcaaac cgaagagttt actcttcggg gttgtaggac tgcaatgtgg
     2401 actcaaagat tatagaagaa tgatttggga agatcagcca aagagagtaa tagcctcgta
     2461 tttaaaatag tctttgtacc tagcagtatc ctgagtacgg cgggacacgt gaaatcccgt
     2521 cggaatctgg gaggaccatc tcccaaccct aaatactccc tagtgaccga tagtgaacca
     2581 gtaccgtgag ggaaaggtga aaagcacccc gggaggggag tgaaatagaa cctgaaaccg
     2641 tgtgcctaca acaagttcga gcccgttaat gggtgagagc gtgccttttg tagaatgaac
     2701 cggcgagtta cgttatgatg cgaggttaag ttgaagagac ggagccgtag ggaaaccgag
     2761 tctgaatagg gcgccttagt atcatgacgt agacccgaaa ccatgtgacc tacccatgag
     2821 caggttgaag gtgcggtaag acgcactgga ggaccgaacc agggcacgtt gaaaagtgct
     2881 tggatgactt gtgggtagcg gagaaattcc aaacgaactt ggagatagct ggttctctcc
     2941 gaaatagctt tagggctagc gtcgacatta gagattcttg gaggtagagc actgtttggg
     3001 tgaggggtcc atcccggatt accaatctca gataaactcc gaatgccaat gaattatggt
     3061 cggcagtcag actgcgagtg ctaagatccg tagtcgaaag ggaaacagcc cagaccacca
     3121 gctaaggtcc caaaataatt gttaagtgga aaaggatgtg gggttgcaca gacaactagg
     3181 atgttagctt agaagcagct attcattcaa agagtgcgta atagctcact agtcgagtga
     3241 ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg aagctgtgga tacctttata
     3301 ggtatggtag gagagcgttc tatgtgtgat gaaggtatac cgtgaggagt gctggaacgc
     3361 atagaagtga gaatgccggt atgagtagcg aaagacaggt gagaatcctg tccaccgtaa
     3421 gactaaggtt tccaggggaa ggctcgtccg ccctgggtta gtcgggacct aaggagagac
     3481 cgaaaggtgt atccgatgga caacaggttg atattcctgt actagagtat gtagtgatgg
     3541 agggacgcag taggctaact aaagcagacg attggaagag tctgtctaag cagtgaggtg
     3601 tgaattgagt caaatgctta attctataac attgagctgt gatggggagc gaagtttagt
     3661 agcgaagtta gtgacgtcac actgccaaga aaagcttcta gcgtttaaac atactctacc
     3721 cgtaccgcaa accgacacag gtagtcgagg cgagtagcct caggtgagcg agagaactct
     3781 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgct gactttaagt
     3841 cagccgcagt gaataggccc aagcaactgt ttatcaaaaa cacagctctc tgctaaatcg
     3901 taagatgatg tatagggggt gacgcctgcc cggtgctgga aggttaagag gagtgcttag
     3961 cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta
     4021 aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta atgatttggg
     4081 cactgtctca acgagagact cggtgaaatt ttagtacctg tgaagatgca ggttacccgc
     4141 gacaggacgg aaagacccca tggagcttta ctgcagtttg atattgagtg tctgtaccac
     4201 atgtacagga taggtaggag tctaagagat cgggacgcca gtttcgaagg agacgctgtt
     4261 gggatactac ccttgtgtta tggccactct aacccagata ggtgatccct atcggagaca
     4321 gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa
     4381 aggttccctc agaatggttg gaaatcattc gcagagtgta aaggtataag ggagcttgac
     4441 tgcgagagct acaactcgag cagggacgaa agtcgggctt agtgatccgg tggttccgta
     4501 tggaagggcc atcgctcaac ggataaaagc taccctgggg ataacaggct tatctccccc
     4561 aagagttcac atcgacgggg aggtttggca cctcgatgtc ggctcgtcgc atcctggggc
     4621 tgtagtcggt cccaagggtt gggctgttcg cccattaaag cggcacgcga gctgggttca
     4681 gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg taggaaattt gagaggatct
     4741 gctcctagta cgagaggacc agagtggact taccgctggt gtaccagttg tcttgccaaa
     4801 ggcatcgctg ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaaac
     4861 ccacctcaag atgagatttc ccatgattat atatcagtaa gagccctgag agatgatcag
     4921 gtagataggt tagaagtgga agtgtggcga cacatgtagc ggactaatac taatagctcg
     4981 aggacttatc caaagt
//
LOCUS       DAVBOU010000085         4768 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBOU010000085 DAVBOU010000000
VERSION     DAVBOU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4768
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.086"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..445
                     /locus_tag="VQ879_002052"
     CDS             <1..445
                     /locus_tag="VQ879_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3144138.1"
                     /translation="IALRKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNYSHDM
                     KLFKMSCRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTAEDKACNHALSKE
                     RSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(434..1081)
                     /locus_tag="VQ879_002053"
     CDS             complement(434..1081)
                     /locus_tag="VQ879_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3144139.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(1190..1708)
                     /locus_tag="VQ879_002054"
     CDS             complement(1190..1708)
                     /locus_tag="VQ879_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3144140.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1935..2804)
                     /gene="rsmI"
                     /locus_tag="VQ879_002055"
     CDS             complement(1935..2804)
                     /gene="rsmI"
                     /locus_tag="VQ879_002055"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3144141.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2807..3124)
                     /gene="yabA"
                     /locus_tag="VQ879_002056"
     CDS             complement(2807..3124)
                     /gene="yabA"
                     /locus_tag="VQ879_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3144142.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(3164..4054)
                     /locus_tag="VQ879_002057"
     CDS             complement(3164..4054)
                     /locus_tag="VQ879_002057"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3144143.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(4051..4689)
                     /locus_tag="VQ879_002058"
     CDS             complement(4051..4689)
                     /locus_tag="VQ879_002058"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3144144.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
BASE COUNT         1348 a         1068 c          788 g         1564 t
ORIGIN      
        1 aatcgcccta agaaaacaat tagcgaatca ttctggtaaa aagaaatttc acgctatgaa
       61 ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatcg ctgtgaacta
      121 tagtcatgat atgaagttgt tcaaaatgag ttgtagaaat atcggacaag ctggtaaaat
      181 cttggccgac agtggttatc aagggctcat gaagatatat cctcaagcac aaactccacg
      241 taaatccagc aaactcaagc cgctaacagc tgaagataaa gcctgtaacc atgcgctatc
      301 taaggagaga agcaaggttg agaacatctt tgccaaagta aaaacgttta aaatgttttc
      361 aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggtat
      421 tatcaatcat gaactaggat tctagttttg caggaagtct aatgtaattc tcaagctgtg
      481 agttcattat gatttgtaaa tccgatatat cttcagcagc taaaaacaca ttttgaaatg
      541 ttccaagtcc gttttcacca aaactatatt ctctcttact atacttactc ttattattct
      601 ctatatagtt agagtcaagg ttcttaacct cttgaagttc attttcttta cttctgaggt
      661 taaaatcttt tacttctgaa gttaagtttt ttgacttctg taagtcattt tcttttacct
      721 gaaatatact cataaagtct ttaacataaa tgatgttcgg cttaccaagt ccaagcctta
      781 ctctttcgat cagtcctatt ccttttttta catcaagctc atctaatgtt tttatggcag
      841 ttggctttga gatatttctt cttttcataa tttcttcgac agtaaaatag ataaatactc
      901 tgccttcctt gtctatccag ttattcttaa atgacattcc tgtctgttta agaagtatgg
      961 aataaaggat aattgcttct gctgataagc cccgaaattc ttctctatca actaatatct
     1021 ccggtacttt taagaagtta aatctttccg cttctctgtt ataaaaatat tcaaagtcca
     1081 tgcaagatca cctcccttct taaaaatttg caaagaaaaa gacgatagtt tttcttctat
     1141 cgcctttggt aaccattttt atgaaatttt ttaaagttaa aaatataatt tataatacta
     1201 tcttcttcca ttttctgatt ttagttctga aagttccaaa aggtgcaacc gtatttacat
     1261 gaataaactt atacacttcc caagtcgctg ttttagtcgc ttcatcagcc cactttctca
     1321 tatgcggttc aaataattct tcctcactca acgaatcaat cattgcagag atagaattaa
     1381 tattttcatt taattttgct ttcaactctt gcagagataa atgagcgtag gtatctgtga
     1441 accactgata taattcacca agttgattcc atttaaattt atccgatggt gtttttactt
     1501 gaagcccctt tctttcatct tcttcccatt taagaaccaa gttggtccaa ccaacctgat
     1561 aagcaaggtt ttctgctgga gttctgtcaa cttcatcagc tctcttatct tttaaatttt
     1621 ctggaatatt atcaaattct aaaatatatt tctcaaatgt tttctctatc tcagctttta
     1681 gttcttcttt attttcgtat gttcgcaaaa aatcaccttc tttctgattt atcaatcctt
     1741 tgatttaaaa tgaccttatt tttctattta taccttctaa gaacgctata actgctgctc
     1801 caaccatcgg tattccgtat gggcttaata aaaaacttaa taccaaagct tctataccaa
     1861 gtgatacatc tttatattac catcactaat taagttaaac agaaacagac agaattatta
     1921 cattctgtct ccctttattg tttttcttcc caatcgtggt aggcagcgta gagttgactc
     1981 ttattccact ggtaaatctt agctacttcc ttaatagctt gatttttctt catgccttgc
     2041 tggatacggg cttggatttc taagaacaag tcctcctcgt ctttttcctc cacatcctga
     2101 ctggcacctt caacaataag aaggcattcg cccttgagtg gcgtttcagc gatgctttcc
     2161 agcaattcag aaatggtacc tctttggtat tcttcataga ttttagtcaa ttccctgacc
     2221 aagactaccg agcggtcacc gtagacttct agcatatttt ccaatgtatc tgccacacga
     2281 tgggacgatt cataaaaaat ctgagtttca ggatagtctt ttttcgagtc gaaaaattgc
     2341 ttttgctgac ctgattttct cggtaaaaag ccgtaaaaga tatgtggctg cggcgctaaa
     2401 ccactggcaa tcaaggcaga aattcctgca gaggcacctg gaacagtcac aactgcaatt
     2461 tcttcctcaa tagctgcctt aaccaaatca tgaccagggt ctgaaatgct aggcaaaccg
     2521 gcatcagaga cctgagcaat actttgccct gctttcaaga aaccaatcaa atcaggaatt
     2581 ttttccttgg cattgtgctc atgaaaactg atctgcttgg tggaaatgtc aaaatgcttg
     2641 agcaaaagac ctgtattgcg cgtatcctca gcagcaatcc agtccacttc tttcaaggtc
     2701 tggatagcgc gaaaagtcat atcatctaga ttgccaatcg gcgttgccac tagatacagc
     2761 ttgccatagg gagactgccc cttaaaactt ttttgaattt gcatgcctac tccctgtata
     2821 acaactcatc acagaacata cattcttcgt cctgctctcg acgttgtcca taaaaatcat
     2881 tacatacgtg aaatccatca cggtaaatac gacggacact ttcgcgaaca tgcttggcct
     2941 tgacgggagc gtctgcttcc acctcaccca agcgttctcg caacttacta ttttccaagc
     3001 gaagagctgt attttcctct accaggctct tgagattttt cttgatggct tccacatcgg
     3061 ccaaggttac caataattgt tgggaaaaat catccagcgc gtcaaataat tcttttttgt
     3121 ccataaaaca gctctttcct ttctttatca ttcatttttg agtttatatt tctttcaaga
     3181 ccagatattc catggcattt tgaaagctga cattagcttg ccacattttt ctagcttcta
     3241 gtaaatcttg tagaatcact cttactctta cctgcaagag gtcctgccca cagagaactt
     3301 caagaatccg taaaacctga tcctgttttt ccttatcatc tgccaagttg gctaatttgg
     3361 caacctgtag ataactttct tttttcttag ctactaacca agtcagcagg cgttcacttt
     3421 catcgaccaa ggtccaaaaa cttgcctgat tagccaactt ttctgcttca gctcgcgatt
     3481 gactaaactt agctaaaaga gtcgcttttt tcttaacaag tcccatttgt tctaagagta
     3541 agataagttt ttcttcttgc tttttaaagt ggaagatctg ggtccgactt cggattgtcg
     3601 gtaacatctt ttcctcatcg ctagtcaaga agaaaatata aacttcactc tggggttctt
     3661 cgatgacctt gagcagagaa ttggctgcgt tgggatgcat tttatccgct tgctcgatga
     3721 taaagacctg ttgctggctt tcaatccctg cttgagaaaa ctgtcccacc aattccctaa
     3781 tgcgttctgt cttgatgacc tgattgactg gcttaatcaa ggtgacatcg ggaaattctc
     3841 cctgttcaat cagcttgcaa cttcggcatt tctcacatgg taagacgcca actttatccg
     3901 tacaaaagag gctcttagct aaaaattgcg ctatttccaa gcttccaaag aaacctgaaa
     3961 agagataggc gtgattgagc tggtcttgtt ctaagatacg gacaaaacgg tcaaactgag
     4021 ctggttgcca agcctttagt tgatcttgtt tcatttggcc aagcccattc cgtcaaacaa
     4081 gacagccttg gtagtttcca caacttgctc caaagggaga ctagcatcaa tcttgacaat
     4141 gcgatttccc tctttatcca gaagagaaag gtagccttga cgaacttttt tatgcaagtc
     4201 caacccttcc aaatccaaac gattaacctc gcggtcacta ttagcagcaa tacgagccag
     4261 cccttcttcc acctcgatgt caaaatagag tgtcaaatcg ggtttgaggc catctgtcgc
     4321 aaactgattg agccagtcaa tggcttcaat atctaagcca cgaccaaatc cctgataggc
     4381 aacagaacta tcgataaaac gatccatgat gaccaacttg ccagcttcaa gggctggaag
     4441 aactttttcc accaaatgct gtctgcgact ggcaatatag agaagtagct ctgttttagc
     4501 atccatctga gtatgacttg gatccaaaat cacttcccga atcttctccc caatcaagac
     4561 tccgccaggt tcacgggtcg tcagcacctt tactcctttt tcctctaaaa ttggtagcag
     4621 agcctctaaa acactggtct tgcctgctcc ctctggtccc tcaagagaga ctaaaaatcc
     4681 ttttgacatg tctaactcat ttctttttta ctacttctat tctatcaaaa aaataggggt
     4741 ttgtgacaat ctttttgtct tctcattt
//
LOCUS       DAVBOU010000086         4653 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBOU010000086 DAVBOU010000000
VERSION     DAVBOU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.087"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(80..517)
                     /locus_tag="VQ879_002059"
     CDS             complement(80..517)
                     /locus_tag="VQ879_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3144145.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ879_002060"
     CDS             complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ879_002060"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3144146.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDRLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3491..3841
                     /locus_tag="VQ879_002061"
     CDS             3491..3841
                     /locus_tag="VQ879_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3144147.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4056..4160
                     /locus_tag="VQ879_002062"
     CDS             4056..4160
                     /locus_tag="VQ879_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3144148.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4165..4398
                     /locus_tag="VQ879_002063"
     CDS             4165..4398
                     /locus_tag="VQ879_002063"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144149.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
     gene            4525..>4653
                     /locus_tag="VQ879_002064"
     CDS             4525..>4653
                     /locus_tag="VQ879_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET3144150.1"
                     /translation="MEQLHFITKLLDIKDPNVQILNIINKDTHKEIIAKLDYDAPSC"
BASE COUNT         1424 a         1112 c          856 g         1261 t
ORIGIN      
        1 gcccgcggct agtttcctag tttgctcttt gattttcatt gagtataaca caaaaggtag
       61 cccatcagct acctttttct tatgcttcct caatcaagcg agtatgttct ctcttgatac
      121 agcgattcat cacgatatca tcacatccac catcacgcaa aatctctttc gcttttaaac
      181 tttcaagtcc tagctgtgcc caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca
      241 catcgggcag aaattcactg cgacgataaa cattgacaat atctacagga aaaggaattt
      301 cagcgaggct agcataagcc ttttcaccca agatttcgcc acctgccgcc ttgggattga
      361 ctgggatgat tttatagccc cgagcctgca tttcctttgt cactcgattg ctggttgttt
      421 cttcacggtc agacaaaccc accacagcaa gggttttact cgttgcgaga tactgacgaa
      481 tcacgccatc acttggattg ataaattctt gactcataga aaacctcctt tttcatcagt
      541 atagcacatt ttgaaaaggt ttgcagaatt ctactacaaa aaaggaggac tagccccctt
      601 tttatttagc ctcgtaccag gttgcccctt cattctcatc tgcgataaga ggaacactga
      661 gttgaatggc ttcttccatg gtttgtttca ccaatttttt catctctacc aattcagatt
      721 taggcacttc aaggacgatt tcatcgtgca cttgtaacag catcttagtc tgataaccac
      781 ctgcaaccaa ggctttatcc agctgaatca tggcaatctt gagaatatct gctgccgaac
      841 cctggatagg tgagttgata gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg
      901 aattgatatc tggcaactca cggcgacgct taaagagggt ctctacatag cccttatcac
      961 gcgcctcccg caccacttca tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg
     1021 tatcaatgta ggctttggct tccttacgac taattcccaa attattagac aagccaaagt
     1081 ctgaaatccc ataaaccact ccaaagttaa ctgccttggc attgcgacga tcatttgcag
     1141 tcacattatc aggacgctca atgccaaaga cccgcatggc tgtcgaagta tggatatctg
     1201 ccccctcttg gaaggcctta atcaagtgct catccttaga aatatgcgcc aaaacgcgca
     1261 attcaatctg tgaatagtca gagctgagta gcacactatc ctcccactct ggcacaaaag
     1321 ccttccgaat caagcgccct tgttccaatc gggcaggaat attttgcaag tttggatcca
     1381 cactagacaa acgcccggtc tgggtcaaat cctgcatata gcgagtatga atctttccat
     1441 cagccaaaat ccagtcctgc aagccaatta cataagtaga ttgaatctta gcaatttgac
     1501 ggtaatccag gattttctta acaatcggag caataggagc gagacgctcc aacacatcca
     1561 ctgctgtcga ataacctgtc ttggttttct tagtgtattc tagaggaagt cccaatttct
     1621 caaagagaag cacgcccaac tgcttaggcg agttgacatt aaactcctca ccagccagct
     1681 cgtaaatctc ttgagtcagt ttttcaatga caagctcatt ttcagcctgc atctcaagca
     1741 aggtctcttt cttgaccata atcccagcaa tttccatctt ggcaaggaca aaagccagag
     1801 gttgctccat atcataaaga agctctaatt gcccattttc gctgagtttt tcaagtaaaa
     1861 taggctctgt ttctaccaaa acagcaagtt tacaagctaa gtgttccaag aatttctcac
     1921 gttcaggaat ggccttttta acacccttac cgtagaaagt ttcatcatca accaagtaag
     1981 tctgaccata aagactagcg atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt
     2041 atttagccaa acggatgtca aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa
     2101 gaactttaac cttcttaaag tcataaactc tcagagatgt tttttctaag aaatccttga
     2161 aaatcgggtc ttgcaacagc tcaagcttgt ctgtggcata gagcctatcc ccacaagacc
     2221 aggcaaatcc aaccaaatta tccgtatggt aattctcacc aaaaagctca aagtggaaga
     2281 tagactcttc actcagcata tcttgactga tttggtcaac aatagtaaaa tccaaactct
     2341 cagacacatc agctgacgac acatttaaag cctgctttag ctgtttgaag cccatctcat
     2401 cgtagaattt cccaagattt tcaacatctg gaccactata gaccaagtcc tctaaaccaa
     2461 tcgcaatcgg tgccttggta tcaatggtcg ctagtgtttt agataaaaag gcctgttcct
     2521 tgtcattgat gagattttcc ttcatcttag aagtcttcat tccatcaata ttttcataaa
     2581 tcccctcaag cgaaccatgc tccagcaaga gcttaatacc cgtcttttca ccgactttgg
     2641 tcaccccagg gatattatcc gacttatcac ccatgagcgc cttgagatcg ataaactgag
     2701 ctggtgtgag gcccatttct tccatgaggt aatctggcgt aaaggcctca aactcagcca
     2761 cacctttctt ggaaatttca accaccgtat gctcatccgt cagctgaatc aaatccttgt
     2821 ccccactgac aatggtaata tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa
     2881 tgatgtcatc cgcctcatac tgagccagct catagtgacg aatccccata tgatccagca
     2941 actcacgaat gaaaggaaat tgctcacgaa actcatcagg agtcttggcc cgaccaccct
     3001 tatagtccgc atacatctct gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa
     3061 tatgactcgg ctcaacccgc tccaacaaat gactcaacat caactgaaaa ccataaatcg
     3121 cattggtatg caaaccagcc gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa
     3181 acgcccgaaa agctacagaa gacccatcaa tcaataataa ttttttctta tccatacacc
     3241 cattataaag gaaagaatca aaaaatacca ttgggaagag ctagagcaag tatttttcaa
     3301 actttttccg aataaataga tagagccaga gaatttagta aacctagatt taaaaatgtg
     3361 ctataatata gtatattgaa tctataatag tacaccttga ctgctaaaat atttctataa
     3421 attaatttga ctttcctgat agagttattc acatcttatt tcaactcact atagaaggag
     3481 gaataggagg attctcagac atccgggcat cagcccaact aatgatttga ttgctaagaa
     3541 aatattcagc aatccagaaa tcacttgtca atttattcgc gatatgctgg acttgccagc
     3601 aaaaaatgtg accattttgg agggaagcga tattcacgta ttactctcca tgccttactc
     3661 ggtgcaggat ttttatacca gtatagacgt cttggcggag ttggataacg gtactcaagt
     3721 aattattgag attcaagtcc atcatcagaa ttttttcatc aatcacttgt gggcttacct
     3781 gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag cgagaaggtg atactcacta
     3841 gatctacaaa cacatcgctc ctgtttacgt cattgctatc gtggatagta attatttctc
     3901 agatgacctg gcttttcata gctttagtat gcgcgaagac acaacaggtg aggtattggc
     3961 gattaccaac aatggacagg aaaaccatct ggttaagatg gcattcttgg aattaaaaaa
     4021 tacagagaaa ccagcaaaga caaggttcgc aagccatggt tggagttttt cggcaacaag
     4081 ccctttaccc agcaaccgca acgagccatt acccaagcaa atcaactgct ggactacaag
     4141 agctggtccg aggaggatag gaaaatgttt agtcaactac gtatgcgaga agaacaagcc
     4201 ttgttagcgc aggactatgc cttggaaact gctagggcgg gaggtattga acaaggctta
     4261 gagcgtggga aagttgaagg aagggaagaa aggaaacttt ttgccttcct agacatagta
     4321 cgccaagatc ttctgacttc tgaggttgcc agccagcaat taggtatgtc agtatctgaa
     4381 tttgaggcac tgttgtaaaa tggctccata atatccatag tgggtaaatc ccctatggat
     4441 attatggagc ctattttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca
     4501 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
     4561 attaaagacc ctaatgtcca gattttaaac atcatcaata aggatacaca caaggaaatc
     4621 atcgccaaac tggactacga cgccccatct tgc
//
LOCUS       DAVBOU010000087         4615 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBOU010000087 DAVBOU010000000
VERSION     DAVBOU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.088"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..279
                     /locus_tag="VQ879_002065"
     CDS             <1..279
                     /locus_tag="VQ879_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3144151.1"
                     /translation="NGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTW
                     YYLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            680..1801
                     /gene="mnmA"
                     /locus_tag="VQ879_002066"
     CDS             680..1801
                     /gene="mnmA"
                     /locus_tag="VQ879_002066"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3144152.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1942..2397
                     /locus_tag="VQ879_002067"
     CDS             1942..2397
                     /locus_tag="VQ879_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3144153.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2407..4320
                     /gene="mnmG"
                     /locus_tag="VQ879_002068"
     CDS             2407..4320
                     /gene="mnmG"
                     /locus_tag="VQ879_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3144154.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1339 a          934 c         1127 g         1215 t
ORIGIN      
        1 aacggttcat ggtactacct aaacgctaac ggtgctatgg caacaggttg ggctaaagtc
       61 aacggttcat ggtactacct caacgctaac ggttcaatgg caacaggttg ggtgaaagat
      121 ggagatacct ggtactatct tgaagcatca ggtgctatga aagcaagcca atggttcaaa
      181 gtatcagata aatggtacta tgtcaatggc ttaggtgccc ttgcagtcaa cacaactgta
      241 gatggctatg aagtcaatgc caatggtgaa tgggtttaag ccgattaaat taaatcatgt
      301 taagaacatt tgacatttta attttgaaac aaagataagg ttcgattgaa taaatttatg
      361 ttcgtattct ttaggtacct atcttatgat ttcaggaaat gtcattaaaa aaacgactcc
      421 ttttctctaa cttgaaaaat agattagaga aaatgggttg ttttatttat tatagttatt
      481 tgaatgaaga taagaagaag gtatactcac atcattcaca taatctgtat attgactata
      541 agttttaaaa aacaattttt aagctcttcc ttgtcttctc taaccaagcg tgttataatg
      601 aatactgctc aagcgacctt caatcgtgaa gcacacacga ccttcaatcg tgaataaacg
      661 aatagatggg agacttacca tgagtgataa ctctaaaaca cgtgttgtcg tggggatgag
      721 tggtggtgtt gattcgtcgg tgacggctct tttgctcaag gagcagggct acgatgtgat
      781 cggtatcttc atgaagaact gggatgacac agatgaaaac ggcgtctgta cggcgaccga
      841 agattacaag gatgtggttg cggtggcaga ccagattggc attccctact actctgtcaa
      901 ttttgaaaaa gagtactggg accgcgtttt tgagtatttc ctagcggaat accgtgcagg
      961 gcgcacgcca aatccggacg ttatgtgcaa caaggaaatc aagttcaagg cctttttgga
     1021 ctatgccatg accttggggg cagactatgt agcgactggg cattatgctc gagtggcgcg
     1081 tgatgaggac ggcactgttc acatgcttcg tggcgtggac aatggcaagg accagaccta
     1141 tttcctcagc caactttcgc aagaacaact tcaaaaaacc atgttcccac taggacattt
     1201 ggaaaagcct gaagttcgaa aactagcaga agaagcaggc ctttcgactg ctaagaagaa
     1261 agactcgaca gggatttgct ttatcggaga aaagaacttt aaaaacttcc tcagcaacta
     1321 cctgccagct cagcctggtc gcatgatgac tgtggatggt cgcgatatgg gcgagcatgc
     1381 aggtctgatg tattatacaa tcggtcagcg tggcggactc ggtatcggtg ggcaacacgg
     1441 cggtgacaat gccccttggt tcgttgtcgg aaaagatcta agcaagaata ttctctatgt
     1501 aggacaagga ttctaccatg attcgctcat gtcaactagc ctagaagcca gtcaagtcca
     1561 ctttactcgt gaaatgccag aagagtttac gctagaatgt acggctaaat tccgttaccg
     1621 tcagcctgac tctaaggtga ccgtccatgt caaaggagac aaggcagagg tcatctttgc
     1681 ggaaccacaa cgcgcgatta caccaggcca ggcagttgtc ttttacgatg gcgaagagtg
     1741 tctaggtggt ggtttgattg acaatgctta ccgcgatgga caagtttgtc agtacattta
     1801 gattgacaaa ttttctcaat ttgctacaat aataacagca atagaaatga tggtcaaagc
     1861 tcatggatgt tgcaggcttt tttgtcctgc acttctttgg agttttgact gtttttgtgt
     1921 cgtttaaggg aaaggacaag aatgactcaa caagactttc ggacaaaagt agacaatacg
     1981 gtttttggtg ttcgggcgac agctttgatt cttcaaaatc acaagcttct agtcaccaaa
     2041 gacaagggca agtattacac tatcggcggt gcgattcaag tcaatgaaag cacggaagac
     2101 gcggtagtcc gtgaagtgaa ggaagaactg ggtgtcaaag ctcaagctgg gcagctagct
     2161 tttgtggttg aaaatcgttt tgaacaggac ggtgtttcct atcacaatat cgagtttcat
     2221 tatctggtgg acttacttga ggatgcccca ttgaccatgc aggaagatga gaaaaggcag
     2281 ccctgtgagt ggattgactt ggataagctt gaggatatcc agctagttcc agccttttta
     2341 aaaacggccc taccagattg ggaaggccaa ctaagacaca ttcatcttga ggaataggag
     2401 agaaacatga cttatcattt tactgaagaa tacgatatta ttgtaattgg tgcgggacac
     2461 gctggggttg aggcttcctt ggccgctagc cgtatgggct gtaaggtcct gcttgcgacc
     2521 atcaatattg aaatgctggc tttcatgcct tgtaatccct ctatcggtgg ttctgctaag
     2581 gggattgtcg tacgtgaagt cgatgccctc ggtggcgaga tggccaagac cattgacaag
     2641 acttacatcc agatgaagat gctcaacaca gggaagggcc cagccgttcg tgcccttcgt
     2701 gcgcaggctg ataaggaact ttactctaag gaaatgcgca agacagttga aaatcaagaa
     2761 aatctgaccc ttcgtcaaac catgattgat gagattttgg tggaagatgg caaggttgtc
     2821 ggtgtgcgta cagccaccca tcaagaatat gctgctaagg ctgttattgt gacgacaggg
     2881 actgctctcc gtggggaaat tatcatcgga gacctcaagt actcatcagg tcctaaccac
     2941 agcttggctt ctattaacct agctgacaat ctcaaggaac tgggtctcga aatcggtcgt
     3001 ttcaagacag gaacccctcc acgtgtcaag gcttcttcta tcaattacga tgtgacggaa
     3061 attcagccag gagacgaagt gcctaatcat ttctcataca cttcacgtga tgaggattat
     3121 gtcaaagatc aagtgccatg ctggttgacc tataccaatg gtaccagtca tgagattatc
     3181 caaaacaacc tccaccgtgc gcctatgttt acaggtgtgg tcaagggagt ggggcctcgt
     3241 tactgtccgt cgattgaaga caagattgtg cgctttgcgg acaaggaacg tcaccaactc
     3301 ttccttgagc cagaagggcg caatactgag gaagtctatg ttcaaggact ttcaaccagt
     3361 ctgcctgagg atgtccagcg tgacttggtt cattccatca aaggtttgga aaatgcagag
     3421 atgatgcgga caggttatgc tattgagtat gatatggtct tgcctcatca gttgcgtgcg
     3481 actttggaaa ccaagaaaat ctcaggtctc ttcactgctg gtcagacaaa tggaacatca
     3541 ggttatgaag aagctgctgg ccaagggatt atcgcgggta tcaatgcggc tctgaaaatc
     3601 caaggtaaac ctgagttgat tctaaaacga agtgacggtt atatcggggt gatgatcgac
     3661 gacttggtga ccaagggaac cattgaacct taccgtctct tgaccagtcg tgctgaatac
     3721 cgtctcattc ttcgtcatga caatgctgat atgcgcttga ctgagatggg acgcgagatt
     3781 ggccttgtgg atgatgaacg ctgggctcgt tttgaaatca agaaaaatca atttgataat
     3841 gagatgaaac gcctagacag tatcaaactc aagccagtca aggaaaccaa tgctaaggtt
     3901 gaggaaatgg gcttcaagcc gttgacagat gcggtgacag ccaaagaatt ccttcgccgt
     3961 ccagaagttt cttaccaaga tgtggtggcc ttcatcggac cagctgcaga agacttggat
     4021 gacaagatta tcgaattgat tgaaacagaa atcaagtacg aaggctatat ttcaaaagcc
     4081 atggatcagg ttgccaagat gaaacgtatg gaagaaaaac gcattccagc caatattgac
     4141 tgggatgaca tcgattctat tgcgacggaa gctcgtcaga agttcaaact catcaatcca
     4201 gaaaccatcg gccaagccag ccgtatttcg ggagtaaacc cagcagatat ttctattttg
     4261 atggtgtatc tggaaggtaa aaatcgtagt atttctaaaa ctcttcaaaa atcaaaatga
     4321 tacgtcgtcg gcttcttacg aatgagttca aagcttggct ttgattcatc tccagcctcc
     4381 catagttccc cgaactatgg gagctaactc aagttatgca ttttcctagc cttctggtct
     4441 gattttcatt gagttttaat ctcaaaagaa agcatagaga aaaacagctc cgaagacgga
     4501 gctgttttgt tgacttgtac tcaatgaaaa tcaaagagca aactaggaag ctagccgtag
     4561 gttgctcaaa gcactgcttt gaggttgtag atagaactga cgaagtcagc tcaaa
//
LOCUS       DAVBOU010000088         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBOU010000088 DAVBOU010000000
VERSION     DAVBOU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.089"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ879_002069"
     CDS             complement(60..659)
                     /locus_tag="VQ879_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3144155.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ879_002070"
     CDS             complement(661..1758)
                     /locus_tag="VQ879_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3144156.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ879_002071"
     CDS             complement(1758..2495)
                     /locus_tag="VQ879_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3144157.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ879_002072"
     CDS             complement(2497..3381)
                     /locus_tag="VQ879_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3144158.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ879_002073"
     CDS             complement(3368..3562)
                     /locus_tag="VQ879_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144159.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ879_002074"
     CDS             complement(3559..3765)
                     /locus_tag="VQ879_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144160.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          963 c          701 g         1262 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctccttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBOU010000089         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBOU010000089 DAVBOU010000000
VERSION     DAVBOU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.090"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ879_002075"
     CDS             720..1712
                     /locus_tag="VQ879_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3144161.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ879_002076"
     CDS             1714..2532
                     /locus_tag="VQ879_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3144162.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ879_002077"
     CDS             2534..3319
                     /locus_tag="VQ879_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3144163.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ879_002078"
     CDS             3358..3636
                     /locus_tag="VQ879_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3144164.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ879_002079"
     CDS             3621..3818
                     /locus_tag="VQ879_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3144165.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBOU010000090         3775 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBOU010000090 DAVBOU010000000
VERSION     DAVBOU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.091"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..154)
                     /locus_tag="VQ879_002080"
     CDS             complement(<1..154)
                     /locus_tag="VQ879_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3144166.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQISRNTIYGWLKLKEK
                     TGELNHQ"
     gene            complement(339..950)
                     /gene="rpsD"
                     /locus_tag="VQ879_002081"
     CDS             complement(339..950)
                     /gene="rpsD"
                     /locus_tag="VQ879_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3144167.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1145..2197)
                     /locus_tag="VQ879_002082"
     CDS             complement(1145..2197)
                     /locus_tag="VQ879_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3144168.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2194..2892)
                     /locus_tag="VQ879_002083"
     CDS             complement(2194..2892)
                     /locus_tag="VQ879_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3144169.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(3059..>3775)
                     /locus_tag="VQ879_002084"
     CDS             complement(3059..>3775)
                     /locus_tag="VQ879_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET3144170.1"
                     /translation="PAAYLEKAKGEGPFTAGVNHVIPYELFAGDGMLTRLLLKASDKA
                     PWSDNGDAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRANGTQTYSA
                     TVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHAT
                     GTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGLL
                     GLALAGLLGGLGLKNKKEEN"
BASE COUNT         1022 a          845 c          742 g         1166 t
ORIGIN      
        1 cttggtggtt tagctctcct gttttctctt ttagctttaa ccagccataa atggtattac
       61 gtgagatttg gaaaacgtgt gatgcttctg ttatactacc tgttcgctca caataagaga
      121 gaactttttt acgaaaatct attgaatatg ccataaaaga ttataccaca ttgtgtacta
      181 tttttggttc attttactat atcactttgg actatatcgg tctagttatg tctcaacgat
      241 tatagctgga tactaagaga aatcaaaaaa gcactaaggg agaacgtccc aaagtgctta
      301 atatcaaggc ctcaaagcct gtcttattca ataaaatatt acaacatctt gttgtagaat
      361 tcaacgacaa gtgcttcgtt gatttctggg ttgatttcgt cgcgttctgg caagcgagtc
      421 aatgaacctt ccaacttttc agcgtcgaat gatacgaatg ctggacgtcc aagagtagct
      481 tctactgctt caaggattgc tggaactttc aatgattttt cacgaactga gatcacttga
      541 cctggagtta cgcggtatga tgggatatca acgcgtttcc cgtcaacaag gatgtgaccg
      601 tggtttacga attgacgagc ttgacgacga gtagtcgcga gaccaagacg gtaaacaaca
      661 ttatccaaac gacgttccaa aagaagcata aagttgaaac ctaggattcc acctttgatt
      721 tttgtagctt gtacgaacaa gttacggaat tgtttttcac ctacaccgta agtgaaacga
      781 agtttttgtt tttcagccaa ttgcaaaccg tattctgaca atttagaacg gttgtttggt
      841 ccgtgttgtc ctggtacgta gttacgacgt gccaattctt tacctgtacc tgtaagtgaa
      901 aggccaaggc gacgagcttg tttccaagat ggtcctgtat aacgtgacat atgaatgtcc
      961 tcctgatata aataatattt cggtggaaat agtcacttag aaagccctga ttcgtgcaga
     1021 tgcccttcgc ctaaacagcc aaggttactt atcataagac acctgttgac gagcttcatg
     1081 ctttcctgct gatatttcac acaaaatcca ttctaccatg aatagctgga tttgtaaagg
     1141 ggttttaggc tttattttca ctaccagaga ggttgagaac gagggtaaag gtacttccta
     1201 gaccgtactg gctgctgact gtgatttccc cacccaattg atgggccaat tcacgcgcaa
     1261 tcgcaagtcc taatccatga ccacctgtct tcatgttacg cgaagtttcg acacgataaa
     1321 ggcgtttgaa aatattttcc aaatcctctg gggcaatgcc ctgcccttca tcggtcacac
     1381 tgattgaaag ctggtccttc tccagcttag ccaccacttc cagcttggtt cctggagcag
     1441 aatatttaaa agcgttatcg accagattca ccaagatacg agaaagctta gcataatctc
     1501 cctcaatccg ggcagactct gggattacct gcaagtggac atctcttctc tcctgctcaa
     1561 tcaaaaactg aaattcactc atgcactcaa ttaagagctt gtccagaaaa atactgtctt
     1621 tactggtagt ttccacctga tttctagctg tgtttagggt caaaaaattc aactcctcaa
     1681 ccagtttatt gagcctctcc gtctggcgtc caatggttgc tagataatga gcttgctccg
     1741 actccttgat aatcccatcc aaaatccctt ctaccgtcgc ttggatcgaa gtgataggag
     1801 tcttaatatc atgcgacaac tgagcaatca tcaagccctt ttctcgttcg ctttcttcca
     1861 aggaatcaaa gcttacctgc aaatcatggg acatctcatt aaaagtttgc cctaattgct
     1921 gaaattctac aggaccttga acctccaaat ttgaaggaaa atccttggcc gctacccgct
     1981 tggcatgctc cttgagtttg cccaacgacg taaagactgg caataggaga aagagactaa
     2041 tcccagcacc gacaaggctg gcaacgatgg tcatcccaag caaaaagtaa atctcgcctt
     2101 tcgcaatcag cattttttga acagcccaaa aaacaaccaa aatggttaag agggttgaaa
     2161 taatatatcc aaccaaaata taacttttta gtttcatgtt tgtcctctcg gtttctctat
     2221 cttatatccc aacccccaaa ctgtcttaat agtgggcgtt tggtcactac tatattttgc
     2281 cagctcctgt cgaagagcat ggatatgcac attcaaggta ttggtgtcat ccacgtagtc
     2341 ttctttccag atcttttcat agaggtctgt cttggagaaa actcgctctg gattgctagc
     2401 taaaatccac agcaattcaa atgatttaac agttaaatcc agcatttctt ctcctatttg
     2461 aacttcatga ctactatgat tcatttttag attgccaagg gaaatcagct ctgtttcgcc
     2521 cccacgatga aggcggcgca aaatattgtg gacacgcaaa accagttcac gtgggctaaa
     2581 aggcttagca ataaaatcat ctgctcccaa gctcaggccg taaatcttgt cctgttcact
     2641 ggtcttagca gtaataaata ggaaaggctg ctctggtgat aagtattgaa cctcactgat
     2701 taaatcataa ccatccatcc gaggcatcat gacatctgtg ataatcaaat caatcggttt
     2761 tttcttgaac agctctagcg cttccagtcc atcatgggct accaagacct gataacctgc
     2821 ctgaattaag tatctctgat gaatatctgt gatttctacc tcgtcgtcaa cgagtaaaat
     2881 tgtctttccc atctgtctct cctttgataa aaacagtgct atactgcttt aagtataaca
     2941 ctatttttat tgttttacga tgattttaat ctgctattga aagaaagtcc tgattgctga
     3001 ttgagttgtt aaactaatct tagtcagccc actatccatc atttatttcc ttagctgatt
     3061 agttttcttc ttttttgttt ttcaaaccta gaccaccgag taaacctgca agcgcaagcc
     3121 caagtaaacc aatacttgcc attgatgttt gagtctcacc agtatttggt agcatagctt
     3181 tatcctctga catcatcgta tcagacatct tgttagcaga agcagccatg ttttcacctg
     3241 ccatcgtgtt ggtagaactt gtcatggtgt cagcaggcat gctatctgta gtacctgtag
     3301 catgattgtg attcatcgga gtcacgccag aaccagagtt agaaggtgat aatgaaccat
     3361 ttgctgtgtc tgatgtttct ttaacattta tcttaatagt gactttttta gttgctacga
     3421 tgttgtccaa gtctggttta ccgtctttgt taccatagac attgactgta gcgctgtaag
     3481 tttgagtgcc gtttgctcgg aactggtcaa tgagcgcttg tttttctttg ccagctacat
     3541 ttccgtccaa ggctacttga tagaagtatt gacctttggt cttcacgttt tcgcctagtg
     3601 gagatagggc tgggttttta gcgtcgccgt tatctgacca tggtgccttg tcagatgcct
     3661 tgagcaagag acgagtcaac ataccatcac ctgcgaagag ttcgtatgga atcacatggt
     3721 tgacacctgc tgtgaatgga ccttcaccct tggccttttc taggtaggct gctgg
//
LOCUS       DAVBOU010000091         2987 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBOU010000091 DAVBOU010000000
VERSION     DAVBOU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.092"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            108..824
                     /locus_tag="VQ879_002085"
     CDS             108..824
                     /locus_tag="VQ879_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3144171.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1133..1558
                     /gene="rplK"
                     /locus_tag="VQ879_002086"
     CDS             1133..1558
                     /gene="rplK"
                     /locus_tag="VQ879_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3144172.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1766..2455
                     /gene="rplA"
                     /locus_tag="VQ879_002087"
     CDS             1766..2455
                     /gene="rplA"
                     /locus_tag="VQ879_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3144173.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          995 a          559 c          668 g          765 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctattaaaag attagtcaaa
       61 cgtttatcat cagaagtaga taaactatta gaaataaagg agtagaaatg aagaaaagat
      121 accttgtcgt gacagccttg ctagccttga gtctagcagc ttgttcacaa gaaaaagcaa
      181 aaaatgaaga tggcacagct aagacagaac agacagccaa agctgatggg acagtcggca
      241 gtaagtctca aggggctgcc cagaaaaaag cagaagtggt caataaaggt gattactaca
      301 gcatccaagg aaaatacgac gaaatcatcg tagccaataa acattatcct ttgtcgaaag
      361 actataatcc gggggaaaat ccaacagcca aggctgagtt ggtcaaactc atcaaagcga
      421 tgcaagaggc aggtttccct attagtgatc attacagtgg ttttagaagt tatgaaactc
      481 agaccaagct ctatcaagat tatgtcaacc aagatggaaa ggcagcagct gaccgttact
      541 ctgcccgtcc tggctatagc gaacaccaga caggcttggc ctttgatgtg attgggactg
      601 atggtgattt ggtgacagaa gaaaaagcag cccaatggct cttggatcat gcagctgatt
      661 atggctttgt tgtccgttat ctcaaaggca aggaaaagga aacaggctat atggctgagg
      721 aatggcacct gcgttatgta ggaaaagaag ctaaagaaat tgctgcaagt ggtctcagtt
      781 tggaagaata ctatggcttt gaaggcggag actacgtcga ttaatactct tcgaaaatct
      841 cttcaaacca cgtcagcgtc gccttaccta ctgactgcgt cggttctatt cacaacctca
      901 aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa tctcaaagct gtactttgag
      961 cagcctacag ctagcttcct agtttgctct ttgattttca ttgagtataa aaaataaact
     1021 tttctcttgc aattccagat aaatagtgta taatggatgg gtatgtgaaa aacatacttg
     1081 tgggaggtaa aaatctctaa ttaccgccaa aaccacaaag gaggatttaa aaatggctaa
     1141 aaaagtcgaa aaacttgtaa aattgcaaat ccctgctggt aaagctacac cagctccacc
     1201 ggttggacct gctcttggtc aagctggtat caacatcatg ggattcacaa aagagttcaa
     1261 cgctcgtaca gctgaccaag ctggtatgat cattccagtt gttatctcag tttacgaaga
     1321 taaatcattt actttcgtta cgaaaacacc accagctgct gttcttttga aaaaagctgc
     1381 aggtgttgaa aaaggatcag gtacacctaa taaaactaaa gttgctacag ttactcgtgc
     1441 acaagtacaa gaaattgcag aaactaagat gccagatttg aacgcagcaa acgtagagtc
     1501 tgcaatgcgt atgatcgaag gtactgctcg ttctatggga ttcactgttg ttgactaatc
     1561 aataacacag tagaaaatct cacagcagtc tattagttgc ttttcatact aggcaagtga
     1621 ctgaggcttg tacttgggta cagcaaggga gcttaaggcc gtaggaagag aaaaatagta
     1681 gactgaaaac ccgcaagact tcatcatttc gagaagtgac gtgggagatg aaaatcgatt
     1741 gaaccactta caaggagaat agaaaatggc taaaaaaagc aaacaacttc gtgctgctct
     1801 tgagaaaatc gacagcacaa aagcatacag cgtagaagaa gctgtagcac ttgcaaaaga
     1861 aactaacttt gcaaaatttg acgcaactgt agaagttgct tacaacttga acatcgacgt
     1921 taaaaaagct gaccaacaaa tccgtggagc aatggtattg ccaaacggta ctggtaaaac
     1981 ttcacgtgtt cttgttttcg cacgtggtgc aaaagctgaa gaagcaaaag ctgctggtgc
     2041 agactttgtt ggtgaagatg accttgttgc taaaatcaac gacggttggt tggatttcga
     2101 cgtagttatc gctacacctg atatgatggc tcttgttgga cgtcttggac gtgtccttgg
     2161 accacgtaac ttgatgccaa accctaaaac tggtactgta acaatggatg ttgctaaagc
     2221 agttgaagag tctaaaggtg gtaaaatcac ttaccgtgct gaccgtgcag gtaacgttca
     2281 agcaatcatc ggtaaagtat catttgaagc tgaaaaattg gttgaaaact ttaaagcttt
     2341 caacgaaaca atccaaaaag caaaaccagc tacagctaaa ggaacttacg taacaaactt
     2401 gactatcaca actactcaag gtgttggtat caaagttgac gtaaactcac tttaatcagt
     2461 agttaaagta atgtaaaaaa gttgaagacg ctatgtctca actttttttg atatacgacg
     2521 ggcatgtcgt atatctgagg tgtaaatcct cggtgggcac ctactactgg tgaacccaat
     2581 agcgattccc aagtctgact atcgtgaggt agcggattaa aacggtctgg ggatagaccg
     2641 ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa atcgtggctc
     2701 tacgaacagg aacgtgataa taaggcctat atagcggata aggtatctgg ctggggcgac
     2761 cactatcaat tatagtaaaa tgaaataaga gtaggacgaa tcgatcaggg cagccaaatc
     2821 gatttctaac aatgttttag aagaagagat gtactattct agtttcaatc tactatagta
     2881 gctcagaagt cggtacttaa acgtgctata tcaaaaccag tccttgaaaa acgtggactg
     2941 gtttcgtgtt tggattatta ccttgaacga catgcgttaa aagttag
//
LOCUS       DAVBOU010000092         2909 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBOU010000092 DAVBOU010000000
VERSION     DAVBOU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.093"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ879_002088"
     CDS             complement(64..1005)
                     /locus_tag="VQ879_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3144174.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ879_002089"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ879_002089"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3144175.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRNLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          846 a          688 c          578 g          797 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccgta aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtta cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag cgtcgcctt
//
LOCUS       DAVBOU010000093         2658 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBOU010000093 DAVBOU010000000
VERSION     DAVBOU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.094"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            448..2553
                     /locus_tag="VQ879_002090"
     CDS             448..2553
                     /locus_tag="VQ879_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3144176.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          850 a          480 c          614 g          714 t
ORIGIN      
        1 tcctgatcga tttgtcctgt tcttatttca ttttaatata tagttttgag atggttgata
       61 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
      121 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactctt
      181 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
      241 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
      301 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
      361 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
      421 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
      481 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
      541 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
      601 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
      661 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggtaag
      721 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
      781 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
      841 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
      901 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
      961 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
     1021 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
     1081 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
     1141 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
     1201 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
     1261 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
     1321 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
     1381 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
     1441 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
     1501 gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga aaaccacaca
     1561 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
     1621 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
     1681 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
     1741 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
     1801 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
     1861 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
     1921 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
     1981 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgac
     2041 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
     2101 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
     2161 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
     2221 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acacttgact
     2281 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
     2341 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
     2401 tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat
     2461 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatggaa
     2521 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
     2581 gagccagctg aaaaaaactg gttcctttct aggtacgacg ggcatgtcgt gtagtaggtt
     2641 gaaactagaa tagtacac
//
LOCUS       DAVBOU010000094         2489 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBOU010000094 DAVBOU010000000
VERSION     DAVBOU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.095"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..96
                     /locus_tag="VQ879_002091"
     CDS             <1..96
                     /locus_tag="VQ879_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3144177.1"
                     /translation="HYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            99..686
                     /locus_tag="VQ879_002092"
     CDS             99..686
                     /locus_tag="VQ879_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3144178.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            816..1406
                     /locus_tag="VQ879_002093"
     CDS             816..1406
                     /locus_tag="VQ879_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3144179.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            1406..2242
                     /locus_tag="VQ879_002094"
     CDS             1406..2242
                     /locus_tag="VQ879_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET3144180.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
BASE COUNT          847 a          353 c          455 g          834 t
ORIGIN      
        1 cactacaaga tggaacaacg aatgcctcaa agtccatggg tagaaaggat tgtgcaggta
       61 ttagatttag attatgaaga tttatttcgg aggtaactat gaaaagaata attccagttt
      121 atatattcca acaagtaaat gtcttattgg tatccctata cttactgaaa ttgctttgta
      181 ttggtgagtt aaccatacta cagattctct attgtgcgtc gctcatttct tttttatgga
      241 tgtatggtca acgaaaacaa gtggtcaagg tcaatatgaa aactaggatg aaatggcttg
      301 gtattggatt cgttagccta ctgattataa gcctatgttt tagtctgatt catgctcaag
      361 gaaccacgaa tcaagcaaac ttaattggcc ttcaacatca ggttccttgg ttttcatttt
      421 tattgttctt aatcaatgcg agtatggttg aagaatttct gtatcgagaa attttatgga
      481 acttggtcag aaaattagat attcgagttg ctttgacaag tgttttattt gccttagtac
      541 atcatccagg aaccattcta gcttggtgtt tatatgtttc acttgggatc tttttaggga
      601 tggtgcgcta taaatcggac ttatggggaa gtatgggtct acatttggtg tggaacctat
      661 cagtctatgt cttatttttt ctttaataat agctggtctg tcttacgtat ggattaattt
      721 tgaaataaaa aaactaaatg aattgatttt aaagaaataa aatgctaaca tatatagaag
      781 atgttagcat tttatttcta agaaaggaga atggtatggt tgataaaaga gagaaactga
      841 tgaactcttt caatcagtat ggttttttaa cttttaaaca agtaatagat gaaaatttac
      901 actacaaaac cttattaaaa atggttacag aaggaaaaat cgatgctgaa gaaaaagggt
      961 tatatcgctt acctgatatt tatttagatg agtggtttgt cattcagtat cgatttccaa
     1021 aaggaatctt ttctttggag acagcacttt ggttacatgg tttatctttg actatccctt
     1081 ttaacatgac aatgagtttt ccttatggta cgaataccaa aaacattaag gaagcagata
     1141 tatgtcctat tatcttacgc tctcactata gtgaaggaat tattgaaata gagcgtcttc
     1201 ctggtcaatt tattaaagtt tatgaaattg aacgagtttt ggttgaatgt ctaagaccag
     1261 ttcatcaggt ggatcttcaa attattgcac cagcgtttaa gaaatatttt caacagaatc
     1321 aaattcattt acacaaatta ttttattatg cccaactatt taaagtaact gataagttac
     1381 aatcttatac ggaggtgcta tcttaatgtt ttcaaatgcg aatagcttta aagcaaaaat
     1441 caaaaatatt tcaaaagata agggaattcc agctcaacaa gtacaacaac attatttaat
     1501 tgagcaagtg ttaaagctga tttctactag ttcttataga gattccttca ttgtaaaagg
     1561 agggtatcta ataggtcaaa tgattggact agataagcga accacaatgg atttagatgt
     1621 cactctgaag ggaaccgaaa tgagcagaga aaatttgatt gatatctttg aagagattct
     1681 ttgttctaaa actgatggtt tttcattttc agtagataag ctagaaccta ttcgccaaga
     1741 tgatgaatat ggaggatttt cattaaaatt aaatgcaact tttgatacat taaaggaggt
     1801 tgtttttatt gatattacta ctggtgataa gatcacacca agagaaatta cttattcaat
     1861 gacttctatc tttactaatg aaagcatcaa gatatggaca tataatctag aaactgtact
     1921 tgctgaaaag ttagaaacaa tcattagtag gggattagct tcaacacgcc cacgtgatcg
     1981 atatgatctt ttcaccttgt ataaacttag aaaagaagag attaatcttg aagtattaaa
     2041 aaatgcactt gaaaatacag caaaaaaacg taaaagtaaa gatactattt ataattggga
     2101 agaacaagtg agaggaattg aaatttctga ttatcagaaa gagctatgga ttcgttatca
     2161 acgccaattt aagtatgcta aagatatctc atttgataac tctgttcagg ttattaggga
     2221 aattatgcaa caaatatttt agtacaaaag taactcattc gtaaagcagt gagttgcttt
     2281 ttttattcca acaacctcaa acatgtgata aaaatttcaa ctactcttat ctataataaa
     2341 gctacctgtt ctttgaaaat tgaatccact ccgtcttgat tagcgtgcct gtgtaagtag
     2401 ggaatgagag tatttccctg tgaagggcaa ctggcacaag acgtgtgtga gaattttcta
     2461 acagacacgg agtttatcgt ttccagact
//
LOCUS       DAVBOU010000095         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBOU010000095 DAVBOU010000000
VERSION     DAVBOU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.096"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ879_002095"
     CDS             complement(173..838)
                     /locus_tag="VQ879_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3144181.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ879_002096"
     CDS             complement(852..2231)
                     /locus_tag="VQ879_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3144182.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          565 c          463 g          640 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt c
//
LOCUS       DAVBOU010000096         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBOU010000096 DAVBOU010000000
VERSION     DAVBOU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.097"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ879_002097"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ879_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3144183.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLILQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ879_002098"
     CDS             1681..>2364
                     /locus_tag="VQ879_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3144184.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          430 c          476 g          627 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgattct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBOU010000097         2276 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBOU010000097 DAVBOU010000000
VERSION     DAVBOU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2276
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.098"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            70..608
                     /locus_tag="VQ879_002099"
                     /pseudo
     CDS             70..608
                     /locus_tag="VQ879_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            675..1085
                     /locus_tag="VQ879_002100"
     CDS             675..1085
                     /locus_tag="VQ879_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3144185.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1201..>2276
                     /gene="pavB"
                     /locus_tag="VQ879_002101"
     CDS             1201..>2276
                     /gene="pavB"
                     /locus_tag="VQ879_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3144186.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKA"
BASE COUNT          690 a          443 c          511 g          632 t
ORIGIN      
        1 gacgttgacg cggtttgaag agattttcga agagtataag aaaaaatcag tcccctaaag
       61 gagcagatta tgaagttatt gtctatcgcc atttctagct ataatgcagc agcctatctt
      121 cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt gattatcaat
      181 gacgggtctc aggatcagac tcagaaatcg ctgagtgttt agctagcaag tatcctaata
      241 tcgttagagc catctatcag gaaaataaag gccatggcgg tgcggtcaat cgtggcttgg
      301 cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg gatcctcgtg
      361 cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa gaggtggatg
      421 tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag agtatgagtt
      481 acgagtcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga aatttctcca
      541 aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg cgtgctagcc
      601 agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt acgccccttc
      661 agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg attgggcgtg
      721 aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa ctcaaggtca
      781 atcgactctt ggtagaccaa cttgatttgt cccaagtgag tcatcccaaa atgcgagaat
      841 atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc aaccgatctg
      901 gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag cagaaaaatc
      961 cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa cattctgtct
     1021 tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt tatggattta
     1081 attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt cttagtcctt
     1141 tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa ggagaatcct
     1201 atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct cagtgtcggt
     1261 gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc aagttctgta
     1321 cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagagac atcgggaacg
     1381 aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc gaaacctgag
     1441 ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga agtgagcgag
     1501 gaaacaaact cttctagtct ggatacactt tttgaaaaag atgaagaagc tcaaaaaaat
     1561 ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga tgggacacaa
     1621 gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga aaatacaaaa
     1681 gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg tcctttcact
     1741 gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat gttaactcgt
     1801 ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc taaaaatcct
     1861 gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt agacttaaat
     1921 ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc taatggtact
     1981 caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc tgacttgact
     2041 aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc taaagaaaca
     2101 gttcaaaaag ccgttgcaga taacgttaag gacagtatcg atgttccagc agcctaccta
     2161 gaaaaggcca agggtgaagg tccattcaca gcaggtgtca accatgtgat tccatatgaa
     2221 ctcttcgcag gtgatggtat gttgactcgt ctcttgctca aggcatctga caaggc
//
LOCUS       DAVBOU010000098         1912 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBOU010000098 DAVBOU010000000
VERSION     DAVBOU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.099"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ879_002102"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ879_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>1912)
                     /gene="phtB"
                     /locus_tag="VQ879_002103"
     CDS             complement(1202..>1912)
                     /gene="phtB"
                     /locus_tag="VQ879_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3144187.1"
                     /translation="HQDSGNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGS
                     LIIPHYDHYHNIKFEWFDEGLYEAPKGYSLEDLLATVKYYVEHPNERPHSDNGFGNAS
                     DHVQRNKNGQADTNQTEKPNEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESP
                     EESPEESEEPQVETEKVKEKLREAEDLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDN
                     NTIMAEAEKLLALLKESK"
BASE COUNT          557 a          388 c          293 g          674 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctctt
     1501 ctcgaggggt ttcttcctca ggtttttctg tctgaggttt ctcctcgttt ggtttttccg
     1561 tttgattggt atcagcttga ccatttttgt ttctttgaac atggtcgcta gcgttaccaa
     1621 aaccattatc tgaatgcgga cgttcgtttg gatgttcgac atagtacttg acagtcgcca
     1681 aaagatcctc aagactatac cccttaggtg cctcataaag gccttcgtca aaccactcaa
     1741 atttgatgtt atggtaatgg tcataatgag gtatgattaa actaccgttt ttgacttcta
     1801 cagtatattg aagattgtaa ggcatacgat caagtggcac cttcttagct gctttcacgc
     1861 ggttgtagat agcttctgct ccttttgcct cagtatttcc tgaatcctga tg
//
LOCUS       DAVBOU010000099         1865 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBOU010000099 DAVBOU010000000
VERSION     DAVBOU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1865)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1865)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1865
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.100"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..606)
                     /locus_tag="VQ879_002104"
                     /pseudo
     CDS             complement(1..606)
                     /locus_tag="VQ879_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            848..1188
                     /gene="tnpB"
                     /locus_tag="VQ879_002105"
                     /pseudo
     CDS             848..1188
                     /gene="tnpB"
                     /locus_tag="VQ879_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1221..1865)
                     /locus_tag="VQ879_002106"
                     /pseudo
     CDS             complement(1221..1865)
                     /locus_tag="VQ879_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          542 a          368 c          314 g          641 t
ORIGIN      
        1 aatccgacga taaccataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt
       61 aagctcttgg tccttatctg ttttatctag ctgtttcaag tgatagtagt aggtcgaacg
      121 agctagttta atggctttta gaagaatatc taacgaaaac tcagtcatta attcttgaac
      181 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
      241 aggatggcat tttccgctct caggtactct ccctcttgtt ttctcaacaa tagtataccc
      301 gtttttcctg tattgtgcta gccagttaag aagtatcgta cgacttggga gacagtattc
      361 aagagaaact ctatctttag tccagccttc atgtcagact ttattaatca tttcttgttt
      421 taaatcagga gaatagtaac gattttttcc ttttttgacg aactctattc cgtaacgatc
      481 aatcaattta atcatatacc taagattaga attgtttatc ccaaatttat ttgaaagctt
      541 ctctaagcta tatccttgtt ttctaagttc atagatctga actttatcat cataactcaa
      601 tttcataata aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggggcagtt
      661 cattctacac ccactattat gcgtttttat cattttgaaa tctactgcta atcaatgaag
      721 aagcaaagat caaactaggc agctagttac aagttacgta agcgcgtcat aacaaggtat
      781 ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg aggaaaggta
      841 ttgtactatg ataattcaac taagtgattt aggtcaagtt caccttgttt gtagcaagat
      901 agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga
      961 tcctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct ttaaagccct
     1021 ttactgggat ggtcaaggat tttggctact atataaacgc tttgagaacg gcagactgac
     1081 ttggcccagt acagaaaagg atgtcaaagc tctcacacct gaacaagtag actggcttat
     1141 gaagggcttt tctatcactc caaaaataaa tccatcagaa agtcgtgatt tctattgaaa
     1201 tgaggacttt ctttttatac tcatctgctt tcaaaaagca ttctagtcca tctccgatta
     1261 acgatgggct ttatcacctc cttctccagt ccttgtatga tatcttaaag ttgattcatg
     1321 acatcttcca aagtttgaaa ggctttattt ttaaatccac gtttacgaat ctctttccac
     1381 acttgttcaa tggggttcat ctctggtgtg tatggaggaa taaatgcaaa gccaatatta
     1441 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gaataaaaga
     1501 taatcatctg gataagcttg tgaaagctct tctaaaaaga cgttcatcca ctcagtatta
     1561 catccaccag ctattaagaa aaatgattcg cctgtatggg tccataacaa tagcgaaatt
     1621 ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa caagatccca
     1681 gtttactgat tctaccgaag ccagcctcat cttggtacat caagcgaacc ttatgaaaac
     1741 gtctactggt tttaaagcgc tttcttttct tcttgaattg aaattttatt tttagacgcg
     1801 acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa
     1861 ccatg
//
LOCUS       DAVBOU010000100         1863 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBOU010000100 DAVBOU010000000
VERSION     DAVBOU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.101"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..917)
                     /locus_tag="VQ879_002107"
     CDS             complement(<1..917)
                     /locus_tag="VQ879_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3144188.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCL"
     gene            complement(1362..1760)
                     /locus_tag="VQ879_002108"
     CDS             complement(1362..1760)
                     /locus_tag="VQ879_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3144189.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          502 a          380 c          325 g          656 t
ORIGIN      
        1 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
       61 gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg attctcatta
      121 gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc agaaaataca
      181 tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
      241 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
      301 atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt tttcgctctc
      361 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
      421 ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctggcctg tttcttaagc
      481 gcttttcctt ttctagggta aggcaaatcc tgcttgctta accccaattt tccatgatga
      541 atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac catcatttca
      601 ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt ggtcaagctt
      661 gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcgta gtcggcagaa
      721 taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
      781 gtgtggatag tttgaggagc ttttccaagt agagaggcaa cttctctatt tgattttcct
      841 tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt accttttgta
      901 gtataattgt cttgcatttc tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac
      961 acagaggtgt tttcttatgc ctacaagagc tttcattatt tccattttct tttggatttc
     1021 actctattct gaaaaacttg tgtatattta ctgaagctag caagtcttac ctgtaaattt
     1081 aatgaaagca acacaaaatc cgagagggga atctcggatt aatagataga gagtttttag
     1141 tttaaataaa ttgtttaaaa tatcaacaac atcacttctt ttcttaacct gataagtctt
     1201 gattcctaat tttggggcta cgattatatt gtcctcaata tcgtctagaa agacacaatt
     1261 tctaggttat aactggtatt tatcgatagt tactcatata catcagtcca cctccatact
     1321 tatgtgcgag cctctctttg tattatacct ccatactcac cttacagatt cttttggtaa
     1381 taatatcttt gcctaatgta gagatagtct tgcaaagaaa aaacttcctt gtagccatgt
     1441 ttctgataaa agtccggtgc ctggaactgg taagtattga caaaggcaaa acaacaattt
     1501 cgattcttag cttcactttc tgcctgttgc aatagttttg aaccgattcc ttgccctcgc
     1561 agttcctctt ttacaaacaa atactcgatt tctagccaat ttccaaaagt ctctgctatc
     1621 aaacctgcca ggagattgcc cttttcatct tcgacataaa gattaagtgg ctcactttca
     1681 gcctcttctc tttttgaacg gttataaaca cgaatcagat tccctatttc ttgcgattta
     1741 tgtgattcct tattttccaa tctaatgaaa tgaaataaaa catgcgcaaa tcgattaagg
     1801 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
     1861 cac
//
LOCUS       DAVBOU010000101         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBOU010000101 DAVBOU010000000
VERSION     DAVBOU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.102"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ879_002109"
     CDS             complement(3..968)
                     /locus_tag="VQ879_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3144190.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ879_002110"
     CDS             complement(1086..1499)
                     /locus_tag="VQ879_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3144191.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ879_002111"
     CDS             complement(1496..1732)
                     /locus_tag="VQ879_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3144192.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBOU010000102         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBOU010000102 DAVBOU010000000
VERSION     DAVBOU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.103"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ879_002112"
     CDS             complement(242..1006)
                     /locus_tag="VQ879_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3144193.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ879_002113"
     CDS             1228..1524
                     /locus_tag="VQ879_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3144194.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          522 a          404 c          316 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg atgaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBOU010000103         1478 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBOU010000103 DAVBOU010000000
VERSION     DAVBOU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.104"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            97..504
                     /locus_tag="VQ879_002114"
     CDS             97..504
                     /locus_tag="VQ879_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3144195.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            669..968
                     /locus_tag="VQ879_002115"
     CDS             669..968
                     /locus_tag="VQ879_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3144196.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1080..>1478)
                     /locus_tag="VQ879_002116"
     CDS             complement(1080..>1478)
                     /locus_tag="VQ879_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3144197.1"
                     /translation="SEIIAYNLSCSPNLEQVQTMLEQAFKEKHYENTILHSDQGCQYQ
                     HDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKTFKSLNQLEQAI
                     IDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
BASE COUNT          488 a          286 c          260 g          444 t
ORIGIN      
        1 tttggttcat ttcactataa taataacgat actagataat gaggaaaatg caatggcaaa
       61 cccaactttc ggagaaaaaa agcgaataca gactatattg ctcgctatgg cgtatatgca
      121 gttatcccta atcctgaaca aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg
      181 ttcctaccat gtggagaaat tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag
      241 ttgattgaag agcttggttt cacagcagaa attggtacct attacggaca agctgacgaa
      301 tatttctatt ctcgtcatcg tgatacctac tactacaatc ctgcctacct ctatgaagca
      361 acttctttca aagaagtaca aaagccacta gaaaacttta atcatattgc ctggttccct
      421 attgacgagg ctatccaaaa ccttaaacgt ggtagccata aatgggccat tgaatcttgg
      481 aaaaaacagc ataagattga ctaatactct tcgaaaataa aatttaaacc acgtcagcgt
      541 cgccttaccg tactcaagta tagcctgcgg ctagcttcct agtttgctct ttgattttca
      601 ttgagtataa atcaagcgac tttattcaaa aagtgctata atagaattag aaaatcggag
      661 gaaatattat gaagcttatc aatacgacaa actcacactc gcaacttgta aaaagtcagc
      721 tagaaagtac cgatgcaacc cttgttgagg tttattctgc agggaataca gatgttattt
      781 ttacccaagc tccgcttcac tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg
      841 agcctgaaat cgaaaccatt caagaatttt tcttgaaacg taaaattgat aagacctctg
      901 ttgatgaagc caatatcaag acactctact cagagaaatt aattggaatt tcaatcccaa
      961 tcaagtaaga aaattgagta aaaactcgat ttgagagaaa gtccaataag tctttccata
     1021 ataaaacgca tagtagcagg tgccgaaatg aactgcaccc caaaagttag acaattaatt
     1081 tatccgaagg atttagttct gtattgcaca gggctaagtc cttttagttt taccttaatt
     1141 ctcttgttgt tgtaataatc aatatagtct ataatggctt gttccaattg attaagtgat
     1201 ttaaatgttt tctcatagcc ataaaacatt tcggatttta aaatgccaaa gaaagattcc
     1261 atcataccgt tgtcttggct gtttcccttg cgtgacatgg atgcttgaat tcccttactc
     1321 tctaggaacc gatgataaga atcgtgttgg tattgacagc cttggtcact atggagaatc
     1381 gtattctcat agtgcttctc tttgaatgcc tgttccaaca ttgtttgtac ttgttctaaa
     1441 ttaggcgaac aagaaagatt ataggcgata atttcgct
//
LOCUS       DAVBOU010000104         1455 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBOU010000104 DAVBOU010000000
VERSION     DAVBOU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.105"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ879_002117"
     CDS             <1..559
                     /locus_tag="VQ879_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3144198.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ879_002118"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ879_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3144199.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
BASE COUNT          504 a          208 c          266 g          477 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtga
//
LOCUS       DAVBOU010000105         1409 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBOU010000105 DAVBOU010000000
VERSION     DAVBOU010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.106"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            283..1293
                     /gene="ccpA"
                     /locus_tag="VQ879_002119"
     CDS             283..1293
                     /gene="ccpA"
                     /locus_tag="VQ879_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3144200.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          440 a          232 c          318 g          419 t
ORIGIN      
        1 tcctgttctt atttcatttt actataactt taggagggct tagtttcctc ctttttgttt
       61 agtctaaggt ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc
      121 ttcaaaaaac acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga
      181 aaacgaaatt ttcacatctt cacttttgta agtagatata gagcttcaat cagcacctct
      241 acttgtaaaa gaatatgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca
      301 gtaaccattt atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg
      361 gtcaatggca ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat
      421 cgtttggatt atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact
      481 gtcggtgtcg tgattccaaa tattaccaat ggttattttt cgagtttggc taaggggatt
      541 gatgatattg cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac
      601 gagaaagaag tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat
      661 atgggttatc acttgacaga taaaattcgc tcagaatttt cgcgctcacg tactccgatt
      721 gttctcgcag gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag
      781 caagcaacaa ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt
      841 agcggtccgc tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc
      901 ttgaaaaaag caggaatcac ttatagtgag ggtttggtat ttgaatctaa atatagctat
      961 gatgatggtt acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg
     1021 acaggtgatg agttggcagc aggagtcttg aacggtttgg ctgataaagg tgtttctgtg
     1081 ccagaagatt ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca
     1141 aacttgacaa cgattgccca acctctttat gaccttggtg ctattagtat gcgtatgttg
     1201 accaagatta tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg
     1261 acagaacgta gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc
     1321 ctgattttgt gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg
     1381 cggctggtta aaggctgcgc aacacactg
//
LOCUS       DAVBOU010000106         1044 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBOU010000106 DAVBOU010000000
VERSION     DAVBOU010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.107"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..550
                     /locus_tag="VQ879_002120"
     CDS             <1..550
                     /locus_tag="VQ879_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3144201.1"
                     /translation="ETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNH
                     EEMKRIISKVDLLFQKVSQLFE"
     gene            complement(498..1043)
                     /locus_tag="VQ879_002121"
     CDS             complement(498..1043)
                     /locus_tag="VQ879_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3144202.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          375 a          167 c          149 g          353 t
ORIGIN      
        1 cgaaacaacc tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc
       61 tagcctagtt aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg
      121 aactgaaata ccttgggtat ctatatcaga tatgcctata tctggttatg taactaatac
      181 gagagaatct atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg
      241 aactttatta atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc
      301 cactcataat gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag
      361 agattactta atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat
      421 caaagggaaa acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca
      481 tgaagagatg aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact
      541 ttttgagtaa taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgctcagt
      601 gtagttttag gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt
      661 ttataaaata acggagaaga caagttaaat aatagaaatt ttgaaataat ctctgaactt
      721 tcgaatggtg ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg
      781 attcttgcaa actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta
      841 tgttttaaat aaacttgttc agaggagatg aattgtgtat caatgtagta atcattatcc
      901 aacagagaaa attctaaagg cttaatatta ccaccacgta taattctaac acctttatta
      961 ttaatgctta aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt
     1021 atttttataa caacccaatt cata
//
LOCUS       DAVBOU010000107         1012 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBOU010000107 DAVBOU010000000
VERSION     DAVBOU010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1012
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.108"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..117
                     /locus_tag="VQ879_002122"
     CDS             <1..117
                     /locus_tag="VQ879_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3144203.1"
                     /translation="KKDYIEFKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(414..701)
                     /locus_tag="VQ879_002123"
                     /pseudo
     CDS             complement(414..701)
                     /locus_tag="VQ879_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            700..963
                     /locus_tag="VQ879_002124"
                     /pseudo
     CDS             700..963
                     /locus_tag="VQ879_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          376 a          157 c          176 g          303 t
ORIGIN      
        1 aaaaaagact acattgaatt taaacgtgtt ggtatctttg atgggaaagc agtagaagtt
       61 actcttcgag aaccttattc gagagatcta ctgcaggttg tcaagtcaat aaagtaactg
      121 acaccacgag tataattatt agaaacgtgg aatcttatta aattttataa taaatatatt
      181 aaatgaaaaa ttattagata taaacttatg taataaaaca ttgaggaaat aataaaaatc
      241 tatgggtaat gttctgaaag tacttttagg ttaggagaga aatataatga tttttgaaaa
      301 ttgattcaaa aaatagcgaa ttgtagaaaa cgcttaacaa atggtgtata atagacttcc
      361 agcgaaacaa aatatgctac aataaaccta tgaattataa agtaacctta tactcatctg
      421 tcttcacaaa gcattctagt ccatctccga ttaacgatgg actttatcat ctccttctcc
      481 agtccttgta tgacatcttc caaagttcga aaggctttat tcttaaatcc acgtttacga
      541 atctctttcc acacttattc aatggggttc atttctggtg tgtatggagg aataaatgca
      601 aagccaatat tagtcggaat ctttaaggca cttgatttat gccatatagc attgtccata
      661 acgaataaaa gataatcatc tggataagct tgtgaaagct tggctgacag tggttatcaa
      721 gggctcatga agatatatct tcaagcacaa actccacgta aatccagcaa actcaagccg
      781 ctaacagctg aagataaagc ctataaccat gcgctatcta aggagagaag caaggttgag
      841 aatatttttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
      901 aaacgcttcg gattacgaat gaatttgatt gctgatatta tcaatcatga actaggattc
      961 tagttttgca ggaagtctaa taaatgtata agaaaaagga ggaaaaagga tg
//
LOCUS       DAVBOU010000108         1000 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBOU010000108 DAVBOU010000000
VERSION     DAVBOU010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.109"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..129
                     /locus_tag="VQ879_002125"
     CDS             <1..129
                     /locus_tag="VQ879_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3144204.1"
                     /translation="AARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDESIK"
     gene            113..562
                     /locus_tag="VQ879_002126"
     CDS             113..562
                     /locus_tag="VQ879_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144205.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            555..935
                     /locus_tag="VQ879_002127"
     CDS             555..935
                     /locus_tag="VQ879_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144206.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
BASE COUNT          365 a          157 c          179 g          299 t
ORIGIN      
        1 gctgctagaa aagtctctag taatagtcag ctctataaac aagctggtaa tagtgtaacc
       61 gttcctgtga ttgccgcaat cgcaaagaaa ttaaaagaaa tagaggaaaa agatgaaagc
      121 attaaataaa gaatcaatac tagattgtga tgaattagaa acagaattac atgatgcaga
      181 aatcaaacag ctggatgaac aattattttt gatgcccaat tatccatgtg agtttgaagt
      241 aacattttta gatgattacc ataaaaaaca caactaccca ctattttacg agtcctatct
      301 tcaaaacgtt atggaattcc ttgaaagtca agacataaag aatggggttg atgcctttgt
      361 agatgatcat caaaatctcg tttttgtttt atatggacaa ggctatcgag cagagggaaa
      421 agagggaata cttacaactc aagtaactgt aaaagcttat gatgaagaca agaaaccgat
      481 taacttcgca aatttattag attccttaat cgtctcagaa tatcaaatgg aaccgaatct
      541 ttggaaggtc tcccatgatt gatctctatc taagtaaaaa tagccaaaga aatcaacttc
      601 ttttggattt ctttcaaaag tatggcatag aggtcactcc tcattctatt tctgaaatga
      661 caaaggacaa attaattgaa atgatgagct attcttcaga ttgttttgag tttctatctc
      721 ccaatttatt acgatttaag aaccgtgaca atctaagatt aacggatttc attgaaatga
      781 tattaaaaaa tcctgaacta tgcatcaggc ttcctcttgc ggtttcaaat aagagagttt
      841 atccaaatct gaatttggaa gaggctagag ctctattgcc aagagatacg aaacaattga
      901 tttacatggc acaaacacat tatttatcta gttaaaggag aagcaatatg gctgaacgat
      961 tttgggagaa cttgtccatt attttggctg aaagaaatat
//
LOCUS       DAVBOU010000109          938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBOU010000109 DAVBOU010000000
VERSION     DAVBOU010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.110"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            537..>938
                     /locus_tag="VQ879_002128"
     CDS             537..>938
                     /locus_tag="VQ879_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3144207.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGN"
BASE COUNT          324 a          147 c          162 g          305 t
ORIGIN      
        1 ctataaatca attttccttt cctaatcgat ttgttcatat cttatttcaa tccattataa
       61 atagtgagaa atatctatcc tatcttctag aatgtcttcc aaacgtggaa actctcgtaa
      121 acaaagaggt tttagaggcc tatttaccgt ggactaaagt tgtacaagaa aagtgcaaat
      181 aagaaatctc cagattagga actatatatg agttcactaa tctggagatt tttcaataga
      241 cttcgttatt gggcggttag gatatgatca ctgacttcgt cagtcttatc tacaacctca
      301 aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt actctttgat tttcattgag
      361 tattagaaca gaaaaaatgc ttggagtatt tgtttgtgtg tttattttta tataacaaac
      421 tataaacaaa acaaaaatat aaaaaaagag acaaaaaaga acagaaagta attgacaacg
      481 gtttcatata gtgttatact tatggcataa agttaatgga aagaagggaa aaacttatgg
      541 tattagatta tttctttgac aaaaaccttg tgttttgctt agaagcggat aatcaagaac
      601 atctctttga tcaggttgca actttattgg aagaacgaga aattgtaact ccaacttatc
      661 gtgaagcctt gatcacgcgt gaaaagtcat ttccaactgg tttagatatg gaatttctag
      721 gaaagaactt gccaaatgta gcgattcctc acacagatat tgttcataat ctagctgaga
      781 aagtggtggt tgttcgatta gaaaaaccag taacttttca caatatgata gctcctgata
      841 aggaagtaga agtatcccta ctcttcttta ttattaacaa ttcaagttca agtcaaacaa
      901 atattctggc tcagttgatg gactttttca caggaaat
//
LOCUS       DAVBOU010000110          775 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBOU010000110 DAVBOU010000000
VERSION     DAVBOU010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.111"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ879_002129"
     CDS             3..305
                     /locus_tag="VQ879_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3144208.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..775
                     /locus_tag="VQ879_002130"
                     /pseudo
     CDS             313..775
                     /locus_tag="VQ879_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          254 a          142 c          160 g          219 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat tattctggta aaaagaaatt
      721 tcacgctatg aagtctcaag cgattgtcac aagtcaaggg agaattgttt ctttg
//
LOCUS       DAVBOU010000111          758 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBOU010000111 DAVBOU010000000
VERSION     DAVBOU010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.112"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..>758
                     /locus_tag="VQ879_002131"
     CDS             <1..>758
                     /locus_tag="VQ879_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3144209.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          297 a          110 c          120 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaag
//
LOCUS       DAVBOU010000112          734 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBOU010000112 DAVBOU010000000
VERSION     DAVBOU010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..734
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.113"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            98..734
                     /locus_tag="VQ879_002132"
                     /pseudo
     CDS             98..734
                     /locus_tag="VQ879_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842088.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
BASE COUNT          249 a          118 c          175 g          192 t
ORIGIN      
        1 aggtaccaga ctcttatttc ctttcagacg agaaggtcaa gcaactaact ctgagacttt
       61 gaaagcacta ggaaatttga atccatcaaa aagtggcgtg agcggtaaag tgtattattc
      121 agaaggtctt gcgccaactt tagttcgtgg aaaaggagaa ggatttaagg ttgctattcc
      181 ttgtatgaca ccagatagat tagacaaaag acaaaatggt agacgcttta aggaaaacca
      241 agagccgatg tttactttaa atactcagga tcgtcatggc attgtcgttg ttggagattt
      301 accgactagt tttaaggaga caggtcgtgt ctatggaagt gagggcttat ctccaacact
      361 gactacgatg caaggaggag ataaaatccc caaaatacta attccagaac caatccaatt
      421 tctaaaagta cgggaagcaa cgaaaaaagg atatgctcaa gcagagattg gggattcaat
      481 caatttggaa agaccaagtt ctcagtatcg tcgtggtaga gttggcaaag gtatagctaa
      541 tacgttaaca actgtggtag agttggcaaa ggtatagcta atacgttaac aactagtggt
      601 caaatgggag tagtagtggc tagctatgaa ggagaagata aacaagttta ccaagtagct
      661 ggtgttttaa tagatggaca attttaccgt ttgagaatac gacgaatcac tcctaaagag
      721 tgttttcgat tgca
//
LOCUS       DAVBOU010000113          713 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBOU010000113 DAVBOU010000000
VERSION     DAVBOU010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.114"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..>713
                     /locus_tag="VQ879_002133"
     CDS             <1..>713
                     /locus_tag="VQ879_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET3144210.1"
                     /translation="ELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEGVAYNAHYRAHGY
                     HPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFRMDSGFATPKLYD
                     LIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETLYQAGSWSHKRR
                     VCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKEMKEGFFGDKTD
                     SSTLIKNEVRMMMSCIAYN"
BASE COUNT          203 a          161 c          142 g          207 t
ORIGIN      
        1 tgaattggtc gaattctttt tacagtttca ccagctaaac caactcattg tagatatcga
       61 ttctacccat ttcacaactt atggcaagca agaaggtgtt gcttataacg cccactatcg
      121 tgctcatggc tatcatcctc tttatgcttt cgaggggaag acaggttatt gtttcaatgc
      181 ccagcttcgt cctggtaatc gttattgttc tgaagaggca gacagcttta tcacacctgt
      241 tttagaacgg tttaatcaac ttctctttcg aatggatagt ggctttgcga ccccaaaatt
      301 atacgattta attgaaaaaa cagggcaata ctacctcata aaactcaaga aaaatactgt
      361 tctgagccgt cttggagacc tttccctccc ttgcccacag gatgaggact taaccatctt
      421 gccccactcc gcctactcag aaactctcta tcaagcagga tcttggtcgc acaagcgtcg
      481 tgtctgccag ttctctgaac gaaaagaagg aaacttgttc tacgatgtta tttctctcgt
      541 tacaaatatg acgagtggaa caagccaaga ccagtttcag ctttatcgtg gacgtggtca
      601 agccgagaat ttcatcaagg agatgaagga gggatttttt ggcgataaaa cggatagttc
      661 aaccttaatc aaaaacgaag ttcgtatgat gatgagctgt atcgcctaca atc
//
LOCUS       DAVBOU010000114          693 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBOU010000114 DAVBOU010000000
VERSION     DAVBOU010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.115"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            98..>693
                     /locus_tag="VQ879_002134"
     CDS             98..>693
                     /locus_tag="VQ879_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3144211.1"
                     /translation="MSGKVYYSEGLAPTLVRGKGEGFKVAIPCMTPDRLDKRQNGRRF
                     KENQEPMFTLNTQDRHGIVVVGDLPTSFKETGRVYGSEGLSPTLTTMQGGDKIPKILI
                     PEPIQFLKVREATKKGYAQAEIGDSINLERPSSQYRRGRVGKGIANTLTTSGQMGVVV
                     ASYEGEDKQVYHVAGVLIDGQFYRLRIRRITPKECFRL"
BASE COUNT          240 a          117 c          161 g          175 t
ORIGIN      
        1 aggtaccaga ctcttatttc ctttcagacg agaaggtcaa acaactaact ctgagacttt
       61 aaaaacacta gggaatttga atccatcaaa aagtggaatg agcggtaaag tctattattc
      121 agaaggtctt gcaccaacct tagttcgtgg aaaaggagaa ggattcaagg ttgcgattcc
      181 ttgtatgaca ccagacagat tagacaagag acaaaatggg agacgcttta aggaaaacca
      241 agagccgatg tttactttaa atactcagga tcgtcatggt attgtcgttg ttggagattt
      301 accgactagc tttaaggaga caggtcgagt ctatggaagc gagggcttat ctccaacact
      361 gactacgatg caaggaggag ataaaattcc caaaatactg attccagaac caatccaatt
      421 tctaaaagtc cgggaagcaa ctaaaaaagg gtatgctcaa gcagagattg gagattcaat
      481 caatttagaa agaccaagtt ctcagtatcg tcgtggtaga gttggaaaag gtatagcgaa
      541 tacattaaca actagtggtc aaatgggagt agtagtggct agctatgaag gagaagataa
      601 acaagtttac catgtagctg gtgttttaat agatggacaa ttttaccgtt tgagaatacg
      661 acgaatcact cctaaagagt gttttcgact gca
//
LOCUS       DAVBOU010000115          692 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBOU010000115 DAVBOU010000000
VERSION     DAVBOU010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..692
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.116"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ879_002135"
     tRNA            complement(74..147)
                     /locus_tag="VQ879_002135"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ879_002136"
     tRNA            complement(157..242)
                     /locus_tag="VQ879_002136"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ879_002137"
     tRNA            complement(250..321)
                     /locus_tag="VQ879_002137"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ879_002138"
     tRNA            complement(344..416)
                     /locus_tag="VQ879_002138"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ879_002139"
     tRNA            complement(435..516)
                     /locus_tag="VQ879_002139"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ879_002140"
     tRNA            complement(522..594)
                     /locus_tag="VQ879_002140"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ879_002141"
     tRNA            complement(619..691)
                     /locus_tag="VQ879_002141"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
BASE COUNT          179 a          204 c          149 g          160 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ct
//
LOCUS       DAVBOU010000116          630 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBOU010000116 DAVBOU010000000
VERSION     DAVBOU010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.117"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ879_002142"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ879_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          207 a           76 c          119 g          228 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta
//
LOCUS       DAVBOU010000117          604 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBOU010000117 DAVBOU010000000
VERSION     DAVBOU010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.118"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..555
                     /locus_tag="VQ879_002143"
                     /pseudo
     CDS             1..555
                     /locus_tag="VQ879_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          208 a          103 c          118 g          175 t
ORIGIN      
        1 aaggaacaaa accaagaaaa gttgatagag atagacttaa aaactatctt actgacaatc
       61 cagacgctta tttgactgaa atagcttctg actttggctg tcatccaact accatccact
      121 atgcgctcaa agctatgggc tacactcgaa aaaagaacca cacctactat gaacaagacc
      181 cagaaaaagt agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt
      241 agattgacga aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag
      301 gtcagttaag aagaggcaaa gtatctggaa gaagatatca gagaatttct ttggttgcag
      361 gtctaacaaa tgaatggtga gttaatcgct ccaatgactt acgaagagac gatgacgagc
      421 gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac accatcggtt
      481 attattatgg ataatgcaag attccataga atgggtaagt tagaactttt atgcgaggag
      541 tttgggtata aactttggct ctataatatt tgtagtgggt aaatccacta tagatattat
      601 ggag
//
LOCUS       DAVBOU010000118          601 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBOU010000118 DAVBOU010000000
VERSION     DAVBOU010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.119"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..>601
                     /locus_tag="VQ879_002144"
     CDS             <1..>601
                     /locus_tag="VQ879_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3144212.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT          192 a          135 c          122 g          152 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattcatcaa gatttacttg ataataaagg tcgacaagtt gattttgagg
      541 ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg
      601 a
//
LOCUS       DAVBOU010000119          599 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBOU010000119 DAVBOU010000000
VERSION     DAVBOU010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.120"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ879_002145"
     CDS             complement(21..500)
                     /locus_tag="VQ879_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3144213.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          160 a          139 c           78 g          222 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaactgca caaaaaaga
//
LOCUS       DAVBOU010000120          584 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBOU010000120 DAVBOU010000000
VERSION     DAVBOU010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.121"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..202)
                     /locus_tag="VQ879_002146"
     CDS             complement(<1..202)
                     /locus_tag="VQ879_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3144214.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKYAKGG
                     RKPKLSLEDLLMATLQYVREYRT"
     gene            197..451
                     /locus_tag="VQ879_002147"
     CDS             197..451
                     /locus_tag="VQ879_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3144215.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT          188 a           86 c          116 g          194 t
ORIGIN      
        1 aagtgcgata ttctcgcaca tattgaagag tggccataag aaggtcttct aggcttaatt
       61 taggttttcg tccacctttt gcgtatttaa gttgataagc tgtttttaat acagctaata
      121 tctcttcaaa agtcgtgcgc tgaacaccaa caagacgctt aaatcgtgca tcagttagtt
      181 gtttacttgc ttcataattc atagaactac tataccatat tttgtttcgc aggaagtcta
      241 ttggaaagta agaaatattg gagctgaggc gattagaaga aattgtgagc gtggtgctat
      301 tttttcaggt aaaataaaac atcacgaaga ttctcagttt aaaggagagc actatgttga
      361 atgttatgct gttttagata atacggttat agcaagagat agaataacag tccctatcga
      421 tccgttatgt ggaaaagatt ttatagagta gcatataatt gattcttaac tggaatactc
      481 tctatctctt tacatcaaga aaatgactaa acagggaagt ttgccttctt cccttttttt
      541 gttatactag tagaagaaaa aaatagaaag atttgtggga gtga
//
LOCUS       DAVBOU010000121          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBOU010000121 DAVBOU010000000
VERSION     DAVBOU010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.122"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ879_002148"
     CDS             complement(<1..534)
                     /locus_tag="VQ879_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3144216.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBOU010000122          512 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBOU010000122 DAVBOU010000000
VERSION     DAVBOU010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..512
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.123"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(<1..159)
                     /locus_tag="VQ879_002149"
     CDS             complement(<1..159)
                     /locus_tag="VQ879_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3144217.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQILRNTIYGWLKLKEK
                     TGELNHQVK"
     gene            complement(267..340)
                     /locus_tag="VQ879_002150"
     tRNA            complement(267..340)
                     /locus_tag="VQ879_002150"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(304..306),aa:Asn,seq:gtt)
     gene            complement(346..461)
                     /gene="rrf"
                     /locus_tag="VQ879_002151"
     rRNA            complement(346..461)
                     /gene="rrf"
                     /locus_tag="VQ879_002151"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          154 a          112 c           84 g          162 t
ORIGIN      
        1 ttttacttgg tggtttagct ctcccgtttt ctcttttagc tttaaccagc cataaatggt
       61 attacgtaag atttggaaaa cgtgtgacgc ttctgttata ctacctgttc gctcacaata
      121 agagagaact tttttacgaa aatctattga atatgccata aaaagattat accacattgt
      181 gtactatttt tggttcattt tactataaca cgaaatagat tattattaca taacaaaaaa
      241 gaggtctaaa cctcttaact caattactcc gccagtagga ctcgaaccta cgacatcatg
      301 attaacagtc atgcgctact accaactgag ctatggcgga ttaaagctaa gcgacttccc
      361 tatctcacag ggggcaaccc ccaactactt ccggcgttct agggcttaac ttctgtgttc
      421 ggtatgggta caggtgtatc tcctaggcta tcgtcactta actctgagta atacctactc
      481 aaaattgaat atctattcaa ttcaagaaaa cc
//
LOCUS       DAVBOU010000123          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBOU010000123 DAVBOU010000000
VERSION     DAVBOU010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.124"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ879_002152"
     CDS             <1..>501
                     /locus_tag="VQ879_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3144218.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBOU010000124          500 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVBOU010000124 DAVBOU010000000
VERSION     DAVBOU010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.125"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            1..500
                     /locus_tag="VQ879_002153"
                     /pseudo
     CDS             1..500
                     /locus_tag="VQ879_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT          151 a           98 c          112 g          139 t
ORIGIN      
        1 gagttcggac tcgactctct ccttcaagaa acacgtggtg gtcgtaacca tgcatatatg
       61 acagttgagg aagagaaagc ctttcttgcc cgccatttga aggctacaga ggcaggagaa
      121 tttgttacaa ttgatgcctt atttcaggct tataaaaagg agttaggtca ttcctacaca
      181 cgtgatgcct tctatcaact gttgaagcgc catggttggc gaaatattac gccacgtcca
      241 gaacatccta agaaagcaga cgctcaaacc attgttgcgt ctaaaaataa aatctcaatt
      301 caagaagaca agaaagcgtt ttaaatatag tagacgtttt cataaggttc gcttgatgta
      361 ccaagatgag gctggtttcg gtagaatcag taaactggga tcttgttggt ctccaatagg
      421 agtaggtcca catgtccata gtcactatat acgagaattt cgctattatt atggagctgt
      481 tgatgcctat acaggcgaat
//
LOCUS       DAVBOU010000125          482 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVBOU010000125 DAVBOU010000000
VERSION     DAVBOU010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.126"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            373..482
                     /locus_tag="VQ879_002154"
                     /pseudo
     CDS             373..482
                     /locus_tag="VQ879_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          192 a           73 c           76 g          141 t
ORIGIN      
        1 aatcaaaaag cattatataa tagtgatatg aaatcaacta aagaagaaat ccaaaccatc
       61 aaaacacttt taaaagactc tcgtacagct aaatatcata aacgccttca aatcgttcta
      121 tagtaaaatg aaataagaac agtacaaatc gatcaggaca gtcaaattga tttctaacaa
      181 tgttttagaa gtagaggtgt actattctag tttcaatcta ttatatttcg tctgatgggc
      241 aaatcttata aagagattat agaactttta tagtagtttg aaataagatg tgaacaactc
      301 tatcaggaaa gtcaaattaa tttatagaaa tattttagca gccaaggtgt actgttatag
      361 attcaataca ctatagactg taatcaaaca acgatttggc gaaatgtaaa aaaatatgag
      421 gagttcggac tcgactctct ccttcaagaa acacgtggtg gtcgtaacca tgcatatatg
      481 ac
//
LOCUS       DAVBOU010000126          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVBOU010000126 DAVBOU010000000
VERSION     DAVBOU010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.127"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ879_002155"
     CDS             complement(91..228)
                     /locus_tag="VQ879_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3144219.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ879_002156"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ879_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBOU010000127          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVBOU010000127 DAVBOU010000000
VERSION     DAVBOU010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.128"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ879_002157"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ879_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBOU010000128          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVBOU010000128 DAVBOU010000000
VERSION     DAVBOU010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.129"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ879_002158"
     CDS             116..>297
                     /locus_tag="VQ879_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3144220.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBOU010000129          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVBOU010000129 DAVBOU010000000
VERSION     DAVBOU010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.130"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           64 t
ORIGIN      
        1 tctgaggtgt aagtcctcgg tgggcacctg ttaccggtga acccaatagc gattcccaag
       61 cctgactatc gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taaatctgac
      121 gctggaaata agaatcgtca gaggaaggga tagcgaactc gtggctctac gaacaggaac
      181 gtgatagtaa ggcgtatata gcggataagg gggcctcaaa ctctaaagtt caaaaaggta
      241 gtcgtaacct atatgcgtaa atcacgagag caactgaatt tgtc
//
LOCUS       DAVBOU010000130          251 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVBOU010000130 DAVBOU010000000
VERSION     DAVBOU010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.denovo.131"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..>251
                     /locus_tag="VQ879_002159"
     CDS             <1..>251
                     /locus_tag="VQ879_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3144221.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKG"
BASE COUNT           84 a           51 c           60 g           56 t
ORIGIN      
        1 ccgattcgtc atccagaacg tttaggaaaa ccaaatgcgc aaattaccta cactgatgat
       61 gagattcaag tagccaagtt ggcaggcaag tacacaacag aagacggtta tatctttgat
      121 cctcgtgata taaccagtga tgagggggat gcctatgtaa ctccacatat gacccatagc
      181 cactggatta aaaaagatag tttgtctgaa gctgagagag cggcagccca ggcttatgct
      241 aaagagaaag g
//
LOCUS       DAVBOU010000131        10365 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 99-03
            SAMEA1012444-rid20182613.guided.066, whole genome shotgun sequence.
ACCESSION   DAVBOU010000131 DAVBOU010000000
VERSION     DAVBOU010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012444
            Sequence Read Archive: ERR046712
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979931.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979931.1
            Genome Coverage       :: 310x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:21:49
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,170
            CDSs (total)                      :: 2,125
            Genes (coding)                    :: 1,989
            CDSs (with protein)               :: 1,989
            Genes (RNA)                       :: 45
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 83 of 136
            Pseudo Genes (incomplete)         :: 52 of 136
            Pseudo Genes (internal stop)      :: 36 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012444-rid20182613.guided.066"
                     /strain="NIG 99-03"
                     /db_xref="taxon:1313"
     gene            <1..2002
                     /locus_tag="VQ879_002160"
     CDS             <1..2002
                     /locus_tag="VQ879_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3144222.1"
                     /translation="SRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNFI
                     WTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLLL
                     LILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDIS
                     NASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRVE
                     SLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFVF
                     LLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLIIT
                     TAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVM
                     RKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKE
                     KSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDL
                     TSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYH
                     DEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTA
                     DRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            1999..3000
                     /locus_tag="VQ879_002161"
     CDS             1999..3000
                     /locus_tag="VQ879_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3144223.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2997..3932
                     /locus_tag="VQ879_002162"
     CDS             2997..3932
                     /locus_tag="VQ879_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3144224.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            4177..4293
                     /locus_tag="VQ879_002163"
     CDS             4177..4293
                     /locus_tag="VQ879_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3144225.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ879_002164"
     CDS             4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ879_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3144226.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            6347..6514
                     /locus_tag="VQ879_002165"
     CDS             6347..6514
                     /locus_tag="VQ879_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3144227.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(6574..6927)
                     /locus_tag="VQ879_002166"
     CDS             complement(6574..6927)
                     /locus_tag="VQ879_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3144228.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            7432..7854
                     /locus_tag="VQ879_002167"
     CDS             7432..7854
                     /locus_tag="VQ879_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3144229.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            7851..8081
                     /locus_tag="VQ879_002168"
     CDS             7851..8081
                     /locus_tag="VQ879_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3144230.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            8542..8745
                     /locus_tag="VQ879_002169"
     CDS             8542..8745
                     /locus_tag="VQ879_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3144231.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            8827..10044
                     /locus_tag="VQ879_002170"
     CDS             8827..10044
                     /locus_tag="VQ879_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3144232.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3475 a         1840 c         2093 g         2957 t
ORIGIN      
        1 cagccgatac ccacttgaaa actatcaact ggatttttat gtggataata gctggggctg
       61 gcttccgtgg aactggtcgg acgggattgg aaaacaggtc atgtatggac tatatgccat
      121 taccaatttt atttggacaa tcagtttgta tgtttccaat gcgacaggtt acttagtaca
      181 ggaagcctat tccttagact tcatttccgc tacagcagat tccattggta agaatatgca
      241 gaccttagct ggtgtgagtg caaacggatt ttcaacagag ggtttctatg ttggattcct
      301 cttactcttg attttggttc ttggggttta tgttgcctat acgggactga taaagagaga
      361 aaccacaaag gcaattcatg ccattatgaa ttttgtgctg gtgtttatcc tatcggcttc
      421 ctttattgcc tacgctcccg actacattaa aaaaatcaat gacttttcat cagacatcag
      481 taatgccagt ttatcacttg gcacgaagat tgtcatgccc cattccgata gtcaaggcaa
      541 ggacagcgtg gacttaatca gagatagcct gttttccata caggttcagc aaccgtggct
      601 actgcttcaa tacaacagtt cagacattga aagtatcggt attgaccgtg tggaaagcct
      661 gctctccacc agcccagatt ccaacaatgg cgaagacaga gaaaaaattg ttgcggaaga
      721 aattgaagac agaagcaata ccaatctaac cattacaaag accattaacc gtttaggtac
      781 agtcttcttc ctatttgtct tcaatattgg gatttccata tttgtattcc tattaacagg
      841 aatcatgatt ttctcgcagg tactttttat catctatgct atgtttctgc ctgtgagctt
      901 tattttaagc atgattccat catttgatgg tatgtcaaaa cgagccataa caaagctctt
      961 taataccatt ttgacacgag ctggaatcac attgattatt acgacagcat ttagtatttc
     1021 aaccatgctc tataccttat cggctggtta tccgttcttt ttgattgctt ttctacagat
     1081 tgtgaccttt gcaggaatct acttcaagct gggcgattta atgagtatgt tttctctaca
     1141 gagtaacgat tctcaaagtg tgggaagtcg tgtgatgaga aaacctcgta tgcttatgca
     1201 cgctcacatg caccgtctac agcggaaact tggacgttcc atgactactc taggggctgg
     1261 gtctgccatt gttacaggta aaaaaggaca gtcgggttcg gggagttctg caaggacaca
     1321 agcagatcac tcccgaccag acggaaagga aaaatcaaca cttggaaaac gtatcggtca
     1381 aaccatcggt acagtagctg ataccaaaga cagaatggta gacactgcta gtggtttgaa
     1441 agaacaggtt aaagatttgc cgaccaatgc aagatatgca gtatatcaag gaaaatccaa
     1501 agtaaaagag aatgtccgtg atttaaccag tagtatttct caaaccaaag cggacagagc
     1561 cagtggacgc aaggaacagc aggaacaaag gcgaaaaacc attgcgaagc gtcgctctga
     1621 aatggaacag gtcaaacaga aaaaacagcc tgcttcttct gttcatgaaa gaccgactac
     1681 aagacaagaa caatatcatg atgaacagac ctcaaaacag tctaatattc agacttcata
     1741 taaggaatct caacaagcca aacaagagcg tccagcagtt aagtccgatt tttcaagtcc
     1801 aaaagtggaa cgccaaggca ataccgttca agaaaaaacc gttcaaaagc cagcaacttc
     1861 aaccactaca gcagatagaa cttcacaacg tccaatcaca aaagaacgtc cgtctactgt
     1921 tcaaagagta ccactacaaa atacaagaag tagaccacca atcaaaaccg ccaccattaa
     1981 gaaagtcggt aagaaaccat gaagttgaaa actttagtga ttggtggttc tggattattc
     2041 ttgatggtct tctcactgct tctgtttgtt gccattttat tttcagatga acaggacagc
     2101 ggaatttcca atattcatta tggaggtgtg aatgtttccg cagaagtgct ggctcataag
     2161 cctatggtag aaaaatatgc caaagaatat ggcgttgaag aatatgtcaa catacttctt
     2221 gcgattatac aggtggaatc gggcggtact gcggaagatg ttatgcagtc ctcggaatcc
     2281 ctcggtcttc cacctaattc attgagtaca gaagaatcca ttaagcaagg tgtgaagtat
     2341 ttcagtgaat tattagccag tagcgaaagg ctcagtgtag atttagaatc ggttatccag
     2401 tcctacaatt atggtggtgg tttcttaggg tatgtggcta atcgtggaaa taaatatacc
     2461 tttgaactgg ctcaaagttt ctcaaaagag tattcaggtg gcgaaaaagt gtcttacccc
     2521 aatcccatag ccatacctat caatgggggc tggcgataca actatggcaa tatgttttat
     2581 gtgcaactgg taacgcagta tcttgtcaca acagagtttg atgatgatac ggtacaagcc
     2641 atcatggacg aagcactgaa atatgagggc tggcgatacg tttacggtgg agcttccccg
     2701 actacttctt ttgattgtag cggactgaca caatggacgt atggaaaagc tggaattaac
     2761 ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc atatcccact atcggaagca
     2821 caagctggcg atttggtttt ctttcattct acctataacg ctggctctta tattactcat
     2881 gttgggatat accttggcaa taaccgtatg tttcatgcag gcgacccaat cggttatgcc
     2941 gacttaacaa gcccctactg gcaacagcat ttagtgggag caggacgaat caaacaatga
     3001 gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa taaagaaaaa cagataccaa
     3061 aggaaaagaa acctcgtgtc tactataagg tcaatcctca taaaaaggtt gtgattgcct
     3121 tgtgggtact tttagggctt agtttcagct ttgcgatatt caagcacttt acagctatag
     3181 atactcatac tattcacgaa acaactatca tagaaaagga atacgttgat actcatcatg
     3241 tagaaaattt tgtagagaac tttgcgaaag tctactattc atgggagcaa tccgataagt
     3301 ccattgataa tcgaatggaa agtctaaaag gctatctgac agatgaactt caagctctca
     3361 atgttgatac agtacgcaaa gatattcctg tatcgtcttc tgtaagagga tttcagatat
     3421 ggacggtaga gccaactggc gacaatgagt ttaatgtaac ctacagtgta gaccagctca
     3481 ttacagaggg agaaaataca aagaccgtcc actctgctta tatagtgagt gtctatgtag
     3541 atggttctgg aaatatggta ctggttaaga atccgaccat taccaacata cctaagaaat
     3601 caagttataa accaaaagcc attgaaagtg aggggacggt tgattccatt acaaccaatg
     3661 aaatcaatga gtttttaacg acgttcttca agctctatcc tacagcgaca gccagtgaac
     3721 tttcctacta tgtgaatgac gggatattaa aaccaatcgg aaaagagtac atctttcaag
     3781 aactggtaaa tcctattcac aatcgtaagg ataatcaagt cacggtatcg ctgacagtgg
     3841 agtatatcga ccagcagacc aaagcaacgc aggtatctca atttgatttg gtacttgaaa
     3901 agaacgggag taattggaag attatagaat aacaaatatt ggtacattat tacagctatt
     3961 ttgtaatcac gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttat
     4021 gtgctattat ttaagtatct atttaaaagg agttaataaa tatgcggcaa ggtattctta
     4081 aataaactgt caatttgata gtggaaacaa ataattggat gtcctttttt aggagggctt
     4141 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat
     4201 atctgtatgc tttgtatgcc tatggttatg cataaaaatc ccagtgataa gagtatttat
     4261 cactgggatt tttatgccct tttgggcttt tgaatggagg aaaatcacat gaaaattatt
     4321 aatattggag ttttagctca tgttgatgcg ggaaaaacta ccttaacaga aagcttatta
     4381 tataacagtg gagcgattac agaattagga agcgtggaca gaggtacaac gaaaacggat
     4441 aatacgcttt tagaacgtca gagaggaatt acaattcaga cggcgataac ctcttttcag
     4501 tggaaaaata ctaagataaa catcatagac acgccaggac atatggattt tttagcagaa
     4561 gtatatcgtt cattatcagt attagatggg gcaattctac tgatttctgc aaaagatggc
     4621 gtacaagcac aaactcgtat attgtttcat gcacttagga aaataggtat tcccacaatc
     4681 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     4741 aaagagaaac tttctgcgga aattgtaatc aaacagaagg tagaactgca tcctaatatg
     4801 cgtgtaatga actttaccga atctgaacaa tgggatatgg taatagaagg aaatgattac
     4861 cttttggaga aatatacgtc tgggaaatta ttggaagcat tagaactcga acaagaggaa
     4921 agcataagat ttcataattg ttccctgttc cctgtttatc acggaagtgc aaaaaacaat
     4981 atagggattg ataaccttat agaagtgatt acgaataaat tttattcatc aacacatcga
     5041 ggtcagtctg aactttgcgg aaaagttttc aaaattgagt attcggaaaa aagacagcgt
     5101 cttgcatata tacgtcttta tagtggcgta ctgcatttgc gagattcggt tagaatatcg
     5161 gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa taaatggtga attatgtaaa
     5221 atcgataagg cttattccgg ggaaattgtt attttgcaga atgagttttt gaagttaaat
     5281 agtgttcttg gagatacaaa gctattgcca cagagagaga gaattgaaaa tcccctccct
     5341 ctgctgcaaa cgactgttga accgagcaaa cctcaacaaa gggaaatgtt acttgatgca
     5401 cttttagaaa tctccgacag tgacccgctt ctgcgatatt atgtggattc tgcgacacat
     5461 gaaatcatac tttctttctt agggaaagta caaatggaag tgacttgtgc tctgctgcaa
     5521 gaaaagtatc atgtggagat agaaataaaa gagcctacag tcatttatat ggaaagaccg
     5581 ttaaaaaaag cagagtatac cattcacatc gaagttccac cgaatccttt ctgggcttcc
     5641 attggtctat ctgtagcacc gcttccatta gggagcggag tacagtatga gagctcggtt
     5701 tctcttggat acttaaatca atcgtttcaa aatgcagtta tggaggggat acgctatggc
     5761 tgtgaacaag gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc
     5821 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
     5881 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
     5941 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
     6001 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
     6061 tgtattcaag aatatcgtag tgatttaact tcctttacaa atggacgtag tgtttgttta
     6121 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     6181 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     6241 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     6301 ttaaagtgta aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg
     6361 tggaaataaa acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta
     6421 ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat
     6481 tacagagcca gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta
     6541 tcggctcttt ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt
     6601 gataccgctg gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta
     6661 tttctctatc tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc
     6721 atcaacggaa acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg
     6781 ccctttattt tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg
     6841 ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa
     6901 atcatattta tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta
     6961 ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa
     7021 aaagcactac taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta
     7081 aaatattgta tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac
     7141 atcatataca ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa
     7201 tagataagta cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat
     7261 gtaaacagag aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa
     7321 gtttatttat cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag
     7381 ataaacgagc aaggctcact tcctttccta gacagaaagg gggtgagaaa catgaaacca
     7441 tcttcttttc agaccacaat agaaaatcag tttgactata tctgtaaacg tgctatggaa
     7501 gacgagcgaa agaattatat gctttatctt tcaaggattg caaagcgtga ggtgtccttt
     7561 tcggatgttg gcgattatct tgttagccag tttgcgacaa cagataacta ttcaactgac
     7621 tttcagattt ttacactcaa tgggttatca gtaggcgttg aaaatgattt gttgagtgaa
     7681 gcattacgtg agttgccaga caagaaacgt gaaattctac tgctgtttta ctttatggac
     7741 atgagcgatt cagaaattgc agacctgttg aaattgaacc gttctactgt ctatcggcat
     7801 agaaccagtg gactagcctt aattaaaaag tttatggagg aatttgaaga atgaaaacac
     7861 aatatcctat gattcccttt cctctcattg taaaggcaac agatggcgat accgaagcga
     7921 ttaaccagat tctacatcat tacagagggt acataacgaa gcgttcccta cgacttatga
     7981 aagatgaata tggcaatcaa agtatggtcg ttgatgaagt cttacgtgga agaatggaaa
     8041 ccagactgat tacaaagatt ttgtcatttg aaattaagta atatcctctc tcctttcgtg
     8101 gaagcgtgct aaaccattcc acgcttcccg aacagggagg tttgttattc caccaaagca
     8161 tattgagctt tcaatgtgtt ttgataggct aacgagccat tgttctttga aaactgaata
     8221 aaagtaatcg aatacgtttc gataagaaaa gagccaacgg aactaaccgc catgacctat
     8281 cttataaaga tagcgagcga ttcatgttag tgatccgaga agcaatcttt agcaggattg
     8341 cctgcaacga cattcttatc gtgataatga tactcccata cagtcaatag tccgagcgtg
     8401 ataaaaccgt cgcaggcaat gagtatggct acatgagaac catgcagggg tggaactccc
     8461 gtgagctttg ctaaagctgt tcgattgctg gtaaaacaac ttttatgaaa tccaaataag
     8521 tgatttggaa aggaggattt tatgaagcag actgacattc ctatttggga acgttatacc
     8581 ctaaccattg aagaagcgtc aaaatatttt cgtattggcg aaaacaagct acgacgcttg
     8641 gcagaggaaa ataaaaatgc aaattggctg attatgaatg gcaatcgtat tcagattaaa
     8701 cgaaaacaat ttgaaaaaat tatagataca ttggacgcaa tctagcgtcg ccaaagggtc
     8761 ttgtatatga taaaatagta ttaagtcgta tcaaggctct ttccataaag gaaaggagca
     8821 aatgccatgt cagaaaaaag acgtgacaat aaaggtcgaa tcttaaagac tggagagagc
     8881 caacgaaaag acggaagata cttatacaaa tatatagatt catttggaga accgcaattt
     8941 gtttactcgt ggaaacttgt ggctacagac cgagtaccag caggaaagcg tgattgtatc
     9001 tcacttagag agaaaatcgc agagttacag aaagacattc atgatggtat tgatgttgta
     9061 ggaaagaaaa tgacactctg ccagctttac gcaaaacaga acgctcaaag accaaaggtt
     9121 agaaaaaaca ctgaaactgg acgcaaatat cttatggata ttttgaagaa agacaagtta
     9181 ggtgtaagaa gtattgacag tattaagcca tcagacgcta aagaatgggc tattagaatg
     9241 agtgaaaatg gttatgctta tcaaaccatc aataactaca aacgttcttt aaaggcttca
     9301 ttctatattg ctatacaaga tgattgtgtt cggaagaatc catttgactt tcaactgaaa
     9361 gcagttcttg atgatgatac tgtccctaag accgtactaa cagaagaaca ggaagaaaaa
     9421 ctgttagcct ttgcaaaagc tgataaaacc tacagcaaaa attatgatga aattctgata
     9481 ctcttaaaaa caggtcttcg tatttcagag tttggtggtt tgacacttcc agatttagat
     9541 tttgagaatc gtcttgtcaa tatagaccat cagctattga gagatactga aattgggtac
     9601 tacattgaaa caccaaagac caaaagtggc gaacgtcaag ttcctatggt tgaagaagcc
     9661 tatcaagcat ttaagcgagt gttagcgaat cgaaagaatg ataagcgtgt tgagattgat
     9721 ggatatagtg atttcctctt tcttaataga aagaactatc caaaagtggc aagtgattac
     9781 aacggcatga tgaaaggtct tgttaagaaa tacaataagt ataacgagga taaattgcca
     9841 cacatcactc cacatagttt gcgacataca ttctgtacca actatgcaaa tgcaggaatg
     9901 aatccaaagg cattacagta cattatggga catgctaata tagccatgac gctgaactat
     9961 tacgcacatg caacattcga ttctgcaatg gcagaaatga aacgcttgaa taaagagaag
    10021 caacaggagc gtcttgttgc ttagtagtac aaatgaattt actacttatt taccacttct
    10081 gacagctaag acatgaggaa atatgcaaag aaacgtgaag tatcttccta cagtaaaaat
    10141 actcgaaagc acatagaata aggctttacg agcatttaag aaaatataaa aagataatta
    10201 gaaatttata ctttgttttt attaaaaagc agcaaactat aaactagtag gttccacact
    10261 aaatgtagcc ccatactgcc ccacaagtcc gatttatagc gtaccatccc taaaaacatt
    10321 cccaatgaaa catataaaca ccaagctaga atggttcctg gatga
//
